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Every NFL franchise's biggest position to improve, plus free agency and draft solutions
The Cowboys need to add to their defense, and they have the draft capital to make it happen.
By Director Mr. Sakurai, Kirby Air Riders: Development Insights — Part 5 - News
Join Kirby Air Riders director Masahiro Sakurai as he shares insights into the development and details behind some of the game's modes and features. Check out the rest of the interview Part 1: Air Ride and Top Ride Part 2: Cramming everything into S…
A surprising foam discovery could change everyday products
Foams have long baffled scientists because liquid drains from them far sooner than theory predicts. New research shows the reason: the bubbles don’t stay put—they rearrange, opening pathways for liquid to escape. The key factor is the pressure needed to shift bubbles, not just push liquid through them. This insight reshapes how we understand foams and could improve everyday products.
Every bulb on Govee’s new outdoor string lights can display multicolor effects
Level up your patio.
Starmer says ‘every lever’ will be explored to ease rising costs of living from Iran conflict
PM will chair Cobra meeting with key ministers and Bank of England on Monday, as experts warn of economic shock
Today's NYT Connections: Sports Edition Hints, Answers for March 23 #546
Here's today's Connections: Sports Edition answer and hints for groups. These clues will help you solve The New York Times' popular puzzle game, Connections: Sports Edition, every day.
Everything you need to know about 'BTS: The Return,' the new Netflix documentary
On Friday, Netflix will release a documentary about the biggest band in K-pop, BTS. It is titled “BTS: The Return.” It is from director Bao Nguyen. He is known for his work on “The Stringer”...
Everything you need to know about 'BTS: The Return,' the new Netflix documentary
On Friday, Netflix will release a documentary about the biggest band in K-pop, BTS. It is titled “BTS: The Return.” It is from director Bao Nguyen. He is known for his work on “The Stringer”...
Everything you need to know about 'BTS: The Return,' the new Netflix documentary
On Friday, Netflix will release a documentary about the biggest band in K-pop, BTS.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Bucket hats and home run chains: Getting decked out for baseball season at Poor Boys Sports
From shirts featuring new players to hats in every color, Poor Boys Sports has all your Orioles merch needs for Opening Day.
30 Must-Have Gadgets For Every Room In Your House
Prepare to power up your homes, my friends!
Everything you need to know about the ‘Hannah Montana 20th Anniversary Special’ — How to watch, premiere time, who’s coming back and more
Sweet niblets! Hannah Montana is back for an anniversary special. Here's what to know.
Assemblywoman Alexandra Macedo says César Chávez allegations are "just the tip of the iceberg"
California lawmakers this upcoming week are set to move quickly to rename César Chávez Day to Farmworkers Day ahead of the holiday that takes place every year on March 31.
The best seafood restaurant in every state, according to Yelp
Yelp picked the best seafood restaurant in every state based on customer reviews.
'Everybody Loses' author discusses the meteoric rise of sports gambling
Two years ago, Americans bet $120 billion on sports, a 27% increase from the previous year. That figure grew to $150 billion in 2024. Journalist Danny Funt investigates what's considered one of the most consequential — and least scrutinized — shifts in modern American sports in his new book, "Everybody Loses: The Tumultuous Rise of American Sports Gambling."
Gen Z really, really loves China's trains
This is a condensed version of Business Insider Today, a newsletter that gives you a look at the week’s top stories. Sign up here to get the full Business Insider Today in your inbox every day for the top stories in markets, tech, and business.
AI was everywhere at gaming’s big developer conference
Developers say it removes the craft from making games.
How investors use the BRRRR strategy to scale real estate portfolios
"My strategy is basically to use every property to fund the next one," said one real estate investor.
Prior authorization can delay needed health care. A new 'Gold Card' targets that bottleneck.
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Bloodstained: The Scarlet Engagement listed for Nintendo Switch, plus an unannounced 505 Games Switch 2 title
Bloodstained: The Scarlet Engagement has been listed for Nintendo Switch alongside an unannounced Switch 2 title from 505 Games. The Scarlet Engagement, a sequel to the original, was previously announced last year. Although there wasn’t any news about a Nintendo release, the latest discovery suggests that we’ll be getting it on Switch at the very least. It’d be somewhat surprising...
Today's NYT Connections: Sports Edition Hints, Answers for March 22 #545
Here's today's Connections: Sports Edition answer and hints for groups. These clues will help you solve The New York Times' popular puzzle game, Connections: Sports Edition, every day.
Urban Entertainment Society crowns this year’s Beat Battle champion
The Urban Entertainment Society hosted its annual Beat Battle at the Chris Young Cafe on Friday, highlighting talented students across every major.
"Derby of the dead child": This match changed football forever
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Who is Jazzy Davidson? True freshman guard leads USC into March Madness
Jazzy Davidson leads the USC women's basketball team in every major statistical category. Now, she leads the Trojans into March Madness.
Franklin Templeton CEO Jenny Johnson on the values needed to keep a billion-dollar business in the family
Jenny Johnson is CEO of $12 billion family-run asset management business Franklin Templeton, which oversees nearly $2 trillion in assets. Growing the company and succeeding in the role took everyone in the family, including herself, putting their egos aside.
My twins separated for the first time at 19
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iPhone spyware is everyone's problem now
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Microsoft Promises Slew of Windows 11 Changes in Response to "Microslop" Criticisms
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Democrats excluded from USC governor debate urge rivals to boycott
Four Democrats running for California governor who were excluded from an upcoming debate at USC urged their rivals to boycott the event because it excludes every candidate of color.
Why the Trump administration is easing sanctions on certain Iranian oil stockpiles
Trump administration officials are making a desperate push to secure every available barrel of oil amid a worsening energy crisis — even if it means lifting sanctions on the very country that they’re fighting against.
Today's NYT Connections: Sports Edition Hints, Answers for March 21 #544
Here's today's Connections: Sports Edition answer and hints for groups. These clues will help you solve The New York Times' popular puzzle game, Connections: Sports Edition, every day.
Swalwell sees attacks from left and right as California's race for governor heats up
There is finally a breakaway leader in California’s crowded race for governor, at least by one measure: Eric Swalwell is just about everyone’s favorite target.
2026 NCAA Men's Basketball Tournament Highlights: Round of 64
The 2026 NCAA Men’s Basketball Tournament continues on Friday, and we’re tracking every top moment of the Big Dance!
Nintendo reportedly planning Switch 2 revision with replaceable battery for Europe
New report details Nintendo Switch 2 revision which will feature a replaceable battery for Europe.
Google Unveils New Process For Installing Unverified Android Apps
It’s no secret that Google really doesn’t like it that people are installing Android applications from any other source than the Play Store. Last year they proposed locking everyone int…
A Grip on Sports: The Zags survive a first-round rock fight in Portland, one that also caused contusions for those watching from home
A GRIP ON SPORTS • There was one thing I was certain of when I began writing this column almost 15 years ago. The day Chuck Norris died, I would share my story of the lone interaction I had with the “Walker, Texas Ranger” star. It has everything. High school football. A rickety press box. Family. Sports writing. But, alas, it may have to wait. Today is just not the day.
How did these flowers evolve to survive a megadrought?
A multi-year megadrought in the Western U.S. has claimed untold populations of wild plants. Amid the conditions, some have survived. Scientists have produced a stunningly complete picture about how populations of one particular flower – the scarlet monkeyflower – made it through. In a new study published in the journal Science, a team of scientists spent decades studying and sampling select populations of scarlet monkeyflowers in California and Oregon. Through genetic sequencing, the team discovered that the populations that did best went through genetic changes in a short time period. This is known as rapid evolution. The team found that three of the populations that recovered the BEST adapted their stomata to open less, so they could conserve more water. Stomata act like a plant’s pores, managing gas exchange and water loss. This allowed the scarlet monkeyflowers to hunker down in the drought and survive. Interested in more stories about rapid evolution? Email us your question at shortwave@npr.org.Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.Listen to Short Wave on Spotify and Apple Podcasts.This episode was produced by Jeffrey Pierre, Rachel Carlson and Hannah Chinn. It was edited by Christopher Intagliata and Rebecca Ramirez. Aru Nair checked the facts. The audio engineers were Becky Brown and Robert Rodriguez.
The nation’s cartoonists on the week in politics
Every week political cartoonists throughout the country and across the political spectrum apply their ink-stained skills to capture the foibles, memes, hypocrisies and other head-slapping events in the world of politics. The fruits of these labors are hundreds of cartoons that entertain and enrage readers of all political stripes. Here's an offering of the best of this week's crop, picked fresh off the Toonosphere. Edited by Matt Wuerker.
Trump’s global agenda flies into domestic headwinds
Even as US President Donald Trump calls for international support for the war in Iran, within the US there are dissenting voices, as not everyone is convinced that war is the answer. What is clear is that domestic factors will increasingly limit Trump’s foreign policy and diplomatic engagement. Academic Derek Grossman discusses the issue.
Dothan senior breaks 75-year barrier with international science fair qualification
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Valve’s huge SteamOS 3.8 update adds long-awaited features — and supports Steam Machine
Xbox Ally gets SteamOS improvements too.
Louisville tops South Florida: Highlights and Postgame Videos
Feel free to watch every second of these, or turn the highlight videos off around the 9-minute mark of the second half. Either way, go ahead and soak this up. It’s been a while. Highlights: Pat Kelsey postgame from the bus: Locker room celebration:
Brooklyn businesses, consumers feeling the pinch from soaring oil prices
The soaring crude oil prices continue to push up the price at the pump, but it's also impacting everything from airfare to farmers, and products you buy at the store.
2026 NCAA Men's Basketball Tournament Highlights: Duke Escapes Siena
The 2026 NCAA Men’s Basketball Tournament tips off today, and we’re tracking every top moment of the Big Dance!
Today's NYT Connections: Sports Edition Hints, Answers for March 20 #543
Here's today's Connections: Sports Edition answer and hints for groups. These clues will help you solve The New York Times' popular puzzle game, Connections: Sports Edition, every day.
Bungie Reveals All Details of Marathon's First Raid, Cryo Archive; Goes Live on March 20 and Weekends Only
Here's everything you need to know about Marathon's Cryo Archive raid that goes live on March 20, which will only be available on weekends.
Steam Spring Sale 2026: The Best And Biggest PC Gaming Deals
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Green Bay Packers officially announce full 2026 coaching staff
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Essentia Health holding advance care planning classes
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I tried custom soda chain Swig for first time; left disappointed
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Spring Position Battles: Cornerback
If there’s one constant across the Mizzou defense entering the 2026 season, it’s transition — and nowhere is that more apparent than at cornerback. Like nearly every other defensive position group, the Tigers lost a massive amount of production at corner this offseason. Both starters from last fall, Dreydon Norwood and Toriano Pride, Jr., have […]
Trading or gambling? How a new way to wager on sports is evading Nebraska’s betting ban
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2026 NFL mock draft: Every team makes a pick -- even those without a first-rounder
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Everything New In Fortnite Chapter 7 Season 2
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Michael Kay: 'I don't like wrapping sports in a flag and preaching patriotism'
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A more personal digital health experience for people in Europe
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Crisis or opportunity? Thousands of baby boomer business owners to retire in West Michigan
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Today's NYT Connections: Sports Edition Hints, Answers for March 19 #542
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Chia Seed Water Is Going Viral for Gut Health. Dietitian Shares 1 Warning Before Trying It
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5 Portland sports bars where you can watch every wild March Madness moment this year
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Snowflake Launches Project SnowWork, Bringing Outcome-Driven AI to Every Business User
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What everyone gets wrong about the science of lip-reading
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Samsung Is Now Allowing Users In A Key Market To Use The Galaxy S26 Series For A Year By Paying Just 50 Percent Of The Price
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Hundreds of Connecticut companies meet with lawmakers at annual Business Day event
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China targets measurement science in tech race with U.S. - Futura-Sciences
The invisible backbone of modern technology Behind every electronic chip, satellite, and medical device sits a system of measurement. Without extreme precision in units, standards, and calibration methods, no technology operates reliably. Metrology ensures that a nanometer is actually a nanometer, that a processor performs exactly as intended at atomic...
We picked every game of an NFL March Madness bracket -- and a 6-seed made the Final Four
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Video: Business Report Hall of Fame honoree Benny Alford
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By Director Mr. Sakurai, Kirby Air Riders: Development Insights — Part 4 - News
Join Kirby Air Riders director Masahiro Sakurai as he shares insights into the development and details behind some of the game's modes and features. Check out the rest of the interview Part 1: Air Ride and Top Ride Part 2: Cramming everything into S…
Protalix BioTherapeutics Reports Fiscal Year 2025 Financial and Business Results
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Protalix BioTherapeutics Reports Fiscal Year 2025 Financial and Business Results
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Beat our March Madness expert bracket: Picks for every NCAA game
Detroit Free Press sports columnist Shawn Windsor picks every game in 2026 March Madness. Check out his predictions and see if you can beat him.
A dietitian and doctor review RFK Jr's new food pyramid
The new food pyramid was released earlier this year. It emphasizes protein, full-fat dairy and what Health and Human Services Secretary Robert F. Kennedy Jr. calls “healthy fats.” These guidelines influence the standards for school lunches, food labeling and programs like SNAP. Today on the show, Short Wave co-host Emily Kwong chats with registered dietitian nutritionist Shana Spence, and Dr. Sarah Kim, a diabetes specialist, about the new guidelines. Plus, NPR’s Reflect America fellow Kadin Mills unpacks how the new food pyramid could change school lunch trays. Check out more of Kadin’s coverage about the changes in dietary guidelines.Interested in more health science? Email us your question at shortwave@npr.org.Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.
Why Denver should care about conservation easements — even if you’ve never set foot on a ranch
By Jason Swan I live in Denver. I drink tap water from my kitchen sink, hike close to home when I can, worry about wildfire smoke every summer, and try, like many families, to keep up with the rising cost of living. I don’t own land. I don’t ranch. I don’t farm. And yet one […]
Anti-Fraud Practices Your Bank Should Teach Every Small Business Customer
Payments fraud against businesses is skyrocketing, but banks and customers can combat it together.
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The race for a safe Democratic House seat offers clues about the party’s future
It’s Primary Day in Illinois, where 15 Democrats, spanning three generations, are vying to succeed longtime Congresswoman Jan Schakowsky in the state's 9th Congressional District. We discuss what the race tells us about the future of the Democratic Party.This episode: senior White House correspondent Tamara Keith, political reporter Elena Moore, and senior political editor and correspondent Domenico Montanaro.This podcast was produced by Casey Morell and Bria Suggs, and edited by Rachel Baye. Our executive producer is Muthoni Muturi.Listen to every episode of the NPR Politics Podcast sponsor-free, unlock access to bonus episodes with more from the NPR Politics team, and support public media when you sign up for The NPR Politics Podcast+ at plus.npr.org/politics.
Today's NYT Connections: Sports Edition Hints, Answers for March 18 #541
Here's today's Connections: Sports Edition answer and hints for groups. These clues will help you solve The New York Times' popular puzzle game, Connections: Sports Edition, every day.
Apple Studio Display XDR Hands-On: Better Than the Pro Display XDR in Almost Every Way
Apple replaced the $4,999+ Pro Display XDR with the better, more affordable Studio Display XDR, so we thought we'd pick one up to test out and compare to the now-discontinued Pro Display XDR. Subscribe to the MacRumors YouTube channel for more videos. The Studio Display XDR is the same size as the Studio Display at 27 inches, and it has the same 5K resolution.
Trombone emoji designed by Maryland students headed to iPhones everywhere
The trombone emoji designed by a group of Maryland students is headed to iPhones everywhere.
Now everyone in the US is getting Google’s personalized Gemini AI
Suggestions based on what’s in your Gmail inbox or YouTube viewing history.
The 2026 Lollapalooza lineup just dropped: Everything to know about dates, headliners, tickets and more
The annual four-day music festival officially returns to Grant Park in Chicago, Illinois July 30-Aug. 2 with over 150 musicians including this year's headliners Charli XCX, Tate McRae, Lorde, Olivia Dean, John Summit, Jennie, The Smashing Pumpkins and The xx.
A Massive Midterm Wave Isn’t Forming Yet. Here’s Why.
This is an era not just of hyperpartisanship, but of negative partisanship, in which partisans often hate the other side even more than they love their own. Many voters thus tend to see everything on a binary basis. Any given election outcome is seen as either a landslide victory or an unmitigated disaster. There is little appreciation, or even tolerance, for gradations between those outcomes.
AGU and Content With Purpose announce new digital series exploring science in action
“Our World, Our Future” will connect scientific discovery with lived experience and demonstrate how research directly affects people and communities everywhere.
We Saw Starfield's Big Overhaul and DLC - Is It Enough to Revive Bethesda's Space RPG?
Starfield is getting new DLC, Terran Armada, along with some major quality-of-life updates. And a PS5 version! We got an extended first look at everything on its way to Bethesda's big outer-space RPG.
Introducing the Ultimate Earbuds for Every Workout: Nike x Powerbeats Pro 2
The special-edition earbuds deliver premium sound that empowers athletes to tune out the noise, stay focused on their goals and push beyond their limits.
Garmin Launches WhatsApp Integration for Watches
Everything you need to know about Garmin's new WhatsApp integration on their newer watches.
Everything Coming in Starfield’s Free Lanes Update & Terran Armada DLC
April 7 marks the beginning of a new era for Starfield, with the game’s biggest free update yet, the all-new Terran Armada story DLC, and the official PlayStation 5 launch all arriving at once.
Dell XPS 16 (2026) review: Return of the king
The XPS 16 has nearly everything you want from a premium 16-inch productivity laptop and it's a worthy flagbearer for one of the most iconic notebook lines of all time.
Scientists used 7,000 GPUs to simulate a tiny quantum chip in extreme detail
Researchers have pushed quantum chip design into a new era by simulating every physical detail before fabrication. Using a supercomputer with nearly 7,000 GPUs, they modeled how signals travel and interact inside an ultra-tiny chip. Unlike earlier “black box” approaches, this method captures real materials, layouts, and qubit behavior. The result is a powerful new way to spot problems early and build better quantum hardware faster.
Donations to science often avoid scrutiny. Jeffrey Epstein used this to his advantage
Billions of dollars are invested in science every year through philanthropy, with little legal or public scrutiny. Jeffrey Epstein utilized this to cultivate scientists and launder his reputation.
Is LYON's Inspired the Best Jungler at First Stand?
The numbers say LYON's Inspired leads every jungler in the world this split. So why isn't he part of the conversation heading into First Stand?
GameStop Declares Xbox360, PS3 Retro Consoles, Millennials Are In Shambles
GameStop released a memo designating the Xbox 360, PlayStation 3, and Wii U retro consoles, reminding every Millennial who grew up with those systems they are now washed.
Nintendo Switch 2 and Switch update 22.0.0 out now, patch notes
Nintendo Switch 2 and Switch just got a new firmware update with version 22.0.0 and here are the patch notes including Friend List notes.
At 76, I still cycle, train every day, and can do 5 muscle-ups
Ngai Hin Kwok, 76, says he doesn't see a reason to slow down just because he's older.
Who has made Troy's Premier League team of the week?
After every round of Premier League matches this season, Troy Deeney gives us his team of the week. Do you agree with his choices?
GameStop declares Nintendo Wii U as a retro console, trade-in bonus offer announced
GameStop issues statement that Nintendo Wii U, PS3, and Xbox 360 are retro consoles and announces a special trade-in bonus offer.
Today's NYT Connections: Sports Edition Hints, Answers for March 17 #540
Here's today's Connections: Sports Edition answer and hints for groups. These clues will help you solve The New York Times' popular puzzle game, Connections: Sports Edition, every day.
Judge blocks RFK Jr. from scaling back childhood vaccine recommendations
A federal judge on Monday temporarily blocked federal health officials from cutting the number of vaccines recommended for every child, and said U.S. Health Secretary Robert F. Kennedy Jr. likely violated federal procedures in revamping a key vaccine advisory committee.