SCROLL NEWS / DISCOVERY

Search headlines

Find the stories shaping the conversation.

Search mode
Refine results
Active filters Keyword All time

Results for " tran " 7,993 found 🔀 AI-powered Shuffle

C21 launches D2C Entertainment Summit with Audience First focus as entertainment business transforms

C21Media has launched the D2C Entertainment Summit, which will run as a track within Content London, Content Americas and Content Europe and as a standalone one-day event in London during June 2027.

c21media.net logo
Oct 7 • 8:00 AM EDT • Entertainment • c21media.net
Is your AI delivering true business growth?

RSM explores why 97% AI satisfaction masks a transformation gap in the middle market. Learn more.

rsmus.com logo
Oct 7 • 8:00 AM EDT • Business • rsmus.com
At $1,279, Google’s Xreal Aura will go head-to-head with Meta’s VR Glasses

The first transparent Android XR glasses are “weeks” away — if you made a reservation.

theverge.com logo
Oct 7 • 8:00 AM EDT • Technology • theverge.com
Hard Rock Stadium Selects Clover Sport to Power Point-of-Sale Solutions

Integrated Technology Supports Faster Transactions and Streamlined Operations Across Sports, Concerts and Global Events MILWAUKEE, Oct. 07, 2026 (GLOBE NEWSWIRE) -- Fiserv, Inc. (NASDAQ: FISV), a leading global provider of payments and financial services technology, today announced that Hard Rock

investors.fiserv.com logo
Oct 7 • 8:00 AM EDT • Sports • investors.fiserv.com
Talarico camp says he opposes trans athletes if unsafe or unfair but accuses politicians of bullying students

James Talarico says he opposes transgender athletes in women's sports when safety is at risk, but his campaign won't say if he'd back a federal ban.

foxnews.com logo
Oct 7 • 7:32 AM EDT • Politics • foxnews.com
Who Controls the Technology Protecting Your Business?

Cybersecurity sovereignty gives organizations transparency, hybrid control, and resilience over critical systems, writes Claudio Martinelli.

mexicobusiness.news logo
Oct 7 • 7:30 AM EDT • Business • mexicobusiness.news
India's 2036 Games bid fuels sporting superpower dreams but hurdles, heavyweight rivals remain

India's bid for the 2036 Olympics sits at the heart of a wider effort to transform the country into a sporting superpower and the Indian Olympic Association is convinced it can come out on top in a fiercely competitive process, its chief executive officer Raghuram Iyer told Reuters on Wednesday.

reuters.com logo
Oct 7 • 6:25 AM EDT • Sports • reuters.com
$4.6 Million Construction Permit Issued for Upcoming 49,000 SF Round1 Entertainment Venue

Round1 Bowling & Arcade has received a permit valued at $4.6 million to build its upcoming location at Westfield Wheaton. The nearly 49,000 SF entertainment venue will transform the former […]

mocoshow.com logo
Oct 7 • 6:00 AM EDT • Entertainment • mocoshow.com
Delaware details still slim as Penn Medicine plans new surgery centers

Penn Medicine unveiled a new plan to bring 18 ambulatory surgical centers to the region. Details remain slim on what's coming to Delaware.

delawareonline.com logo
Oct 7 • 5:44 AM EDT • Health • delawareonline.com
Sony Sells off Dozens of XR Patents to Meta in Apparent Pullback from AR/VR Hardware

Meta has acquired a number of Sony patents, including some related to XR headsets, suggesting Sony is significantly pulling back from its XR ambitions. The News As first reported by ZDNet Korea, a recorded transfer of 43 U.S. patent properties took place between June and September 2026, which include virtual, augmented and mixed reality headset […]

roadtovr.com logo
Oct 7 • 4:53 AM EDT • Technology • roadtovr.com
Chelsea backroom shake-up as transfer chief set to leave

Laurence Stewart will depart after four years with the club, with his duties already dished out

sports.yahoo.com logo
Oct 7 • 4:28 AM EDT • Sports • sports.yahoo.com
Kobel reflects on Newcastle interest and his Borussia Dortmund future

Borussia Dortmund goalkeeper Gregor Kobel has consistently been linked with a transfer over the past few years.Last summer, Newcastle United were reportedly interested in the Swiss shot-stopper, but h...

sports.yahoo.com logo
Oct 7 • 3:28 AM EDT • Sports • sports.yahoo.com
South Korea unveils $747 billion energy transition plan through 2035

South Korea's government on Wednesday unveiled a 1,000 trillion won ($747 billion) energy transition and decarbonisation strategy through 2035, aiming to expand renewable power, transform heavy industry and create new drivers of growth.

reuters.com logo
Oct 7 • 3:13 AM EDT • Business • reuters.com
BBVA to Co-Chair Climate Finance and Investments Working Group at COP31 Business Forum

BBVA will lead the Climate Finance and Investments area at COP31 to accelerate funding for the global energy transition.

bbva.com logo
Oct 7 • 2:25 AM EDT • Business • bbva.com
Pilot Project Aids Cancer Survivors in Achieving Healthy Weight and Reducing Recurrent Risk

New program will help patients improve fitness and manage weight after cancer treatment

consultqd.clevelandclinic.org logo
Oct 7 • 12:01 AM EDT • Health • consultqd.clevelandclinic.org
Redoing Daubert: Are judges letting bad science back into the court room?

Daubert was meant to keep unreliable science out of the courtroom by making judges gatekeepers who ensure the reliability and relevance of expert testimony and the underlying research. A recent Second Circuit decision raises a harder question: how deeply may a judge examine the science when evaluating an expert’s methodology before determining the scientific dispute itself? The answer could reshape how courts translate epidemiological evidence into legal proof.

acsh.org logo
Oct 7 • 12:00 AM EDT • Science • acsh.org
‘Hotel Transylvania’ Halloween party headed to Waynesville

This year, the Waynesville Parks & Recreation is throwing it’s biggest Halloween celebration yet. The Hotel Transylvania Halloween Party will be held from 5-8 p.m. Friday, Oct. 16, at the

themountaineer.com logo
Oct 7 • 12:00 AM EDT • Entertainment • themountaineer.com
Candidates share their stance on healthcare at Health Improvement Alliance forum

The Health Improvement Alliance of Saint Joseph County held an open forum on Tuesday for political candidates to share their thoughts and stances on healthcare

wsbt.com logo
Oct 6 • 10:37 PM EDT • Health • wsbt.com
“Glee” star Chris Colfer says he was ‘uncomfortable’ with the public wanting him to date Darren Criss

The actor also reflected on the strangeness of having fan fiction written about his real life: “It was really jarring and sometimes really sexual.”

yahoo.com logo
Oct 6 • 9:15 PM EDT • Entertainment • yahoo.com
Former SC GOP Gov. breaks ranks to condemn Trump’s ‘destructive’ anti-Trans slur
cnn.com logo
Oct 6 • 7:53 PM EDT • Politics • cnn.com
Atrium Health’s AirCare program reflects on four decades of patient transport

Atrium Health’s AirCare program marks four decades of patient transport, with reflections from an original flight nurse and the current director.

wxii12.com logo
Oct 6 • 6:49 PM EDT • Health • wxii12.com
😐 Neutral (22%)
love
63%
wow
37%
Top Dems push WH for transparency on election security
cnn.com logo
Oct 6 • 5:59 PM EDT • Politics • cnn.com
Google sounds really excited about 'massive' feature update hitting Pixel Buds right now

From dynamic ANC, to tap-to-mute for your microphone, to even new Live Translate capabilities, this sounds like one major update!

androidauthority.com logo
Oct 6 • 5:55 PM EDT • Technology • androidauthority.com
Three sheriff’s offices sign up for jail mental health hold reimbursements under new Wyoming law

by Maya Shimizu Harris, WyoFile Three sheriff’s offices will be the first under a new law to receive reimbursements from the Wyoming Department of Health

capcity.news logo
Oct 6 • 5:45 PM EDT • Health • capcity.news
Three sheriff’s offices sign up for jail mental health hold reimbursements under new Wyoming law

by Maya Shimizu Harris, WyoFile Three sheriff’s offices will be the first under a new law to receive reimbursements from the Wyoming Department of Health

oilcity.news logo
Oct 6 • 5:45 PM EDT • Health • oilcity.news
Health Brief: Medical devices join Trump’s tariff bargain

Plus: Trump administration turns up the heat on price transparency enforcement

washingtonpost.com logo
Oct 6 • 5:30 PM EDT • Health • washingtonpost.com
County business halts as staff experience tech issues

Due to technical issues with phone systems and servers, Jefferson County is temporarily unable to process transactions.

myleaderpaper.com logo
Oct 6 • 5:30 PM EDT • Business • myleaderpaper.com
Earth is in the firing line of a strange new type of cosmic object: a 'microblazar'

Astronomers may have discovered the first known microblazar, a long-theorized object firing a powerful beam of particles directly at Earth.

livescience.com logo
Oct 6 • 4:41 PM EDT • Science • livescience.com
Deep dive
😐 Neutral (10%)
wow
52%
ahah
48%
Milton business fined for oil spill into Lamoille River

ANR says petroleum product from Rowley Fuels Inc. overflowed from a fuel delivery truck during a transfer at their storage facility in 2024.

wcax.com logo
Oct 6 • 3:07 PM EDT • Business • wcax.com
S&C Electric leases big warehouse at transformed Allstate campus

The deal makes S&C one of the largest tenants at the high-profile office-to-industrial redevelopment in the northern suburb.

chicagobusiness.com logo
Oct 6 • 2:48 PM EDT • Business • chicagobusiness.com
Highmark Health Announces Leadership Transition

/PRNewswire/ -- Highmark Health announced today that its Board of Directors has appointed Karen Hanlon as chief executive officer and president of Highmark...

prnewswire.com logo
Oct 6 • 2:00 PM EDT • Health • prnewswire.com
Ruben Amorim 'Interested' As Joshua Zirkzee Attracts January Interest

AC Milan and Juventus ignite a January transfer battle for Joshua Zirkzee as Ruben Amorim weighs a high-profile reunion to reshape his attack amid ongoing squad rotation.

sports.yahoo.com logo
Oct 6 • 1:29 PM EDT • Sports • sports.yahoo.com
Ukrainian health care teams visit to learn best practices and take their knowledge home

Ten Ukrainian health care professionals visited the Vanderbilt Transplant Center, Vanderbilt-Ingram Cancer Center and the Department of Biomedical Informatics

news.vumc.org logo
Oct 6 • 1:17 PM EDT • Health • news.vumc.org
“Crystal Lake” gave Jason Voorhees actor the hockey mask — but only behind the scenes (exclusive)

Callum Vinson, 12, talks about his transformation into the future masked serial killer.

yahoo.com logo
Oct 6 • 12:00 PM EDT • Entertainment • yahoo.com
US Congresswoman Joins Fight to Keep Cannabis Legal in Massachusetts

Rep. Ayanna Pressley is urging Massachusetts voters to reject a ballot measure that aims to repeal the state’s adult-use cannabis laws.

cannabisbusinesstimes.com logo
Oct 6 • 11:59 AM EDT • Business • cannabisbusinesstimes.com
UCF Honors 8 Trailblazing Faculty with 2026 Luminary Awards

The honorees are advancing discovery across fields ranging from transportation safety and quantum science to tourism, disaster resilience and emerging technology.

ucf.edu logo
Oct 6 • 11:55 AM EDT • Science • ucf.edu
Jackson Health Foundation Celebrates Historic $15 Million Gift From Double-Lung Transplant Survivor Carlos Peralta - Florida Hospital News and Healthcare Report

Carlos Migoya, Silvia Rios Fortun, Flavia Llizo, Carlos Peralta and his wife Mariana, Dr. Mauricio Pipkin, and David Zambrana Transformational donation expands lung ICU and names the Carlos Peralta and […]

southfloridahospitalnews.com logo
Oct 6 • 11:43 AM EDT • Health • southfloridahospitalnews.com
Scientists Just Found a Strange Link Between Cats and Happiness

Countries with more cats tended to report higher happiness, while greater exposure to a common cat parasite was linked to lower scores.

vice.com logo
Oct 6 • 10:37 AM EDT • Science • vice.com
How to watch the Hornets’ preseason opener on Palmetto Sports & Entertainment Network

Charlotte Hornets basketball is back Tuesday night, and Grand Strand fans can watch it.

wmbfnews.com logo
Oct 6 • 10:36 AM EDT • Entertainment • wmbfnews.com
What’s in Trump’s $3.4 Trillion Tax and Spending Bill: 2025 Reconciliation Act

The Senate passed the Protect College Sports Act (S. 4668). Here's what the federal NIL bill means for revenue sharing, transfers, and state NIL laws.

statecapitallobbyist.com logo
Oct 6 • 10:22 AM EDT • Sports • statecapitallobbyist.com
Scientist who hunts mysterious ghost particles in the Antarctic ice wins Nobel Prize for physics

Francis Halzen said it was predicted that he would win the prize, but the announcement still made him feel “strange.” The 82-year-old scientist is affiliated with the University of Wisconsin–Madison in the U.S.

latimes.com logo
Oct 6 • 10:20 AM EDT • Science • latimes.com
McKesson and CD&R to acquire Option Care Health for around $5.8B

The $5.8 billion transaction establishes a framework for McKesson to potentially acquire CD&R's stake.

axios.com logo
Oct 6 • 10:10 AM EDT • Health • axios.com
High-Signal Publisher
Brazil: Lessons from a Disaster

By Antonio Martins (Outras Palavras) Defeats become deeper and more prolonged when we misunderstand what caused them, avoid correcting course, and embrace “solutions” that only compound our mistakes. Lula’s government and the Brazilian left suffered a disaster in Sunday’s election. Contrary to every poll, the president finished the first round 2.2 million votes behind Flávio Bolsonaro—and, more significantly, 3.4 million votes below his total four years ago, when the machinery of the state was working against him and in favor of his opponent. His vote share declined in 98 percent of Brazil’s municipalities. The PL, the main party of the far right, elected 121 deputies and 28 senators, becoming the largest caucus in both houses of Congress. The parties aligned with the Centrão—Brazil’s bloc of transactional center-right parties—were somewhat diminished, but will still hold roughly 250 seats in the Chamber of Deputies and 35 in the Senate. That will make it easier to assemble the majorities needed to amend the Constitution or impeach Supreme Federal Court justices. If elected, Flávio Bolsonaro could appoint four members of the Court, substantially altering its internal balance of power. What produced these results? How can the far right be prevented from consolidating them into a prolonged political hegemony? And what is the essential change of direction the left now needs? Explaining the Disaster Across the commercial media and the exuberant chaos of digital platforms, interpretations are multiplying. Some focus on specific episodes: Lula’s absence from the Globo debate, his very close relationship with Alexandre de Moraes, or his emphasis on issues supposedly remote from most people’s everyday concerns, such as rare earth minerals. Among the more systemic interpretations, three seem especially questionable. One argues that the principal defeat was not the left’s, since its congressional representation declined only slightly. The decisive movement captured at the ballot box, according to this view, was a shift within the right itself—from the more moderate and transactional forces of the Centrão toward the more ideological and radicalized forces of the PL and Novo. A second interpretation holds that the nature of electoral and political processes has changed. The material interests and aspirations of society, it argues, no longer play the central role they once did; they have given way to forms of subjective self-identification that the left has yet to understand. And a third concludes that, because of these two developments, we should expect a political winter: a prolonged period in which the far right and the broader right dominate Brazilian political life. There are important elements in all three interpretations. The problem lies in what they deny or leave out: Lula’s third government was a small-bore government. It offered the majorities that elected it neither a clearly better life nor reasons to believe again in politics and its power to transform society. These failures flowed from two fatal accommodations, which I will examine below. As a result, the government suffered a slow but steady erosion of support. And, as has happened in so many Western countries, it gave the far right the opportunity to present itself as anti-system and to benefit from popular frustration and distress. The interpretation that emphasizes the migration of votes from the center-right and traditional right toward the far right has been advanced, among others, by the courageous journalist Leonardo Sakamoto. In his UOL column on Monday, October 5, he highlights the miserable behavior of the traditional conservative parties. Over the past four years, they repeatedly joined forces with the “neo”-fascists, helping to “normalize” them—a criticism that could equally be directed at almost the entire corporate media. Believing they could use the far right as a stepping stone, they instead ended up partly devoured by it. This was especially true in the Senate, where the PL’s gain of 13 senators and Novo’s gain of two came at the expense of the PSD, which lost nine; the MDB, which lost two; the PSDB, which lost two; and the PP, which lost one. Sakamoto’s observation is accurate and necessary, but it leaves uncomfortable questions unanswered. Why did the erosion of the Centrão benefit the far right rather than, for example, producing growth for the left—as has happened so many times before, both in Brazil and elsewhere? The answer is not difficult. Throughout its four years in office, Lula’s third government was almost invariably associated with the Centrão. Here lies its first accommodation: accepting the limits imposed by conservative institutions; avoiding, as much as possible, any attempt to strain those limits through popular pressure; and believing only in the modest changes that could be squeezed through openings in Congress. The failure of the campaign to end the six-day workweek is emblematic. Lula could have electrified the presidential race by pairing it with a popular campaign for passage of the measure. Instead, he chose to place his hopes in the hands of Senate president Rodrigo Alcolumbre. He generated no mass mobilization, did not force his opponents onto an uncomfortable defensive, and won no victory. In September 2025, the government squandered the greatest of its many opportunities to shake up conservative power in Congress. Popular opposition to the so-called Shielding Amendment—which, if approved, would have restricted criminal proceedings against members of Congress—brought crowds into the streets, mobilized primarily by artists and social movements. This opened the possibility for a broader political education: a campaign that could begin exposing the limits and dysfunctions of Brazil’s political system while putting Bolsonaro’s movement on the defensive for its predictable support of political privilege. The amendment was defeated. But the executive branch then backed away from the fight. It remained associated with an institutional world widely seen as corrupt, elitist, and indifferent to ordinary people’s struggles. In doing so, it forfeited its credibility as a vehicle for the protest vote. On Sunday, it reaped the bitter fruits. Are We Doomed? Taking a different approach from Sakamoto, the philosopher Moysés Pinto Neto and other writers have drawn attention, in their first analyses of October 4, to the fragmentation of the public sphere produced by Big Tech platforms. Through their algorithms, these platforms present each person with a different view of social reality. As a consequence, it becomes much harder to identify common material problems and demands—for example, the fight for labor rights or for a properly funded public health system. Voters no longer embrace such demands, these authors argue, because they no longer see themselves as part of a collective. Instead, they tend to value the identities assigned to them by neoliberal subjectivity—the role of the entrepreneur, for example. On this interpretation, the left’s possible error lies in clinging to outdated illusions. Moysés’s warning is highly relevant and resonates with arguments such as Naomi Klein and Astra Taylor’s “Apocalyptic Fascism and the Billionaires’ Bet.” Unlike a century ago, the far right no longer promises a radiant future. It concentrates instead on resentment—especially that of young men. “They belong to a generation that fears it may never own a home, but compensates with the pleasure it gets from constantly provoking progressives online. Convinced their future has been stolen, they share memes romanticizing historical authoritarian regimes,” the authors write. But Moysés seems to confuse this danger with inevitability. He fails to see that the left’s answer cannot be adaptation. On the contrary, it must strengthen the possibility of politics as collective action. Nor does he recognize that precisely such a reversal is already becoming possible in some of the most promising mobilizations of the twenty-first century: the election, at the end of 2025, of the young Muslim Zohran Mamdani as mayor of New York, on a platform centered on the intensely material fight for an affordable city; the Left Party’s victory in Berlin two weeks ago, built around the demand to expropriate private real-estate corporations; and the very recent wave of demonstrations in Spain—including an occupation of Madrid’s Puerta del Sol—in which tens of thousands of young people mobilized by the Tenants’ Union have demanded limits on rents. By putting itself in the straitjacket of the “fiscal framework” in the first months of 2022, Lula’s third government adopted the second fatal accommodation of its term. Faced with conservative institutions and a country devastated by four years of Bolsonaro, increased public investment was the government’s remaining weapon for offering a more dignified life to the majority and forging an anti-conservative pact with them. The same state that disburses 1 trillion reais a year to enrich a small class of rentiers could instead spend money to extend the Family Health Strategy to every Brazilian, at a cost of 30 billion reais; provide full-day public schooling and childcare to all adolescents and children—and, especially, relief to their mothers; achieve universal sanitation while cleaning up polluted urban rivers; multiply metro systems; begin transforming the urban peripheries; and undertake many other urgently needed projects. In April 2023, an article in Outras Palavras warned that the fiscal framework could “shrink the Lula government and preserve the forces that condemn the country to inequality and regression.” A year later, another article showed that restraints on public spending were strangling policies vital to ordinary people and undermining the president’s popularity. In November 2024 came a reality check, in the form of the government’s humiliating defeat in the municipal elections. Even then, the fiscal lock was neither removed nor loosened. On the contrary: throughout the government’s four years, fiscal restraint remained central to its political narrative. The administration proudly proclaimed that it had “put the state’s accounts in order,” without grasping either how misleading that phrase was—given the payment of 1 trillion reais in interest—or how badly the message was hurting it politically. Lula finally woke up in September 2026. The increase in Bolsa Família benefits, after four years of being frozen; the announcement that anti-obesity drugs would be offered through Brazil’s public health system; and the ban on online betting showed that the state has the power to act decisively on behalf of the majority when those in government are willing to confront obstacles. The huge marches that closed the campaign in Fortaleza, Salvador, Rio de Janeiro, and São Paulo on the eve of October 4 showed how such initiatives can mobilize activists and the broader public. But it was too late—and too little to change the outcome of the first round. History has not ended The possibility of a turnaround in the three weeks leading up to November 25 cannot be ruled out. It will not be simple or easy. Lula must not only make up a deficit of 2.2 million votes; he must also offset the movement of voters who backed other right-wing candidates in the first round, most of whom are likely to move toward Flávio Bolsonaro. Pulling that off will require a broad, grassroots effort to win over voters, potentially reinforced by new initiatives from Lula. The coming hours and days will be decisive. If Bolsonaro’s movement also wins the presidency, the result will create a high-risk situation for Brazilian sovereignty and democracy. The enormous challenges posed by such an outcome would require the left to reexamine, in depth and with a genuine willingness to engage in self-criticism, its political projects—or its lack of them—and its practices. But would that mean we are condemned to the long winter of far-right hegemony that some analyses are beginning to forecast? It is far too early to say, suggests a recent text by Álvaro García Linera, the thinker who served as vice president of Bolivia under Evo Morales. His central hypothesis is that this political current will prove short-lived. At a moment when the entire world is once again talking about sovereignty and protecting national economies, the far right offers a stale, recolonizing neoliberalism. Its submission to the United States is as blatant and pathetic as Flávio and Eduardo Bolsonaro’s overtures to Donald Trump. Its project amounts to something like every man for himself: greater inequality, capitalism without limits, devastation, and supremacism. Will it work? In the United States, just two years into his second term, Trump himself is reaching record levels of unpopularity and may be on the verge of losing Republican control of both the House and Senate in November. Every new beginning is difficult. Whatever the outcome of the second round, the defeats of October 4 show how profoundly the Brazilian left will have to rethink and rebuild. But just as it would be foolish to underestimate the seriousness of its mistakes, it would be equally foolish to conclude that rebuilding a political project is no longer possible. History has not ended. The times are moving faster than ever. Originally published in Portuguese by Outras Palavras. English translation by Eric Blanc; I’ve added the subtitles. More We can’t stop the far right at home or abroad without a revitalized labor movement, which is yet another reason why you should become a sustaining supporter of the Emergency Workplace Organizing Committee (EWOC) — one of US labor’s pivotal bright spots. Relatedly, Jacobin published a short piece of mine reflecting on a decade of Bernie Sanders inspiring a whole new generation of young worker organizers.

laborpolitics.com logo
Oct 6 • 10:08 AM EDT • Politics • laborpolitics.com
Historic Kress building set for new entertainment hub in El Paso

Take a first look inside the transformation of the historic Kress building.

elpasotimes.com logo
Oct 6 • 10:04 AM EDT • Entertainment • elpasotimes.com
Historic Kress building set for new entertainment hub in El Paso

Take a first look inside the transformation of the historic Kress building.

yahoo.com logo
Oct 6 • 10:04 AM EDT • Entertainment • yahoo.com
‘Boy Meets World’ star Matthew Lawrence recalls ‘dysfunction’ on ‘Girl Meets World’

‘Boy Meets World’ star Matthew Lawrence spoke to EW about the ‘dysfunction’ on the ‘Girl Meets World’ set, and his ‘strange’ experience guest-starring on the spinoff.

ew.com logo
Oct 6 • 10:00 AM EDT • Entertainment • ew.com
Oak Hill Bio Names Joerg Hipp Chief Translational Science Officer

Oak Hill Bio has appointed Joerg Hipp, PhD, chief translational science officer, bringing a former Roche neuroscience leader who previously... Read More

citybiz.co logo
Oct 6 • 9:53 AM EDT • Science • citybiz.co
Lucy Smith: “The boundaries of the entertainment business are changing”

The Director of Mipcom Cannes and MIPJunior describes the highlights of next week’s market, which will explore the global transformation of the media business.

senalnews.com logo
Oct 6 • 8:00 AM EDT • Entertainment • senalnews.com
CD&R and McKesson Corporation Sign Agreement to Acquire Option Care Health

NEW YORK & IRVING, Texas & BANNOCKBURN, Ill., October 06, 2026--CD&R, McKesson Corporation (NYSE: MCK) ("McKesson"), and Option Care Health, Inc. (Nasdaq: OPCH) ("Option Care Health") announced today that they have entered into a definitive agreement, under which CD&R and McKesson will acquire Option Care Health, an independent provider of home and alternate site infusion services, for $32.05 per share, reflecting a total enterprise value of approximately $5.8 billion. At the closing of the tran

finance.yahoo.com logo
Oct 6 • 8:00 AM EDT • Health • finance.yahoo.com
2 top European teams show interest in Arsenal winger

Atletico Madrid and Juventus are showing an interest in Arsenal winger Noni Madueke, just over a year after his transfer to north London.Photo by Alex Pantling/Getty ImagesMike McGrath reports for The...

sports.yahoo.com logo
Oct 6 • 6:05 AM EDT • Sports • sports.yahoo.com
We Need More Pro-Trans Politicians. This Group Thinks It Knows How to Get Them.

Talking to Tyler Hack, who leads the nation’s only political action group dedicated solely to getting trans rights supporters elected.

thenation.com logo
Oct 6 • 5:30 AM EDT • Politics • thenation.com
Juventus remains interested in experienced Ligue 1 defender

On deadline day during the last transfer window, Nicolas Tagliafico was confident that he would find a new club after reaching agreements with Juventus and Atletico Madrid.Juventus wanted to sign him ...

sports.yahoo.com logo
Oct 6 • 5:30 AM EDT • Sports • sports.yahoo.com
🙂 Positive (53%)
love
100%
Exclusive: Chelsea wonderkid attracting transfer interest as January decision made

Olutayo Subuloye is rising through the Blues’ youth ranks, and was recently named Under-21s captain

sports.yahoo.com logo
Oct 6 • 4:29 AM EDT • Sports • sports.yahoo.com
Euro dips further as French central bank chief warns the country risks being ‘strangled by interest rates’

Euro extends last week’s 1.2% drop amid French debt fears and political uncertainty in Europe

theguardian.com logo
Oct 6 • 2:44 AM EDT • Business • theguardian.com
Nobel Prize in Physics to Be Awarded in Stockholm

STOCKHOLM (AP) — The Nobel Prize in physics will be announced Tuesday by the Royal Swedish Academy of Sciences in Stockholm. Last year, three scientists won the Nobel Prize in physics for research on the strange behavior of subatomic particles called quantum tunneling that enabled the ...

usnews.com logo
Oct 6 • 2:43 AM EDT • Science • usnews.com
8 Fermented Foods To Add to Your Diet

Fermented foods like pickles and kimchi can help keep your gut health. An expert shares which foods are worth adding to your meals.

health.clevelandclinic.org logo
Oct 6 • 12:02 AM EDT • Health • health.clevelandclinic.org
NYT Strands hints, answers for October 6, 2026

Every hint, nudge and outright answer you need to complete today's NYT Strands puzzle.

mashable.com logo
Oct 5 • 10:00 PM EDT • Technology • mashable.com
Trump uses anti-trans slur against Democratic Senate candidate in South Carolina

Annie Andrews is a physician running against Sen. Darline Graham.

nbcnews.com logo
Oct 5 • 9:07 PM EDT • Politics • nbcnews.com
High-Signal Publisher
Polling shows ban on trans girls in girls' sports could pass in November

Washington state voters will soon weigh in on a ballot measure to ban transgender girls from playing on girls’ school sports teams. The initiative is controversial, but national and local polling suggest it could have enough silent support to pass.

kuow.org logo
Oct 5 • 8:05 PM EDT • Sports • kuow.org
Countries race to provide oral health care for all in 100-Day Sprint across Asia

Twenty Asian countries and areas across the WHO Western Pacific and South-East Asia regions vowed to strengthen essential oral health benefits as part of a “100-Day Sprint” initiative, during the 16th Asian Chief Dental Officers Meeting held from 27 to 29 September in Kota Kinabalu, Malaysia. The meeting marked the midpoint of the 100-day sprint bolstering support for countries to develop essential oral health benefit packages that can be integrated into national universal health coverage plans. Convened by the two WHO regional offices and the Malaysian Ministry of Health as the Secretariat, the meeting brought together national oral health leaders from 20 Asian countries, staff from all levels of WHO, WHO collaborating centres and other development partners. Participating countries and areas included: Bangladesh, Bhutan, Brunei Darussalam, Cambodia, China, Hong Kong (SAR) China, India, Indonesia, Japan, Lao People’s Democratic Republic, Malaysia, Maldives, Mongolia, Nepal, the Philippines, Singapore, Sri Lanka, Thailand, Timor-Leste and Viet Nam. Participants reviewed progress and refined proposals using the WHO Service Package Delivery and Implementation (SPDI) Platform. Countries conducted bottleneck analyses across four key areas: service delivery, workforce, access to essential medicines and health products, and health financing. They identified practical actions to address implementation challenges and refined proposed revisions to their national oral health benefit packages. “There is no health without oral health. Through the 100-Day Sprint, countries are advancing the implementation of the Western Pacific regional implementation plan on oral health and strengthening progress towards universal health coverage,” noted WHO Regional Director for the Western Pacific Dr Saia Ma'u Piukala. Participants identified bottlenecks and proposed workable solutions to strengthen access to essential oral health care through primary health care, sharing experiences and discussing how best to translate policy commitments into feasible and sustainable action at the country level. Malaysian Minister of Health Datuk Seri Dr Dzulkefly Ahmad highlighted the importance of prevention and primary health-care approaches to improve oral health: “Oral diseases can have lifelong consequences, yet many are preventable. By integrating essential oral health care into primary health care and promoting prevention in schools and communities, we can improve oral health across the life course.”The WHO team led by Dr Huong Tran, Director of the Division of Health Promotion, Disease Prevention and Control of the WHO Western Pacific Region and national oral health leads from over 20 Asian countries visited the SK Pekan Putatan School, Sabah for school oral health programme including flouride mouth rinsing. © WHO / V. ChaudharyDr Huong Tran, Director of the Division of Health Promotion, Disease Prevention and Control for the WHO Western Pacific Region, emphasized key collaborative roles WHO can play. “Oral diseases are the most common noncommunicable diseases, yet many can be prevented and treated through essential oral health services delivered at the primary health-care level,” she said. “By sharing experiences and using WHO tools such as the SPDI Platform, countries are accelerating progress towards universal health coverage for oral health.” “Integrating oral health into broader health services is essential for reducing inequities, expanding access and recognizing oral health as an integral component of overall health and well-being. The 100-Day Sprint provides an important opportunity to translate this commitment into practical action and ensure that quality oral health services reach all people, especially those most in need,” said Dr Suman Rijal, Director of the WHO South-East Asia regional Department of Healthier Populations and Noncommunicable Diseases. As host of the meeting, Malaysia showcased ongoing efforts to strengthen oral health care through primary health care and prevention-focused approaches, while providing a platform for countries across the two WHO regions to exchange experiences and accelerate progress towards universal health coverage for oral health. “WHO is encouraged by Malaysia's leadership in addressing the burden of oral diseases and advancing universal health coverage for oral health through practical, country-led action,” said Dr Rabi Abeyasinghe, WHO Representative to Malaysia, Brunei Darussalam and Singapore. Countries will continue to refine and figure costs for national oral health benefits during the remaining sessions of the 100 days. These efforts support implementation of the WHO Global strategy and action plan on oral health 2023–2030, while also helping to expand access to essential oral health services through stronger and more equitable health systems across the WHO Western Pacific and South-East Asia regions.______________For more information, or to arrange media interviews, contact: WHO Regional Office for the Western Pacific: wprocom@who.int WHO Regional Office for South-East Asia: SEMediaRelations@who.int

who.int logo
Oct 5 • 8:00 PM EDT • Health • who.int
Scientists finally see how nature moves energy so efficiently

Researchers have captured key steps in a chemical reaction that helps nature transfer energy with remarkable efficiency. Ultrafast X-rays revealed how changes involving electrons and protons are closely linked to the rearrangement of surrounding water molecules. Because similar reactions drive photosynthesis and other energy-conversion processes, the technique could help scientists develop better catalysts, fuel cells, and flow batteries.

sciencedaily.com logo
Oct 5 • 8:00 PM EDT • Science • sciencedaily.com
UW-led optoelectronic center receives second round of funding from the US National Science Foundation

A University of Washington-led center for optoelectronics — technologies that combine light and electronics — brings researchers from 14 universities across the U.S. together with the mission to develop new materials to transform information technology with light. Founded in 2021, NSF IMOD has received a second round of funding from the NSF to continue its work for the next five years.

newswise.com logo
Oct 5 • 7:15 PM EDT • Science • newswise.com
How the Trump administration's revamped healthcare price transparency rules could impact patients

Consumer advocates say the rules are an important step, but stress there's more work today to ensure full transparency.

wbaltv.com logo
Oct 5 • 6:57 PM EDT • Health • wbaltv.com
How the Trump administration's revamped healthcare price transparency rules could impact patients

Consumer advocates say the rules are an important step, but stress there's more work today to ensure full transparency.

kcci.com logo
Oct 5 • 6:57 PM EDT • Health • kcci.com
Trump uses anti-transgender slur to attack South Carolina Senate candidate

President Donald Trump on Monday used an anti-transgender slur to attack Democratic South Carolina Senate candidate Dr. Annie Andrews, as he tries to push his hand-picked GOP candidate, Sen. Darline Graham, over the finish line in the midterm election.

cnn.com logo
Oct 5 • 6:29 PM EDT • Politics • cnn.com
Deep dive
😐 Neutral (27%)
love
100%
Trump uses anti-transgender slur to attack South Carolina Senate nominee

(CNN) — President Donald Trump on Monday used an anti-transgender slur to attack Democratic South Carolina Senate nominee Dr. Annie Andrews, as he tries to push his handpicked GOP candidate,

kten.com logo
Oct 5 • 6:29 PM EDT • Politics • kten.com
Trump uses anti-transgender slur to attack South Carolina Senate candidate

(CNN) — President Donald Trump on Monday used an anti-transgender slur to attack Democratic South Carolina Senate candidate Dr. Annie Andrews, as he tries to push his hand-picked GOP candidate,

kten.com logo
Oct 5 • 6:29 PM EDT • Politics • kten.com
Deep dive
😐 Neutral (22%)
love
50%
wow
50%
Matt Vioral Joins Brillstein Entertainment Partners As Manager

Matt Vioral has joined Brillstein Entertainment Partners in a transition to management after two decades at Gersh, Deadline has learned.

deadline.com logo
Oct 5 • 6:12 PM EDT • Entertainment • deadline.com
3 takeaways from our new poll of Latino voters: From the Politics Desk

Plus, Democrats’ lingering division over their messaging on transgender issues.

nbcnews.com logo
Oct 5 • 6:00 PM EDT • Politics • nbcnews.com
High-Signal Publisher
Dr. Egnor: The “Platonic Turn” in Science

There is a “disconnect” between a physical organ of the body — the brain — and the “immortal mind,” the human spirit, that transcends it.

scienceandculture.com logo
Oct 5 • 4:52 PM EDT • Science • scienceandculture.com
Teaching students scientific-storytelling skills to inspire change

The senior capstone course ESCI 191 equips environmental-science majors with digital-storytelling skills to translate complex climate data into compelling narratives to immerse and engage the public.

news.ucsc.edu logo
Oct 5 • 4:37 PM EDT • Science • news.ucsc.edu
US says foreign financial institutions doing business with Iran may be sanctioned without notice

WASHINGTON, Oct 5 (Reuters) - The US Treasury Department said on Monday it was alerting foreign financial institutions that continue ‌to do business with Iran or its financial sector that they ‌may be sanctioned by Washington without advance notice. DETAILS: • "Foreign financial institutions continuing to transact with sanctioned ​Iranian financial institutions could be targeted at any time without advance notification and should take immediate action to terminate such activity and relationship

finance.yahoo.com logo
Oct 5 • 4:29 PM EDT • Business • finance.yahoo.com
WATCH: Trump administration issues final rule on transparency in healthcare coverage
pbs.org logo
Oct 5 • 2:50 PM EDT • Health • pbs.org
WATCH: Trump administration issues final rule on transparency in healthcare coverage
pbs.org logo
Oct 5 • 2:50 PM EDT • Politics • pbs.org
New Trump regulations would clean up health care pricing disclosures

The Trump administration is continuing its effort to bring more transparency to the cost of health care.

statnews.com logo
Oct 5 • 2:33 PM EDT • Health • statnews.com
😐 Neutral (0%)
love
100%
University of New Haven Researchers Advance Health Equity and Health-S

Research focused on health equity and health-system transformation has grown from a 2023 faculty-student project into a broad, collaborative body of scholarship involving students, faculty, health sys

newhaven.edu logo
Oct 5 • 2:30 PM EDT • Health • newhaven.edu
Massachusetts Governor Urges No Vote on Cannabis Prohibition Measure

Gov. Maura Healey said she opposes Question 8, a ballot measure that aims to wipe out the state’s adult-use legalization laws.

cannabisbusinesstimes.com logo
Oct 5 • 2:01 PM EDT • Business • cannabisbusinesstimes.com
Agora Realty Starts Construction on Mixed-Use Pro-Level Youth Sports, Sports Tourism, and Entertainment District in North Las Vegas

Marking a major milestone for one of the most transformative developments in the fast-growing city of North Las Vegas, Agora... Read More

citybiz.co logo
Oct 5 • 1:50 PM EDT • Entertainment • citybiz.co
Trump administration finalizes transparent healthcare pricing rules

The rules are intended to make healthcare pricing information more accurate, standardized and easy to use

spectrumlocalnews.com logo
Oct 5 • 1:43 PM EDT • Health • spectrumlocalnews.com
Lightsaber-like plasma antenna uses laser-ionized air to transmit radio waves

Researchers have demonstrated a technique that uses a laser to produce a plasma beam antenna capable of transmitting radio waves. The article, "Laser-Induced-Plasma-Filament Antenna Transmitting 30 MHz ...

phys.org logo
Oct 5 • 1:20 PM EDT • Technology • phys.org
Former UCF RB Harvey Becoming Broncos' Go-To Receiver

RJ Harvey is transforming Denver's struggling offense, leveraging elite elusiveness and savvy improvisation to evolve from a depth tailback into Bo Nix’s most reliable aerial weapon.

sports.yahoo.com logo
Oct 5 • 11:59 AM EDT • Sports • sports.yahoo.com
Can Democrats expand their Senate map?

Plus: Will Ken Paxton's estranged wife help him win?

usatoday.com logo
Oct 5 • 10:47 AM EDT • Politics • usatoday.com
Soldiers wounded in Iranian drone strike say military medical system failed them

The attack on the second day of the U.S. war with Iran killed six troops and injured dozens

spectrumlocalnews.com logo
Oct 5 • 10:34 AM EDT • Politics • spectrumlocalnews.com
DAI Closes HCA Hospice, Home Health Transaction

Deaconess Associations Incorporated (DAI) has closed its acquisition of 31 home health and hospice agencies from HCA Healthcare (NYSE: HCA).

hospicenews.com logo
Oct 5 • 10:30 AM EDT • Health • hospicenews.com
Trump health officials hold make announcement on healthcare price transparency

Watch as Trump health officials hold make announcement on healthcare price transparency.

wknofm.org logo
Oct 5 • 10:27 AM EDT • Health • wknofm.org
Anti-trans ballot measures are a political test run for the 2028 presidential election

LGBTQ+ movement leaders warn that anti-trans ballot measures in five states could become a testing ground for a broader political strategy in the 2028 presidential election.

yahoo.com logo
Oct 5 • 10:00 AM EDT • Politics • yahoo.com
Some mental health providers hoping to serve Lane County's Oregon Health Plan members say they’re facing barriers

Aspire is one of a few healthcare providers in Lane County that told KLCC they want to – but haven’t been able to – get a contract with Lane County's Medicaid insurer Trillium. That’s left Aspire without access to its target population, and other providers considering scaling back their services.

klcc.org logo
Oct 5 • 9:22 AM EDT • Health • klcc.org
Watch live: RFK Jr., Trump officials unveil health care price transparency push

Health and Human Services Secretary Robert F. Kennedy Jr. and Centers for Medicare and Medicaid Services Administrator Dr. Mehmet Oz will announce new efforts Monday aimed at strengthening health c…

thehill.com logo
Oct 5 • 8:55 AM EDT • Health • thehill.com
Health Brief: Exclusive | Inside the new health price transparency rules

Plus: Trump’s checks to Medicare enrollees could complicate year-end health care negotiations,

washingtonpost.com logo
Oct 5 • 8:45 AM EDT • Health • washingtonpost.com
Back to The Ballroom: Yacht Rock Night

On Sept. 29, 2026, the “Dancing with the Stars” ballroom transformed into relaxing vibes and good times for yacht rock night. While there was smooth sailing, the 13 couples experienced some turmoil on the dance floor.

wcuquad.com logo
Oct 5 • 8:01 AM EDT • Entertainment • wcuquad.com
Delta Health Center Receives Funding

Delta Health Center, Inc. has received four awards totaling $4,660,331.59 through the Mississippi Rural Health Transformation Program, a state initiative funded by the Centers for Medicare & Medicaid Services. Governor Tate Reeves announced the four RHTP awards on September 14, as part of 167 awards totaling more than $104 million statewide. The awards announced will […]

deltabusinessjournal.com logo
Oct 5 • 8:00 AM EDT • Health • deltabusinessjournal.com
Delta Health Center Receives Funding

Delta Health Center, Inc. has received four awards totaling $4,660,331.59 through the Mississippi Rural Health Transformation Program, a state initiative funded by the Centers for Medicare & Medicaid Services. Governor Tate Reeves announced the four RHTP awards on September 14, as part of 167 awards totaling more than $104 million statewide. The awards announced will […]

deltabusinessjournal.com logo
Oct 5 • 8:00 AM EDT • Business • deltabusinessjournal.com
Innovation That Solves: From Business Needs to AI Solutions

Targeted AI innovation transforms business challenges like hydrocarbon compliance into effective technological solutions, writes Jorge Mandujano.

mexicobusiness.news logo
Oct 5 • 8:00 AM EDT • Business • mexicobusiness.news
‘An anchor’: Oakshire fans celebrate, grieve as business prepares to shut down

Oakshire Public House has been a gathering space in the Whiteaker neighborhood since 2013 and holds many individual and community memories. Oakshire as a company is closing, but it plans to transition the Public House to a new company in the next two months, keeping the location open through the process.

lookouteugene-springfield.com logo
Oct 5 • 7:26 AM EDT • Business • lookouteugene-springfield.com
Yale School of Medicine On the Science of Childhood Anxiety, Say, Anxiety Disorders Are the Most Common Mental Health Challenges In Youth

Credit: Matt Bradbury October 5, 2026 - By Isabella Backman - Anxiety disorders are the most common mental health challenges in youth. Left untreated, they can disrupt the lives of both children and their families. The good news is that with intervention, most children will overcome these conditions. Across Yale School of Medicine, scientists are working to understand anxiety at every level, from common anxious behaviors to molecular biomarkers in the brain. They are using their findings to develop and disseminate new evidence-based treatments for childhood anxiety. Today, the go-to treatment for childhood anxiety disorders is cognitive behavioral therapy (CBT). This is a form of psychotherapy that teaches children skills for confronting anxious thoughts and helps them practice managing situations that cause anxiety. While it is the gold-standard treatment backed by considerable scientific evidence, up to 50% of children will not see sufficient benefit from CBT alone. Wendy Silverman, PhD, Alfred A. Messer Professor in the Child Study Center, co-directs the Anxiety and Mood Disorders Program alongside Eli Lebowitz, PhD, associate professor in the Child Study Center. One of their main interests is learning how to improve outcomes beyond CBT. “We’re developing cutting-edge, research-based knowledge that can reduce the suffering that anxiety causes children and their families,” says Silverman. Changing parent behavior YSM experts are investigating how to improve CBT outcomes for children by involving the parents. Silverman’s research has uncovered two main components of parent intervention that improve childhood anxiety: not enabling children to completely avoid the things that make them anxious and taking steps to enhance their autonomy. Parents may unintentionally reinforce their child’s anxiety by allowing them to avoid what makes them anxious. They also may unintentionally limit the children’s sense of autonomy by being overly intrusive. “One of the things that we take pride in is that we’ve focused on trying to understand what parents need to do, and to test our ideas and see if changing the parents’ behaviors is enhancing the effects of CBT,” Silverman says. “Our findings thus far suggest that they do." As much as CBT can be helpful, it can also be challenging to get one’s child to do the necessary steps for CBT to work. This is one important reason why Lebowitz created a novel intervention program for parents named Supportive Parenting for Anxious Childhood Emotions (SPACE). Existing intervention programs often teach parents to act as therapists for their child, such as training them on how to practice breathing exercises. “It makes sense, but this doesn’t work very well in practice,” says Lebowitz. “And part of the reason, I think, is that it’s not easy to get your kid to do things, especially if they’re not excited about doing it.” SPACE is unique because it focuses entirely on parent involvement and changing parental behavior—children are not involved in the sessions. For example, parents learn how to use supportive messages that convey confidence that their child can tolerate and manage distress. “It might sound like a parent saying to a child, ‘I get that this is really hard for you, but I know that you can handle it,’” Lebowitz says. The program also works with parents to identify the ways in which they are accommodating anxious behaviors. “We’ll pick one thing that parents are doing that is an accommodation and help them make a detailed plan for how they’re going to change that,” Lebowitz explains. Treating Anxiety in Children and Adolescents Much of the existing research on SPACE has focused on parents of children under age 14. Ongoing studies are now exploring its use with parents of older teens. “Both anxiety and accommodation can interfere with normative developmental shifts during the teen years, including increased autonomy and individuation from parents,” says Rebecca Etkin, PhD, associate research scientist in the Child Study Center. “In this sense, SPACE may be particularly well-suited for anxious teens and their parents. We want to see whether it is effective during this distinct developmental window.” Unfortunately, many families in need of CBT face barriers, including limited availability of services and geographic constraints. One way to improve access is digital interventions. Silverman and her team are developing an evidence-based digitized intervention program for parents that they can access directly from their computer or smart phone. “The work we’re doing will be one of the very few parent interventions that is digitized and importantly tested for effectiveness,” she says. Creating interventions for anxiety-related challenges Silverman and Lebowitz recently received a generous gift to develop and test other interventions that help parents reduce other child anxiety-related behavioral and emotional difficulties, such as restrictive eating and unexplained somatic symptoms. One of these projects in particular focuses on understanding the risks of social media and its potential benefits, including offering a sense of connection. “A lot of research has focused on the idea that social media is harmful and the less of it the better,” says Lebowitz. “But we actually see is that this is not quite right—there are negatives, but there are also positives. So, we’re trying to get a little bit more nuanced of a picture.” The team is working with teens with social anxiety and their parents over an extended period to better understand their social media habits and how their anxiety levels affect engagement with different platforms. The teens will answer questions sent to an app on their phones about mood and social media usage in an effort to capture emotional responses as they unfold. “We hope to develop interventions that can help make the best of social media while protecting against the more problematic effects,” Lebowitz says. The brain’s role in anxiety Researchers are also testing therapies to address anxiety at the neurological and molecular levels. In collaboration with Dylan Gee, PhD, professor of psychology in Yale's Faculty of Arts and Sciences, and Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience at Yale School of Medicine, Lebowitz and Silverman are using brain imaging to identify changes in a child’s brain before and after parents enroll in SPACE. In one study, children viewed anxiety-inducing images while undergoing magnetic resonance imaging (MRI); the researchers conducted scans with and without the children’s parents nearby. Before SPACE, children’s brains were better able to activate the regulatory circuitry needed to turn off an anxious response when their parents were nearby. But after SPACE, children could activate this circuitry even without the parent around. “As parents work on gradually reducing some of their accommodations, you can see a child get better at regulating their own fear system in the brain,” Lebowitz says. “It’s remarkable.” Research into the molecular underpinnings of anxiety can also inform new childhood anxiety treatments. In a recent study, Lebowitz, Silverman, and Flora Vaccarino, MD, Harris Professor in the Child Study Center, discovered that a protein known as fibroblast growth factor 2 (FGF2) could be protective from the toxic effects of stress. FGF2 levels in children and their parents were linked to the children’s risk of developing anxiety and depression, the study showed. The findings could help explain why some children who are exposed to early life trauma such as poverty or abuse are more prone to developing mental health disorders. And FGF2 could be a target for treatment. “This is very novel because it starts to give a clue to what is the molecular chain that connects those lived experiences to the actual psychological outcomes,” Lebowitz says. New ways to study and treat childhood anxiety Michael Crowley, PhD, associate professor in the Child Study Center, collaborates with Silverman and Lebowitz to study the role that attention plays in development and maintenance of childhood anxiety. There is a large body of research that shows that anxious children, like anxious adults, are prone to focus on threatening stimuli such as angry faces compared with neutral faces. This has led to innovative interventions that involve attention retraining. The idea is that if experts train children to look away from threatening stimuli, it may reduce their anxiety—especially children with social anxiety who are most prone to attend to threats. The researchers have just completed a clinical trial for attention retraining with 10- to 14-year-olds with social anxiety disorders and are currently analyzing the findings. Besides this innovative attention retraining research, as Crowly notes, “I like to design tasks that are engaging to kids,” Crowley says. “My goal is to assess something without the kids knowing what we are assessing.” With this goal in mind, Crowley has created a virtual game, named Boom, to study threat processing in children with anxiety disorders. The game is similar to that of hot potato—the child and three digital players take turns virtually passing a ball to each other’s gloves. At some point, the ball turns into a bomb, and as the bomb lands in each player’s glove, the outline of the glove turns yellow. The goal is to avoid having the bomb go off in your glove. What isn’t obvious is that the game is designed to measure different types of threatening stimuli, both ambiguous and direct. In the game, the direct threat occurs as the bomb is traveling towards your glove. The ambiguous threat is the yellow outlined glove as it is unknown where the bomb will travel next. While children play the game, Crowley’s team measures their brain activity using electroencephalography (EEG). The researchers have discovered that in kids with anxiety, the brain reacts more strongly to ambiguous threats than it does in their peers, but less strongly to direct threats. They believe that the initial abnormally large brain response to not knowing where the bomb is going impairs the brain's ability to properly respond when the threat is actually traveling the child’s way. “The brains of children with anxiety are unable to differentiate between threats you need to do something about and those that are not your problem.” Michael Crowley, PhD, develops innovative games for studying anxiety in children and adolescents.Credit: Matt Bradbury Based on these insights, Crowley hopes to study whether interventions like attention training could restore appropriate threat processing. Crowley’s team is also working on a test called the Balloon Risk Avoidance Task, which evaluates risk-taking and avoidance behaviors. It features a digital balloon that is full of air and about to burst. Kids have six seconds to let air out of the balloon. The more air they let out, the less risk they face that the balloon will pop. But at the same time, the balloon becomes less valuable as it deflates. “The more air you keep in the balloon, the more points you get,” Crowley explains. So far, the researchers have found that when the balloons pop unexpectedly, teens with social anxiety show distinct brain responses. Studying these responses can help psychologists understand the underlying pathways driving the various manifestations of anxiety. The genetics of anxiety When Thomas Fernandez, MD, associate professor in the Child Study Center and of psychiatry, was still in training, there was a lot of excitement about understanding the genetics associated with autism spectrum disorder. Since then, scientists have identified around 250 genes associated with autism. The genetic contribution to anxiety disorders, on the other hand, has historically received less attention. Anxiety is less heritable than autism, but the genetic contribution for anxiety disorders that emerge in childhood may be higher than for anxiety disorders overall. While scientists estimate the heritability of anxiety disorders in general to be around 30% to 50%, some studies suggest higher heritability for certain childhood-onset anxiety presentations. “I saw firsthand how researchers in the field went about finding vulnerability genes for autism,” Fernandez says. “So, we’re using a very similar playbook for childhood anxiety.” “I saw firsthand how researchers in the field went about finding vulnerability genes for autism. So, we’re using a very similar playbook for childhood anxiety.” Thomas Fernandez, MD Associate Professor In the Child Study Center and in Psychiatry Now, Fernandez and Emily Olfson, MD, PhD, assistant professor in the Child Study Center, are studying children and their parents to identify genetic changes that are present in the child but not the parents, known as “de novo mutations.” “All of us have some de novo mutations—maybe about 50 to 100 sprinkled throughout the genome,” Olfson says. “But when they occur within the coding regions of genes, they can be really disruptive.” Previous research shows that people with autism have higher rates of damaging de novo mutations than the general population. In 2022, Olfson, Lebowitz, Silverman, and Fernandez published a study on 68 children and their families that found that children with anxiety had similarly high levels of these mutations. Studying de novo mutations can help point the researchers to where they should be looking for genes associated with anxiety. “The end game is using the genes to steer us toward the right part of biology that we can then target to come up with better treatments,” Fernandez says. Building on those findings, the team is now studying more families to better understand how these de novo mutations, along with other genetic and environmental factors, shape pediatric anxiety disorders. They recently received a National Institutes of Health grant to enroll 750 new families over the next five years. Olfson is the principal investigator, with co-investigators Lebowitz, Fernandez, Silverman, and Shuangge Steven Ma, PhD, department chair and professor of biostatistics at Yale School of Public Health. Neurodevelopment, Risk Genes, and Mental Health Conditions - The Olfson Lab Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, is interested in how different anxiety disorders differ genomically. “We are studying social phobia, panic disorder, and generalized anxiety disorder, working to understand why people differ in their risk to these specific anxiety disorders and evaluating various risk factors,” he says. Gelernter was recently involved in one of the largest studies to date of the genomics underlying anxiety disorder. The study included around 122,000 people with anxiety disorders and around 730,000 without. It found that some genetic differences associated with anxiety were linked to signaling that helps reduce overactivity in the nervous system. Many anxiety medications available today work by targeting this process. “It’s nice when the biology that you get out of a large genome-wide study ratifies things that we already know because that can help increase confidence in further findings from the study,” Gelernter says. Uncovering the neurobiology of psychiatric disorders John Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and chair of the Department of Psychiatry, is interested in the neurobiology of psychiatric disorders, including post-traumatic stress disorder (PTSD), of which anxiety is a major symptom. In the late 1980s, Krystal’s team discovered that the drug yohimbine activated symptoms in patients with PTSD. “This was the first time we could link a specific biological mechanism to the symptoms of PTSD,” Krystal says. At the time, he adds, this finding was highly controversial. “A lot of people felt that PTSD was a purely psychological syndrome that didn’t have an underlying biology.” Since then, Krystal has dived deep into understanding the neurobiology of PTSD to learn how to better treat it. His team is evaluating the use of ketamine and psychedelics. These would be among the first treatments to be developed specifically for PTSD. They may also be applicable for other disorders including anxiety disorders, Krystal adds. An important gap in PTSD treatment is the absence of biological tests that inform how to best help patients manage their PTSD symptoms. A doctor doesn’t diagnose cancer based on how they feel. Rather, they use tests of the biology of the cancer to determine the best course of treatment. “And we can’t do that in any psychiatric disorder other than Alzheimer’s disease,” Krystal says. “But now we are building a foundation for this approach to the treatment of anxiety disorders for the first time.” Source: Yale School of Medicine

goldrushcam.com logo
Oct 5 • 6:44 AM EDT • Science • goldrushcam.com
Three sheriff’s offices sign up for jail mental health hold reimbursements under new Wyoming law

The law allows the health department to pay jails for holding and treating people with mental illnesses while they await a bed at the state hospital.

wyofile.com logo
Oct 5 • 6:30 AM EDT • Health • wyofile.com
Deep dive
😐 Neutral (7%)
wow
41%
ahah
32%
love
27%
Rethinking discovery: how powerful screening tools are redefining the search for new medicines

In medicine discovery, identifying the right biological target has always been a critical and complex step. Today, the rise of powerful screening tools is fundamentally reshaping this process, creating a step-change in how we move from scientific hypotheses to transformative medicines. Advances in high-throughput screening, genomics and AI-driven analytics are enabling scientists to interrogate disease biology at unprecedented scale, bringing forward opportunities that were previously beyond reach.

ipsen.com logo
Oct 5 • 5:23 AM EDT • Science • ipsen.com
Buy Rating Reaffirmed Might Change The Case For Investing In Astrana Health Stock

Astrana Health recently reported quarterly results showing solid revenue growth and higher net profit for the period ending June 30, with a reaffirmed Buy rating from Freedom Capital Markets serving as supporting commentary on the business performance. The combination of rising quarterly profitability and revenue momentum suggests Astrana Health is executing on its healthcare model, with analyst confidence reflecting how that operating progress is being interpreted by the market. This...

simplywall.st logo
Oct 5 • 5:12 AM EDT • Health • simplywall.st
Processed meat may be causing rise in bowel cancer

Food safety expert says chemicals in bacon and ham giving them their pink colour are ‘one of the main suspects’

telegraph.co.uk logo
Oct 5 • 5:12 AM EDT • Technology • telegraph.co.uk
The breakthrough is only the beginning

Scientific advances are transforming what's possible in healthcare. But as therapies become more personalized and connected, success depends on what happens after the discovery.

zurich.com logo
Oct 5 • 5:00 AM EDT • Science • zurich.com