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Glyphosate: A story of science, risk, and nuance
In the summer of 2014, a California groundskeeper named Dewayne Johnson started noticing patches of raw, weeping skin spreading across his body. He had spent years applying Roundup, Monsanto’s glyphosate-based herbicide, for a school district, sometimes drenched in it when equipment malfunctioned. By 2014, he had a diagnosis: non-Hodgkin’s lymphoma. In 2018, a jury awarded him $289 million in damages, later reduced on appeal. Tens of thousands of lawsuits followed. The story hasn’t quieted down. It’s all over the internet, swinging between “this will kill you, buy organic” and “relax, you’re fear-mongering.” Some of that recent chatter stems from an Executive Order protecting glyphosate and its production, which set off intense infighting within the MAHA movement. Some of it reflects a deeper truth: Americans genuinely care about harmful chemicals in their environment (see poll below). And the conversation isn’t going anywhere, with a Supreme Court case involving Monsanto set for this April. Glyphosate (the active ingredient in Roundup) is one of the most widely used herbicides in the world. But does glyphosate cause cancer? And how much exposure is actually risky? With so much mistrust in institutions and corporations (and some genuine conflicts of interest), making sense of the actual scientific evidence is genuinely hard. Here is a translation of what the scientific evidence actually says. Does glyphosate cause harm? Glyphosate is an herbicide that kills most plants it contacts rather than targeting specific species. It works by blocking an enzyme pathway (EPSPS) that plants and many microorganisms need to produce essential amino acids. Without those amino acids, the plant can’t grow and dies. Glyphosate was first developed by Monsanto in the 1970s and became ubiquitous after the company introduced “Roundup Ready” crops in the 1990s. In 2024, Bayer removed glyphosate from residential Roundup-branded products due to litigation pressure. But today it is still the most widely used herbicide in the world. Farmers also discovered they could spray it directly on crops like oats, lentils, beans, and peas just before harvest to dry them out faster and make harvesting easier. Because of its widespread use, it’s obviously really important to understand if it’s harmful to humans. The key principle: The dose makes the poison The most important concept in toxicology is that “the dose makes the poison.” Sixteenth-century physician Paracelsus articulated what remains the foundational principle of toxicology: sola dosis facit venenum. Water will kill you if you drink enough of it. Aspirin saves lives at 81 milligrams and causes internal bleeding at higher chronic doses. So, at what dose is glyphosate poisonous? The LD50 in rats (the dose that kills half the test animals) is around 5,600 mg/kg body weight. Table salt is roughly 3,000 mg/kg. By that classic measure, glyphosate is less acutely toxic than salt. But some people are exposed to a lot of glyphosate through their work. And among the general public, there are many questions about low-dose, cumulative exposure from multiple sources over long periods. Does glyphosate cause health problems? Cancer Correlation maps are striking, with one analysis finding that 60% of counties that spray the most glyphosate have non-Hodgkin’s lymphoma rates above the national average. But correlation alone doesn’t establish cause, which is why animal and human studies matter. In animals: Rat studies are typically what most fear is rooted in, but most people don’t know the study details on the dosage given to rats. A pooled analysis of the 13 most rigorous rat studies found evidence that very high doses, around 55,000 times greater than typical food residue exposure, can cause certain cancers. In humans: One of the strongest studies followed 55,000 herbicide users over 20 years and found no overall increased cancer risk. There was one signal: among those with the highest use, rates of acute myeloid leukemia (AML) appeared elevated. A broader meta-analysis of 18 human studies also found no overall cancer risk, though a separate meta-analysis focused specifically on non-Hodgkin lymphoma found that people with high cumulative glyphosate exposure faced a 41% higher relative risk compared to those with low or no exposure. These human studies are observational studies (randomized controlled trials would be unethical), and meta-analyses are only as reliable as the studies they pool. But the story seems consistent: at very high exposure levels, there may be some cancer risk. But that’s about as far as the science currently takes us. Emerging research: gut and reproductive health Gut: Because glyphosate targets a pathway that exists in some gut bacteria, scientists have questioned whether it could affect the microbiome. In mice, a 2023 University of Iowa study found that glyphosate altered gut bacterial composition and raised markers of intestinal inflammation. A 2024 systematic review found similar patterns: disrupted gut bacteria and problems with the mucus layer that protects the intestinal wall in mice. Whether this translates to humans is an open question. The human gut is highly variable and resistant, and we don't yet have strong studies confirming the same effects in people. Reproductive health: Animal studies have found that glyphosate-based herbicides can interfere with reproductive hormones, including disrupting egg cell development in mice and reducing the number of eggs available in sheep’s ovaries. However, the doses used in these experiments were high, so it’s not yet clear whether the same effects would occur in humans. On the human side, a 2021 pilot study led by Mount Sinai researchers tested urine samples from pregnant women across the U.S. and found glyphosate in 95% of them. The study also found a possible connection between higher glyphosate exposure during pregnancy and a subtle physical difference measured in female newborns. That said, some connections weren’t statistically reliable and this was a small study. The researchers themselves said more and larger studies are needed before drawing firm conclusions. What do regulators say about glyphosate safety? In 2015, the International Agency for Research on Cancer (IARC), part of the World Health Organization, classified glyphosate as "probably carcinogenic to humans" (Group 2A). The classification is worth taking seriously. But, there’s an important distinction: IARC classifies hazard, meaning the potential to cause harm under some conditions. It does not assess risk, which accounts for actual exposure levels and the real-world probability of harm. The U.S. EPA, the European Food Safety Authority, Health Canada, and regulatory agencies in Australia and Japan have all concluded that glyphosate is “unlikely to be carcinogenic to humans” at realistic exposure levels. They’re asking a different question: given how much of this people actually encounter, what is the probability of harm? Your actual exposure is what determines your actual risk. What does glyphosate mean for your daily life? At the grocery store: Food residues are small. The EPA’s acceptable daily intake is 1.75 mg/kg of body weight per day. To hit that threshold from oatmeal alone, a 150-pound adult would need to eat roughly 50 pounds of oats every day. But this calculation addresses only one pathway (food), and we don’t yet have robust tools to measure people’s actual total exposure. If reducing exposure matters to you, organic certification prohibits synthetic herbicides, and organic oat products generally test at lower or undetectable levels. Either way, a diet rich in whole grains, conventional or organic, is far better for your health than one that omits them out of fear of residues. On the farm: Occupational exposure is orders of magnitude higher than consumer exposure. Farmers and farm workers who mix, load, and apply glyphosate-based herbicides, especially without protective equipment, face meaningfully different risk profiles. Proper PPE isn’t optional. Integrated weed management strategies that rotate chemical modes of action are also worth taking seriously, both for health and for long-term effectiveness. If you live near a farm: Spray drift is real. Concentrations near field edges can spike during and after application, particularly on windy days. This is an area where I think public health could really step up and empower rural communities with buffer zones, rather than placing the onus on individuals. But for now, knowing your local agricultural calendar and keeping windows closed during application are the first steps. Bottom line Dewayne Johnson was exposed to glyphosate at levels most people will never encounter, and a jury decided he deserved compensation. That outcome is not evidence that the oatmeal in your pantry is dangerous. But it is a reminder that the dose, the context, and the person doing the exposing all matter enormously. Glyphosate is a chemical tool with benefits, trade-offs, and genuine open scientific questions. Learning to hold that complexity without collapsing into panic or dismissal is, honestly, one of the most useful and hardest things to do in navigating modern health science. Love, YLE Your Local Epidemiologist (YLE) is founded and operated by Dr. Katelyn Jetelina, MPH PhD—an epidemiologist, wife, and mom of two little girls. Hannah Totte, MPH, is an epidemiologist and YLE Community Manager. YLE reaches more than 425,000 people in over 132 countries with one goal: “Translate” the ever-evolving public health science so that people will be well-equipped to make evidence-based decisions. This newsletter is free to everyone, thanks to the generous support of fellow YLE community members. To support the effort, subscribe or upgrade below: Subscribe
Bioresorbable microneedles track organ health
Nature Reviews Bioengineering - An article in Nature Biomedical Engineering reports a bioresorbable flexible microneedle sensor array for continuous monitoring of organ function for at least 7...
Marathon has sold 1.2M copies across Steam, PS5, and Xbox
Alinea Analytics estimates show that Marathon has generated gross revenues of $55M via 1.2M copies sold on Steam, PS5, and Xbox: Looking at the split between Steam, PS5, and Xbox, Steam is clearly the main platform for Marathon, accounting for a little under 70% of the audience (800K copies sold). Meanwhile, PS5 takes about 19% (217K) and Xbox (including console, PC, and cloud) accounts for a bit over 11% or 133K. Marathon is technically a first-party Sony title, so seeing the home console struggle to break 20% of the volume is a notable data point for the ongoing platform-agnostic debate. PlayStation Studios online games will almost certainly continue being multiplatform (despite Sony reportedly pulling back on PC releases). Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe As for Marathon, the consensus among hardcore players who pushed through the awkward onboarding phase – myself included – is that it’s fantastic. The gunplay, aesthetic, and presentation are among the best in the shooter genre. A great game doesn’t always equal an immediate hit, though, as shown by our estimates. Things are looking lukewarm right now. But this might be one of those marathon-not-a-sprint situations. Had to, didn’t I? Why wasn’t Marathon a hit on the same level as Arc Raiders? One topic that came up in a lot of conversations at GDC this year was why Marathon hasn’t hit the same stratosphere as Arc Raiders. On paper, they’re both extraction shooters, and Marathon has the Bungie pedigree – the house that built the gold standard for gunplay in Halo and Destiny. Marathon’s neon-futuristic aesthetic also distinguishes itself from the gritty realism of Tarkov or the post-apocalyptic hope of ARC Raiders. But vibes can only get you so far for first impressions if the onboarding feels like a brick wall. Marathon is a sweaty PvP-focused experience with a first-time user experience and UI that I can only describe as dreadful. Players are dropped into a complex ecosystem where the UI, though visually striking, is functionally uninformative, forcing users to manually hover over nondescript, identical icons just to identify basic gear or weapon mods. This lack of clarity is compounded by punishing mechanics like a severe heat gauge for movement and a scarcity of vital resources, all without a clear tutorial or a low-stakes mode to learn the ropes. Most people – even top streamers and veteran shooter players – have no idea what’s going on in Marathon at first. Arc is on the complete other end of the spectrum. As we covered here and here, Arc Raiders offers a more collaborative, approachable loop where players often work together toward shared goals. And the objectives are instantly clear. To many players, this contrast only emphasised Marathon’s issues, especially during the testing period. Players understand the Arc Raiders loop within 30 minutes, while Marathon acts as a massive filter, chewing up newcomers and spitting them out before they can experience the depth of Bungie’s signature gunplay. What I’m getting at here is that the poor first-time user experience of Marathon’s Server Slam likely stifled launch sales, while the opposite was true for Arc. Let’s look at the pre-launch copies sold for each game during their respective Server Slams (launch-aligned) : Looking at the trajectory: Arc Raiders saw a massive 80% jump in copies sold during its three-day Server Slam (day -13 to -11). Players jumped in, realised the water was fine, and immediately opened their wallets. Marathon, meanwhile, saw a 49% increase in the four days following its Slam (Day -7 to -3). At the time of each game’s respective launch, Arc Raiders had nearly double the Steam footprint of Marathon – and word of mouth only continued to grow. Bungie could have had more time to fix the onboarding process had the beta happened earlier. But Marathon launched three days after the beta finished. These factors limited the launch sales quite a bit, I reckon. Marathon has found a niche audience, though Despite the friction-heavy start, the data suggests that those who survived Marathon’s onboarding are loving life. We’ve been tracking cross-platform DAUs, and while there’s the expected post-launch leakage, many players are sticking with it. After peaking at 478K total DAUs on its first Saturday, Marathon has settled into a respectable rhythm, holding 345K DAUs as of yesterday and averaging 380K DAUs across the weekend. Steam continues to do the heavy lifting here, consistently accounting for the lion’s share of the daily players. Players have been putting in the hours, too: On Steam, Marathon’s average playtime has climbed to 27.8 hours, significantly outpacing the console averages on PS5 (16.5h) and Xbox (17.3h). Even more telling than the averages: 22% of the Steam audience has surged past the 50-hour mark, and nearly 7% have already logged over 100 hours. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe This data suggests that once the Bungie magic clicks, it hooks players deeper than the average extraction shooter. There’s also started to be a shift in the game’s discourse. Marathon launched as one of those games that’s cool to hate. But as Marathon’s 100-hour club grows, we’re seeing conversations around its mechanical merit outweigh the negativity. Several high-profile creators, who were initially vocal critics, have spent the last week coming around on the mechanical depth of the endgame. It’s a subtle but positive signal; the hate train is losing steam, and a new narrative about the game is emerging. Bungie faithfuls unite Another interesting metric in Marathon’s first few weeks is who, exactly, is playing. Bungie leans heavily on its prestige as the “makers of Halo and Destiny,” in its marketing, and that message has clearly hit the mark. On Steam, the gravity (hammer) of Bungie’s previous work is unavoidable. A staggering 78.2% of Marathon players also played Destiny 2. The trend carries across other platforms, with 74.2% of PS5 players and 82.7% of Xbox players also having played Destiny 2. The Halo legacy lives on, it seems. More on that in a bit. While Destiny 2 went free to play, these numbers still represent a high-intent migration of a fanbase that trusts Bungie’s specific brand of kinetic gunplay and cryptic world-building. The Xbox data adds another layer of legacy. About 85.7% of Marathon players on Xbox have played Halo Infinite, while over half of the Steam audience has spent time in Halo Infinite and 36.1% in the Master Chief Collection (a paid collection of the old Bungie-made legacy games). Interestingly, we see a 55.9% overlap with ARC Raiders on Steam. Overlap is even higher there on PlayStation (60.5%) and Xbox (66.5%). And there’s also significant crossover with Helldivers 2 on all platforms, too. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe Bungie has found some of its fans with Marathon, and the challenge now is keeping this engaged in a high-stakes PvP environment when they’ve spent the last decade primarily enjoying the power fantasies of PvE. On that note… Go the full 26 miles? Or cut and run? Time for some could’ve, should’ve, would’ve. These things would have improved Marathon’s performance at launch: A more robust onboarding process, perhaps in the form of a short single-player/PvE campaign. We know Bungie fans love this stuff. A traditional arena-based mode akin to Destiny’s Crucible could have been a bridge for the cautious players who’d have been otherwise deterred by the Server Slam. It’s also a great palate cleanser after getting merked. Introducing a dedicated PvE environment would have similarly diversified the conversation and lowered the barrier for the Bungie faithful who found the pure PvP extraction loop too abrasive. PvE is safer than PvP these days. There’s an argument that a thin PvE mode would have just felt like a budget Destiny, potentially hurting the brand more. But given how dire the FTUE is, I think it would have been a net positive. Any kind of tutorialised loop that demystifies the stakes, really. While there is merit in a studio sticking firmly to a singular creative vision, and going all in on the hardcore extraction loop. Less forgiving is the technical reality is that the user interface and first-time user experience (FTUE) were not at a commercial standard for launch. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe In a landscape where player time is oversaturated and the most contested currency, a flawed FTUE is a critical failure point. But it’s not all doom and gloom, as Marathon has an incredible, unique gameplay loop, suggesting that financial success is still attainable if Bungie can pivot effectively. Bungie and PlayStation now face a difficult strategic crossroads, though – one within a challenging games market. They could: Double down on Marathon with a long-term Rainbow Six Siege- or No Man’s Sky-style recovery plan, which is something I heard Last Stand Media’s Chris Maldonado mention last week. While this could be a sunk-cost fallacy in action, it could eventually yield the audience the game’s mechanical depth deserves. Shift focus toward the inevitable Destiny 3 or another project, mitigating the escalating opportunity cost and cutting their losses, so to speak. Doing both is an expensive proposition, given the high overhead and burn rate of operating out of Bellevue, Washington. With Sony recently demonstrating a lower threshold for underperforming studios and projects, the margin for error has vanished. Whatever happens, the next six months will determine whether Marathon becomes a cornerstone of Sony’s live-service portfolio or a cautionary tale of vision exceeding accessibility. I’m hoping it’s the former, because Marathon rocks. As always, hit subscribe to get updates on Marathon and other relevant games. Subscribe Want to get your hands on our data for yourself – for free? We’re offering a free trial of our platform for games companies. Send us a message here, or reply to this email, and we’ll set you up. The last word Reply to this email – or reach out here – if you have any feedback for the newsletter – or want to request a game for us to cover. [Alinea Analytics boasts the most accurate PC and console estimates in the business. Game makers use our platform to understand their audience, keep an eye on the competition, monitor sales trends, and spot new opportunities. We equip game studios and financial institutions with accurate data and the confidence to make smarter, data-driven decisions. Want to talk about all things games market data? We’d love to chat!]
Why REI treats CX as a critical business function
The outdoor retailer is focused on doubling down on its differentiators, REI’s Clay Walton-House said. That means investing in its elevated services and member experience.
Scientists say NAD+ could slow aging and fight Alzheimer’s and Parkinson’s
A global team of leading scientists is zeroing in on a tiny but powerful molecule that could reshape how we age. Known as NAD⁺, it plays a crucial role in keeping our cells energized, repairing DNA, and maintaining overall health—but its levels steadily decline over time, potentially fueling diseases like Alzheimer’s and Parkinson’s. Researchers are now exploring ways to boost NAD⁺ using compounds like NR and NMN, with early studies hinting at improvements in memory, metabolism, and physical function.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Microsoft Promises Slew of Windows 11 Changes in Response to "Microslop" Criticisms
With every Windows 11 update seemingly introducing a new bug or somehow breaking some core functionality, it seems as though trust in Microsoft and Windows is at an all-time low, with the recent "Microslop" insult popping up in online tech circles as a sort of culmination of the recent spate of issu...
One arrested, another cited in shoplifting incident at business on East Avenue in Chico
CHICO, Calif. - A Paradise man was arrested and a Forbestown woman was cited by Chico Police in connection to a shoplifting incident at a business in Chico.The Chico Police Department says that at around 12:30 p.m. on Wednesday, March 18, a loss prevention employee observed two suspects stealing several items from a retail business on the 700 block of East Avenue in Chico.Upon exiting the building, the two suspects, a man and a woman, were contacted by the loss prevention employee regarding the stolen items. The employee was able to persuade both suspects to return to the store and hand over the items they had stolen.Authorities say the business expressed their desire to press charges against the suspects and contacted Chico Police to report the crime.Officers reviewed video surveillance that confirmed the employee's account of what happened. Officers then made arraignment for both suspects to turn themselves in the following day.When the suspects, identified as 51-year-old Jamie Leal of Forbestown and 62-year-old Melvin Royal of Paradise, arrived the next day to turn themselves in, authorities say both admitted to their involvement in the incident and elected to write handwritten apology letters to the business.Leal was cited by Chico Police on a misdemeanor charge of shoplifting.Royal was taken into custody and transported to the Butte County Jail, where he was booked on the following charges:Shoplifting with 2+ priors (felony)Shoplifting (misdemeanor) googletag.cmd.push(function() { googletag.display('ad-1514992'); });
Downtown Chico business owner voices concerns over street closures for events
A DOWNTOWN CHICO MERCHANT IS EXPRESSING CONCERN OVER THE IMPACT OF STREET CLOSURES FOR EVENTS -- ON THEIR BUSINESS. ACTION NEWS NOW REPORTER BELLA BARBOSA REPORTS FROM DOWNTOWN CHICO { "@context": "https://schema.org", "@type": "VideoObject", "name": "Downtown Road Closure Dilemma", "description": "A DOWNTOWN CHICO MERCHANT IS EXPRESSING CONCERN OVER THE IMPACT OF STREET CLOSURES FOR EVENTS -- ON THEIR BUSINESS. ACTION NEWS NOW REPORTER BELLA BARBOSA REPORTS FROM DOWNTOWN CHICO", "thumbnailUrl": "https://bloximages.newyork1.vip.townnews.com/actionnewsnow.com/content/tncms/assets/v3/editorial/c/47/c47e26d6-03c3-5f35-bf49-37925ab603d7/69bdedc4eb57d.image.jpg", "uploadDate": "2026-03-20T17:45:00-07:00", "contentUrl": "https://cdn.field59.com/KHSL/1774053903-6e1ef36dd09fbebf020833aee86b60da3b3cca3f_fl9-720p.mp4" } CHICO, Calif. - A downtown Chico business owner is voicing concerns about the impact of street closures for events on local shops. Leann Powell, owner of The Peddler’s Closet, expressed concern about events closing down streets downtown and bringing in food trucks and other shops’ products that directly compete with the brick-and-mortar stores in downtown Chico.Powell said an upcoming event held on a Saturday has brought up concerns for her and other business owners downtown, due to it being a busy day for businesses. "We're already struggling, and then to bring in more businesses on top of our businesses and shut our streets down is absolutely devastating," said Powell.Powell noted a decline in business during events like the Thursday Night Market, where street closures allow outside vendors to set up shop. She shared that while organizers for these types of events often offer booths to local businesses, it does not alleviate the burden."I don't really feel like that's a solution because you're bringing in other businesses, you're shutting the streets down. Yes, we can go down and set up a space, but then you've gotta pay somebody to run that space, plus run your own business for the day, and it's really not, it's really not helpful for us," said Powell.Applying for a street closure permit in Chico involves approval from the Public Works Department, the Chief of Police, and the Fire Chief. Permits can be denied only under a handful of circumstances, such as interference with first responders, previously scheduled construction, or existing permits for the same space.Mayor Kasey Reynolds addressed the issue, saying the city council has tasked staff with reviewing the municipal code for street closure permits with the goal of finding ways to minimize negative impacts on local businesses during events.Reynolds mentioned that any recommended changes might require further direction from the city council, depending on the extent of any changes recommended. googletag.cmd.push(function() { googletag.display('ad-1514992'); });
Men are losing a key chromosome with age and it may be deadly
Aging men often lose the Y chromosome in a growing number of their cells—and it may be far more dangerous than once believed. This loss has been linked to heart disease, cancer, Alzheimer’s, and shorter lifespans. Researchers suspect Y-less cells may grow faster and disrupt normal body functions. What seemed like a minor genetic quirk could actually be a major driver of age-related disease.
Treasury Department to take over some federal student loans, as Trump administration works to dismantle Education Department
The Treasury Department will begin to manage federal student loans in default, taking on a key function of the Education Department as the Trump administration further pushes to dismantle it.
Providence May Sell Off Health Insurance Business
The Providence Health Plan was already outsourcing some of its core functions, but had previously denied it had plans to sell.
Providence May Sell Off Health Insurance Business
The Providence Health Plan was already outsourcing some of its core functions, but had previously denied it had plans to sell.
By studying muscle function, student aims to improve others’ physical health—and maybe his own | Harvard T.H. Chan School of Public Health
Sam Lapp, PhD ’26, delves deep into the biology of how muscles work.
The best strength training plan might be simpler than you think
New strength training guidelines emphasize that doing any resistance training is what truly matters. Based on decades of research, experts say even simple routines can increase muscle, strength, and physical function. The key is not perfection but consistency. In fact, the best workout plan is the one you can maintain long term.
German Health Minister Nina Warken and WHO Hub in Berlin highlight 2025 achievements
Germany’s Federal Minister of Health, Nina Warken, visited the WHO Hub for Pandemic and Epidemic Intelligence in Berlin today to review progress and launch its 2025 Annual Report. The report highlights advances in using artificial intelligence, data science and pathogen genomics to strengthen global preparedness for future pandemics.In 2025, the WHO Hub in Berlin worked with more than 160 Member States and over 190 partners to help countries and organizations develop new systems and tools to detect and understand new public health threats as quickly as possible, whenever and wherever they occur.BMG to confirm whether they wish to contribute a quote. “Detecting outbreaks early is one of the most effective ways to save lives and prevent epidemics from becoming global crises,” said Federal Minister of Health Nina Warken. “Germany is proud to host and support the WHO Hub for Pandemic and Epidemic Intelligence. Its work strengthens our safety at home and helps protect people worldwide.”Artificial intelligence is increasingly transforming the detection of outbreaks. In 2025, the Hub launched an upgraded version of the Epidemic Intelligence from Open Sources (EIOS) system, which uses enhanced AI functions to scan global online information in real time and help experts quickly identify unusual health events. The system is now used by 120 countries.To better anticipate health threats, countries need information beyond traditional health data. The Hub supports countries in implementing Collaborative Surveillance, which integrates data on climate, animals, travel, and population movement to provide a more comprehensive and real-time understanding of health threats.The Hub also expanded global access to pathogen genomics, which helps scientists detect new pathogens, such as viruses and bacteria, understand how they spread and how dangerous they may become. Through the International Pathogen Surveillance Network (IPSN), the WHO Hub in Berlin worked with 309 partners in 101 countries to expand access to these technologies.“We are in a new era of global health threats, and we need new tools to face tomorrow’s challenges,” said Dr Chikwe Ihekweazu, Executive Director of the WHO Health Emergencies Programme. “The WHO Hub in Berlin helps countries use data and technology more effectively so they can identify risks earlier and respond faster. No country can address these threats alone. Strong cooperation remains our best defence.”“Berlin offers an ideal environment for our work. We collaborate closely with world-leading institutions such as the Robert Koch Institute and the Charité Center for Global Health,” said Dr Oliver Morgan, Head of the WHO Hub for Pandemic and Epidemic Intelligence. “Germany has supported the WHO Hub since its establishment, and we are pleased to welcome Federal Minister Nina Warken to the Hub today. This strong partnership helps us advance innovation in pandemic and epidemic intelligence and better support countries to prepare for future health threats.”The Hub is expanding the use of advanced analytics and mathematical modelling to forecast how outbreaks may develop and to assess which response measures are most effective. Through its Collaboratory, the Hub connects modelers and analysts with governments to ensure their work addresses real public health needs. In 2025, the community grew to 1300 members from 50 countries and 200 institutions. An AI-powered pandemic simulator, currently in the prototyping phase, will help decision-makers compare outbreak scenarios and help identify effective disease control measures.
8 new stores, entertainment venues coming to Woodfield Mall
Lindt Swiss Master Chocolatiers has led a wave of eight new stores and entertainment venues coming to Woodfield Mall in Schaumburg this spring. Lindt is already open on the upper level Grand Court nea...
Is this the world’s first quantum battery? Australian scientists say so
Researchers say their prototype is a big step towards fully functioning batteries with rapid charging times
Thymic health and immunotherapy outcomes in patients with cancer
Nature - A deep-learning approach applied to routine CT scans is used to quantify the health of the thymus in a cohort of patients with cancer, and shows that thymic function is associated with...
810 Entertainment brings bowling, dining, gaming to The Arboretum of South Barrington
A new entertainment venue offering an all-in-one destination for dining, games and private events is now open at The Arboretum of South Barrington. Village representatives, community leaders and memb...
Philip Morris International U.S. to Launch New Business Solutions Center, Creating 180 Jobs in Tampa Bay Area
Today, Philip Morris International's U.S. businesses ("PMI U.S.") announced an investment of approximately $50 million in a new Business Solutions Center in Tampa, Florida. The Center will create approximately 180 direct and indirect high-skilled jobs and represents a pivotal expansion of PMI U.S. operations, consolidating key functions—business solutions, distribution operations, and customer service—into a single hub. This investment is designed to enhance operational efficiency across these f
Scientists Reveal the Simplest Rule for Building Strength
New resistance-training guidelines show that any amount of strength training can significantly improve muscle, strength, and physical function.
Strengthening One Health Field Epidemiology Capacity in the WHO South-East Asia Region
Recent public health emergencies—including the COVID-19 pandemic, recurrent zoonotic disease outbreaks, and the high level of antimicrobial resistance—have underscored the urgent need for strong, multisectoral field epidemiology capacities. This reinforces the importance of a workforce equipped with One Health field epidemiology competencies. To address this need, WHO works with the Food and Agriculture Organization of the United Nations (FAO), the United Nations Environment Programme (UNEP), and the World Organisation for Animal Health (WOAH), as part of Quadripartite Alliance for One Health, to strengthen field epidemiology training programmes using a One Health approach.These efforts are aligned with WHO SEARO’s Strategic Framework for Action for Strengthening Surveillance, Risk Assessment and Field Epidemiology and the Regional Roadmap to Advance Field Epidemiology Capacities 2025–2029 emphasize workforce development, multisectoral collaboration, and enhanced preparedness for health emergencies. With funding from the Pandemic Fund, The Competency for One Health Field Epidemiology (COHFE) integration within Field Epidemiology Training Programmes (FETPs) or similar initiatives has been initiated in Bangladesh and India and is planned in Sri Lanka.BangladeshIn Bangladesh, COHFE is being adapted to strengthen the Field Epidemiology Training Programme, Bangladesh (FETP-B) Advanced programme. Initiated in July 2025 and led by the Institute of Epidemiology, Disease Control and Research (IEDCR), the process brought together stakeholders from human, animal, and environmental health sectors, academia, and laboratories.A Multisectoral Working Group (MWG) was established to guide implementation, conduct readiness assessments, and identify opportunities to institutionalize One Health collaboration. Through national multisectoral consultations and a competency prioritization workshop held in Dhaka in November 2025, stakeholders identified priority technical competencies for surveillance, outbreak investigation, data analysis, and risk assessment, alongside functional competencies related to leadership, coordination, and the laboratory–epidemiology interface. The process also surfaced systemic barriers—such as challenges in data sharing and limited joint investigations—enabling targeted recommendations. These outcomes are guiding curriculum revision, the introduction of One Health simulations and joint field exercises, and the development of a national multisectoral mentorship pool, with updated training materials expected to be implemented in the upcoming cohort.Figure 1. Competency prioritization involving multisectoral stakeholders“COHFE represents a significant step forward in operationalizing the One Health approach. The collaboration between national institutions and the Quadripartite partners is critical for building resilient systems to address complex health challenges in the region.”, Prof. (Dr) Tahmina Sirin, Director, Institute of Epidemiology, Disease Control and Research (IEDCR), Bangladesh.Aligning India’s One Health Training with COHFEIn India, the National Centre for Disease Control (NCDC) has strengthened One Health workforce development through its SectorConnect initiative. WHO supported a comprehensive competency mapping and curriculum review to align the Field Epidemiology Programme in One Health (FEP-OH) with all 14 COHFE domains. The review identified strong foundations while generating actionable recommendations to strengthen One Health learning outcomes, expand joint field-based learning, and enhance competency-based assessment. These improvements are informing programme refinement and phased scale-up across additional states.Figure 2. Strengthening learning outcomes for the SectorConnect FEP OH CurriculumThrough these efforts, WHO SEARO will continue to support countries to move from separate sector-based training toward an integrated, impact-driven One Health field epidemiology workforce capable of addressing complex health threats at human-animal-environment interface.ReferencesFood and Agriculture Organization of the United Nations, World Health Organization, & World Organisation for Animal Health. (2024). Competencies for One Health field epidemiology (COHFE) framework. https://www.who.int/publications/i/item/9789240080058World Health Organization. (2023). Strategic framework for action for strengthening surveillance, risk assessment and field epidemiology for health security threats in the WHO South-East Asia Region. WHO Regional Office for South-East Asia. https://www.who.int/publications/i/item/9789290210030World Health Organization. (2024). Regional roadmap to advance field epidemiology capacities in the WHO South-East Asia Region 2025–2029. WHO Regional Office for South-East Asia. https://www.who.int/publications/i/item/9789290229544
Scientists revive activity in frozen mouse brains for the first time
‘Cryosleep’ remains the preserve of science fiction, but researchers are getting closer to restoring brain function after deep freezing
All gas, no brakes for Schaumburg entertainment district development after Andretti Karting opens
While Tuesday’s opening of Andretti Indoor Karting & Games in Schaumburg was an economic development victory itself, it might also hit the accelerator on future phases of the entertainment distr...
Woman Sleeps in Closet for 2 Years While Building Jewelry Business Out of Studio Apartment (Exclusive)
Jessica Holiday shares that she's been living in her closet while building her jewelry business. The 25-year-old tells PEOPLE she used to live in her van before moving into a studio apartment, which also functions as her office.
Figuring out why AIs get flummoxed by some games
When winning depends on intuiting a mathematical function, AIs come up short.
Parallels Desktop creators say MacBook Neo does indeed have enough muscle to run Windows apps
The company’s virtualization software is functional on Apple’s cheapest laptop.
Century Therapeutics Reports Full Year 2025 Financial Results and Business Updates
CNTY-813, lead beta islet cell therapy program as a potential functional cure for type 1 diabetes, in Investigational New Drug (IND)-enabling studies; IND submission expected in 4Q 2026 to support anticipated initial clinical data in 2H 2027CNTY-308, a CD19-targeted CAR-iT cell therapy engineered with Allo-Evasion™ 5.0, on track to enter the clinic in 2026Strengthened balance sheet and cash runway extended into 1Q 2029 from oversubscribed $135 million private placement in January 2026 PHILADELPH
Exercise and brain function, hedgehog hearing, and can AI change our minds?
The Guardian’s science editor, Ian Sample, talks to Madeleine Finlay about three eye-catching science stories from the week
Young Africans score higher than Americans on 'mind health,' new study finds: Wealth ‘not an indicator’ of well-being
A new Sapien Labs study found that young people in Ghana and Nigeria are much more able to function than those in the U.S.
Science Shorts: Rice for weight control, functional dairy tech and more
Rice for weight control, functional dairy tech and more feature in this edition of Science Shorts
Choreographing molecular design with TANGO
Nature Computational Science - A reward function (TANGO) is developed to enforce building blocks in generative artificial intelligence and leverage the synthesizability of high-value materials.
Myomo and Elevance Health Agree to Contract for Multi-State Network Participation
BURLINGTON, Mass., March 09, 2026--Myomo, Inc. (NYSE American: MYO) ("Myomo" or the "Company"), a wearable medical robotics company that offers increased functionality for those suffering from neurological disorders and upper-limb paralysis, announced today it has entered into its first among a series of expected network participation agreements with Elevance Health. The contracts, which include the Anthem-affiliated Commercial, Medicare Advantage, and Medicaid plans are expected to become effec
Erectile dysfunction can signal heart disease in otherwise healthy men
Erectile dysfunction can indicate heart disease years before cardiovascular issues arise. In fact, most heart problems don’t even start in the heart itself.
Samsung Wallet Launches Digital Home Key for Smart Door Locks
Digital Home Key lets Samsung Wallet users unlock their homes within the connected Samsung Galaxy ecosystem Functionality is built on Aliro, the CSA’s open standard for smart locks
Research in college and NFL athletes links early sports specialization to higher injury rates
New research presented at the 2026 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS) studied college and National Football League (NFL) players to determine the long-term impact of early, single-sport specialization on injury risk. The studies showed that repetitive stress from focusing on one sport from a young age can have negative, lasting effects on the musculoskeletal system, potentially making them more prone to hip dysfunction, reduced function, and surgical interventi
Galaxy S26 Ultra’s Horizon Lock Feature Was Tested To Its Limits By Being Taped On A Functioning Drill Machine; The Results Were Downright Impressive
The Horizon Lock feature on the Galaxy S26 Ultra was tested to the extreme as Samsung’s flagship was taped to a powered drill machine
Opinion | The State of Our Union’s Political Dysfunction
We are fighting for the soul of the country, and nobody is going to be the first to stop shouting.
Defying all odds, doctor transforms adopted daughter's health using functional medicine
When a doctor was told there was no cure for his daughter's condition, he was motivated to transform not only her health, but the lives of thousands of others.
Anker’s latest noise-cancelling wireless headphones boast huge battery life and smart functionality
The Soundcore Space 2 feature a massive 70-hour battery life
Scientists just created chocolate honey packed with surprising health perks
Scientists in Brazil have transformed cocoa waste into a functional chocolate-infused honey packed with antioxidants and natural stimulants. Using ultrasound waves, they enhanced honey’s ability to pull beneficial compounds from cocoa shells—no synthetic solvents required. The process is considered green and sustainable, and the product could find its way into gourmet foods and cosmetics.
LCA scoreboard, horn malfunction pauses Pistons/Cavs game
A malfunction at Little Caesars Arena caused the buzzer to go off midway through the 3rd quarter of the Pistons' game against the Cavaliers on Friday.
Scientists compared dinosaurs to mammals for decades but missed this key difference
Baby dinosaurs weren’t coddled like lion cubs or elephant calves—they were more like prehistoric latchkey kids. New research suggests that young dinosaurs quickly struck out on their own, forming kid-only groups and surviving without much parental help, while their massive parents lived entirely different lives. Because juveniles and adults ate different foods, faced different predators, and moved through different parts of the landscape, they may have functioned almost like separate species within the same ecosystem.
The First Couple of a Dysfunctional DHS
A forthcoming book reveals new details about Kristi Noem and Corey Lewandowski.
Out-of-sync offenses collide as Suns host Lakers
Two teams in varying states of offensive dysfunction will meet when the Phoenix Suns host the Los Angeles Lakers on Thursday.
Google details MCP-like ‘AppFunctions’ that let Gemini use Android apps
Following the Gemini automation announcement today, Google is detailing how all this works under the hood on Android.
Samsung is cloning Pixel features for the Galaxy AI suite on S26
The Samsung Galaxy S26 series has gained a few software functions and features being lifted right from Pixel phones
One type of olive oil has a surprising effect on brainpower during aging
New study reveals extra virgin olive oil may protect brain health by improving gut bacteria and cognitive function in older adults.
WHO Eastern Mediterranean Region and Pan American Health Organization sign agreement to strengthen hospital resilience
25 February 2026 (EMRO/PAHO)—WHO’s Regional Office for the Eastern Mediterranean (EMRO) and the Pan American Health Organization (PAHO) have signed a Memorandum of Arrangement to strengthen collaboration on making hospitals safer and better prepared for health emergencies and disasters. At a time of growing instability and constrained resources, this collaboration positions hospitals as a dependable anchor for communities, ensuring they remain open, functional, and capable of delivering life-saving care when it matters most.
Windows 11 KB5077241 update improves BitLocker, adds Sysmon tool
Microsoft has released the KB5077241 optional cumulative update for Windows 11, which comes with 29 changes, including improvements to BitLocker, a new network speed test tool, and native System Monitor (Sysmon) functionality.
Science & Medicine: Exercise is medicine for people with Parkinson's disease
Exercise can improve function and slow disease progression in people with Parkinson's disease, but why? A UT Health San Antonio researcher is studying patients who exercise and play virtual reality games to see if she can figure out the answer.
War Department Announces Realignment of Anomalous Health Incidents Cro
The War Department recently announced the realignment of the Anomalous Health Incidents Cross‑Functional Team to the Office of the Undersecretary of War for Research and Engineering.
Migrants are not responsible for the UK’s healthcare crisis
They are not a burden on the NHS, but a vital part of how it functions.
Daniel Miller
Daniel Miller is a reporter at POLITICO covering the intersection of entertainment, media, sports, technology and politics.Part of POLITICO’s California team since 2026, he examines how Hollywood and Southern California function as engines of political power. Daniel also covers the rainmakers, dealmakers and cultural figures who shape policy debates, elections and public life far beyond the state’s borders.Daniel previously spent 13 years at the Los Angeles Times, most recently as an enterprise reporter in the newspaper’s Metro department, where he worked on investigations and features. He wrote about allegations of sexual misconduct at L.A.’s Magic Castle, chronicled the cratering ventures of a celebrity vegan chef and detailed themystery of a missing million-dollar pocket watch once owned by J.P. Morgan. In 2019, he wrote, reported and hosted "Larger Than Life," an award-winning podcast about the life of an enigmatic L.A. street racer.He previously covered the business of entertainment for The Times, examining the fraught political ties between the Walt Disney Co. and the city of Anaheim, probing the world of second-tier talent agents operating on Hollywood’s fringes and uncovering allegations involving several #MeToo figures.Daniel was named Journalist of the Year at the 2015 National Arts & Entertainment Journalism Awards and, a year later, received the L.A. Press Club’s Entertainment Journalist of the Year award. He was also a finalist for the 2016 Loeb Awards for "Selling Stardom," a series on unscrupulous Hollywood operators. His narrative reporting has been honored by organizations including the Society for Features Journalism, the National Association of Black Journalists and the Motor Press Guild.Daniel began his career reporting in Southern California, writing for the Ventura County Star, the Los Angeles Business Journal and the Hollywood Reporter. He attended Beverly Hills High School and UCLA. He lives in Los Angeles.
Vanderbilt Health remembers C. Leon Partain, former chair of Radiology
Clarence Leon Partain, MD, PhD, professor emeritus of Radiology and Radiological Sciences, whose work in nuclear medicine and magnetic resonance imaging helped shape the field of academic radiology, died Jan. 28 in Brentwood, Tennessee. He was 85. After beginning his career as a nuclear engineer at Oak Ridge National Laboratory and as faculty at the University of Missouri and the University of North Carolina, Dr. Partain joined the ranks at Vanderbilt Radiology in 1980 and was promoted to professor in 1984. He later became the first Carol D. and Henry P. Pendergrass Professor of Radiology and Radiological Sciences and chair of the department (1992-2000), and subsequently the director of the Center for Imaging Research. Shortly after arriving in Nashville, Dr. Partain began to lead Vanderbilt Radiology’s nuclear medicine division. He remained in this role until he was named the department chair. Dr. Partain specialized in multiple fields, including nuclear medicine, magnetic resonance imaging and positron emission tomography. Following his time as chair, Dr. Partain shifted his focus to research and spent time working clinically with radiology’s chest imaging section. In 2015, he retired and was honored for his years of service and named as emeritus faculty. Dr. Partain also held an appointment as professor of Biomedical Engineering. A Tennessee native, Dr. Partain was born in Memphis and later graduated from high school in Clarksville. He then received his BS in nuclear engineering from the University of Tennessee, his MS and PhD in nuclear engineering from Purdue University and his MD from Washington University. He completed his residency training in diagnostic radiology and nuclear medicine at the University of North Carolina. Dr. Partain was clinically trained and certified in diagnostic radiology and nuclear radiology by the American Board of Radiology (ABR) and the American Board of Nuclear Medicine. Throughout his career, Dr. Partain contributed to the growth of Vanderbilt Radiology and received many academic and research accolades across the specialty through various associations. During his time leading the department, clinical studies increased from 180,000 to 260,000 cases per year, emerging technological imaging equipment expanded the department’s capabilities, and units for angiography and fluoroscopy were added to the tool kit. The department also expanded its footprint with outpatient imaging in Nashville, Bedford County and more. Research continued to expand with continued growth in scientific findings and millions in grant funding for radiopharmaceuticals, functional MRI, nuclear medicine, X-ray, ultrasound and more. Dr. Partain is celebrated for being instrumental in bringing the first MRI and PET/CT machines to the Medical Center. His efforts helped build Vanderbilt Radiology’s prestige in the world of academics and research both nationally and internationally. His society affiliations included the American College of Radiology, the American College of Nuclear Medicine, and the International Society of Magnetic Resonance in Medicine (ISMRM). He served as president of the Radiological Research Alliance of the Association of Academic Radiologists and has held executive roles as a member of many radiological society boards. Dr. Partain was editor-in-chief of the Journal of Magnetic Resonance Imaging from 2000 to 2013 and a member of the editorial boards of Magnetic Resonance in Medicine, Magnetic Resonance Imaging, the American Journal of Roentgenology, Academic Radiology, the Journal of Nuclear Medicine and Investigative Radiology. He has authored/co-authored/edited six textbooks, including one of the first comprehensive textbooks on MRI, “Nuclear Magnetic Resonance (NMR) Imaging.” Dr. Partain has also authored/co-authored/edited approximately 100-plus book chapters and 200-plus journal articles. In 2000, Dr. Partain received the Distinguished Service Award from the ABR. In 2014, he received the Distinguished Service Award from the ISMRM. In 2016, he received the Alumni Achievement Award from Washington University for his “contributions to advance the fields of nuclear medicine and medical imaging.” Dr. Partain served the ABR as an examiner for 20 years, the Accreditation Council for Graduate Medical Education as a member of the Nuclear Medicine Residency Review Committee, and Vanderbilt University School of Medicine in multiple capacities. A devout Baptist deacon and man of committed faith, he is survived by his wife of 62 years, Judy; children, David (Rebecca), Teri (Bland), and Amy; brother, Larry (Deb); brother-in-law, Tom (Cathy); grandchildren, Sarah (Brandon), Amy, Luke, Tucker, Alex, Ryan and Jake; cousins and a host of nieces and nephews. Vanderbilt Health is grateful to Dr. Partain for his decades of service and major contributions to clinical and research imaging.
Local sports schedule for upcoming week
It looks like Mother Nature might be cruel to the local sports teams in one of the most important weeks yet in the winter sports season. So far in the winter sports season, there have been warm temper...
RWJBarnabas Health Names Odette Perriel Senior Vice President of Support Services
RWJBarnabas Health, the largest, most comprehensive academic health care system in New Jersey, has appointed Odette Perriel, MS, as Senior Vice President, Support Services. In this role, Ms. Perriel will oversee support services functions across RWJBarnabas Health facilities for Food & Nutrition, Environmental Services, and Patient Transportation.
After thousands of years, scientists discover a new function of yawning
In a new study, yawning has been shown to push the brain’s clear fluid in the opposite direction of a deep breath.
Mountain Studies Institute’s new executive director bridges science and policy
There’s no better way to learn about a river than being upside down inside it, says Molly McKeon, a Durango resident and the new executive director of the Mountain Studies Institute. At a time Southwe...
Axis Health cuts three Durango staff members
Three staff members were laid off this week from Axis Health System’s Durango Integrated Healthcare clinic as part of a broader restructuring effort that eliminated a total of 13 positions across 11 c...
Science & Medicine: An over-the-counter supplement could boost the results of exercise in older adults
A study of two groups of 70-year-olds found that branched-chain amino acids combined with exercise improve physical function and quality of life. Exercise alone did not.
Book review: ‘Capitol Crude’ details decades of oil industry impact on Alaska politics
The new book by Lisa Weissler will thrill policy wonks and inform those seeking a clear-eyed understanding of how Alaska reached its present dysfunction.
Apple’s Latest Attempt to Launch the New Siri Runs Into Snags
Apple Inc.’s long-planned upgrade to the Siri virtual assistant has run into snags during testing in recent weeks, potentially pushing back the release of several highly anticipated functions.
2025 US ACT on Health Equity Community Investments Recipients
Author: Kennesha VanBurch, Director, Health Equity and Community Investment Partnerships 2025 marks the fifth year of the US Accelerate Change Together (ACT) on Health Equity: Community Solutions Challenge (CSC) and National Strategic Collaborations (NSC). This year, we received more than 250 applications from organizations across the country dedicated to prioritizing the social, cultural and linguistic needs of communities that have experienced barriers to care and opportunity. The overwhelming response underscores the vital role these organizations play in advancing health equity at the local level and across the nation. Since the launch of ACT on Health Equity in 2021, the initiative has invested more than $18 million in nonprofit organizations and their health equity programming through CSC and NSC. This year, $3.4 million in funding has been provided to 47 nonprofit organizations that focus on healthcare access, nutrition and lung health. Together, we are making meaningful progress toward health equity across the US. Supporting Organizations Advancing Community Well-being and Health Equity The awarded organizations address critical needs across health, education, and social support through initiatives aligned with AstraZeneca’s areas of expertise, including lung disease, lung and breast cancer, and cardiology. Their work spans across culturally competent senior care, equitable healthcare access, cancer and chronic disease support, and preventive health education, as well as hunger relief, community gardening, dental and transportation services, and resources for underserved families. Together, they are working to remove barriers to care, reduce preventable conditions, and empower individuals and communities of all ages and backgrounds to achieve better health outcomes. Photo courtesy of Medical Motor Service of Rochester and Monroe County, Inc. Description: MMS driver speaking to a Wegmans shopper. GGWNY staff; Lincoln Memorial Church Community Garden and lead gardener Diane Learn more about our recipients and the impact they make within their communities below. Community Solutions Challenge Advocates for Women’s Health, Inc. Advocates for Women's Health exists to provide access to high quality prenatal care and gynecology care to lower-income communities in and around Fresno, CA. They operate a nonprofit OB/GYN clinic located in Fresno. American Rescue Workers (ARW) ARW is a faith-based, non-profit organization providing homelessness and hunger prevention services in Central PA since 1934. ARW cares holistically for men, women, and children who find themselves facing food insecurity, and emergency situations that may lead to homelessness, or an actual homeless crisis, by providing shelter and social services. ARW serves people no matter their faith, regardless of faith. Asian Americans Advancing Justice Southern California (AJSOCAL) AJSOCAL is a social justice organization that protects and strengthens the rights and dignity of AAPI communities, especially those that are most disadvantaged. Byrd Cancer Education and Advocacy (BCEA) BCEA’s mission is to effectively assist individuals battling cancer by connecting them to vital support and resources. BCEA ensures that all relevant information reaches those in need, guiding them towards the resources necessary to fight their battle against cancer. Catholic Charities of the Diocese of Santa Rosa Catholic Charities of the Diocese of Santa Rosa creates access to opportunities for self-sufficiency by providing innovative and compassionate services to people of all backgrounds, beliefs and cultures. Chosen Hearts Chosen Hearts’ mission is to rebuild lives and restore hope by fostering a sense of community and creating lasting, positive change. Columbia Student Medical Outreach The Columbia Student Medical Outreach Program (CoSMO) Clinic is the oldest and largest student-run free clinic at the Vagelos College of Physicians and Surgeons at Columbia University. At its core, CoSMO is guided by the belief that all people—regardless of immigration or insurance status—deserve access to high-quality, equitable medical care. Eagle’s Nest Community Kitchen and Resource Center and Mobile Pantry Eagle’s Nest Community Kitchen, Resource Center and Mobile Pantry’s mission is to empower underserved and rural communities through hands-on STEM education grounded in sustainable agriculture. By combining mobile workshops, community gardens, and mentorship, they deliver accessible training in science, technology, engineering, and math that builds practical skills, advances food security, and fosters environmental stewardship. Through collaborative partnerships and by honoring local knowledge, they cultivate resilient communities and inspire the next generation of agricultural innovators. eClose Institute eClose Institute’s mission is to make medically relevant scientific discoveries using an education platform that embraces equality and empowers participants to contribute ideas, life experience and experimental data to improve disease treatment. Equal Hope Equal Hope is an organization dedicated to saving lives and improving quality of life by eliminating health inequities. This organization challenges the status quo in striving to understand the context of people’s lives and the barriers they experience to help them achieve better health outcomes for their lives. Through research, quality assessment and improvements, advocacy, education, and patient navigation, they approach health holistically to achieve sustainable outcomes and true health equity. Food For Free Committee Food For Free improves access to healthy food through establishing innovative programming and partnerships to overcome barriers and strengthen the community food system. They believe that access to healthy food is a fundamental right. Grassroots Gardens of Western New York (GGRWNY) The missions of GGRWNY is to share knowledge, powers, and resources to grow health food, heal systemic harm, and strengthen neighborhood connections through community gardens. Greater Providence YMCA (GPYMCA) GPYMCA builds healthy spirit, mind, and body for all, through inclusive programs and relationships grounded in core values of caring, honesty, respect, and responsibility. Programs are intentionally designed to close equity gaps in health, education, and wellness. GPYMCA serves individuals and families across all life stages and income levels, including medically vulnerable and underserved populations. Hearts of Valor INC Hearts of Valor’s missions it to keep the heart pumping through advocacy, collaboration, education, and support. Ibn Sina Foundation Ibn Sina Foundation ensures the health of the community by providing integrated, preventive, and primary care in a clinical setting through the dissemination and application of health-related knowledge, thereby enhancing the quality of life for future generations. India Home India Home is a non-profit organization dedicated to addressing the needs of and empowering the South Asian and Indo-Caribbean senior immigrant community in New York City through culturally competent services. At India Home’s centers, seniors find community and resources through a diverse range of programs and activities. Programs include congregate meals, creative aging programs, case management programs, and educational talks on health, nutrition, financial safeguards and elder law. La Colaborativa La Colaborativa empowers the Latinx community, enhancing social and economic health, and holding institutional decision-makers accountable. Lancaster County Food Hub At the heart of the Lancaster County Food Hub’s (LCFH) work is a strong commitment to meeting basic human needs, fostering respectful relationships, and connecting neighbors with supportive services in a nurturing and welcoming environment. Guided by their vision of a Lancaster County where every individual is supported and empowered to live with dignity and stability, they strive to not only provide immediate relief but also to create pathways to lasting self-sufficiency. Maryland Foundation of Dentistry (MFD) MFD is dedicated to improving oral health outcomes and preserving dental function for one of the state’s most vulnerable populations: adults with intellectual, physical, and/or developmental disabilities who are unable to afford the cost of dental care. Maternity Care Coalition (MCC) The missions of MCC is to improve the health and well-being of pregnant women and parenting families and enhance school readiness for children 0-3. MCC achieves this through direct service, advocacy, and research, in collaboration with individuals, families, providers, and communities. Medical Motor Service of Rochester and Monroe County, Inc. Medical Motor Service of Rochester and Monroe County’s mission is to provide specialized transportation for community organizations, as well as individuals with disabilities and special needs to improve their independence and quality of life. Milwaukee Consortium for Hmong Health (MCHH) MCHH’s mission is to create a thriving and healthy Southeast Asian and Hispanic community by empowering families through education and screenings. MCHH utilizes established community health workers and focuses on addressing health disparities related to cancer and chronic disease among the Hmong, Bumese, Karen, Karenni, Lao, and Hispanic populations living in Milwaukee, WI and other areas if needed. Mission Hospice and Home Care Mission Hospice and Home Care is delivering compassionate support and exceptional care in the home for individuals and communities, guiding them with choice and dignity to navigate significant care decisions. North Alabama AHEC (NAAHEC) The mission of the NAAHEC is to improve healthcare access, quality, and equity in rural and underserved communities across North Alabama. They strengthen the health workforce - particularly through the development of community health workers by providing comprehensive training, resources, and advocacy. By fostering strong community partnerships and promoting healthcare literacy, NAAHEC aims to address disparities, improve outcomes, and cultivate a healthier future for North Alabama. Our Neighbors’ Table Hunger comes in many forms. Our Neighbors’ Table is committed to establishing a community that provides for the whole person with nourishing food, kindness and dignity. Panhandle Breast Health Panhandle Breast Health works to decrease breast cancer deaths by providing education and reducing financial barriers to increase screening rates. Pitney Meadows Community Farm Founded in 2026, Pitney Meadows Community Farm’s mission is to celebrate and explore agricultural education, healthy food production, and recreation. Located on 166 acres in the heart of the city of Saratoga Springs and preserved in perpetuity as a working farm, Pitney Meadows is a unique resource. Prince William County Community Foundation (PWCCF) PWCCF’s mission is to create a stronger, healthier, and more connected community by addressing critical needs in food insecurity, health & wellness, scholarship, and philanthropy. PWCCF is committed to empowering individuals and families through equitable access to nutritious food, comprehensive healthcare, educational opportunities, and community-driven support. By fostering partnerships and promoting sustainable solutions, PWCCF aims to enhance the quality of life for all, ensuring a brighter future for every member of their community. Raytown Christian Church (Raytown Summer Lunch Ministry) Raytown Summer Lunch Ministry’s mission is to provide nutritious and kid-friendly meals to children during the summer months when they are not in school and receiving school meals. Regents of the University of California, Davis UC Davis Health is improving lives and transforming health care by providing excellent patient care, conducting groundbreaking research, fostering innovative, interprofessional education, and creating dynamic, productive partnerships with the community. RSVP Volunteers RSVP Volunteers creates and runs unique community programs powered by skilled volunteers to advance education and wellness for all ages and strengthen nonprofits through capacity-building and volunteer services. Second Harvest Food Bank of Orange County Second Harvest Food Bank of Orange County, in collaboration with partners, provides dignified, equitable and consistent access to nutritious food, creating a foundation for community health. The Icla da Silva Foundation The mission of the Icla da Silva Foundation is to save the lives of patients whose only cure is a bone marrow transplant by providing financial, emotional, and logistical support to remove barriers to treatment. There With Care of the Bay Area Founded in 2012, the mission of There With Care of the Bay Area is to provide a wide range of meaningful and fundamental services to children and families during the critical phase of a medical crisis. Universal Community Health Center Universal Community Health Center’s mission is to provide quality and accessible healthcare to under-served communities and to provide a patient centered model of care to empower communities towards wellness. West Cancer Foundation West Cancer Foundation breaks through barriers to cancer care and improves patient outcomes by providing accessible patient resources, early detection and education, and community-based research. Westside Family Healthcare Westside Family Healthcare’s mission is to improve the health of communities by providing equal access to quality healthcare, regardless of ability to pay. National Strategic Collaborations Foundation of Asthma and Allergy Impact Rescue (AAIR) The mission of The Foundation for Asthma and Allergy Impact and Rescue (AAIR) is to make sure that every child is rescued at school, healthy at home, and connected to care. Family Reach Foundation Family Reach is a nonprofit that provides non-medical financial support to families facing cancer. Cancer treatment requires more than medicine — families need a roof over their heads and food on their tables to survive. If a family can’t meet these basic needs, cancer treatment takes a back seat. They work with patients, providers, and community organizations to challenge the systems that force families to choose between their health and their home. LUNGevity Foundation LUNGevity Foundation is transforming what it means to be diagnosed and live with lung cancer through research, advocacy, and community. This mission brings them closer to their vision: a world where no one dies of lung cancer. Association of Black Cardiologists The Association of Black Cardiologists is dedicated to preventing and treating cardiovascular disease, including stroke, through education, research, advocacy, and community engagement, striving for optimal health for all by eliminating disparities. Cholangiocarcinoma Foundation (CCF) The Cholangiocarcinoma Foundation’s (CCF) mission is to find a cure and improve the quality of life for those affected by cholangiocarcinoma (bile duct cancer). Founded in 2006, in Salt Lake City, UT, by a family who lost a loved one to cholangiocarcinoma, CCF has grown to become the leading global resource in research, education, and public awareness. ZERO Prostate Cancer Zero Prostate Cancer’s mission is to improve and save lives from prostate cancer through advocacy, awareness, education, and support. GO2 for Lung Cancer GO2 for Lung Cancer relentlessly confronts lung cancer on every front, every day, for everyone. As the nation’s leading lung cancer advocacy organization that was founded by patients and survivors, they are dedicated to increasing survival and quality of life for those at risk, diagnosed, and living with lung cancer. National Minority Quality Forum The National Minority Quality Forum (NMQF) is a national 501(c)(3) with a mission to reduce patient risk for all. Young Survival Coalition (Breast) Young Survival Coalition supports the young breast cancer community and ignites global collaboration to improve quality of life worldwide. Black Women’s Health Imperative Black Women’s Health Imperative’s mission is to solve the most critical health issues that Black women and girls face through innovative programs, transformative research, and lifesaving policies.
Local sports schedule for upcoming week
Although it seems like winter never came to Durango, local winter sports will be over sooner, rather than later. Durango High School’s boys and girls basketball teams will celebrate their seniors on ...
New Lehigh Valley appliance business to hold grand opening with raffles, refreshments and more
Individuals seeking to enhance their home’s functionality with state-of-the-art appliances for cooking, laundry and other household tasks have a new showroom to browse in Lehigh County.
Move 2.0 adds Audio Tracks with clip warping, live processing; more - CDM Create Digital Music
If you’ve got an Ableton Move, you can take advantage of its public beta today, too, just by connecting Move to your computer. And this is a huge release: in addition to other new functionality, Audio Tracks support warping clips and live-processing audio. This has the power to turn Move into a serious pint-sized powerhouse, […]
Trump Administration to Cut $600 Million in Health Funding From Four States
The states, all led by Democrats, used the grants to support a wide variety of functions, including H.I.V. prevention and surveillance.
Firearm injury survivors face long-term health challenges
Survivors of firearm injuries often experience long-term physical and functional health challenges that extend beyond the initial trauma, according to Rutgers Health researchers. Their recent study has ...
Scientists may have found the brain network behind Parkinson’s
A new international study points to a specific brain network as the core driver of Parkinson’s disease. Scientists found that this network becomes overly connected, disrupting not just movement but also thinking and other bodily functions. When researchers targeted it with non-invasive brain stimulation, patients showed much stronger symptom improvement than with conventional stimulation. The discovery could reshape how Parkinson’s is diagnosed and treated.
Entertainment for everyone
Several performers, marking notable album anniversaries this year, lead the entertainment highlights set for local and regional entertainment over the next two weeks. Rock band Tommy James and The Sho...
Regional science fair explores musical chickens, AI, cybertrucks and cereal brands
The 68th annual San Juan Basin Regional Science Fair brought together more than 80 students from over a dozen schools Wednesday at Fort Lewis College. Students shared their findings from a range of un...
Microsoft rolls out native Sysmon monitoring in Windows 11
Microsoft has started rolling out built-in Sysmon functionality to some Windows 11 systems enrolled in the Windows Insider program.
FDA warns that Johnson & Johnson heart pump sensors may malfunction—22 injuries reported
There is a risk of users making adjustments during treatment that are unnecessary. The FDA is still evaluating the issue at this time.
Night owl or early bird: Chronotype can influence your health and muscle strength
Being more active in the morning or afternoon is not just a matter of personal preference. Chronotype, which is each person's biological tendency to function better at certain times of the day, can play ...
Maingear Retro98 Desktops Pack Modern Gaming Hardware in Vintage Beige Designs
Maingear has officially announced its latest retro-themed pre-built desktop PCs, the Retro98. The new pre-built desktops are built in SilverStone FLP02 chassis, replete with a functional turbo button—for setting PWM-controlled fans to max speed—and a big red power toggle switch, and they can be had ...
James Perkins named interim executive director of Auxiliary and Business Services
Perkins ’92 will provide functional oversight to Auxiliary and Business Services, leading the unit’s operations that support and enhance campus life for students, faculty and staff, alumni, and visitors.
What Happens to Your Body When You Take Vitamin D Supplements Every Day Long Term?
A daily vitamin D supplement can support bone strength, muscle function, and balance—especially in people who are vitamin D deficient.
Investment and Statecraft: The International Politics of Sovereign Wealth Funds - Georgetown Journal of International Affairs
In 1953, Kuwait established the world’s first sovereign wealth fund to invest the country’s oil revenues and generate returns that would reduce its reliance on a single resource. Since then, over 100 separate funds have been created to preserve national wealth and ensure long-term fiscal sustainability. Today, they manage over $10 trillion in global assets. In this discussion with GJIA, political economist Kathryn Lavelle explains the increasingly novel dynamics that surround fund behavior and what the world can come to expect from their growing presence in international financial markets. GJIA: When it comes to the roles sovereign wealth funds (SWFs) play in global markets and politics, what would you say makes them unique? Kathryn Lavelle: Sovereign wealth funds (SWFs) operate on behalf of governments as investors. That in itself is a strange relationship. Within them, a core contest takes place between the state’s interests (or sovereign) part of the dynamic, and the money interests (or wealth) part of it, and these two aspects are frequently in contradiction, serving fundamentally different goals. SWFs are also quite fascinating because when you talk to the people who manage these funds, they have an interest in convincing you that the decisions are made almost exclusively on a financial basis—they really will go to great lengths to differentiate their government owners and those who make the management decisions. At the same time, these people ultimately answer to someone in power. Therefore, for most SWFs, it remains deeply unclear who is actually making the investment decisions and for what purposes. Of course, it is not always clear how other vehicles, such as hedge funds and private equity make the decisions they do, but I think what a lot of people find particularly disconcerting about SWFs is that they seem to act on behalf of people who have a different identity from their own. People who could be trying to manipulate politics and markets in a way that would have a long-term effect on their own populations. Regular investors come and go at will, and they only share an interest in profit as far as most of us understand. However, SWFs have that extra “sovereign” part right behind them that obscures their true interest. GJIA: These funds can be found in countries all across the globe, in both authoritarian states and democracies. Would you say SWFs differ in their goals and structures between regime-type? KL: It is not necessarily regime type that makes the goals and structures of SWFs different. It has to do with their economies. Let’s look at a country like China. There’s going to be a debate about exactly how to characterize the regime, but it is a country with many different kinds of sovereign wealth funds, and a particularly opaque state connection to each. At one time, some of the state-owned Chinese oil companies created specialized investment vehicles listed outside Chinese markets that excluded parts of the firms that were more associated with human rights violations. At the same time, the China Investment Corporation (CIC)—China’s largest SWF—draws a lot of concern, not necessarily because of its investment activities, but because of the dynamics of global politics. So, I wouldn’t really tie differences to regime types themselves in a wholesale way, but rather to how such funds are perceived and how they are structured. Saudi Arabia’s SWF is getting all kinds of attention for its involvement in Hollywood, and this takes me right back to when I was a student in the 1980s, when people were concerned about Japanese investment entities buying assets in Hollywood. They aren’t quite the same in financial terms, but it’s the same kind of concern about foreign investment that drives people to be suspicious, and the whole idea that “foreigners are influencing Hollywood.” This holds true across industries, and it reflects where politics are in places like the United States right now. One metric we can try to look at is transparency, where all the funds will tell you, “we are transparent.” The problem you’ll keep running into with this approach is how you value things. When trying to do comparative studies of equity markets, you’ll find that every country doesn’t use Generally Accepted Accounting Principles like we do in the United States. A fund may appear opaque politically and not want people to show what they’re invested in or what their intent with that investment is, but they could also just not be able to report it because of the way it was purchased, or the kinds of shares they purchased. There are some assets out there that really are difficult to put a monetary value on. GJIA: To what extent do domestic politics shape SWF behavior in both the investing “home” country and the recipient “host” country? KL: This depends on the type of fund present and also on the extent to which voters’ political views are able to influence the fund. For example, in a democratic home state like Norway, the SWF doesn’t invest in nuclear weapons or tobacco because of social concerns, but there is a continuing debate over whether it should invest in oil, even though that’s where most of the money comes from. The degree to which Norway will continue to make those investments, and whether they contradict the government’s overall climate goals, is an open question in Norwegian politics. Because of the way the fund’s governance is structured, it may not be easy to resolve. On the other hand, some people consider pension funds, like the State Teachers Retirement System (STRS) in Ohio, to be quasi-SWF. They have a very strict separation between the people who make up the management division and the fund owners. No teacher or professor would want to invest in things that may harm the future of their students. At the same time, a fund manager might see an opportunity in a diversified multinational corporation that offers a good return, despite it deriving part of its revenue from e-cigarettes. These contests are very apparent. Domestic politics can work in host countries too. A good example is Singapore’s SWF, Temasek, investing in Thailand’s telecommunications sector. If you study political economy, you already know that countries everywhere are uncomfortable with foreign ownership of their telecom sectors because a foreign entity could monitor or manipulate our communications with each other. In the case of Temasek, there was significant pushback from Thai citizens surrounding the deal, which went on to influence national political sentiment toward Singapore as a whole, underscoring the risks some SWFs may face with their investment choices. In this case, fund behavior led to the dissolution of the entire Thai government in 2006 and a subsequent coup d’état. GJIA: To address some of this unease, the Santiago Principles were established in 2009 to ostensibly promote trust and transparency. From your perspective, have these mechanisms actually changed fund behavior? KL: In international relations theory, we always like to have a clear set of norms and best practices—the orientation we want the proverbial ship to be going in. In that regard, the Santiago Principles at least got the discussion going about which direction SWFs should take at a time when people were very skittish about the growing size of these funds. Nobody wanted them to be out there and potentially destabilizing economies, so talks about disclosure, conditions for withdrawal, and the independence of managers were helpful when initiated. The biggest stumbling block was that there wasn’t exactly a good way to measure compliance with the Principles, let alone how to hold funds to them. If you read the Principles, they’re overall quite vague. In general, a fund doesn’t want to reveal how and why they make certain investment decisions because that information is proprietary—a fund makes money off of how and why it makes decisions—so how do you reconcile that with loosely-defined ideas of openness? Some decisions might have a political purpose. The bottom line is that trying to figure out and assign a score to compliance is not easy, and it is therefore the reason why the Santiago Principles never really got off the ground to the point where they could truly direct fund behavior. GJIA: Many emerging markets are looking to build their own SWFs from mineral and oil revenues. Historically, have funds shaped development trajectories in these countries? KL: I think the big story in international emerging markets investment is that the investment is increasingly no longer unidirectional. In the past multinational corporations of primarily Western background were the main form of foreign direct investment in a country. That has changed dramatically, to the point where you have companies from so-called “developing countries” taking over companies in the United States. Therefore, the landscape of international investment has changed, and I think SWFs are certainly a possibility to be the next step in the game. Historically, you didn’t need an entire financial vehicle to reinvest commodity revenues in your country, but as emerging markets get more financially sophisticated, their capacity to operate such funds has increased. SWFs would allow treasuries to move from relying on holding foreign exchange assets like cash or government bonds to having broader financial markets and targeted growth areas, while easing pressure on welfare expenditures. GJIA: With their increasing financial weight, do you see the presence of SWFs being a factor in the political choices leaders will have to make with regard to domestic and foreign policy? KL: It will depend on just how big the funds get. One of the reasons people are already apprehensive is because of their scale, and if certain SWFs in certain countries achieve a large-enough size, the presence will absolutely be cause for concern. The other factor political leaders will have to consider are their objectives. It’s not always clear how to define a SWF, or even where its activity is concentrated, but it is certainly a worry from the perspective of national security of opaque external investment. More than that, I think one of the most interesting questions going forward is whether the United States, the home to the world’s largest financial markets, will develop its own fund, for which the Trump administration announced a plan. There have also been several proposals in Congress. Were it to come into being, it would have tremendous weight. At the same time, one of the hallmarks of U.S. capitalism is a lack of government ownership of shares, so it would not be clear how such a fund would be received in domestic politics, or which direction it would take. Given how politically fragmented the country is, a Democratic administration would likely be concerned about different sectors of the economy, such as healthcare, and want investment there, rather than a Republican administration, which might prefer defense industries. No investment vehicle could thrive under conditions of such instability. Moreover, it remains unclear where the money to fund a theoretical U.S. SWF would come from. It would be a fundamentally different entity depending on whether it is financed with debt, economic surplus, commodities, or the sale of state companies, as in the case of Singapore. If it is debt, or government borrowing of some form, then the fund would have to outperform whatever the cost of that debt is, which is not an easy thing to do. I think our political leaders have enough on their plate. Our system has worked well keeping political and investment functions generally separate. We have seen different forms of business rise and fall, and even the perception of different countries, all of which funds are tied to. Unless a major SWF either starts—like in the case of the United States—or collapses—an issue that concerns the Saudis, I don’t see any political tsunamis on the horizon. . . . Kathryn Lavelle is the Ellen and Dixon Long Professor of World Affairs at Case Western Reserve University in Cleveland, Ohio. Her research explores the exchange between domestic and international and political institutions with a particular emphasis on political economy and multilateralism. Dr. Lavelle’s first book, The Politics of Equity Finance in Emerging Markets, explored the political circumstances that surround large issues of stock in the developing world. After being granted tenure at Case Western, she was awarded an American Political Science Association Congressional Fellowship and named the William A. Steiger fellow, a designation given to the most promising political scientist in her class of fellows. While in Washington during 2006-2007, she worked on the staff of the House Committee on Financial Services on issues related to domestic and international monetary policy. Dr. Lavelle holds a PhD in political science from Northwestern University; an M.A. in government and foreign affairs from the University of Virginia; and a bachelor’s degree in international economics from Georgetown University. She is a permanent member of the New York Council on Foreign Relations. This transcript has been lightly edited for clarity and length. Interview conducted by Sid Mehrotra. Image Credit: Jason Leung, Unsplash Content Licenses, via Unsplash
Rebuilding Colorado’s talent pipeline system
By Randy Johnson The rule of thumb in designing and building anything is form follows function — you always build for a clear and specific purpose. This principle holds true for structures, vehicles, applications, seemingly anything, other than many educational systems and government functions. During the next few months, Colorado has a powerful opportunity to […]
10+ Things to Know About the New AirTag 2
After a five year wait, Apple finally unveiled the next-generation version of the AirTag earlier today. The AirTag 2 looks exactly like the original AirTag, and the functionality is similar, but there are still some differences worth knowing about. Here's everything new. UWB 2 - The AirTag 2 adopts Apple's second-generation Ultra Wideband (UWB) chip. Longer Range - UWB upgrades mean that Precision Finding works from 1.5x further away than before.
Scientists say quantum tech has reached its transistor moment
Quantum technology has reached a turning point, echoing the early days of modern computing. Researchers say functional quantum systems now exist, but scaling them into truly powerful machines will require major advances in engineering and manufacturing. By comparing different quantum platforms, the study reveals both impressive progress and steep challenges ahead. History suggests the payoff could be enormous—but not immediate.
This is Android 17’s blur, new screen recorder, & more in leaked screenshots [Gallery]
The Android 17 leaks continue today with a preview at the upcoming blur effect for System UI, as well as functional changes and updates.
Amazon is selling a 2-in-1 laptop and tablet for just $70
Shoppers say "the functionality is great."
Business Notes for Jan. 25, 2026
The Gazette's Business Notes is a compendium of the week's promotions, new hires, certifications, added business lines and business events, among other items, in Cedar Rapids, Iowa City and the rest of the Corridor.
Country leads the entertainment lineup
Jason Aldean leads the entertainment highlights coming to local and regional entertainment over the next couple of weeks. The country singer, set to release his 12th studio album “Songs About Us” in A...
Oswego YMCA to hold comedy night Feb. 27
OSWEGO — The Oswego YMCA invites the community to enjoy an evening of laughter and entertainment at “Live from Oswego, New York — It’s Comedy Night,” taking place Feb. 27 at the Lake Ontario Event and Conference Center.Doors open at 6 p.m. for cocktails, appetizers, auctions, and live music by Joe Cortini and the Jazz Mafia. The comedy show begins at 7 p.m. and is presented by Compass Federal Credit Union. × This page requires Javascript. Javascript is required for you to be able to read premium content. Please enable it in your browser settings. kAm%96 6G6?:?8 H:== 36 9@DE65 3J 6>466 v6@C86 qC@25H6==[ 2 =@?8E:>6 7C:6?5 2?5 DFAA@CE6C @7 E96 ~DH68@ *|rp] qC@25H6== 92D D64C6E=J H2?E65 E@ ECJ DE2?5\FA 4@>65J 7@C J62CD[ 2?5 9@DE:?8 E96 *’D 4@>65J 6G6?E >2C65J] (96E96C 96 DFCG:G6D :E @C ?@E C6>2:?D E@ 36 D66?]k^Am #placement_726068_0_i{width:100%;margin:0 auto;}var rnd = window.rnd || Math.floor(Math.random()*10e6);var pid726068 = window.pid726068 || rnd;var plc726068 = window.plc726068 || 0;var abkw = window.abkw || '';var absrc = 'https://ads.empowerlocal.co/adserve/;ID=181918;size=0x0;setID=726068;type=js;sw='+screen.width+';sh='+screen.height+';spr='+window.devicePixelRatio+';kw='+abkw+';pid='+pid726068+';place='+(plc726068++)+';rnd='+rnd+';click=CLICK_MACRO_PLACEHOLDER';var _absrc = absrc.split("type=js"); absrc = _absrc[0] + 'type=js;referrer=' + encodeURIComponent(document.location.href) + _absrc[1];document.write('');kAm$9@H @A6?6C v=6?? “v@>6K” p52>D :D 2 46?EC2= }6H *@C< C25:@ =686?5 2?5 4@>65:2?[ 3C:?8:?8 564256D @7 6IA6C:6?46 E@ E96 DE286[ D92C:?8 D92CA 4@>65J 2?5 >6>@C23=6 DE@C:6D 7C@> 9:D =:76 2?5 42C66C] p 72>:=:2C 7246 2E $JC24FD6\2C62 4@>65J ?:89ED 2?5 6G6?ED[ p52>D :D 2 ECF6 46?EC2= }6H *@C< @C:8:?2=]k^AmkAmp52>D 92D 366? 2 7:IEFC6 :? =@42= >65:2 D:?46 `hg`] x? E96 DF>>6C @7 `hgb[ 96 9@DE65 E96 @G6C?:89E D9@H @? H92E H2D E96? |28:4 `_c]f[ =2E6C 364@>:?8 4@F?ECJ DE2E:@? q`_c]f] w6 ;@:?65 *hcu| :? `hgc[ H96C6 96 9@DE65 r=F3 v@>6K 2E ?:89E 367@C6 >@G:?8 E@ E96 >@C?:?8 D9@H H:E9 “q:8 |:D ;@:?65 E96 >@C?:?8 D9@H @? r=2DD:4 #@4< %zhh[ H9:49 =2E6C 3642>6 E96 7=28D9:A C25:@ DE2E:@? 7@C $JC24FD6 &?:G6CD:EJ DA@CED]k^AmkAmp52>D 9@DE65 E96 2H2C5\H:??:?8 r@249 y:> q@696:> 42==\:? D9@H 7@C ad J62CD 2?5 4@?E:?F6D E@ 9@DE E96 D9@H H:E9 $JC24FD6 32D2:?D 24E:G6 A6C7@C>:?8 2?5 AC@>@E:?8 4@>65J E9C@F89@FE E96 C68:@?]k^AmkAm%96 6G6?:?8 9625=:?6C[ qC6?52 #6:?92C5E[ H:== 56=:G6C D92CA[ C6=2E23=6 4@>65J C:77:?8 @? 28:?8[ 2 DFCAC:D:?8 s}p E6DE C6G6=2E:@?[ 2?5 DA@E\@? :>A6CD@?2E:@?D] “$>2CE[ D2DDJ[ 2?5 F?7@C86EE23=6[ D96 :D 2 >FDE\D66 :? E96 =:?6FA[” 2? 6G6?E DA@6C E@ DE2?5\FA 4@>65J[ #6:?92C5E 3682? 96C 42C66C 27E6C >6?@A2FD6 2?5 96C D64@?5 5:G@C46[ 3C:?8:?8 2 C67C6D9:?8=J 9@?6DE 2?5 F?4@?G6?E:@?2= A6CDA64E:G6 E@ E96 DE286] w6C 5:G6CD6 =:76 6IA6C:6?46D :?4=F56 H@CFD:4[ 6DA64:2==J 92:C 32?5D 2?5 962GJ >6E2=[ #6:?92C5E DE2CE65 5CF>>:?8 :? 96C d_D 2?5 9@A6D E@ :?4@CA@C2E6 96C >FD:42= E2=6?ED :?E@ 7FEFC6 DE2?5\FA A6C7@C>2?46D]k^AmkAm“p 4@>65J ?:89E 8:G6D FD E96 @AA@CEF?:EJ E@ 46=63C2E6 @FC 4@>>F?:EJ H9:=6 DFAA@CE:?8 2? :>A@CE2?E >:DD:@?[” D2:5 %C:?2 |:==D[ G:46 AC6D:56?E @7 E96 ~DH68@ *|rp 3@2C5 2?5 6G6?E 4@>>:EE66 >6>36C] “(96? A6@A=6 4@>6 E@86E96C E@ =2F89[ E96J’C6 2=D@ 96=A:?8 6?DFC6 E96 *|rp 42? 4@?E:?F6 D6CG:?8 @FC 4@>>F?:EJ E9C@F89 AC@8C2>D E92E AC@>@E6 H6==?6DD[ 4@??64E:@?[ 2?5 @AA@CEF?:EJ]”k^AmkAm!C@4665D 7C@> E96 6G6?E DFAA@CE E96 ~DH68@ *|rpUCDBF@jD >:DD:@? 2?5 AC@8C2>D] vC@FA 2?5 3FD:?6DD E23=6 A24k^2m]k^Am googletag.cmd.push(function() { googletag.display('ad-2978731'); });
What is Hol+? Dr. Taz’s new holistic health hub explained
Learn how Hol+ blends functional, primary and lifestyle medicine to treat stress, hormone imbalance and metabolism for whole‑body wellness.
The Idea of Community Vs. Identity Politics
What began as a means of protecting the marginalized increasingly functioned as a mechanism of separation.
NL elementary students show off their science skills
A select group of Slatington Elementary students have been celebrated for putting their scientific skills to the test. Superintendent Dr. Matthew J. Link said at Monday’s school board meeting that he ...
Rikers manager position moves forward as monitor cites 'dysfunction'
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How John Kennedy, a G.O.P. Senator, Became a Best-Selling Book Author
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Endocrinology — Uniting the Legacy and Future of Basic Endocrine Science
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From Borges to Jennifer Aniston: Science begins to illuminate the mysteries of memory
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Western Pacific Region achieves milestone: 19 countries complete comprehensive health information system assessments
The Health Information and Digital Health (HID) unit in the WHO Regional Office for the Western Pacific has successfully supported 19 countries, covering 99% of the Region’s population, to conduct comprehensive health information system (HIS) assessments, surpassing the regional target of 15 set for 2025 and advancing efforts toward universal health coverage. Using SCORE, a technical package of essential interventions, recommended actions, tool and resources developed by WHO and partners to address challenges in meeting HIS needs, these assessments systematically assess health data availability and quality, enabling countries to monitor trends, identify and respond to emerging health challenges, and improve policies and programmes for healthier families, communities and societies. The first round of SCORE assessments were conducted between 2019-2021 in 14 countries in the Region and over 130 countries globally. The second round of SCORE assessments were conducted between 2024-2025.SCORE assessments are a key priority identified by Member States and WHO at all levels, including within WHO-Country/Multi-Country Cooperation Strategies, the Regional Vision Weaving Health for Families, Communities and Societies in the Western Pacific Region (2025–2029), and the WHO Fourteenth General Programme of Work (GPW 14, 2025–2028). Within the Regional Vision, implementing SCORE assessments is a key action for technology and innovation to advance health equity (strand 5).The SCORE for Health Data technical package is based on five key interventions, represented by the acronym SCORE. Interventions S, C and O focus on strengthening core data sources. Survey (S) covers population-based health surveys, surveillance systems and censuses, including their capacity to monitor health-related SDGs. Count (C) focuses on birth, death and cause of death registration as parts of a functional CRVS system. Optimize (O) addresses routine health service data and key health service inputs such as health financing and health workforce.Interventions R and E focus on data use for action. Review (R) examines regular analytical reviews of health sector progress and performance, together with national analytical capacity. Enable (E) looks at the policy, governance, and digital foundations needed to support effective data use.The Western Pacific Region shows relatively strong performance in the Review (R) and Count (C) interventions. Most countries in the Region demonstrate good analytical reporting and institutional capacity for analysis and learning. More than two-thirds of countries show more mature CRVS systems, driven by improvements in birth and death registration. However, medical certification of cause-of-death remains a key gap, with limited or low coverage in over half of countries in the Region.Performance under the Survey (S) intervention is mixed. While surveillance systems are generally strong, several countries in the Region continue to face challenges in implementing their surveys and censuses. Monitoring health-related SDGs is still a challenge for more than a third of countries in the Region.The greatest challenges are observed in the Optimize (O) and Enable (E) interventions. More than half of countries have lower maturity levels in routine health service and resource systems. Two-thirds of countries also face challenges with effective use of data and evidence for policy and action, largely due to gaps in digital infrastructure, governance and legislation for health data systems, and especially in data and sharing. &amp;amp;amp;amp;amp;nbsp;As part of the SCORE methodology, multi-stakeholder consultations and validation workshops were conducted in many countries to review findings and plan strategies for HIS strengthening. The HID unit continues to provide targeted support to facilitate dialogue and assist countries in developing HIS improvement plans. These plans guide governments and partners to align investments and coordinate efforts for maximum impact.WHO also assists countries with tailored technical support to address key gaps as requested by countries/national health authorities. SCORE assessments should be conducted periodically to monitor progress in HIS strengthening, although progress across addressing gaps identified in SCORE should be continually tracked as countries implement improvements.Additional countries will be supported to implement SCORE in 2026. The Regional Vision delivery-for-impact target, endorsed by Member States, is for all countries and areas to have implemented SCORE assessments and have an increased SCORE index by 2029 while WHO is aiming for 80% of Member States in the Region to conduct round two assessments. Countries yet to complete assessments are therefore encouraged to contact the HID unit at the WHO Regional Office for the Western Pacific for tailored support.The implementation of SCORE HIS assessments in the Western Pacific Region was supported by The Gates Family Foundation.
11-game stretch serves as proof that Warriors' offense finally is starting to function as designed
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Ikea Smartened Up Some of Its Artsy-Fartsy Lights
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WellSpan Health Announces Comprehensive Migration of Technology Portfolio to AWS
Add to FavoritesWellSpan Health, the leading health care system serving Central Pennsylvania and Northern Maryland, today announced plans for a comprehensive cloud migration of its full technology infrastructure. Together with Amazon Web Services (AWS) as its preferred cloud provider, WellSpan will transition its applications, data and environments from traditional data centers to AWS. This migration will establish the foundation for delivering next-generation, AI-enabled health care solutions that reduce administrative burden and improve outcomes for patients across the region and beyond. Supercharging Innovation, Efficiency and Patient Outcomes WellSpan's migration of systems and clinical applications, which serve 1.2 million patients across nine hospitals and 250+ facilities, is expected to be complete by April 2026, one of the fastest full-scale migrations in the health care industry. This transformation enables WellSpan to unify disparate data systems for care teams and patients alike, achieving operational efficiencies and care improvements that fragmented systems are unable to deliver. “Our comprehensive migration to the cloud accelerates our ability to deploy new clinical capabilities that transform patient care while advancing our overall innovation strategy,” said Roxanna Gapstur, Ph.D., R.N., president and CEO, WellSpan Health. “When a physician can access complete patient imaging in seconds instead of hours, we're not just modernizing technology—we're improving patient outcomes. Our new cloud infrastructure also enables us to quickly implement solutions that will free our clinicians from thousands of hours of administrative work annually so they can focus on what they do best: caring for our communities.” The transition allows WellSpan to move away from a data center-based model and enables the rapid deployment and scale of AI technology. WellSpan’s strategic partner, General Catalyst’s Health Assurance Transformation Company (HATCo), facilitated the collaboration with AWS to support the migration. WellSpan’s transformation journey benefits from HATCo’s specialized technology solutions, as well as General Catalyst and AWS’s significant partnership to improve patient outcomes, which was announced in January 2025. “Our decision to go all-in on AWS will enable insights and innovations impossible in traditional siloed environments,” said Kasey Paulus, executive vice president and chief operating officer, WellSpan Health. “This is the largest health care technology transformation in our region's history, and it positions WellSpan to be a premier partner for technology leaders across the country.” “WellSpan is building a foundation with AWS that will improve care and outcomes for patients across their health system by bringing data together into standardized formats that are optimized for AI applications,” said Dan Sheeran, vice president and general manager, Healthcare and Life Science, AWS. “To do this, it is essential to have the most secure and compliant cloud when handling patient data, along with AWS’s built-in AI governance and responsible AI frameworks that follow the industry’s highest standards to protect patient information. We look forward to continuing to work alongside WellSpan as they unlock the cloud and AI’s full potential to deliver exceptional care to their patients.” Key Benefits of the AWS Collaboration Full Portfolio Migration: WellSpan will transition its applications and data from on-premises data centers to AWS, including full IT environments and specialized applications for functions such as nursing, cardiology, pharmacy and the company’s supply chain systems. This represents approximately 7.5 petabytes of clinical and non-clinical data and more than 300 applications—the most comprehensive health system cloud migration in the Mid-Atlantic region. Approved Architectures: AWS will deliver secure, WellSpan-specific architectures tailored to each build, ensuring compliance and reliability across the health system. Unified, AI-Ready Data: Migrating to AWS enables WellSpan to harmonize data across separate systems, transforming unstructured clinical notes and multi-modal datasets into standardized, AI-ready formats. Accelerated Results and Improved Outcomes: Automated data normalization and processing will enable the deployment of applications that reduce turnaround times for items such as analyzing medical imaging or patient records from days to minutes, helping clinicians get patient results faster and improving overall health outcomes. Reduced Administrative Burden: The transition to AWS will enable swift deployment of AI-powered solutions that reclaim thousands of hours for WellSpan’s clinical and corporate teams, allowing them to focus on patient care rather than paperwork. Elastic Infrastructure: Cloud architecture will enable WellSpan to scale computing resources dynamically, supporting seasonal demand fluctuations without infrastructure investments, as well as the rapid deployment of new services across multiple locations simultaneously. Most Secure, Compliant Cloud: AWS offers the highest network availability of any cloud provider, with more than 166 HIPAA-eligible services and certifications for global compliance standards, including HITRUST CSF. Built-in AI governance and responsible AI frameworks ensure that WellSpan’s data is protected under the industry’s most rigorous standards. Tags:News releaseInnovation and partnerships