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America’s long-haul truckers were already struggling. Then came $5 diesel
Diesel, the largest day-to-day expense in trucking, has jumped in price since the start of the Iran war. That’s hurting the trucking industry, particularly small fleet owners.
A nutrition scientist shared 3 food swaps for heart-healthy meals
Professor Sarah Berry, a nutrition scientist who specializes in cardiovascular disease, said getting the basics right can go a long way toward supporting our heart health.
On Canada's tariff frontline, business stalls over US trade deal jitters
WINDSOR, Ontario, March 28 (Reuters) - Windsor-based FASTSIGNS, a Canadian company that designs and installs custom business signs and graphics, last year endured its toughest year since the pandemic as orders from its core automotive clients dried up. A new project launch this year brought some relief, but the company says customers are demanding longer payment terms, placing smaller orders, and bargaining harder on prices due to uncertainty tied to the United States-Mexico-Canada Agreement,
Is Iran a Political Problem for Trump? Tell Me How Long the War Lasts.
Historically, quagmire abroad and high prices at home are the ingredients of a failed presidency.
Larry Price, former UH football coach and longtime broadcaster, dies
Larry Price, a one-of-a-kind homegrown talent who helped shape University of Hawaii football and local sports media for decades, has died.
Lakers’ PA announcer Lawrence Tanter misses game because of ‘health matter’
When the Lakers hosted the Nets on Friday, there was an iconic deep voice missing inside of Crypto.com Arena. Longtime franchise public address announcer Lawrence Tanter wasn’t in attendance for...
Braiding science, stories and indigeneity with Robin Wall Kimmerer’s ReadUP talk
Half an hour before the start, BC Aud was already overflowing. Attendees pressed shoulder to shoulder along stairways to hear Robin Wall Kimmerer, an author and environmental activist. Click the link to read the recap of her events on campus.
Cottage Grove board advances sports complex project with permit approvals
The board recently approved rezoning for the property near Gaston Road along with a conditional use permit, allowing the proposed sports facility and outdoor amenities.
Riverhead may revive condemnation of L.I. Science Center building
Riverhead officials say time may be up for the long-delayed science center project, signaling readiness to revive condemnation of the Main Street building.
Mystery medical episode that left astronaut unable to speak shows one of NASA's biggest risks as moon missions ramp up
Veteran astronaut Michael Fincke's sudden medical emergency aboard the ISS is a stark reminder that, as NASA pushes toward long-term lunar missions, astronaut health remains one of spaceflight's biggest unknowns.
Source within Banks business community speaks out about impact of chaos on 'best sales day of the year'
One source with The Banks business community, who wished to not be identified, told us that the early shutdown due to massive crowds and violence greatly impacted the businesses along The Banks.
Business Lookahead: Gauging the war's impact
STORY: From a worrying drop in stocks to a surge in energy prices from the war in the Middle East to key data on jobs and trade, these are the stories to watch in business and finance in the coming week. ::Look Ahead::War impactThe first quarter is ending with financial markets at the mercy of geopolitics.The Iran war has wiped roughly $7 trillion off global stocks since it erupted.With oil prices up nearly 70% year to date, suddenly interest rates are heading up, rather than down, and energy-hungry AI does not look like such a slam-dunk anymore.Meanwhile, gold has plunged 16% after being nearly unstoppable since the start of 2025.We’ll see whether markets roll on or rollover as the second quarter begins.::Job growth in focusThe U.S. jobs report for March comes out Friday.It will offer a crucial view into the economy's health as investors gauge fallout from the energy price surge.Monthly payrolls are seen rising by 48,000, according to a Reuters poll. February's surprisingly weak report caught Wall Street off guard, showing nonfarm payrolls fell by 92,000 while the unemployment rate increased to 4.4%.Uncertainty over the Iran war is also clouding the economic forecasts for the Federal Reserve, with Wall Street pulling back on expectations for U.S. interest rate cuts this year as the oil price surge fuels concerns about rising inflation.Other U.S. data in the coming week includes retail sales for February and reports on manufacturing and services activity.::Chip checkSouth Korea releases its trade data for March on Wednesday.It will provide an early indicator of how the global economy is holding up in the face of the war and the resulting shock to energy prices. Korea's export-heavy economy is a bellwether for global trade and one of the first to report data from the previous month.Its manufacturing fortunes are of even greater interest than usual, not just because of its dependence on Middle Eastern energy imports, but also because its world-leading DRAM chips are of critical importance to the AI sector and currently in short supply too. ::Inflation assessmentAnd flash euro zone inflation for March is due on Tuesday. After long hovering around the 2% mark, higher energy prices are now expected to push headline inflation up, as they did in 2022. The question is, how large and sustained any jump in inflation might be.Early data is not painting a pretty picture. Private sector growth in the euro zone slowed sharply in March, with input costs rising to their highest in more than three years and supply chains being significantly disrupted.Money markets are now heavily pricing in a rate hike which was almost unthinkable before the Iran war.
For service disabled vet, a long journey in cannabis business paying off
One of New York’s few cannabis businesses owned by a service disabled veteran is celebrating a milestone.
Pro-Iranian group claims credit for hack of FBI director's personal account
The group Handala posted online what appear to be years-old photographs of Patel, along with a work resume and other personal documents
Riverhead may seize L.I. Science Center property amid delays
The Riverhead Town Board said if the Long Island Science Center doesn't fulfill its expansion plans, they may proceed with eminent domain.
Apple has finally discontinued the Mac Pro desktop after years of fitful effort
M2 Ultra Mac Pro is no longer for sale, and Apple says no replacement is planned.
Mac Pro Discontinued: Reflecting on 20 Years of Apple's Desktop Tower
Apple this week announced that it has discontinued the Mac Pro, with new configurations no longer available and no further models planned. Below, we reflect on nearly two decades of the Mac Pro. 2006 to 2013 In August 2006, Apple introduced the original Mac Pro, which was an Intel-based follow-up to the PowerPC-based Power Mac G5 that debuted a few years earlier. Mac Pro was the final Mac model to transition from PowerPC to Intel processors.
Vanderbilt Lung Transplant Program sets new record
The Vanderbilt Transplant Center is now the second largest lung transplant center in the United States by volume, with 149 lung transplants in 2025, the most ever in one year at Vanderbilt Health. The Vanderbilt Lung Transplant Program leads the nation in organ preservation and regeneration and is among the best in long-term outcomes, demonstrating the success of the interdisciplinary team in caring for these complex patients. Several features make the program unique in the United States, said Konrad Hoetzenecker, MD, PhD, professor of Thoracic Surgery and surgical director of the Vanderbilt Lung Transplant Program. Vanderbilt serves as a “second opinion center” and accepts most complex candidates that are turned down by other centers due to increased perioperative risk. This includes patients over 70 years old, patients requiring combined procedures with their transplant, multiorgan transplantations and sensitized patients (individuals who have pre-formed anti-HLA antibodies who are at higher risk for complications). The expertise and excellent outcomes have attracted patients far beyond the borders of Tennessee; almost half of Vanderbilt Health’s lung transplant recipients come from out of state. “Another unique feature is our minimally invasive transplant program,” Hoetzenecker said. “By using distinct surgical instruments and techniques, the incisions can be kept as small as 7 to 8 centimeters, which results in better healing, less pain and faster recovery. “This minimally invasive approach is embedded in an Enhanced Recovery After Surgery (ERAS) protocol, a multimodal, evidence-based perioperative care pathway designed to reduce surgical stress, minimize complications and speed up recovery. Our unique ERAS protocol, by a dedicated interdisciplinary approach, aims to improve recovery after lung transplant and reduce ICU and hospital stay.” The lung transplant program recently celebrated a milestone — 1,000 lung transplants since the program began in 1990. “This significant achievement reflects the concerted effort of a multidisciplinary collaboration by the Departments of Thoracic Surgery, Medicine, Anesthesiology and Critical Care,” said David Erasmus, MD, associate professor of Medicine and medical director of Vanderbilt Lung Transplant. Lung transplants have been attempted since the 1960s, but they were largely unsuccessful until the 1980s, when surgical techniques were refined and new antirejection drugs proved effective. Patient outcomes steadily improved from the 1990s to the present. Vanderbilt’s fourth lung transplant recipient in 1990, Pam Everett, is the longest-living, single-lung transplant known in the world, recently celebrating 35 years since her transplant. The Vanderbilt Lung Transplant surgical team is led by Hoetzenecker and Caitlin Demarest, MD, PhD, the surgical director and associate surgical director of the Vanderbilt Lung Transplant program. Erasmus is the medical director of Vanderbilt Lung Transplant along with Anil Trindade, MD, associate medical director and associate professor of Medicine.
The Oscars are leaving Hollywood in 2029, ending long run at Dolby Theatre
The Academy Awards will move from the Dolby Theatre, their home for nearly a quarter century, to L.A. Live in downtown Los Angeles
The Louisiana purchase: Will Wade saga shows what college sports no longer pretends to be
The real reckoning finally came. Will Wade’s hasty exit is a Flagrant 1 against fan morale and not just in Raleigh.
NTT Data CEO on managing business in the Middle East amid on-going conflict
Abhijit Dubey CEO of NTT Data says rising energy prices so far have had little impact on their data center businesses due to the long-term contracts and their ability to pass on costs to customers.
University of New England taps health care exec as commencement speaker
Daniel P. McCormack, CEO of Spectrum Healthcare Partners, is a long time member of the school's board of trustees.
I canceled my flight for a 20-hour Amtrak ride amid TSA airport chaos
TSA chaos and long airport lines pushed me to cancel my flight and take a 20-hour Amtrak ride instead. Here's why I'd do it again.
50 Years of Environmental Data Can Predict Health and Strandings of Sea Lions Pups in California
For more than 50 years, NOAA Fisheries has conducted vital research on seal and sea lion populations at a remote research station on San Miguel Island, California. The long-term data set provides clues to help us understand what environmental conditions lead to malnourished California sea lion pups and increased stranding levels. This information is important for managing their populations and helping rehabilitation centers prepare for periods when sea lion pup strandings may be elevated.
Longtime local business sold. Here's what to know about the sale
When the owners of this central Illinois business decided to sell, they were looking for a company that shared their core values.
For Trump, a Deadline Isn’t Always a Deadline | WSJ Politics Newsletter for March 27
Plus, the Senate approves funding for most of DHS, moving to end long airport-security lines
Health-Care Costs Are Forcing Terrible Trade-Offs
Earlier this month, as I waited to pick up a prescription at my local CVS, I watched a man leave without his elderly father’s medication. The pharmacist had tried several tricks to lower the cost. It wasn’t enough. When the man heard the bottom line, he stuffed his hands in his pockets and, after a long, awkward silence, walked away.
See United's new Polaris business class with doors and a 'Studio'
United's new Polaris business class got a long-awaited facelift with sliding doors. Though the doors will remain open for now, pending certification.
New Resident Evil Requiem patch adds highly-anticipated photo mode feature
The powers that be at Capcom have released an update for Resident Evil Requiem, which along with other fixes and such also adds photo mode.
Long Island Science Center faces renewed eminent domain threat from Riverhead
Town board members, exasperated at the lack of progress on renovations to the science center's Main Street facility, said they would give its leaders one more chance to make their pitch.
Hydrogen-powered business jet edges closer to certification
If you've ever hankered after a hydrogen-powered business jet, your wait might not be much longer. French aerospace startup Beyond Aero's BYA-I One aircraft has completed its Preliminary Design Review, pushing it along the path to certification.
DHS shutdown breakthrough comes at cost for Republicans as funding fights nears end
The Senate advanced a DHS shutdown deal without ICE or CBP funding, as Republicans plan to use reconciliation to secure immigration enforcement funding long-term.
Long Covid vs UConn’s GA health insurance
UConn’s proposed increases to the health insurance premiums would contribute to health disparities, and make healthcare even less accessible than it is now.
Preserving Detroit History: City awards grants to 30 long-standing local businesses
On Thursday evening, 30 Detroit legacy businesses were awarded a grant by the Detroit Economic Growth Corporation and the mayor's office.
How Democrats Can Defeat Trump’s Identity Politics
Author Justin Gest says that appealing to voters’ sense of belonging and identity is essential and can’t be done with economic policy alone.
Nacogdoches Pro Rodeo kicks off with trick riding, family entertainment
The annual Nacogdoches Pro Rodeo kicked off Friday night at the Nacogdoches Civic and Expo Center, bringing professional riders from across the country along with family entertainment and arena performances.
Trump's signature to appear on future currency, Treasury announces
The move breaks with longstanding precedent. For more than a century, US banknotes carried the signatures of Treasury officials, not the president.
D.H.S. Funding Lapse Leads to Longest Partial Shutdown in History
If the shutdown continues after this weekend, it will be longer than any previous shutdown, partial or full.
HOMETOWN ENTERTAINMENT: Lots of events across southwest and central Virginia this weekend
Grandin Chillage returns Friday to Roanoke with live music and food, along with the long tradition of the MDA Car Show in Salem
Long-time UTSA supporter, Harvey E. Najim, helps strengthen pediatric health workforce
SAN ANTONIO – UT Health San Antonio, the academic health center of UTSA is expecting to help pediatric-focused professionals in dentistry, medicine and nursing
Exclusive: Occidental's Hollub, US oil's most powerful woman, prepares to hand over reins, sources say
Vicki Hollub is preparing to retire as chief executive of Occidental Petroleum , after her decade-long stewardship of the U.S. oil and gas company that made her one of the most powerful women in a male-dominated industry, sources familiar with the matter told Reuters.
18 million-year-old fossils of ape found in Africa, but in an unexpected place
The ancestor of apes was long thought to come from East Africa, but newly discovered fossils in Egypt may prompt a rethink.
Comedy showcase to feature new and established talent
MIZEL ARTS AND CULTURE CENTER Denver News: A host of emerging comedians will perform along with Denver native and nationally recognized comic Noah Gardenswartz when the Mizel Arts and Culture Center hosts The Tight Five: Standup Comedy Showcase. The up-and-comers take the stage first, offering their “tight five” — five minutes of original material developed during an eight-week comedy writing program that […]
Scientists Successfully Unfroze Part of a Mouse Brain—and It Still Worked
We’re a long way from reviving a frozen human, but new research yields insight.
Penn State Schuylkill sponsors Business Executive Forum with provost
Penn State Schuylkill recently sponsored the Schuylkill Chamber of Commerce’s first Business Executive Forum of 2026 on March 18, marking the 10th year the campus has hosted the event and brought together more than 100 business and community leaders, along with local and state legislators and several University leaders, for a discussion on leadership and the future of work.
Does red-light therapy work? What the research says
People are buying helmets, face masks, vests and beds that emit long-wavelength light. Beneath the hype, there is some interesting biology.
Florida congresswoman faces a rare public hearing on ethics charges. Threat of expulsion vote looms
The House Ethics Committee is holding a rare public hearing into alleged ethics violations by Sheila Cherfilus-McCormick. The hearing Thursday pushes into the open a yearslong investigation into how...
Ahead of Atlanta visit, Cory Booker casts Georgia as key political battleground
U.S. Sen. Cory Booker heads to Atlanta on Friday to appear alongside U.S. Sen. Raphael Warnock at the First Baptist Church of Decatur.
Flutter Entertainment (NYSE:FLUT) Valuation After Prolonged Share Price Weakness And Undervaluation Debate
Why Flutter Entertainment is on investors’ radar today Flutter Entertainment (NYSE:FLUT) has drawn attention after a period of weak share performance, with the stock showing negative returns over the past day, week, month, past three months, year to date, and past year. With the share price at US$103.40 and a market value of about US$18.9b, investors are weighing these declines against the company’s scale, global footprint, and recent revenue and net income figures. See our latest analysis...
South Korea’s Kakao Entertainment appoints JungHee Ko as Co-CEO alongside Joseph Chang in
Ko takes on an additional role as Chief Platform Officer, overseeing a newly created unit responsible for Kakao Entertainment’s platform services…
The Best Time to Eat High-Fiber Foods If You Want to Poop Tomorrow, According to Dietitians
Learn the best time to eat fiber to help you poop the next day, plus which foods work fastest and how long fiber takes to improve digestion.
‘Science Friday’ Host Ira Flatow to Share Health and Wellness Discoveries on April 23
Are ultramarathoners built differently from the rest of us? What can Greenland sharks teach us about aging eyes? As the longtime host of the popular public radio program and podcast Science Friday, Ira Flatow explores questions like these during engaging discussions on topics ranging from science and technology to health, space and the environment.
Mark Nordenberg to step down from his leadership roles with the Institute of Politics and Dick Thornburgh Forum
The chancellor emeritus, who has long been a driving force behind the wide-ranging civic initiatives, will also serve as the University’s 2026 spring commencement speaker.
Good Morning, Nashville! Talking Immigration Data Politics at Vanderbilt University
After a busy day on Capitol Hill yesterday, I landed in Nashville, Tennessee, last night for an exciting two days on campus at Vanderbilt University. Carwil Bjork-James, an anthropologist whose creative use of database construction to support critical scholarship resonates strongly with my own work, generously invited me to give a talk today about the politics of immigration data and to join a Wikipedia edit-a-thon tomorrow on the topic of immigrant detention. I encourage you to check out Carwil’s database project “Ultimate Consequences” about political deaths in Bolivia after 1982, and his book The Sovereign Street: Making Revolution in Urban Bolivia. My talk today is titled “Untangling the Messy Politics of Immigrant Detention Data.” I’ll focus on how immigrant detention data (not just detention centers themselves) become sites of controversy—from the collection and classification choices that shape what we can know, to the strategic withholding and distortion of data for political ends. Drawing on research spanning multiple administrations, I’ll trace how current data controversies in the second Trump administration connect to long-standing tensions in how we measure, interpret, and communicate about immigration. My goal is to move beyond simple partisan narratives and offer a practical guide for anyone working with immigration data to explore both the pitfalls to avoid and the creative opportunities for more transparent, rigorous public communication about immigration realities. If you are on campus, please stop by. Tomorrow I will join Carwil and Vanderbilt students for a Wikipedia Edit-a-Thon to edit and update Wikipedia entries related to immigrant detention with the latest robust information and data. This event is designed to orient participants into how to edit on Wikipedia, provide them with data-driven starter templates on detention facilities, and allow each person to produce an initial article on one element of the network of ICE facilities or one death in custody this year. The workshop is also a demonstration of how to use open data sources to build public knowledge—something I am deeply passionate about. Thank you to Vanderbilt University, the Spatial Histories series, and Carwil for hosting me. I would love to be a part of conversations and workshops related to immigration data on your campus. Students are really eager these days to have informed, critical, and data-driven explorations of our current immigration system. Reach out anytime if you want to discuss the possibility of bringing me to your campus. Subscribe
Meet Ran II: After Losing A Sub Under The “Doomsday Glacier,” Scientists Have A Smarter Successor
Ran is dead, long live Ran II.
How a Healthy Mind-Set Influences Longevity
A few qualities, including a sense of purpose, seem to have real benefits — especially as you age.
iOS 26.4—Update Now Warning Issued To All iPhone Users
Apple has released iOS 26.4, along with a warning to update your iPhone now, because it contains a whopping 37 fixes. Here's what you need to know.
Pokémon Champions Plans To Keep The Stadium Lights On For A Very Long Time
"Basically forever"
'No good choice' for GPs as child mental health demand 'skyrockets'
GP says long waits for support mean some doctors feel forced to prescribe medication outside of guidelines.
Wall Street pros are nervous about Iran and warn about complacency
A prolonged conflict could hit growth, lift inflation, and jolt equities.
Paul George speaks after impressive return from suspension
George had four steals to go along with 28 points.
Derek Sant’Angelo named fellow of the American Association for the Adv
This highly selective honor is in recognition of the VCU professor’s career-long contributions to the field of T cell immunology.
Scientists open a million-year-old time capsule beneath New Zealand
Deep inside a cave, scientists uncovered fossils from 16 species, including a newfound kākāpō ancestor that may have been able to fly. These remains reveal that New Zealand’s ecosystems were constantly disrupted by volcanic eruptions and rapid climate shifts. Long before humans, waves of extinction and replacement reshaped the islands’ wildlife. It’s a rare window into a missing chapter of natural history.
Reality TV thrives on messy people — but the Taylor Frankie Paul backlash reveals when audiences finally draw the line
Reality TV thrives on turning personal controversy into entertainment, but Taylor Frankie Paul’s backlash shows the line is crossed when audiences can no longer separate what they’re watching from rea...
2025-26 Sweet 16 Betting Report: Swing in Futures Liability Impacting Books
The books no longer need who they thought they needed when the Tournament began. Patrick Everson has the scoop.
Florida Democrats flipped 2 legislative seats Tuesday. Is it a harbinger of trouble for the long dominant GOP?
Wins in districts previously carried by Donald Trump have Democrats bullish about the future.
Melania Trump shares the spotlight with a robot at an education and technology event
Melania Trump and the humanoid walked slowly side by side along the red carpet from the opposite end of a White House hallway.
NYC Health + Hospitals Honors Nursing Home Resident Centenarian Carmen Augustin at Age 112 - NYC Health + Hospitals
NYC Health + Hospitals/Coler honored Carmen Augustin marking her 112th birthday celebration. Augustin is the oldest long-term care resident across the
Students ‘Surge’ with fun at local entertainment center
Have you ever wanted to visit an arcade, a restaurant and a bowling alley all in one place? Surge Entertainment by Drew Brees combines all three in same building, along with more activities including laser tag and sports simulators. While the venue offers variety, its attempt to do everything at once leaves certain areas underdeveloped,...
Randolph College to host Science Festival, in celebration of all things Science
What started as a kids festival has grown into a very popular week-long event.
Another co-founder is exiting Elon Musk's xAI
Manuel Kroiss is one of 11 engineers who helped launch xAI alongside Elon Musk in 2023. The number of cofounder departures now sits at 10.
Decoding the Visual World
Learn how NSF's long-standing investments helped computers learn to identify and interpret images, advancing technologies now integral to people's daily lives.
Massachusetts hospital EDs have a mental health 'boarding' problem
Such long waits are expensive and unhelpful for patients experiencing psychiatric crises, in addition to tying up in-demand hospital beds, the report said.
Aspen Medical Care joins Aspen Valley Health Primary Care
Aspen Valley Health has announced that Aspen Medical Care, a long-standing independent primary care practice serving the Roaring Fork Valley since 1997, will become part of its Primary Care network.
Steve Mosko Joins Board Of Radial Entertainment
Steve Mosko, former longtime Sony Pictures Entertainment television chief, and CEO of Village Roadshow, joined the board of Radial Entertainment.
Can Lifestyle Changes Over a Lifetime Protect Brain Health?
University of Miami researchers link long‑term exercise, diet, and social engagement to better cognition with aging.
Google launches Lyria 3 Pro music generation model
Google is launching Lyria 3 Pro, an upgraded music model that generates longer, more customizable tracks, as it expands AI music tools across Gemini, enterprise products, and other services.
Sky River's Five-Story Parking Garage Opens, Advancing Entertainment and Tribal Development in Elk Grove
Sky River Casino has now opened its new five‑story parking structure, an investment that strengthens Wilton Rancheria’s long‑term economic development strategy that is firmly rooted in the Tribe’s resilience and vision for future generations. Featuring 1,600 parking stalls across 681,263 square feet, the structure seamlessly connects with the recently expanded 20,000‑square‑foot gaming floor through an […]
iOS 26.4 has fixes for 35+ security issues on iPhone, details here
iOS 26.4 launched yesterday, and alongside new features, it brings over 35 key security fixes for your iPhone per Apple’s notes.
Partial government shutdown continues with long lines at airports
The long lines at airports and the DHS shutdown continue, but could a deal by on the horizon?
Glyphosate: A story of science, risk, and nuance
In the summer of 2014, a California groundskeeper named Dewayne Johnson started noticing patches of raw, weeping skin spreading across his body. He had spent years applying Roundup, Monsanto’s glyphosate-based herbicide, for a school district, sometimes drenched in it when equipment malfunctioned. By 2014, he had a diagnosis: non-Hodgkin’s lymphoma. In 2018, a jury awarded him $289 million in damages, later reduced on appeal. Tens of thousands of lawsuits followed. The story hasn’t quieted down. It’s all over the internet, swinging between “this will kill you, buy organic” and “relax, you’re fear-mongering.” Some of that recent chatter stems from an Executive Order protecting glyphosate and its production, which set off intense infighting within the MAHA movement. Some of it reflects a deeper truth: Americans genuinely care about harmful chemicals in their environment (see poll below). And the conversation isn’t going anywhere, with a Supreme Court case involving Monsanto set for this April. Glyphosate (the active ingredient in Roundup) is one of the most widely used herbicides in the world. But does glyphosate cause cancer? And how much exposure is actually risky? With so much mistrust in institutions and corporations (and some genuine conflicts of interest), making sense of the actual scientific evidence is genuinely hard. Here is a translation of what the scientific evidence actually says. Does glyphosate cause harm? Glyphosate is an herbicide that kills most plants it contacts rather than targeting specific species. It works by blocking an enzyme pathway (EPSPS) that plants and many microorganisms need to produce essential amino acids. Without those amino acids, the plant can’t grow and dies. Glyphosate was first developed by Monsanto in the 1970s and became ubiquitous after the company introduced “Roundup Ready” crops in the 1990s. In 2024, Bayer removed glyphosate from residential Roundup-branded products due to litigation pressure. But today it is still the most widely used herbicide in the world. Farmers also discovered they could spray it directly on crops like oats, lentils, beans, and peas just before harvest to dry them out faster and make harvesting easier. Because of its widespread use, it’s obviously really important to understand if it’s harmful to humans. The key principle: The dose makes the poison The most important concept in toxicology is that “the dose makes the poison.” Sixteenth-century physician Paracelsus articulated what remains the foundational principle of toxicology: sola dosis facit venenum. Water will kill you if you drink enough of it. Aspirin saves lives at 81 milligrams and causes internal bleeding at higher chronic doses. So, at what dose is glyphosate poisonous? The LD50 in rats (the dose that kills half the test animals) is around 5,600 mg/kg body weight. Table salt is roughly 3,000 mg/kg. By that classic measure, glyphosate is less acutely toxic than salt. But some people are exposed to a lot of glyphosate through their work. And among the general public, there are many questions about low-dose, cumulative exposure from multiple sources over long periods. Does glyphosate cause health problems? Cancer Correlation maps are striking, with one analysis finding that 60% of counties that spray the most glyphosate have non-Hodgkin’s lymphoma rates above the national average. But correlation alone doesn’t establish cause, which is why animal and human studies matter. In animals: Rat studies are typically what most fear is rooted in, but most people don’t know the study details on the dosage given to rats. A pooled analysis of the 13 most rigorous rat studies found evidence that very high doses, around 55,000 times greater than typical food residue exposure, can cause certain cancers. In humans: One of the strongest studies followed 55,000 herbicide users over 20 years and found no overall increased cancer risk. There was one signal: among those with the highest use, rates of acute myeloid leukemia (AML) appeared elevated. A broader meta-analysis of 18 human studies also found no overall cancer risk, though a separate meta-analysis focused specifically on non-Hodgkin lymphoma found that people with high cumulative glyphosate exposure faced a 41% higher relative risk compared to those with low or no exposure. These human studies are observational studies (randomized controlled trials would be unethical), and meta-analyses are only as reliable as the studies they pool. But the story seems consistent: at very high exposure levels, there may be some cancer risk. But that’s about as far as the science currently takes us. Emerging research: gut and reproductive health Gut: Because glyphosate targets a pathway that exists in some gut bacteria, scientists have questioned whether it could affect the microbiome. In mice, a 2023 University of Iowa study found that glyphosate altered gut bacterial composition and raised markers of intestinal inflammation. A 2024 systematic review found similar patterns: disrupted gut bacteria and problems with the mucus layer that protects the intestinal wall in mice. Whether this translates to humans is an open question. The human gut is highly variable and resistant, and we don't yet have strong studies confirming the same effects in people. Reproductive health: Animal studies have found that glyphosate-based herbicides can interfere with reproductive hormones, including disrupting egg cell development in mice and reducing the number of eggs available in sheep’s ovaries. However, the doses used in these experiments were high, so it’s not yet clear whether the same effects would occur in humans. On the human side, a 2021 pilot study led by Mount Sinai researchers tested urine samples from pregnant women across the U.S. and found glyphosate in 95% of them. The study also found a possible connection between higher glyphosate exposure during pregnancy and a subtle physical difference measured in female newborns. That said, some connections weren’t statistically reliable and this was a small study. The researchers themselves said more and larger studies are needed before drawing firm conclusions. What do regulators say about glyphosate safety? In 2015, the International Agency for Research on Cancer (IARC), part of the World Health Organization, classified glyphosate as "probably carcinogenic to humans" (Group 2A). The classification is worth taking seriously. But, there’s an important distinction: IARC classifies hazard, meaning the potential to cause harm under some conditions. It does not assess risk, which accounts for actual exposure levels and the real-world probability of harm. The U.S. EPA, the European Food Safety Authority, Health Canada, and regulatory agencies in Australia and Japan have all concluded that glyphosate is “unlikely to be carcinogenic to humans” at realistic exposure levels. They’re asking a different question: given how much of this people actually encounter, what is the probability of harm? Your actual exposure is what determines your actual risk. What does glyphosate mean for your daily life? At the grocery store: Food residues are small. The EPA’s acceptable daily intake is 1.75 mg/kg of body weight per day. To hit that threshold from oatmeal alone, a 150-pound adult would need to eat roughly 50 pounds of oats every day. But this calculation addresses only one pathway (food), and we don’t yet have robust tools to measure people’s actual total exposure. If reducing exposure matters to you, organic certification prohibits synthetic herbicides, and organic oat products generally test at lower or undetectable levels. Either way, a diet rich in whole grains, conventional or organic, is far better for your health than one that omits them out of fear of residues. On the farm: Occupational exposure is orders of magnitude higher than consumer exposure. Farmers and farm workers who mix, load, and apply glyphosate-based herbicides, especially without protective equipment, face meaningfully different risk profiles. Proper PPE isn’t optional. Integrated weed management strategies that rotate chemical modes of action are also worth taking seriously, both for health and for long-term effectiveness. If you live near a farm: Spray drift is real. Concentrations near field edges can spike during and after application, particularly on windy days. This is an area where I think public health could really step up and empower rural communities with buffer zones, rather than placing the onus on individuals. But for now, knowing your local agricultural calendar and keeping windows closed during application are the first steps. Bottom line Dewayne Johnson was exposed to glyphosate at levels most people will never encounter, and a jury decided he deserved compensation. That outcome is not evidence that the oatmeal in your pantry is dangerous. But it is a reminder that the dose, the context, and the person doing the exposing all matter enormously. Glyphosate is a chemical tool with benefits, trade-offs, and genuine open scientific questions. Learning to hold that complexity without collapsing into panic or dismissal is, honestly, one of the most useful and hardest things to do in navigating modern health science. Love, YLE Your Local Epidemiologist (YLE) is founded and operated by Dr. Katelyn Jetelina, MPH PhD—an epidemiologist, wife, and mom of two little girls. Hannah Totte, MPH, is an epidemiologist and YLE Community Manager. YLE reaches more than 425,000 people in over 132 countries with one goal: “Translate” the ever-evolving public health science so that people will be well-equipped to make evidence-based decisions. This newsletter is free to everyone, thanks to the generous support of fellow YLE community members. To support the effort, subscribe or upgrade below: Subscribe
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