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New weight loss pill beats oral Ozempic in major trial
A new once-daily weight-loss pill called orforglipron delivered better weight loss and blood sugar improvements than the leading oral semaglutide in a major clinical trial. The tablet could offer a more convenient alternative to injectable drugs like Ozempic and Wegovy because it doesn't require refrigeration or special timing with meals. It's also cheaper to manufacture, which could expand access globally.
OpenAI’s Chief Futurist Is Leaving the Company
Joshua Achiam spent nearly nine years at OpenAI researching AI safety and made a memorable appearance in the Musk v. Altman trial.
Lindsey Buckingham's Alleged Stalker to Undergo Mental Health Exam
Lindsey Buckingham's alleged stalker had her felony case suspended and will undergo a mental health exam to determine her suitability to stand trial.
The crumbling employer-based health insurance system
Today's D.C. Diagnosis newsletter covers maintaining diversity in drug trials and troubling trends in employer-based health insurance.
There's no treatment designed for the Ebola strain ravaging DRC. But now there's hope
The strain of the virus that's responsible for the current outbreak has no specific treatments or preventive measures. Three new clinical trials could provide possible breakthroughs.
Thousands of acres, billions in investment: What's next for RiverPlex MegaPark?
The RiverPlex MegaPark is still years away from reaching its full potential, but the foundation is being laid for what could become one of the Gulf Coast’s largest industrial hubs, according to Ascension Economic Development Corporation President and CEO Kate MacArthur. With roughly $10 billion in announced investment already committed and thousands of acres still […]
Four states seeking $1.4 trillion in penalties in child social media addiction trial, Meta says
Four states are seeking $1.4 trillion from Meta over claims Facebook and Instagram were designed to be addictive to children without any warnings on the alleged harms of the apps.
The science of solving crimes
Every criminal case comes with a story. For years, Florida Gulf Coast University’s (FGCU) Human Identity and Trauma Analysis team has helped law enforcement uncover these stories, bringing science to some of Florida’s most complex investigations. The Michael Haim Trial in 2019, the “Baby Moses” cold case in 2016, and the Tulsa Race Massacre Excavation
New Anthropic data center coming to Kentucky town
Terawulf announced that Anthropic signed a 20-year lease for a "purpose-built AI infrastructure campus" at a former industrial site in Kentucky.
Ebola deaths in Congo top 500 as health workers threaten to strike
Frontline workers have threatened to strike over unpaid benefits and poor working conditions.
Ebola deaths in Congo top 500 as health workers threaten to strike
Authorities report that at least 500 people have died from over 1,500 confirmed Ebola cases in Congo.
IFT: Proposed US federal grant rules threaten nutrition science funding & competitiveness
The US Office of Management and Budget (OMB) recently proposed rules to rewrite the Uniform Guidance — the rulebook for all federal grants. Institute of Food Technologists (IFT) chief science and technology officer tells Nutrition Insight that these rules are set to undermine the nation’s scientific research for food and nutrition and hinder global competitiveness.
Inside the $85 million private jet that made one of Africa’s richest billionaires the owner of the world’s fastest business jet
Months after entering service, Bombardier’s Global 8000 has arrived in Africa, with one of Nigeria’s most powerful industrialists becoming its first customer on the continent in a move that flexes both aviation ambition and billionaire financial muscle, especially for a buyer who already owns two other Bombardier jets
Impeachment trial for Philippine Vice President Sara Duterte begins
The frontrunner to succeed President Ferdinand Marcos Jr will be barred from public office if convicted.
Summer McIntosh breaks longstanding 200-meter butterfly world record at Canadian trials
Summer McIntosh broke the longest-standing individual world record in women's swimming on Sunday night in Montreal.
Residents in eastern Congo cling to hope as a new Ebola treatment trial begins
At the Ebola treatment center inside Bunia's Evangelical Medical Center, in eastern Congo's Ituri province, the launch of the research was marked by urgency rather than ceremony.
Residents in Congo cling to hope as Ebola treatment trial begins
Survival will be tracked for 28 days after starting treatment
Residents in Congo cling to hope as a new Ebola treatment trial begins
Residents at the epicenter of Congo’s Ebola outbreak are pinning their hopes on two experimental treatments.
Residents in Congo cling to hope as a new Ebola treatment trial begins
Residents at the epicenter of Congo’s Ebola outbreak are pinning their hopes on two experimental treatments.
Residents in eastern Congo cling to hope as a new Ebola treatment trial begins
Residents in Congo's Ebola outbreak zone are hopeful as researchers begin a study of two potential treatments.
Booz Allen Hamilton (BAH) to Buy Ultra I&C Mission Solutions Business for $720 Million
Booz Allen Hamilton Holding Corp. (NYSE:BAH) is one of the 12 best industrial stocks with more than 50% upside. The company’s acquisitive growth strategy is making it a compelling investment case. On June 22, Booz Allen Hamilton Holding Corp. (NYSE:BAH) signed a definitive agreement with an Advent portfolio company, Cobham Ultra Group, to purchase its […]
Vagus Nerve Stimulation Has a Profound Impact on Severe Depression, Major Trial Finds
“They had spent more than half of their lives sick."
Long Reads for the Long Weekend
(Welcome to the Entertainment Strategy Guy, a newsletter on the entertainment industry and business strategy. I write a weekly Streaming Ratings Report and a bi-weekly strategy column, along with occasional deep dives into other topics, like today’s article. Please subscribe.) Happy Fourth of July weekend! As has been a tradition of mine going back to the beginning of the EntStrategyGuy website, I’m sharing my favorite long reads of the last year, like I did in 2019, 2020, 2021, 2024, and 2025. Let’s dive right in! Subscribe “Different Prices for the Same Ride: How Uber and Lyft Use AI to Get More Money Out of You“ by Derek Kravitz in Consumer Reports I don’t think surveillance pricing, like the kind described in this brilliant Consumer Reports article, is long for the world—it’s toxically unpopular—but we’ll see if either party takes on this issue. If I ran a political party focused on affordability, I would focus on a few pro-consumer and pro-market policies: Banning non-compete agreements. Ending surveillance pricing Eliminating junk fees (read more here...) Ensuring “right to repair” for consumer (and military!) products Capping excessive app store fees Stopping digital/algorithmic price-fixing tools. Preventing automatic subscription price increases. And more. If you want to fight inflation, there are a lot of great ways to do it quickly. Speaking of higher prices... “Secret Documents Show Pepsi and Walmart Colluded to Raise Food Prices Across the Economy“ by Matt Stoller in BIG Again, I think a political party should focus on lowering prices for consumers. And deals like this—Walmart making a deal/forcing Pepsi to offer the lowest prices at its stores and nowhere else—hypothetically lower prices at Walmart...but raise them everywhere else. “15 DUIs, still driving: California’s failure to take repeat drunk drivers off the road“ by Robert Lewis and Lauren Hepler in CalMatters CalMatters does terrific reporting in California, something the Golden State desperately needs more of, and this article is a great example of that. “PugLips: The next insanely popular thing you’ve never heard of…” by Simon Carless in Game Discover Co I thought that this parody article (and yes, it’s a parody, but I was definitely unsure at first) was hilarious and totally nailed how much tech/business journalism feels these days. Actually, three of my favorite articles this year were on hype in the video game industry, including Georg Zoller’s “The Video Game Industries Very Dark Night”—which I linked to recently and wrote a follow-up here—and Owen Mahoney’s “Derek Zoolander, Videogame Exec”. In particular, I like Mahoney’s focus on user experience as a guide to what trends will actually grab hold of customers. “The Matrix Lies“ by Evan Shapiro in Media War & Peace Evan Shapiro’s first person account of his experience with AI was hilarious. I think LLMs capabilities have significantly grown from last summer, and yet...my editor/researcher just had an abysmal experience using an LLM to do a quite basic task (which our LLM normally does each week) and the LLM made a mistake on every single data entry...along with seven different mistakes affecting twelve of the twenty or so entries, including mistakes that are explicitly spelled out in the prompt. That’s a brutal failure rate. Again, if you use AI/LLM for data collection, you need to take a lot of extra steps to verify and check the data. “Ghosts in the Balcony: A Cross-Country Trip to 58 Theaters Fighting to Survive“ by Matthew Frank in The Ankler I thought Matthew Frank’s pitch to head across America to visit theaters sounded insane aggressive at the time—at least it felt that way to someone a decade older than him; man, to be in your twenties again, am I right?—but I knew the result would be great. And it was, a terrific feature by a great young writer. Also, I loved Matthew’s recent article on who’s getting the precious few entry level jobs in Hollywood. (Hint: nepotism.) “Disney erased FiveThirtyEight“ and “Did Las Vegas get too greedy?” by Nate Silver in Silver Bulletin I love media history and analysis, and there’s no one better to get the history of FiveThirtyEight than from Nate Silver, who wrote about his personal experience in one of my favorite pieces from this year. I also loved Nate’s breakdown of what’s causing Vegas’ woes, but I’ll offer one criticism, summarized as “Might I suggest antitrust?” Many centrists/center-right/libertarian thinkers (Nate is self-described as the latter) often don’t consider consolidation or antitrust as factors in policy issues like housing, America’s military readiness, or, in this case, Las Vegas. Even if libertarians want to debunk antitrust/consolidation concerns, I’d love to read that debunking. In this case, Vegas is incredibly consolidated (though it also has been for a long time) and I’d have loved to read Nate at least contending with this factor, since he addresses almost every other potential factor for Vegas’ decline. “Why Microsoft’s Carbon Removal Pullback Is Such a Big Deal“ by Robinson Meyer in Heatmap News I’m a big supporter of carbon removal efforts, but this nascent industry faces a lot of headwinds, including this big move most recently. I think it’s clear that solar panels and batteries should be able to get the world to its carbon footprint goals, but effective carbon renewal remains necessary to prevent the worst impacts of global warming. “AI is killing the cheap smartphone“ by David Oks LLMs and AI will impact the world in ways we’re not ready for, and already, third world countries are seeing the prices of cheap cellphones skyrocket due to the cost of chips skyrocketing. This article by David Oks is a terrific breakdown. “100 Days of Madness: Netflix, Paramount, Warner and the Future of Hollywood“ by Wade Major at Hollywood Heretic Wade Major dove deep into Hollywood/streaming’s financials in this must read piece. Not that I agree with everything in this article (read my take on Warner Bros./Paramount here) but the analysis is top notch. I think many people discount how quality thinking, regardless of the argument/conclusion, will make you a better thinker. “Erased by the UFC: Frank Shamrock, The MMA GOAT of the 20th Century“ by Nate Wilcox in The MMA Draw Newsletter Growing up playing the UFC fighting game on the Dreamcast, Frank Shamrock was my favorite MMA fighter, and this history/tribute to him was great. Other Fun Reads “The Hardest Part Of History To Tell Is How It Felt“ by Craig Fehrman at Defector “Unmasking the Sea Star Killer“ by Craig Welch at bioGraphic “What Could Save the Industry? Fin-Syn“ by Richard Rushfield in The Ankler Alex Rollins Berg in Underexposed on movie bumpers, pillow shots, Disney trash cinema, cult films, and Casablanca. David H. Montgomery in YouGov’s The Surveyor on punctuation marks, condiments, dinosaurs, and comic strips and kids media. “How Medium finally pivoted its way to profitability“ and “Why the best journalists on YouTube are all former Vox employees“ by Simon Owens in Simon Owens’s Media Newsletter “It’s Not Just You, Netflix Shows Have Gotten Slightly Shorter: Here’s What the Data Says“ by Kasey Moore at What’s on Netflix “Numlock Awards: How Diane Warren became the biggest loser in Oscar history“ by Nathaniel Rakich and “Numlock Awards: The Oscar Bait era is over. The Oscar Chum era is here.” by Walt Hickey & Michael Domanico at Numlock Awards
Businesses on the move in Marin and Sonoma counties: July 2 report
Check out which companies are leasing and buying office, retail, industrial and residential development properties in Sonoma and Marin counties via the following deals.
Step Into the Modern Era in EA SPORTS College Football 27 with EA Play
It's time to take the gridiron in EA SPORTS College Football 27. Get game-day ready with an EA Play 10-hour early access trial.
Ex-Mayor LaToya Cantrell’s federal trial is delayed again. See when it’s set to happen.
The delay until May 2027 is the latest wrinkle in the legal case against New Orleans’ former mayor.
Trial for Bundibugyo Ebola treatment starts in DRC, WHO says
A treatment trial for the Bundibugyo Ebola outbreak in the Democratic Republic of Congo enrolled its first patient on Thursday, marking a milestone in efforts to combat the epidemic, WHO chief Dr. Tedros Adhanom Ghebreyesus told reporters.
Patient enrolment begins in a scientific trial to identify the first effective treatments for Bundibugyo virus disease
In a major international effort to evaluate potential treatments for Ebola disease due to Bundibugyo virus (BVD), the PARTNERS clinical trial has opened enrolment today for patients in the Democratic Republic of the Congo.
Scientists devise new method for tracing environmental PFAS contamination better
Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are a class of synthetic chemicals widely used in industrial processes and consumer products because of their resistance to heat, water and oil. However, ...
How Bridge Entertainment Labs' Steven Olikara Is Building Community Across America's Deepest Divides
Steven Olikara identifies a "division industrial complex" where media and politics profit from societal polarization, fostering hatred based on false narratives. To counter this, Olikara, drawing from...
How Bridge Entertainment Labs' Steven Olikara Is Building Community Across America's Deepest Divides
Steven Olikara identifies a "division industrial complex" where media and politics profit from societal polarization, fostering hatred based on false narratives. To counter this, Olikara, drawing from his experiences in music and politics, founded Bridge Entertainment Labs.
Iowa small businesses encouraged to compete for federal defense contracts
Iowa small business owners are being encouraged to compete for billions of dollars in government contracts as the federal government looks to expand its defense industrial base.
Iowa small businesses encouraged to compete for federal defense contracts
Iowa small business owners are being encouraged to compete for billions of dollars in government contracts as the federal government looks to expand its defense industrial base.
U.S. Army Contracting Command personnel recognized for streamlining small business procurement
At the FY25 Department of War and Department of the Army Small Business Awards, Army Contracting Command (ACC) was honored for strategic acquisition reforms that diversified and strengthened the defense industrial base.
Nation’s largest industrial landlord bets $100M on Chicago warehouse demand
The project is a show of confidence by one of the biggest industrial property companies that the Chicago-area warehouse market has pent-up demand.
Scientists say creatine may help fight depression
Creatine is best known as a muscle-building supplement, but scientists are now investigating whether it could also help treat depression by boosting the brain's energy supply. A new review examined five randomized clinical trials involving 238 participants and found mixed results. Two studies, both involving women with major depressive disorder, reported that adding creatine to standard treatment improved symptoms, while three others found no meaningful benefit.
Why scientists fear we're missing evidence of extraterrestrial life
Scientists are raising concerns that we may be overlooking evidence of extraterrestrial life even when it is present. Hidden biosignatures, limitations in detection technology, and assumptions about what life should look like can all create dangerous false negatives. The researchers say future missions should focus not only on finding life, but also on understanding how signs of life could be missed.
Mangione faces hearing ahead of trial over US health insurance CEO's killing
Luigi Mangione, the man accused of fatally shooting a health insurance executive on a Manhattan sidewalk in 2024, is due for a hearing in federal court on Monday ahead of his federal trial on stalking charges after murder and weapons charges were thrown out.
Ingredion plans global Benicaros prebiotic expansion across gut and immune health applications
Ingredion highlights that its recent acquisition of the Benicaros prebiotic is a strong strategic addition to its Healthful Solutions portfolio, supporting the company’s formulation versatility alongside expansion of health-forward and clean label ingredients. The company purchased the patented prebiotic fiber, made from upcycled carrot pomace, from NutriLeads earlier this month. With the deal, Ingredion obtained full ownership of all intellectual property, trademarks, human clinical trials, and know-how related to manufacturing Benicaros.
Benchmark Scores Don’t Break. Clinical Reality Does. The Health AI Readiness Illusion.
Nature Medicine's frontier AI evaluation exposes a dangerous gap: models acing medical benchmarks collapse under adversarial pressure, and the FDA has no…
Efzimfotase alfa demonstrated improvements in bone health in treatment-naïve pediatric patients with hypophosphatasia achieving median difference of 1.67 vs placebo in RGI-C Score at week 25 in MULBERRY Phase III trial
Positive results from the MULBERRY Phase III trial showed that efzimfotase alfa (ALXN1850), an investigational enzyme replacement therapy, demonstrated a statistically significant and clinically meaningful improvement in bone health in children (2 to
How To Watch BET Awards 2026
Watch BET Awards 2026 live with TV channel, start time and streaming info. Stream on Fubo — no cable required, free trial available.
He’s no longer allergic to the sun, thanks to a clinical trial. Meet Louisiana's ‘vampire guy.’
“I was missing a lot,” Pierre Mouledoux said. “But I'm not missing out anymore.”
Government overreach won’t fix youth gender medicine
The real cure for bad science is better clinical trials, not lawsuits.
Government overreach won’t fix youth gender medicine
The real cure for bad science is better clinical trials, not lawsuits.
Moderna highlights expanding mRNA platform at Science Day
Moderna's Horizon programme contains a variety of mRNA assets in varying stages of development, including a preclinical in vivo candidate.
Morocco jails 29, including politicians and sports figures, in drug trial
Casablanca court delivers landmark verdict in 'Escobar of the Sahara' case: up to 12 years for top figures.
Harvey Weinstein rape charge dismissed after mistrial
Prosecutors are dismissing Harvey Weinstein's rape charge involving Jessica Mann.
The Painting That Is Still on Trial in South Korea: How the unending Korean War became a permanent excuse to criminalise expression
By Boram Jang, East Asia Researcher at Amnesty International In a Seoul courtroom in March this year, a prosecutor read out charges against Jeon Seung-il, a former art student, from an indictment first written in 1989. The language had not changed, nor had the charges. Thirty-seven years later, only the young defendant had grown old. In 1989, he was 23 years old in a South Korea still shaped by decades […]
What an abandoned heart failure trial says about 'breakthrough' devices that don’t reach patients
An abandoned heart-failure trial offers a rare window into devices that the FDA deems "breakthrough" but never reach patients.
3 people in Oklahoma indicted in nationwide health care fraud probe
Three people in Oklahoma were indicted in a nationwide health care fraud probe involving nearly 500 people, including dozens of doctors.
Race, politics fueled airport takeover effort, Jackson Mayor Horhn testifies
Jackson Mayor John Horhn was the second witness called in Day 2 of Jackson's airport takeover trial.
First patient receives neural stem cell therapy in groundbreaking UCI Health Huntington's disease clinical trial
World’s first neural stem cell phase 1b/2a clinical trial for condition leverages innovative technology
Hunt the Death Cult in Season of Death Awakening
Seek out new threats from the Death Cults, dominate the Tower and Leaderboards, and enjoy a free Warlock Trial in Season of Death Awakening.
Want to age better? Researchers say 4-minute routine may help prevent dangerous falls
A Penn State clinical trial finds just four minutes of daily strength exercise can improve mobility, balance, and leg strength in older adults.
Health officials launch clinical trial reforms to counter China threat
The Food and Drug Administration (FDA) on Monday launched a new initiative to speed up early-stage clinical trials as part of an effort to reduce development timelines and reverse a growing trend o…
Opinion: Chicago is where automation moves from idea to industry
With Chicago hosting North America’s largest robotics and automation event this week, it showcases being a practical hub for the next era of industrial automation.
Federal health agencies unveil plan to speed up phase 1 clinical trials by 6 to 12 months
As the biotech world flocks to San Diego today for the BIO International Convention, the Department of Health and Human Services has provided plenty of conversation fodder with the announcement of | As the biotech world flocks to San Diego today for the BIO International Convention, the Department of Health and Human Services has provided plenty of conversation fodder with the announcement of a series of efforts to regain ground on China’s surging early-stage clinical development capabilities.
FDA to launch pilot program to speed up early-stage clinical trials
Federal health officials aim to speed up drug development and better compete with China.
Chris Brown $90 million lawsuit ends in mistrial
The $90 million lawsuit against Chris Brown over an alleged dog attack has been declared a mistrial.
A common vitamin could help fight one of the deadliest brain cancers
A clinical trial is exploring whether high doses of vitamin B3 could give patients with glioblastoma a better chance against the aggressive brain cancer. Scientists found that niacin may help revive immune cells that tumors shut down, allowing them to attack cancer more effectively. Early results have been promising, with patients showing significantly better progression-free survival than expected.
UVA Health clinical trial works to target MAC lung disease
Research at UVA is working to find new treatment opportunities for a lung disease growing in prominence around the world.
How to Watch The Way Home Season 4 Finale
Watch The Way Home live with TV channel, start time and streaming info. Stream Season 4 Finale on Fubo — no cable required, free trial available.
How to Watch House of the Dragon Season 3 Premiere
Watch House of the Dragon live with TV channel, start time and streaming info. Stream Season 3 Premiere on Fubo — no cable required, free trial available.
Luigi Mangione plans to withdraw mental health crisis claims
Luigi Mangione's attorneys have withdrawn their plan to allege at trial that he was undergoing a mental health crisis, court filings revealed on Friday. Mangione pleaded not guilty in 2024 to the murd...
Commentary: ‘Disclosure Day’ underscores a Hollywood marketing dilemma
From "Close Encounters of the Third Kind" to "E.T. the Extra-Terrestrial" and "War of the Worlds," a UFO-themed blockbuster from Steven Spielberg has long been a can’t-miss event, and last
Entrepreneurs and small business owners: The importance of furthering your education
Commentary: When people think about entrepreneurship, they often picture someone diving in headfirst, learning through trial and error, and figuring things out along the way.
A brain-computer interface has, for the first time, restored fluent everyday speech to a person who had lost it — a man with ALS who had not spoken aloud in years until a small implant from the BrainGate clinical trial began translating his attempts to speak directly into computer-synthesised words, in a result researchers reported in June 2026
Casey Harrell can now talk for twelve hours at a stretch. Two years ago, he could not talk at all. The ALS he was diagnosed with several years earlier had progressively destroyed the motor neurons controlling the muscles of his face and throat, leaving him with the symptoms doctors call dysarthria and, eventually, anarthria — […]
Watching water nanodrops spread themselves thin
Researchers at the Institute of Industrial Science, The University of Tokyo, have determined the molecular origin of line tension for a water nanodroplet on a surface. This tension is the force along the droplet edge where liquid, solid, and gas phases meet. Computational studies showed that at complete wetting, collapse of tetrahedral order in liquid water causes the line tension to change sign. An ice bilayer did not wet a hydrophilic surface, showing that local order can outweigh surface chemistry.
Mangione, accused CEO killer, withdraws mental health defense plans for now
Luigi Mangione, the man accused of gunning down a health insurance executive on a Manhattan sidewalk, is for now withdrawing plans to argue at trial that he was undergoing an extreme mental health crisis at the time of the alleged killing, according to a Friday court filing.
Mangione, Accused CEO Killer, Withdraws Mental Health Defense Plans for Now
By Jack Queen NEW YORK, June 18 (Reuters) - Luigi Mangione, the man accused of gunning down a health insurance executive on a Manhattan sidewalk, is for now withdrawing plans to argue at trial that he was undergoing an extreme mental health crisis at the time of the alleged killing, according ...
Arsenal Capital Partners Adds Max Schechter as Head of Industrial Growth Business Development
/PRNewswire/ -- Arsenal Capital Partners ("Arsenal"), a middle-market private equity firm specializing in building industrial growth and healthcare companies,...
Tech Founder’s Downfall in Indonesia Shows Rising Business Risks
The trial of one of Southeast Asia’s most successful entrepreneurs is adding to concern about governance under President Prabowo Subianto.
WHO Step-by-Step programme recognized as a promising innovation for mental health in humanitarian settings
WHO, in collaboration with the Pan American Health Organization (PAHO) and Lebanon’s National Mental Health Programme, showcased Step-by-Step at the World Bank Group’s biennial Fragility Forum in Washington, DC. The forum convened more than 1500 representatives from governments, international organizations and civil society to advance the development agenda in the world’s most fragile and crisis-affected communities. WHO was invited to demonstrate Step-by-Step – a digital self-help intervention for depression, alongside innovations presented by Stanford University and Google. The World Bank Group selected Step-by-Step from among more than 50 innovations that they reviewed in the lead up to the Forum.About Step-by-StepStep-by-Step is a free digital tool developed by WHO in collaboration with Lebanon’s National Mental Health Programme and other partners, that helps people manage depression and anxiety on their own, with light guidance from a trained supporter. It uses a picture-based story to walk users through evidence-based techniques for managing common mental health conditions. Users complete five modules, with weekly contacts – of around 15 minutes each – from a trained non-specialist helper, such as a community health worker.Evidence-basedClinical trials in Lebanon involving nearly 1250 participants – including 680 Lebanese participants and 569 Syrian participants – showed that Step-by-Step significantly reduced depression, anxiety and stress, and improved daily functioning. By the end of the programme, a reduction in depressive symptoms of more than 50% was reported by almost half (46%) of Lebanese participants and more than one third (37%) of Syrian participants compared to approximately 14% of those who did not use the programme. Cost-effectiveness analyses further suggest that Step-by-Step may offer a cost-saving response to depression in humanitarian emergencies in low- and middle-income countries.Used globallyStep-by-Step is already in use nationwide in Lebanon and Thailand, as part of each country’s mental health system. In India, the NGO – Kaya Guides – has adapted Step-by-Step for delivery through a widely used messaging app. Together, these programmes have provided thousands of people with evidence-based support for depression. The content is freely available from the WHO website for any organization or country to adapt for their own context.A new implementation guideThe Fragility Forum coincided with the recent launch of WHO’s new practical guide: Psychological self-help interventions: delivering self-help for individuals, featuring Step-by-Step and Doing What Matters in Times of Stress (WHO, 2026). The guide is designed to help governments, health workers, organizations and planners bring evidence-based mental health support to more people, particularly in low-resource and crisis-affected settings.
A daily probiotic may help relieve depression and anxiety
A small clinical trial suggests that probiotics may offer a surprising mental health boost for older adults with depression. Seniors who took a daily probiotic alongside their regular antidepressant treatment experienced slightly greater improvements in depression and anxiety symptoms than those who received a placebo.
Small Business Administration chief talks the state of small businesses in the U.S.
The Reindustrialize Summit convened leaders from manufacturing, technology, defense and finance in Detroit to discuss how to restore America’s industrial strength. Small Business Administration Administrator Kelly Loeffler sat down with CNBC’s Leslie Picker for a conversation on boosting America’s manufacturing base, small business sentiment, and AI’s impact to Main Street.
How a biotech turned a trial failure into an AI model
In this edition of STAT Health Tech: How a biotech startup turned a failed clinical trial into an AI model, and more.
June 16, 2026: LungSMART Team Uses Bilingual Formative Evaluation to Hone Study's Digital Health Content
The LungSMART research team conducted a bilingual messaging study and usability assessment to evaluate and adapt the study’s digital health content for patients in community health centers in Utah. The […]
Hong Kong Science Park, SenseTime partner to build home-grown AI data centre
Project to be built in three stages, targeting 40,000 petaflops of computing power by 2030 to drive sector’s industrialisation.
James Manyika
The Google senior vice president talks about the need to reset the relationship between the government and academic and industrial science
L.A. Sites Included in Major Deal
Editor's note: A version of this story was originally published in the Orange County Business Journal. In one of the largest light industrial deals of the
Rape trial verdict due in the case of Norwegian crown princess' eldest son
A Norwegian court is set to deliver its verdict and sentence in the trial of Crown Princess Mette-Marit's eldest son Marius Borg Høiby | KYW Newsradio
“Disclosure Day ”lands out-of-this-world opening weekend with $93 million at global box office
While Steven Spielberg's extraterrestrial drama invades the world, 24-year-old Curry Barker's low-budget horror "Obsession" achieves a rare domestic feat.
UVA Health program looks to reverse children drinking too many sugary drinks
The trial has six education components to bring mindfulness and reduction to sugary drink consumption
Sarasota business park land sold to investor planning apartments
In the week's top commercial real estate news, a 100,000-square-foot industrial site leased in Tampa, 1,000 homes will be built in Lakewood Ranch, and a grocer-anchored center sells in Seffner.
Essex GPs trial for adults with learning disabilities
Not enough eligible people are having life-saving annual health checks, say experts.
Honeywell Sees Strong M&A Opportunities in Industrial Automation Business
Honeywell International Inc. (NASDAQ:HON) is included among the 10 Best S&P 500 Dividend Stocks to Buy Right Now. On June 11, Reuters reported that Honeywell International Inc. (NASDAQ:HON) is targeting acquisitions valued between $2 billion and $4 billion and sees significant opportunities for deals within its industrial automation business. “There is a ton of opportunity […]
New York's victorious Knicks leave World Cup in the cold
The World Cup carnival arrived in New York on Saturday, but it was drowned out by the city's elation after the hometown Knicks broke a 53-year curse to win the NBA Finals.- No 'big buzz' - In an industrial section of Brooklyn, the manager of an indoor five-a-side arena said ahead of the Knicks win that "obviously the Knicks, as they should, are over-shining" the World Cup.
Spielberg’s new alien movie asks: Who gets to decide the truth?
In 1977, Steven Spielberg’s "Close Encounters of the Third Kind" imagined contact with aliens as an event inspiring awe. Five years later, "E.T. the Extra-Terrestrial" envisioned another arrival as a
Trump and Macron will meet over dinner at Versailles palace after G7 summit in France
President Donald Trump and French President Emmanuel Macron will meet over dinner at the Palace of Versailles after the upcoming G7 summit of leading industrialized nations in France
Scientists Race to Test Treatments as Ebola Outbreak Widens
Trials are beginning on several drugs that have shown promise in preliminary studies against the virus that is causing the current outbreak.
Wellston Industrial Park to Transition to Manufacturing, Logistics Business Park
City of Wellston, County LCRA working with THO Investments on project Working together, the Land Clearance for Redevelopment Authority of the County of St. Louis (LCRA), managed by St. Louis…
Penn study finds GLP-1 use associated with lower breast cancer risk; researchers to launch clinical trial
Women in the study who were obese and taking GLP-1 weight loss medications were 30% less likely to develop breast cancer than other women.
New map estimates health impacts from oil refineries across the Mountain West
People living near oil refineries can often see or smell signs of industrial pollution. Now, a new interactive map aims to help them better understand the potential health impacts associated with those facilities.
Cell Therapy Clinical Trials: Breaking Down the Science
Breakthrough T1D is here to answer all of your questions about islet cell therapies, from the research lab to real-world treatments.
New OMB rule could break science in the United States
The drug that saved your mother. The treatment your doctor recommended. The clinical trial that bought someone you love more time. None of it was inevitable. It required a system built to operate outside politics and sustained over decades, because science doesn’t operate on the timeline of a politician. That system is now under direct threat. The Office of Management and Budget (OMB) has proposed a new rule to regulate all federal grants, not just science, but housing, education, defense, NASA and everything in between, that would fundamentally change how research is conducted in the United States. There have been a lot of fires in the past 16 months, and if everything is an emergency, nothing is an emergency. But this is a very big deal. These rules would strip away the independence that has kept science from becoming a political tool. The good news is there’s still something we can all do. How the grant system was designed to work When I was a new faculty member, I was full of millions of ideas, so I sat down and wrote an NIH proposal. I worked on it for months and thought it was so good. Then I sent it to my mentor. It came back covered in comments. Places where my reasoning wasn’t as airtight as I’d thought, methods that could be stronger, gaps in my thinking that I had been too close to the work to see. It stung, as honest feedback always does, but peer review almost always makes the work better. In fact, it’s the backbone of how American science has functioned for generations. At NIH, submitted proposals go to a panel of scientists who have experience in the field. These are the people who can read research methods and spot their weaknesses, who understand when an experiment is designed well and when it isn’t. Applications are scored rigorously, and often only the top 3-20% of proposals receive funding. The people making funding decisions are required to justify them based on these reviews. To be clear: this is not a perfect system, and good science still goes unfunded more often than any of us would like due to limited resources. There is also criticism that peer review may undervalue bold ideas that are risky but could have high payoffs. But the peer review system is nonetheless a meaningful part of the grant selection process. While thoughtful and careful changes could improve the system, the changes being proposed by OMB will not make things better. The rule that could change everything Through this OMB proposal, the system that helps decide what gets funded is being dismantled. There are many troubling elements buried in this proposal, but three provisions stand out in particular. Each would be damaging alone. Together, they would change what kind of science gets done in America, and who it serves. 1. Political appointees would decide which science gets funded, and peer review would be explicitly sidelined or ignored. The guidelines your doctor follows, the standards that determine what’s in your air and water, the drugs that get approved for your family: all of it starts with a funding decision. Right now, that decision is made by scientists who can evaluate whether the work is actually sound and whether it could move the needle forward. Under this proposal, funding decisions could be made by political appointees. The careful, expertise-driven review process that shapes grant funding would be effectively sidelined. That means that a poorly designed study could get funded simply because someone in a political office liked the sound of it, while rigorous, important work doesn’t get funded because it no longer aligns with the administration’s priorities. In other words, critical work that benefits all of us could now be missed just because it has become politically inconvenient. 2. Grants could be canceled at any point, without warning, in the middle of ongoing work. Say your tax dollars have been paying for a cancer study for two years. The grant was awarded for five years, so the team is mid-experiment. There are three additional years’ worth of answers that could change how the disease is treated for hundreds of thousands of people. With this new rule, the federal government could cancel the remaining funding tomorrow, walk away from the commitment it made with your money, and have no legal obligation to finish what it started. This is a huge waste of money. There are rarely other sources of funding for this work, which means the team, the graduate students, postdocs, and research staff who have dedicated years of their careers to this project could lose their jobs. Patients who have contributed their time to studies may not see it turn into useful learnings for others. Every hour of work already completed could result in nothing useful. Science can take decades to get to tangible outcomes. It needs a stable funding system to flourish. 3. Researchers would have a harder time communicating their findings without pre-approval from the federal government. There is a saying from Sir Mark Walport: “Science isn’t finished until it’s communicated.” Science is no use to anyone if it is kept locked away in the labs that produced the data. The proposed rule could make communicating research findings harder in a number of ways: Make it harder for scientists to widely share their findings in scientific journals. Publication costs, including journal fees that allow for broad public access, could not be paid for by federal funds which is often how scientists pay these costs. Restrict researchers from engaging publicly about how their findings should inform policy or public health guidelines. This would restrict scientists from doing the work that transforms years of lab work into decisions that actually affect people’s lives. Make it harder for scientists to attend conferences. Conferences would now need to be approved by the federal agency at the time of grant award. This disadvantages conferences or publications that are not politically aligned. Conferences are a key way in which scientists learn about work happening in their field so they can collaborate and build on each other’s findings. What good is science with a muzzle? The long-term impact These changes could (and hopefully would) be reversed under the next administration. But by then, damage has been done. Once projects are halted or denied funding by political appointees, people leave their science careers for other paths or even leave the country to do their amazing science elsewhere. You cannot pause a scientific study the way you pause a subscription you decided isn’t useful anymore. You cannot freeze a research team that depends on salaries to feed their families, causing a scramble for replacement funding that, in most cases, simply does not exist. When the money stops, everything stops, and all the work in progress and its potential are lost. Despite all of the language about reducing waste, fraud, and abuse, this new proposed rule increases the administrative burden tremendously. Every researcher watching this unfold will make a rational decision: don’t start anything that will take a decade to finish. This includes not building a team around funding that could vanish, or asking the big questions that need patience and stability to answer. The most consequential science, the kind that produces the treatments and the breakthroughs that reach your doctor’s office twenty years from now, is exactly the science that would be abandoned first. This is still a proposal, so we can all do something Some worry this rule is already a done deal. But by law, OMB is required to open a public comment period. Those comments matter because they inform members of Congress, they can be used in litigation, and they create a public record. So here’s what you can do: Submit a public comment. The public comment period on this proposed change is open until July 13. Anyone can submit a comment, and OMB is required to respond to substantial ones. Each comment must be different to count as distinct; identical comments will be counted only once. Comment as an individual, not on behalf of your organization. Here’s a full resource to help you, with useful examples, but in general: Share a story about how science or federal funding has benefitted you or is involved in your work. Are you or someone you loved a cancer survivor? Do you know someone with Alzheimer’s? Have you received NIH/NSF or other federal funding? All of these can be stories you use to highlight why you care. Explain why you’re worried about these proposed changes. You can use the wording found here or in other resources to help you. Ask them to withdraw this proposed rule. Contact your elected representatives. Congress allocates money to federal agencies to spend, and it has oversight of how that process works. You can let your representatives know this proposed change concerns you and ask them to intervene. There are levers they can push that can help at this moment. Let others know why federal funding matters. This isn’t just about science, but ALL federal grants, including for education systems, defense projects, and more. The process, including the importance of federal funding, is invisible to many. We can all make it more visible by sharing how science benefits us and why we value it. You can also share this article, or any of the resources linked here, to help spread awareness! Bottom line We are quickly losing ground in scientific research in the U.S. More changes, like the proposed rule by OMB, would decimate our ability to conduct research here, leaving us all worse off: fewer treatments for pancreatic cancer, less research on pollution impacts, fewer answers for patients with rare disease, and more unaddressed health needs. The impact will be very real for all of us, regardless of where we stand politically. Using our voices for science is more important than ever. Love, LM Big thanks to Dr. Megan Ranney for reading this over and providing brilliant insights, as always. Dr. Liz Marnik, PhD, is Executive Director of The Evidence Collective at YLE and a science communicator and immunologist working at the intersection of public trust, science, and public health. You can find her on Substack, LinkedIn, Instagram and Threads. Your Local Epidemiologist (YLE) comprises a team of experts, ranging from physicians to immunologists to epidemiologists to nutritionists, working together with one goal: to “Translate” ever-evolving public health science so that people are well-equipped to make evidence-based decisions. The YLE suite of newsletters reaches over 475,000 people across more than 132 countries. This newsletter is free to everyone, thanks to the generous support of fellow YLE community members. To support the effort, subscribe or upgrade below: Subscribe
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