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Democrats relish big fundraising gains for Senate races favoring Republicans
While Democrats touted their totals, they offer only a snapshot of overall fundraising, as campaigns had until the end of the day Wednesday to file with the Federal Election Commission.
Gaubert Oil expanding fuels business
The company has agreed to buy the wholesale and transportation division of Mississippi-based Buffalo Services, giving it a foothold in The Magnolia state.
Shohei Ohtani strikes out 10, Dodgers win in first pitcher-only game in 5 years
Dodgers on Deck: Friday, April 17 at Rockies
After an off day Thursday, the Dodgers open a four-game weekend wraparound against the Colorado Rockies starting Friday night at Coors Field in Denver. Tyler Glasnow takes the ball in the series opener on Friday. Right-hander Tomoyuki Sugano will be on the mound for Colorado. Friday game info
FDA to weigh easing limits on unproven peptides favored by RFK Jr. and MAHA supporters
The Food and Drug Administration will hold a meeting this summer to consider easing restrictions on more than a half dozen peptide injections, a group of unapproved therapies that have become popular among wellness influencers, fitness gurus and celebrities.
Shohei Ohtani to take mound as pitcher only for first time in 5 years
Live Results: New Jersey special congressional election to replace Mikie Sherrill
Residents of New Jersey's 11th Congressional District will have a representative in Congress for the first time this year after a special election on Thursday.
WATCH: First lady Melania Trump advocates for U.S. foster care system improvements at House roundtable
WATCH LIVE: Bessent, Loeffler join White House briefing on Tax Day
NFL Reporter Dianna Russini Resigns Amid Mike Vrabel Photos
Dianna Russini has resigned from The Athletic following a wave of controversy tied to photos of her with Mike Vrabel. The NFL Reporter Dianna Russini Resigns Amid Mike Vrabel Photos first appeared on The Blast
DOJ moves to erase seditious conspiracy convictions of Oath Keepers, Proud Boys in Jan. 6 cases
In court filings, prosecutors asked the U.S. Court of Appeals for the District of Columbia Circuit to vacate the convictions so that the government can permanently dismiss the indictments.
Postal Service union launches ad campaign promoting mail voting as Trump seeks to limit it
The 30-second message features a variety of voters, among them a busy farmer and a flight attendant, explaining why they cast their ballots by mail.
Trump won't back down from Pope Leo feud sparked by "60 Minutes" report, tells CBS News pontiff should stay out of politics
WATCH: Trump says he doesn't owe Pope Leo an apology after attacking him for comments on Iran
Archer teams with ‘Mandalorian and Grogu’ for first entertainment deal
As the meat snacks marketer expands, it is collaborating with the “Star Wars” universe for a campaign spanning retail, digital, social and out-of-home.
Hungarian Prime Minister Viktor Orbán ousted after 'painful' election result, ending 16 years in power
Hungarian voters on Sunday ousted long-serving Prime Minister Viktor Orbán after 16 years in power, rejecting the authoritarian policies and global far-right movement that he embodied in favor of a pro-European challenger.
Hungarian Prime Minister Viktor Orbán concedes defeat after 'painful' election result, ending 16 years in power
Hungarian Prime Minister Viktor Orbán conceded defeat on Sunday after what he called a ″painful″ election result, ending 16 years in power.
Polling stations close in pivotal Hungary election that could unseat long-time Prime Minister Orbán
Hungarians cast ballots Sunday in Europe's most consequential election this year, setting a record turnout in a vote that could unseat populist Prime Minister Viktor Orbán after 16 years in power.
Early results in Hungary's election show opposition party leading and Prime Minister Orbán's trailing
Hungarians cast ballots Sunday in Europe's most consequential election this year, setting a record turnout in a vote that could unseat populist Prime Minister Viktor Orbán after 16 years in power.
👑 Muriqi cements Mallorca legacy with brace against Vallecano
There's a new name atop the goalscoring pantheon in the Balearic Islands after Kosovar star Vedat Muriqi continued his scintillating 2025/26 form against Rayo Vallecano. The 31-year-old Prizren-born t...
Peru holds presidential election amid a decade of political tumult
In the span of a decade, Peru has seen nine presidents come and go. How has that affected this year's presidential race?
Exclusive: US intelligence indicates China is preparing weapons shipment to Iran amid fragile ceasefire, sources say
US intelligence indicates that China is preparing to deliver new air defense systems to Iran within the next few weeks, according to three people familiar with recent intelligence assessments.
NFL Draft 2026: Ohio State has 3 defenders who are worth top-10 picks, positional value be damned
Adyen tool speeds business payments
Financial operations at global enterprises remain “stubbornly complex,” as treasury teams juggle multiple banking and payment systems, the company said.
Fact-checking Trump and Hegseth's claims of U.S. 'victory' in the Iran war
Based on available information, the U.S. and its military partner, Israel, achieved significant battlefield wins, experts said. However, they said that calling it a "total victory" overlooks significant strategic setbacks for the U.S.
WATCH: Democratic presidential prospects flock to Al Sharpton's conference in New York
The Democratic Party's most ambitious politicians are courting African American activists in New York this week as the party's unofficial 2028 presidential nomination contest takes shape at an annual conference led by Rev. Al Sharpton.
Syrian Doctors Fight Infant Blindness After War
Syrian American ophthalmologists are banding together to improve pediatric tests for retinopathy of prematurity
Former Speaker Kevin McCarthy on American Politics and the GOP
Former U.S. House Speaker Kevin McCarthy participates in a discussion on the state of American politics and the Republican party at a forum hosted by The John F. Kennedy Jr. Forum at Harvard University.
Robbins mayor says village ‘open for business’ | ChicagoLIVE
Mayor Darren Bryant highlights new investments and development opportunities as the south suburban community looks to attract growth.
Sen. Graham seeks congressional review of any peace deal with Iran
Sen. Lindsey Graham said in a post on X that he looks forward to the architects of the proposal, including Vice President JD Vance, coming to Congress and explaining how the deal meets America’s national security objectives.
Iran hawks seem to fear Trump will give Iran too much
Some aspects of the mostly unclear deal are raising alarms among hawkish Trump allies.
WATCH LIVE: White House holds briefing as Trump agrees to two-week ceasefire in Iran war
Preds, Scripps Sports Announce Game-Changing Broadcast Partnership
Agreement Begins Next Season; Scripps Will Broadcast Predators Games Over the Air for Free
'The ultimate honour' - have your say on Maguire's new deal
Harry Maguire says playing for Manchester United is the "ultimate honour" after signing a new contract extension until June 2027, with the option for a further year. The 33-year-old central defender's current deal was due to expire at the end of this season. Maguire has made 266 appearances for United since signing for £80m from Leicester in 2019 - then a world-record transfer fee for a defender - and has since won the Carabao Cup and FA Cup with the club, as well as having a spell as captain.
Foldable iPhone hits engineering snags, shipment delays possible: sources
April-May 'extremely critical' period for Apple to resolve issues in time
Former NJ Gov. Chris Christie on Leadership and the Political Landscape
Former New Jersey Gov. Chris Christie (R) discusses leadership, the upcoming midterm elections, and the political landscape during a conversation hosted by the Institute of Politics at Harvard Kennedy School.
Activists and Policy Advocates on the Role of Civility in Politics, Media, and Everyday Life
Activists and policy advocates sit down for a discussion on the impact of civility on politics, the media, and everyday life. NYU Washington, DC, hosts this event.
Newly discovered fossils give scientists first look at the evolution of early complex animals
Newly discovered fossils have given scientists their first real glimpse of when Earth made a crucial transition from plants and unrecognizably simple animals to the complex creatures that took over the world and would eventually lead to us.
Nebraska softball sweeps Rutgers in Saturday doubleheader
Nebraska played host to Rutgers on Saturday in a conference doubleheader. The Huskers swept the day, defeating the Scarlet Knights 8-0 and 5-3.
Huddersfield Town vs Reading: 2025/26 Match Preview
In the first of two Easter fixtures, the Royals head north to take on playoff chasers Huddersfield Town.
Publicis sharpens sports marketing focus with 160over90 acquisition
Publicis CEO Arthur Sadoun described sports as the firm’s “next big bet” as it tries to bring cohesion to an increasingly valuable but fragmented market.
‘Orban constantly vetoes’: Europe braces for Hungary election
The practicalities of Hungary’s election may not matter as much as the psychological impact, say observers.
Democrats try new tactic to win a House seat in Utah — running as progressives in a red state
For decades, Democrats' only chance of getting elected to Congress from the conservative state of Utah was by convincing voters that they were sensible moderates. But the political landscape has changed, thanks to a redistricting shakeup that created a deep blue district anchored by Salt Lake City.
WATCH: Trump signs executive order to create national list of eligible voters
President Donald Trump on Tuesday signed an executive order to create a nationwide list of verified eligible voters, a move that is sure to draw legal challenges as the president continues to demand further restrictions on voting ahead of this year's midterm elections.
King County order targets housing, shelters and behavioral health
King County Executive Girmay Zahilay announced a new Executive Order on Tuesday aimed at boosting affordable housing and shelter options throughout the region.
NVIDIA's DLSS 4.5 Multi Frame Generation tech is now available to boost your Hz
After releasing DLSS 4.5's Super Resolution feature earlier this year, NVIDIA has released an update with two other DLSS 4.5 features designed to boost frame rates.
McCormick buys Unilever food business in $45B deal
The transaction creates a global spice and condiments giant with a portfolio that includes Hellman's mayonnaise and Frank's Red Hot.
Cowboys Daily Blitz: Dallas Faces New Questions About Pickens, Gary
Highlights! Itauma Erases Franklin With Vicious Uppercut
Rising boxing sensation Moses Itauma was back in action earlier today (Sat., March 28, 2026), as the undefeated (14-0) Heavyweight knockout artist took on Jermaine Franklin inside Co-Op Live in Manchester, England. Known for finishing his foes early — with 12 of his knockouts coming in under three rounds, eight in the first — it […]
These U.S. States Plan to Offer iPhone's Driver's License Feature
In select U.S. states, residents can add their driver's license or state ID to the Apple Wallet app on the iPhone and Apple Watch, and then use it to display proof of identity or age at select airports and businesses, and in select apps. The feature is currently available in 13 U.S. states and Puerto Rico, and it is expected to launch in at least seven more in the future. To set up the feature, open the Wallet app and tap on the plus sign in the top-right corner.
Washington Commanders unveiling new uniforms on April 15th
The Washington Commanders recently teased the unveiling of new uniforms on social media, and the reveal is scheduled for April 15th.
Israeli Military Kills Three Palestinian Men in Gaza, Health Officials Say
March 28 (Reuters) - The Israeli military killed three Palestinian men in Gaza on Saturday in two separate air strikes, local health officials and medics said, the latest round of deadly violence despite a U.S.-brokered ceasefire that is now more than five months old. Palestinian health ...
Iran-linked hackers have breached FBI Director Kash Patel’s personal emails
Hackers connected to the Iranian government accessed FBI Director Kash Patel’s personal email and posted materials — including photos and documents — taken from his account, a person familiar with the hack confirmed to CNN.
Federal judge upholds North Carolina photo voter ID mandate in win for GOP lawmakers
North Carolina’s photo voter identification law was upheld on Thursday, as a federal judge set aside arguments by civil rights groups that Republicans enacted the requirement with discriminatory intent against Black and Latino voters.
Democratic lawmaker asks judge to remove Trump's name from Kennedy Center
In a motion filed Wednesday, Rep. Joyce Beatty of Ohio argues that Congress was clear in its intent that the Kennedy Center is named for the late President John F. Kennedy — and no one else.
Reminder: Turn in Kootenai River Angler Science Program packets by April 1 for a chance to win prizes | Idaho Fish and Game
Burbot season is winding down, and now is the time to turn in your completed Angler Science Program packet. Packets must be submitted by April 1 to be eligible for raffle prizes.
Bank of America courts business clients in market-share push
To drive new client relationships in 50-some markets, BofA is hiring bankers and cultivating local connections, said Sharon Miller, the lender’s president of business banking.
Why Elite Athletes Train In The Heat & The Science Says You Should Too
The best part? You can do it at home.
Democrats revive allegations around Trump classified document case in latest political battle with Justice Department
Democratic Rep. Jamie Raskin asserted in a new letter that recently released Justice Department files show that prosecutors once considered whether President Donald Trump had improperly retained classified material relevant to his business interests after his first term.
UK bans crypto donations to political parties in bid to curb foreign influence
The move is likely to hurt the hard-right party Reform UK, which accepts crypto and has received large donations from a businessman living abroad.
Amex floats first new business card in 7 years
The bank is betting that a card without preset spending caps, plus 2% cash back, will win over businesses.
“Redemption Arc Complete” — Sunderland AFC Have Returned!
There’s no need to quietly ghost around town anymore, trying to hide who we are. It feels as if we’ve tunnelled under the Berlin Wall and to freedom.We are Sunderland AFC. And we’re back.
Tone, Humor, and the Performative Aspect of Politics
Senators John Kennedy (R-LA) and Peter Welch (D-VT) joined C-SPAN "Ceasefire" host Dasha Burns to discuss the roles of tone and humor in politics.
Why REI treats CX as a critical business function
The outdoor retailer is focused on doubling down on its differentiators, REI’s Clay Walton-House said. That means investing in its elevated services and member experience.
Trump places replica Christopher Columbus statue near the White House
A statue of Christopher Columbus has been placed on the grounds of the Eisenhower Executive Office Building adjacent to the White House, the latest effort by President Donald Trump's administration to recognize the controversial explorer.
Bursaries open for help with sports memberships
Children meeting certain criteria can get up to £200 from Epsom & Ewell Borough Council.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Ivan Herrera Hits First Home Run of Spring Training
Why the Trump administration is easing sanctions on certain Iranian oil stockpiles
Trump administration officials are making a desperate push to secure every available barrel of oil amid a worsening energy crisis — even if it means lifting sanctions on the very country that they’re fighting against.
USA TODAY Sports unveils 2026 ALL-USA Southwest Boys Basketball Team
Reese Alston, Kavian Bryant headline 2025-26 ALL-USA Southwest Boys Basketball Team.
Grassroots Climate Justice in Lebanon: Money, Power, and the Politics of Survival
Lebanon is caught in a cycle of financial meltdown, political instability, and climate change.
NVIDIA CEO defends DLSS 5 as gamers label it an 'AI slop filter'
Memes about the AI rendering model quickly spread after it was unveiled on Monday.
Arizona baseball loses at home to New Mexico
Though it lost two of three at Utah last weekend in its first Big 12 series, Arizona showed plenty of fight by tying or taking the lead in the 9th inning of each game. Unfortunately, that kind of effort didn’t come back with the Wildcats from Salt Lake City. The UA lost 6-3 to New […]
Trump's security pick Mullin poised to inherit a DHS beset by challenges
Immigration enforcement is at a crossroads. Disaster-hit states and their lawmakers are angry at delayed federal assistance. Frustrated travelers face long airport security lines due to a monthlong funding battle in Congress.
Grapefruit vs. Grapefruit Juice: Which is Better for Immunity and Fiber?
Whole grapefruit and grapefruit juice both have substantial amounts of vitamin C. However, whole fruit is a better way to get antioxidants and fiber that your body needs.
The New York Times
Gun-rights activists are a long-established force in Republican politics. But no candidate with a credible chance of reaching Congress has had a profile quite like Brandon Herrera, who has built a...
Robotics firm Intuitive Surgical says cyberattack compromised business, customer data
The company said an intruder accessed employee information, customer contact details and other records.
Oscars 2026: The moments we’ll be talking about all year
From history-making wins to uplifting musical performances, the Oscars celebrated outstanding films in “very chaotic, frightening times.”
Oscars 2026: Best red carpet looks from Demi Moore, Michael B. Jordan, Jessie Buckley and more
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Oscars 2026: Best red carpet looks from Demi Moore, Teyana Taylor, Jessie Buckley and more
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What are peptides, and are they safe? Here's what to know
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New Steelers Wide Receiver Michael Pittman Ready to Be Physical
WBC: USA advances to semis, Shohei Ohtani builds up pitching
The United States advanced to the semifinals of the World Baseball Classic with a 5-3 win over Canada at Daikin Park in Houston on Friday night. Will Smith, who has been splitting catching duties with Cal Raleigh, did not play on Friday. Clayton Kershaw did not pitch in any of the first five games of […]
Trump signs executive orders aimed at home affordability ahead of midterms
President Donald Trump on Friday signed a pair of executive orders aimed at showing his commitment to improving home affordability — a key issue for many voters going into November’s election for control of the House and Senate.
Direct-to-consumer health gets a jolt
DTC plays are being revitalized by investor demands for credible margins.
Seven reasons why Trump hasn’t won the Iran war
President Donald Trump is heading toward a vexing crossroads in Iran.
Seven reasons why Trump hasn’t won the Iran war
President Donald Trump is heading toward a vexing crossroads in Iran.
NATIONAL WOMEN’S SOCCER LEAGUE AND FRONT OFFICE SPORTS ANNOUNCE CONTENT PARTNERSHIP | News
FOS to showcase NWSL's signature events and moments, including 2026 NWSL Championship, presented Google Pixel, through business focused storytelling
Translate science into practice at ADA 2026 Scientific Session
The Scientific Session will focus on clear, actionable insights dentists can use to support their clinical decision-making.
WATCH: Asked what U.S. needs to do to end Iran war, Trump says 'more of the same'
Main Event set to join battle for Long Islanders' entertainment dollar
Main Event offers bowling, laser tag, arcade games, billiards, gravity ropes courses and other activities, as well as food and drinks.
Trump has call with Putin to discuss Iran war, Kremlin says
Putin’s foreign affairs adviser Yuri Ushakov described the conversation as “frank and businesslike” and said it lasted about one hour.
Ford Mustang Dark Horse SC Won't Be Cheap, Leaked Pricing Shows
Ford's powerful new Pony Car could cost $103,490 before taxes and fees.
Cincinnati Reds’ 3 Spring Training Standouts So Far
Formula 1: George Russell wins Australian Grand Prix after taking advantage of early VSC
Russell made his only pit stop 12 laps into the 58-lap race.
Appleton area high school sports results for Friday, March 6
High school boys basketball and wrestling teams continued WIAA postseason action.