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News | SP Energy Networks takes 50,000 square feet at Knowsley Business Park
The letting completes Redsun Projects' speculative industrial development
Precision for All: Closing the Gap Between Science and Life
Biopharma innovation is moving fast, yet according to Ryan Keeling, CEO of Diaceutics, the industry continues to face a fundamental challenge: too many eligible patients never reach the therap | Why are so many eligible patients still missing the therapies designed for them?
Trump says he'll consider releasing 9/11 records after families' request
President Donald Trump said Sunday that he will look into requests from families of Sept. 11 victims to release records that could shed light on Saudi Arabia’s alleged role in the attacks 25 years ago.
UH gets $3.6M grant to study health risks from state’s plantation-era contamination
A University of Hawaii at Manoa-led research team has received a five-year, $3.6 million National Institutes of Health grant to investigate whether pollutants left behind by Hawaii’s plantation era still could be affecting residents’ health — and whether wildfires and other natural disasters can bring those contaminants back into the environment.
Riize to release 2nd studio album next spring
K-pop boy group Riize will release its second full-length album in spring 2027, preceded by a prologue single next month, SM Entertainment, the gro...
B.J. Green II suffers elbow injury in Week 1
B.J. Green II exited with an elbow injury and he was unable to return
Trump downplays the need to check AI development and says he doesn't want to cede edge to China
While acknowledging the need for some regulation, Trump provided no specifics about potential rules and attributed warnings about the technology moving too quickly and with little oversight to “negative forces” he did not identify.
UK PM Burnham to meet business leaders to discuss growth
British Prime Minister Andy Burnham will meet the bosses of several major companies on Monday to discuss his plans to generate economic growth, his office said.
Orlando Bloom has spoken with Johnny Depp about reuniting for a new ‘Pirates of the Caribbean’ movie
While speaking with EW at TIFF to promote his strange new drama, ‘Bucking Fastard,’ Orlando Bloom confirmed he has spoken with ‘amazing’ Johnny Depp about reuniting for a new ‘Pirates of the Caribbean’ movie.
Diablo IV x The Witcher III: Wild Hunt Collab Unveiled, Here's A First Look
As part of a new partnership between Blizzard & CD Projekt Red
Trump dismisses AI leaders’ calls to slow down, citing Chinese competition
Democrats are increasingly attacking the administration’s hands-off approach to artificial-intelligence regulation as midterms approach.
Faith-based film productions are thriving in Sacramento. It’s part of a trend
The Sacramento region has long sought to attract film productions. One genre that is thriving in the region: Faith-based films.
What Connects the Last 5 US Open Men’s Champions
Five different men have lifted the US Open trophy since 2020. Their games look nothing alike - Daniil Medvedev's flat, defensive counterpunching has little in common with Carlos Alcaraz's explosive shot-making. There might be some more similarities between Novak Djokovic's clinical baseline and Jannik Sinner's mechanical precision, but they are hardly simulacrums of each other. …
New poll reveals 1 party with huge advantage in 2026 midterms. And it’s bad news for Trump.
The Quinnipiac University poll, released Thursday, found that Democrats have an 11-point edge over Republicans when voters were asked which party they would want to see in control of the House.
Jordan's Review: Auburn takes care of business in home opener
The Auburn Tigers are 2-0, which should create a sense of positivity among the Tigers' fan base.
Scientists used centuries-old aurora sightings to reconstruct 8 solar cycles from 1560 to 1640; their method placed solar minima within 2 years with more than 90% reliability
Centuries-old reports of strange lights in the night sky have helped scientists reconstruct a missing chapter in the Sun’s history. A study published in Scientific Reports by Kristof Petrovay, Laura G.
An unprecedented El Niño sends scientists scrambling for answers
Scientists hope a fleet of Saildrones will help answer questions about how El Niño forms before the next major climate event.
SOSRiverBoy III showcases local talent; brings fun entertainment to Fort Smith
FORT SMITH -- An annual concert and community event will return for the third year in a row when SOSRiverBoy III is held Nov. 28 at the Fort Smith Convention Center.
Forsaken Kingdom Fills a Long-Standing Warcraft III Gap, Adding 30 Hours of Story Between Arthas and World of Warcraft
Warcraft III Reforged: Forsaken Kingdom is out now, adding a 30-hour campaign, Definitive Edition graphics, a new tavern hero, and more.
Police: Huntington Station deli hit with a dozen health code violations
Police say the deli's manager, Carla Rodriguez-Romero, was cited for one ABC Law violation and 12 health code violations.
Benin bets on turning its cotton crop into clothes at home
The fabrics made by Fatoumata Dosso carry the tag “Made in Benin.”
Man wanted on several warrants arrested near Colorado Springs business
A man who was wanted on several warrants was arrested Friday night near a business in Colorado Springs, according to police.
Governor Candidate Keisha Lance Bottoms (D-GA) on Reproductive Health Care
Georgia Democratic gubernatorial nominee Keisha Lance Bottoms delivers remarks on reproductive health care rights in Atlanta.
StarCraft 3 Set for 2030 Release
A new open-world shooter "StarCraft" game is set to debut in 2030 from Blizzard Entertainment.
StarCraft 3 Set for 2030 Release
A new open-world shooter "StarCraft" game is set to debut in 2030 from Blizzard Entertainment.
Power & Politics: Caldwell investigation; 9/11
Democratic strategist Dan Bryan, Republican strategist Jeanette Hoffman and Sept. 11 survivor Brian Branco join the show this week.
Power & Politics: Caldwell investigation; 9/11
Democratic strategist Dan Bryan, Republican strategist Jeanette Hoffman and Sept. 11 survivor Brian Branco join the show this week.
Why Celtics Signed and Cut Former Division III Star
There's a simple explanation for Boston's roster decision.
In 1996, NOAA scientists pumped 2 dyes beneath Key Largo to learn where groundwater went; 18 days later, 2 bay-side wells showed it flowed toward the Atlantic
By the mid-1990s, seagrass die-offs and deteriorating water quality had caused coral reefs throughout the Florida Keys to show signs of decline for years, leading scientists to search for explanations other than the apparent ones like boat traffic and coastal development. One notion that kept coming up among academics investigating the region was that contaminants and nutrients could be carried directly into the reef tract by groundwater seeping silently beneath the islands, where no one could witness it.
Crypto billionaires give $97 million to Reform UK, fueling concerns about money in politics
LONDON (AP) — Reform UK, the anti-immigration party led by Brexit campaigner Nigel Farage, received 72 million pounds ($97 million) from two cryptocurrency billionaires this weekend, fueling …
Warcraft III: Reforged Gets A New Campaign Today, Alongside New Graphics Mode
The real-time strategy side of Warcraft got an update today, including a new campaign and graphical update. - Game Informer
Why Wild Blueberries Stand Out for Heart, Gut, and Brain Health Benefits
A new study claims that wild blueberries are powerhouse when it comes to brain, heart, and gut health—here’s what experts have to say.
Missouri should make medical respite part of its health care infrastructure
Missouri’s healthcare system routinely pays for a hospital stay, a surgery or a course of treatment, then reaches the edge of its own plan when the patient has no home in which to recover. For a person experiencing homelessness, “discharge” can mean returning to a shelter, vehicle or street while managing a wound, infection, cancer […]
President Trump Remarks to U.S. Embassy Personnel & Business Leaders in Ireland
President Trump delivers remarks to U.S. embassy personnel and business leaders in Ireland.
Laredo opens new mental health unit facility downtown
The city of Laredo and police cut the ribbon on a new facility on the 1500 block of Washington Street.
Bengals Injury Update: Latest DJ Turner Health Status Revealed Ahead of Buccaneers Game
All eyes are on two Bengals defenders amidst Friday's final Week 1 injury report. Cornerback DJ Turner II (hamstring) and defensive end Shemar Stewart (knee) b
Tennille cafe celebrates one year in business
Scoot’s Cafe and Ice Cream Emporium was created when co-owners Robert Fisher and Rose Holton combined their separate businesses, a cafe and an ice cream shop, after both faced difficulties on their own.
UK Business Calls For Scrapping Taxes on Electricity Bills
UK business groups urge Chancellor John Healey to scrap electricity levies, warning high energy costs threaten industry competitiveness.
Asian Captive Conference 2026 Highlights How Captives Are Utilised as Businesses Navigate Risks
The 8th Asian Captive Conference (ACC) 2026 yesterday brought together more than 300 risk and industry professionals from the region and beyond to explore how captive insurance is enabling businesses to refine their risk management strategy amid an uncertain and multi-faceted operating environment. The conference was co-organised by Labuan IBFC Incorporated Sdn. Bhd. (Labuan IBFC Inc.) and the Labuan International Insurance Association (LIIA).
Matson tops Hawaiʻi's Most-Profitable Companies List for 5th Year
Despite a 6.6% decline in profits last year, Matson still came out on top, reflecting its unique niche in the shipping world.
Chandigarh University's Computer Science Engineering Students Develop AI-Powered Platform to Detect Fraudulent Apps
Chandigarh University's Computer Science Engineering (CSE) students have once again proven their brilliance on the national stage by securing second position in the national-level CyberShield Hackathon, organized by Bank of India in collaboration with IIT Hyderabad to solve AI, cybersecurity and banking-fraud challenges, winning a prize of Rs 3 lakh by providing innovative solution for harnessing Generative AI for automated reverse engineering, static and dynamic analysis and risk scoring of fra
Pleasanton police investigating string of predawn business burglaries
Pleasanton police are investigating multiple burglaries that took place before dawn on Thursday. Nearly 20 businesses, mostly restaurants, were broken into. Investigators believe this is the result of the same crew of burglars.
Under Night In-Birth II Sys:Celes DLC character Zohar launches September 15 for PS5, PS4, and PC, September 23 for Switch
Under Night In-Birth II Sys:Celes downloadable content character Zohar will launch on September 15 for PlayStation 5, PlayStation 4, and PC, and September 23 for Switch, publisher Arc System Works …
Thursday injury report for Carolina
Panthers LB Patrick Jones II, DT Bobby Brown III on second injury report of week
Festivals of Aloha brings Aloha Friday to Queen Kaʻahumanu Center on Sept. 11
Festivals of Aloha continues its 2026 season with Aloha Friday at Queen Kaʻahumanu Center on Friday, Sept. 11, from 5 to 8 p.m. The free, family-friendly evening invites the community to kick off the weekend with live Hawaiian entertainment, cultural demonstrations and activities for the entire ʻohana.
Entertainment: Hawaii Theater Project launches
A local theater lover is helping other passionate artists connect by launching the Hawaii Theater Project.
What Does the Future Hold for Par Pacific's Refining Business?
PARR benefits from strong refining margins, firm fuel demand and tight inventories, though the Hawaii turnaround may curb near-term throughput.
The Baltic Powers Available Now for Age of Empires III: Definitive Edition! - Age of Empires
Hello adventurers, a Shipment from the Home City has arrived! The Baltic Powers DLC for Age of Empires III: Definitive Edition is available now, and comes
Opinion: What Chicago needs to understand about its climate resilience
No place on Planet Earth is immune from the impacts of a warming planet. And in an interconnected global economy, there is no “climate haven.”
Manhattan business listed as victim of $19,425 embezzlement
Kaw Valley Greenhouses listed as victim in the case.
Science Lab: Christian Parker’s task is tall, Cowboys' window is small
The 2026 season arrives with lots of pressure for the Cowboys, and that includes Christian Parker's defense being up against a shrinking offensive window in Dallas.
Professor Layton and the Curious Village Remake Announced, Coming to Multiple Platforms in 2027
A Professor Layton and the Curious Village remake has been announced by series developer Level-5.
Science and music come together at Oregon State University’s third Big Fish Fest
Oregon State University’s Big Fish Fest III combines live music with shark and bird dissections to teach ocean conservation and science through art.
Final Fantasy 7 Revelation's Director Says He Wanted To Show 'That Final Fantasy Doesn't Have To Be A Traditional-Style JRPG'
Naoki Hamaguchi talks about pushing past franchise limits
How Final Fantasy 7 Revelation Is Going All Out For The Big Finale: Having Less Content Was 'Never Part Of The Conversation'
Final Fantasy 7 Revelation isn’t backing down from the smorgasbord open-world design of Rebirth, and its developers feel confident in the vision built for the finale to the trilogy
'Final Fantasy VII Revelation' Game Director Interview
Square Enix game director Naoki Hamaguchi talks about the expansive world of the Final Fantasy 7 Revelation, character risks and TV show potential
Final Fantasy VII Revelation Director Explains Why the Physical Disc Version Requires a Download to Play
Final Fantasy VII Revelation director Naoki Hamaguchi has offered an explanation for why the physical disc version of the game on PlayStation 5 and Xbox requires a download to play.
Preview: Playing Final Fantasy VII: Revelation On PS5 Has Me Worried For The Switch 2 Port
Took something perfect and painted it Red XIII
Nintendo’s latest Switch 2 update adds VRR support in TV mode
The new firmware update also includes nostalgic Mii themes
Capcom Announces Mega Man: Dual Override amiibo, Here's A First Look
Arriving the "same day" as the new game
Enbridge to Buy Tallgrass Crude Pipeline Business for $2.55 Billion
Enbridge is expanding its U.S. crude pipeline network with a major Rockies-to-Cushing acquisition.
Mr. T calls his new Netflix documentary 'garbage'
A new Netflix documentary, which premiered Tuesday, tells the story of Mr. T, the celebrity bodyguard turned Hollywood actor. But the "Rocky III" star is not happy about his portrayal: 'That documentary pissed me off.'
Seahawks news: Seattle adds a safety with Nick Emmanwori questionable
The Seattle Seahawks aren’t taking any chances with their safety depth hours before kicking off the 2026 NFL season. With Nick Emmanwori officially questionable for Wednesday night’s Super Bowl rematch against the New England Patriots , Seattle signed safety A.J. Finley from the practice squad to the active roster and elevated Rodney Thomas II, […] The post Seahawks news: Seattle adds a safety with Nick Emmanwori questionable appeared first on ClutchPoints.
Why didn't the Seahawks keep Kenneth Walker III?
The Seahawks spent big to keep their core together -- but that didn't include the reigning Super Bowl MVP.
Smithsonian head retiring amid Trump pressure
Lonnie Bunch III has led the institution since 2019
Artemis II astronaut Victor Glover steps back from NASA, joins Cal Poly
Glover will work closely will Cal Poly's president to position the university as a "global leader in polytechnic education, research innovation and workforce production."
Unfinished business: Women’s soccer sets sights on national championship
After a runner-up finish in the 2025 NCAA Division III national championship, the Eagles return, debuting an all-new back line and familiar offensive firepower, hoping to go one step further this season.
New report highlights six major mental health concerns for students
Orlando nonprofit Breaking Thru unveiled a report detailing six major mental health concerns facing local students this year.
Hemp THC businesses brace for ban in November, drinks get one month of relief
Hemp companies across Missouri and the nation are rethinking their business plans in anticipation of the federal ban.
Dutch scientists pipe office urine into bacteria-filled cells that generate electricity and recover nitrogen and phosphorus, while a related system can produce hydrogen
Pee breaks are one of the most relaxing times in the office when you finally get to have some sane moments to yourself. Which is why most employees take numerous such breaks within a day.
Mark Wahlberg’s ‘By Any Means’ turns 2025 Atlanta into 1966 Mississippi
The civil rights-era film “By Any Means,” which stars Yahya Abdul-Mateen II and Mark Wahlberg, turned 2025 Atlanta into 1966 Mississippi.
OM System PEN review: Get the F out! This camera isn't a PEN-F II – but it's better in every single way
The OM System PEN is the ultimate everyday carry – and in many ways, a better Lumix L10 than the actual L10
Multiple amiibo Listings Have Apparently Been Spotted On GameStop's Internal Database
New Zelda amiibo were announced yesterday
First Real Canon EOS R8 Mark II Images Surface Alongside Full Specs & Pricing
Authentic photos of the Canon EOS R8 Mark II have leaked online, giving a first real look at its controversial angular design, rear joystick, and full specs.
Hawaiian Telcom Unveils Future-Ready Business Fiber Platform Engineered for 10 Gig Connectivity
Hawaiian Telcom announced enhancements to its business fiber internet portfolio, including expanded symmetrical upload and download speeds across Fioptics Business Internet plans and the introduction of Fioptics Advanced WiFi for business customers. Together, these enhancements provide Hawaiʻi businesses with faster, more scalable connectivity backed by a fiber network engineered to support connectivity solutions up to 10 Gig.
Hurricane Lowell forces bank closures across Kauai, parts of Oahu and Maui
All major Hawaii banks closed Kauai branches Tuesday as Hurricane Lowell brought high winds, heavy rain and widespread power outages to the islands.
Washington’s Deuce Davis Continues Havoc at EDGE
Sunday afternoon saw the first reps that Russell "Deuce" Davis II has taken since his three-sack performance in the UCLA game of 2024. That year, he played just 34 defensive snaps before injuries sidelined him for all of 2025. In the Apple Cup, Davis recorded a sack on his first play back. He appeared on …
AI’s Role in Health Care: What Keeps You Up at Night?
At the close of every The Buisness of Health episode, Charles N. Kahn III asks his guests the same question: ‘What keeps you up at night?’ In this highlights episode, Kahn shares intriguing responses on...
National Park Service’s WWII series highlights Washington State nature reserve
Olympic National Park had strategic 13 Aircraft Warning Service stations.
Sporting KC Weekly Schedule: Sept. 8-13, 2026
Sporting Kansas City II News: The official source for all SKC II news, photos, videos, highlights, and more.
Post-World War II economy spurs small-business growth.
This week’s TALE sought out a guest author, Richard “Dick” Coyle, to share the history of one of our long-standing businesses in an article titled “C & C Oil Company: A brief history of 60 years in business.” C & C Oil Company began in 1938 as a simple one-pump service station in Bluffton, Indiana.
Sega's President Says There's Been an Increase in Fans Who Don't Play Its Games, But That Doesn't Mean They Aren't Gamers
Sega president and COO Shuji Utsumi says the company has experienced an uptick in fans who don’t actually play the games it develops and publishes.
After RFK visit, board members seek new policy to keep politics out of schools
Board members look to update rules about what level of politicking should be allowed in schools.
Meet Rachel Chen, the 18-year-old Los Angeles student who expanded a 1997 quantum-math idea to describe entire particle systems with simple diagrams; she won $100,000
At just 18, Rachel Chen has taken a decades-old mathematical idea and expanded it into a visual framework for understanding complex quantum systems, earning her a $100,000 award in the 2026 Regeneron Science Talent Search.
Detroit’s iconic Hotel Yorba has a new owner whose plans are still in flux
The new owner said he had originally planned on an affordable housing conversion but has gone "back to the drawing board" after a meeting with nearby residents.
Mississippi teen overcomes health challenges to harvest 12-foot alligator
Teen credits hunting for keeping her active through rare illnesses
In 2018, scientists seeded clouds over China's Muz Taw Glacier to make snow; the brighter surface was followed by 14% to 17% less ice loss in a preliminary experiment
Researchers in China have tried to make artificial snow over China’s Muz Taw Glacier to slow its melting. The experiment conducted in 2018 involved seeding clouds with silver iodide, which helped trigger snowfall over the glacier.
AMP Sports Launches The Dark Side Podcast with Seattle Seahawks Super Bowl Champions Derick Hall and Byron Murphy II
SEATTLE – September 8, 2026 –Sinclair’s AMP Sports today announced the launch of The Dark Side, a new podcast featuring Seattle Seahawks Super Bowl champions Derick Hall and Byron Murphy II, alongside KOMO News Sports Director Niko Tamurian. Each week, The Dark Side will go beyond traditional game analysis, with Hall and Murphy offering a...
Smithsonian head Lonnie Bunch to retire amid Trump administration effort to reshape institution
Lonnie Bunch III said Tuesday that he will retire as the head of the Smithsonian Institution, a role that placed him at the center of President Donald Trump’s efforts to reshape the world’s largest museum organization.
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
UC Berkeley Law event targets Trump science policies as ‘censorship’
The University of California, Berkeley School of Law organized an Aug. 25 discussion focused on resisting censorship and protecting academic freedom in scientific research.
HOMETOWN HEALTH: Doctors warn of overlooked sports concussion risks as fall season begins
Some symptoms are harder to identify.
HOMETOWN HEALTH: Doctors warn of overlooked sports concussion risks as fall season begins
Some symptoms are harder to identify.
Evaluating Warriors' Biggest Roster Weakness Ahead of Training Camp
The wings will get most of the attention when camp opens in Hawaii, but the real problem for Golden State is in the middle of the floor.
Hawaii County panel approves $90M Keaau Health Center
A Hawaii County panel has cleared the way for Hilo Benioff Medical Center to build an outpatient medical clinic in Keaau.
Scientists found two bat species never known to science in Cameroon’s rainforest after studying bats that looked almost identical
Deep inside the rainforests of southeastern Cameroon, scientists have identified two bat species that had never been formally recognised by science. The discoveries came from surveys in and around Lobéké National Park and the Dja Biosphere Reserve, where researchers examined a small collection of forest bats belonging to the genus Glauconycteris.
Canon EOS R8 Mark II Leak: Specs, IBIS Upgrades, and Design Revealed Ahead of Launch
Leaked Canon EOS R8 Mark II details reveal a redesigned angular body, 7.5-stop IBIS, joystick, and €1,879 price point ahead of its September 15 release.