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Results for " estimate " 843 found 🔀 AI-powered Shuffle

Oops, Scientists May Have Severely Miscalculated How Many Humans Are on Earth

While most estimates place the current human population at around 8.2 billion, a study suggests we might be vastly underrepresenting rural areas.

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Jun 10 • 9:44 AM EDT • Science • yahoo.com
UVM Health cuts 142 jobs — an estimated $9 million in staff positions

The cuts come as the hospital network faces an expected $300 million budget deficit and increasing pressure to cut costs.

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Jun 9 • 2:07 PM EDT • Health • vtdigger.org
High construction costs delay plans for Visit Baton Rouge office relocation

Visit Baton Rouge estimated the renovation of 232 Lafayette St., in shell condition, to cost $5 million, but the four contractors’ estimates range from $1.6 million to $2.6 million more than the estimate.

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Jun 9 • 1:57 PM EDT • Business • theadvocate.com
Truist says Meta has found its next $20 billion business, stock set to gain more than 40%

Analysts at Truist estimate Meta's new subscription model could generate over $20 billion in revenue by 2030.

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Jun 9 • 12:12 PM EDT • Business • cnbc.com
Weapon Systems Acquisition: Beyond Business as Usual—Using Leading Practices to Curb Waste and Save Billions

Since 1990, DOD’s costliest weapon programs have consistently exceeded cost estimates and delivery schedules—wasting billions of dollars and decades...

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Jun 9 • 8:00 AM EDT • Business • gao.gov
Stamford Health plans new cancer center, behavioral health facility

Construction is set to start in 2027, with estimated costs around $275 million.

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Jun 7 • 5:00 AM EDT • Health • ctinsider.com
Assessing Caesars Entertainment (CZR) Valuation As Digital Growth Supports A 12.4% Undervaluation Estimate

Recent performance snapshot Caesars Entertainment (CZR) has drawn fresh attention after recent trading, with the stock last closing at $29.20. Short term performance has been mixed, with a slight decline over the past day but a small gain over the past week. See our latest analysis for Caesars Entertainment. At around $29.20, the stock has recently posted a 1-month share price return of 5.19% and a year to date share price return of 23.94%. The 1-year total shareholder return of 13.49%...

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Jun 6 • 2:17 PM EDT • Entertainment • simplywall.st
Nicholas M Ryan

Industry: Real EstateAge: 70 (Crain's estimate)Undergrad: Rose Hulman Institute of TechnologyProfessional/civic: National Multifamily Housing Council; Institute for Community

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Jun 6 • 11:12 AM EDT • Business • chicagobusiness.com
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South Florida businesses question whether FIFA's economic boost estimate for the World Cup will become reality

FIFA estimates the seven games played in the area could generate $1.3 billion in economic activity.

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Jun 5 • 7:04 PM EDT • Business • cbsnews.com
High-Signal Publisher
Healthy aging in the LGBTQIA+ community

An estimated 3 million American adults age 50 and older identify as LGBTQIA+,* and that number is expected to grow to about 7 million by 2030 as the U.S. population continues to age. While LGBTQIA+ adults in general are more likely to experience certain health problems than the general population, this may be especially true of older adults because of the cultural conditions they have experienced in their lifetimes.

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Jun 5 • 3:58 PM EDT • Health • phillyvoice.com
World Food Safety Day 2026: EFSA advancing safer food through science

Every year, unsafe food causes illness, long-term health problems and economic harm for millions of people worldwide. World Health Organization estimates that contaminated food causes 866 million illnesses and 1.52 million deaths annually, affecting nearly one in nine people globally. For World Food Safety Day on 7 June 2026, EFSA is reaffirming its commitment to turning scientific evidence into safer food for everyone.

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Jun 4 • 8:00 PM EDT • Science • efsa.europa.eu
U.S. Q1 2026 worker productivity revised sharply lower

Nonfarm business productivity grew at just a 0.3% annualized rate in the first quarter, down from an initial estimate of 0.8%

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Jun 4 • 10:47 AM EDT • Business • qz.com
James Bond game 007 First Light sales estimated to have reached an impressive milestone a week after launch

The new James Bond game from Hitman developer IO Interactive seems to have been a big success. Does that mean we're going to get more of them?

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Jun 4 • 5:38 AM EDT • Technology • eurogamer.net
Unsafe food causes 866 million illnesses and 1.5 million deaths annually, young children at highest risk

Children aged less than five years face almost three times the risk of illness from unsafe food than older children and adults, according to new estimates released today by the World Health Organization (WHO).

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Jun 3 • 8:00 PM EDT • Health • who.int
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Why Needham Still Sees Upside in Flutter Entertainment plc (FLUT)

Flutter Entertainment plc (NYSE:FLUT) is one of the best sin stocks to buy now. On May 7, Needham reiterated its Buy rating on Flutter Entertainment plc (NYSE:FLUT) but lowered its price target to $135 from $150. The research firm also lowered its adjusted EBITDA estimates of the company by 7%. The price target cut is […]

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Jun 3 • 1:48 PM EDT • Entertainment • finance.yahoo.com
May's top PlayStation games by copies sold

Yesterday’s State of Play gave us an idea of where PlayStation’s heading next. But we’ve had our May estimates for a couple of days now (we always update our data daily for clients), so it’s time to look at what performed best on PlayStation last month. We’ve got a new IP at the top, two evergreens doing their evergreen thing, FC26 smashing it ahead of the World Cup Plus pivot, and a quiet but promising result for Lego Batman. Let’s have a look at the state of Play…Station’s top games for May. 007 takes #001 007 First Light sold 1M copies on PS5 in May, easily making it the month’s top PS5 game by copies sold. Over 80% of those May copies were digital, which is broadly in line with where PlayStation’s digital share has settled for new releases this year. To date, 007 First Light has sold through 2.2M copies across platforms (so no unsold retail copies in that figure). The platform split is 55.1% PS5, 33.1% Steam, and 11.8% Xbox (console, Windows, and cloud combined). In gross revenue terms, 007 First Light has generated $150M. Owing to regional pricing and audience composition differences, the consoles make up a higher share of revenue than they do copies. Of the $150M, 60.5% came via PlayStation, 27.6% via Steam, and 12.9% via Xbox. Part of this is because over two-thirds of 007 First Light‘s PlayStation audience is in North America (43.4%) or Western Europe (23.2%), where local currency means the game generates more revenue per player. On Steam, under half of First Light‘s audience is from those same regions (31.8% North America, 15.1% Western Europe). As we covered in last week’s 007 Steam piece, the Steam version is pulling in higher-than-expected numbers in China, which now accounts for 17.3% of First Light‘s Steam audience. 007 is the equivalent of $44 USD in China, which is roughly 37% cheaper than the US price and about 44% cheaper than Western Europe. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe The crossover data backs up what we’ve seen all year about launch-window cohorts. 11% of PS5 players who played 007 First Light in May also played Lego Batman: Legacy of the Dark Knight, which launched just a few days before. Last month was a great month for Denmark! IO Interactive is Copenhagen-based, and Lego Group is headquartered in Billund (TT Games is UK-based but produces work under Lego Group licence and direction). Speaking of which… A very blocky #2 and #3 Minecraft sold another 788K copies on PlayStation consoles last month. Business as usual, since Minecraft hasn’t sold fewer than 760K copies in a single month all year. With over 350M copies sold across all platforms, Minecraft is the best-selling game in history and one of the strongest brands in the world. Every month, a new cohort of children reaches Minecraft age, which guarantees a constant volume of new sales regardless of what the broader market is up to. The demographic refresh rate is truly impressive, with the audience renewing itself faster than it’s churning. Lego Batman: Legacy of the Dark Knight shifted 757K copies on PS5 last month, bringing its lifetime total on the platform to over 800K. Across all platforms, Legacy of the Dark Knight has now passed 1.5M sold through, so PlayStation accounts for over half of the game’s players. The May crossover data for Legacy of the Dark Knight on PS5 is also useful. 27% of those players also played Fortnite, 16% Roblox, 16% FC 26, and 14% NBA 2K. That’s the household-and-family cohort showing up, plus the launch-window cohort of core gamers who buy practically everything. FC 26 gets players through the door ahead of the World Cup FC 26 sold 411K copies on PlayStation last month (90% via PS5), the fewest copies FC 26 has sold all year and down heavily from April’s 700K. Part of this dropoff is because FC 26 has been available as a PlayStation Plus monthly game since 6 May, cannibalising premium sales. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe The strategic logic is straightforward for EA, which is sacrificing premium unit sales in May to build up the player base ahead of the FIFA World Cup, which kicks off on 11 June. Obviously, a bigger player pool going into the tournament means a bigger pool of potential Ultimate Team spenders during the period when football attention is at its peak. The early returns are around what you’d expect, with 4.4M new players accessing FC 26 via PS Plus last month – a substantial new spender pool. Anecdotally, a few of my mates who were ‘’skipping FIFA and Ultimate Team this year’’, were drawn back in via PS Plus. Lo and behold, one of them is buying packs like it’s going out of fashion. Whether this is all a smart trade for EA depends entirely on the Ultimate Team conversion rate over the next six weeks. Either way, the short-term engagement impact on the game as a whole is evident. FC 26‘s MAUs hit a record 24M on PlayStation in May, up 30% from the previous record set in April. GTA V does what GTA V always does Rounding out the top five is another evergreen title. Grand Theft Auto V shifted another 387K copies on PlayStation last month. No matter what else is happening in the industry, GTA V keeps pulling players in. It’s sold another 1.8M copies on PS5 in the first half of this year alone, helping the franchise pass the 230M-sold milestone across all platforms. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe I have a theory that Minecraft and GTA V are doing the same thing at different demographic levels. Both are functioning as generational gateway games that the audience ages into faster than it ages out of. Minecraft captures kids around age 6-10, GTA V captures much of the same audience around age 12-15 (unofficially, of course). The crossover data suggests this: 40% of GTA V‘s monthly PlayStation players typically play Fortnite in any given month, while 30% play Roblox. Household accounts aside, that’s not the original GTA V audience from 2013. Of course, the under-12 audience would love to get their hands on GTA, too. It’s always been the way of things, and some parents are happy to oblige. Mine did too back in the day, and I turned out just fine. Right? Right!? Want to get your hands on our data for yourself – for free? We’re offering a free trial of our platform for games companies. Send us a message here, or reply to this email, and we’ll set you up. The last word Reply to this email – or reach out here – if you have any feedback for the newsletter – or want to request a game for us to cover. [Alinea Analytics boasts the most accurate PC and console estimates in the business. Game makers use our platform to understand their audience, keep an eye on the competition, monitor sales trends, and spot new opportunities. We equip game studios and financial institutions with accurate data and the confidence to make smarter, data-driven decisions. Want to talk about all things games market data? We’d love to chat!]

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Jun 3 • 10:49 AM EDT • Technology • alineaanalytics.substack.com
Macquarie Sees World Cup Boost Driving Betting Growth, Favors Flutter Entertainment (FLUT)

Flutter Entertainment (NYSE:FLUT) stands out as one of the biggest potential beneficiaries of the 2026 FIFA World Cup, according to Macquarie, which expects the expanded tournament to generate a substantial increase in global sports betting activity and provide a meaningful earnings tailwind for leading operators. The investment bank estimates that betting volumes tied to the competition could exceed $50 billion worldwide, creating a favorable backdrop for major sportsbook and online gaming comp

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Jun 3 • 7:04 AM EDT • Entertainment • finance.yahoo.com
SpaceX valuation should be nearly 50% lower than estimates: Morningstar

Morningstar says there are likely to be better opportunities to buy the stock in the months after the IPO this month.

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Jun 3 • 5:00 AM EDT • Business • businessinsider.com
These States Report the Most Whooping Cough Cases in 2026

More than 4,700 cases of whooping cough have been reported to the Centers for Disease Control and Prevention this year. It’s on track to be fewer cases than last year when the CDC estimated more than 28,000 cases. But it’s still a significant number, especially for the states seeing the worst of it.

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Jun 2 • 4:56 PM EDT • Health • usnews.com
Apple's MacBook Neo is winning over a new generation of buyers

The MacBook Neo shipped 1.1 million units in its first weeks on sale, IDC estimates, as Apple pushes deeper into the mainstream laptop market.

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Jun 2 • 10:39 AM EDT • Technology • techcrunch.com
The Adventures Of Elliot: The Millennium Tales Estimated Playtime Revealed

It apparently takes "around 30 hours"

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Jun 1 • 10:55 PM EDT • Technology • nintendolife.com
Towards a responsive health system and equitable access to quality RMNCAH services

Indonesia’s vast geography and sociocultural diversity shape the delivery of reproductive, maternal, newborn, child and adolescent health (RMNCAH) services in ways that are both enabling and challenging. Across provinces, significant variation has been observed in how services are planned, resourced, and delivered. These variations in service standards and quality are felt daily in the lives of women, newborns and adolescents. Despite these challenges, progress is visible. National estimates show a drop in maternal mortality ratio, from 331 to 140 per 100 000 live births since 2000, signaling improvements in care quality and access. Fertility has stabilised and contraceptive use has grown, yet unmet reproductive health needs persist, and adolescent pregnancies continue to reflect early marriage and limited access to youth-friendly services.To better understand how Indonesia’s health system has evolved under decentralisation, the Ministry of Health, supported by World Health Organization (WHO), United Nations Population Fund (UNFPA), the United Nations Children’s Fund (UNICEF), IPAS and the Asian Development Bank (ADB), conducted a joint external review of RMNCAH programmes. This review draws on multiple sources of evidence, including existing literature, policy documents, national health system data, as well as field visits to six selected provinces to represent Indonesia’s geographic and administrative diversity. During the field visits, review teams observed service delivery in health facilities, spoke with health workers and local leaders and met mothers and families to understand how RMNCAH policies are operationalised. One of the challenges identified was the management of low birthweight (LBW) infants, a major contributor to neonatal deaths, under resource constraints. One midwife described a severe case of extremely LBW twins, one stillborn and the other died after three days of care. She recalled how the surviving infant struggled to swallow and may not have received breast milk, while simultaneous emergencies required the team’s attention, affecting the care provided to the infant.A subsequent review of the case by the district health office revealed insufficient antenatal care, fragmented maternal medical history due to population mobility, referral delays, limited provider capacity in neonatal intravenous access and a heavy workload that constrained proper newborn monitoring. These insights informed recommendations to strengthen both system-wide and service-level responses. Since the early 2000s, Indonesia’s decentralisation initiative has given much of the responsibility for funding, staffing and managing health services to regional governments. While the Ministry of Health sets national clinical standards, daily management of public health facilities falls under regional authorities through the Ministry of Internal Affairs. While this arrangement allows services to be tailored to local needs, it also depends heavily on local capacity for planning, budgeting and management. Health facilities and district health offices are better positioned to translate national priorities into local action when they have access to consistent technical support, helping health workers manage resource constraints and infrastructure gaps.The complexity of Indonesia’s health system governance is no easy feat to navigate. Understanding these dynamics is essential to strengthening policy, improving coordination and ensuring more equitable access to services across Indonesia. Under the leadership of Ministry of Health, recommendations from this exercise will be key in guiding the nation’s roadmap to an equitable and quality health system for RMNCAH.Written by Edit Oktavia Manuama, National Professional Officer (Maternal, Newborn, and Child Health), and Jessie Yunus, National Professional Officer (Gender, Rights, Equity, and Disability Inclusion)

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Jun 1 • 8:00 PM EDT • Health • who.int
More young people are looking to AI chatbots for mental health help

A new survey estimates 8 million young people use AI chatbots for help when stressed, angry or sad, an increase from 2024.

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Jun 1 • 11:00 AM EDT • Health • sciencenews.org
Your kitchen sponge is releasing microplastics every time you wash dishes

Kitchen sponges release microplastics as they wear down during everyday use, with some sponge types shedding far more than others. Researchers estimated that millions of households could collectively release hundreds of tons of microplastics annually.

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Jun 1 • 8:00 AM EDT • Science • sciencedaily.com
New York state requests disaster declaration after April frost impacts crops

Gov. Hochul’s office says a survey conducted by the state Department of Agriculture and Markets estimates that growers are facing anywhere from 15% to 100% losses to date.

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May 31 • 11:17 AM EDT • Politics • spectrumlocalnews.com
Congo Expands Ebola Testing as Outbreak’s Real Scale Eludes Officials

The number of confirmed Ebola cases in the Democratic Republic of Congo has climbed to 260 as officials updated their estimates of the outbreak’s size and international health organizations warned of the risk of further spread.

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May 30 • 9:26 PM EDT • Health • bloomberg.com
A silent kidney crisis is spreading far faster than experts expected

A sweeping global study found that chronic kidney disease now affects nearly 800 million people and has become one of the world's leading causes of death. Often silent in its early stages, the condition is also a major contributor to heart disease and may be even more common than current estimates suggest.

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May 28 • 8:00 PM EDT • Science • sciencedaily.com
Dell stock explodes higher after blockbuster AI-fueled earnings

Dell is among a handful of 2000s-era computer companies that have gotten a major boost from AI. The company crushed analysts' earnings estimates.

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May 28 • 6:23 PM EDT • Business • businessinsider.com
The Science of Flavored ENDS: A Response to Bloomberg, Durbin, and the Senate Letter on FDA's Recent Actions

The stakes: half a million American lives every year Cigarette smoking kills roughly 480,000 Americans annually, and nearly 28 million American adults still smoke. Peer-reviewed population modeling estimates that displacing combustion with substantially less harmful nicotine delivery would avert between 1.6 and 6.6 million premature deaths and recover 20.8 to 86.7 million life-years by 2100....

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May 28 • 12:55 PM EDT • Science • rstreet.org
UToledo Scientists Develop New Method to Estimate Hidden Species

The new model for collecting species data within ecosystems is published in the May issue of Ecological Informatics.

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May 28 • 4:00 AM EDT • Science • news.utoledo.edu
Ebola, chemical plants and health, hantavirus, common colds, heat and more

As they say, bugs have ears. Public health has had a relentless May. Chemical plant (near) explosions, Ebola, hantavirus, and that's before you even get to the usual suspects: common colds, heat, and ticks. Here’s an attempt to keep you up to speed and, more importantly, what it means for you and your community. But first, an announcement: World Cup The World Cup starts in 15 days (not like anyone is counting down), and we are hanging TVs in the Health Security Operations Center. It’s going to be a gorgeous, chaotic celebration of basically every culture on earth. And it’s going to take a team effort—from communities to individuals, from public health to health care—to keep people healthy. That’s where you come in. If you’re going to the games or live within 30 miles of a stadium, we would love to hear from you. Sign up for a weekly survey here. Thanks to the more than 1,280 people who have already signed up…you will be hearing from us soon!! Global disease “weather report” Hantavirus: Two more cases The global count of cruise ship passengers with hantavirus has now increased to 13 cases (11 confirmed), with three deaths. The two new cases are overseas and among people who were already quarantining: A crew member in the Netherlands. A Spanish national passenger who was quarantining at home tested positive through daily monitoring. They are now in a biocontainment unit. In the U.S., everyone remains negative. There may be more cases, given that the incubation period of hantavirus (the time from exposure to infection) is 45 days. But this week, we will reach a major milestone: the median incubation window is 18 days, and that will pass on May 29. What this means for you: Your risk from this cruise ship outbreak remains essentially nil at this point. Ebola rages on in Central Africa Big thanks to Dr. Craig Spencer, a humanitarian physician who has treated and survived Ebola, for jumping in to provide the YLE community with an update. Craig, take it from here… The combined confirmed and suspected Ebola cases in DRC are now more than 1,000. All signs are pointing to a very long and catastrophic outbreak in Central Africa: This is a vast undercount. We know this because the test positivity rate is hovering around 50%, only 20% of contacts are being traced (and in some areas, no contacts at all), and more cases keep popping up with no known connection. This all points to widespread and undetected community transmission. This is in only a week of detection. Compared to previous outbreaks, the growth is very fast, as the huge West Africa outbreak in 2016 was first detected at 49 cases and rose to 208 cases a month later. It took four months for that outbreak to reach the size of the current one in the DR Congo. The cases are spread out across 16 health zones. There are now multiple epicenters, making containment very difficult. Next door in Uganda, the case count is seven. While this number is low compared to DRC, a concerning development is that two health care workers recently tested positive with uncertain exposure histories. If they weren’t treating known Ebola cases, this means it’s spreading undetected in Uganda as well. On the ground, backlash, including the burning of health centers, has emerged, a pattern seen in nearly every outbreak and rooted in deep community distrust. It often stems from outside actors working in communities without fully understanding or addressing local priorities. Affected populations may recognize the severity of Ebola while still holding other concerns as more pressing, such as where their loved ones are buried. Community trust is essential to an effective response, but difficult to build during an active emergency. It is best established long before a crisis begins. U.S. priorities are made clear, and may backfire. The U.S. Administration has shown that its first priority is keeping Ebola out, with helping end the outbreak in the DRC a secondary concern. That's meant travel restrictions broader than anything we've imposed before — covering travelers from across the region, and reportedly some green card holders and permanent residents as well. For example, just these past two days, news broke that high-risk American travelers will be subject to a mandatory quarantine in Kenya before they are allowed to return. If an American is infected, the U.S. government plans to send them to a hospital it is standing up from scratch in Kenya. (Currently, Americans who were in the area are allowed to return but are diverted to three airports—Houston, Atlanta, and DC—for further screening.) Past administrations have used travel notices and stepped-up screening; this goes much further. At first blush, these strict precautions may sound prudent. But this approach could backfire in three ways: Restrictions this blunt give people every reason to hide where they’ve been and whom they’ve been near — making the people we most need to find harder to track, not easier. They also breed a false sense that this is someone else’s problem. But diseases are humbling. They find the small cracks in even the most impenetrable-seeming defenses. Lives lost. There is no treatment for this Ebola strain, which means survival depends heavily on the quality of the health system. We have that system in the States, but we are choosing not to use it for infected Americans. This is unbelievable and infuriating. (See a deeper dive from me here.) The only real way to lower the risk to Americans — and everyone else — is to end the outbreak in the DRC and across the region. What this means for you: If you have travel plans to this region, it’s time to cancel them. This is a high-risk situation in Central Africa, and CDC released a Level 4 Travel Advisory. There is also great uncertainty if and when the Administration will let you back in. To the general public in the U.S., your risk remains very, very low right now. U.S. disease “weather report” Ticks: past peak season? Good news, especially for people in the Northeast and Midwest: tick numbers continue to decline. Though we are at the peak of the season, this unusually early year is trending favorably. Heat-related illnesses in the North Heat risk is certainly not blanketing the entire country yet, but this week it will be moderate in the Midwest and the Southeast. What this means for you: Be sure to check the CDC HeatRisk tool. A red day isn’t the best day for that soccer game for a kid with asthma, and a stretch of orange days is a great time to check on your elderly neighbor. Common colds surging As far as respiratory viruses go, the only thing really going around right now is the common cold. It is higher this year than last year, but should peak very soon before returning this fall. Spotlight: Chemical plants Over the weekend, YLE California covered the serious situation that unfolded around a chemical plant in Orange County, California. Thankfully, the worst-case scenario (a chemical explosion) was mitigated, but only through luck. The health implications in a densely populated area could have been catastrophic. As the situation was winding down, another chemical explosion struck Washington State. This one was fatal. Health officials say the risk to surrounding residents from chemicals in the air and ground remains low, though the community deserves far greater clarity. Clean air and clean water consistently rank as Americans’ top public health concerns — yet when chemical disasters strike, communities are too often met with reassurances rather than transparency and accountability. Residents near the 2023 East Palestine, Ohio train derailment, for example, are still waiting to understand the long-term impact on their health, with few clear answers. What this means for you: Many are wondering if facilities processing potentially dangerous materials are in their neighborhoods. This interactive map allows you to enter your ZIP code and see all facilities monitored by the EPA, including any violations. Good news Ebola vaccines and treatment for the Bundibugyo species are in development. Two vaccine platforms are being explored, at least one of which may be deployable in as little as 2 months. One vaccine is being developed by Oxford, and the other uses the same biotechnology as the FDA-approved Zaire species of Ebola. (It may provide cross-protection, but it’s unclear at this point.) On the treatment side, two promising monoclonal antibody cocktails are likely to be deployed, though doses are limited and logistical hurdles remain significant challenges. Anni over at The Biotech Tea had a great explainer about the Ebola vaccine gap, if you want to read more. [ The Biotech Tea The Ebola vaccine gap, reading vessel damage, & the Makary exit 🗝️ Paid subscribers get the Biotech Term of the Week at $30/year (~$2.50/month). I try to keep it intentionally accessible, but if cost is ever a barrier, send me a message. A few people asked about expensing your subscription, so I put together a short email template… Read more 6 days ago · 10 likes · Annicka Evans, PhD ](https://www.thebiotechtea.com/p/the-ebola-vaccine-gap-reading-vessel?utm_source=substack&utm_campaign=post_embed&utm_medium=web) Polycystic ovary syndrome (PCOS) has been officially renamed polyendocrine metabolic ovarian syndrome (PMOS), following more than a decade of debate and input from roughly 22,000 clinicians, researchers, and patients worldwide. This is good because the old name was medically misleading, leading to patients without visible cysts being dismissed or overlooked entirely. The WHO estimates that 70% of people with the condition remain undiagnosed. A more accurate name should improve recognition, reduce stigma, and ultimately help the millions of people living with this condition get diagnosed and treated sooner. Poll Loading... Bottom line Public health situations are everywhere right now. Staying healthy takes public health professionals and systems working tirelessly behind the scenes and each of us showing up for our neighbors and communities. Love, YLE Big thanks to Ed Nirenberg for staying on top of the Ebola vaccines, Hannah Totte for all the figures, Dr. Craig Spencer for the Ebola insight, and Dr. Matt Willis for covering the chemical situation in CA. Your Local Epidemiologist (YLE) comprises a team of experts, ranging from physicians to immunologists to epidemiologists to nutritionists, working together with one goal: to “Translate” ever-evolving public health science so that people are well-equipped to make evidence-based decisions. YLE suite of newsletters reaches over 475,000 people across more than 132 countries. This newsletter is free to everyone, thanks to the generous support of fellow YLE community members. To support the effort, subscribe or upgrade below: Subscribe

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May 27 • 7:43 AM EDT • Health • yourlocalepidemiologist.substack.com
Semiconductor decoupling. Powell's politics. Industrializing Ogaden. Free trade and the Magna Carta.

Thank you for opening your Chartbook email. Feliks Topolski, 1907-1989 8th Army’s Front, Italy 1944 Semiconductor decoupling Source: FT One thing that Jerome Powell deeply understood is that chairing the Fed under current conditions is a deeply political job. “Powell has successes and mistakes to his name. But he stands out as having thought more carefully about the Fed’s democratic legitimacy than any chair since Paul Volcker,” said Paul Tucker, a former deputy governor at the Bank of England, referring to the Fed chair who successfully fought the great inflation of the 1970s and early 1980s. … While Powell was at the Treasury in the early 1990s, he watched Alan Greenspan build relationships within the government. That convinced Powell he needed to follow the former Fed chair’s lead and spend more time in Congress than his predecessors Yellen and Bernanke. “The accountability for the Fed runs through Congress,” said Claudia Sahm, a former Fed official who is now chief economist at New Century Advisors. “That’s not just about having people on speed dial — it’s answering questions, explaining policy and getting feedback.” Source: FT Ethiopia’s PM Abiy and Nigerian business tycoon, with Chinese engineering, are driving industrialization in Ogaden/Somali region of Ethiopia. - Michael Masri’s reporting for Africa Report if fascinating. Ethiopia has launched a cluster of large industrial schemes in the Somali region, laying foundation stones for a urea plant and an oil refinery in Gode while opening the first two phases of the Ogaden LNG project. Abiy Ahmed framed the push as part of a broader strategy to link energy, agriculture and industry. “These projects embody more than industrial growth,” he said. “They represent our shared responsibility to harness opportunities, strengthen co-operation and promote peace.” The Gode urea plant, backed by Dangote Group and Ethiopian Investment Holdings (EIH), is designed for 3m tonnes a year. Dangote owns 60%, while EIH holds 40%. Officials say Dangote’s equity totals about $2.5bn, while the state provides land and implementation oversight. Gas from the Calub fields will be piped 108km to the site. Construction is slated for 40 months, with operations targeted for 2028. Ethiopia imports most of its fertiliser, spending more than $1.2bn a year for 1.5m–2m tonnes. Usage was roughly 1.7m tonnes in 2023, almost half of it urea, and demand for 2024–25 is put above 2.4m tonnes. If delivered on time, the Gode plant could cover domestic needs and allow exports to neighbours. Brook Taye, chief executive of EIH, called the venture “a significant milestone in the journey toward industrial self-sufficiency”. Dangote told the groundbreaking crowd that the complex would be integrated with gas supply and a polypropylene unit to support local inputs. He pointed to Ethiopia’s Grand Ethiopian Renaissance Dam (GERD), with a capacity of more than 5,000MW, and noted his group’s cement operations and expansion plans. The Gode refinery is being developed by Golden Concord Group of China. It is designed to process 3.5m tonnes a year of crude and condensate from the Hilala field, with associated storage. Backers say it will ease foreign-exchange pressure from fuel imports and anchor further industrial activity, including a proposed steel smelting site in Dire Dawa. GCL’s chair, Zhu Gongshan, cast the project as “a key step in Ethiopia’s path to energy sovereignty”, underscoring the Beijing–Addis ties. Financing details are still being finalised, but the refinery is central to the government’s energy-security narrative. Source: The Africa Report Dangote’s Ethiopian vision: Dangote began with cement. His crown jewel, Dangote Cement, dominates Nigeria’s market and has 10 operations in other nations in Africa. The formula has been consistent: identify sectors with chronic shortages – cement, fertiliser, sugar – commit massive local investments, and scale up to serve regional demand. Ethiopia was a natural extension of that model. In 2015, Dangote launched the Mugher Cement Plant outside Addis Ababa at a cost of $600m, with an annual capacity of 2.5 million tonnes. The investment gave him a firm foothold in one of Africa’s fastest-growing construction markets. But success came with risks. In May 2018, violent unrest led to the killing of Dangote’s country manager and temporary shutdowns at Mugher. While other investors might have retreated, Dangote doubled down. Today, he is preparing to spend $400m to expand Mugher’s capacity to 5 million tonnes, alongside a new grinding unit near Addis Ababa. Cement is just one market Dangote is targeting. Ethiopia’s enormous state-controlled sugar industry, long plagued by inefficiency and debt, has struggled for years to reform. Its Omo Kuraz Sugar Development Project, touted as one of the continent’s largest initiatives, continues to face delays and mismanagement. … The most ambitious venture of all is the planned fertiliser production complex in Gode, Somali region. Publicised on 28 August 2025, the Dangote Group and Ethiopian Investment Holdings (EIH) deal plans one of the world’s largest single-site urea manufacturing plants. The project costs an estimated $2.5bn and has an estimated capacity of 3 million metric tonnes annually, a rate that would not only render Ethiopia independent, but even a net exporter of fertiliser. EIH, the state wealth fund of Ethiopia, will hold 40%, while 60% is held by Dangote Group. … For Dangote, Ethiopia is a trifecta: Cement demand is projected to grow by 10% annually, its sugar consumption is growing with rapid urbanisation, and fertiliser demand is all but insatiable, given that farming supports the livelihood of 70% of Ethiopians. Source: The Africa Report The stakes for Abiy are high: For Addis Ababa, the $4bn fertiliser project in Ethiopia’s Somali region is no longer simply a manufacturing investment. It is increasingly being framed as a strategic state project tied to food sovereignty, import substitution and the government’s broader attempt to build economic resilience under mounting fiscal pressure. “Becoming self-sufficient in food is our main agenda,” Abiy says during the visit. “Land is needed; we have it. Water is needed; we have it. Human resources are needed; we have it.” The scale is enormous even by African industrial standards. Once operational, the plant is expected to produce three million metric tonnes of urea annually, potentially making it one of the continent’s largest fertiliser complexes. Ethiopian officials say the project now includes a 110km gas pipeline, a 120MW power plant, a polypropylene packaging facility and a two-million-tonne NPK blending plant. For a government grappling with chronic foreign exchange shortages, ballooning import bills and pressure on agricultural productivity, the numbers matter politically as much as they do economically. The decision to anchor the project in Gode is deliberate. Long viewed as peripheral to Ethiopia’s industrial economy, the Somali region is now being repositioned by the federal government as a future irrigation and agro-industrial corridor. Officials argue that the area’s vast land reserves and access to water could eventually support large-scale commercial farming capable of reshaping Ethiopia’s food economy. The government is simultaneously building housing infrastructure for about 5,000 residents near the plant, while officials project broader industrial expansion along the corridor. Abiy goes further, comparing the long-term revenue potential of the Gode development zone with Ethiopia’s flagship state enterprise. “The investments we are making in this Gode area, combined, will generate high revenue for Ethiopia, at par with Ethiopian Airlines,” he says. Source: The Africa Report Feliks Topolski 1907-1982 Topolski’s Chronicle, ‘Nazi Revival’, Vol. 8, Is. 1-2, 1960 HEY READERS, THANK YOU for opening the Chartbook email. I hope it brightens your day. I enjoy putting out the newsletter, but tbh, what keeps this flow going is the generosity of those readers who clicked the subscription button. Photo by Jakub Dziubak on Unsplash If you are persuaded to click, please consider the annual subscription of $50. It is both better value for you and a much better deal for me, as it involves only one credit card charge. Why feed the payments companies if we don’t have to. Subscribe Grim vision of drone warfare by Sylvie Kaufmann For contributing subscribers only. Subscribe The state of the art in Colbert-studies. Jean-Baptiste Colbert was Louis XIV chief minister from 1661 to 1683 and traditionally seen as an architect of absolutism and mercantilism. Alexander Hamilton later cited him as an inspiration in 1782. Now his legacy is disputed. Daniel Dessert, the chief critic, sees Colbert as the orchestrator not so much of an absolutist state as of an elite cabal. Would be great to have a good English-language review of this important debate. Source: lhistoire Didn’t know that the Magna Carta included free trade provisions Fighting for the right to the beach in Oregon in 1967: Source: Research Gate RAF Station – British and Polish Flags, c. 1940-45, The Ingram Collection Feliks Topolski, 1907-1989 ink and wash If you’ve scrolled this far, you know you want to click: Subscribe

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May 25 • 6:23 AM EDT • Politics • adamtooze.substack.com
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How The Sphere Entertainment (SPHR) Investment Story Is Shifting With New Targets And Projects

Analysts have lifted their fair value estimate for Sphere Entertainment from $136.36 to $161.00, pointing to a higher price target in updated models. That shift lines up with a wave of research that includes higher targets, rating upgrades and new coverage as more institutions focus on the company’s project pipeline and potential role in industry deal discussions. As you read on, you will see how to track these changing views and what to watch as the Sphere Entertainment story evolves. Stay...

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May 25 • 12:29 AM EDT • Entertainment • finance.yahoo.com
Box Office: ‘Mandalorian and Grogu’ tops charts and ‘Obsession’ grows in second weekend

Studio estimates on Sunday say “Star Wars: The Mandalorian and Grogu,” has made $82 million in ticket sales in the U.S. and Canada over the weekend.

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May 24 • 11:56 AM EDT • Entertainment • seattletimes.com
Box Office: ‘Mandalorian and Grogu’ tops charts and ‘Obsession’ grows in second weekend

Studio estimates on Sunday say “Star Wars: The Mandalorian and Grogu,” has made $82 million in ticket sales in the U.S. and Canada over the weekend.

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May 24 • 11:55 AM EDT • Entertainment • news4jax.com
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The Atlantic Ocean Was Hiding a Massive Freshwater Reservoir Big Enough to Supply NYC for 800 Years

Scientists have discovered a massive freshwater reservoir buried beneath the Atlantic Ocean, stretching from New Jersey to Maine — and early estimates suggest it could hold enough water to supply New York City for nearly 800 years. Researchers believe the reservoir dates back to the last ice age, though it could take years to determine whether the water can — or should — ever be tapped.

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May 24 • 8:00 AM EDT • Technology • foodandwine.com
Bond breakout? Big effects of bad data. Immigration and thermostatic politics & dad-chat is coming for dad-books.

Thank you for opening your Chartbook email. Anna Airy, A Shell Forge at a National Projectile Factory, Hackney Marshes, London, 1918 Bond breakout - John Authers Across the developed markets, bond markets are staging a slow-motion car wreck. Looking at the drastic moves in the US, Japan, the UK and France, Barclays’ Ajay Rajadhyaksha commented: “Last week, long bonds broke. Not in one country. In all of them. Simultaneously. Four countries. Four different political systems. Four different central banks. But the same trade — “get me out of duration!”” Each country has its own contributing political problems, but the uniformity of the shift out of long-term bonds with high duration makes clear that something broader is afoot. For Rajadhyaksha, it is “simple and uncomfortable.” The developed​ world “has too much debt, too little fiscal discipline, and no political appetite for fixing either.” If there’s a trigger, it has been the Iran war and the resulting shock to oil supply. Source: Bloomberg G7 countries are now borrowing at rates that were enjoyed by EM in the early 2020s For contributing subscribers only. Subscribe Trade between China and Russia has grown in recent years For contributing subscribers only. Subscribe Big effects of bad data A decade ago nearly nine in ten Americans, when approached, agreed to fill out the Current Population Survey, which is administered to about 60,000 households each month and asks about, among other things, employment. Fewer than seven in ten do so now (see chart 1). For the Consumer Expenditure Survey, which tries to capture 3,700 households monthly, the response rate is down from 68% to 40%. … When the information becomes less reliable, investment decisions get more difficult to make. Some may be delayed, creating a potential drag on the economy. A new working paper by Nicholas Bloom of Stanford University, Erica Groshen, former head of the Bureau of Labour Statistics (BLS) now at Cornell University, and Duncan Hobbs and Michael Strain of the American Enterprise Institute, a think-tank, hazards an estimate. Preserving trust in “the integrity and quality of official statistics”, the authors claim, generates economic benefits of about $25 for every $1 spent on the BLS, the agency with an annual budget of $700m that is responsible for many of these data. To arrive at their conclusion the quartet analysed an ignoble episode in the BLS’s recent history. On August 1st 2025 Donald Trump sacked Erika McEntarfer, appointed as the agency’s commissioner by his predecessor, Joe Biden. The president alleged, without evidence, that the BLS’s steep downward revision to recent jobs numbers had been “RIGGED in order to make the Republicans, and ME, look bad”. In fact, it was the wanton dismissal that looked bad in the eyes of many observers. In the following seven days there was a 50% leap, relative to the week before, in the average value of the index of Economic Policy Uncertainty (EPU), which tracks the number of articles mentioning such uncertainty that are published daily in American newspapers. This was a discernible jump even when compared to the chaos caused by Mr Trump’s trade war in April 2025 and his real one in Iran in the past two months (see chart 2). Based on Mr Bloom’s earlier study with other colleagues of the EPU’s impact on business investment, industrial production and employment, the authors estimate that the jump reduced American GDP by over $100bn (0.3%) and non-farm payrolls by 168,000 (0.1%). Source: The Economist Immigration and thermostatic politics (Sarah O’Connor in the FT) A strange thing happened a year and a half ago. No sooner had Americans elected Donald Trump as president on an explicitly anti-immigration platform than US public opinion began to swing much more favourably towards immigration. … to political scientists who study “thermostatic” politics, this development is no surprise at all. Public opinion often moves against the prevailing party, especially if they are perceived to have gone “too far” in one direction. The phenomenon was first explored in the 1990s with reference to fiscal policy, but in recent years it has been particularly evident in the realm of immigration policy. While these swings in opinion polls can make it seem as if people don’t know their own minds, they can be a useful democratic check on governments by sending bright flashing warning lights when policies stray too far from the public’s comfort zone. The problem comes when politicians misinterpret those signals. When people tell pollsters they want less immigration, or think it is bad for the country overall (or the converse), they are often expressing an opinion about how things appear to be going in that moment relative to their preferences, rather than a deep shift in their underlying views. According to Alexander Kustov, a political scientist, most Americans’ views are quite stable and moderate: they support immigration that is controlled and in the national interest, and oppose flows that are disorderly or under-enforced. In the US, he argues the Trump administration over-interpreted dissatisfaction with high immigration under Joe Biden, and implemented policies that went too far for many voters. “People don’t necessarily change their idea about their ideal immigration policy, but they can react to what the government is currently doing,” he told me. “A lot of people are not happy with what the Trump administration are doing — right now we’re not talking about border enforcement, we’re talking about people not just getting harassed, but killed.” But similarly, he added, pro-immigration advocates would be making a mistake to interpret the recent, more favourable swing towards immigration as a deep-seated ideological shift in attitudes. The recent history of UK immigration policy offers another cautionary tale. After the 2016 Brexit referendum, public concern about immigration fell. This was partly because net migration statistics declined, but also because people felt a sense of catharsis and control, says Sunder Katwala, director of British Future, a think-tank. By 2019, the public ranked immigration as only the ninth biggest issue of concern, according to Ipsos polling. But when the Conservative government liberalised visa routes for students and care workers between 2019 and 2022, that helped net migration to surge. And so, too, did public concern. Today’s Labour government has implemented another sharply restrictive turn in immigration policy. As Kustov and researcher Caitlyn Yates argue, thermostatic public opinion should be a useful check on politicians. Instead it seems to have helped to magnify the pendulum swing in the UK. The government over-interprets and overreacts to a change in public opinion, which reacts in turn, prompting a sudden swing the other way. Source: Financial Times HEY READERS, THANK YOU for opening the Chartbook email. I hope it brightens your day. I enjoy putting out the newsletter, but tbh, what keeps this flow going is the generosity of those readers who clicked the subscription button. If you are persuaded to click, please consider the annual subscription of $50. It is both better value for you and a much better deal for me, as it involves only one credit card charge. Why feed the payments companies if we don’t have to. Subscribe Anna Airy, Shop for Machining 15-Inch Shells: Singer Manufacturing Company, Clydebank, Glasgow, 1918 Racing for a vaccine … we have been here before! The deadly Ebola outbreak in two African countries driven by a virus species with no vaccine has triggered an urgent search for a potential jab, in a test of troubled global efforts to avert threats posed by emerging diseases. A World Health Organization advisory group is due to would meet on Tuesday to recommend candidate jabs to prioritise for clinical trials, the global health body said. It will assess data including an analysis by the Coalition for Epidemic Preparedness Innovations (Cepi), which was set up after failures in the international response to a previous Ebola crisis. The latest Ebola outbreak in Democratic Republic of Congo and Uganda has infected hundreds of people and killed more than 80, health authorities say. Cepi’s reaction will be a crucial indicator of its progress towards its wider goal of producing vaccines for pandemic threats in just 100 days, despite steep cuts to international health funding. “If there was ever a time that we could show the world why Cepi is needed and show the world why the 100-day mission is needed, it’s now,” Nicole Lurie, the organisation’s executive director for preparedness and response, told the FT. “We’re happy to accept that responsibility, but obviously we need help from partners — particularly financial help in the long run.” DR Congo and Uganda would make the final decision on whether to press ahead with any vaccine candidates endorsed for clinical trials by the WHO experts, the global health body said. “Other ethical and community acceptability issues will be considered,” said the WHO, which declared the latest outbreak a public health emergency of international concern on Sunday. “This will be important to make sure that the trial, if it happens, will be adequately communicated to the population.” Lurie said Cepi had provided information from a survey of research teams and companies working on drugs that might be effective against the Bundibugyo virus behind the outbreak. The organisation hoped soon to announce partners in the quest for a jab, she added, although she declined to give a timescale for when one might be developed. Cepi’s Nicole Laurie said global health bodies were ‘getting some live-fire drills’ with hantavirus and the latest Ebola outbreak. The hunt for a vaccine should be helped by scientific advances including the use of artificial intelligence to find drugs active against viruses, Lurie said. Existing jabs against the Zaire Ebola virus responsible for many previous outbreaks might provide a basis for tackling the Bundibugyo species, she added. “We’ll see how far and how fast we can get,” Lurie said, adding that Cepi had done preliminary work recently on a possible jab for the rat-borne hantavirus responsible for a recent fatal outbreak on a cruise ship. “Both with hantavirus and now with Ebola, [we] are getting some live-fire drills.” Source: Michael Peel in the Financial Times Dad-chat is coming for dad-books. (By Pamela Paul and Jeffrey A. Trachtenberg in the WSJ) They were the go-to gifts for Father’s Day: a book about some little-known chapter of World War II, the sweeping narrative of a shipwreck, perhaps the latest presidential biography. These days, dad books are a dying breed. Nonfiction book sales have been in decline for the past four years, and are now the most challenged segment of the print book market. Publishers say certain types of books still fare well—including celebrity memoirs and religious titles. But in recent years, print sales in such categories as biography, current affairs and business and economics—what publishers refer to as “serious nonfiction” and which tend to resonate especially with men—have fallen considerably. Sales of nonfiction print titles were down nearly 8% through May 9 this year, and sales of books about politics and current affairs were down 19%, according to book tracker Circana BookScan. Publishing has long been subject to cyclical changes, with trends in format and genre taking over bookshelves in grand sweeps. (Remember the adult coloring-book craze? Or the stratospheric rise of romantasy?) But many in publishing believe the decline in serious nonfiction is more existential. “The trend couldn’t be clearer,” said Jonathan Karp, the former chief executive of Simon & Schuster and publisher of the new Simon Six imprint. “This is a sea change and people should wake up and realize we’re living in a new world.” One culprit for the shift: a new media diet for fans of more serious nonfiction. … Sixty-two percent of men and 54% of women consumed a podcast in the prior month, according to a recent survey by Edison Research at SSRS, up from 46% and 39%, respectively, in 2023. “When we have internal meetings to talk about this problem, it always comes around to podcasts,” said Jonathan Burnham, president and publisher of the Harper Group at HarperCollins Publishers. “The man who wants to read American history is now tuning into one of the many good podcasts about history that lends the quiet attention to a serious subject he’s looking for. It makes the idea of sitting down with a 700-page Ron Chernow book less appealing. You’ve scratched that itch.” Source: Wall Street Journal Remarkable report by Novara from the nationalist rally in London in mid May. Anna Airy, Leopard Moth and Plums, 1915 If you’ve scrolled this far, you know you want to click: Subscribe

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May 23 • 6:45 AM EDT • Politics • adamtooze.substack.com
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Forza Horizon 6 Races Toward Estimated 5M Sales and $325M in Week One Despite Game Pass Cannibalizing Some Sales

Forza Horizon 6 is reportedly nearing 5 million copies sold and $325 million in gross revenue in its first week on store shelves.

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May 22 • 11:36 AM EDT • Technology • wccftech.com
Preserving the future of vaccine science in the USA

Nature Microbiology - Vaccines have saved an estimated 154 million lives in 50 years, yet that infrastructure is under threat. We highlight the global impact of vaccine scientists who trained in...

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May 21 • 8:00 PM EDT • Science • nature.com
Take-Two forecasts annual bookings below estimates, sticks with 'GTA VI' launch timeline

Take-Two Interactive forecast ​annual bookings below Wall Street ‌expectations on Thursday, but reiterated the November 19 launch date for the highly awaited "Grand Theft ​Auto VI," sending its shares ​up around 6% in extended trading.

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May 21 • 4:20 PM EDT • Technology • reuters.com
As losses from scams surge, Congress asks telecoms to do more to prevent them

A powerful congressional committee is urging major telecommunications companies to do more to protect Americans against scams, part of a widening investigation into the role that U.S. companies play in the surge in cyberscams that cost Americans an estimated $200 billion in 2024.

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May 21 • 3:43 PM EDT • Politics • pbs.org
SpaceX Sees a Huge Market for Its Business. Most of It Isn’t Space-Related.

SpaceX said in its IPO filing yesterday that it estimates a “TAM,” or total addressable market—a business term for potential revenue opportunities—of $28.5 trillion. The figure includes: $370 billion in Space from space-enabled solutions and $1.6 trillion in Connectivity, including Starlink Bro

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May 21 • 9:24 AM EDT • Business • wsj.com
Stuck in the hospital? A WA program offers a path to speed recovery, save money

On any given day in Washington, state estimates show nearly 850 patients are medically ready for discharge, but myriad barriers keep them in the hospital.

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May 21 • 9:00 AM EDT • Health • seattletimes.com
Iran rebuilding military industrial base faster than expected, already producing drones, according to US intel

Iran has already restarted some of its drone production during the six-week ceasefire that began in early April, one sign it is rapidly rebuilding certain military capabilities degraded by US-Israeli strikes, according to two sources familiar with US intelligence assessments. Four sources told CNN that US intelligence indicates Iran’s military is reconstituting much faster than initially estimated.

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May 21 • 3:09 AM EDT • Politics • cnn.com
Assessing PEPFAR’s Health Spillover Effects Beyond HIV: An Update

This analysis updates prior work that assessed the association between PEPFAR investments and several health indicators, beyond HIV. It finds that PEPFAR continues to be associated with significant improvement in these broader health gains, suggesting a spillover effect beyond the program's HIV focus.

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May 20 • 10:15 AM EDT • Health • kff.org
Seminole County approved indoor sports complex expected to generate $2.4B

Seminole County commissioners have approved plans for a new indoor sports complex that officials say could generate an estimated $2.4 billion in economic impact over the next 30 years.

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May 19 • 5:40 PM EDT • Sports • wesh.com
Dr. Roach: Man underestimates chewing tobacco's influence on his health

I'm frustrated and worried about his future.

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May 19 • 12:00 AM EDT • Health • detroitnews.com
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Whoa! Netflix is Sending Narnia Heading to Theaters...What This Means for the Future of Film

(Welcome to the “Most Important Story of the Week”, my bi-weekly strategy column analyzing the most important (but often not buzziest) news story of the last two weeks. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. Please subscribe.) Here’s a funny thing about the debate over whether streamers should release their movies in theaters first: Both sides think the other side represents the “conventional wisdom”. If you’ve been reading me for any amount of time, or even just scanned my front page, you know I think movies make more money by having a robust theatrical window compared to going straight-to-streaming. I’ve published thousands of words on this topic. And for years, I felt like I was standing up to a wave of opposition. See, while the “put your films in theaters to make money” take was obvious at any point before 2019, post-streaming revolution, most of the trendy thinkers took the opposite point of view. Big names argued that Netflix putting their film straight-to-streaming (“S-to-S” from here on out) actually made more money. Netflix was “disrupting” theaters, just as they disrupted Blockbuster Video, and since innovation is always good, this too was a great idea. This thinking then leaked into the mainstream business outlets like the Wall Street Journal and Bloomberg. I read many articles whose take boiled down to “Netflix makes tons of money from S-to-S releases” and “theaters were in structural decline” anyways. Covid-19 shutting down theaters and the 2023 strikes shutting down film production seemingly justified this point of view, as the box office struggled to return to 2017-2019 heights. Yet I’ve also read folks arguing the opposite point: the conventional wisdom says to put films in theaters! From some writers’ points of view, “everyone” actually agrees/agreed with my “send your films to theaters” take—especially the stodgy traditional studios—and folks still didn’t understand Netflix’s genius. I feel like, for the last two years, many people have argued this point as if it’s conventional wisdom. You know what? I may have been wrong. At this point, the “S-to-S strategy makes money” might be the minority viewpoint. Especially with the news this month that Netflix will put at least one film—Greta Gerwig’s Narnia film The Magician’s Nephew—in theaters in 2027 for a full 49-day run is big news. So that’s the story of the week, but I’ll also explain why they’re making this move now and why Netflix may not completely embrace theaters, along with other topics, like how I don’t buy Disney’s “super app” strategy, the latest good news out of the unions, my take on the latest attacks against free speech, and a whole lot more. Let’s get started. Subscribe Most Important Story of the Week - Netflix Goes to Theaters! Listen, I promise not to victory lap too hard today. As I just wrote, I’ve argued against sending films straight-to-streaming for—checks calendar—eight years now. Since 2018. Yikes. That’s a long time. And for years, others painted my thinking as “conventional” in that I was standing up for the status quo against trendy, cool disruption. And that’s not cool! But math is math, and I never could make the S-to-S numbers work. The only thing that ever enabled that model was Wall Street’s brief exuberance for it. It seems like the heads of Netflix now agree with me. (There were always rumors that former head of film for Netflix Scott Stuber argued internally for theatrical releases as well.) As they announced: “The Magician’s Nephew_—the first film in a Narnia series of films—will open on 12-Feb-2027, with a 49 day theatrical exclusive run.”_ I’m a little surprised at how little coverage this big change actually got. Credit to Bloomberg for leading with it and Matt Belloni’s The Town for highlighting it with the provocatively titled podcast “Hell Hath Frozen Over”. But after that? Instead of getting as much coverage as, say, the FCC’s latest egregious crackdown on free speech, this news story got crickets. But it’s massively more important for the future business of entertainment. So let’s start with the obvious question… Why Put Your Movies in Theaters? So…why should Netflix put (some!) of their movies in theaters? Well, I’ve already written that in a very, very, very long article from 2022: [ ](https://entertainment.substack.com/p/the-data-is-in-theatrical-films-massively) [ The Data Is In: Theatrical Films Massively Outperform Straight-To-Streaming Films ](https://entertainment.substack.com/p/the-data-is-in-theatrical-films-massively) Entertainment Strategy Guy · April 5, 2023 [ Read full story ](https://entertainment.substack.com/p/the-data-is-in-theatrical-films-massively) To summarize, theatrical runs make much more money, especially blockbusters, because they earn more money per viewing,1 and that helps boost home entertainment sales. Theatrical films also perform as well or better than the streaming-only films. Now, partially this is driven by increased marketing for said films, but said marketing ultimately boosts the awareness of the movies and drives improved streaming and library performance as well. Again, I’ve made this case after reviewing the economic models and streaming data for years. Just last week, Emily Horgan also made the case for kids films! Yes, it is probably conventional wisdom, but that’s also because it’s true! I’d also argue we’ve seen a lot of data in the various studios’ behavior. As I’ve noted before, the more a studio needs to make money, the likelier they are to put films in theaters. As such, Disney, Universal, Warner Bros., Paramount and Sony all send their major films to theaters. Even if they once made a big S-to-S push (*cough* Disney *cough*), they’ve since relented and returned to theaters. The tech companies don’t need to make money, per se, so it took them years to embrace theaters. Apple doesn’t need to make money because it doesn’t disclose their (likely) Quibi-sized losses each year. (They fear bad press more than losing money.) Amazon announced two years ago that they planned to make Amazon-MGM Studios/Prime Video profitable on its own, and guess what? Now they’re putting films in theaters. That leaves Netflix. They’re in between the “no need to make money at all” and the “desperately need to make money to offset linear TV declines”, so they had less pressure to put some films in theaters. Plus, for years, they were the sexy disruptor, and Wall Street rewarded them for that. (Honestly, they still do.) Yet, even Netflix likely saw the money they were leaving on the table (I’ve estimated it at an easy billion dollars before) so they changed their course. I heard one pundit argue that, because Netflix already makes so much money, they don’t need to make more money, which sort of goes against everything I’ve ever learned about business and economics. Again, to be super-nuanced, sending “films to theaters” does not mean EVERY film. TV movies have been a thing for decades. Lifetime films, Hallmark holiday films, Disney Channel Original Movies, and so on, don’t need theatrical runs. But films above a certain budget level (say $25 to 50 million) almost certainly need theaters to maximize their revenue. The Scenarios (with a Dose of Skepticism) Now time for some skepticism: it won’t surprise me at all if Netflix re-changes course. Specifically, Netflix announced that their Narnia film will go to theaters. And I’d bet anything we see KPop Demon Hunters 2: The Huntering2 also goes to theaters, cause it’s the surest hit outside of a Disney animated sequel right now. But how much does Netflix truly commit to theaters? They’ve already tried to emphasize that this is a one-off move. I see three broad scenarios:

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May 18 • 3:27 PM EDT • Entertainment • entertainment.substack.com
THE WEEK OF MAY 18, 2026

- House releases Energy Water bill - Republicans highlight research security concerns - Golden Dome cost estimated at over $1 trillion

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May 18 • 12:39 PM EDT • Science • aip.org
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Could A Simple Lab Mistake Lead Scientists to Over-Estimate Microplastics?

While microplastics are a very real issue, one new study suggests that the numbers might not be quite as bad as we've feared.

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May 18 • 11:30 AM EDT • Science • yahoo.com
Could A Simple Lab Mistake Lead Scientists to Over-Estimate Microplastics?

While microplastics are a very real issue, one new study suggests that the numbers might not be quite as bad as we've feared.

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May 18 • 11:30 AM EDT • Science • extremetech.com
People overestimate how confident AI systems are in their responses, experiments reveal

Artificial intelligence (AI) systems, particularly conversational agents such as ChatGPT or Gemini, are now used daily by a growing number of people worldwide. While many users trust the answers of AI ...

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May 17 • 12:00 PM EDT • Technology • phys.org
‘Michael’ reclaims the top box office spot in its 4th weekend

The Michael Jackson biopic, “Michael,” is reclaiming the top spot in the North American box office. Studio estimates on Sunday show the film earned $26.1 million in its fourth weekend

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May 17 • 11:43 AM EDT • Entertainment • lancasteronline.com
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Whole Hog Politics: Idiocracy alert

It is easy — indeed, too easy — to see the damage that the COVID-19 pandemic and lockdowns did to America’s young people. I say “too easy” because, as the most recent estimates from Stanford University’s Educational...

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May 15 • 4:00 PM EDT • Politics • aei.org
How old do you look? Try this AI tool from Boston researchers

Could a selfie reveal clues about your health and life expectancy? A new AI tool developed by Boston researchers is using facial images to estimate biological age — and NewsCenter 5’s Jessica Brown tested it herself.

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May 14 • 10:14 PM EDT • Health • wcvb.com
Tiny ocean life helps scientists estimate whale prevalence off the California coast

A new approach to better assessing whale population data has emerged, led by a research team of marine biologists from Scripps Institution of Oceanography at UC San Diego and statisticians from Cal Poly. ...

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May 14 • 5:00 PM EDT • Science • phys.org
Essentia Health hosting free heart failure symposium

It’s estimated that more than six million adults in the United States are living with heart failure, according to the Centers for Disease Control and Prevention (CDC).

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May 14 • 11:18 AM EDT • Health • essentiahealth.org
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WEBTOON Entertainment Inc. (NASDAQ:WBTN) Just Released Its First-Quarter Results And Analysts Are Updating Their Estimates

It's been a good week for WEBTOON Entertainment Inc. ( NASDAQ:WBTN ) shareholders, because the company has just...

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May 14 • 9:29 AM EDT • Entertainment • finance.yahoo.com
A new species offers a clue to the boom of giant dinosaurs

Nagatitan chaiyaphumensis may be the largest dinosaur ever found in Southeast Asia. Paleontologists estimate this behemoth weighed 30 tons and measured over 88 feet long.

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May 13 • 8:00 PM EDT • Science • nationalgeographic.com
Gov. Newsom to propose tax cut for new small businesses with May Revise budget

California Gov. Gavin Newsom is set to propose a 50% tax cut for hundreds of thousands of small businesses, as part of his revised budget presentation on Thursday. The proposal to benefit an estimated 250,000 new businesses each year is part of the updated look at Newsom's budget priorities for the upcoming fiscal year, known as the May Revise.

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May 13 • 7:12 PM EDT • Business • kcra.com
Iron Range Science and Engineering Festival provides hands-on learning

CHISHOLM—An estimated 600 kids from 10 school districts across the Range attended the Iron Range Science & Engineering Festival held this week at Minnesota Discovery Center.

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May 13 • 6:30 AM EDT • Science • mesabitribune.com
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How The Investment Story Is Shifting For AMC Entertainment Holdings (AMC)

Analysts have recently adjusted their price targets for AMC Entertainment Holdings, with some referencing fair value estimates around US$2.03 per share and others setting more cautious targets near US$1.10 to US$1.50. These moves reflect a split view, where bullish research relies on revenue and margin assumptions, while bearish reports focus on capital structure and execution risks, especially around box office expectations. As you read on, you will see how these differing calls fit into the...

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May 12 • 5:24 PM EDT • Entertainment • finance.yahoo.com
WATCH: Murray calls Pentagon's Iran war cost estimate 'suspiciously low,' presses for damage price tag
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May 12 • 5:21 PM EDT • Politics • pbs.org
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Bayer Profit Tops Estimates on Strong Crop Science Performance

Bayer AG posted better-than-expected profit in the first quarter, driven by a robust performance in its crop-science unit.

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May 12 • 1:43 AM EDT • Science • bloomberg.com
Inspired Entertainment, Inc. (NASDAQ:INSE) Just Reported And Analysts Have Been Cutting Their Estimates

It's been a pretty great week for Inspired Entertainment, Inc. ( NASDAQ:INSE ) shareholders, with its shares surging...

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May 11 • 10:12 AM EDT • Entertainment • finance.yahoo.com
Antarctica is melting from below and scientists say it’s worse than expected

Scientists have uncovered a hidden Antarctic threat that could accelerate global sea level rise far faster than expected. Deep beneath floating ice shelves, long channels carved into the ice appear to trap warmer ocean water, dramatically speeding up melting from below. Even regions of East Antarctica once considered relatively stable may be far more vulnerable than scientists realized. Researchers warn that current climate models may be missing this dangerous process entirely, meaning future sea level rise could be underestimated.

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May 9 • 8:00 PM EDT • Science • sciencedaily.com
Starz Entertainment Q1 Loss Wider Than Expected, Revenues Fall Y/Y

STRZ posts a wider-than-expected Q1 loss; revenues fall 7.2% YoY and miss estimates, while free cash flow remains positive.

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May 8 • 11:48 AM EDT • Entertainment • finance.yahoo.com
A simple dietary change could lower your blood pressure risk by 30%, study suggests | BBC Science Focus Magazine

An estimated 1.4 billion adults worldwide have high blood pressure, putting them at risk of heart attacks and strokes.

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May 7 • 6:30 PM EDT • Science • sciencefocus.com
Watch: Bridge reporters talk medical debt, health care costs on WJR

An estimated 700,000 Michiganders are saddled with medical debt. Bridge reporters joined WJR in Detroit to discuss.

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May 7 • 2:03 PM EDT • Health • bridgemi.com
Flutter Entertainment’s (NYSE:FLUT) Q1 CY2026 Sales Beat Estimates

Global online betting powerhouse Flutter Entertainment (NASDAQ:FLUT) reported Q1 CY2026 results beating Wall Street’s revenue expectations, with sales up 17....

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May 6 • 5:25 PM EDT • Entertainment • stockstory.org
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GTA 6's development costs estimated to be over $1bn, as Take-Two head admits its an "expensive" endeavour

GTA 6 parent company Take-Two is estimated to have spent between $1bn and $1.5bn on Rockstar's upcoming game.

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May 6 • 10:22 AM EDT • Technology • eurogamer.net
Disney beats estimates in CEO Josh D'Amaro's first earnings report

Disney exceeded Wall Street's estimates in its latest quarter, weeks after a major round of layoffs.

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May 6 • 7:04 AM EDT • Business • businessinsider.com
GTA 6 Estimated to Have Cost Take-Two $1 Billion to $1.5 Billion So Far, CEO Strauss Zelnick Says 'It Was Expensive'

GTA 6 may well be the most expensive video game ever made, with parent company Take-Two estimated to have spent $1 billion to $1.5 billion so far.

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May 6 • 6:50 AM EDT • Technology • ign.com
CVS blows past estimates, hikes outlook as insurance business outperforms

All of the health-care giant's business segments, including its insurer Aetna, its retail pharmacy and health services unit, surpassed expectations.

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May 6 • 6:31 AM EDT • Health • cnbc.com
Opinion | New bill would give Minnesota small businesses $100M after ICE surge

ICE actions have resulted in at least $600 million in lost revenue in Minneapolis-St. Paul alone and an estimated $240 million in wages, business leaders write.

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May 6 • 5:59 AM EDT • Business • startribune.com
AMC Entertainment (NYSE:AMC) Surprises With Strong Q1 CY2026

Theater company AMC Entertainment (NYSE:AMC) beat Wall Street’s revenue expectations in Q1 CY2026, with sales up 21.2% year on year to $1.05 billion. Its non-GAAP loss of $0.36 per share was 6.9% below analysts’ consensus estimates.

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May 5 • 5:16 PM EDT • Entertainment • finance.yahoo.com
White House says Trump's deals with pharmaceutical companies offer billions in savings

WASHINGTON (AP) — White House economists estimate that President Donald Trump’s deals with pharmaceutical companies to drop some of their U.S. prescription drug prices to what they charge in other countries could save $529 billion over the next 10 years. The analysis obtained by The Associated Press includes the first economy-wide projections behind a policy at the core of Trump’s pitch to voters going into November’s midterm elections for control of the House and Senate.

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May 5 • 2:15 PM EDT • Politics • pbs.org
A Look At Tencent Music Entertainment Group (TME) Valuation As Analyst Concerns And Dividend Move Draw Focus

Analyst Concerns and Dividend Move Put Tencent Music in Focus Recent analyst downgrades and slightly reduced fair value estimates have pushed Tencent Music Entertainment Group (TME) into the spotlight, as competition and earnings visibility stay front of mind for investors. At the same time, the company’s ordinary annual cash dividend of US$0.12 per share for 2025, with an ex dividend date of 1 April 2026, offers a degree of income continuity that some shareholders may welcome. See our latest...

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May 5 • 4:25 AM EDT • Entertainment • simplywall.st
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Tyson Foods profit beats estimates on strength in chicken business

Tyson ​Foods reported better-than-expected quarterly earnings on Monday, as rising chicken sales ‌helped counter a sharp drop in demand for high-priced beef.

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May 4 • 7:32 AM EDT • Business • reuters.com
Global Health & WASH: May 2026 Funding Opportunities (14 new opportunities!)

The May update for Global Health & WASH brings new calls that cluster around three distinct shifts: LMIC research leadership moving from funder encouragement into a hard eligibility constraint, pharmaceutical and corporate-linked funders running structurally independent education and use-inspired research portfolios at substantial scale, and AI adoption shifting decisively from speculative tool to operational capability across health and WASH systems alike. In LMIC Research Leadership as Eligibility, Not Encouragement, Wellcome anchors the dominant signal of the month with three separate major calls that all require or strongly center LMIC leadership in their basic eligibility architecture. Wellcome’s ESIC Hubs (£1.5-£1.9M per hub over 3-5 years) explicitly requires an LMIC-based lead applicant, treating Global South leadership as a design constraint rather than a participation goal. Wellcome’s Infectious Disease Clinical Trial Development Award funds transdisciplinary teams whose lead must be a mid-career or established researcher based at an organization in Africa, South Asia, or Southeast Asia. Wellcome’s larger Infectious Disease Clinical Trial Award (£1M-£8M for optimizing licensed interventions) requires the administering organization to be in eligible LMIC regions and at least 50% of applicants based there. Around Wellcome, the same pattern shows up at smaller scale and across funders: CHINNOVA channels $1M into West and Central African research institutions for climate-health work; IBRO’s Neuroscience Training Grants explicitly tier ceilings by region of residence with Africa receiving the highest amount ($5,000); IHME’s GBD Emerging Researcher Award reserves at least one of its two annual awards for an LMIC researcher; Sidaction’s HIV Cure call funds research teams across France, the Netherlands, and eligible African countries with a minimum two-country collaboration requirement. Taken together, these calls signal a meaningful shift in how research equity is being operationalized — not as encouragement language at the bottom of a call, but as a structural feature of who can lead, where the work must be administered, and what proportion of the team must be regionally rooted. In Pharma-Funded Independent Medical Education and Use-Inspired Research, the lineup this month is unusually deep. Pfizer alone runs four parallel calls under independent education and quality improvement frameworks: a Migraine and Women’s Health RFP (200K x 2-year, $500K pool), Migraine IME ($200K, $1M pool), JAK Inhibitor evidence-based education ($100K), and Maternal Vaccination HCP Education in Saudi Arabia ($75K), plus a separate Pediatric Pneumococcal Surveillance research call in Saudi Arabia ($400K per project). Novo Nordisk Foundation runs four parallel calls of its own at substantial scale: Infectious Diseases Catalyst Grants (DKK 60M pool, up to DKK 7M collaborative), Non-Diabetic Endocrinology Collaborative Grants (DKK 53M pool, DKK 5-10M per project), Pioneer Innovator Grant Health (DKK 1.1M), and Distinguished Innovator Grant Health (DKK 6.8M). LEO Foundation deploys DKK 2-4M per project for dermatology research excellence. Pfizer’s framing across calls deliberately separates the funding from product promotion, emphasizing measurable practice-relevant change and structural distance between scientific outputs and commercial activity. Novo Nordisk’s “use-inspired” hard filter pushes researchers toward a credible translation pathway from mechanism to deployable tool. The pattern: industry-aligned funders are running structurally independent portfolios at meaningful $ that fund implementation evidence, not promotion. In AI as Operational Capability, Not Speculation, several calls this month explicitly treat AI adoption as a near-term operational question with real evidence and governance requirements, rather than a speculative trend to be watched. Wellcome’s ESIC Hubs frames AI as “the accelerator” for evidence synthesis, asking hubs to translate technical innovation into adoption-ready workflows that can match real-world policy timelines. UNICEF Venture Fund’s new Climate Tech for Children’s Health call funds for-profit startups deploying AI, machine learning, and blockchain in low-resource environments, with a strict requirement that solutions must already have a working prototype with promising pilot results. The Water Research Foundation has launched two simultaneous AI calls treating reproducibility, cybersecurity guardrails, and human-in-the-loop deployments as core design constraints rather than nice-to-haves: one on GenAI and Agentic AI in water utilities ($200K), one on alternatives to water shutoffs that explicitly screens for implementation economics evidence. Nordic Innovation’s quantum technology call (NOK 4.5M) extends the same logic into life science and healthcare, demanding consortium-stage projects mature enough to test with real users. TEF-Health offers €300K in subsidized testing infrastructure for European healthcare AI and robotics SMEs. The pattern: funders are converting AI pilots into playbooks, requiring transfer evidence and risk controls before AI can move from experimentation to sector-wide operational practice. For LMIC-based researchers in infectious disease or evidence synthesis, the three Wellcome calls together represent the deepest concentration of LMIC-led research capital in recent memory — pair the Infectious Disease Clinical Trial Development Award (£200K, deadline May 19) as a strategic pipeline feeder into the larger Infectious Disease Clinical Trial Award (£1-£8M, deadline June 2), since the development award functions explicitly as a track into the larger trial scheme. For Nordic researchers, the four Novo Nordisk Foundation calls plus LEO Foundation and Nordic Innovation Quantum represent ~$30M in regional research capital this cycle, all with deadlines clustered in May-August. For WASH practitioners, the three Water Research Foundation calls together (each up to $200K) are a cluster worth reading across — one on AI deployment, one on shutoff alternatives, one rewarding applied innovation — and the strongest applicants will articulate how their work bridges utility operations to policy-relevant evidence. For US-based clinical researchers and educators, the four Pfizer calls plus the APF Portfolio’s 80+ programs form an unusually accessible recurring pipeline; APF’s prohibition on indirect costs is a meaningful structural feature for early-career applicants whose institutions might otherwise absorb significant overhead. Snapshot of New Opportunities Total Estimated Funding Pool: $100 Million+ USD The grants are organized into three categories: Open Calls: Current grant and opportunities with a deadline. Grants are listed by closing date. 39 open opportunities- 14 new! Rolling Applications: current grant and opportunities with rolling applications (but it’s still best to submit as early as possible). 14 rolling opportunities- 1 new opportunity! Long term planning: Grants that have closed their current rounds, but are expected to open new windows. 4 long term opportunities! A quick tip for returning readers: if you want to jump straight to the newest additions, use CTRL F to search for “New!” and navigate quickly to the latest funding opportunities This post is for paid subscribers. This helps support the time and effort it takes to curate and organize these opportunities. Subscribe To keep this accessible to everyone who needs it, we’re happy to offer pay what you can rates. You can find more details here. Open Calls: Migraine Competitive Grant Program: Migraine and Women’s Health (Quality Improvement and/or Research RFP), Pfizer.*Closing soon!* Pfizer, in collaboration with the American Headache Society, is seeking independent quality improvement and research projects that close persistent gaps in migraine care for women across the United States. The funding logic centers on measurable, practice-relevant change: proposals should generate actionable evidence, tools, or system improvements that can be shared and used widely, not just within a single site. Priority areas span menstrual migraine and screening in women’s health settings, the role of hormonal fluctuations across the lifespan, sex-specific risk factors, comorbidities and quality-of-life burden, and disparities in outcomes by race, ethnicity, and socioeconomic status. The call is structured as a two-step competitive process with an initial Letter of Intent, with the strongest concepts expected to translate scientific insight into implementable improvements in diagnosis, management, and equity. Geographies: United States. Who can apply: U.S.-based organizations (not individuals), including professional schools, healthcare institutions, professional organizations, and other entities focused on healthcare improvement. Funding amount: Up to USD $200,000 total over 2 years; total pool USD $500,000. Targeted Sectors / SDGs: Health; Focus areas: migraine, women’s health, quality improvement, clinical research, menstrual migraine, health disparities. Deadline: LOI: May 5, 2026; Full proposal (by invitation): August 28, 2026. Learn more and apply here. This RFP rewards “shareable impact”: the most competitive submissions will pair rigorous methods with a clear plan for system uptake and dissemination beyond the originating institution. ReSSARC: Strengthening the Health Sector and Food Security in the Central African Republic (AID 013381/01/0) Call for Proposals, Italian Agency for Development Cooperation (AICS). *Closing soon!* AICS is seeking a limited set of high-capacity humanitarian partners to deliver an integrated package that stabilizes essential health services while reducing acute malnutrition and strengthening food security resilience in priority areas of the Central African Republic. The funder’s logic is explicitly nexus-based: proposals should meet urgent, life-saving needs while reinforcing local systems, coordination mechanisms, and community-level capacity so results persist beyond the emergency window. AICS emphasizes inclusion and protection outcomes, expecting gender-sensitive design and explicit measures for groups facing compounded vulnerability, including women, children under five, internally displaced people, and people with disabilities. The call also signals a localization pathway, encouraging stronger collaboration with national NGOs and balanced partnerships, alongside clear coordination with existing cluster and humanitarian actors to minimize duplication and improve coverage. Geographies: Central African Republic (Bangui, Ombella-Mpoko, Ouham, Ouham-Pende, Lim-Pende, Lobaye). Who can apply: Non-profit organizations registered with AICS, plus eligible non-profits without an office in Italy that have a pre-existing collaboration agreement with an AICS-listed organization. Funding amount: Total pool EUR €1,800,000; max EUR €800,000 (single applicant) or EUR €1,000,000 (ATS). Targeted Sectors / SDGs: Health; Focus areas: malnutrition prevention and treatment, maternal and child health, community health services, food security and resilience, localization partnerships Deadline: May 5, 2026. Learn more and apply here. This call is structured to reward partners who can link frontline service delivery to system durability and localization, not just short-term coverage gains. Contracts for Innovation in drug and alcohol addiction healthcare, Innovate UK. *Closing soon!* Innovate UK, on behalf of the Office for Life Sciences Addiction Healthcare Goals program, is procuring R&D to accelerate innovations that can improve treatment outcomes, strengthen recovery, and reduce harm and deaths linked to drug and alcohol addiction. The competition is positioned as a market-facing readiness push: selected projects are expected to advance solutions toward later-stage validation, generate evidence of user acceptability and UK market fit, and map credible routes through regulatory and certification requirements. Innovate UK signals a preference for innovations that can be field-tested in relevant UK settings and progressed to TRL 6 or 7, with practical plans for commercialization after contract completion. This structure favors applicants that can execute most work in-house, co-develop with service providers and people with lived experience, and translate technical progress into deployable tools for addiction healthcare delivery. Geographies: United Kingdom. Who can apply: Single organizations of any size (including EU, EEA, or international) leading delivery, with most work and key deliverables carried out in the UK; subcontractors for specialist skills only. Funding amount: GBP £200,000–1.5 million per project (inclusive of VAT); Total pool: GBP £20 million (across two strands). Targeted Sectors / SDGs: Health; Focus areas: Mental Health, Health Systems Strengthening, Research & Development, Technology Access. Deadline: May 6, 2026 (11:00am). Learn more and apply here. This call uses procurement to pull near-market addiction innovations toward operational proof and adoption pathways in UK services.

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May 4 • 3:59 AM EDT • Health • impactfunding.substack.com
National Australia Bank's first-half cash earnings miss estimate

National Australia Bank reported weaker-than-expected first-half cash ​earnings on Monday as a higher ‌credit impairment charge and a charge related to its software capitalisation policy offset robust ​growth in business lending volume.

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May 3 • 7:09 PM EDT • Business • reuters.com
How The Tencent Music Entertainment Group (TME) Narrative Is Shifting With Mixed Analyst Signals

Tencent Music Entertainment Group’s fair value estimate has been trimmed slightly to US$17.59 from US$17.98, a small reset that keeps the overall framework intact while adjusting assumptions. That move sits against a mixed wave of analyst calls, where several downgrades and price target cuts are balanced by an upgrade to Buy with a US$17.40 target. This reflects competing views around competition, earnings visibility and the recent share pullback. Read on to see what is driving this split...

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May 3 • 7:08 AM EDT • Entertainment • finance.yahoo.com
Curing U.S. Health Care, Part II

On March 23, 2010 President Barack Obama signed the Patient Protection and Affordable Care Act — usually referred to either as the Affordable Care Act or as Obamacare — into law. Joe Biden, then the vice president, could be overheard whispering “This is a big fucking deal.” And it was. The ACA, which went into full effect in 2014, created a system of subsidies and regulations designed to make health insurance available to many Americans who had previously been left out. It worked: In 2010 there were 47 million uninsured people in America, but by 2016 this number had dropped to 27 million. This still fell short of the universal health insurance that every other advanced nation has, but it was real progress. In 2017, during his first term, Donald Trump tried to destroy the ACA, replacing it with the American Health Care Act — legislation that would have eliminated most of the provisions that expanded health insurance under Obama. At the time the Congressional Budget Office projected that the G.O.P.’s replacement bill would nearly double the number of Americans without health insurance, increasing the total uninsured population by 23 million and undoing all of the progress achieved under the ACA. However, the attack on Obamacare failed by one vote in the Senate, and the ensuing public backlash against the G.O.P. delivered a large victory in the 2018 midterms to the Democrats. After these developments many observers assumed that the ACA had become a more or less permanent feature of American life. Such assessments, however, failed to take into account the deep hostility of the U.S. right toward policies that expand access to healthcare. As we’ll see, this hostility goes back generations. And the second Trump administration has taken actions that the CBO projects will add 16 million people to the rolls of the uninsured by 2034. How did we get here? And now what? Today’s primer will analyze the political economy of U.S. healthcare since the 1940s and the combination of danger and opportunity created by the current crisis. Beyond the paywall I will discuss the following: US health care on the eve of Trump II 80 years of US health politics The Obamacare story The new assault on healthcare

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May 3 • 6:31 AM EDT • Health • paulkrugman.substack.com
New York Road Runners Mindful 5K focuses on mental health awareness

Over 6,000 adult athletes and hundreds of youths are estimated to participate in today's New York Road Runners Mindful 5K.

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May 2 • 11:31 AM EDT • Health • abc7ny.com
Op/Ed: North Carolina childcare is in crisis - and a business issue

A full-blown childcare crisis in North Carolina has the full attention of business leaders. It has to. The crisis is costing our state an estimated $5.65 billion every year.

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May 1 • 11:05 AM EDT • Business • businessnc.com
Microsoft earnings top Q3 estimates, says AI business up 123% year over year

Microsoft reported its third quarter earnings after the bell Wednesday.

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Apr 30 • 10:02 AM EDT • Business • finance.yahoo.com
Pentagon’s $25 billion cost estimate for Iran war is low and does not include cost of rebuilding US bases, sources say

The $25 billion estimate that a top Pentagon official gave to lawmakers on Wednesday for the total cost to date of the Iran war is a lowball figure that does not include the cost of repairing extensive damage suffered by US bases in the region, three people familiar with the matter told CNN.

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Apr 29 • 8:17 PM EDT • Politics • cnn.com
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Scientists Rethink How Much Lifespan Is in Our Control

Research upending long-held estimates of genetic influence on lifespan could relieve the pressure to get all the lifestyle factors right.

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Apr 29 • 8:00 PM EDT • Science • medscape.com
MGM Resorts' quarterly profit misses estimates amid slower Las Vegas business

MGM Resorts International missed Wall Street expectations for first-quarter profit on Thursday, hurt by ​weaker performance of its Las Vegas businesses amid ongoing macroeconomic ‌uncertainty.

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Apr 29 • 5:35 PM EDT • Business • reuters.com
Mattel raises annual profit forecast on steady toy demand, entertainment push

Mattel raised its annual profit forecast and beat analysts' estimates for quarterly sales on Wednesday, benefiting from resilient demand for toys and growth in ​its entertainment business.

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Apr 29 • 4:14 PM EDT • Entertainment • reuters.com
Mattel raises annual profit forecast on steady toy demand, entertainment push

Mattel raised its annual profit forecast and beat analysts' estimates for quarterly sales on Wednesday, benefiting from resilient demand for ‌toys and growth in its entertainment business. "We continued to make progress on our strategy to ‌grow our IP-driven play and ⁠family entertainment business and are seeing top-line acceleration in the second quarter to date," CEO Ynon Kreiz said in a statement. Mattel's first-quarter net sales of $862.2 million ‌beat analysts' estimates of $804.7 million, according to data compiled by LSEG.

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Apr 29 • 4:14 PM EDT • Entertainment • finance.yahoo.com
Microsoft tops Q3 estimates, says AI business up 123% year over year

Microsoft reported its third quarter earnings after the bell Wednesday.

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Apr 29 • 4:09 PM EDT • Business • finance.yahoo.com
50-foot ancient snake discovered in India may be one of the largest ever

A massive prehistoric snake discovered in India may rank among the largest ever to slither across Earth. Named Vasuki indicus, this ancient giant lived around 47 million years ago and is estimated to have stretched an astonishing 11 to 15 meters long—rivaling the legendary Titanoboa. Fossilized vertebrae unearthed from a lignite mine in Gujarat reveal a thick-bodied, powerful snake likely built for slow, stealthy ambush attacks, similar to modern anacondas.

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Apr 28 • 8:00 PM EDT • Science • sciencedaily.com
Anthropic doubles estimate for Claude Code token spend

Anthropic now says that the average cost per developer per active day is $13, up from $6 earlier this month.

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Apr 28 • 6:01 PM EDT • Business • businessinsider.com
Gov. Pritzker Cuts Ribbon at SCHEELS Sports Park

New facility will attract an estimated $25 million in annual economic activity, draw 250,000 visitors, and boost Springfield’s tourism economy

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Apr 28 • 2:22 PM EDT • Sports • gov-pritzker-newsroom.prezly.com
South Carolina's measles outbreak is over after sickening nearly 1,000 people

On Sunday, the state passed the threshold of 42 days with no new outbreak-related cases. State health officials estimate the outbreak response cost $2.1 million.

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Apr 28 • 12:57 PM EDT • Health • pbs.org
AMC Entertainment (AMC) Expected to Beat Earnings Estimates: Should You Buy?

AMC Entertainment (AMC) possesses the right combination of the two key ingredients for a likely earnings beat in its upcoming report. Get prepared with the key expectations.

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Apr 28 • 10:00 AM EDT • Entertainment • finance.yahoo.com
Corning faces consumer electronics drag even as data-center business booms

Corning forecast second-quarter revenue below Wall Street estimates on Tuesday, as weakness in the consumer electronics market continues to pressure business ​despite strong demand for data center products.

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Apr 28 • 8:53 AM EDT • Business • reuters.com
‘Michael’ moonwalks to $97 million opening, shattering record for music biopics

“Michael,” the big-budget Michael Jackson spectacle, shrugged off bad reviews and a troubled production to launch with $97 million in U.S. and Canada theaters, according to studio estimates Sunday, shattering a record debut for music biopics.

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Apr 26 • 11:34 AM EDT • Entertainment • seattletimes.com
'Michael' moonwalks to $97 million opening, shattering record for music biopics

“Michael,” the big-budget Michael Jackson spectacle, shrugged off bad reviews and a troubled production to launch with $97 million in U.S. and Canada theaters, according to studio estimates Sunday, shattering a record debut for music biopics | WBBM Newsradio 780 AM & 105.9 FM

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Apr 26 • 11:33 AM EDT • Entertainment • audacy.com