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After school programming, birthday parties and day camps at Brooklyn Science Spot in Carroll Gardens (sponsored) | Brooklyn Bridge Parents - News, Events and Family Services
Brooklyn families, get ready for a fall experience that goes beyond worksheets, screen time, and ordinary after-school programs and camps. At Brooklyn Science Spot, we are opening the door to a whole new way for children to learn, explore, and fall in love with science through hands-on discovery, creative thinking, and real-world STEM fun. Opening
Mary McNamara: As David Ellison names his new empire Skydance, the message is clear: He owns Hollywood
LOS ANGELES — What a surprise. David Ellison has decided to name the Frankenstudio media company created by the merger of Paramount Skydance and Warner Bros. Discovery simply Skydance. And
Rockstar Explains How It Actually Makes A Game Like GTA 6
Working on one chunk at a time, for years and years and years, apparently
New Regulations Make It Easier to Find, Compare, and Report Healthcare Pricing and Coverage Information
HHS announced that Americans will have access to more reliable, accessible, and actionable information about their health coverage
EU Screening Week 2026: Healthy Lungs for Life activities took lung health checks to communities across Europe
The European Lung Foundation (ELF), European Respiratory Society (ERS) and health partners across Europe ran Healthy Lungs for Life events to take part in the first-ever EU Screening Week, a European Commission initiative that promotes prevention, early detection and health education.
OPINION: Pay for performance, not for politics
The North Carolina General Assembly approved substantial pay increases for public schoolteachers earlier this year. If a bipartisan commission has its way, teacher compensation will soar over …
Traders Purchase Large Volume of Call Options on Sphere Entertainment (NYSE:SPHR)
Sphere Entertainment Co. (NYSE:SPHR - Get Free Report) saw unusually large options trading activity on Monday. Traders bought 9,775 call options on the company. This represents an increase of 1,615% compared to the typical volume of 570 call options.
1 person in Hamilton County infected with West Nile virus, health department says
One person has been diagnosed with contracting West Nile virus, the first confirmed case in Hamilton County in 2026.
Business in brief: Oct. 5, 2026
Weekly news and notes from the Henrico business community. Better Business Bureau serving Central Virginia, headquartered in Glen Allen, has begun continuously monitoring licenses and regulatory credentials of its accredited businesses through a partnership with Branvio Inc. BBB said the system replaces repeated manual database checks and has freed more
National Museum of Natural History’s Sant Director Kirk Johnson To Depart for the Denver Museum of Nature and Science
Kirk Johnson announced today that he will step down as the Sant Director of the Smithsonian’s National Museum of Natural History after 14 years in the role, as he prepares to join the Denver Museum of Nature and Science as its next president and CEO. An advocate for science, nature and the power of museums to influence the […]
Trump health officials hold make announcement on healthcare price transparency
Watch as Trump health officials hold make announcement on healthcare price transparency.
Alexandria Health Department no longer offering free COVID-19, flu tests
The department is providing flu shots only to uninsured residents and has issued guidance for the respiratory virus season
Offensive Line Looks Offensive: Spartans Rank Last in Sacks Allowed
From personnel shifts to coaching failures, a crumbling front wall has left the Spartans reeling as record-breaking sack numbers threaten to derail the Pat Fitzgerald era.
Reba McEntire, Ella Langley, Kelsea Ballerini will perform at Dolly tribute
ABC's Dolly Parton tribute unites music's biggest names, from Carrie Underwood to Vince Gill. Here's how to get tickets.
The Legend of Zelda: Master Collection Officially Announced
A partnership between Nintendo and Panini offers a new opportunity for collectors and fans.
Senate Unanimously Passes the Health Care Cybersecurity and Resiliency Act
A bipartisan bill that seeks to improve healthcare cybersecurity and resilience has been unanimously passed by the U.S. Senate. The bill - The Health Care The U.S. Senate has voted unanimously to advance the Health Care Cybersecurity and Resiliency Act, which requires more robust cybersecurity measures for healthcare organizations and authorizes grants to help rural and under-resourced providers improve cybersecurity.
Governor Ivey Proclaims Alabama Girls in Sports Day -
MONTGOMERY – Governor Kay Ivey on Monday proclaimed Saturday, October 10, 2026, as Alabama Girls in Sports Day, recognizing the female athletes throughout the state and reaffirming Alabama’s commitment to ensuring women and girls have the right to participate, compete … Continued
Permits issued for $22 million Perkins Road elementary school, new Southern Classic Chicken location
Here is a list of commercial and residential building permits issued by East Baton Rouge Parish Government from Sept. 28-Oct. 2.
Answering Your Questions as Padres Near Disastrous End to Season
The San Diego Padres are inches away from total collapse, digging themselves into an 0-2 hole against the Milwaukee Brewers. They'll now turn home to a raucous Petco Park crowd with the hopes that they can stave off execution. The postseason allows for some insane turns of fortune. Could the Friars be the next recipient …
CARTI encourages women to prioritize breast health
As part of its annual breast health campaign, CARTI Cancer Center shared critical information regarding the importance of early detection and debunked common misconceptions about breast cancer risk…
Top crypto group to pour millions into bipartisan slate of House races after key legislation stalls
WASHINGTON (AP) — A top cryptocurrency campaign organization is unveiling a bipartisan list of House members that it will support in the November midterms, as o
2026 Outstanding Women in Business
The 18th annual Outstanding Women in Business awards recognize a dozen well-accomplished professionals from across the region and in many industries who go above and beyond. The committee selected the winners from more than 80 nominations, all of whom were worthy. The criteria evaluated each nominee’s professional achievements, community impact, ability to break the glass ceiling and mentorship of other professionals, particularly women. In addition to profiling these women in the following pages, the Worcester Business Journal will celebrate this year’s Outstanding Women in Business at a special luncheon on Oct. 28 at the College of the Holy Cross. To join the celebration of these exceptional women, visit WBJournal.com and register. – Mark Conti, editor This Year’s Judges Worcester Business Journal considered 54 Central Massachusetts professionals for the 2026 Outstanding Women in Business awards, based on 83 nominations. These nominees were independently evaluated by two volunteer judges, who scored each on their professional achievements, community contribution and mentorship of young professionals. Samantha P. McDonald is a partner at Bowditch. She is an experienced, client-focused real estate lawyer, concentrating on business and real estate property law. She has been recognized as a WBJ Power 100 in the Class of 2026 and a “Top Women of Law” in Massachusetts Lawyers Weekly. Dr. Kavita Babu is chief medical officer and vice president of medical affairs at Heywood Healthcare, where she provides strategic and clinical leadership to advance high-quality, patient-centered care across the organization. She is also a member of the WBJ Outstanding Women in Business Class of 2025.
Apple's Newest Macs Just Got Their Biggest Price Cuts Yet on Amazon
Prime Big Deal Days sales are already starting, and have now hit Apple's brand new Mac mini and Mac Studio computers. You can get up to $199 off these 2026 devices with Amazon's latest savings. Note: MacRumors is an affiliate partner with some of these vendors. When you click a link and make a purchase, we may receive a small payment, which helps us keep the site running.
Hellblade studio Ninja Theory has started laying off staff, following Xbox’s announcement that it faces closure
Two separate agreements with the studio “fell through”…
Jeffries says House Democrats aiming to repeat 2018 sweep by flipping Trump districts
The Democratic Party is working to expand the map by going on offense in Republican-held districts, while President Donald Trump hits the trail in a red-state sprint to boost voter enthusiasm and shore up support from his base.
Democrats project a party milestone in Congress: 100 women in the House
Democrats are projecting they could have as many as 113 women in their ranks next year.
John Ternus writes post celebrating Steve Jobs on anniversary of passing
Apple CEO John Ternus and former CEO Tim Cook have shared posts in remembrance of Steve Jobs today on the 15th anniversary of his passing.
Walmsley hopeful Grand Final role leads to new club
Departing Wakefield winger Lachlan Walmsley hopes his starring role in their Grand Final win over Warrington can help him pick up a new team.
Flathead City-County Health Department to hold annual flu clinic
The Flathead City-County Health Department will hold its annual flu clinic Wednesday, Oct. 7, at the Flathead County Fairgrounds Expo Building.The clinic will r
Skydance Executive Team Set By David Ellison Ahead of Deal Close
Skydance announced the executive leadership for the combined Paramount-Warner Bros. Discovery.
Neighborhood Intelligence Provides Business Update and Announces $45.5 Million Equity Financing with Participation from Management and a Single Institutional Investor
NASHVILLE, Tenn., October 05, 2026--Neighborhood Intelligence (NASDAQ: NXH) ("Neighborhood" or the "Company") today announced that it has entered into a definitive agreement for the purchase and sale of an aggregate of 16,485,508 shares of its common stock (or pre-funded warrants in lieu thereof) at a purchase price of $2.76 per share (or pre-funded warrant in lieu thereof) in a registered direct offering. In addition, the Company will issue warrants to purchase up to 16,123,189 shares of common
Apple Watch Prime Day Deals Arrive With New All-Time Low Prices for Series 12 and Ultra 4
Big Apple Watch discounts have started arriving ahead of Prime Big Deal Days, including new low prices on Apple Watch Series 12 and Apple Watch Ultra 4. These deals join some Apple Watch SE 3 discounts that we began tracking over the weekend, alongside other major early Prime Big Deal Days markdowns. Note: MacRumors is an affiliate partner with Amazon. When you click a link and make a purchase, we may receive a small payment, which helps us keep the site running.
Conference to Explore Alternatives to Coercive Mental Health Care
The 18th annual Critical Voices Network Ireland (CVNI) conference will take place at University College Cork November 12 and 13, bringing together speakers and participants to explore critical and alternative responses to human distress.
Is CBIZ (CBZ) Outperforming Other Business Services Stocks This Year?
Here is how CBIZ (CBZ) and GigaCloud Technology Inc. (GCT) have performed compared to their sector so far this year.
Eyes on Growth: TD Survey Finds Small Businesses Confident About Growth Despite Economic Headwinds and Delayed Investments
TD Bank U.S. survey finds 85% of small business owners expect stronger revenue through year-end, despite economic uncertainty and preparedness gaps.
Astronomers say they’ve spotted the first miniature quasar pointed at Earth
Microblazars — a miniature version of blazars — may be responsible for mysterious ultra-high-energy particles.
Bluevine and Coverdash Partner to Bring Embedded Business Insurance to Small Businesses
/PRNewswire/ -- Bluevine, the largest small business banking platform in the US* and Coverdash, a leading embedded business insurance provider powering...
Column: Becerra on cruise control, Hilton offers contrived fixes for California's problems
Look, Xavier Becerra could cruise to a South Pacific island and bask on the beach until election day and Californians would still choose him as their next governor.
Watch live: RFK Jr., Trump officials unveil health care price transparency push
Health and Human Services Secretary Robert F. Kennedy Jr. and Centers for Medicare and Medicaid Services Administrator Dr. Mehmet Oz will announce new efforts Monday aimed at strengthening health c…
Health Brief: Exclusive | Inside the new health price transparency rules
Plus: Trump’s checks to Medicare enrollees could complicate year-end health care negotiations,
Digital Science appoints Charlesworth as strategic sales partner of Altmetric and Dimensions in China’s scholarly publishing sector
Digital Science has appointed Charlesworth as its strategic sales partner of Altmetric and Dimensions in China’s scholarly publishing sector. This collaboration aims to support the growing demand for research data and information across this rapidly developing market.
Datavant, ID.me partner on digital identity verification for medical records
Datavant is partnering with identity verification company ID.me to help patients request their medical records faster and more easily via simple digital credentials. | Datavant has teamed up with ID.me to streamline medical records requests, enabling patients to verify their identities digitally and access records faster.
'Chicago Fire' Season 15 cast – Who's back, exiting amid premiere
Prepare to see some changes when "Chicago Fire" returns this week. The NBC series will see multiple exits amid its 15th season, set to premiere Oct. 7.
Cal-Maine cracks open new growth opportunities
Earnings plunge amid low egg prices and investments in prepared foods.
Why plugged-in pickle glows: Engineer burns 100-plus pickles to find answer
An engineer says glowing pickles owe their orange light to sparks igniting hydrogen near an electrode, with sodium ions supplying the color.
Heartland Catfish Unveils New Website
Heartland Catfish Company recently launched a new website in celebration of its 30th anniversary. The site has been refreshed to focus on retail and food service partnerships, give a detailed look at the company’s products and processes and emphasize consumer education about the benefits of U.S. Farm-Raised Catfish as a versatile and healthy protein source. […]
Ohio Democrats’ path to the governor’s office runs through rural areas that had turned against them
Democrats say their nominee for governor in Ohio, Dr. Amy Acton, represents the party’s best chance in years to win that office.
Ohio Democrats’ path to the governor’s office runs through rural areas that had turned against them
Democrats say their nominee for governor in Ohio, Dr. Amy Acton, represents the party’s best chance in years to win that office.
Buck Motorsports Park & Entertainment Complex
The Buck Motorsports Park is a motorsports entertainment facility located in Quarryville (Buck), Pennsylvania.
Delta Health Center Receives Funding
Delta Health Center, Inc. has received four awards totaling $4,660,331.59 through the Mississippi Rural Health Transformation Program, a state initiative funded by the Centers for Medicare & Medicaid Services. Governor Tate Reeves announced the four RHTP awards on September 14, as part of 167 awards totaling more than $104 million statewide. The awards announced will […]
Delta Health Center Receives Funding
Delta Health Center, Inc. has received four awards totaling $4,660,331.59 through the Mississippi Rural Health Transformation Program, a state initiative funded by the Centers for Medicare & Medicaid Services. Governor Tate Reeves announced the four RHTP awards on September 14, as part of 167 awards totaling more than $104 million statewide. The awards announced will […]
Lexology Index Recognizes Five Hecker Fink Partners in 2026 Business Crime Defence Guide
Hecker Fink Partners Shawn Crowley, Jenna Dabbs, Mike Ferrara, Sean Hecker, and Amy Jeffress have been recognized in the Lexology Index guide for Business Crime Defence. The 2026 guide honors leading lawyers worldwide who “stand out among peers for their exceptional work representing companies, corporate officers, and individuals in criminal litigation arising from their business activities.”
Talkiatry Earns Joint Commission Accreditation for Behavioral Health Care
/PRNewswire/ -- Talkiatry, the nation's largest psychiatric provider group and the preferred in-network psychiatry partner for more than 70 U.S. health...
AkzoNobel is selling its Southeast Asia decorative paints business to Nippon Paint for $1.35 billion
The deal covers seven countries and is expected to generate about $1 billion in net cash proceeds after taxes and minority partners
Gallery of Unearthing the Ground: Architecture and the Politics of Waste - 2
Image 2 of 15 from gallery of Unearthing the Ground: Architecture and the Politics of Waste. Fresh Kills Park. Image © USEPA Environmental-Protection-Agency - December 6, 2012 via Wikipedia under Public Domain
Gallery of Unearthing the Ground: Architecture and the Politics of Waste - 5
Image 5 of 15 from gallery of Unearthing the Ground: Architecture and the Politics of Waste. Fresh Kills Park. Image © erial View Courtesy of NYC Department of Parks and Recreation
The Co-op of Batesville
Serving the community for more than a decade Locally owned and operated businesses are a staple of the Delta economy, providing personalized service to their customers. The Co-Op of Batesville is a prime example. For 11 years, owners Steve and Kay Nickle have provided outdoor- themed supplies and apparel to citizens of Batesville, […]
Wisconsin health officials warn of lead risk in antique dishes at rummage sales
State health department urges shoppers to be careful of items that could contain lead.
Spooky season watchlist
In October 2024, I drove into Gambrill State Park after dusk and joined others carrying blankets and lawn chairs — flashlight streams lighting the road and parking lot — as
Dan Campbell refuses to talk about Kelvin Sheppard’s job security
Detroit Lions coach Dan Campbell wouldn’t discuss DC Kelvin Sheppard’s job security after another defensive meltdown.
‘An anchor’: Oakshire fans celebrate, grieve as business prepares to shut down
Oakshire Public House has been a gathering space in the Whiteaker neighborhood since 2013 and holds many individual and community memories. Oakshire as a company is closing, but it plans to transition the Public House to a new company in the next two months, keeping the location open through the process.
PFF ranks Michigan State's top five offensive players vs. Wisconsin
Check out who PFF ranked as Michigan State's top five offensive players against Wisconsin.
AI game mashup videos on social media spark debate and backlash among players and modders
The Claude-created videos overlay one game on top of another to make a rudimentary ‘mashup’…
Android Auto could soon stop working on millions of phones
Android Auto appears to be preparing another compatibility cutoff, with Android 10 users now being warned that support will end soon.
Universal Expands EMEA Retail and Partnerships for 'Shrek 5'
Universal builds excitement for 'Shrek 5's' summer 2027 release with new EMEA retail, events and partnerships. Donkey spin-off film set for 2028 release.
Jagex responds to use of generative AI in RuneScape trailer made by "trusted external partner"
Developer removes promotional material as it investigates situation, says it highlights "an issue with our own processes which we must address"
'Totally Spies!' Expands Licensing with Apparel and Jewelry Deals
Banijay Kids & Family announces new "Totally Spies!" licensing agreements spanning apparel, jewelry and publishing as the franchise marks 25 years.
The 2026 Lookout List: Health and Wellness
Are you feeling centered? This is a place where we value having aligned chakras, purposeful movement, a good gym to frequent and a good dispensary to drop into (for those that partake). For our Health and Wellness category of the Lookout List, we asked you for the best spots to drop into for yoga, mindful moments, health food and more.
Medicare-for-all is back. Now comes the hard part.
Democrats are reviving an old idea. Now they have to define it and pay for it.
After success in Ascension with steel plant, Iberville Parish proposes its own industrial zone
Proposed industrial area would abut the RiverPlex MegaPark in Ascension, which has drawn billions in investment and pollution concerns
Google admits not every Android app runs great on Intel Googlebooks
‘A small handful’ of apps apparently need some ‘developer tuning.’
$350 million Memorial Health project to bring road and parking changes
A $350 million Memorial Health project will add a 90-bed tower, cafeteria, loading dock and parking garage.
Yale School of Medicine On the Science of Childhood Anxiety, Say, Anxiety Disorders Are the Most Common Mental Health Challenges In Youth
Credit: Matt Bradbury October 5, 2026 - By Isabella Backman - Anxiety disorders are the most common mental health challenges in youth. Left untreated, they can disrupt the lives of both children and their families. The good news is that with intervention, most children will overcome these conditions. Across Yale School of Medicine, scientists are working to understand anxiety at every level, from common anxious behaviors to molecular biomarkers in the brain. They are using their findings to develop and disseminate new evidence-based treatments for childhood anxiety. Today, the go-to treatment for childhood anxiety disorders is cognitive behavioral therapy (CBT). This is a form of psychotherapy that teaches children skills for confronting anxious thoughts and helps them practice managing situations that cause anxiety. While it is the gold-standard treatment backed by considerable scientific evidence, up to 50% of children will not see sufficient benefit from CBT alone. Wendy Silverman, PhD, Alfred A. Messer Professor in the Child Study Center, co-directs the Anxiety and Mood Disorders Program alongside Eli Lebowitz, PhD, associate professor in the Child Study Center. One of their main interests is learning how to improve outcomes beyond CBT. “We’re developing cutting-edge, research-based knowledge that can reduce the suffering that anxiety causes children and their families,” says Silverman. Changing parent behavior YSM experts are investigating how to improve CBT outcomes for children by involving the parents. Silverman’s research has uncovered two main components of parent intervention that improve childhood anxiety: not enabling children to completely avoid the things that make them anxious and taking steps to enhance their autonomy. Parents may unintentionally reinforce their child’s anxiety by allowing them to avoid what makes them anxious. They also may unintentionally limit the children’s sense of autonomy by being overly intrusive. “One of the things that we take pride in is that we’ve focused on trying to understand what parents need to do, and to test our ideas and see if changing the parents’ behaviors is enhancing the effects of CBT,” Silverman says. “Our findings thus far suggest that they do." As much as CBT can be helpful, it can also be challenging to get one’s child to do the necessary steps for CBT to work. This is one important reason why Lebowitz created a novel intervention program for parents named Supportive Parenting for Anxious Childhood Emotions (SPACE). Existing intervention programs often teach parents to act as therapists for their child, such as training them on how to practice breathing exercises. “It makes sense, but this doesn’t work very well in practice,” says Lebowitz. “And part of the reason, I think, is that it’s not easy to get your kid to do things, especially if they’re not excited about doing it.” SPACE is unique because it focuses entirely on parent involvement and changing parental behavior—children are not involved in the sessions. For example, parents learn how to use supportive messages that convey confidence that their child can tolerate and manage distress. “It might sound like a parent saying to a child, ‘I get that this is really hard for you, but I know that you can handle it,’” Lebowitz says. The program also works with parents to identify the ways in which they are accommodating anxious behaviors. “We’ll pick one thing that parents are doing that is an accommodation and help them make a detailed plan for how they’re going to change that,” Lebowitz explains. Treating Anxiety in Children and Adolescents Much of the existing research on SPACE has focused on parents of children under age 14. Ongoing studies are now exploring its use with parents of older teens. “Both anxiety and accommodation can interfere with normative developmental shifts during the teen years, including increased autonomy and individuation from parents,” says Rebecca Etkin, PhD, associate research scientist in the Child Study Center. “In this sense, SPACE may be particularly well-suited for anxious teens and their parents. We want to see whether it is effective during this distinct developmental window.” Unfortunately, many families in need of CBT face barriers, including limited availability of services and geographic constraints. One way to improve access is digital interventions. Silverman and her team are developing an evidence-based digitized intervention program for parents that they can access directly from their computer or smart phone. “The work we’re doing will be one of the very few parent interventions that is digitized and importantly tested for effectiveness,” she says. Creating interventions for anxiety-related challenges Silverman and Lebowitz recently received a generous gift to develop and test other interventions that help parents reduce other child anxiety-related behavioral and emotional difficulties, such as restrictive eating and unexplained somatic symptoms. One of these projects in particular focuses on understanding the risks of social media and its potential benefits, including offering a sense of connection. “A lot of research has focused on the idea that social media is harmful and the less of it the better,” says Lebowitz. “But we actually see is that this is not quite right—there are negatives, but there are also positives. So, we’re trying to get a little bit more nuanced of a picture.” The team is working with teens with social anxiety and their parents over an extended period to better understand their social media habits and how their anxiety levels affect engagement with different platforms. The teens will answer questions sent to an app on their phones about mood and social media usage in an effort to capture emotional responses as they unfold. “We hope to develop interventions that can help make the best of social media while protecting against the more problematic effects,” Lebowitz says. The brain’s role in anxiety Researchers are also testing therapies to address anxiety at the neurological and molecular levels. In collaboration with Dylan Gee, PhD, professor of psychology in Yale's Faculty of Arts and Sciences, and Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience at Yale School of Medicine, Lebowitz and Silverman are using brain imaging to identify changes in a child’s brain before and after parents enroll in SPACE. In one study, children viewed anxiety-inducing images while undergoing magnetic resonance imaging (MRI); the researchers conducted scans with and without the children’s parents nearby. Before SPACE, children’s brains were better able to activate the regulatory circuitry needed to turn off an anxious response when their parents were nearby. But after SPACE, children could activate this circuitry even without the parent around. “As parents work on gradually reducing some of their accommodations, you can see a child get better at regulating their own fear system in the brain,” Lebowitz says. “It’s remarkable.” Research into the molecular underpinnings of anxiety can also inform new childhood anxiety treatments. In a recent study, Lebowitz, Silverman, and Flora Vaccarino, MD, Harris Professor in the Child Study Center, discovered that a protein known as fibroblast growth factor 2 (FGF2) could be protective from the toxic effects of stress. FGF2 levels in children and their parents were linked to the children’s risk of developing anxiety and depression, the study showed. The findings could help explain why some children who are exposed to early life trauma such as poverty or abuse are more prone to developing mental health disorders. And FGF2 could be a target for treatment. “This is very novel because it starts to give a clue to what is the molecular chain that connects those lived experiences to the actual psychological outcomes,” Lebowitz says. New ways to study and treat childhood anxiety Michael Crowley, PhD, associate professor in the Child Study Center, collaborates with Silverman and Lebowitz to study the role that attention plays in development and maintenance of childhood anxiety. There is a large body of research that shows that anxious children, like anxious adults, are prone to focus on threatening stimuli such as angry faces compared with neutral faces. This has led to innovative interventions that involve attention retraining. The idea is that if experts train children to look away from threatening stimuli, it may reduce their anxiety—especially children with social anxiety who are most prone to attend to threats. The researchers have just completed a clinical trial for attention retraining with 10- to 14-year-olds with social anxiety disorders and are currently analyzing the findings. Besides this innovative attention retraining research, as Crowly notes, “I like to design tasks that are engaging to kids,” Crowley says. “My goal is to assess something without the kids knowing what we are assessing.” With this goal in mind, Crowley has created a virtual game, named Boom, to study threat processing in children with anxiety disorders. The game is similar to that of hot potato—the child and three digital players take turns virtually passing a ball to each other’s gloves. At some point, the ball turns into a bomb, and as the bomb lands in each player’s glove, the outline of the glove turns yellow. The goal is to avoid having the bomb go off in your glove. What isn’t obvious is that the game is designed to measure different types of threatening stimuli, both ambiguous and direct. In the game, the direct threat occurs as the bomb is traveling towards your glove. The ambiguous threat is the yellow outlined glove as it is unknown where the bomb will travel next. While children play the game, Crowley’s team measures their brain activity using electroencephalography (EEG). The researchers have discovered that in kids with anxiety, the brain reacts more strongly to ambiguous threats than it does in their peers, but less strongly to direct threats. They believe that the initial abnormally large brain response to not knowing where the bomb is going impairs the brain's ability to properly respond when the threat is actually traveling the child’s way. “The brains of children with anxiety are unable to differentiate between threats you need to do something about and those that are not your problem.” Michael Crowley, PhD, develops innovative games for studying anxiety in children and adolescents.Credit: Matt Bradbury Based on these insights, Crowley hopes to study whether interventions like attention training could restore appropriate threat processing. Crowley’s team is also working on a test called the Balloon Risk Avoidance Task, which evaluates risk-taking and avoidance behaviors. It features a digital balloon that is full of air and about to burst. Kids have six seconds to let air out of the balloon. The more air they let out, the less risk they face that the balloon will pop. But at the same time, the balloon becomes less valuable as it deflates. “The more air you keep in the balloon, the more points you get,” Crowley explains. So far, the researchers have found that when the balloons pop unexpectedly, teens with social anxiety show distinct brain responses. Studying these responses can help psychologists understand the underlying pathways driving the various manifestations of anxiety. The genetics of anxiety When Thomas Fernandez, MD, associate professor in the Child Study Center and of psychiatry, was still in training, there was a lot of excitement about understanding the genetics associated with autism spectrum disorder. Since then, scientists have identified around 250 genes associated with autism. The genetic contribution to anxiety disorders, on the other hand, has historically received less attention. Anxiety is less heritable than autism, but the genetic contribution for anxiety disorders that emerge in childhood may be higher than for anxiety disorders overall. While scientists estimate the heritability of anxiety disorders in general to be around 30% to 50%, some studies suggest higher heritability for certain childhood-onset anxiety presentations. “I saw firsthand how researchers in the field went about finding vulnerability genes for autism,” Fernandez says. “So, we’re using a very similar playbook for childhood anxiety.” “I saw firsthand how researchers in the field went about finding vulnerability genes for autism. So, we’re using a very similar playbook for childhood anxiety.” Thomas Fernandez, MD Associate Professor In the Child Study Center and in Psychiatry Now, Fernandez and Emily Olfson, MD, PhD, assistant professor in the Child Study Center, are studying children and their parents to identify genetic changes that are present in the child but not the parents, known as “de novo mutations.” “All of us have some de novo mutations—maybe about 50 to 100 sprinkled throughout the genome,” Olfson says. “But when they occur within the coding regions of genes, they can be really disruptive.” Previous research shows that people with autism have higher rates of damaging de novo mutations than the general population. In 2022, Olfson, Lebowitz, Silverman, and Fernandez published a study on 68 children and their families that found that children with anxiety had similarly high levels of these mutations. Studying de novo mutations can help point the researchers to where they should be looking for genes associated with anxiety. “The end game is using the genes to steer us toward the right part of biology that we can then target to come up with better treatments,” Fernandez says. Building on those findings, the team is now studying more families to better understand how these de novo mutations, along with other genetic and environmental factors, shape pediatric anxiety disorders. They recently received a National Institutes of Health grant to enroll 750 new families over the next five years. Olfson is the principal investigator, with co-investigators Lebowitz, Fernandez, Silverman, and Shuangge Steven Ma, PhD, department chair and professor of biostatistics at Yale School of Public Health. Neurodevelopment, Risk Genes, and Mental Health Conditions - The Olfson Lab Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, is interested in how different anxiety disorders differ genomically. “We are studying social phobia, panic disorder, and generalized anxiety disorder, working to understand why people differ in their risk to these specific anxiety disorders and evaluating various risk factors,” he says. Gelernter was recently involved in one of the largest studies to date of the genomics underlying anxiety disorder. The study included around 122,000 people with anxiety disorders and around 730,000 without. It found that some genetic differences associated with anxiety were linked to signaling that helps reduce overactivity in the nervous system. Many anxiety medications available today work by targeting this process. “It’s nice when the biology that you get out of a large genome-wide study ratifies things that we already know because that can help increase confidence in further findings from the study,” Gelernter says. Uncovering the neurobiology of psychiatric disorders John Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and chair of the Department of Psychiatry, is interested in the neurobiology of psychiatric disorders, including post-traumatic stress disorder (PTSD), of which anxiety is a major symptom. In the late 1980s, Krystal’s team discovered that the drug yohimbine activated symptoms in patients with PTSD. “This was the first time we could link a specific biological mechanism to the symptoms of PTSD,” Krystal says. At the time, he adds, this finding was highly controversial. “A lot of people felt that PTSD was a purely psychological syndrome that didn’t have an underlying biology.” Since then, Krystal has dived deep into understanding the neurobiology of PTSD to learn how to better treat it. His team is evaluating the use of ketamine and psychedelics. These would be among the first treatments to be developed specifically for PTSD. They may also be applicable for other disorders including anxiety disorders, Krystal adds. An important gap in PTSD treatment is the absence of biological tests that inform how to best help patients manage their PTSD symptoms. A doctor doesn’t diagnose cancer based on how they feel. Rather, they use tests of the biology of the cancer to determine the best course of treatment. “And we can’t do that in any psychiatric disorder other than Alzheimer’s disease,” Krystal says. “But now we are building a foundation for this approach to the treatment of anxiety disorders for the first time.” Source: Yale School of Medicine
Dan Campbell: I'm not talking about firing Kelvin Sheppard
The Lions defense was unimpressive in the first three weeks of the 2026 season and things didn't get any better in Sunday night's loss to the Panthers.
Mr Bean Brand Expands with New Global Licensing Partnerships
Banijay Kids & Family announces expanded Mr Bean licensing deals including Royal Stacks burgers, apparel, watches, toys, and arcade games worldwide.
Independent candidates hope to shake up status quo, give Oklahoma voters alternative option
Frustration with mainstream political parties prompted a number of independents to file for office.
Three sheriff’s offices sign up for jail mental health hold reimbursements under new Wyoming law
The law allows the health department to pay jails for holding and treating people with mental illnesses while they await a bed at the state hospital.
Democratic socialists scored big primary wins. But that’s not the whole story.
DSA-backed candidates, sharp critics of Israel, made historic gains. But a closer look makes clear they’re not taking over the Democratic Party – so far.
Girls flag football is a fast-growing high school sport
Participation has surged more than 550% nationally in the past four years.
White nationalism’s appeal runs deeper than partisan politics
How extensive is white nationalism’s appeal among the broader public, and who is drawn to this extremist ideology?
Ruth Tucker joins the Bulletin
The Bulletin is excited to welcome Ruth Tucker as the nonprofit's Advancement Services Coordinator. As Advancement Services Coordinator, Tucker will support the daily operations of the Advancement team, including gift entry, event registration entry, acknowledgements, and administrative support in the implementation of the department's fundraising tasks.
When midterm politics get in the way of governing
After some proposals fell apart in the Senate, both parties will need to figure out to message the failed votes while convincing voters they should be running the show.
TV Tinsel: 'NCIS' franchise explores new territory in Big Apple
The long arm of naval law is stretching into the Big Apple as the new “NCIS: New York” premieres on CBS Tuesday and streams on Paramount+ Wednesday. The omnipresent “NCIS”
An El Niño–fueled ocean wave could raise California flood risks as Florida’s vaccine debate sparks outbreak concerns
An El Niño–driven ocean surge threatens coastal flooding, researchers warn that a plan to loosen vaccine requirements will increase measles risks in Florida, and experts debunk a viral TikTok cold remedy
Nursing alumna helps shape care at Children’s Healthcare of Atlanta
Rebekah (Goforth) Carter, NUR ’14, grew up receiving care from Children’s Healthcare of Atlanta. As a nurse now, she’s part of the team that provides vital pediatric services.
The Democratic Party is fighting itself, even in Cleveland
A local look at the national divide between progressives and moderates in the Democratic Party.
Lawrence Tech launches program to ease automakers’ reliance on rare earth materials
Lawrence Tech's Centrepolis Accelerator and USCAR are partnering to find critical material innovations to make the U.S. auto industry more competitive.
Backlash to Trump hasn’t bolstered Florida Democrats’ voter registrations
More than twice as many Democrats switched their party to Republican since September 2024 than the other way around.
DCCC names Pearson to ‘Red to Blue’ class in effort to hold TN-9: Exclusive
The DCCC added Justin Pearson to its Red to Blue program, hoping to defeat Republican Brent Taylor and keep control of TN-9.
New kiosk is Erie County's latest effort to reduce drug overdoses, STDs
The kiosk was installed outside the Erie County Department of Health, 606 W. Second St., in mid-September and officially unveiled Oct. 1.
Inter Join Barcelona, EPL Giants for Stuttgart Talent
Inter got only slightly younger defensively in the summer and have earmarked Finn Jeltsch to bring in fresh legs at the position in the future. The Nerazzurri parted ways with Stefano Acerbi, Stefan D...
Democrats Expect Record Number of Women in Party in House After Midterm Elections
Democrats are increasingly confident they will have a record number of women serving in the House next year, after backing women in competitive districts they are now positioned to win.
‘I’m here to save lives’: Inside the unlikely Biden-Trump partnership to secure a Gaza ceasefire
Secure rooms in the US Capitol are cavernous compared to the White House Situation Room. They are designed for full committees or larger gatherings, not intimate discussions. On Nov. 20, 2024, Jake Sullivan and I had gone to one of those rooms to brief our successors two weeks after Donald Trump resoundingly defeated Kamala Harris.
Digital Science appoints Charlesworth as strategic sales partner in China
Agreement builds on Charlesworth’s existing work with the Chinese scholarly publishing community and knowledge of market