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Denzel Boston quiet in Week 7 road win vs. Titans
Cleveland Browns wide receiver Denzel Boston registered three receptions for 27 yards on eight targets in Week 7
“Odegaard was outstanding” but Merson was less complimentary about Gyökeres
Paul Merson has delivered contrasting verdicts on two Arsenal players following Saturday’s comfortable 2-0 victory over Everton, singling out Martin Ødegaard for praise while questioning Viktor Gy�...
Iowa family finds strength beyond the gym after cancer diagnosis
URBANDALE, Iowa (KCCI) -- Azariah Townsend can barely reach the pull-up bar in his family’s home gym in Urbandale, but he already knows strength is not measured by height.
What’s going on with AJ Dybantsa’s ankle injury?
The Washington Wizards have started off playing well this season, and they’ve done so without the No. 1 overall pick. AJ Dybantsa hasn’t made his NBA debut yet as he deals with an ankle injury, and it looks like he’ll have to keep waiting after the latest update on his status, according to Brett Siegel of ClutchPoints. “AJ Dybantsa will remain […] The post What’s going on with AJ Dybantsa’s ankle injury? appeared first on ClutchPoints.
Dunwoody to discuss adding two entertainment districts
The Dunwoody City Council will discuss adding two new entertainment districts – Georgetown and Jett Ferry – at its meeting on Monday, Oct. 26.
Eye on Northwest Politics: Oct 25, 2026 (Christine Drazan)
Reporting Portland and Vancouver area breaking news and weather stories to make Oregon and Southwest Washington a better place to live
Susan MacManus sees working class voters continuing to change Florida's landscape
NPA voters could act differently than in prior pst-pandemic elections.
Veteran Makers Market highlights importance of supporting veteran-owned businesses
The Veteran Makers Market spotlights veteran-owned businesses, encouraging shoppers to support those turning military skills into local success.
Pistons' Ausar Thompson ruled out against Sixers
The Pistons will be without Ausar Thompson on Sunday night for their match against Philadelphia.
Pirates Should Re-Sign This Upcoming Free Agent
Gregory Soto could still be a solid piece in the Pittsburgh Pirates bullpen in 2027.
Molina Healthcare awards $15,000 grant to expand tribal cultural wellness initiative
Matthew Stafford breaks Rams franchise record for touchdown passes
LAS VEGAS (AP) — Matthew Stafford added another milestone to his NFL career on Sunday, throwing his 155th touchdown pass for the Los Angeles Rams to break the franchise record.Stafford surpassed Roman Gabriel, who threw 154 TD passes for the Rams from 1962-72.
A new state on the way? More Illinois counties could vote to leave Chicago behind
More than 30 counties have already approved the non-binding measure to leave Illinois
Democrat Coumba Kebe wants to keep the politics out of the treasurer’s office
Political newcomer Coumba Kebe is the Democratic nominee for Indiana state treasurer. Kebe wants to keep the politics out of the office and build back trust with people.
Ollie Gordon II surpasses 100-yard mark in Week 7
Dolphins RB Ollie Gordon II finishes with 103 rushing yards in Week 7 win
Packers defensive tackle Devonte Wyatt questionable to return after injury
Green Bay Packers defensive tackle Devonte Wyatt questionable to return after injury vs. Detroit Lions.
Lawmakers propose $11M fix to restore school sports and activities funding
by Katie Klingsporn, WyoFile Wyoming’s new school funding model added more than $250 million in state education funding, including for widely supported
Martin Short's Says His Countdown for Showbiz Sucess Was a Year With Social Work as Plan B
Oregon State gains ground in AP poll after bye week
The Beavers gained votes in the AP poll, but dropped in the coaches poll.
Clemson’s Loss to Virginia Tech Puts the Program in Flux
Clemson’s loss to Virginia Tech puts the program in flux heading into November. The Tigers now find themselves on the outside looking in on the ACC Championship race after being defeated 20-16 by the Hokies. Dabo Swinney’s team played well in many spots, especially in the third quarter. The complementary football Clemson displayed to start the …
‘Newlyweds’ Stars Debate the Meaning of ‘Dating’
And what it means for Jeanie and James in the series.
Chuba Hubbard has decent outing in Week 7
Panthers RB Chuba Hubbard finishes with 33 rushing yards and 27 receiving yards
New York Giants' Cam Skattebo Just Saved His Job
New York Giants running back Cam Skattebo saved his job against the Houston Texans.
U.S. measles cases more than double what they were last year as outbreak spreads
Pennsylvania is the worst hit state, with at least 1,338 cases of measles confirmed in 44 counties so far this year, according to the Pennsylvania Department of Health.
Kyler Murray throws for 150 yards, TD in Week 7
Minnesota Vikings quarterback Kyler Murray completed 14 of 24 passes for 150 yards, one touchdown and no interceptions in Week 7
Liverpool working towards deal for star; could reach €90m
Liverpool are reportedly in the mix for a very in-demand France star. They’re working towards a deal and it’s one that could cost €90m.Liverpool are weighing up their transfer targets for the up...
Frisco Muslims vote in Texas midterms marked by anti-Islam rhetoric
Texas politicians have campaigned on banning Shariah this cycle. Muslim voters are encouraging their fellow believers to get involved in politics.
How Pratt Proved Brewers Right in the World Series
Shrugging off an early error, rookie Cooper Pratt delivered a clutch game-winning hit, vindicating the Milwaukee Brewers long-term investment.
Yankees Social Media Spotlight: The MA kids head to MSG
Cam Schlittler and Ben Rice head to Madison Square Garden to watch the Knicks raise a banner.
Ex-Spur Jeremy Sochan becomes a Legend
The Dallas Legends used the top pick in Saturday's G League draft on Sochan, who will look to salvage an NBA career that has not gone as expected for the former lottery selection.
Erick All leaves Week 7 game early
Bengals TE Erick All ruled out after suffering a knee injury in Week 7
Michigan basketball gets reality check in exhibition loss vs Houston
Michigan writer Tony Garcia offers three observations from the Wolverines' 83-66 loss to Houston in its final exhibition.
Cardinals-Broncos Week 7 discussion thread
Talk about the Cardinals games with your friends at Revenge of the Birds.
Zen Browser is the Arc replacement I was looking for
Zen rips off all the best bits of Arc, but skips the AI and bloat.
Mid-Hudson Valley business calendar for the week of Oct. 26, 2026
Mid-Hudson Valley business calendar
New heist movie starring Pete Davidson to finally hit theaters in November
Billed as ”Point Break" meets “Fast and Furious,” Davidson will share the silver screen with Nicholas Hoult and Zoë Kravitz.
Cardinals vs. Broncos live updates, analysis, highlights, scoring
We have live updates of the Cardinals-Broncos game in Week 7. Keep up with pregame, in-game and postgame coverage.
NZ’s hidden chronic health burden is even bigger than we thought
New research reveals a major gap in how chronic illness is measured, with implications for planning and funding healthcare in New Zealand.
Christian McCaffrey able to return to Week 7 game
49ers RB Christian McCaffrey returns to Week 7 game after missing time with thigh issue
After arts festival, San Francisco's Mid-Market businesses look for signs of a turnaround
Cardinals Week 7 inactives
Cardinals announce seven inactives ahead of Week 7 game
“Business as usual” – PSG coach refuses to give his players an excuse after triple blow
PSG are missing some important players, but that’s not an excuse says manager Luis Enrique, who still expects the best.If you enjoy PSG Talk coverage and want to see more of it, add us as a preferre...
Defender turns striker and scores in Bayern win
Bayern Munich beat Freiburg 3-1 away from home to reclaim top spot in the Bundesliga on Sunday (25).Dayot Upamecano was one of the standout performers, scoring the opener with a move in which he playe...
Top Japanese Prospect Has His Eyes on the Dodgers
The Los Angeles Dodgers are the industry favorite to sign the best prospect in Japan, 18-year old pitcher Shoki Oda.
Cracking a smile regularly may be good not just for your mood but for your health
Reminding yourself to smile often can not only make more friendships but it can also make you feel better.
Inside 26-year-old’s club for million-dollar Chattanooga business owners
At 2nd American Restaurant on Thursday night, around 85 entrepreneurs who have scaled their businesses to at least $1 million in annual revenue sat to a family-style meal of beef cheek roast, airline chicken and the restaurant's signature bowl of mashed potatoes.
Vegas gives Ole Miss double digit spread against visiting Auburn
Despite the loss to Texas, Ole Miss is heavily favored against Auburn
The Times' top 25 high school football rankings
A look at the top 25 high school football teams in the Southland after Week 9.
Detectives seek information about business conducted with Piedmont Memorial Park Cemetery
Detectives are seeking information from anyone who has conducted business involving the cemetery since January 2019.
Blanche defends DOJ lawsuit blocking Alaska Senate results if Republican loses
Attorney General Todd Blanche defended the Justice Department's suit over Alaska's Senate race in an interview on CNN.
Knicks Have Clear Advantage Over Magic With Lopsided Injury Report
The New York Knicks look for their first win of the season.
COMMENTARY: Three reasons why Tennessee football imploded against South Carolina
Penalties, brain blips and a hangover conspire to doom Volunteers.
Lakers at Jazz: What to watch in first road game
Walker Kessler needed only two games to show how much he could change the Los Angeles Lakers' frontcourt.
Nico Williams publicly disavows his agent over Barcelona transfer claims
Barcelona’s long and drawn-out pursuit of Nico Williams has become one of the more familiar sagas of recent transfer windows.The Athletic Club winger ultimately opted to stay at San Mames, snubbing ...
Lady Gaga dancer reveals why he thinks she’ll succeed at motherhood
Lady Gaga’s backup dancer, who slid off stage mid-performance during last year’s Mayhem Ball world tour, is opening up about why he believes the singer will succeed at motherhood.
Hunter's Moon 2026: All About October's Full Moon And What To Expect Tonight
The title "Hunter's Moon" dates back generations, originating in the Northern Hemisphere because it typically follows the harvest season.
Senate rivals seek support from Alaska Native voters
The major candidates in Alaska’s U.S. Senate race are both casting themselves as strong voices on Alaska Native issues as they seek support from the key constituency ahead of the Nov. 3 election
'Sound of Music' star Julie Andrews spotted in rare Hamptons outing weeks after turning 91
Julie Andrews, 91, was photographed in the Hamptons wearing a purple raincoat and pink sunglasses in a rare public outing in the coastal city.
Jaylen Warren surpasses 100-yard mark in Week 7
Steelers RB Jaylen Warren rushes for at least 100 yards for third time this season
Broncos Place Linebacker, Running Back On Injured Reserve
The Denver Broncos have a fluid injury situation, with Tyler Badie and Jonah Elliss being placed on injured reserve.
Warren, Steelers stiff-arm Saints for 16-10 Paris win
Jaylen Warren had another big day and the Pittsburgh Steelers overcame some red-zone inefficiency to beat the New Orleans Saints.
Orlando Science Center hosts Halloween party
Adults can enjoy an open bar, laser shows, and more at the Orlando Science Center's Halloween After Dark on October 31.
Warriors honor Bay Area sports reporter Michael Wagaman
After Michael Wagaman passed away in early August, Dallas Braden took time to tribute him during his call of the Athletics’ game on NBC Sports Bay Area and California. Wagaman had covered Bay Area sports teams since 1996, including for the Associated Press, and freelanced for NBC Sports Bay Area and California at the time…
Sunday Puzzle: BRB
NPR's Ayesha Rascoe plays the puzzle along with Weekend Edition Puzzlemaster Will Shortz and WUOT listener Jordan Bogdan of Oak Ridge, Tennessee.
Lakers 1st-Round Draft Pick Floated as Trade Piece
The Los Angeles Lakers are off to a fast start. Could it be time to weigh trading away some young pieces to boost the rotation? The post Lakers 1st-Round Draft Pick Floated as Trade Piece appeared first on HEAVY.
Browns injury update: Is Denzel Ward playing against the Titans?
The Browns will enjoy the presence of their top cornerback in Week 7.
Lakers’ Injury Report Rules Out Two Players for Jazz Game
Is Walker Kessler available in his return to Utah?
Kansas at Duke: Exhibition OGT
Kansas basketball hopes to follow the football team with a win today. Yeah, this game doesn’t count, but any time you’re playing Duke you want to win. Plus, this exhibition game is a big enough deal that ESPN is broadcasting it live (probably because they know everyone else will be watching football. I’m probably going […]
One Of Steven Spielberg's Biggest Box Office Flops Is An Underrated Disney Movie
Steven Spielberg is one of the most prolific directors to still be working, and he's known for absolutely stunning films, but not every movie can be a hit.
Kings' Veterans Praise Rookie Acuff After 33-Point Showing
The Sacramento Kings are yet to get a win, but Darius Acuff Jr. looks like the high-octane guard that the franchise so desperately needs. Coming off a 33-point outburst, how will Acuff play against the Memphis Grizzlies?
3 comments | Progressive Democrats are closely watching four Senate...
Progressive Democrats are closely watching four Senate races in the upcoming midterm elections. Our politics reporter Kellen Browning explains why.
Week 7 inactives for Ravens
Baltimore declares five players inactive versus Cincinnati
Is having urine the color of Mountain Dew normal?
A Trump administration doctor says neon yellow urine is normal because of diets consisting entirely of meat and fermented foods. Here’s what experts say
Browns Week 7 inactives: Who's in, who's out?
The Browns are the healthiest they have been in some time as they take on the Titans in Week 7.
Trick-or-treaters descend on Callow Avenue for Calloween
Photos from Charleston Business District's annual Calloween event on Saturday, Oct. 24. ·
Chivu: “The boys gave everything right to the end”
Cristian Chivu wasn't the only one who couldn't bear to watch Zielinski's decisive penalty. The Inter coach bent over on the touchline, looking away as the midfielder stepped up to take it. When the b...
Baltimore Ravens vs. Cleveland Bengals Week 6 game discussion
Join the discussion about the Ravens’ Week 7 matchup with the Bengals!
How Braves should handle $42 million Jurickson Profar situation
This could be one solution for the Braves.
ESMO: Roche touts ‘convincing’ phase 3 KRAS data after win over rivals
Roche has shed more light on its investigational KRAS G12C inhibitor's phase 3 victory over Amgen’s Lumakras and Bristol Myers Squibb’s Krazati. The open-label Krascendo 1 trial enrolled 338 people with previously treated KRAS G12C-mutated non-small cell lung cancer (NSCLC). Patients who had already received a KRAS G12C inhibitor or pan-KRAS/RAS inhibitor were excluded from the trial. Participants received either divarasib once daily, Lumakras once daily or Krazati twice daily. Roche announced back in July that divarasib had demonstrated statistically significant improvements in progression-free survival (PFS) and overall survival (OS), meeting the trial’s primary and key secondary endpoints. But the Swiss pharma had been holding back the detailed data until now. At the European Society for Medical Oncology (ESMO) Congress in Madrid, Roche revealed that median OS for the 167 patients who received divarasib was 17.7 months, compared to 12 months for the 171 patients who received Lumakras or Krazati. The benefit was similarly clear when it came to median PFS, which stood at 9.8 months versus 5.7 months, respectively. A total of 44% of patients receiving divarasib were alive without disease progression at one year, compared to 24% of the control group, according to Roche’s presentation. It was a similar story for the objective response rate, which came in at 58% for divarasib versus 32% for the control group, while median duration of response was 11.9 months versus 6.9 months. Stefan Frings, M.D., Ph.D., deputy chief medical officer at Roche Pharma, told Fierce that the data made for a “very comprehensive, strong package, which should be convincing to health authorities.” “It’s an important advance for patients with lung cancer,” Frings said in an interview at a Madrid hotel during the conference. “It's a second-line setting, and patients who receive divarasib benefit compared to the current first-generation KRAS G12C inhibitors by having far longer overall survival,” he continued. “They live longer. They have better progression-free survival, better response rates, and with a safety profile which is—if [anything]—even better,” he said. According to Roche, 4.8% of patients receiving divarasib discontinued treatment due to treatment-related adverse events, compared to 11.7% in the control group. Serious treatment-related adverse events were also less common with divarasib, at 7.8% versus 15.2%. Roche’s confidence in divarasib had been building even before this phase 3 success. The candidate had already shown better potency and selectivity than the incumbent KRAS G12C inhibitors Krazati and Lumakras in preclinical tests. After cross-trial comparisons suggested that the edge translated into better clinical outcomes, Roche axed a study comparing divarasib to the chemotherapy docetaxel and went toe-to-toe with Lumakras and Krazati. “We designed the drug on purpose with higher potency and better selectivity,” Frings explained. “So, based on preclinical models, we clearly knew it would be superior to the first generation.” “It’s honestly not so frequent that pharma companies go head-to-head,” he added. “But if you want to make a point, if you want to convince payers, prescribers and patients … then a head-to-head win is rather rewarding.” While Amgen and BMS reached the regulatory finish line first for KRAS G12C-mutated, locally advanced or metastatic NSCLC in 2021 and 2022, respectively, they have struggled to capitalize on their head start. Krazati brought in $55 million for BMS in the second quarter, while Lumakras delivered $111 million to Amgen. For its part, Roche is aiming for peak divarasib sales of 1 billion to 2 billion Swiss francs ($1.2 billion to $2.5 billion), according to Frings. The Big Pharma is currently recruiting patients into a phase 3 trial comparing divarasib plus Keytruda against Keytruda plus chemotherapy in previously untreated advanced or metastatic nonsquamous KRAS G12C-mutated NSCLC. Roche has previously suggested that sales in metastatic disease would account for most of the forecast. Frings was tight-lipped on the exact timeline for a regulatory filing but said the Swiss pharma is “certainly keen to get this to as many patients as possible around the world.” Roche has more RAS drugs coming up behind divarasib. The pharma has already launched phase 1 trials of a pan-RAS inhibitor called RG6505 and a KRAS G12D inhibitor dubbed RG6620 in solid tumors. Roche’s partner Chugai Pharmaceutical is also testing a pan-KRAS inhibitor called AUBE00. Roche has made a “deliberate effort” to test a range of RAS drugs, Frings said. “If you have many rare mutations and you are scrambling to find sufficient patients, a pan-RAS inhibitor makes a lot of sense,” he explained.
California Politics 360 full episode | Clash over voter rolls heads to court
On Tuesday, one week before the election, a federal judge will determine the next steps.
Robinson, Baker have tough talk about the offense
Robinson, Baker have tough talk about the offense
Their friend died of cervical cancer in 2020. Now, they advocate for women’s health in N.S.
Following the death of their close friend from cervical cancer in 2020, two women in Nova Scotia were left wondering how things might have been different had she been diagnosed earlier. Six years later, they have raised over $4 million to improve technology and infrastructure for women's health.
MCHD: Several people treated at local emergency rooms for bat bites in Baldwin County
The Mobile County Health Department says the patients were bitten at different residences in Baldwin County.
GO Health asks families to be lead-aware
BATAVIA — Area health departments are encouraging families to get the facts and get their children and homes tested for National Lead Poisoning Prevention Week.
What Chelsea Did Wrong vs Tottenham
After a stellar run following the international break, things came crashing down for Chelsea as they lost 2-0 to Tottenham Hotspur at the weekend. This marked an extremely rare defeat at Stamford Bridge to the Lilywhites, a crack in a strong record of home wins that has left fans reeling. In this, we will be …
Aaron Rodgers passes Peyton Manning on all-time touchdowns list
Aaron Rodgers surpasses Peyton Manning in all-time touchdown passes.
University of Rochester Medicine Home Healthcare holds inaugural Hospice 5K
13WHAM ABC Rochester provides local news, weather forecasts, traffic updates, health reports, notices of events and items of interest in the community, local sports and entertainment programming for Rochester and nearby towns and communities including Greece, Victor, Pittsford, Penfield, Henrietta, Webster, Irondequoit, Fairport, Chili, Gates, Rush, Wheatland, Canandaigua, Farmington, Spencerport and Hilton.
World's Fastest Lawnmower Company Is Officially Going Out Of Business
Dixie Chopper made the world's raddest lawnmowers for almost half a century, but its story is now coming to an end.
Grading Iowa Football's Loss To Minnesota
This may have been Iowa's worst quarterback performance since the dreadful 2023 season.
Mavericks 'Very, Very Confident' in Rookie PG Behind Kyrie Irving
Spanish sensation Sergio de Larrea shined with 21 points against San Antonio, proving he can anchor the rotation while Dallas carefully manages Kyrie Irving’s heavy workload.