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Berrien County Health Department warns parents, teens about kratom risks

The Berrien County Health Department is launching a campaign warning parents and teens about the risks of kratom. According to the health department, kratom contains a chemical called 7-hydroxymitragynine, or 7-OH, that acts like an opioid and can cause severe withdrawal symptoms.

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Oct 20 • 12:50 PM EDT • Health • wndu.com
I Bought This Low-Mileage Jeep Grand Cherokee For Only $1,700 After Realizing My 'Holy Grail' Project Is Doomed

“David, can you please fix the garage?” my wife Elise asked me on Sunday. “You barely have any time to do house stuff, and today you’re free.” She’s right about the first part — The Autopian really does take up all of my time, and the garage does need to be fixed — but she […]

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Oct 20 • 12:45 PM EDT • Technology • theautopian.com
Big 12 commissioner talks future of CFP, Protect College Sports Act

What's the future of football conference title games and basketball tournaments? Brett Yormark addressed the effects of postseason expansion at Big 12 media days.

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Oct 20 • 12:23 PM EDT • Sports • sports.yahoo.com
Powerhouse UCSB team awarded big grant to investigate mathematical foundations of AI

Researchers Nina Miolane, Haewon Jeong, Sanjuka Krishnagopal and Yao Qin win $1 million from NSF for their collaborative investigation

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Oct 20 • 12:22 PM EDT • Science • news.ucsb.edu
Ice Cream Shop Owner Brought Her Kids to Work. Then the Health Department Arrived

“I’m sick of people acting like kids don’t belong,” the Michigan business owner tells TODAY.com.

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Oct 20 • 12:21 PM EDT • Health • today.com
iOS 27.2 adds new features in six iPhone apps, here’s what’s coming

iOS 27.2 launches next week with new features for iPhone users, including improvements across six Apple apps. Here’s what’s coming.

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Oct 20 • 12:18 PM EDT • Technology • 9to5mac.com
Villion: Code launches January 26, 2027 in the west

Compile Heart-developed action RPG Villion: Code will launchfor PlayStation 5, Switch 2, PlayStation 4, Switch, and PC via Steam on January 26, 2027 in the west, publisher Idea Factory Internationa…

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Oct 20 • 12:01 PM EDT • Technology • gematsu.com
Chesapeake Bay Health Reaches 20-Year High, but Work Remains

The Chesapeake Bay earns its highest health grade in 20 years, restoration efforts progress but ongoing challenges remain. The Chesapeake Bay earned its

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Oct 20 • 12:00 PM EDT • Health • conduitstreet.mdcounties.org
Police investigating homicide after woman found dead in Dauphin County business

DAUPHIN COUNTY, Pa. (WHTM)– Police launched a homicide investigation after a woman was found dead inside a Dauphin County business on Tuesday morning, according to the Swatara Township Police…

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Oct 20 • 12:00 PM EDT • Business • abc27.com
Scientists Built a Membrane That Breaks Down ‘Forever Chemicals’ Instead of Just Trapping Them

The membrane uses hydrogen and palladium to dismantle troublesome PFAS.

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Oct 20 • 11:58 AM EDT • Science • zmescience.com
Carrot Top returns to Vegas stage with dark jokes 1 month after suicide attempt

Carrot Top was met with love, cheers, and a standing ovation while returning to his Las Vegas residency one month after his sudden hospitalization.

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Oct 20 • 11:56 AM EDT • Entertainment • ew.com
Gimmick or giveback? Even some Trump supporters don't expect to get $5,000 checks after midterms

The offering of government checks has become a go-to tactic for President Donald Trump when he faces a political jam.

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Oct 20 • 11:27 AM EDT • Politics • pbs.org
Griffin Gaming Partners launches new joint production company

A prominent game industry fund and Hollywood talent agency are teaming up to adapt games for TV and film.

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Oct 20 • 11:10 AM EDT • Entertainment • gamedeveloper.com
MSU celebrates 25 Years of Imaging Sciences excellence

Morehead State University marks 25 years of undergraduate imaging sciences education, celebrating student success, faculty support and healthcare impact.

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Oct 20 • 11:10 AM EDT • Science • moreheadstate.edu
Negro Spirituals Royalty Initiative Is Launched

The Negro Spirituals Royalty Initiative (NSRI) is a new program, created by the Social Justice Matters team of South Congregational Church in Centerville and managed collaboratively with the Hyannis-based Arts

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Oct 20 • 11:00 AM EDT • Entertainment • capenews.net
XGIMI Launches AURA 3 Series, Bringing Cinema-Scale Entertainment to the Living Room

/PRNewswire/ -- XGIMI, a global leader in premium smart projection and home entertainment, today announces the official launch of its AURA 3 Series, a new...

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Oct 20 • 11:00 AM EDT • Entertainment • prnewswire.com
AREA15 developer pitches NBA arena as part of massive Las Vegas entertainment district

The developers behind AREA15 want to bring a future NBA franchise to their Las Vegas property, proposing an arena surrounded by a year-round sports and entertainment district.

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Oct 20 • 11:00 AM EDT • Entertainment • sports.yahoo.com
Visier Launches Vee Diagnostics Capabilities at HRTech 2026, Bringing Data Science Rigor to Everyday Talent Decisions

/PRNewswire/ -- Visier announced the early access launch of diagnostics capabilities within the Visier Workforce Insights Agent, Vee. Most organizations can...

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Oct 20 • 11:00 AM EDT • Science • prnewswire.com
AI scammers target sports fans with celebrity deepfakes

Our investigators reveal how scammers use AI to create convincing fakes of celebrities and athletes, targeting new schemes at fans

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Oct 20 • 10:51 AM EDT • Sports • wowt.com
AI scammers target sports fans with celebrity deepfakes

Our investigators reveal how scammers use AI to create convincing fakes of celebrities and athletes, targeting new schemes at fans

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Oct 20 • 10:51 AM EDT • Sports • kcbd.com
AI scammers target sports fans with celebrity deepfakes

Our investigators reveal how scammers use AI to create convincing fakes of celebrities and athletes, targeting new schemes at fans

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Oct 20 • 10:51 AM EDT • Sports • 1011now.com
New Tampa Bay business networking group launches

The organization helps connect company founders, executives, advisors and strategic partners.

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Oct 20 • 10:49 AM EDT • Business • stpetecatalyst.com
You Should Probably Check Your Google Home Speaker’s Data Usage

Google Home Speakers have been absolutely ripping through data—mine included.

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Oct 20 • 10:45 AM EDT • Technology • gizmodo.com
Interns In Florida Released A 16-Foot, 148-Pound Python Back Into The Everglades On Purpose. She Now Carries A Radio Tag For Drones To Follow - Futura-Sciences

In a state where around 100 contractors remove pythons all year round, letting one go looks like a mistake. It is how researchers find the others.

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Oct 20 • 10:45 AM EDT • Science • futura-sciences.com
Orlando Magic season preview: Opening schedule, win projection and what to know for 2026-27
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Oct 20 • 10:36 AM EDT • Sports • sports.yahoo.com
Indiana Pacers season preview: Opening schedule, win projection and what to know for 2026-27
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Oct 20 • 10:33 AM EDT • Sports • sports.yahoo.com
Cleveland Cavaliers season preview: Opening schedule, win projection and what to know for 2026-27
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Oct 20 • 10:33 AM EDT • Sports • sports.yahoo.com
Brooklyn Nets season preview: Opening schedule, win projection and what to know for 2026-27
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Oct 20 • 10:32 AM EDT • Sports • sports.yahoo.com
Toronto Raptors season preview: Opening schedule, win projection and what to know for 2026-27
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Oct 20 • 10:32 AM EDT • Sports • sports.yahoo.com
Phoenix Suns season preview: Opening schedule, win projection and what to know for 2026-27
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Oct 20 • 10:31 AM EDT • Sports • sports.yahoo.com
Golden State Warriors preview: Opening schedule, win projection and what to know for 2026-27
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Oct 20 • 10:31 AM EDT • Sports • sports.yahoo.com
Oklahoma City Thunder season preview: Opening schedule, win projection and what to know for 2026-27
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Oct 20 • 10:30 AM EDT • Sports • sports.yahoo.com
Minnesota Timberwolves season preview: Opening schedule, win projection and what to know for 2026-27
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Oct 20 • 10:30 AM EDT • Sports • sports.yahoo.com
Portland Trail Blazers season preview: Opening schedule, win projection and what to know for 2026-27
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Oct 20 • 10:30 AM EDT • Sports • sports.yahoo.com
Utah Jazz season preview: Opening schedule, win projection and what to know for 2026-27
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Oct 20 • 10:30 AM EDT • Sports • sports.yahoo.com
Now open in South Asheville, Novant Health launches new mammography mobile unit

Novant Health has launched a mobile mammography unit, bringing breast cancer screenings directly to Western North Carolina communities.

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Oct 20 • 10:29 AM EDT • Health • wlos.com
Berkshire Hathaway Specialty launches in Poland

U.S.-based Berkshire Hathaway Specialty Insurance Company has entered the Polish market, Coverager reported. The company offers a wide range of commercial insurance across Central and Eastern Europe…

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Oct 20 • 10:19 AM EDT • Business • businessinsurance.com
Green Science Alliance opens Swiss battery recycling lab

The Japanese chemical and greentech firm has opened a battery recycling laboratory at the Switzerland Innovation Park Biel/Bienne (SIPBB) in the canton of

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Oct 20 • 10:00 AM EDT • Science • electrive.com
Morning 3: Lincoln County home health worker accused of taking thousands in forged checks -- and other news

Here are the top stories for the morning of Oct. 20, 2026

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Oct 20 • 9:59 AM EDT • Health • wbtv.com
Codie Sanchez Says a 2-Week Vacation Reveals Whether You Own a Business or Just Work for One. I Disappeared for a Year. Here's What Happened

Two weeks tells you about your systems. A year tells you about your people.

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Oct 20 • 9:56 AM EDT • Business • inc.com
Home health worker accused of taking thousands in forged checks in Lincoln County

The employee allegedly took checks from a checkbook while providing care at a patient’s house.

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Oct 20 • 9:49 AM EDT • Health • wbtv.com
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HOMETOWN HEALTH: Researchers identify new clues for treating type 2 diabetes

The study's authors say this could be developed into new treatments that could help people regulate their blood sugar.

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Oct 20 • 9:33 AM EDT • Health • wdbj7.com
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Perot Museum Of Nature And Science Unveils $185 Million Expansion

The expanded campus is scheduled to open in late 2028

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Oct 20 • 9:30 AM EDT • Science • localprofile.com
Looted French goods are popping up on resale site Vinted

The second-hand online marketplace Vinted has removed listings of looted French goods and stepped up checks on “suspicious” adverts, as the country’s authorities seek to prevent goods stolen during riots from being sold online.

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Oct 20 • 9:28 AM EDT • Business • cnn.com
Today’s Papers: Juventus faith in Spalletti, Milan in Krösche talks

La Gazzetta dello SportSpalletti on the edgeThe coach has lost his way at Juve: Faith for the time beingDisastrous start, no lifelines left. A nervous coach asks for clarifications from Bremer. The su...

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Oct 20 • 9:05 AM EDT • Sports • sports.yahoo.com
Chinese scientists find neurons may act as minicomputers to help decision-making

Researchers find evidence that suggests neural activity can guide the way the brain adapts to different sensory experiences.

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Oct 20 • 9:00 AM EDT • Science • scmp.com
Law & Order: College Basketball — How the NCAA's eligibility rules have created chaos before the season's even begun

As the college basketball season quickly approaches, many schools are still trying to fill out their rosters as they navigate legal challenges to NCAA eligibility rules.

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Oct 20 • 8:58 AM EDT • Sports • sports.yahoo.com
Indian scientists identify Martian analogue sites

Kerala researchers identify Martian analogue sites in Tamil Nadu and Atacama Desert via hydrous sulfates, aiding Mars paleoenvironments study.

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Oct 20 • 8:46 AM EDT • Science • thehindu.com
Zapata Quantum Adds Peter Shor and Three Scientists to Advisory Board

Zapata Quantum has appointed Peter Shor and three researchers to its advisory board, adding expertise in quantum algorithms, error correction

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Oct 20 • 8:31 AM EDT • Science • thequantuminsider.com
Beyond Moneyball: What the Milwaukee Brewers Can Teach Businesses About Teamwork

The Milwaukee Brewers’ sweep of the defending champion Los Angeles Dodgers stunned the baseball world. But the series also showed that assembling the biggest collection of stars isn’t the only path to success, says University of Delaware researcher Kyle Emich. The Brewers' run to the World Series – which continues this week against the Tampa Bay Rays – demonstrates how a team can combine its strengths, adapt to an opponent and operate as a system, Emich says. That same p

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Oct 20 • 8:30 AM EDT • Business • newswise.com
At $10,000, Would You Race To Buy This 1987 Chevy Sprint Turbo?

Known by many names, but rarely found in such mint condition.

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Oct 20 • 8:25 AM EDT • Technology • jalopnik.com
Dodgers notes: Shohei Ohtani and what might’ve been

As the baseball world prepares itself for a low-cost World Series, Dodgers fans might still be looking backwards at what might’ve been. Sonja Chen on MLB.com focuses on how the team managed Shohei Ohtani’s injuries, and what perhaps they might’ve done differently. “I haven’t been able to really come to grip in terms of what […]

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Oct 20 • 8:18 AM EDT • Sports • sports.yahoo.com
Start-Up Claims to Treat a Patient With A.I.-Created Viruses

Certain viruses attack bacteria and can sometimes clear antibiotic-resistant infections. Researchers said they had tailored a virus to attack one patient’s illness.

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Oct 20 • 8:07 AM EDT • Science • nytimes.com
Garmin launches Edge 1060 bike computer with voice control, alongside new Edge Explore computers and Tacx Nēra smart trainer

New Edge 1060 heads up trio of new computers and trainer refresh from Garmin

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Oct 20 • 8:03 AM EDT • Technology • bikeradar.com
AI is Changing Science: Here’s What Journalists Need to Know

Researchers are rapidly adopting AI for everything from data analysis to planning and executing entire research studies. Journalists will need to keep up. That means learning the basic principles, strengths, and weaknesses of the diverse technologies labeled as “AI”—and how to tell when using AI in science is actually noteworthy. Luckily for science reporters, knowing your beat well can help you cut through the hype.

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Oct 20 • 8:00 AM EDT • Science • theopennotebook.com
Spotify launches paid podcast memberships with perks beyond bonus content

Spotify's new paid memberships let podcasters offer fans exclusive perks, including ad-free listening, early access, and bonus content, while keeping 90% of the revenue.

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Oct 20 • 8:00 AM EDT • Technology • techcrunch.com
Rob Reiner almost helped Larry David with his unproduced screenplay but made this movie instead

The comedians had a decades-long friendship, which also helped Cheryl Hines lock in an Emmy-nominated role.

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Oct 20 • 8:00 AM EDT • Entertainment • yahoo.com
CAS collaborates with Microsoft to enable faster innovation in pharmaceutical, life sciences, and chemical industries

/PRNewswire/ -- CAS, a division of the American Chemical Society, today announced the availability of CAS Connections in Microsoft Copilot. The connector gives...

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Oct 20 • 8:00 AM EDT • Science • prnewswire.com
Scientists finally uncover why statins can cause muscle pain

Scientists have uncovered a surprising reason why statins, the widely prescribed cholesterol-lowering drugs that help prevent heart attacks and strokes, can sometimes cause muscle pain, weakness, and even severe muscle damage. Using advanced imaging technology, researchers discovered that statins can attach to a crucial protein in muscle cells and force open a channel that normally controls calcium flow. This causes calcium to leak continuously, potentially damaging muscle tissue.

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Oct 20 • 8:00 AM EDT • Science • sciencedaily.com
NBA games on TV today: Schedule, times, TV channels, live streams to watch every team's season opener

Basketball is finally back. Here's when and where to watch every team's season opener.

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Oct 20 • 7:58 AM EDT • Sports • sports.yahoo.com
Sponsored Content: HMG Health Matters: A Surgeon's Perspective on Breast Cancer

Dr. Cheryl Stanski, General Surgeon and Vice President of Holston Medical Group tells us what she wants every woman to know about breast cancer. She talks about the success rate, the hope, and the options now available for women. For more information and to read more please visit the Health Matters blog at HolstonMedicalGroup.com.

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Oct 20 • 7:47 AM EDT • Health • wjhl.com
Matthijs De Ligt Handed Starting Chance vs Como As Man Utd Dealt Blow

Manchester United travel to Italy this afternoon ahead of their third Champions League tie against Como.

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Oct 20 • 7:43 AM EDT • Sports • sports.yahoo.com
Woman Indicted In Alleged $612,000 Theft Scheme From Great Mills Business

GREAT MILLS, Md. — An Odenton woman has been indicted on six theft charges after prosecutors alleged she stole approximately $612,758.92 from a Great Mills business through unauthorized payments and credit card transactions spanning several years. Heather Lynne Payton, 50, was indicted by a St. Mary’s County grand jury on September 28, 2026, in connection […]

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Oct 20 • 7:39 AM EDT • Business • thebaynet.com
Ten Hag opens up on Ronaldo fallout at Man Utd

Erik Ten Hag has opened up about his fractured relationship with Cristiano Ronaldo during his time at Manchester United, claiming the Portuguese forward was not prepared to meet the physical demands o...

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Oct 20 • 7:22 AM EDT • Sports • sports.yahoo.com
UConn Researcher’s Insight on Small-Business Bankruptcy Recovery Draws the Attention of Congress

'Small businesses are an important part of the economy, but financial distress does not necessarily mean that the underlying business isn’t worthwhile& ...

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Oct 20 • 7:20 AM EDT • Business • today.uconn.edu
Pet costume parade coming soon to NewBo City Market

Howl-O-Ween Pet Costume Parade coming to NewBo City Market on Oct. 24. Also, “Candles & Classics” at Orchestra Iowa, Cedar Rapids museum hosts artists market, Iowa City chorus honored, and Clermont concert highlights historic pipe organ.

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Oct 20 • 7:00 AM EDT • Entertainment • thegazette.com
'We used to go to the climate conferences together. We are not anymore': ESA official Simonetta Cheli tells us how the political landscape for Earth observation is changing

Live Science sat down with the European Space Agency's Simonetta Cheli to discuss the importance of Earth observation, how NASA budget cuts have changed the picture, and how the proliferation of private satellites could hinder our ability to view the planet.

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Oct 20 • 7:00 AM EDT • Science • livescience.com
San Marcos relaunches support program for local businesses

The city of San Marcos re-launched its SMTX BOOST program to provide local small businesses with free training, coaching and resources.

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Oct 20 • 7:00 AM EDT • Business • communityimpact.com
A note to readers: Science, accountability and elections

Dear readers, As early voting begins, I wanted to share some news — and why it connects to the decisions we make at the ballot box. I’ve been selected for the inaugural cohort of the South Atlantic Climate Journalism Hub mentorship program, hosted by Covering Climate Now. I’m excited to join this group, learn from scientists and fellow journalists, and expand my science reporting. Science directly ties to governance. Local officials make decisions about where development goes, how infrastructure is maintained, what emergency preparations receive funding, and how communities rebuild after disasters. Understanding the evidence behind those decisions helps us evaluate whether our government is serving us well. Here in western North Carolina, those connections are all around us, in Lake Lure and beyond. Flood maps inform decisions about property and development. Engineering assessments help identify risks at dams and bridges. Rainfall forecasts guide emergency preparations. Geological information helps explain landslide hazards. Water testing gives communities information they need to assess conditions. Meteorologists’ knowledge and public perception of weather events shape public safety. Each involves scientific or technical knowledge. Each also raises questions about public responsibility: What did officials know? How did they use that information? What did they tell the public? What did taxpayers receive for their money? A study can identify a problem. Elected officials still have to decide what to do about it, how to pay for it, and how to explain their choices. Reporting should examine both the evidence and the response. That is where I want to strengthen my work. My reporting on Helene recovery, infrastructure, flooding, public safety, and public spending has repeatedly brought me to questions that require scientific expertise alongside public records. This mentorship may help me better understand the research, ask more precise questions, and explain the answers clearly. I also bring the perspective of someone living with these concerns. I live downstream of Lake Lure Dam, and landslides affected my property during Helene. Those experiences bring urgency to my questions. Careful reporting helps establish the answers. Readers deserve to know what the evidence shows, where uncertainty remains, and whether officials accurately describe the information guiding their decisions. You also deserve scrutiny of proposed solutions: what they cost, what they are expected to accomplish, and what risks remain. Access to that information matters. As a mostly deaf journalist who relies on written communication, I will continue pressing for written public warnings, records, and explanations that people can read and use in real time. As you consider the candidates seeking your vote, consider how they approach evidence, preparedness, and transparency. Do they support local journalism, even when it’s not parroting a press release? Do they explain weather events clearly in plain English and explain their decisions after them? Make supporting records available? Acknowledge uncertainty? Follow through when a report identifies a risk? Those are practical questions about governing. Thank you for supporting Cops & Congress and the work that makes these questions part of the public conversation. I’m grateful to David Dickson and the CC Now team for this opportunity, and I look forward to bringing what I learn back to you. Annie DanceEditor & Publisher, Cops & Congress — Learn more about this newsletter, ethics policy, how you can help shape this work, and support it. Follow on X and Facebook. Send constructive criticism, fan mail, and tips with public documents for future stories: CopsandCongress@gmail.com ICYMI: View the Cops & Congress archive — Annie Dance is the publisher of Cops & Congress, a newsletter that analyzes what happens when crime, courts, disaster, democracy, and small-town policies collide. Views expressed here are covered by the First Amendment. Dance has a Bachelor of Arts from Manhattan University in Communication with a focus in Journalism and Government. She has been a journalist for over 20 years. Share Upgrade now or give a gift subscription

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Oct 20 • 6:56 AM EDT • Science • anniedance.substack.com
How an acclaimed opera singer became Providence’s Bride of Cthulhu

What happens when an opera singer/organist/conductor meets Lovecraft? You get Gigi Mitchell-Velasco, a consummate performer and Bride of Cthulhu.

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Oct 20 • 6:09 AM EDT • Entertainment • providencejournal.com
Owner of CT information technology consulting business sentenced for computer intrusion scheme

Federal officials said he remotely disabled a client’s computer network on 21 separate days in 2024, which resulted in the company being unable to conduct business on those days.

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Oct 20 • 5:45 AM EDT • Business • courant.com
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List of DVD release dates for Oct. 20 and beyond

Following is a partial schedule of coming movies on DVD. Release dates are subject to change: OCTOBER 20: Masters of the Universe 20: Hadestown: The Musical 20: One Night Only

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Oct 20 • 5:45 AM EDT • Entertainment • recorderonline.com
The Kardashian personal chef reveals celebs' top requests

Khristianne Uy, best known as Chef K, has built a career in the celebrity-sphere cooking for major names like Justin Bieber, Salma Hayek, Ryan Seacrest and — most notably —

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Oct 20 • 5:41 AM EDT • Entertainment • centraloregondaily.com
Why Calling Anti-Trans Hate a “Distraction” Is So Troubling

It’s a familiar line in the midterms: Anti-trans attacks are a “distraction” from “kitchen-table” issues. That sends a chilling message about whose rights are worth fighting for.

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Oct 20 • 5:30 AM EDT • Politics • thenation.com
Where to watch Tennessee-Duke basketball: TV, channel, streaming

Tennessee basketball will play Duke on Tuesday. Here is how to watch, including time, channel, TV schedule and streaming info.

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Oct 20 • 5:04 AM EDT • Sports • sports.yahoo.com
Vivek Ramaswamy gets a political education in a grueling Ohio governor’s race

Vivek is attempting a rare route in politics, going from national notoriety as a presidential candidate to running for state office, eschewing his hard-charging and provocative tone during his presidential campaign. He’s making his pivot during an election cycle where headwinds are blowing against all kinds of Republicans. It hasn’t been easy.

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Oct 20 • 5:00 AM EDT • Politics • cnn.com
Yankees news: Teruaki Sato will officially be posted

Sato will officially be posted this offseason; Boone returns as skipper for 2027; Wells identifies foul tips as potential cause of headaches.

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Oct 20 • 5:00 AM EDT • Sports • sports.yahoo.com
What to eat for younger-looking skin

Plants, fats, and fermented foods can reduce wrinkles, boost collagen and improve the texture of our skin.

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Oct 20 • 4:45 AM EDT • Technology • bbc.com
Manchester United and Liverpool battling for Borussia Dortmund star

Manchester United and Liverpool are both considering a move for Borussia Dortmund midfielder Felix Nmecha, according to TEAMtalk.The report suggests that Manchester United have made contact as they as...

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Oct 20 • 4:19 AM EDT • Sports • sports.yahoo.com
PREVIEW: Wolves face Portsmouth for the first time since 2010

Portsmouth will travel to Molineux on Tuesday evening for the first time in 17 years to face Wolves in a rescheduled Championship fixture.With a game in hand, a win for Cesar Peixoto’s side will see...

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Oct 20 • 4:15 AM EDT • Sports • sports.yahoo.com
Pfizer makes ‘business decision’ to end phase 2 trial of autoimmune drug as program’s future uncertain

Pfizer has called time on a phase 2 trial of its CXCR5 antibody in an autoimmune blood disorder, with the company tight-lipped on whether this marks the end of the road for the asset. The Big Pharma had been evaluating the therapy, dubbed PF-06835375, in a phase 2 study of 61 patients with primary immune thrombocytopenia (ITP) that kicked off in 2022, according to the federal trials register. However, Pfizer confirmed to Fierce on Monday that this study had been terminated “due to a business decision.” “The decision to terminate the trial was not based on any safety concerns,” a spokesperson pointed out. At time of publication, PF-06835375 remained listed on Pfizer’s website for both ITP and lupus. A phase 1 study in lupus wrapped up in 2022, according to the trials database. ITP is an autoimmune disorder characterized by a low platelet count. Novartis was at one point evaluating its B-cell-depleting antibody ianalumab—recently approved as Fabhalta to treat immunoglobulin A nephropathy—as a potential treatment ITP. But the therapy struggled to demonstrate a benefit in the clinic for this indication. When contacted by Fierce, Pfizer wouldn’t confirm whether all work on PF-06835375 has been halted, and whether the company has any other plans to explore C-X-C chemokine receptor type 5 (CXCR5) as a mechanism. CXCR5 is found in blood cancers such as diffuse large B-cell lymphoma and mantle cell lymphoma chemokine receptor. However, there is little expression in normal tissue, which has led some drug developers to explore its potential. Vincerx Pharma had at one point been planning to take an anti-CXCR5 ADC into the clinic to treat B-cell malignancies, but that ambition was scrapped due to cash constraints. Where Big Pharma is placing its bets is one of the hot topics being discussed at Fierce Biotech's high-impact event in London next month. Find out more information and register by clicking on the banner below: [ ](https://qtxasset.com/quartz/qcloud5/media/image/where_big_pharma_is_placing_its_bets.png?VersionId=B8JrRbJ.pFUSK1pJgjeWHLGm_18RdLAy)

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Oct 20 • 3:59 AM EDT • Business • fiercebiotech.com
GLP-1 drugs may protect kidney health in people with bipolar disorder

Mayo Clinic researchers found that GLP-1 receptor agonists, medications widely used for diabetes and weight management, were associated with a lower risk of dialysis or kidney transplantation in adults with bipolar disorder and chronic kidney disease.

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Oct 20 • 3:41 AM EDT • Health • news-medical.net
Sanford Health CEO Bill Gassen talks about merger with North Memorial
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Oct 20 • 3:13 AM EDT • Health • chiefhealthcareexecutive.com
The best quotes about Eric Cantona

Eric Cantona remains one of the Premier League's most impactful footballers. Cantona was the signing that proved to be the catalyst behind Manchester United's dominance of the division, helping break ...

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Oct 20 • 3:10 AM EDT • Sports • sports.yahoo.com
Roland unveils a new Jupiter-8-inspired Boutique synth in celebration of the original's 45th birthday – and drops an all-new wavetable synth too

A pint-sized take on the '80s classic, the Jupiter-08 launches alongside the N/vision, a wavetable synth that promises "rich tonalities, evolving textures and sophisticated sound design"

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Oct 20 • 3:00 AM EDT • Technology • musicradar.com
WEBTOON Entertainment Inc. (WBTN) - What Are Researchers Saying About This Stock?

WEBTOON Entertainment Inc. (NASDAQ:WBTN - Get Free Report) has earned an average rating of "Hold" from the seven analysts that are presently covering the firm, MarketBeat reports. One analyst has rated the stock with a sell recommendation, five have issued a hold recommendation and one has issued a

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Oct 20 • 2:14 AM EDT • Entertainment • marketbeat.com
Michel Sanchez Provides Injury Update On Ajax Defender Daley Blind

Michel Sanchez has revealed that Daley Blind is nearing a return to action.

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Oct 20 • 1:30 AM EDT • Sports • sports.yahoo.com
Franciscan Health Dyer adds OrderAhead food locker in partnership with Food Bank of NWI

Technology enhances partnership aimed at fighting Region food insecurity DYER, Ind. – Franciscan Health Dyer now has an OrderAhead food locker thanks to a partnership with the Food Bank of Northwest Indiana and generous donations to the Franciscan Health Foundation. The OrderAhead food locker program was designed by the Food Bank of Northwest Indiana for neighbors with chronic concerns about adequate food access. The lockers allow food-insecure individuals to place an order online for pickup at a scheduled time. “We are thankful to be able to further enhance our impactful partnership with the Food Bank with the addition of the

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Oct 20 • 1:15 AM EDT • Health • wimsradio.com
Scene

In this week’s scene, we find this skeletal fellow who has found a garbage can of toxic waste recently spotted in front of a Winchester home.

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Oct 20 • 1:15 AM EDT • Entertainment • winchesternewsgazette.com
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Bristol breakthrough could transform science for blind people

A Bristol-made device displays complex data in braille, helping blind people study and work in STEM.

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Oct 20 • 1:14 AM EDT • Science • bbc.com
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Hospital mergers in Minnesota: What’s driving deals
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Oct 20 • 12:11 AM EDT • Health • chiefhealthcareexecutive.com
Japan launches historic mission to bring back Mars moon samples
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Oct 20 • 12:08 AM EDT • Science • aljazeera.com
Manchester City vs AEK Athens – Predicted lineup and team news

Manchester City are expected to rotate against AEK Athens on Tuesday, with Erling Haaland likely to be rested and Antoine Semenyo out for around eight weeks.City lost 4-2 at home to Paris Saint-Germai...

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Oct 20 • 12:00 AM EDT • Sports • sports.yahoo.com
Bruins Nikita Zadorov Felt “Disgusted” By Being Scratched

Boston Bruins head coach Marco Sturm decided to send a message of tough love to bruising defenseman Nikita Zadorov when he designated him as a healthy scratch for their recent outing, a 4-1 victory on the road over the struggling Los Angeles Kings.Zadorov had been whistled for a penalty in their previous game against the […] The post Bruins Nikita Zadorov Felt “Disgusted” By Being Scratched appeared first on HEAVY.

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Oct 19 • 11:50 PM EDT • Sports • sports.yahoo.com
5 Cheaper OLED TVs To Buy Instead Of The Samsung S95H

While the Samsung S95H is an excellent OLED TV, it can get pricey, depending on the size you pick. Here are some affordable alternatives from other brands.

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Oct 19 • 11:17 PM EDT • Technology • bgr.com
Seminoles Mourn the Passing of Former Coach Chuck Amato

He was a fixture on the Florida State sideline for 27 years, and coached many of the program's greatest defensive stars, like Derrick Brooks and Corey Simon. to name a few.

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Oct 19 • 11:15 PM EDT • Sports • sports.yahoo.com
World Series 2026: Schedule, broadcast and start times for Rays vs. Brewers
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Oct 19 • 11:10 PM EDT • Sports • sports.yahoo.com
Rays Clinch Pennant, Head to Small-Market World Series

The Rays clinched their third American League pennant.

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Oct 19 • 11:04 PM EDT • Sports • sports.yahoo.com
Scientists found 2 ways to destroy 'forever chemicals,' and 'forever' may not mean forever

The video says PFAS "barely break down in nature" and can remain for decades or even centuries.

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Oct 19 • 10:25 PM EDT • Science • yahoo.com
ACHE’s new rural-focused public health doctoral program welcomes first class of 21

A new doctoral program at the Arkansas Colleges of Health Education in Fort Smith aims to equip healthcare professionals with skills to address rural health disparities and revive services missing from their communities.

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Oct 19 • 10:10 PM EDT • Health • arkansasonline.com