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Jacobs Entertainment gets permits for sports fields, now under construction
2 News Nevada has gotten a look at new youth sports fields that are under construction in downtown Reno.
Utah Sen. John Curtis helps lead push to ban sports betting contracts on prediction markets
Utah Sen. John Curtis and California Sen. Adam Schiff are leading a push to make clear that sports prediction markets are indeed gambling.
I was on the Air Canada flight that crashed at LaGuardia
A 22-year-old student was on an Air Canada flight that crashed at LaGuardia Airport. He described the moment of the collision and the aftermath.
Will Blue Bloods Continue to Dominate Mach Madness in the NIL Era?
College basketball has changed because of NIL. The Big Ten has risen, old-school coaches have adapted, and the talent pool is deeper than ever.
Fall River's Day of Portugal announces dates, entertainment lineup for 2026
A festival that brings food, faith, and entertainment to the city will be returning once again. Day of Portugal Fall River, which takes place every year at the Gates of the City down near the waterfront on Ponta Delgada Blvd., is back in 2026. One of the more popular events in Fall River which
Kraken create One Roof Sports & Entertainment in expected pursuit of NBA expansion team
Kraken owner Samanatha Holloway created the umbrella brand One Roof Sports & Entertainment on Monday, a transaction that gives her a majority stake in Seattle’s Climate Pledge Arena and is a likely precursor to a bid for an NBA expansion franchise.
Kraken create One Roof Sports & Entertainment in expected pursuit of NBA expansion team
Kraken owner Samanatha Holloway created the umbrella brand One Roof Sports & Entertainment on Monday, a transaction that gives her a majority stake in Seattle’s Climate Pledge Arena and is a likely precursor to a bid for an NBA expansion franchise.
How AI is transforming health care and what it means for the future
New York’s LaGuardia airport closed after plane collision with fire truck kills two pilots
About 40 people taken to hospital after Air Canada Express crash, some with serious injuries
Does PBS ‘Count of Monte Cristo’ Make Big Book Changes?
A recap of Episode 1 of the Sam Claflin and Jeremy Irons-led adaptation.
The 3DFX Voodoo Lives Again In An FPGA
The 3DFX Voodoo was not the first dedicated 3D graphics chipset by any means, but it became the favourite for gamers among the early mass-market GPUs. It would be found on a 3D-processing-only PCI …
Hackaday Links: March 22, 2026
On Friday, Reuters reported that Amazon is going to try to get into the smartphone game…again. The Fire Phone was perhaps Amazon’s biggest commercial misstep, and was only on the market…
Nevada Wins Temporary Ban on Sports Betting on Kalshi
The prediction-market platform must obtain state gambling licenses and prohibit users under 21 to offer such contracts, a state court said.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Politics Now: March 22, 2026
This week on Politics Now with host John Langeler: Nevada is trying to lessen its reliance on fuel from California. We talk with the vice-chair of the committee tasked with determining how to do th…
School politics class: Biggest Nato allies reject Donald Trump’s Hormuz armada demand
Global governance
Guilty Gear: Strive version 2.00 update, Season 5 DLC characters Jam Kuradoberi and Robo=Ky announced
Arc System Works has announced the version 2.00 update for fighting game Guilty Gear: Strive, which will launch on April 9 alongside Season 5 downloadable content character Jam Kuradoberi.
Digimon Story: Time Stranger large-scale expansion DLC announced
Publisher Bandai Namco and developer Media.Vision have announced a large-scale expansion downloadable content for Digimon Story: Time Stranger. It will launch in 2027.
March heat wave draws Coloradans to the water, boosts seasonal business
A historic March heat wave sweeping across Colorado is sending residents outdoors in search of relief, with many trading winter sports for time on the water.
ESP32: When Is A P4 A P4, But Not The P4 You Thought It Was
We’re used to electronic parts of the same type staying predictably the same, sometimes over many years. An early Z80 from the mid 1970s can be exchanged with one from the end of production a…
'That's why there's 9 billion of us and not 9 billion of some other primate': Why our ability to adapt is humanity's 'superpower'
Live Science spoke with Herman Pontzer, an evolutionary anthropologist and author of the book "Adaptable," about the science of human diversity.
Skagit adds dozens of voluntary inpatient beds for mental health and detox
The new 48-bed facility in Sedro-Woolley is a project of the cross-county North Star collaboration
Tao Group to unveil OMNIA Dayclub & Skybar with special entertainment lineup
Tao Group Hospitality will officially unveil its new entertainment complex built from ground up at Caesars Palace next month.
Adaptive Sports & Recreation Expo taking place in Winston-Salem
The event will be held from 10 a.m. to 2 p.m. at the JDL Fast Track on Empire Drive in Winston-Salem.
Utica Zoo Celebrates Spring and Ramadan with Special Events
Families and friends are invited to celebrate the first day of spring and the end of Ramadan with a day full of activities at the Utica Zoo.
Claimants drop lawsuit against Gerry Adams over IRA bombings
Three people were suing ex-Sinn Féin leader for liability over IRA bombings in UK which left them injured
Google Unveils New Process For Installing Unverified Android Apps
It’s no secret that Google really doesn’t like it that people are installing Android applications from any other source than the Play Store. Last year they proposed locking everyone int…
Younger Chinese Americans are fighting to save traditions
Younger business owners are adapting to challenges their parents didn’t face: historic tariffs, dwindling adherence to tradition and lower foot traffic in a post-pandemic San Francisco.
How Muslim Businesses in New York Prepare to Celebrate Eid
From Fordham to Bay Ridge to Hollis, Muslim businesses get ready for Eid al-Fitr, the exultant celebration marking the end of the holy month of Ramadan.
How did these flowers evolve to survive a megadrought?
A multi-year megadrought in the Western U.S. has claimed untold populations of wild plants. Amid the conditions, some have survived. Scientists have produced a stunningly complete picture about how populations of one particular flower – the scarlet monkeyflower – made it through. In a new study published in the journal Science, a team of scientists spent decades studying and sampling select populations of scarlet monkeyflowers in California and Oregon. Through genetic sequencing, the team discovered that the populations that did best went through genetic changes in a short time period. This is known as rapid evolution. The team found that three of the populations that recovered the BEST adapted their stomata to open less, so they could conserve more water. Stomata act like a plant’s pores, managing gas exchange and water loss. This allowed the scarlet monkeyflowers to hunker down in the drought and survive. Interested in more stories about rapid evolution? Email us your question at shortwave@npr.org.Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.Listen to Short Wave on Spotify and Apple Podcasts.This episode was produced by Jeffrey Pierre, Rachel Carlson and Hannah Chinn. It was edited by Christopher Intagliata and Rebecca Ramirez. Aru Nair checked the facts. The audio engineers were Becky Brown and Robert Rodriguez.
WNBA CBA expected to raise pay for other women's sports leagues
While salary increases were a win, observers suggest revenue sharing in the new WNBA collective bargaining agreement will be transformative.
Judge rules the government overreached with transgender health care declaration
A federal judge has ruled that the government overreached when it declared certain types of gender-affirming care unsafe for young people.
Judge Rules US Government Overreached With Transgender Health Care Declaration
PORTLAND, Ore. (AP) — A federal judge said the government overreached by issuing a declaration that called treatments like puberty blockers and surgeries unsafe and ineffective for young people experiencing gender dysphoria, according to a ruling Thursday in Oregon. Judge Mustafa Kasubhai's ruling ...
Beyond Water: Why WASH Matters for Dignity, Health and Survival
Discover how Water, Sanitation and Hygiene (WASH) are vital to supporting and empowering refugees this World Water Day.
Super early 2027 Oscars predictions: Will Amy Adams finally win her first Academy Award?
Early 2027 Oscars contenders are already in the running for top awards. Here are EW's super early predictions for nominees, from Tom Cruise and Amy Adams to 'The Odyssey' and 'Dune: Part 3.'
Hermès doesn’t include a power adapter with its $5,150 charging case
You can charge your Apple Watch and iPhone for the cost of three MacBook Pros.
Accenture Collaborates with Microsoft to Bring Agentic Security and Business Resilience to the Front Lines of Cyber Defense
NEW YORK, March 19, 2026--Accenture today announced new assets and capabilities for its Adaptive Managed Extended Detection and Response (MxDR).
What to watch this week in New Orleans theater: ‘Gatsby,’ ‘Streetcar,’ ‘Little Shop,’ more
Step into the Jazz Age with a lavish musical adaptation of F. Scott Fitzgerald's classic tale at the Saenger Theatre. Don't miss the chance to witness Jay Gatsby's larger-than-life story come alive on stage!
Opinion: The dirty politics behind Judge Torgerson’s censure
Doug McMurdo: If Utah lawmakers were really worried about “the children,” where was their outrage when Stuart Adams ushered in a change to Utah’s statutory sexual assault law to protect a relative? It’s hypocrisy, plain and simple.
Samsung’s 65W Trio adapter can’t charge your Galaxy S26 Ultra at 60W
The 65W Trio adapter from Samsung can't charge the Galaxy S26 Ultra at 60W, and there's a reason behind this limitation.
Detroit-Canada bridges increasingly drawn into election-year politics
A new political ad and toll rates stirring questions about how North America's busiest crossing will be affected by new bridge.
Pittsburgh premiere of 'Eureka Day' stage comedy tackles vaccine politics
Jonathan Spector’s play “Eureka Day,” making its Pittsburgh premiere at City Theatre, depicts what happens to even a group of people who might seem highly compatible when a single hot issue scorches the earth between them.
Inside The Business of Beauty and Amazon Beauty’s Paris Dinner With Industry Leaders
Founders, C-Suite executives and creative leaders from brands including Augustinus Bader, L’Oréal, Louis Vuitton Beauty, Caudalie, Prada Beauty, Hermès, Sisley Paris and Vyrao Beauty joined The Business of Beauty and Amazon Beauty for dinner in the French capital.
Nevada defeats Murray State 89-75 in NIT
RENO, Nev. (AP) Vaughn Weems had 23 points in Nevada's 89-75 win over Murray State on Wednesday in the NIT.
Ozempic Is About to Go Generic in India, China and Canada
In India, China and several other nations, Novo Nordisk is on the verge of losing patent protection for its blockbuster weight loss drug, opening the door for cheaper competing versions.
Philadelphia Eagles' dynamic duo named one of NFL's best
The Philadelphia Eagles' dynamic receiving duo of A.J. Brown and DeVonta Smith was recently named one of the best in the entire NFL by Moe Moton of Bleacher Report. The pairing of Smith and Brown was named as the fifth-best wide receiver duo in the league, behind Ja'Marr Chase and Tee Higgins in Cincinnati, Puka Nacua And Davante Adams in L.A., CeeDee Lamb and George Pickens in Dallas and Amon-Ra St. Brown and Jameson Williams in Detroit.
UW Health resident creates adaptive crayons for children with disabilities
MADISON, Wis. — A physical medicine and rehabilitation resident at UW Health is reimagining crayons by creating adaptive crayons for people with developmental disabilities, stemming from her past experiences.
Ski For Life: Oregon adaptive sports program opens slopes to students with disabilities
An Oregon Adaptive Sports program allows young people with disabilities to participate in outdoors sports by providing them with adaptive equipment.
Federal investment fuels new labs for coastal science and restoration
The two are part of the Institute of Environment’s efforts to expand research on the Everglades, Biscayne Bay and other South Florida’s coastal ecosystems. The project received $11.5 million in funds.
SHINOBI: Art of Vengeance DLC ‘SEGA Villains Stage’ launches April 3 alongside free update
SHINOBI: Art of Vengeance downloadable content “SEGA Villains Stage” will launch on April 3 for $9.99 alongside a free update, publisher SEGA and developer Lizardcube announced.
NCAA president on sports betting, prediction market concerns as March Madness gets underway
LinkedIn partners with The Trade Desk for CTV ads
LinkedIn wants a bigger chunk of the streaming TV ad business. The Trade Desk will be its first demand-side platform partner for connected-TV ads.
A ‘Hail Mary’ for Earth, Built on Solid Science
Andy Weir discusses his science-fueled novel “Project Hail Mary,” which has been adapted into a film that opens in theaters on Friday.
Enzo Fernandez coy on Chelsea future following PSG loss
Chelsea midfielder Enzo Fernandez kept his cards close to his chest regarding a transfer away from Stamford Bridge following their Champions League exit at the hands of Paris Saint-Germain.The Argenti...
Stada Hunts for Major Consumer Health Deal After Record Profit
German pharmaceutical firm Stada said it’s ready to make a major consumer health acquisition as it books record profit and transitions to new ownership.
‘Just really unique’: Williamsport business preserves history — and finds surprise in basement
“You hate to see history disappear,” said Adam Roskowski, owner of Rosko’s Brew House in Williamsport. That was his motivation for buying the building now housing his craft beer pub at 601 Pine Street. After being vacant for years, Adam was keen to buy the Victorian – not just because of its historic charm but […]
A Massive Midterm Wave Isn’t Forming Yet. Here’s Why.
This is an era not just of hyperpartisanship, but of negative partisanship, in which partisans often hate the other side even more than they love their own. Many voters thus tend to see everything on a binary basis. Any given election outcome is seen as either a landslide victory or an unmitigated disaster. There is little appreciation, or even tolerance, for gradations between those outcomes.
We Saw Starfield's Big Overhaul and DLC - Is It Enough to Revive Bethesda's Space RPG?
Starfield is getting new DLC, Terran Armada, along with some major quality-of-life updates. And a PS5 version! We got an extended first look at everything on its way to Bethesda's big outer-space RPG.
Everything Coming in Starfield’s Free Lanes Update & Terran Armada DLC
April 7 marks the beginning of a new era for Starfield, with the game’s biggest free update yet, the all-new Terran Armada story DLC, and the official PlayStation 5 launch all arriving at once.
The scientist who warned that profit, not science, decides which drugs reach patients
In a Genomic Press Interview published in Brain Medicine, Dr. Gabriella Gobbi, Professor of Psychiatry at McGill University, Canada Research Chair (Tier 1) in Therapeutics for Mental Health, and President-Elect of the Collegium Internationale of Neuropsychopharmacology (CINP), delivers a pointed warning: the greatest threat to drug discovery is not scientific failure but a financing system that abandons effective, affordable treatments whenever they cannot promise sufficient returns to investors. Across a career that began in central Italy and moved through Sardinia and Montreal, Dr. Gobbi has generated landmark research linking adolescent cannabis exposure to depression, identified novel melatonin receptor mechanisms in sleep and pain, and launched psychedelic neuroscience before it became fashionable. The interview reveals a scientist whose best questions have always begun at the bedside, and whose most urgent fears concern the structures that stand between discovery and patients.
Chiefs Reportedly Make Trade With Jets For Former Steelers QB
Justin Fields is on the move again. On Monday, NFL insider Adam Schefter reported that the New York Jets are reportedly trading Fields to the Kansas City Chiefs in exchange for a 2027 sixth-round draft pick. The deal is still pending a physical. Other teams were reportedly interested in Fields, but his preference was to […]
Champions League burning questions: Could all six Premier League teams be eliminated?
With no English team winning their first leg, could the unthinkable happen in the Premier League?
Science Olympiad Results for Division A
Julius Cordes Elementary School, Team Blue, takes first place at the San Joaquin CountyScience Olympiad for Division A.
Kering adapts the presentation of its businesses, to align with its strategic model and organization
Kering - Press release - Segment reporting - EN - 16 03 2026 PRESS RELEASEMarch 16, 2026 KERING ADAPTS THE PRESENTATION OF ITS BUSINESSES, TO ALIGN WITH ITS STRATEGIC MODEL AND ORGANIZATION As part of the evolution of its strategy and organization, which will be presented in detail on April 16, 2026, during its Capital Markets Day, Kering announces a new segmentation of its businesses. This new presentation enhances the clarity of Kering strategic model, highlights the momentum of each of its bu
Apple Announces AirPods Max 2
Apple today unveiled AirPods Max 2, with key upgrades including the H2 chip, increased active noise cancellation, improved sound quality, and features such as Adaptive Audio, Conversation Awareness, Voice Isolation, and Live Translation. AirPods Max 2 have the same overall design as the original AirPods Max, with most of the new features coming from the upgrade to the H2 chip.
Providing Medicaid to immigrants who are children or pregnant is costing Colorado 611% more than expected
The state predicts that the Covering All Coloradans program will cost Colorado $104.5 million in the fiscal year that began July 1. Nonpartisan fiscal analysts estimated the cost would be $14.7 million.
Adams Named Palm Beach County Sports Commission's Coach of the Year
On Sunday evening, Keiser Women's Soccer Head Coach Alex Adams was named the Palm Beach County Sports Commission's Coach of the Year, announced during the Annual Palm Beach County Sports Hall of Fame Awards Celebration at the Palm Beach Kennel Club. The award is given based on a coaches accomplishments during the 2025 calendar year. Adams becomes the fourth Keiser head coach to win the award.
Play-off dream back on for Stoke?
Final Score's Sam Fletcher reflects on an important win for Stoke City and how it could reignite their promotion ambitions.
Assessing Caesars Entertainment (CZR) Valuation After A Sharp Recent Share Price Rebound
Why Caesars Entertainment (CZR) is on investors’ radar Caesars Entertainment (CZR) has drawn attention after a strong month for the stock, with a return of about 55%, prompting investors to reassess how its current share price lines up with recent business results. See our latest analysis for Caesars Entertainment. The recent 54.69% 1 month share price return has come after a steadier 16.87% 90 day gain. However, the 1 year total shareholder return is roughly flat and the 5 year total...
Farage Mega Donor Exposes Vulnerability in UK Politics
Britain’s biggest political donor is a crypto investor and aviation entrepreneur who has lived in Thailand for more than two decades. The £12 million ($16 million) that Christopher Harborne gave to Nigel Farage’s Reform UK last year wouldn’t be permitted in France, Canada or Ireland. If you’re sensing something askew with the UK’s rules for campaign finance contributions, you’re not alone.
Business majors preparing for the future
The third annual Arizona Statewide Business School Case Competition (ASBSCC), coming to Northern Arizona University, provides students with the opportunity to apply their knowledge and test their soft skills—communication, leadership, adaptability, networking and collaboration—by placing them in realistic business scenarios that demand quick thinking and effective teamwork. This collaborative effort between Arizona State University, the University of Arizona and NAU allows students to work across institutional lines to…
Strengthening One Health Field Epidemiology Capacity in the WHO South-East Asia Region
Recent public health emergencies—including the COVID-19 pandemic, recurrent zoonotic disease outbreaks, and the high level of antimicrobial resistance—have underscored the urgent need for strong, multisectoral field epidemiology capacities. This reinforces the importance of a workforce equipped with One Health field epidemiology competencies. To address this need, WHO works with the Food and Agriculture Organization of the United Nations (FAO), the United Nations Environment Programme (UNEP), and the World Organisation for Animal Health (WOAH), as part of Quadripartite Alliance for One Health, to strengthen field epidemiology training programmes using a One Health approach.These efforts are aligned with WHO SEARO’s Strategic Framework for Action for Strengthening Surveillance, Risk Assessment and Field Epidemiology and the Regional Roadmap to Advance Field Epidemiology Capacities 2025–2029 emphasize workforce development, multisectoral collaboration, and enhanced preparedness for health emergencies. With funding from the Pandemic Fund, The Competency for One Health Field Epidemiology (COHFE) integration within Field Epidemiology Training Programmes (FETPs) or similar initiatives has been initiated in Bangladesh and India and is planned in Sri Lanka.BangladeshIn Bangladesh, COHFE is being adapted to strengthen the Field Epidemiology Training Programme, Bangladesh (FETP-B) Advanced programme. Initiated in July 2025 and led by the Institute of Epidemiology, Disease Control and Research (IEDCR), the process brought together stakeholders from human, animal, and environmental health sectors, academia, and laboratories.A Multisectoral Working Group (MWG) was established to guide implementation, conduct readiness assessments, and identify opportunities to institutionalize One Health collaboration. Through national multisectoral consultations and a competency prioritization workshop held in Dhaka in November 2025, stakeholders identified priority technical competencies for surveillance, outbreak investigation, data analysis, and risk assessment, alongside functional competencies related to leadership, coordination, and the laboratory–epidemiology interface. The process also surfaced systemic barriers—such as challenges in data sharing and limited joint investigations—enabling targeted recommendations. These outcomes are guiding curriculum revision, the introduction of One Health simulations and joint field exercises, and the development of a national multisectoral mentorship pool, with updated training materials expected to be implemented in the upcoming cohort.Figure 1. Competency prioritization involving multisectoral stakeholders“COHFE represents a significant step forward in operationalizing the One Health approach. The collaboration between national institutions and the Quadripartite partners is critical for building resilient systems to address complex health challenges in the region.”, Prof. (Dr) Tahmina Sirin, Director, Institute of Epidemiology, Disease Control and Research (IEDCR), Bangladesh.Aligning India’s One Health Training with COHFEIn India, the National Centre for Disease Control (NCDC) has strengthened One Health workforce development through its SectorConnect initiative. WHO supported a comprehensive competency mapping and curriculum review to align the Field Epidemiology Programme in One Health (FEP-OH) with all 14 COHFE domains. The review identified strong foundations while generating actionable recommendations to strengthen One Health learning outcomes, expand joint field-based learning, and enhance competency-based assessment. These improvements are informing programme refinement and phased scale-up across additional states.Figure 2. Strengthening learning outcomes for the SectorConnect FEP OH CurriculumThrough these efforts, WHO SEARO will continue to support countries to move from separate sector-based training toward an integrated, impact-driven One Health field epidemiology workforce capable of addressing complex health threats at human-animal-environment interface.ReferencesFood and Agriculture Organization of the United Nations, World Health Organization, & World Organisation for Animal Health. (2024). Competencies for One Health field epidemiology (COHFE) framework. https://www.who.int/publications/i/item/9789240080058World Health Organization. (2023). Strategic framework for action for strengthening surveillance, risk assessment and field epidemiology for health security threats in the WHO South-East Asia Region. WHO Regional Office for South-East Asia. https://www.who.int/publications/i/item/9789290210030World Health Organization. (2024). Regional roadmap to advance field epidemiology capacities in the WHO South-East Asia Region 2025–2029. WHO Regional Office for South-East Asia. https://www.who.int/publications/i/item/9789290229544
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