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Amazon hiring thousands in Southern Nevada
This year workers will receive a pay bump, with the company putting more than $1.5 billion into wage increases for its United States workers, Amazon said.
Voters in pre-election poll mixed on state of Massachusetts
Many respondents to a new poll believe Massachusetts has become a worse place to live over the past four years and they still favor keeping incumbent Gov. Maura Healey in
Kenny Atkinson Makes Candid Admission About Mario Hezonja’s Cavaliers Role
Kenny Atkinson says Cleveland is still learning how Mario Hezonja fits and does not want to put the returning NBA veteran in a box.
Online student expands domain from sports blogosphere to city hall
Grand Canyon University online student Jon Zaghloul learned about communications from the blogosphere. He started "Sports Talk Chicago," a popular sports blog, and that was […]
‘Healthy Rounds’: Supercharging the Immune System
Dr. Kapil Meleveedu, director of UConn Health’s Blood and Marrow Transplant and Cellular Therapy Program, joins Dr. Anthony Alessi’s podcast
NYC Health + Hospitals/Kings County Celebrates Breast Cancer Awareness Month
Brooklyn, NY – NYC Health + Hospitals/Kings County hosted its annual Breast Cancer Awareness Month Celebration Event, bringing together patients,
76ers Have an Unconventional Formula To Win the Eastern Conference
The offense will be the shiny new toy for this Philadelphia 76ers team. But, it may be their best asset for defense too.
Cognition cofounder: AI race hits 'intelligence saturation' point
Cognition's cofounder says many AI coding tasks are now "intelligence saturated," making cost and speed more important than a smarter model.
I Bought This Low-Mileage Jeep Grand Cherokee For Only $1,700 After Realizing My 'Holy Grail' Project Is Doomed
“David, can you please fix the garage?” my wife Elise asked me on Sunday. “You barely have any time to do house stuff, and today you’re free.” She’s right about the first part — The Autopian really does take up all of my time, and the garage does need to be fixed — but she […]
Ana Navarro shuts down ‘View’ cohosts for joking during tense Donald Trump discussion topic
Ana Navarro shut down ‘The View’ cohosts Sara Haines and Alyssa Farah Griffin for making light of a serious, tense topic related to Donald Trump: ‘Stop, this is not funny.’
Eligible Small Business Customers to Receive October California Climate Credit
/PRNewswire/ -- Eligible small business customers across Pacific Gas and Electric Company's (PG&E) service area will automatically receive a $36.18 California...
Eligible Small Business Customers to Receive October California Climate Credit
Eligible small business customers across Pacific Gas and Electric Company's (PG&E) service area will automatically receive a $36.18 California Climate Credit on their October energy bill. No action is required to receive the credit.
NYC Health + Hospitals/Elmhurst and Queens Public Library Expand Partnership to Bring Health Education and Library Resources to Queens Residents
Elmhurst, NY – NYC Health + Hospitals/Elmhurst and Queens Public Library (QPL) today announced an expanded series of collaborative programs designed to
Six Flags Entertainment (NYSE:FUN) Stock Falls 3.8%
Six Flags Entertainment (NYSE:FUN) Stock Price Down 3.8% - Here's What Happened
Kenya confirms new Ebola case, bringing total infections to 9, health ministry says
Kenya’s Ebola outbreak has risen to nine confirmed cases
Kenya confirms new Ebola case, bringing total infections to 9, health ministry says
Kenya’s Ebola outbreak has risen to nine confirmed cases.
Lucky Strike Entertainment (NYSE:LUCK) Stock Jumps 14%
Lucky Strike Entertainment (NYSE:LUCK) Stock Price Up 14% - Here's What Happened
Axena Health Named Finalist for the Digital Health Hub Foundation - Digital Health & AI Awards 2026 at HLTH
NEWTON, Mass., October 20, 2026--Axena Health, Inc. (Axena Health), a women’s health company redefining the standard of care for pelvic health conditions through clinically proven, non-invasive treatments, today announced it has been named a finalist for the Digital Health Hub Foundation – Digital Health & AI Awards 2026 at HLTH. Selected from a pool of more than 1,300 participating companies across all tracks and categories, Axena Health is recognized in the Best in Class Track for Women’s and
Attack Ad Featuring Candidate’s Mother Turns Ohio Governor’s Race Even Uglier
A Republican ad features Amy Acton’s estranged mother calling her daughter a liar. The two have not spoken since Dr. Acton’s mother backed her husband after his arrest on rape charges.
Pulitzer Prize-winning science author to give lecture at SUNY Plattsburgh
PLATTSBURGH — New Yorker Magazine staff writer and science reporter Elizabeth Kolbert will be on the SUNY Plattsburgh campus for a discussion on how her Pulitzer Prize-winning book, “The Sixth
Kenya Confirms New Ebola Case, Total at Nine, Health Ministry Says
NAIROBI, Oct 20 (Reuters) - Kenya has confirmed a new Ebola case, bringing the total number of infections to nine, the health ministry said on Tuesday. The ministry said the latest case was a close family member of the first patient and had already been placed in quarantine. "All nine cases ...
EXCLUSIVE: SANTOS BRAVOS to return to NYC for one-night-only event at The Paley Museum
SANTOS BRAVOS will appear at The Paley Museum on Nov. 4 for a live music and storytelling event, amNewYork has exclusively learned.
Truist Financial Issues Pessimistic Forecast for Accel Entertainment (NYSE:ACEL) Stock Price
Truist Financial lowered their price target on shares of Accel Entertainment from $14.00 to $13.00 and set a "hold" rating on the stock in a research note on Tuesday.
Giants are releasing running back Najee Harris, AP source says
NEW YORK (AP) — The New York Giants are releasing running back Najee Harris, according to a person with knowledge of the decision.The person spoke to The Associated Press on condition of anonymity Tuesday because the move, which was first reported by NFL Network, had not been announced.
Griffin Gaming Partners launches new joint production company
A prominent game industry fund and Hollywood talent agency are teaming up to adapt games for TV and film.
The surprising conservative backlash against Justice Alito
The Republican justice’s new book has convinced many of his political allies that he’s not entirely on the level.
The Tenacious Collective leads independent artists to New York Comic Con success
Deep within the chaos of the 20th New York Comic Con’s Exhibit Hall sits one of the convention’s largest and most unique booths: the Tenacious Collective.
Time at CSUSM Helps Computer Science Grad Make Forbes' List
Parents usually do anything they can to get their kids to take a break from playing video games. Emily Sorger’s parents took a different approach. “When I was younger, my dad would say, ‘No, you can't go outside and play until you finish this level’ or ‘You can't do your homework until you play this game and tell me if you like it or...
New Tampa Bay business networking group launches
The organization helps connect company founders, executives, advisors and strategic partners.
Exodus Chiropractic celebrates 15 years in business
Exodus Chiropractic celebrated its15th anniversary on Saturday, Oct. 3, with a Williamson Inc. ribbon cutting ceremony.
Conyers TikTok star trades health care career for auto repair and helps train new mechanics
Smoak Power Laboratory honors family’s multi-generational electrical e
Louisiana Tech University's College of Engineering and Science recently celebrated the opening of the Smoak Power Laboratory with a ribbon-cutting ceremony recognizing the generosity of three electric
How Aday Mara's height, weight, wingspan compare to Victor Wembanyama
Aday Mara is being billed as the next Victor Wembanyama stopper, which has led to people comparing their physical traits.
Feeling overstimulated in public? Mental health experts share the strategies that work in any situation
Sensory overload can hit in a grocery store, on a commute or at a crowded party. Here's what therapists and a Harvard psychiatrist recommend, including a few products worth keeping in your bag.
South Korean IPO flop sends rattles top US chip stocks
A tepid debut for Elice, a hotly anticipated South Korean neocloud company, was a fresh hit to AI sentiment on Tuesday.
Berkshire Hathaway Specialty launches in Poland
U.S.-based Berkshire Hathaway Specialty Insurance Company has entered the Polish market, Coverager reported. The company offers a wide range of commercial insurance across Central and Eastern Europe…
Jared Conrad Inks With Sony Music Publishing & TAYCAN Entertainment
Jared Conrad has signed with Sony Music Publishing and TAYCAN Entertainment. Conrad has earned [...]
Live Nation Entertainment (NYSE:LYV) Given Sell Rating at Cfra
Cfra restated a "sell" rating on shares of Live Nation Entertainment in a research report on Tuesday.
JD Vance declines to endorse Netanyahu for reelection, says he's focusing on midterms
“I endorse American candidates, and that’s where I’m focused on the midterms,” Vice President JD Vance said.
GTA 6 Digital Preorders Already Topped 6 Million and $594 Million, With PlayStation Accounting for 74%, Sensor Tower Estimates
Analyst firm Sensor Tower estimates that GTA 6 already sold six million digital copies, eclipsing any other game in the past six years.
Prenosis and Carle Health Mark Sepsis ImmunoScore® Clinical Deployment and First Patients Enrolled in OBSERVE-ARDS Clinical Study
/PRNewswire/ -- Prenosis®, a biology-based technology company delivering precision therapeutics, today announced three milestones in its ongoing relationship...
Republic Business Credit Provides $15 Million Factoring Facility to Temporary Staffing Agency
Republic Business Credit has provided a $15 million factoring facility to an established Midwestern staffing agency. The funding delivers essential working capital to support daily operations, resolve an unexpected liability, and position the Company to execute its long-term growth plans.
Wire 3 Begins Construction on Easley Expansion
Wire 3, a leading 100 percent fiber internet provider, announced that construction is underway in Easley, marking another step in the company’s South Carolina expansion. Powered by a fully funded $19 million investment, the Easley expansion will...
Hartford names wholesale, financial lines leaders
The Hartford on Tuesday named Charles Chin head of wholesale casualty for its Navigators unit and Anthony Dolce head of financial lines, U.S. and global practice for its global specialty business unit.
MCG and Itiliti Health Form Partnership to Support Health Plans with CMS-0057-F Compliance
/PRNewswire/ -- MCG Health, part of the Hearst Health network and the industry's source of truth for trusted clinical guidance, today announced a strategic...
Expanding Iowa State students' poultry knowledge
Dawn Koltes wants to increase Iowa State students’ awareness of the many opportunities available within the poultry industry in Iowa and beyond.
Echo Electric opens Sioux Falls facility
Echo Electric, a Sonepar company and full-line electrical distributor, has opened a location in Sioux Falls.
Peoria indoor baseball and soccer space celebrates 10 years in business
'It just shows that we can do anything here.'
T-shirts and silver balls: Politics get mixed in with the profane at a Trump store
By Elle Reeve, Samantha Guff, Frank Fenimore, CNN Boones Mill, Virginia (CNN) — Walk into Trump Town USA in Boones Mill, Virginia, and you may marvel at the breadth of human creativity, as long as you’re not distracted by how the merchandise tackles some of the most controversial political issues in the most vulgar way
Gentle Brain Ultrasound May Help Ease Delusions in Schizophrenia
NYU Langone pilot study shows that transcranial ultrasound stimulation may safely treat delusions in schizophrenia and schizoaffective disorder. Learn more.
Griffin Gaming Partners and Entertainment 360 launch new company to support video game adaptations for film and TV
HITpoint Entertainment will "combine Griffin's relationships with devs and publishers with Entertainment 360's producing track record on IP-driven franchises"
Schalmont girls' soccer eyes a 7th straight Section 2 title
Schalmont is one of the top seeds for the Section 2 tournament.
Law & Order: College Basketball — How the NCAA's eligibility rules have created chaos before the season's even begun
As the college basketball season quickly approaches, many schools are still trying to fill out their rosters as they navigate legal challenges to NCAA eligibility rules.
People who've finished Call of Duty: Modern Warfare 4 on the new YOLO, single-life difficulty share experiences and tips for doing so
In COD: Modern Warfare 4's new YOLO difficulty, any game over screen takes you back to the very beginning of the game. But there are some tips for beating it.
'Office Space' star Richard Riehle dies at 78
Actor Richard Riehle arrives at the premiere of New Line Cinema's 'A Very Harold & Kumar 3D Christmas' at Grauman's Chinese Theatre on November 2, 2011 in Hollywood, California. (Jason Merritt/Getty Images)Richard Riehle, known for his role in the 1999 film Office Space, has died. He was 78.A statement shared by Artists & Representatives and Wright Entertainment, Inc. announced Riehle's passing on Monday, writing, "Our industry has lost an exceptional talent, and our community has lost a truly wonderful man.""We are deeply saddened to confirm the passing of our beloved client, Richard Riehle, this past weekend," the statement said. "A remarkable actor whose career in theater, film, and television spanned nearly five decades and more than 400 projects, Richard leaves behind an extraordinary legacy."The statement continued, "Beyond his immense talent, he will be remembered for his genuine goodness, boundless kindness, and unwavering generosity, particularly toward emerging actors and filmmakers, whom he encouraged and supported at every opportunity."Born on May 12, 1948, Riehle starred in many television series and films over the years.Notable projects include Casino, The Man from Earth and Deuce Bigalow: Male Gigolo.He got his start as an actor at the University of Notre Dame, where he was involved in the University Theatre and starred in several stage productions. He went on to earn a Master of Fine Arts in acting and directing from the University of Minnesota.While he's played characters that have an "average Joe" presence, he always made the most of his brief screen time.Some roles that he is remembered for include The Quartermaster in Glory, the train guard in The Fugitive, Reverend Scroggins in Fried Green Tomatoes and Bill Cozbi in Bridesmaids.On television, he starred as Principal Ed Rooney in the 1990 series Ferris Bueller and as grandfather Walt Finnerty in the early 2000s sitcom, Grounded For Life.In 2023, he also played Warden Reynolds in Barry.Riehle is survived by his wife, Jane Latham, and their four children.Copyright © 2026, ABC Audio. All rights reserved.
Experian Health Acquires eInsights, Expanding Insurance Discovery to Help Healthcare Organizations Recover Missed Reimbursements
COSTA MESA, Calif., October 20, 2026--Experian today announced its acquisition of eInsights, a healthcare technology company.
‘SIX’ Provides Lively History Lesson
Anyone who has seen “Hamilton” has doubtless thought, “Why can’t we learn all of our history from theater performances?”
Planning commission lauds work on ‘complex’ Lake Fairfax Business Center development plan
Plans to transform most of the Lake Fairfax Business Center in Reston into a mixed-use neighborhood are heading to the Fairfax County Board of Supervisors for a final vote. Developer EYA secured a supportive recommendation from the Fairfax County Planning Commission last Wednesday (Oct. 14) after its legal representative confirmed that any lingering disagreements with
Too Lost’s latest expansion is a deal with Xelon Entertainment
Distributor and tech firm Too Lost's ambitions in the APAC region continue. It acquired Australian distributor and artist-services company Gyro·Group in July, and now it has announced a partnership with another distributor, Xelon Entertainment.
KFF Tracking Poll on Health Information and Trust: Fall 2026 Update on Vaccine Views
The latest KFF Tracking Poll on Health Information and Trust finds about half of parents mistakenly believe spacing out vaccines is healthier for children, while confidence in many long-standing childhood vaccines is high across partisans. These findings take on new relevance following President Trump's recent executive order calling for changes in U.S. childhood vaccine recommendations, including splitting the measles, mumps, and rubella (MMR) vaccine—currently given as a single combined shot—into three separate vaccines across multiple visits.
At $10,000, Would You Race To Buy This 1987 Chevy Sprint Turbo?
Known by many names, but rarely found in such mint condition.
GE Stock Slides Despite Higher Guidance As Costs Rise, Insurance Business Swings To A Loss: CEO Says Company Continues To 'Build Momentum'
GE Aerospace reported third-quarter EPS of $2.25 and revenue of $13.3 billion, beating Wall Street’s estimates.
Start-Up Claims to Treat a Patient With A.I.-Created Viruses
Certain viruses attack bacteria and can sometimes clear antibiotic-resistant infections. Researchers said they had tailored a virus to attack one patient’s illness.
Tecsys delivers AI capabilities to help health systems anticipate and act on pharmacy and supply chain risks
/PRNewswire/ -- Tecsys Inc. (TSX: TCS), an industry-leading supply chain management company, today announced the availability of AI solutions that help health...
NC State a touchdown favorite at Stanford
NC State is making its first trip to Stanford since the Cardinal joined the ACC, which is to say that we’re in for a very late night of who-knows-what. Should be fun. The Wolfpack is a seven-point favorite to win this one, and if there’s any sort of turnaround on the horizon for this group, […]
Shipping dates for the iPhone Duo have been pulled forward for many users
Shipping estimates for the Duo are showing as January 22, but some people who pre-ordered have seen the initial date be pulled forward by weeks or even months.
How Much Of Cisco Stock's Rise Did The Business Earn?
Cisco Systems (CSCO) supplies businesses and the hyperscalers building AI infrastructure with networking and security products, along with services. The company's stock climbed 92% between late July 2021 and mid-October 2026, before dividends. A rally of that magnitude makes it natural to credit a growing business. So take a guess: how much of that rise came from Cisco selling more.
Yankees' Aaron Boone Decision Isn't What it Appears
The New York Yankees have decided to keep Aaron Boone, but it isn't what it appears.
'We used to go to the climate conferences together. We are not anymore': ESA official Simonetta Cheli tells us how the political landscape for Earth observation is changing
Live Science sat down with the European Space Agency's Simonetta Cheli to discuss the importance of Earth observation, how NASA budget cuts have changed the picture, and how the proliferation of private satellites could hinder our ability to view the planet.
Ambetter Health Announces 2027 Marketplace Offerings, Including Enhanced Condition-Specific Coverage Options
/PRNewswire/ -- Ambetter Health, the Health Insurance Marketplace product of Centene Corporation (NYSE: CNC), today announced its 2027 Marketplace offerings,...
Betterworks Named an Inc. Power Partner for Second Consecutive Year
Betterworks, a leading enterprise performance management platform, has been named a 2026 Inc. Power Partner Awards winner, recognizing the company among the ...
Brightstar Capital Partners Invests in Material Handling Group, a Technician-Led Provider of Material Handling Equipment and Aftermarket Services
CANTON, Mich. & NEW YORK, October 20, 2026--Brightstar Capital Partners ("Brightstar"), a private equity firm focused on partnering with founders, entrepreneurs, and management teams, has acquired a majority interest in Material Handling Group USA ("MHG" or the "Company"). Financial terms were not disclosed. MHG is a technician-led provider of new, used, and rental material handling equipment and aftermarket parts and service, serving customers across Michigan, New York, and the Mid-Atlantic reg
A note to readers: Science, accountability and elections
Dear readers, As early voting begins, I wanted to share some news — and why it connects to the decisions we make at the ballot box. I’ve been selected for the inaugural cohort of the South Atlantic Climate Journalism Hub mentorship program, hosted by Covering Climate Now. I’m excited to join this group, learn from scientists and fellow journalists, and expand my science reporting. Science directly ties to governance. Local officials make decisions about where development goes, how infrastructure is maintained, what emergency preparations receive funding, and how communities rebuild after disasters. Understanding the evidence behind those decisions helps us evaluate whether our government is serving us well. Here in western North Carolina, those connections are all around us, in Lake Lure and beyond. Flood maps inform decisions about property and development. Engineering assessments help identify risks at dams and bridges. Rainfall forecasts guide emergency preparations. Geological information helps explain landslide hazards. Water testing gives communities information they need to assess conditions. Meteorologists’ knowledge and public perception of weather events shape public safety. Each involves scientific or technical knowledge. Each also raises questions about public responsibility: What did officials know? How did they use that information? What did they tell the public? What did taxpayers receive for their money? A study can identify a problem. Elected officials still have to decide what to do about it, how to pay for it, and how to explain their choices. Reporting should examine both the evidence and the response. That is where I want to strengthen my work. My reporting on Helene recovery, infrastructure, flooding, public safety, and public spending has repeatedly brought me to questions that require scientific expertise alongside public records. This mentorship may help me better understand the research, ask more precise questions, and explain the answers clearly. I also bring the perspective of someone living with these concerns. I live downstream of Lake Lure Dam, and landslides affected my property during Helene. Those experiences bring urgency to my questions. Careful reporting helps establish the answers. Readers deserve to know what the evidence shows, where uncertainty remains, and whether officials accurately describe the information guiding their decisions. You also deserve scrutiny of proposed solutions: what they cost, what they are expected to accomplish, and what risks remain. Access to that information matters. As a mostly deaf journalist who relies on written communication, I will continue pressing for written public warnings, records, and explanations that people can read and use in real time. As you consider the candidates seeking your vote, consider how they approach evidence, preparedness, and transparency. Do they support local journalism, even when it’s not parroting a press release? Do they explain weather events clearly in plain English and explain their decisions after them? Make supporting records available? Acknowledge uncertainty? Follow through when a report identifies a risk? Those are practical questions about governing. Thank you for supporting Cops & Congress and the work that makes these questions part of the public conversation. I’m grateful to David Dickson and the CC Now team for this opportunity, and I look forward to bringing what I learn back to you. Annie DanceEditor & Publisher, Cops & Congress — Learn more about this newsletter, ethics policy, how you can help shape this work, and support it. Follow on X and Facebook. Send constructive criticism, fan mail, and tips with public documents for future stories: CopsandCongress@gmail.com ICYMI: View the Cops & Congress archive — Annie Dance is the publisher of Cops & Congress, a newsletter that analyzes what happens when crime, courts, disaster, democracy, and small-town policies collide. Views expressed here are covered by the First Amendment. Dance has a Bachelor of Arts from Manhattan University in Communication with a focus in Journalism and Government. She has been a journalist for over 20 years. Share Upgrade now or give a gift subscription
Bill Nye "The Science Guy" makes surprise appearance in Rutherford County
Nashville News, Weather, and Sports
Bungie plans to share first details about surprise 'unvaulting' of Destiny 2 content soon
We should learn more about Bungie's 'unvaulting' of previously removed Destiny 2 content very soon.
Kratos Would Have Had a Different Name Were It Not for Relentless Domino's Pizza Jokes, God of War Creator Reveals
God of War's Kratos almost went by a different name, but developers at Santa Monica Studio made too many Domino's pizza jokes.
GM’s core profit rises 22% on strength of pickup-truck business
By Kalea Hall Oct 20 (Reuters) - General Motors’ third-quarter results easily beat analyst expectations on the back of resolute shoppers who continue to spring for pricey pickups and SUVs. The company on Tuesday said quarterly earnings before interes...
I’ve used the Pixel 11 Pro XL and iPhone 18 Pro Max, and Apple’s ecosystem isn’t enough anymore
I've used iPhones for almost two decades, and much of what made Apple's devices an easy choice has eroded.
What to know about the two candidates in Wisconsin's 7th District
Republican Michael Alfonso and Democrat Fred Clark are squaring off in the 7th Congressional District. The winner will succeed Tom Tiffany.
Owner of CT information technology consulting business sentenced for computer intrusion scheme
Federal officials said he remotely disabled a client’s computer network on 21 separate days in 2024, which resulted in the company being unable to conduct business on those days.
Gen Z founders want lean teams, but they still crave coworkers
I visited a NYC office full of Gen Z startup founders and discovered why building a company with AI doesn't always mean wanting to work alone.
Hisense Awarded Dubai Chamber ESG Label, Recognizing Sustainable Business Practices in the UAE
/PRNewswire/ -- Hisense Middle East has been awarded the Dubai Chamber ESG Label, an important recognition of the company's commitment to responsible and...
France Protests Show Europe’s Shift Away From Centrist Politics
Europe’s centrist parties are losing ground among young people and workers, who are increasingly tempted by populist promises of radical change.
So What Is Socialism, Anyway?
In a world dominated by neoliberal market fundamentalism, “socialism” is what will make a more moderate, regulated form of capitalism work for most people.
JCPS paid $292K for an online mental health service. Six kids used it.
The company is one of hundreds of ed tech providers that have contracted with JCPS
"This act is intended to demonstrate solidarity with Palestine" - Umurangi Generation studio blocks new game Penguin Colony from being sold in Israel
"In the absence of more organised sanctions," Umurangi Generations studio Origame has blocked the sale of its new game Penguin Colony in Israel.
Scientists think they've worked out why anything exists at all. Is this the answer to the oldest problem in the Universe? | BBC Sky at Night Magazine
Could scientists have finally found the particle that explains why matter triumphed over antimatter and why anything exists at all?
Records reveal why AI political ads raise alarms in NY
The USA TODAY Network obtained records from state agencies tasked with overseeing AI uses in elections. See what it means for 2026 midterms.
Pfizer makes ‘business decision’ to end phase 2 trial of autoimmune drug as program’s future uncertain
Pfizer has called time on a phase 2 trial of its CXCR5 antibody in an autoimmune blood disorder, with the company tight-lipped on whether this marks the end of the road for the asset. The Big Pharma had been evaluating the therapy, dubbed PF-06835375, in a phase 2 study of 61 patients with primary immune thrombocytopenia (ITP) that kicked off in 2022, according to the federal trials register. However, Pfizer confirmed to Fierce on Monday that this study had been terminated “due to a business decision.” “The decision to terminate the trial was not based on any safety concerns,” a spokesperson pointed out. At time of publication, PF-06835375 remained listed on Pfizer’s website for both ITP and lupus. A phase 1 study in lupus wrapped up in 2022, according to the trials database. ITP is an autoimmune disorder characterized by a low platelet count. Novartis was at one point evaluating its B-cell-depleting antibody ianalumab—recently approved as Fabhalta to treat immunoglobulin A nephropathy—as a potential treatment ITP. But the therapy struggled to demonstrate a benefit in the clinic for this indication. When contacted by Fierce, Pfizer wouldn’t confirm whether all work on PF-06835375 has been halted, and whether the company has any other plans to explore C-X-C chemokine receptor type 5 (CXCR5) as a mechanism. CXCR5 is found in blood cancers such as diffuse large B-cell lymphoma and mantle cell lymphoma chemokine receptor. However, there is little expression in normal tissue, which has led some drug developers to explore its potential. Vincerx Pharma had at one point been planning to take an anti-CXCR5 ADC into the clinic to treat B-cell malignancies, but that ambition was scrapped due to cash constraints. Where Big Pharma is placing its bets is one of the hot topics being discussed at Fierce Biotech's high-impact event in London next month. Find out more information and register by clicking on the banner below: [ ](https://qtxasset.com/quartz/qcloud5/media/image/where_big_pharma_is_placing_its_bets.png?VersionId=B8JrRbJ.pFUSK1pJgjeWHLGm_18RdLAy)
Pedri: Lamine Yamal shouldn't be compared to Lionel Messi
Pedri believes Lamine Yamal should not be compared to anyone, insisting that measuring the youngster against Lionel Messi is "complicated" because it means comparing him to "the best player in history...
9,450 Shares of Live Nation Entertainment, Inc. $LYV Bought by Cordatus Wealth Management LLC
Cordatus Wealth Management LLC acquired a new stake in shares of Live Nation Entertainment, Inc. (NYSE:LYV - Free Report) during the 3rd quarter, according to the company in its most recent 13F filing with the Securities & Exchange Commission. The institutional investor acquired 9,450 shares of
New-to-science seahorse is one of three long-misidentified species
Scientists have identified a new-to-science seahorse species from the Indian waters, which has helped resolve the taxonomy of a group misidentified for over a century. In 1856, zoologist Johann Jakob Kaup described the thorny or spiny seahorse, Hippocampus histrix, based on samples from Japan. Since then, this seahorse has been thought to be a single, […]
1,906,905 Shares in Tencent Music Entertainment Group Sponsored ADR $TME Bought by Assenagon Asset Management S.A.
Assenagon Asset Management S.A. acquired a new position in Tencent Music Entertainment Group Sponsored ADR (NYSE:TME - Free Report) in the 3rd quarter, according to the company in its most recent disclosure with the Securities & Exchange Commission. The fund acquired 1,906,905 shares of the comp
Can Real Estate Out-Organize Tenants in New York? This Group Will Try.
A new organization, Built for New York, plans to raise money to mobilize voters in the real estate industry, which has endured several political losses in recent years.
Roland n/vision Review: Vision for the Future or Late to the Party?
The new Roland n/vision is the company’s first true wavetable synth. Can the latest addition to the Boutique series hold its own against the competition?
Earnings To Watch: Elevance Health (ELV) Reports Q3 Results Tomorrow
Health insurance provider Elevance Health (NYSE:ELV) will be reporting results this Wednesday before market hours. Here’s what investors should know.
Tencent Music Entertainment Group Sponsored ADR (NYSE:TME) Stock Now Rated "Hold" by Wall Street Brokerages
Tencent Music Entertainment Group Sponsored ADR (NYSE:TME - Get Free Report) has been given an average recommendation of "Hold" by the thirteen ratings firms that are covering the stock, MarketBeat Ratings reports. Nine analysts have rated the stock with a hold recommendation, three have issued a bu
College students more likely to vote this election; Ohio State political leaders and experts reflect on why that is
With midterm elections less than a month away, college students are more likely than ever to head to the polls and cast their votes, new data suggests. As many as 66 percent of college students will vote in the 2026 midterms, according to an August survey conducted by the Center for Information and Research on […]