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Xbox Boss Reveals New 'Dedicated Team' Focusing On Fan Feedback
Following the rollout of new achievement features
Xbox Achievements are getting some major changes, including the option to hide embarrassing games that you don't want to show off
Xbox is changing the achievement system, allowing for visual customization, hiding specific games, and highlighting others.
Leaders Across Sports, Business and Higher Education Affirm the Value of Academics in College Football
IRVING, Texas (April 9, 2026) – As the National Football Foundation marks 20 years of the NFF Hampshire Honor Society and a record-setting 2026 class, leaders from the highest levels of sports, business and higher education are praising the organization's role in elevating academic achievement as a core part of the game. Their perspectives reinforce the Foundation's long-standing commitment to ensuring education remains central to the student-athlete experience.
Leaders Across Sports, Business and Higher Education Affirm the Value of Academics in College Football
IRVING, Texas (April 9, 2026) – As the National Football Foundation marks 20 years of the NFF Hampshire Honor Society and a record-setting 2026 class, leaders from the highest levels of sports, business and higher education are praising the organization's role in elevating academic achievement as a core part of the game. Their perspectives reinforce the Foundation's long-standing commitment to ensuring education remains central to the student-athlete experience.
Xbox Achievements Get Overdue Update To Address Feedback
It's one of a number of features the platform is spiffing up to address fan feedback
College of Health Professions’ Audiology Program Achieves No. 18 in Country
The Doctor of Audiology (AuD) program at the University of Tennessee Health Sciences ranked No. 18 in the nation in U.S. News & World Report.
BYU-Idaho Students Accepted to Health Professional Schools at Above-Average Rates
BYU-Idaho students applying to professional health programs during the 2024–2025 cycle achieved high acceptance rates to various medical schools.
Comptroller Review Finds City's Small Business Forward Program Failed to Cut Red Tape or Limit Fines
New York, NY — A new review conducted by auditors of New York City Comptroller Mark Levine found the Small Business Forward program, aimed at easing regulatory and financial burdens on small businesses across the five boroughs, failed to achieve meaningful change for small businesses in New York City. Vague definitions, a lack...
Xbox Achievements Are Getting A 'Refresh' With Multiple New Improvements
"We’re excited to hear what you think"
Healthy Impact
In recognition of decades of leadership, innovation and statewide impact advancing nutrition education and healthier communities, Carolyn Dunn received the Lifetime Achievement Award from the Association of Public and Land-grant Universities’ Board on Health and Human Sciences.
UNE faculty, business executive board mentor high schoolers in regional workforce development challenge
Students from multiple high schools in southern Maine gathered on April 2 to compete at the University of New England in the Junior Achievement of Maine’s (JA Maine) Titan Challenge, and several teams were mentored by faculty in UNE's College of Business — including the winning team in the southern Maine region.
World Health Day 2026: Together for health. Stand with science
On World Health Day 2026, celebrated on 7 April, WHO unites and mobilizes the world under the theme “Together for health. Stand with science.” celebrating the power of scientific collaboration to protect the health of people, animals, plants, and the planet. The year‑long campaign spotlights both scientific achievements and the multilateral cooperation needed to turn evidence into action.
2026 Distinguished Lecture Series in Materials Science and Engineering
The Distinguished Lecture Series in Materials Science and Engineering at Penn State will be held in April and will include two Richard E. Tressler Award Lectures in Materials and the David Ford McFarland Award Lecture for Achievement in Metallurgy.
3 Things to Know: Brands and Social Issues, Adult Recreational Sports League Participation Rebounds, and Sports Betting Partnerships
CivicScience has the world’s largest proprietary database of real-time declared intent, allowing brands to activate high-performing advertising that drives up to 80% better performance. See how our partners achieve superior marketing outcomes here. 1. Consumers hold mixed expectations on brand activism, with Democrats more likely to switch or boycott based on personal values, while Republicans [...]Read More... from 3 Things to Know: Brands and Social Issues, Adult Recreational Sports League Participation Rebounds, and Sports Betting Partnerships
Cincinnati Business Achievement Awards celebrates past, present and future
The Cincinnati Business Achievement Awards (CBAAs) recognized honorees at the Renaissance Cincinnati Downtown on Thursday, March 5, welcoming hundreds of members of the region’s business community.
College Notes: Athletes with Upper Valley ties compete in winter sports
Discover the achievements of Upper Valley residents in collegiate varsity sports this winter, from basketball to skiing.
Preview: Colorado aiming to clinch West against St. Louis
How many milestones will be achieved tonight?
School news: Pine Tree math, science team wins state competition - Longview News-Journal
The latest news on student achievements, school programs and more at Longview-area districts
IPL 2026: Abhishek Sharma scripts history, joins David Warner to....
Abhishek Sharma achieved a significant milestone for Sunrisers Hyderabad, becoming the second player to hit 100 sixes for the franchise. SRH secured their first IPL 2026 win by defeating Kolkata Knight Riders by 65 runs, defending a season-high total of 226/8 with a strong bowling performance.
Pepperdine Graziadio Business School Announces Physician and Innovator Martha Molina Bernadett (MBA '01, PKE 105) as Distinguished Alumnus Award Recipient
Recognized for her outstanding personal and professional achievements as a healthcare professional, Bernadett currently serves as a University Board member and has been previously recognized with the Waves of Service George Award and as an Outstanding Alumni in Healthcare.
PlayStation Acquires Machine Learning Specialist to Achieve 'New Levels' of Game Visuals
Cinemersive Labs
Sport Excellence Award Recipients Announced for Winter
NORTH ATTLEBORO, Mass. – The Northeast 10 Conference recognized seven student-athletes from the winter season as Sport Excellence Award winners on Thursday afternoon, honoring their outstanding athletic and academic achievements.
A year after 'Liberation Day,' what did Trump’s tariffs achieve?
President Trump announced worldwide tariffs a year ago. He later lost at the Supreme Court, prompting the administration to look for ways to bypass the high court.
Business Ownership in Europe: The McDonald’s Model
Discover how franchising with McDonald’s helps entrepreneurs in Europe achieve business ownership, drive growth and support local communities.
Remembrance: Former colleagues praise Barry Bloom’s scientific achievements, global health contributions, and good humor | Harvard T.H. Chan School of Public Health
Barry Bloom, the former dean of Harvard Chan School who died on March 18, was an inspiration to many, according to longtime colleagues Marc Lipsitch and Yonatan Grad.
PC Game Pass adds Heroes of Might and Magic: Olden Era later this month
Developer Unfrozen and publisher Hooded Horse have announced that their strategy game Heroes of Might and Magic: Olden Era will join PC Game Pass in April.
A Global Business Leader Shares His Philosophy For Fulfillment Beyond Material Achievement In New Book
“Be Your Own Sultan: The Transformative Power of Redefining Wealth” by Sultan Sobhi Batterjee is released with Forbes Books.
MCC students awarded for 1986 science fair achievements
MCC junior high science fair award winners in March 1986 were Mike Fischer, Terry Kosiboski, Craig Harless, Julie Fischer, Stacey Swiatlowski, Heather Adamczak and Kim Nowak.
Scientists achieve ‘impossible’ solar efficiency in renewables breakthrough
‘Spin-flip’ technique promises to shatter efficiency limits
Stephen Safe chosen for 2026 SEC Faculty Achievement Award
The work of Stephen Safe has led to many accolades, most recently as a winner of the 2026 Southeastern Conference, SEC, Faculty Achievement award.
A decade of impact in maternal and child health
As we celebrate 10 years of giving, we are proud of what donors and partners have achieved to decrease maternal and infant deaths.
The Long Dark returns to Xbox Game Pass today
Survival fans are in for a treat today, as Hinterland's fantastic The Long Dark returns to Xbox Game Pass for console, PC, and handheld.
Jorge Martin comeback win earns praise from fellow world champions
Both Francesco Bagnaia and Fabio Quartararo underlined the magnitude of what Martin achieved at COTA on Saturday
Chris Kelly Opinion: A petition for better acting in politics and PR
“Memory, all alone in the moonlight/ I can dream of the old days/ Life was beautiful then…” – from “Memory,” by Andrew Lloyd Webber Successful theatrical productions achieve the “suspension of disbelief,” temporarily convincing audiences th…
Xbox gets over 20 new games next week
Over the next seven days, a wave of 21 new Xbox games, including Super Meat Boy 3D and Darwin's Paradox, launch across Xbox consoles and PC.
Bayern honour Asian Cup champion Tanikawa
Newly crowned Asian Cup winner Momoko Tanikawa was honoured for her achievement by FC Bayern Women director Bianca Rech ahead of the team’s Bundesliga game at home to Nürnberg on Saturday. The Baye...
Poll: What were your favorite announcements at the Xbox Partner Preview 2026?
Microsoft's recent showcase gave us a plethora of Game Pass games to look forward to, so for this week's poll, we want to know: What were your favorite announcements at the Xbox Partner Preview 2026?
First full logical operations achieved on silicon quantum chip
Silicon quantum chip performs error-checked operations, marking a step toward fault-tolerant quantum computing.
Vanderbilt Lung Transplant Program sets new record
The Vanderbilt Transplant Center is now the second largest lung transplant center in the United States by volume, with 149 lung transplants in 2025, the most ever in one year at Vanderbilt Health. The Vanderbilt Lung Transplant Program leads the nation in organ preservation and regeneration and is among the best in long-term outcomes, demonstrating the success of the interdisciplinary team in caring for these complex patients. Several features make the program unique in the United States, said Konrad Hoetzenecker, MD, PhD, professor of Thoracic Surgery and surgical director of the Vanderbilt Lung Transplant Program. Vanderbilt serves as a “second opinion center” and accepts most complex candidates that are turned down by other centers due to increased perioperative risk. This includes patients over 70 years old, patients requiring combined procedures with their transplant, multiorgan transplantations and sensitized patients (individuals who have pre-formed anti-HLA antibodies who are at higher risk for complications). The expertise and excellent outcomes have attracted patients far beyond the borders of Tennessee; almost half of Vanderbilt Health’s lung transplant recipients come from out of state. “Another unique feature is our minimally invasive transplant program,” Hoetzenecker said. “By using distinct surgical instruments and techniques, the incisions can be kept as small as 7 to 8 centimeters, which results in better healing, less pain and faster recovery. “This minimally invasive approach is embedded in an Enhanced Recovery After Surgery (ERAS) protocol, a multimodal, evidence-based perioperative care pathway designed to reduce surgical stress, minimize complications and speed up recovery. Our unique ERAS protocol, by a dedicated interdisciplinary approach, aims to improve recovery after lung transplant and reduce ICU and hospital stay.” The lung transplant program recently celebrated a milestone — 1,000 lung transplants since the program began in 1990. “This significant achievement reflects the concerted effort of a multidisciplinary collaboration by the Departments of Thoracic Surgery, Medicine, Anesthesiology and Critical Care,” said David Erasmus, MD, associate professor of Medicine and medical director of Vanderbilt Lung Transplant. Lung transplants have been attempted since the 1960s, but they were largely unsuccessful until the 1980s, when surgical techniques were refined and new antirejection drugs proved effective. Patient outcomes steadily improved from the 1990s to the present. Vanderbilt’s fourth lung transplant recipient in 1990, Pam Everett, is the longest-living, single-lung transplant known in the world, recently celebrating 35 years since her transplant. The Vanderbilt Lung Transplant surgical team is led by Hoetzenecker and Caitlin Demarest, MD, PhD, the surgical director and associate surgical director of the Vanderbilt Lung Transplant program. Erasmus is the medical director of Vanderbilt Lung Transplant along with Anil Trindade, MD, associate medical director and associate professor of Medicine.
UABTeach Program Achieves Record Retention and Largest Math & Science Teaching Cohort - Alabama Department of Labor
FOR IMMEDIATE RELEASE March 26, 2026 BIRMINGHAM, Ala. – The UABTeach program at the University of Alabama at Birmingham, supported by The Alabama STEM Council via the Alabama Department of Workforce, is reporting strong student retention with a record number of STEM majors progressing toward graduation with the additional bonus of earning their teacher certifications. […]
2025 American Association for the Advancement of Science (AAAS) Fellow
Department Chair, Professor Alexander Spokoyny has been selected as a 2025 Fellow of the American Association for the Advancement of Science (AAAS) in recognition of his distinguished contributions in main group and organometallic chemistry and academic community engagement and leadership. AAAS is the world’s largest general-scientific society and publisher of the journal Science. Spokoyny is among the 449 scientists, engineers, and innovators spanning 24 scientific disciplines who are being recognized for their scientifically and socially distinguished achievements. Four of the new fellows are UCLA faculty members. The new Fellows will be celebrated in Washington, D.C., in late May 2026. Read more about the new AAAS Fellows here. AAAS Fellows in the UCLA Department of Chemistry & Biochemistry are Professors Kendall Houk (1988), Paul Weiss (1999), Richard Kaner (2000), David Eisenberg and Todd Yeates (2001), Juli Feigon (2002), Miguel Garcia-Garibay and Steven Clarke (2007), Heather Maynard, Carla Koehler, Xiangfeng Duan and Neil Garg (2018), Paula Diaconescu and Thomas Mason (2019), Joseph Loo (2021), and Yi Tang (2022). Penny Jennings, UCLA Department of Chemistry & Biochemistry, penjen@g.ucla.edu.
Ten Johns Hopkins researchers named American Association for the Advancement of Science Fellows
The 2025 class of American Association for the Advancement of Science fellows includes 449 scientists, engineers, and innovators spanning 24 scientific disciplines who are being recognized for their scientifically and socially distinguished achievements
Samsung Reportedly Drops Plans To Design Its Exynos 2800 On A Sub-2nm Process, Preferring Healthy Yields And Optimizations Over Cutting-Edge Lithography
Rather than raise unnecessary production costs, the Exynos 2800 will utilize Samsung’s new 2nm process to achieve better yields and optimizations
Award-winning podcasts bring Susquehanna’s stories — and science — to life
Stay up to date with the latest news, stories, and achievements from the Susquehanna University community.
Student-led business hooks customers across the country
Stay up to date with the latest news, stories, and achievements from the Susquehanna University community.
RPI Athletics Celebrates 50 Years of Women's Sports
Rensselaer Polytechnic Institute proudly celebrates 50 years of women's varsity athletics—a milestone that reflects decades of progress, achievement, and opportunity for generations of student-athletes. What began as a commitment to expanding access in intercollegiate athletics has grown into a vibrant and competitive tradition that continues to shape the RPI community today.
SW FL Business Hall of Fame honors four new leaders. Read about them
Junior Achievement of Southwest Florida inducted four new laureates into its Business Hall of Fame on March 24.
SW FL Business Hall of Fame honors four new leaders. Read about them
Junior Achievement of Southwest Florida inducted four new laureates into its Business Hall of Fame on March 24.
IPS Students Showcase Data Science Skills with Pascal Siakam at Arsenal Tech
Pascal Siakam of the Indiana Pacers will visit Indianapolis Public Schools (IPS) on Thursdaay, March 26 to celebrate student achievements in the ‘Data Dunkers’ program. Driven by a partnership between the PS43 Foundation and Dell Technologies, this initiative leverages basketball to teach foundational STEM and data analysis skills. During the event, Siakam will meet with… Read More »IPS Students Showcase Data Science Skills with Pascal Siakam at Arsenal Tech
WATCH: 'We negotiate with bombs,' Hegseth says of U.S. air campaign in Iran
President Donald Trump has listed five objectives that the U.S. wants to achieve before ending its war with Iran. Now, as he suggests the U.S. may soon be “winding down” the operation after three and a half weeks, some of his key aims remain undefined or unfulfilled.
Maine governor candidate King sets education priorities
King said he wants to help teachers by simplifying what it takes to be certified, rewarding high achievers with better pay and giving them opportunities to further their careers.
Minecraft's Tiny Takeover update arrives today with cuter animals and new items
Minecraft's first major 'game drop' of 2026, Tiny Takeover, arrives today, introducing 39 redesigned baby mobs to the game, as well as a few new items.
Susquehanna business school ranks No. 3 nationally for academic experience in debut on Poets&Quants
Stay up to date with the latest news, stories, and achievements from the Susquehanna University community.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Particle Breakthrough: South Dakota scientists help unlock new neutrino mystery
Scientists at South Dakota Mines help achieve the first-ever measurement of a rare neutrino interaction, advancing physics and supporting future research at SURF.
Agnes Pockels’ pioneering work was unfairly dismissed by tropes about women’s domestic roles
Agnes Pockels achievements in surface science have long been overshadowed by a popular and likely untrue story that she became interested in the subject while doing the dishes
Babson Taps Multigenerational Business Leaders for 2026 Commencement Addresses
CEO and Executive Chairman of Metropoulos & Co. C. Dean Metropoulos '67, MBA'68, will give the undergraduate Commencement address, with Cisneros CEO Adriana Cisneros speaking at the graduate Commencement ceremony.Wellesley, Massachusetts--(Newsfile Corp. - March 19, 2026) - Babson College will honor the achievements of more than 740 undergraduate and 540 graduate members of the Class of 2026 before thousands of family members, faculty, friends, colleagues, and peers in separate on-campus...
German Health Minister Nina Warken and WHO Hub in Berlin highlight 2025 achievements
Germany’s Federal Minister of Health, Nina Warken, visited the WHO Hub for Pandemic and Epidemic Intelligence in Berlin today to review progress and launch its 2025 Annual Report. The report highlights advances in using artificial intelligence, data science and pathogen genomics to strengthen global preparedness for future pandemics.In 2025, the WHO Hub in Berlin worked with more than 160 Member States and over 190 partners to help countries and organizations develop new systems and tools to detect and understand new public health threats as quickly as possible, whenever and wherever they occur.BMG to confirm whether they wish to contribute a quote. “Detecting outbreaks early is one of the most effective ways to save lives and prevent epidemics from becoming global crises,” said Federal Minister of Health Nina Warken. “Germany is proud to host and support the WHO Hub for Pandemic and Epidemic Intelligence. Its work strengthens our safety at home and helps protect people worldwide.”Artificial intelligence is increasingly transforming the detection of outbreaks. In 2025, the Hub launched an upgraded version of the Epidemic Intelligence from Open Sources (EIOS) system, which uses enhanced AI functions to scan global online information in real time and help experts quickly identify unusual health events. The system is now used by 120 countries.To better anticipate health threats, countries need information beyond traditional health data. The Hub supports countries in implementing Collaborative Surveillance, which integrates data on climate, animals, travel, and population movement to provide a more comprehensive and real-time understanding of health threats.The Hub also expanded global access to pathogen genomics, which helps scientists detect new pathogens, such as viruses and bacteria, understand how they spread and how dangerous they may become. Through the International Pathogen Surveillance Network (IPSN), the WHO Hub in Berlin worked with 309 partners in 101 countries to expand access to these technologies.“We are in a new era of global health threats, and we need new tools to face tomorrow’s challenges,” said Dr Chikwe Ihekweazu, Executive Director of the WHO Health Emergencies Programme. “The WHO Hub in Berlin helps countries use data and technology more effectively so they can identify risks earlier and respond faster. No country can address these threats alone. Strong cooperation remains our best defence.”“Berlin offers an ideal environment for our work. We collaborate closely with world-leading institutions such as the Robert Koch Institute and the Charité Center for Global Health,” said Dr Oliver Morgan, Head of the WHO Hub for Pandemic and Epidemic Intelligence. “Germany has supported the WHO Hub since its establishment, and we are pleased to welcome Federal Minister Nina Warken to the Hub today. This strong partnership helps us advance innovation in pandemic and epidemic intelligence and better support countries to prepare for future health threats.”The Hub is expanding the use of advanced analytics and mathematical modelling to forecast how outbreaks may develop and to assess which response measures are most effective. Through its Collaboratory, the Hub connects modelers and analysts with governments to ensure their work addresses real public health needs. In 2025, the community grew to 1300 members from 50 countries and 200 institutions. An AI-powered pandemic simulator, currently in the prototyping phase, will help decision-makers compare outbreak scenarios and help identify effective disease control measures.
Women in Medicine and Science Research Day Highlights Achievements and Opportunities
The 20th annual Women in Medicine & Science Research Day on March 11 offered opportunities for community-building, networking, mentoring and collaboration.
Pikl Pioneers a New Category of Insurance-Enabled Business Models, Earning it 20% UK Short-Term Rental Market Share
Pikl, the company pioneering insurance-enabled business models that drive revenue whilst protecting against downside risk, today announced that it has achieved 20% market share in the UK short-term rental market – the first industry in which its insurance-enabled growth solutions have been delivered. The achievement comes just two years after Pikl launched its flagship flexible cancellation solution in 2024, which allows property management companies (PMCs) to offer guests the flexible booking o
XOMA Royalty Reports 2025 Financial Results and Highlights Recent Business Achievements
Portfolio receipts: • Achieved over $50 million of cash receipts, including $33.6 million in royalties and $16.9 million milestones, in full year 2025 • Total receipts increased 9% with royalties up 68% versus full year 2024 Business development: Added 22 assets to portfolio, including five programs in Phase 2 or Phase 3 development Stock buyback program: Repurchased and retired 648,048 shares for an aggregate of $16.0 million Company acquisitions: Completed seven acquisitions, accumulating $11.
Peer review at the service of society
Nature Nanotechnology - The peer review system, as we know it now, is a relatively recent achievement. It will still evolve to better fit the needs of science and society in the future.
Douglas County Commissioner Mary Ann Borgeson reflects on 32 years in politics
As Women’s History Month highlights the achievements of women in society and culture, one woman has served the metro area community for more than three decades.
Orange Bank & Trust Company Celebrates Women’s Leadership at Annual Bronx Women in Business Event
MIDDLETOWN, N.Y., March 17, 2026 (GLOBE NEWSWIRE) -- Orange Bank & Trust Company proudly hosted its second annual Bronx Women in Business event recently, an initiative created to celebrate the achievements, resilience, and leadership of women throughout the Bronx business community. Founded by Vanessa Baijnauth, Branch Manager of the Bank’s Williamsbridge Road office, along with the dedicated Bronx Women in Business Committee, the event continues to serve as a dynamic platform for empowering wom
Call for Entries: Globee® Awards for Business Invite Local and Small Businesses Across the United States to Nominate Their Achievements
The Globee® Awards for Business, part of the Globee Awards' portfolio of merit-based and data-driven business recognition programs with worldwide participation, are now accepting entries and invite local and small businesses across the United States to nominate their achievements.
Partisanship and science
I recently participated in a symposium of the Denver-based Institute for Science & Policy, during which I had a “fireside chat” with Tony Mills of the American Enterprise Institute. Mills has written extensively on the politicization of science, and the two of us had a very enjoyable hour-long conversation on the topic. You can watch it below. The main questions we dealt with are why there is such a vast partisan gap in trust of science, and to what extent this is a unique moment. Mills helpfully brings a good deal of data to the discussion, as he did in this useful piece at Issues in Science & Technology. Tusk depends on reader support. To support this work, please become a paid subscriber. Subscribe Note this graph, drawing on a range of survey data to demonstrate partisan attitudes toward science since 1970s. As it demonstrates, there’s been a very sharp partisan divergence in confidence in science during the Trump Era, starting prior to the Covid pandemic. At least in part, we can attribute this to a rise in populist anti-science rhetoric embraced by Trump, his appointees, and those in his media orbit. But as the graph also shows, the partisan divide has existed in the past, and it’s not always in the same direction. The largest divergence in party views toward science prior to 2016 was in the 1970s, when liberals equated scientific achievement with the military-industrial complex and thus trusted it less. That era of scientific mistrust is often overlooked. Indeed, as Mills notes, the Moon landings (1969-72), which today are considered one of the last great moments of national unity, were experienced nothing like that at the time. There was sharp debate back then over whether the Apollo missions were worth the vast expenditures when the country had so much else to deal with. It’s outside the dataset, and we don’t have the partisanship lens for it, but the 1950s was another deeply anti-science decade, with critics of intellectuals and college professors alleging their ties to communism and their lack of commitment to basic American moral beliefs. This was the subject of Richard Hofstadter’s 1962 book Anti-Intellectualism in American Life, in which he quotes religious leaders like Franklin Graham: [In place of the Bible] we substituted reason, rationalism, mind culture, science worship, the working power of government, Freudianism, naturalism, humanism, behaviorism, positivism, materialism, and idealism. [This is the work of] so-called intellectuals. Thousands of these “intellectuals” have publicly stated that morality is relative—that there is no norm or absolute standard.… This fervor was heavily whipped up by Sen. Joe McCarthy (R-Wisconsin), although it’s clear that not all his fellow Republicans were on board with his red-baiting. What ended that era? The simple answer is the 1957 launch of Sputnik. Americans became afraid that they were losing to Soviet scientists, and suddenly university researchers and government projects were awash with funding. In our conversation, I asked Mills about the possibility of us having a Sputnik moment again that would rally the American public in favor of science today. Mills argued that the COVID-19 pandemic was essentially a Sputnik moment — a terrifying threat to all Americans that required scientific advances to address. But thanks in part to political polarization and the populist and conspiratorial leanings of Donald Trump, we got the opposite of a unifying moment. Many Americans turned against science, despite science actually stepping up in that moment. As we discussed in the chat, it’s not clear what scientists could or should be doing in this moment to increase faith in their work. As Mills notes, one of the chief complaints against scientists and professors is that they’ve become too political; scholars becoming even more political might not help them achieve their goals. This (mainly Republican-driven) anti-science era will end, of course, but it’s not clear what event will bring that about. Share
Opinion | A Centenary for Rocket Science
Robert H. Goddard achieved the first liquid-fuel launch on March 16, 1926.
Resident Evil Requiem’s scariest moment actually comes from Leon’s campaign
In a surprise twist, Resident Evil Requiem's scariest moment doesn't come from the defenselessness of Grace; it actually happens while playing as Leon.
Trump is searching for an endgame to the Iran war
Senior officials privately expressed doubt the Trump administration can achieve the overthrow of Iran's government and the destruction of its nuclear program through military means.
JA CEO Challenge: Jackson-area students pitch business ideas for prize money
High school students from Jackson and Lenawee schools competed in the final “Launch” phase of Junior Achievement’s CEO Challenge at the Jackson Area Career Center on Saturday.
Mamdani and business leaders disagree on a lot, but they seem to chat a lot, too
Several business leaders say they talk with the mayor, a democratic socialist who is trying to achieve an ambitious agenda amid signs of a slowing economy.
Xbox Ally X handhelds will soon get a performance boost
Microsoft has announced that ROG Xbox Ally X handhelds will get a performance boost in April, thanks to Automatic Super Resolution.
Three Baystate Health Hospitals Achieve 2026 Healthgrades Patient Safety Excellence Award
Baystate Health is pleased to announce that Baystate Franklin Medical Center, Baystate Noble Hospital, and Baystate Wing Hospital have achieved the 2026 Patient Safety Excellence Award™ from Healthgrades, the #1 site Americans use to find a doctor or hospital.
ASU-led SPARCS mission achieves 'first light,' marking the start of its science operations in orbit
The Star-Planet Activity Research CubeSat, or SPARCS, has captured its first images of stars from space. This milestone marks the start of its science operations in orbit.Arizona State University leads the SPARCS mission, which is funded by NASA. It is the first CubeSat mission dedicated to long-term ultraviolet monitoring of nearby low-mass stars. These stars are the most common in our galaxy and often have Earth-sized, possibly habitable planets.
Xbox to release "iconic games from the past" this year for 25th Anniversary
Xbox VP Jason Ronald revealed that the Xbox Backwards Compatibility program will get a major 2026 update with the release of some "iconic games" this year.
Trump Advisers Urge Him to Find Iran Exit Ramp, Fearing Political Backlash
The president characterized the military mission as mostly having achieved its goals, but he didn’t provide a clear timeline for ending the Iran operation.
LSA needs to scrap its natural science requirement
To meet LSA’s natural science requirement, most students select two of these courses and exert the minimum effort needed to acquire an A — which could be a problem because most feel they’re learning next to nothing. LSA’s natural science course requirement forces students to take classes they lack interest in and fails to achieve any meaningful development of natural science skills or knowledge. It should be scrapped.
In War’s First Week, a Punishing Military Campaign With No Coherent Endgame
The U.S. and Israel have pounded Iran’s leadership and undercut its defense capabilities, but President Trump has offered wildly different explanations for what he hopes to achieve.
iPhone 17e Benchmarks Reveal A19 Chip Performance With a Tiny Catch
The first benchmarks for the iPhone 17e surfaced in the Geekbench 6 database today, offering a closer look at the A19 chip's performance. For multi-core CPU performance, the highest score the iPhone 17e achieved so far is 9,241. As expected, this is nearly identical to the standard iPhone 17 model with the A19 chip, which has an average multi-core score of 9,249. There is one tiny catch, as the iPhone 17e has a 4-core GPU, whereas the iPhone 17 has a 5-core GPU.
WATCH: Leavitt clarifies what Trump's demand for Iran's 'unconditional surrender' means
Asked what Trump meant by accepting only “unconditional surrender,” White House press secretary Karoline Leavitt said Friday that will be achieved when the president “determines that Iran no longer poses a threat to the United States of America” and the mission’s goals have “been fully realized.”
Our transformation in action
Business Insider saw year-over-year growth in visits and return visits, in both January and February — a significant achievement in today's landscape.
Adial Pharmaceuticals Reports 2025 Fiscal Year Financial Results and Provides Business Update
GLEN ALLEN, Va., March 06, 2026 (GLOBE NEWSWIRE) -- Adial Pharmaceuticals, Inc. (NASDAQ: ADIL) (“Adial” or the “Company”), a clinical-stage biopharmaceutical company focused on developing therapies for the treatment and prevention of addiction and related disorders, today provided a business update and reported its financial results for the 2025 fiscal year ended December 31, 2025. Key Highlights: Regulatory Progress: Achieved positive clinical study results from the AD04-103 pharmacokinetics (P
The Galaxy S26 Ultra leads Samsung's new flagship family to its first big sales achievement
Despite rising prices, the Galaxy S26 lineup has so far managed to outsell the S25 trio in South Korea.
Apple's M5 Max Chip Achieves a New Record in First Benchmark Result
The first Geekbench 6 result for a 16-inch MacBook Pro with the M5 Max chip surfaced today, and Apple has achieved record-breaking performance. In this unconfirmed result, the M5 Max with an 18-core CPU achieved a score of 29,233 for multi-core CPU performance, which tops the 27,726 score achieved by the Mac Studio's M3 Ultra chip with a 32-core CPU. M5 Max is now the fastest Apple silicon chip ever, and it even topped every other consumer PC processor in the Geekbench database.
Free Play Days has four free Xbox games to play this weekend
With the weekend now on the horizon, Free Play Days has returned with four games that Xbox Game Pass subscribers can play for free over the next several days.
Two Mizzou professors recognized by the Academy of Science of St. Louis
March 3, 2026 Two University of Missouri professor were recently recognized for outstanding achievements by […]
WHO EPI-WIN webinar: Women in Health Emergencies
This webinar is held in alignment with the International Women’s Day commemoration on 8 March. It celebrates the tremendous contributions of women and girls in shaping a more equitable future, while also shining a light on the persistent challenges that must be overcome to achieve meaningful gender equality in emergency settings.
Trump’s Iran war message marked by exaggerated threats and shifting, contradictory goals
In the weeks leading up to President Donald Trump’s decision to strike Iran and in the frenetic days since, the president and his administration have offered several evolving explanations — at times exaggerated or at odds with US intelligence — to justify why the attacks were necessary and what the US ultimately hopes to achieve.
Regional development goals can improve global health in an era of diminished multilateralism
Nature Health - With almost all of the Sustainable Development Goals not being achieved amid declining global solidarity, countries would be better served by regional development goals.
Manternach receives Early Extension Award
Jacob Manternach, industry extension specialist in animal science, is the recipient of the staff 2026 Early Achievement in Extension and Outreach Award from the College of Agriculture and Life Sciences at Iowa State University. For the past two-and-a-half years, he has played a pivotal role in the success of the meat science extension program.
Xbox gets over 35 new games next week
A whopping 36 new games, including Marathon, Planet of Lana II, and Legacy of Kain: Defiance Remastered, launch for Xbox next week.
Wenatchee entrepreneur turns junk removal into growing NCW business
Springtime often inspires people to clean out garages and sheds and restore their homes’ environments. Hauling unwanted items, or “junk,” is one way to achieve that.
Schoolcraft women's basketball achieves perfection with 28-0 regular season
Schoolcraft College women's basketball team made history with a perfect 28-0 regular season; now the Ocelots are aiming for a national title.
Schoolcraft women's basketball achieves perfection with 28-0 regular season
Schoolcraft College women's basketball team made history with a perfect 28-0 regular season; now the Ocelots are aiming for a national title.
Greater Houston Black Chamber of Commerce working with local businesses to achieve long-term success
Over its 91-year history, the Greater Houston Black Chamber of Commerce has supported the growth, development, and sustainability of local businesses.
Scientists lay out what we do and don’t yet know about moths and butterflies
Key points Scientists have published a broad review of what they’ve learned about moths and butterflies over the last few decades. Special attention is given to pivotal moments during the ~300 million-year history of the group. These include changes in diet that moths achieved, in part, by p
Trump's post-State of the Union sales job begins now
His address Tuesday was a declaration of pride in the achievements of his still-young second term, as he boasted of an economic renaissance at home while he's imposed a new world order abroad. Trump is getting his first opportunity to test drive that midterm year message later this week.
Whitmer's State of the State: Goals met, visions unachieved
Gov. Gretchen Whitmer outlined a broad array of policy goals in her State of the State speeches over the years. How many materialized?
Strib Varsity Athletes of the Week: Meet seven high achievers
Maya Kilian, Nathan Carr, Lauren Hansen, Peyton Hoffman, Jo Jo Mitchell, Bryce Paumen, Pierce Rohman were honored for their performances this week.
How does politics influence interpretive signs at National Park Service sites?
The Trump administration recently ordered the National Park Service to remove interpretive signs that discuss slavery at Independence National Historical Park in Philadelphia, following an executive order issued last year stating that public monuments should not “inappropriately disparage Americans” and instead “focus on the greatness of the achievements and progress of the American people.” A […]