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New York Jets Flight Connections 04/05/26

Happy Easter Sunday, Jets fans! Below are your links for the day. Brian Costello – What Jets might do at quarterback in 2026 NFL Draft Rich Cimini – With Sabres playoff berth, Jets own longest active playoff drought Andrew Crane – Jets now by themselves for longest-active playoff drought with Sabres clinching berth after 14 […]

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Apr 5 • 7:00 AM EDT • Sports • sports.yahoo.com
Missing crew member rescued by US forces after jet downed in Iran, Trump announces

A missing US crew member whose fighter jet was shot down over Iran has been rescued by US forces, President Donald Trump said in a Truth Social post early Sunday.

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Apr 5 • 12:29 AM EDT • Politics • cnn.com
White House Forced to Address Claims of Trump Health Crisis

Administration officials aren’t having any of the gossip about the president’s health.

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Apr 4 • 6:43 PM EDT • Health • thedailybeast.com
Trump’s Victory Rhetoric Undercut by Downed US Jet in Iran War

The downing of a US aircraft and the dayslong search for a missing crew member has pierced the aura of invincibility that President Donald Trump has sought to project as he tries to stave off the increasing political risks of the Iran war he started five weeks ago alongside Israel.

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Apr 4 • 12:58 PM EDT • Politics • bloomberg.com
U.S.-Iran war 'tax' begins to hit American businesses and consumers

A U.S.-Iran war 'tax' is beginning to hit consumers as diesel and jet fuel prices rise and stress business profitability, and there is no relief in sight.

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Apr 4 • 9:16 AM EDT • Business • cnbc.com
Cabinet shake-ups mark a new phase for Trump: From the Politics Desk

Plus, a U.S. fighter jet goes down over Iran.

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Apr 3 • 5:00 PM EDT • Politics • nbcnews.com
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Downed fighter jet punctures Trump’s and Hegseth’s claims of air invulnerability

An Iran war that was already proving quite unpopular with the American people has entered a new, more problematic phase for President Donald Trump.

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Apr 3 • 4:07 PM EDT • Politics • cnn.com
Despite soaring jet fuel prices, air fares aren’t up that much. But they will be

Gas prices are grabbing the headlines, but jet fuel prices have doubled in the last two months. So far, air fares are only up modestly.

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Apr 3 • 7:00 AM EDT • Business • cnn.com
Labour challenges Farage over cost of private jet trip to Maldives

Anna Turley questions Reform UK leader’s revised £25,000 figure for failed attempt to reach Chagos Islands on plane linked to billionaire donor

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Apr 3 • 4:21 AM EDT • Politics • theguardian.com
New York Jets WR Rumors Intensify

Will the Jets add a veteran WR to the mix?

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Apr 2 • 2:00 PM EDT • Sports • sports.yahoo.com
2026 NFL seven-round mock draft: Steelers, Jets, Cardinals among teams targeting QBs as 11 come off the board

From the No. 1 overall pick to Mr. Irrelevant, here's how every team builds its 2026 class.

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Apr 2 • 9:51 AM EDT • Sports • cbssports.com
Aaron Glenn obsessed with making good on his 'unfinished' Jets business

Now that he is in his second year as head coach and consumed with the day-to-day details of the job, how often does he think of that larger goal?

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Mar 31 • 6:40 PM EDT • Business • nypost.com
2026 NFL Draft: From the Broncos to the Jets, ranking every NFL team by the value of their picks

Five teams have two picks in the first round of the 2026 NFL Draft

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Mar 31 • 9:35 AM EDT • Sports • cbssports.com
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Bruce Springsteen brings 'Streets of Minneapolis' home to launch a political US tour

Bruce Springsteen returns Tuesday to the “Streets of Minneapolis.”.

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Mar 31 • 12:05 AM EDT • Politics • news4jax.com
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Bruce Springsteen brings 'Streets of Minneapolis' home to launch a political US tour

Bruce Springsteen returns Tuesday to the “Streets of Minneapolis.”.

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Mar 31 • 12:05 AM EDT • Politics • wsls.com
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JetBlue hikes checked bag fees, citing rising operating costs

JetBlue said it hiked fees for "optional services" like checked baggage due to "rising operating costs," as the cost of jet fuel rises.

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Mar 30 • 10:30 PM EDT • Business • businessinsider.com
Sysco goes all in on the ‘cash and carry’ food-service business with a $29 billion buyout

Sysco’s stock falls after announcing a $29.1 billion cash-and-stock deal to buy Jetro Restaurant Depot.

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Mar 30 • 8:00 AM EDT • Business • marketwatch.com
Preview: Colorado’s Roundtrip Flight with Winnipeg Concludes Tonight

The Colorado Avalanche wrap up their season series against the Winnipeg Jets today!

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Mar 28 • 9:00 AM EDT • Sports • sports.yahoo.com
New York Jets Flight Connections 03/28/26

Happy Saturday, Jets fans! Below are your links to kick off this weekend as we keep cruising toward the 2026 NFL Draft. NY Jets – Where Have the Jets Improved their Roster Most this Offseason? Jack Bell – Jets QB Geno Smith: Aaron Glenn is a ‘Special Coach’ Jack Bell – At No. 2 Overall […]

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Mar 28 • 7:00 AM EDT • Sports • sports.yahoo.com
How baseball imitates life: Authors share tips for sports parents

What do Derek Jeter, Yoshinobu Yamamoto and "Seinfeld" have in common? They provide examples of how baseball lessons can help our kids succeed.

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Mar 28 • 5:06 AM EDT • Sports • usatoday.com
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Potential New Look Buccaneers Linebacking Core Following David's Retirement
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Mar 27 • 3:19 PM EDT • Sports • sports.yahoo.com
China Deploys Jet-Converted Drones Near Taiwan Strait

China has also been investing heavily in more advanced drone technologies, including stealth UAVs and carrier-based unmanned systems.

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Mar 27 • 3:05 AM EDT • Politics • politicstoday.org
Hydrogen-powered business jet edges closer to certification

If you've ever hankered after a hydrogen-powered business jet, your wait might not be much longer. French aerospace startup Beyond Aero's BYA-I One aircraft has completed its Preliminary Design Review, pushing it along the path to certification.

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Mar 27 • 1:39 AM EDT • Business • newatlas.com
United's upcoming SFO routes literally squeeze out the budget traveler

United serves caviar to premium travelers aboard new jet. Coach gets better blankets.

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Mar 26 • 4:25 PM EDT • Business • sfgate.com
Glyphosate: A story of science, risk, and nuance

In the summer of 2014, a California groundskeeper named Dewayne Johnson started noticing patches of raw, weeping skin spreading across his body. He had spent years applying Roundup, Monsanto’s glyphosate-based herbicide, for a school district, sometimes drenched in it when equipment malfunctioned. By 2014, he had a diagnosis: non-Hodgkin’s lymphoma. In 2018, a jury awarded him $289 million in damages, later reduced on appeal. Tens of thousands of lawsuits followed. The story hasn’t quieted down. It’s all over the internet, swinging between “this will kill you, buy organic” and “relax, you’re fear-mongering.” Some of that recent chatter stems from an Executive Order protecting glyphosate and its production, which set off intense infighting within the MAHA movement. Some of it reflects a deeper truth: Americans genuinely care about harmful chemicals in their environment (see poll below). And the conversation isn’t going anywhere, with a Supreme Court case involving Monsanto set for this April. Glyphosate (the active ingredient in Roundup) is one of the most widely used herbicides in the world. But does glyphosate cause cancer? And how much exposure is actually risky? With so much mistrust in institutions and corporations (and some genuine conflicts of interest), making sense of the actual scientific evidence is genuinely hard. Here is a translation of what the scientific evidence actually says. Does glyphosate cause harm? Glyphosate is an herbicide that kills most plants it contacts rather than targeting specific species. It works by blocking an enzyme pathway (EPSPS) that plants and many microorganisms need to produce essential amino acids. Without those amino acids, the plant can’t grow and dies. Glyphosate was first developed by Monsanto in the 1970s and became ubiquitous after the company introduced “Roundup Ready” crops in the 1990s. In 2024, Bayer removed glyphosate from residential Roundup-branded products due to litigation pressure. But today it is still the most widely used herbicide in the world. Farmers also discovered they could spray it directly on crops like oats, lentils, beans, and peas just before harvest to dry them out faster and make harvesting easier. Because of its widespread use, it’s obviously really important to understand if it’s harmful to humans. The key principle: The dose makes the poison The most important concept in toxicology is that “the dose makes the poison.” Sixteenth-century physician Paracelsus articulated what remains the foundational principle of toxicology: sola dosis facit venenum. Water will kill you if you drink enough of it. Aspirin saves lives at 81 milligrams and causes internal bleeding at higher chronic doses. So, at what dose is glyphosate poisonous? The LD50 in rats (the dose that kills half the test animals) is around 5,600 mg/kg body weight. Table salt is roughly 3,000 mg/kg. By that classic measure, glyphosate is less acutely toxic than salt. But some people are exposed to a lot of glyphosate through their work. And among the general public, there are many questions about low-dose, cumulative exposure from multiple sources over long periods. Does glyphosate cause health problems? Cancer Correlation maps are striking, with one analysis finding that 60% of counties that spray the most glyphosate have non-Hodgkin’s lymphoma rates above the national average. But correlation alone doesn’t establish cause, which is why animal and human studies matter. In animals: Rat studies are typically what most fear is rooted in, but most people don’t know the study details on the dosage given to rats. A pooled analysis of the 13 most rigorous rat studies found evidence that very high doses, around 55,000 times greater than typical food residue exposure, can cause certain cancers. In humans: One of the strongest studies followed 55,000 herbicide users over 20 years and found no overall increased cancer risk. There was one signal: among those with the highest use, rates of acute myeloid leukemia (AML) appeared elevated. A broader meta-analysis of 18 human studies also found no overall cancer risk, though a separate meta-analysis focused specifically on non-Hodgkin lymphoma found that people with high cumulative glyphosate exposure faced a 41% higher relative risk compared to those with low or no exposure. These human studies are observational studies (randomized controlled trials would be unethical), and meta-analyses are only as reliable as the studies they pool. But the story seems consistent: at very high exposure levels, there may be some cancer risk. But that’s about as far as the science currently takes us. Emerging research: gut and reproductive health Gut: Because glyphosate targets a pathway that exists in some gut bacteria, scientists have questioned whether it could affect the microbiome. In mice, a 2023 University of Iowa study found that glyphosate altered gut bacterial composition and raised markers of intestinal inflammation. A 2024 systematic review found similar patterns: disrupted gut bacteria and problems with the mucus layer that protects the intestinal wall in mice. Whether this translates to humans is an open question. The human gut is highly variable and resistant, and we don't yet have strong studies confirming the same effects in people. Reproductive health: Animal studies have found that glyphosate-based herbicides can interfere with reproductive hormones, including disrupting egg cell development in mice and reducing the number of eggs available in sheep’s ovaries. However, the doses used in these experiments were high, so it’s not yet clear whether the same effects would occur in humans. On the human side, a 2021 pilot study led by Mount Sinai researchers tested urine samples from pregnant women across the U.S. and found glyphosate in 95% of them. The study also found a possible connection between higher glyphosate exposure during pregnancy and a subtle physical difference measured in female newborns. That said, some connections weren’t statistically reliable and this was a small study. The researchers themselves said more and larger studies are needed before drawing firm conclusions. What do regulators say about glyphosate safety? In 2015, the International Agency for Research on Cancer (IARC), part of the World Health Organization, classified glyphosate as "probably carcinogenic to humans" (Group 2A). The classification is worth taking seriously. But, there’s an important distinction: IARC classifies hazard, meaning the potential to cause harm under some conditions. It does not assess risk, which accounts for actual exposure levels and the real-world probability of harm. The U.S. EPA, the European Food Safety Authority, Health Canada, and regulatory agencies in Australia and Japan have all concluded that glyphosate is “unlikely to be carcinogenic to humans” at realistic exposure levels. They’re asking a different question: given how much of this people actually encounter, what is the probability of harm? Your actual exposure is what determines your actual risk. What does glyphosate mean for your daily life? At the grocery store: Food residues are small. The EPA’s acceptable daily intake is 1.75 mg/kg of body weight per day. To hit that threshold from oatmeal alone, a 150-pound adult would need to eat roughly 50 pounds of oats every day. But this calculation addresses only one pathway (food), and we don’t yet have robust tools to measure people’s actual total exposure. If reducing exposure matters to you, organic certification prohibits synthetic herbicides, and organic oat products generally test at lower or undetectable levels. Either way, a diet rich in whole grains, conventional or organic, is far better for your health than one that omits them out of fear of residues. On the farm: Occupational exposure is orders of magnitude higher than consumer exposure. Farmers and farm workers who mix, load, and apply glyphosate-based herbicides, especially without protective equipment, face meaningfully different risk profiles. Proper PPE isn’t optional. Integrated weed management strategies that rotate chemical modes of action are also worth taking seriously, both for health and for long-term effectiveness. If you live near a farm: Spray drift is real. Concentrations near field edges can spike during and after application, particularly on windy days. This is an area where I think public health could really step up and empower rural communities with buffer zones, rather than placing the onus on individuals. But for now, knowing your local agricultural calendar and keeping windows closed during application are the first steps. Bottom line Dewayne Johnson was exposed to glyphosate at levels most people will never encounter, and a jury decided he deserved compensation. That outcome is not evidence that the oatmeal in your pantry is dangerous. But it is a reminder that the dose, the context, and the person doing the exposing all matter enormously. Glyphosate is a chemical tool with benefits, trade-offs, and genuine open scientific questions. Learning to hold that complexity without collapsing into panic or dismissal is, honestly, one of the most useful and hardest things to do in navigating modern health science. Love, YLE Your Local Epidemiologist (YLE) is founded and operated by Dr. Katelyn Jetelina, MPH PhD—an epidemiologist, wife, and mom of two little girls. Hannah Totte, MPH, is an epidemiologist and YLE Community Manager. YLE reaches more than 425,000 people in over 132 countries with one goal: “Translate” the ever-evolving public health science so that people will be well-equipped to make evidence-based decisions. This newsletter is free to everyone, thanks to the generous support of fellow YLE community members. To support the effort, subscribe or upgrade below: Subscribe

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Mar 25 • 10:25 AM EDT • Science • yourlocalepidemiologist.substack.com
After Providence Health Plan Outsourcing Fiasco, the Cleanup Continues

One of Oregon’s largest health insurance plans announced in recent days it might be going up for sale but, in the meantime, it still has quite a bit of cleaning up to do.

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Mar 24 • 9:09 PM EDT • Health • wweek.com
Your Thymus and Your Healthspan

Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.

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Mar 22 • 2:18 PM EDT • Health • erictopol.substack.com
United Airlines Just Issued a Playbook for Any Business Staggered by Skyrocketing Costs

In a letter to employees, CEO Scott Kirby delivered a master class on boosting morale as he deals with the impact of surging jet fuel prices.

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Mar 22 • 1:52 PM EDT • Business • inc.com
A Grip on Sports: In a season when Gonzaga's defense was the driving force behind its success, the Zags couldn't get the one stop they needed

A GRIP ON SPORTS • After all the flotsam and jetsam is swept away, sometimes a college basketball game, an NCAA Tournament game, comes down to making one play. Saturday night in Portland, Texas did. And Gonzaga’s season once again fell short of its ultimate goal.

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Mar 22 • 3:16 AM EDT • Sports • spokesman.com
Top business aviation banker talks debt, profits, JetGate, EBITDAR

Jefferies' Nick Fazioli on why Wall Street loves private jets, non-GAAP financial metrics and why past results don't preclude more investment

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Mar 21 • 1:51 PM EDT • Business • privatejetcardcomparisons.com
Public Skate: Bruins vs. Jets

This may surprise you, but it’s another big game!

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Mar 19 • 5:00 PM EDT • Sports • sports.yahoo.com
Providence May Sell Off Health Insurance Business

The Providence Health Plan was already outsourcing some of its core functions, but had previously denied it had plans to sell.

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Mar 19 • 3:00 PM EDT • Business • wweek.com
Providence May Sell Off Health Insurance Business

The Providence Health Plan was already outsourcing some of its core functions, but had previously denied it had plans to sell.

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Mar 19 • 3:00 PM EDT • Health • wweek.com
Jeffrey Epstein's personal lawyer explains large cash withdrawals

Darren Indyke says Jeffrey Epstein needed a lot of cash for his lavish lifestyle, including a jet, a private island, and homes around the world.

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Mar 19 • 2:00 PM EDT • Business • businessinsider.com
I Flew JetBlue Business Class to London and Came Home a Fan

Our columnist traveled via Mint service on the underdog airline from JFK to Heathrow.

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Mar 17 • 9:00 PM EDT • Business • wsj.com
NFL news, free agency updates: Dolphins reportedly trade WR Jaylen Waddle to Broncos; Jets trade Justin Fields to Chiefs in exchange for 6th-round pick
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Mar 17 • 11:24 AM EDT • Sports • sports.yahoo.com
Nine most intriguing defensive additions during 2026 NFL free agency so far

Can Minkah Fitzpatrick and T'Vondre Sweat help reboot the Jets defense?

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Mar 17 • 9:38 AM EDT • Sports • cbssports.com
Buccaneers Bring Back Feeney for OL Depth
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Mar 17 • 12:39 AM EDT • Sports • sports.yahoo.com
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Chiefs Reportedly Make Trade With Jets For Former Steelers QB

Justin Fields is on the move again. On Monday, NFL insider Adam Schefter reported that the New York Jets are reportedly trading Fields to the Kansas City Chiefs in exchange for a 2027 sixth-round draft pick. The deal is still pending a physical. Other teams were reportedly interested in Fields, but his preference was to […]

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Mar 16 • 5:26 PM EDT • Sports • sports.yahoo.com
Former Steelers quarterback traded to Chiefs

The New York Jets are dealing ex-Pittsburgh starting QB to Kansas City

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Mar 16 • 1:36 PM EDT • Sports • sports.yahoo.com
Africa’s Business Aviation Rebirth

Africa's business aviation sector has lived under the weight of a stubborn global stereotype: a continent defined by ageing aircraft, fragmented regulation and limited economic prosperity.

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Mar 15 • 8:00 PM EDT • Business • aviationweek.com
Top 5 most improved teams during NFL free agency, including the lowly Jets

After an initial flurry of moves, the NFL free agent market has slowed down. Here are the teams that have made the biggest improvements so far.

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Mar 15 • 7:02 AM EDT • Sports • usatoday.com
Photos: JetBlue's first airport lounge, BlueHouse

JetBlue opened its first luxury lounge at JFK International Airport last year. As a lounge rookie, I knew this was my chance to elevate my experience.

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Mar 14 • 6:07 AM EDT • Business • businessinsider.com
Airline ticket prices surge on United, Delta, and American: charts

Jet fuel is typically airlines' biggest expense after labor. Most US airlines do not hedge against fuel costs, unlike other carriers around the world.

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Mar 13 • 1:53 PM EDT • Business • businessinsider.com
Dassault reveals Falcon 10X with largest cabin in business aviation

Dassault Aviation has unveiled the Falcon 10X ultra-long-range business jet with spacious cabin and a 7,500-nautical-mile range.

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Mar 12 • 7:43 AM EDT • Business • aerospaceglobalnews.com
Antwan Staley: Jets and Geno Smith need each other

NEW YORK — What’s old is new again. Since 2013, the New YorkJets have had 13 different starting quarterbacks. But all veteran bridge options brought them back to Geno Smith. Nearly a decade after his departure, the Jets brought Smith back on Tuesday after agreeing to a trade with the Las Vegas Raiders. The biggest question many are asking is why the Jets would bring back Smith after his first ...

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Mar 12 • 5:30 AM EDT • Sports • sports.yahoo.com
Textron (TXT) Wins Mario Gabelli’s Support on Growth in Business Jets and V-280 Defense Program

Textron Inc. (NYSE:TXT) is one of the best stocks to buy according to billionaire Mario Gabelli. Textron Inc. (NYSE:TXT) is one of the companies in GAMCO Investors’ portfolio where the hedge fund has actually increased its stake from its position from more than a decade ago. As of the end of Q4 2025, GAMCO had 1.38 […]

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Mar 11 • 5:22 PM EDT • Business • finance.yahoo.com
Dolphins trade veteran safety Minkah Fitzpatrick to Jets
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Mar 11 • 4:39 PM EDT • Sports • sports.yahoo.com
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Satellite images show strikes turning Iran's vintage F-14s into wrecks

Iran is the only country still flying the F-14 Tomcat, a jet iconized by the 'Top Gun' films. Images from the war show fresh damage to the fleet.

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Mar 11 • 11:24 AM EDT • Business • businessinsider.com
Dassault Aviation unveils long-range Falcon 10X business jet

Dassault Aviation rolled ​out its latest long-range ‌business jet, the Falcon 10X, on ​Tuesday, marking a ​key public milestone as the ⁠French planemaker challenges ​larger North American ​rivals at the top end of the luxury aircraft ​market.

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Mar 10 • 3:04 PM EDT • Business • reuters.com
Minkah Fitzpatrick traded to Jets: Dolphins continue roster overhaul, deal star safety for seventh-rounder

Fitzpatrick remains in the AFC East and gets a new contract

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Mar 9 • 9:48 AM EDT • Sports • cbssports.com
Private jet used for Nigel Farage Chagos stunt linked to Reform mega-donor

Exclusive: Plane that flew Reform leader to Maldives appears to be linked to billionaire Christopher Harborne

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Mar 8 • 1:00 PM EDT • Politics • theguardian.com
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2026 NFL free agency mock draft: Kyler Murray to Jets, Mike Evans to 49ers, plus 30 more projected moves

Teams with the most salary cap space get the first "picks" in this free agency mock draft.

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Mar 7 • 9:37 AM EST • Sports • cbssports.com
Reality is immaterial in today's politics

Republicans are having a field day over Bill Clinton's testimony that JB Pritzker flew on Jeffrey Epstein's jet. But Democrats are also succumbing to fantasy worlds of their own making.

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Mar 6 • 6:00 PM EST • Politics • chicago.suntimes.com
RAF jets could legally strike Iran’s missile bases, says David Lammy

Deputy prime minister says while jets currently only shooting down missiles, there is legal basis for them to do more

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Mar 6 • 4:31 AM EST • Politics • theguardian.com
The Jets are considering two veteran starting quarterbacks per reports

The Jets need to find a starting quarterback in 2026. There aren’t many quality options on the market. However, over the last few days a pair of teams announced they were moving on from big money veteran starting quarterbacks. The Cardinals are parting ways with Kyler Murray after seven years, while the Dolphins are doing […]

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Mar 4 • 4:19 PM EST • Sports • sports.yahoo.com
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American Express Expands Global Sports and Entertainment Footprint with New Stadium and NFL Team Partnerships

NEW YORK, March 04, 2026--American Express (NYSE:AXP) will soon offer exclusive access, value and experiences for Card Members in the New York/New Jersey and Atlanta metropolitan areas through new long-term partnerships. American Express will be named the Official Payments Partner of MetLife Stadium, the New York Jets, the New York Giants, Mercedes-Benz Stadium, the Atlanta Falcons, Atlanta United and the newly awarded National Women’s Soccer League (NWSL) team which will begin play in 2028. Thi

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Mar 4 • 11:00 AM EST • Entertainment • finance.yahoo.com
American Express Expands Global Sports and Entertainment Footprint with New Stadium and NFL Team Partnerships

New Partnerships with MetLife Stadium & Jets Will Deliver Exclusive Access and Experiences for Card Members

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Mar 4 • 11:00 AM EST • Entertainment • newyorkjets.com
American Express Expands Global Sports and Entertainment Footprint with New Stadium and NFL Team Partnerships

New Partnerships with MetLife Stadium & Jets Will Deliver Exclusive Access and Experiences for Card Members

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Mar 4 • 11:00 AM EST • Sports • newyorkjets.com
Jon Rahm provides jet to get LIV golfers from Dubai to Hong Kong amid U.S. war with Iran, per report

Seven players who live in Dubai took a plane provided by Jon Rahm to Hong Kong for this week's event

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Mar 4 • 10:14 AM EST • Sports • cbssports.com
Takeaways from Kristi Noem’s combative Senate Judiciary Committee hearing

Senators grilled Noem about her early descriptions of two US citizens who were killed by federal officers in Minneapolis, her use of executive jets and whether ICE will be sent to polling places

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Mar 3 • 3:09 PM EST • Politics • cnn.com
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RAF F-35 stealth fighter jets just scored their first-ever combat kill

British forces have shot down drones across the Middle East over the past day as Iran continues to strike.

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Mar 3 • 2:02 PM EST • Business • businessinsider.com
Curiosity Blog, Sols 4818-4824: Thinking Out of the Boxwork

Written by Ashley Stroupe, Operations Systems Engineer at NASA’s Jet Propulsion Laboratory

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Mar 3 • 1:40 PM EST • Science • science.nasa.gov
NFL news, live updates: Jets reportedly franchise tag RB Breece Hall ahead of Tuesday's deadline; Seahawks not expected to tag Kenneth Walker III
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Mar 3 • 12:17 PM EST • Sports • sports.yahoo.com
NFL news, live updates: Jets reportedly franchise tag RB Breece Hall ahead of Tuesday's deadline; Lions trade RB David Montgomery to Texans
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Mar 3 • 11:44 AM EST • Sports • sports.yahoo.com
NFLPA Report Card Ranks Buccaneers 29th among NFL Teams
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Mar 2 • 12:22 AM EST • Sports • sports.yahoo.com
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Arizona Cardinals OL Isaiah Adams 2026 offseason profile

A look at OL Isaiah Adams' season, his contract and what to expect in the offseason.

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Mar 1 • 10:28 PM EST • Sports • sports.yahoo.com
Sharks edge Jets 2-1 on Misa OT goal

Michael Misa scored 1:40 into overtime, and the San Jose Sharks topped the Winnipeg Jets 2-1 on Sunday for their second straight win. Misa scored for the second straight game when he drove down the slot before beating Winnipeg goaltender Connor Hellebuyck. It was the fourth goal of the season for the No.

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Mar 1 • 8:42 PM EST • Sports • sports.yahoo.com
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Israel bombing vintage US-made fighter jets in Iran

Video footage shows the Israel Defense Forces striking two F-4 and F-5 fighters before they took off from an airport in western Iran.

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Mar 1 • 10:32 AM EST • Business • businessinsider.com
Soundcore’s New Headphones Have an Absurd Battery Life for the Price

The ANC is supposed to be able to block out jet engines, too.

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Mar 1 • 10:00 AM EST • Technology • gizmodo.com
New York Jets Flight Connections 03/01/26

Happy Sunday, Jets fans. Below are your daily Jets links. Robby Sabo – Aaron Glenn’s sleepiness isn’t the ‘Dunk on NY Jets’ you think it is Sharif Phillips-Keaton – Jets’ Aaron Glenn, Darren Mougey earn A’s in 2026 NFLPA report cards Stephen Parello – Jets’ Jermaine Johnson trade could fully unlock a Will McDonald breakout […]

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Mar 1 • 7:00 AM EST • Sports • sports.yahoo.com
Relief Pitcher Sleepers for 2026 Fantasy Baseball
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Mar 1 • 2:06 AM EST • Sports • sports.yahoo.com
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Bay Area sports calendar, March 1-2

Dmitry Orlov and the Sharks will face the Jets at 1 p.m. Sunday. (NBCSCA)

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Mar 1 • 1:00 AM EST • Sports • sports.yahoo.com
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NFL scouting combine winners and losers: Wake up, Jets! There's a shot with this reboot. And Texas Tech's David Bailey looks tremendous
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Feb 28 • 8:20 PM EST • Sports • sports.yahoo.com
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Israel says 200 fighters struck Iran, its largest-ever air operation

The Israeli fighter jets, which included F-35s and F-15s, dropped hundreds of bombs on roughly 500 targets.

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Feb 28 • 2:02 PM EST • Business • businessinsider.com
Bombardier has chance to boost business jet sales in India, says CEO

MONTREAL, Feb 26 () - ‌India's ‌efforts to ​improve its airport infrastructure ‌will ⁠give Bombardier a ⁠chance ​to ​boost ​sales ‌of business jets there, chief ‌executive ​officer ​Eric ​Martel ‌told reporters on ​Thursday. (Reporting ​by Allison ​Lampert, ‌editing ​by David ​Ljunggren).

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Feb 26 • 2:14 PM EST • Business • finance.yahoo.com
Covington Municipal Airport Partners with Air Charter Advisors to Expand Business Aviation Access

Strategic collaboration streamlines on-demand private jet travel for East Atlanta's growing industrial and film production sectors.Covington, Georgia--(Newsfile Corp. - February 26, 2026) - Covington Municipal Airport (KCVC) has announced a formal partnership with Air Charter Advisors to coordinate on-demand private aviation services from its Newton County facility. The agreement strengthens transportation infrastructure for the region's expanding bioscience, advanced manufacturing, and film...

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Feb 26 • 11:21 AM EST • Business • finance.yahoo.com
Possible bullet holes mysteriously appear on American Airlines plane after flight from Colombia

American Airlines jet discovered with possible bullet holes after Miami landing from Colombia. Aircraft grounded for investigation following inspection.

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Feb 24 • 11:34 PM EST • Business • foxbusiness.com
Brazil's Embraer announces new variants of Praetor business jets

Brazilian planemaker Embraer announced on Tuesday new variants of its Praetor business jets as it seeks to capitalize on heated global demand for executive aircraft.

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Feb 24 • 11:16 AM EST • Business • reuters.com
Technology Originally Developed for Space Missions Now Integral to Everyday Life

Groundbreaking “camera-on-a-chip” technology that was originally developed at NASA’s Jet Propulsion Laboratory (JPL) for use in space missions is currently employed in billions of devices like cell phones that are used daily by people worldwide.

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Feb 24 • 9:29 AM EST • Science • science.nasa.gov
Map: 39 flights to Puerto Vallarta, Guadalajara diverted amid violence

Two private jets and an 11-hour transatlantic journey from Madrid were among the flights that diverted due to cartel violence in Mexico.

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Feb 23 • 6:50 AM EST • Business • businessinsider.com
A new era for Dutch politics with Rob Jetten set to be sworn in as prime minister

The Netherlands is getting a new minority government led by Rob Jetten, the country’s youngest-ever prime minister

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Feb 23 • 2:13 AM EST • Politics • washingtonpost.com
A new era for Dutch politics with Rob Jetten set to be sworn in as prime minister

The Netherlands is getting a new minority government led by Rob Jetten, the country’s youngest-ever prime minister.

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Feb 23 • 2:09 AM EST • Politics • apnews.com
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A new era for Dutch politics with Rob Jetten set to be sworn in as prime minister
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Feb 23 • 2:09 AM EST • Politics • 10tv.com
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New York Jets Flight Connections 02/22/26

Happy Sunday, Jets fans! Here are your daily links to kick your day off. Michael Nania – Which Jets free agents are worth keeping at their market values?\ Michael Nania – NY Jets’ Breece Hall pushes for ‘better infrastructure’ with ‘Free20’ Antwan Staley – Jets should avoid drafting QB in 2026 NFL Draft, says NFL […]

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Feb 22 • 7:00 AM EST • Sports • sports.yahoo.com
New York Jets Potential Free Agent Options Part 1

First Look at Potential Jets Free Agent Options

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Feb 21 • 11:00 AM EST • Sports • sports.yahoo.com
Country music icon’s jet aborts takeoff due to mechanical failure. Here’s the latest

The country music legend had a frightening flight.

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Feb 21 • 8:15 AM EST • Entertainment • pennlive.com
How Mamdani's warning to city health clubs could help Long Island members

An executive order requires New York City heath clubs "to monitor, investigate, and enforce violations related to subscription tricks and traps."

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Feb 20 • 5:00 AM EST • Health • newsday.com
Ethan Hawke warns against looking to 'jet-lagged, drunk' actors for political wisdom

Ethan Hawke warned during a film festival in Germany that the opinions of entertainers are valid, in that they are people like anybody else, but not the first source to go to.

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Feb 17 • 7:10 PM EST • Politics • foxnews.com
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Canadian airlines pull back from flights to the US

Air Transat will no longer fly to the US this summer, while WestJet is also slashing several routes, as Canadian interest in visiting the US falls.

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Feb 17 • 11:25 AM EST • Business • businessinsider.com
How Jet Engines Are Powering Data Centers

Companies are converting aircraft engines to land-based natural gas turbines for power generation in the AI boom.

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Feb 17 • 5:30 AM EST • Business • wsj.com
Achilles Running Shop celebrates 20 years of business

Achilles Running Shop first opened its doors two decades ago. Since then, it’s grown into more than just a retail store, becoming a hub for the local running community From first-time 5K runners to ex...

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Feb 16 • 4:44 PM EST • Business • yourerie.com
What is the hardest coaching job in world sport?

From Real Madrid to the New York Jets via the USWNT, our writers pick out the most unforgiving coaching roles

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Feb 15 • 12:12 AM EST • Sports • nytimes.com
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Politics Take Center Stage at the Berlinale as Social Media Backlash Looms

As press conference remarks are clipped and amplified online, some filmmakers worry that speaking freely could invite instant backlash.

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Feb 14 • 2:00 PM EST • Politics • hollywoodreporter.com
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Charli xcx Brats Up Berlin: ‘The Moment’ Star Applauds the Fest for “Not Shying Away From Political Films,” Declares Brat Era “Over”

"I feel like I'm only just starting out," the Brit superstar said about crashing Hollywood with her mockumentary film.

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Feb 14 • 9:58 AM EST • Politics • hollywoodreporter.com
'It's absurd': DHS shutdown bears down on US as lawmakers jet off to Europe

Senators and members of the House headed to the Munich Security Conference without first securing a deal to fund DHS. Their colleagues aren't happy with the decision.

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Feb 13 • 1:42 PM EST • Politics • foxnews.com
Julie’s Sweet Treats officially open for business

A local chocolatier cut the ribbon on her new chocolate shop just in time for Valentine’s Day. Julie’s Sweet Treats, located on 6 East Main Street, is officially open for business and is celebrating i...

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Feb 13 • 12:29 PM EST • Business • yourerie.com
Congress Jets Off as D.H.S. Shuts Down

Despite a deadlock over funding for the agency, lawmakers left town and left Democratic and White House negotiators to try to work out a deal in their absence.

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Feb 13 • 10:04 AM EST • Politics • nytimes.com
Detroit Lions Predicted to Lose Defensive Captain to Former Coach

Could the Lions lose linebacker Alex Anzalone to Aaron Glenn’s Jets? Here’s why a reunion in New York is gaining momentum and what it means for Detroit.

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Feb 13 • 8:54 AM EST • Sports • detroitsportsnation.com
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“Wow”: Neil Patrick Harris Hit With Barrage of U.S. Politics Questions at Berlin ‘Sunny Dancer’ Presser: “I’m Interested in Things That Are Apolitical”

Bella Ramsey, Este Haim, and filmmaker George Jacques arrived at the Berlinale presser with Harris on Friday morning, where the group were asked if cinema can help fight fascism.

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Feb 13 • 7:35 AM EST • Politics • hollywoodreporter.com
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