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DanDan restaurant in Milwaukee's Third Ward is temporarily closed
According to a sign posted on the door of the popular Third Ward American-Chinese restaurant, DanDan has been closed since March 20.
DanDan restaurant in Milwaukee temporarily closed by health department
Popular Third Ward restaurant shuts down pending health department re-inspection; reason for closure not yet released.
Latest World & National News & Headlines
USA TODAY delivers current national and local news, sports, entertainment, finance, technology, and more through award-winning journalism, photos, and videos.
Building a Culture of Health: BJACH Opens Armed Forces Wellness Center at Fort Polk
FORT POLK, La. — Bayne-Jones Army Community Hospital marked a significant step forward in supporting warfighter readiness and community well-being with the grand opening of its new Armed Forces Wellness Center on March 23. The center, located on the first floor inside BJACH, provides Soldiers, Families, civilian employees and beneficiaries with access to personalized health assessments, education and coaching designed to improve overall health and performance.
Inaugural Health Care by Food research award honors excellence in food is medicine science
DALLAS, March 23, 2026 — At a time when American dietary patterns are facing renewed attention, the American Heart Association has announced its inaugural Health Care by Food™ Most Impactful Food Is Medicine Research Award, honoring the year’s most...
Inaugural Health Care by Food research award honors excellence in food is medicine science
DALLAS, March 23, 2026 — At a time when American dietary patterns are facing renewed attention, the American Heart Association has announced its inaugural Health Care by Food™ Most Impactful Food Is Medicine Research Award, honoring the year’s most...
Trump orders War Dept to postpone strikes on Iranian energy sites, citing 'productive' talks to end war
President Donald Trump, in an all-caps post early Monday morning, declared progress toward "resolution" of the war on Iran.
Meet CT’s 2026 Women in Business honorees
Hartford Business Journal’s 2026 Women in Business awards recognize top leaders who are making a significant difference within their organization and the broader community.
An end to the battle between touchscreens and long fingernails is on the horizon
Anybody who has tried to use a smartphone or tablet with long nails knows that there's a learning curve. Rather than effortlessly tapping with a fingertip, you must awkwardly lay the pads of your fingers ...
As mayoral election looms, D.C.’s business class worries about what’s next
A potential leftward shift in the wake of the pandemic and the Trump administration’s cutting of thousands of federal jobs has sparked unease in the city’s business community.
Personnel note: Tampa Electric names Ed Narain as Director of Regional Affairs
'Tampa Electric has a long history of supporting the growth and success of the communities it serves, and I look forward to helping strengthen those partnerships.'
The politics of disability at the Academy Awards
Throughout history, disabled bodies have been portrayed as a burden.
Breaking the Cycle review – meet the charismatic Thai politician striving to change his country’s history
Gripping documentary examines the Future Forward Party’s unprecedented 2019 election result, and its leader’s aim to break Thailand’s repeated military coups
BUSINESS MONDAY: Spotlight on Sarah's Cheesecakes & Cafe in Pittsfield
The small family-owned and -operated operation is celebrating its 20th anniversary—and looking forward to many more years to come.
Jerry Hanlon, longtime Michigan football coach, dies at 96
"Michigan Athletics has lost one of the finest ambassadors and mentors our football program has ever known," U-M AD Warde Manuel said in a statement.
Lessons from Binghamton led alumni award winner to public health
Clare Biging ’16 is an epidemiologist and public health advocate at the New York City Department of Health and Mental Hygiene.
Linux 7.0-rc5 Released: Linux 7.0 "Starting To Calm Down"
Linus Torvalds just issued Linux 7.0-rc5 as we inch toward the stable Linux 7.0 kernel release in April.
Former 'Bachelorette' star James Taylor re-arrested on assault charges in Texas
Former 'Bachelorette' star James Taylor has been re-arrested in Texas in connection to his 2024 assault case.
Educational Service Center awarded Teach Computer Science 2.0 Grant
The Educational Service Center of the Western Reserve has been awarded $584,614 through the Ohio Teach Computer Science 2.0 State Grant, a competitive initiative funded by the Ohio Department of Higher Education. As part of an $8 million…
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Introducing the 2026 Northeast Arkansas Outstanding Business Awards finalists - Talk Business & Politics
For several weeks, we have been soliciting the region’s business community for nominations for our first recognition program of the year: the Northeast Arkansas Outstanding Business Awards, presented by Arvest...
Oscar-Winning Alumnus Returns to Pasadena’s ArtCenter for Entertainment Design Expo
One week after winning the Academy Award for Best Animated Feature, KPop Demon Hunters co-director Chris Appelhans returns today to ArtCenter College of Design, the Pasadena campus where he studied illustration, for the college’s third annual Entertainment Design Expo. The expo, known as ENTX, opens the Hillside Campus to the public for a full day of gallery exhibitions, game playtesting, animation screenings and interactive experiences featuring work from more than 200 ArtCenter students and alumni. General admission is free with advance registration. Two industry panels — including Appelhans’s talk — require $15 tickets. Appelhans, who graduated from ArtCenter with a bachelor of fine arts in 2002, co-directed KPop Demon Hunters with Maggie Kang. The animated film, produced by Sony Pictures Animation and released on Netflix, became the streaming platform’s most-watched film in history, according to Netflix, and swept awards season with wins at the Golden Globes, the Annie Awards and the Grammys before taking the Oscar on March 15. His talk and audience Q&A is scheduled from noon to 1 p.m. in the Ahmanson Auditorium. Doors open at 11:30 a.m. The film’s ArtCenter ties extend beyond its co-director. Art director Angela Sung, cinematographer Gary H. Lee, visual development artist Celine Kim and painter Simon Baek are all ArtCenter graduates who worked on the production, according to the college. The free portions of ENTX include a concept design showcase, a production design gallery, a model gallery, a stop motion studio preview, an alumni gallery and a KPop Demon Hunters fan art gallery. Visitors can also playtest games designed by ArtCenter students. An Animation Shorts Showcase runs from 2 to 3 p.m. and includes “Boy, I’m Scared,” a capstone short by ArtCenter graduate Lindsey Tenaglia that was named a semifinalist for the 2025 Student Academy Awards in the animation category. Also screening
Scientists Startled by What Happens When They Point Hubble at Comet
An extraordinary coincidence occurred when astronomers pointed the Hubble Space Telescope at a wayward comet.
Former, current NBA players sound off on NBA expansion as vote looms
The NBA is moving closer towards expanding to Las Vegas and Seattle. Here's what players think about the move.
Get ready to vote in the next Detroit Community Choice Awards
The awards program seeks to shine a light on outstanding businesses in Wayne, Oakland and Macomb counties.
Are AI tokens the new signing bonus or just a cost of doing business?
Maybe tokens really will become the fourth pillar of engineering compensation. But engineers might want to hold the line before embracing this as a straightforward win.
Marc Abrahams, founder of the satirical Ig Nobel Prizes: ‘Scientists in the US are very angry. People are waking up’
The awards are moving to Switzerland, because their founder believes he can no longer guarantee the laureates’ safety in the United States
Madison Black Chamber of Commerce prepares 8th business awards recognition program
The Madison Black Chamber of Commerce is hosting its 8th Black Business Awards Recognition and Exhibition Program on Thursday.
Four-star forward Joe Philon commits to UCLA
Joe Philon, a four-star power forward in the 2026 class, has committed to UCLA, he told On3. The 6-foot-8 senior out of Montverde Academy (FL) chose the Bruins after considering Ohio State, South Florida, UNLV, and Xavier. Philon, a native of Tampa, Florida, is the No. 56 overall player in the 2026 class, according to […]
G.O.P. Bid to Target Transgender Athletes Falls Flat in the Senate
In moving to bar transgender women and girls from women’s and girls’ sports, Republicans sought to put Democrats in an awkward political spot on a sensitive issue ahead of the midterm elections.
Top 5 states with the highest number of safest hospitals, according to new report
Healthgrades named 438 hospitals across 40 states for its 2026 Patient Safety Excellence Award, with Texas and Florida among the top-performing states.
City of Santa Barbara Seeks Nominations for 2026 Business in Art Award
Nominations are now open for the 2026 City of Santa Barbara Business in Art Award, for local businesses that support artists
16 award-winning photographs from around the world
The Sony World Photography Awards announced the winning and shortlisted photographers of the 2026 National and Regional Awards .
Wisconsin's Caroline Harvey wins Kazmaier Award as top player
Wisconsin defender Caroline Harvey voted as the winner of the Patty Kazaier Memorial Award for college women's hockey's top player.
A massive freshwater reservoir is hiding under the Great Salt Lake
A hidden freshwater system deep beneath the Great Salt Lake has been revealed using airborne electromagnetic surveys. Scientists found that freshwater extends much farther under the lake than expected, reaching depths of up to 4 kilometers. The discovery began with mysterious reed-covered mounds formed by pressurized groundwater pushing upward. Researchers are now investigating whether this underground water could help control hazardous dust from the drying lakebed.
Community's Choice Awards spotlight: Oliv Epicurean Grill
Local favorites don’t nominate themselves. Volusia-Flagler Community’s Choice Awards nominations are in the final days.
Community's Choice Awards spotlight: Rockledge Gardens
The Brevard Community’s Choice Awards are picking up steam. Have you nominated your local favorites yet?
Community's Choice Awards spotlight: Cool R Us
Momentum is building for the Best of Bold City Community’s Choice Awards. Nominate before you forget.
Community's Choice Awards spotlight: Affiliated Dermatologists
Milwaukee Top Choice Community’s Choice Awards nominations are almost done. Don’t ghost your favorite local businesses.
Combating youth suicide tilts increasingly toward early intervention
A suicidal child or teenager may never talk of taking their life. Parents, peers and teachers might not even know they’re living with mental illness. Despite younger generations showing greater openness to discussing mental health struggles, fears of punishment or social exclusion remain, experts say. Even at medical appointments, minors
Nebraska lands the commitment of 3-star athlete Kaden Howard
The feel-good momentum surrounding the Nebraska athletic department continues to build following the men’s basketball team’s first-round NCAA Tournament victory—and it’s now carrying over onto the recruiting trail. The Cornhuskers have secured a commitment from 3-star athlete Kaden Howard, a 5-foot-10, 160-pound playmaker out of Miami, Florida. Howard picked Nebraska over Louisville, West Virginia and […]
Laid Off in Midlife, China’s Reform Generation Braces for Downward Mobility
The future once seemed boundless for those who grew up during China’s reform era. Now in middle age, they are pinned between economic stagnation and institutional age discrimination.
The mental health effects of gun violence near schools
Dr. Scott Hadland from Mass. General Brigham discusses new data that shows the amount of shootings near schools is trending downwards.
Pacers' Eddie White named to Hall-of-Fame in hometown
Pacers public relations director and post-game radio host Eddie White was named to the Luzerne County Chapter of the Pennsylvania Sports Hall of Fame.
Baughman earns Southern Weed Science Society outstanding educator award
Todd Baughman, Ph.D., has, received the Southern Weed Science Society Outstanding Educator Award recognizing a range of education activities.
Why Tencent Music Entertainment Plunged Almost 30% This Week
The Chinese music streaming leader posted decelerating subscription revenue and said it would no longer disclose certain metrics going forward.
Building scientists in Charlottesville: Inside the UVA Innovation Hub
The award-winning partnership between the city schools and UVA’s School of Education expands learning into the community.
Mark Cerny Confirms Frame Generation "Should Be Seen At Some Point On PlayStation Platforms"
"I look forward to discussing this more in the future!"
New controls can stretch, blur and even reverse quantum time flow
In new research published in Physical Review X, scientists have designed quantum control protocols that generate processes more consistent with time flowing backward than forward. The protocols—techniques ...
US House Democrat blasts Commerce's 'highly concerning' $1.6 billion USA Rare Earth deal
A senior House Democrat accused U.S. Commerce Secretary Howard Lutnick on Thursday of structuring Washington's $1.58 billion investment into USA Rare Earth in a way that gives the government "highly concerning" leverage over the company while boosting Lutnick's family-run investment firm.
Letai: “From this point forward, it really is much more like business as usual at the NCI.”
NCI Director Anthony Letai appeared before the National Cancer Advisory Board Committee March 17 to maneuver through thorny topics while reiterating his message of reassurance: Stability. Stability. Stability. NCI is sturdy and will weather the storms. “The mission hasn’t changed at the National Cancer Institute,” Letai said in his remarks to the committee. “The resources […]
Jefferson Health hit with $108 million verdict in Einstein birth injury case
The verdict is the biggest medical malpractice verdict in the city since a record-setting $183 million award against Penn Medicine three yeas ago in another birth-injury case.
Sports writer and photographer win Quill awards for work for Guardian Australia
Jonathan Horn scooped best sports feature prize for a series on AFL, while Chris Hopkins won for pictures of a cancer sufferer caring for her son
Towards responsible AI for mental health and well-being: experts chart a way forward
On 29 January 2026, WHO‑supported experts met at a TU Delft workshop to address the rapid, largely untested use of generative AI for mental health support. Participants warned of risks to well‑being, especially for young people, and called for stronger governance.
Santa Fe small businesses awarded microgrants to pursue new opportunities
A total of 40 Santa Fe business owners received the microgrants, which were valued at between $3,000 and $5,000.
Ayo Dosunmu bringing 'genuine energy' as Wolves take on Blazers
Nobody can fill Anthony Edwards' shoes, but Ayo Dosunmu is doing his best to help.
14 silly, never-before-seen images from the Comedy Wildlife Photography Awards
Nature, you're hilarious.
Scientists turn CO2 into fuel using breakthrough single-atom catalyst
Researchers have created a cutting-edge catalyst that turns CO2 into methanol more efficiently than ever before. Instead of using clumps of metal atoms, they engineered a system where each single indium atom actively drives the reaction. This dramatically reduces energy needs while making the process easier to study and optimize. The result could accelerate the shift toward cleaner fuels and sustainable chemical production.
Super early 2027 Oscars predictions: Will Amy Adams finally win her first Academy Award?
Early 2027 Oscars contenders are already in the running for top awards. Here are EW's super early predictions for nominees, from Tom Cruise and Amy Adams to 'The Odyssey' and 'Dune: Part 3.'
Justin Bieber and Usher had "heated exchange" at Beyoncé, Jay-Z's Oscars after-party (Report)
The longtime friends and collaborators got into a "heated exchange" following the Academy Awards, TMZ reports.
City of Santa Barbara Seeks Nominations for 2026 Business in Art Award
Credit: CourtesyCredit: Courtesy (SANTA BARBARA, Calif.) – Nominations are now open for the 2026 City of Santa Barbara Business in Art Award, which
New dispute emerges around Subnautica 2’s early access release
Lawyers for the ousted—and now partially reinstated—leadership team of Unknown Worlds, the studio behind Subnautica 2, are crying foul over news that the game will be released into early access in May. The release announcement earlier this week was made improperly, potentially “damaging the game and sowing additional confusion among the Subnautica community,” the lawyers said in a letter sent on Tuesday to Vice Chancellor Lori Will of Delaware’s Court of Chancery. In their letter, the lawyers also floated the idea of asking Will to find Krafton in contempt of the court’s ruling. The letter was sent just one day after Will’s bombshell ruling that publisher Krafton had breached its contract with Unknown Worlds’ executive team, when it fired them last June. The new issue isn’t necessarily the May early access timeframe, but how the news was announced. The letter and Krafton’s response have not been previously reported. A quick recap of prior events: Subnautica 2 is an unreleased, underwater survival adventure and the most-wishlisted game on Steam. Last year, longtime Unknown Worlds CEO Ted Gill, along with studio co-founders Charlie Cleveland and Max McGuire, were fired by Krafton. They swiftly sued, saying the publisher had terminated them to avoid paying out up to $250 million in potential performance-based bonuses. The studio leaders had hoped to earn that with an early access release of the game, which Krafton had blocked. The publisher argued in court that Subnautica 2 wasn’t ready, which the ousted execs disputed. On Monday, Will ruled that Krafton had violated its contract, firing the execs to avoid the performance payouts, and that it had to reinstate Gill and give him full authority over any early access release for Subnautica 2. On Tuesday, IGN reported on a new memo issued that day to Unknown Worlds staff by Steve Papoutsis, the executive Krafton had put in charge of Unknown Worlds after the 2025 firings. In the note, Papoutsis said that Subnautica 2 had passed a key development milestone “last week” and that he and Krafton had determined the game “is ready for Early Access release in May.” This news appeared to catch the lawyers for Gill, Cleveland and McGuire by surprise. On Tuesday night, they sent a letter to Will expressing “serious concerns” about whether it would be possible to forge an agreement with Krafton consistent with the judge’s order. Papoutsis’ memo was a problem, they wrote. He didn’t have the authority to declare anything about Subnautica 2’s release. As of 9am ET on Monday, March 16, the effective date of Will’s order, Papoutsis wasn’t CEO of Unknown Worlds. Gill was. And, per Will’s order, only Gill could make Subnautica 2 release decisions. They continued: Krafton self-servingly announced the launch without any regard to its impact on the game, the team, or the community—let alone this Court’s Opinion. Announcing the release of a game is momentous, and it is typically accompanied by significant marketing activity, fanfare, and community coordination. And most importantly, the announcement is carefully designed to maximize excitement for the game. That entire process was supposed to be driven by Mr. Gill. However, in defiance of the Court’s Opinion, Krafton has now taken that away, further damaging the game and sowing additional confusion among the Subnautica community. The lawyers speculated that Krafton had “intentionally leaked” Papoutsis’ memo and then issued an official statement to confirm the leak. Game File is a reader-supported publication. My reporting is only possible through support from readers like you. To support my work, consider becoming a free or paid subscriber. Subscribe On Wednesday, lawyers for Krafton defended their client in their own letter to vice chancellor Will, saying nothing they did violated her order nor showed contempt: Papoutsis’s message was simply celebrating the UW employees’ efforts toward a past event: Krafton’s pre-Opinion determination that Subnautica 2 was ready for Early Access release. There was nothing improper about conveying the results of the milestone review or thanking the development team for their dedication and talent. They added that Gill could still make his own call about Subnautica 2’s release: In his role as CEO, Gill will be able to assess independently his views on the state of Subnautica 2 and the appropriate release schedule; nothing in Papoutsis’s message alters Gill’s authority or discretion. Vice chancellor Will has not responded to the letters and doesn’t necessarily have to. Both parties were previously ordered by Will to confer this week and submit a proposed judgment consistent with her ruling. The letter from Gill’s attorney’s this week doesn’t indicate whether he would or would not support a May release for Subnautica 2. But it could limit his options. And, if Gill’s lawyers are right, the lack of marketing fanfare around the leak of the May date could dull the launch of the game. Any harm to Subnautica 2’s launch is an extra sensitive issue given the context of the legal dispute: millions of dollars of payouts are on the line, tethered to the scale of the game’s initial performance. In her ruling on Monday, Will noted that there was obvious “bad blood” between Gill’s side and Krafton but that the two would need to work together: “They can—and must—act in good faith to navigate their remaining contractual relationship.” Item 2: A new kind of couch co-op game A highlight of GDC each year is the Alt.Ctrl showcase that features games played with extremely experimental controllers. Perusing this year’s offerings last Friday, I found a game controlled with giant scissors, another with big toothbrushes and one that amounted to dumpster diving. My favorite was Pivot, a co-op game about collectively maneuvering a couch. It was developed by students at the University of Utah’s masters of arts and engineering games program. Players lift and tilt the physical couch in order to control the position of a virtual one. That virtual one is moving through an obstacle course on-screen, while being pursued by a giant skull. Developer Nishant Verma told me at GDC that the couch is made of styrofoam (this became more evident as I watched!) and that the name was a riff on an episode of the sitcom Friends. Item 3: In brief… 🚫 Ubisoft is laying off more than 100 workers at its Red Storm studio, as the North Carolina location known for decades for its Tom Clancy games, ceases in-house game development, VGC reports. 👀 On Monday, Nvidia’s revealed its DLSS 5 AI-driven graphics technology that purports to improve game graphics… and it has been roasted about it by the media and the online gaming public for the remainder of the week. The tech changed the faces of characters in footage from Resident Evil Requiem, Hogwarts Legacy and EA Sports FC, drawing accusations of giving carefully art-directed games the generic look of AI “slop.” Nvidia CEO Jensen Huang had said on Monday that “DLSS 5 is the GPT moment for graphics—blending handcrafted rendering with generative AI to deliver a dramatic leap in visual realism while preserving the control artists need for creative expression.” By mid-week, Huang was telling Tom’s Hardware that the new tech’s critics were “completely wrong” because game-makers could still “fine-tune the generative AI” to suit their game’s aesthetics.
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Forum on harnessing Artificial Intelligence for health equity
Register to this forumOver the past decade, artificial intelligence (AI) has significantly evolved in complexity, performance, and utility. Its integration across a wide range of industrial sectors has accelerated, with healthcare emerging as one of the most transformative sectors. In this sector, AI has enabled high-impact applications – from enhancing the speed and accuracy of disease diagnosis and supporting clinical decision-making, to strengthening public health initiatives such as disease surveillance and workforce optimization. Moreover, AI holds immense potential to empower individuals, enabling them to take greater control of their personal health and well-being. Yet the central question remains: Who benefits, who is at risk, and do these innovations close or widen health inequities? While the potential of AI-enabled applications is substantial, many countries have approached their adoption with caution. This hesitancy stems from concerns about risks and benefits, including model bias, data breaches, privacy violations, and the erosion of professional skills due to over-reliance on AI. Additional barriers include inadequate data infrastructure and a lack of robust evidence on the most effective forms and interfaces of AI to enhance service delivery and system performance. Moreover, the rapid rise of Generative AI has introduced a heightened urgency for the development of comprehensive governance and ethical frameworks. The Asian Development Bank (ADB) Health Practice Team and Digital Sector, in collaboration with the World Health Organization (WHO) Regional Office for the Western Pacific, are convening the Forum on Harnessing AI for Health Equity on 25–26 March at ADB Headquarters. Senior health officials from 16 developing member countries (DMCs), alongside leading researchers, innovators, and policymakers from across Asia and the Pacific, will engage in discussions on how AI can be governed, financed, and scaled to deliver healthier lives for all. The forum is funded through the High-Level Technology Fund with support from the Government of Japan. Objectives The two-day forum aims to:Identify high-impact, evidence-based health AI use cases suitable for resource-constrained settings and map out a pipeline for potential supportIntroduce and validate the WHO's policy guidance on minimum necessary ecosystem for countries and institutions to self-assess readiness for AI adoptionObtain initial commitment from participating stakeholders to join a pilot regional initiative focused on data/model sharing for a priority health challengeEndorse a prioritized set of actionable policy recommendations focusing on governance, regulation, and sustainable financing necessary to scale high-impact health AI use cases in resource-constrained settings Target participants The forum will convene participants from 16 ADB DMCs including Bangladesh, Bhutan, Cambodia, Cook Islands, Fiji, Indonesia, Lao People's Democratic Republic, Mongolia, Nepal, Palau, Papua New Guinea, Philippines, Sri Lanka, Thailand, Uzbekistan, and Viet Nam. In addition, health system leaders and practitioners, private sector technologists, academic experts, representatives from civil society organizations, development partners, and philanthropic institutions engaged in AI for Health from Australia, the People’s Republic of China, Japan, Malaysia, New Zealand, Singapore, and the Republic of Korea will also be invited. SessionsDay 1 (25 March)Session 1: AI Use Cases for the Care Continuum: Improving Access and QualitySession 2: Adopting a risk-based approach for AI use case prioritizationSession 3: Establishing the Minimum Ecosystem for Implementation Risk ManagementSession 4: Future-Ready Health Workforce: Building Competency for Human-AI CollaborationDay 2 (26 March)Session 5: The Political Economy of AI in Health: Understanding Stakeholder Interests and their Impact on EquitySession 6: AI and Health Financing: Supporting Fair Coverage and ProtectionSession 7: AI Regulation and Oversight: Pathways for Different RealitiesSession 8: The Way Forward – Building Alliances and Regional Partnership How to registerThe forum will be held in a hybrid format. In-person attendance is by invitation only, while livestreaming of the forum will be available to the public. To register, please complete this form on or before 24 March 2026.Event organizers / partnersAsian Development Bank (ADB)WHO Regional Office for the Western Pacific High-Level Technology Fund (HLTF)ContactAkihito WatabeHealth Specialist, SD3-HSDawatabe@adb.org Jae Kyoun KimHealth Specialist, SD3-HSDjkkim@adb.org
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Foxboro approves World Cup entertainment license - Boston News, Weather, Sports
FOXBORO, MASS. (WHDH) - Foxboro town leaders voted unanimously Tuesday to approve the entertainment license needed for the FIFA World Cup games to move forwardRead More
Texas vs. NC State live updates: March Madness First Four begins in Dayton; UMBC falls to Howard
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