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President Trump Signs Executive Order Advancing Regenerative Agriculture as Part of Make America Healthy Again Agenda
President Trump Signs Executive Order Advancing Regenerative Agriculture as Part of Make America Healthy Again Agenda
Vance, an admirer of Richard Nixon, says Watergate would be 'a 12-hour news story' today
Vice President JD Vance says the Watergate scandal that brought down President Richard Nixon would have been a blip in today’s news cycle
Ecuador vs Germany Extended Highlights
Check out the full game highlights between Ecuador and Germany in the 2026 FIFA World Cup™. Announced by Ian Darke and Landon Donovan.
Ecuador vs Germany Highlights
Check out the full game highlights between Ecuador and Germany in the 2026 FIFA World Cup™. Announced by Ian Darke and Landon Donovan.
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
SBA’s Proposed Update to the 8(a) Business Development Program: A New Approach to Social Disadvantage
On June 11, 2026, the Small Business Administration (“SBA”) published a proposed rule that would fundamentally alter how individuals qualify as “socially
Rubio’s spin on the Iran MOU sounds different from Trump and Vance
For more than a week, America’s top diplomat was conspicuously quiet about something that would have seemed very much in his wheelhouse: a nascent agreement with Iran. But now Secretary of State Marco Rubio is speaking.
Microsoft Discovery Aims To Advance The Era Of Agentic Science
The cloud-based agentic AI platform aims to help human researchers overcome resource constraints and complex data challenges to accelerate science at scale.
Misericordia University Students Earn Top Honors at Pennsylvania Academy of Science's 101st Annual Meeting
Misericordia University students earned multiple prestigious awards while showcasing undergraduate research at the 101st Annual Meeting of the Pennsylvania Academy of Science (PAS), held this year on the Misericordia University campus—the first time the statewide scientific organization has hosted its annual conference at the university.
Graham Platner backs legal maneuver using Maine law to rein in political spending
Democratic U.S. Senate nominee Graham Platner wants to overturn the landmark U.S. Supreme Court ruling that enabled corporations and other outside groups to spend unlimited money on elections by any means possible. He supports a constitutional amendment and ethics rules on the high court, which the Sullivan oyster farmer included in his latest policy rollout […]
Usha Vance mocks NYT article over 'political significance' of pregnancy outfits
Second lady Usha Vance mocks a New York Times article scrutinizing the 'political significance' of her maternity outfits.
Tech: House Science advances AI bills
The House Science Committee advanced a bipartisan bill that would codify increasingly prominent artificial intelligence oversight work being done by the Commerce Department.
Yes/Boston Announces Inaugural Cohort of 12 Innovators Advancing Food and Health Solutions
/PRNewswire/ -- Yes/Boston, an initiative intended to accelerate innovation at the intersection of food systems and health, today announced its inaugural...
Poppi founder speaks about building a billion-dollar soda business
Allison Ellsworth, the founder of the viral soda brand Poppi, sits down with NBC News' Savannah Sellers to discuss how she turned a personal health issue into a billion-dollar cultural phenomenon.
Major part of student-loan repayment overhaul is blocked in court
A federal court ruled that the Education Department's proposed borrowing caps for advanced healthcare programs cannot take effect on July 1.
From The Sports Desk: Is the Tartan party over?
Scotland’s hopes of advancing to the knockouts hang by a kilting thread.
Another look at carrots and eyesight; how to get more fiber; why mosquitoes bite some people and not others; plus other stories with Vanderbilt Health sources
AARP reporter Stacey Colino interviewed Milam Brantley, MD, Associate Professor of Ophthalmology and Visual Sciences, in 2020 for a story about whether eating carrots can improve vision. Sacramento Bee reporter Samantha Agate has now used Brantley’s comments in an AI-curated story created by content specialists on the same topic that has been picked up by MSN and others. Prevention magazine interviewed Heidi Silver, RD, PhD, Founding Director of the Vanderbilt Diet, Body Composition, and Human Metabolism Core, for a story about the importance of fiber and how people can get more of it in their diet. William Schaffner, MD, Professor of Preventive Medicine, was quoted by several news outlets about public health issues, including: Women’s Health (tick bites and alpha-gal syndrome); The Washington Post (tetanus); and Healthline (why mosquitoes prefer to bite some people and leave others alone). A visit to Monroe Carell Jr. Children’s Hospital at Vanderbilt by some Banana Ball baseball players was covered by The Tennessean and WZTV Fox 17 News, and The Tennessean’s story was also picked up by Yahoo! Sports. Clarksville Now published a story written by the Montgomery County Economic Development Team, whointerviewed Bradley Stancombe, MD, professor of Clinical Pediatrics, Vanderbilt Neonatology, about the new energy of Vanderbilt Clarksville Hospital and how the facility is recruiting physicians. Healio Allergy/Asthma group editorial director Richard Gawel interviewed Mark Rolfsen, MD, Clinical Fellow in the Division of Allergy, Pulmonary and Critical Care Medicine, for a story about his presentation at the American Thoracic Society meeting on metal health outcomes following ICU discharge. Nashville Scene reporter Hannah Herner interviewed James Crowe, MD, Director of the Vanderbilt Center for Antibody Therapeutics, for a story about his efforts to prepare for the next pandemic by isolating antibodies that can neutralize dangerous viruses. Medscape reporter Kathleen Doheny interviewed Neesha Choma, Associate Chief of Staff of Vanderbilt University Hospital, for a story about how hospitals can reduce readmissions.
Scientists measure hidden quantum forces that could power a new generation of pharmaceutical drugs
Researchers invent a laser technique that reveals the hidden forces shaping proteins, advancing a future of precision medicine engineered with quantum precision.
Ohio State–led team secures NSF award to advance to next phase of the National Quantum Virtual Laboratory program
The Ohio State University is strengthening its growing prominence in quantum science, technology, and education with a $4 million, two‑year Phase II design award from the U.S. National Science Foundation (NSF) to advance a national effort focused on next‑generation quantum sensing.The funding is helping to bring together top researchers and ...
Protests at Sen. Collins’s office on Dobbs anniversary
Members of Indivisible Maine and supporters of Graham Platner gathered outside Sen. Susan Collins’ office on Wednesday to criticize her comment that she does “not regret” supporting Justice Brett Kavanaugh’s nomination.
NFL offseason power rankings: No. 30 Arizona Cardinals restart the road to relevance, yet again
J.D. Vance is heir to a more radical politics than Trumpism
…if, of course, he believes what he’s saying
How should European scientists respond to the US AI kill switch?
Earlier in June, Europe’s worst fears of technological dependence were confirmed when the White House ordered the AI firm Anthropic to stop non-US citizens using its leading models. This kill-switch moment crystalised anxieties in Brussels that the continent, lagging the US on the creation of leading-edge AI models, is now a technological of vassal of Washington. The shock has specific implications for European scientists and universities. Some governments are now worried that with AI being integrated into labs, Donald Trump now has his finger hovering over an off switch for European science. “Having restrictions on this tool, it can have an impact on our own research,” said France’s research minister, Philippe Baptiste, at the VivaTech conference in Paris on June 18.Baptiste, himself a former academic, said that colleagues in mathematics had recently warned him they were now cut off from leading-edge US models, risking their work. “This model is not available anymore now because of the US restriction, and for the first time this had an impact on mathematics,” a field where large language models (LLMs) are making a significant contribution, said Baptiste. So, should European scientists avoid relying on US models in the future? Or would this be a self-harming overreaction? And how is AI being used in science, anyway? What happened?On June 12, it emerged that Washington, citing cybersecurity concerns, had ordered Anthropic to stop non-US citizens using two models: Claude Mythos 5, and Claude Fable 5, a version of Mythos but with guardrails to prevent abuse. Anthropic said Washington’s concerns were overblown. But forced to follow the order, yet with no way to check who was using the models, the company suddenly shut down access for everyone, US citizens included. There’s still no agreement on how to restore broad access. But last week, Bloomberg reported that select US companies, and the US government, still had access to Mythos despite the ban, but the EU’s cybersecurity agency Enisa had been shut out. Class division of researchersIn the longer term, access outside the US should be restored, said Marcel Salathé, co-director of the AI centre at the Federal Polytechnic School of Lausanne (EPFL), because a permanent restriction would be financially ruinous to US AI firms. “Even Trump will eventually budge to economic pressure,” he said.However, US AI firms might end up operating rather like banks, doing due diligence on users of their leading-edge AI models, he went on.European scientists are unlikely to fall foul of such checks, he said. But having a Chinese postgraduate in their lab, or doing a type of research the US disapproved of, could potentially result in access being denied. “It will create a sort of class division of researchers,” he said. More than frontier modelsHowever, successfully deploying AI in science is about far more than just having access to leading LLMs such as Mythos.Instead, many science-specific tools, most famously Alphafold, which predicts protein folding structures, require “far less” computing power to train than frontier models, well within the capabilities of European supercomputers, according to a recent analysis by the Arq Foundation, a Brussel-based AI think tank. Instead, tools such as Alphafold are possible because certain fields, like protein folding, weather prediction or astronomy, have large, clean, standardised datasets that can be used to train predictive models. Rather than compute, “data is the central constraint for AI for science,” the report says. For example, a less powerful physics model trained on CERN’s data “will be more valuable than the best model without certain data,” said Bengüsu Özcan, author of the report. European advantage?Europe could therefore steal a march by using its scientific data and infrastructure to create models US digital giants cannot. “They might actually match or go even beyond what these big [US] companies are doing,” said Özcan.Indeed, some European start-ups hope to create automated testing labs to create the kind of standardised data that could speed up the discovery of new materials. Materials scientists say there’s currently too little data to train models. AI scientistsHowever, even if the bottleneck for AI in science is often data, rather than compute, being at the mercy of the US for LLM access could still become a problem for European scientists. A new class of “AI scientists” based on leading LLMs is also emerging, Özcan’s report says.Unlike domain-specific tools like Alphafold, these try to automate day-to-day scientific work, by providing an overarching tool that coordinates specific models to synthesise existing literature, generate hypotheses or run analysis of data. The problem for Europe, however, is that these tools are sometimes based on US leading models. Google Deepmind’s AI Co-Scientist, for example, is built on Google’s Gemini LLM. Systematic failureThese scientific automation tools are still in their early stages, and still exhibit “systematic failures on scientific tasks,” Özcan’s report says. One of the problems is that the messy, day-to-day process of scientific discovery is largely not documented, meaning LLMs don’t have a good source of data to learn how scientists actually work. Meanwhile, some tasks, such as literature synthesis, don’t typically require access to leading edge models.However, the performance of AI scientific assistants could improve as companies such as Google pour resources into developing them. Rely on US“Unfortunately, for scientific assistants, there is not much we can do right now except rely on US frontier AI,” said Antoine Bosselut, a natural language processing expert based at EPFL. Chinese-built open models, which can run on local computers, lessening the risk of a shutdown, are touted as one alternative to US dependence. There’s also Mistral, once seen as Europe’s main AI hope, but the Paris-based company has seen its recent models fall behind in performance. But the Chinese alternatives are generally not as capable as US frontier AI models, said Bosselut, unless paired with fiddly, custom tools that allows them to act as independent agents. “Most scientists do not have the time,” he said. Don’t jump ship yetAlthough the kill switch moment is seen a warning shot for European scientists, it doesn’t mean labs should abandon US AI tools immediately. “I do not think the right response is simply to abandon US-based models and systems under the banner of sovereignty or independence,” said Mattias Björnmalm, secretary general of the Cesaer university association. “That would be an overreaction.”Related articlesEuropean sovereignty in AI requires ‘ugly trade-offs,’ say experts Robotic lab start-up makes case for €500M EU-funded materials testing facilityAI in science: is it useful? Instead, European researchers need to ask themselves whether they’re becoming dependent on technology that could be turned off in Washington, said Özcan. “They might not see this today, but they should really start asking this question,” she said. European researchers need a plan B, said Salathé. “I would recommend to every researcher, very proactively explore alternatives.”Own toolsIn addition, Björnmalm and others want European research institutions to develop their own scientific AI tools.Instead of signing AI deals with US digital giants, European universities should be using this money to create their own models, which may end up being superior for research, said Sabine Leonelli, an expert on the use of AI in science at the Technical University of Munich. “Universities in Europe seem to be happy to sign commercial contracts with US companies on the assumption [their AI tools] are better,” she said. But US frontier LLMs are typically opaque, and have been developed without independent scientific input, she said. “This is not good enough for science.”Last year, Swiss researchers released Apertus, an LLM designed to be completely transparent, from its development methods to its training data. The idea is that this makes scientific tools built on top of the model far more reproducible than with closed, commercial alternatives.“Europe needs more of this: serious capacity-building that gives researchers, universities and companies credible options,” said Björnmalm.
Kustom Entertainment Announces $5.5 Million Divestiture of Legacy Video Solutions Division to Cycurion, Advancing Live Entertainment Focus
Kustom Entertainment announces divestiture of video solutions division to Cycurion, enhancing focus on live events and ticketing.Quiver AI SummaryKustom Entertainment, Inc. announced a binding agreement to sell its legacy video solutions division to Cycurion, Inc., in a deal worth up to $5.5 million, including $1.25 million in cash and a $4.25 million promissory note. The transaction, expected to close in July 2026, will provide Kustom with finan
Moderna Science Day Highlights Expanding Potential of mRNA Platform
Provides broad overview of Company's research and early development programs expected to continue to fuel future growth Highlights validation of T-cell engager modality with mRNA-2808 in multiple myeloma, supporting rapid advancement of second T-cell ...
Folarin Balogun and USMNT Transfer Updates
Hosts Tamerra Griffin and James McNicholas break down a massive six-match World Cup slate as group stages reach their climax. Soccer insider David Ornstein joins the show to discuss the escalating transfer market buzz surrounding USMNT star Folarin Balogun and Tottenham’s Lucas Bergvall. Plus, the team highlights The Athletic’s interactive World Cup Tracker with Jay Harris to map out the complicated qualification pathways for Group A, B, and C. Can the USMNT line up a favorable Round of 32 matchup? Senior Editor Hannah Vanbiber also dives into the debate surrounding Jeremy Doku’s...
CEOs and CIOs Differ Sharply on AI Business Impact and Transformation Success, Protiviti Survey Finds
/PRNewswire/ -- A new Protiviti Global Transformation Survey, The Alignment Advantage in Transformation, finds a significant gap between CEOs and technology...
Ted Cruz’s not-so-secret White House dreams have gotten JD Vance’s attention and annoyed Trump allies
An ice cream social at a supporter’s house. A meet-and-greet with veterans. A roundtable with sheriffs. An evening rally at a sweltering barbecue joint and a winding photo line afterward.
‘Long-term Thinking Is Key To Ensuring Cultural Relevance’: Q’s With Gadget Entertainment Group’s Stefan Wyss
Gadget is one of Switzerland’s longest-standing promoters, having celebrated its 30th anniversary in 2024. In 2020, after already collaborating successfully
19 fours, 6 sixes! Vaibhav Sooryavanshi's younger brother Ashirvad Sooryavanshi hits blistering century
Young cricketer Ashirvad Sooryavanshi, just 10 years old, is making waves with his exceptional batting. He recently smashed a stunning 168 off 119 balls in a practice match, following a debut century. Despite only six months of playing, his aggressive style and big scores are drawing attention, even from his brother Vaibhav, who is currently with the Indian team.
Rubio reassures Gulf allies as US-Iran talks advance
Tehran has already portrayed the deal as a victory
Is The G.O.A.T Debate Over?
Another Messi Masterclass leaves us wondering, is the GOAT debate settled for good? Master & Will debate it, and they launch an all-sport GOAT draft, All that being said about Lionel... could Kylian Mbappé catch the goal record as soon as this World Cup? We're joined by North-East football royalty, Argentine Julio Arca, and French football savant Erik Bielderman.
Senate walks back rebuke of Trump over Iran war
One day after adopting a resolution aimed at removing US military forces from the conflict with Iran, the Senate walked back its rebuke of President Donald Trump’s handling of the war, rejecting an attempt to advance a similar war powers measure.
Senate walks back rebuke of Trump over Iran war
One day after adopting a resolution aimed at removing US military forces from the conflict with Iran, the Senate walked back its rebuke of President Donald Trump’s handling of the war, rejecting an attempt to advance a similar war powers measure.
Sen. Van Hollen: Trump is saying he ‘doesn’t give a damn’ about people who can’t afford housing
Scotland vs Brazil Extended Highlights
Check out the full game highlights between Scotland vs Brazil in the 2026 FIFA World Cup™. Announced by Ian Darke and Landon Donovan.
Scotland vs Brazil Highlights
Check out the full game highlights between Scotland and Brazil in the 2026 FIFA World Cup™. Announced by Ian Darke and Landon Donovan.
'Marcus Alert' begins in Danville and Pittsylvania County for mental health crises
Danville and Pittsylvania County officials have launched the Marcus Alert Program.
Pa. measles cases jump, spread to Northumberland County
An unprecedented measles outbreak in the state has spread to an additional county, the Pennsylvania Department of Health announced Wednesday. Health officials...
Country powerhouse Sara Evans dives into Tulsa Sept. 25
Hard Rock Hotel & Casino Tulsa will welcome multiplatinum country music powerhouse Sara Evans at 8 p.m. Friday, Sept. 25, at Hard Rock Live inside the casino.
Fox News Poll: Looking ahead to America's 250th anniversary
A Fox News survey finds 53% of voters are proud of America and 54% believe the best days are ahead as the nation nears its 250th anniversary.
Pints & Politics with WUNC's Colin Campbell in Pittsboro
To celebrate WUNC's 50th anniversary this year, we're hosting 50 events across North Carolina! Please join us on August 19 at BMC Brewing at The Plant in Pittsboro for Pints & Politics with WUNC Capitol Bureau Chief Colin Campbell! The event kicks off at 6 p.m.We'll chat about all things North Carolina politics, and your first pint will be on BMC Brewing in a special WUNC 50th anniversary pint glass! This event is free and open to the public, but an RSVP is encouraged as space is limited. Please RSVP at the link below to let us know if you are planning to join us. You can also submit a question for Colin in advance when you sign up to attend. We hope to see you soon!> RSVP Here
4 Takeaways From Canada's Group-Stage Finale Loss To Switzerland
Both teams advance to the World Cup knockout round, but one clearly looks better than the other.
Even in Defeat, a Democrat Showed the Upside of Angering the A.I. Industry
Alex Bores’s close loss in New York could pave the way for other Democrats to take political advantage of being attacked by the increasingly unpopular A.I. industry.
Perks of the job: Save on entertainment and essentials with BenefitHub
State of Colorado employees have access to a wide-ranging corporate discount marketplace, and those eligible for benefits at Metropolitan State University of Denver can take advantage of them with their University email. The State of Colorado BenefitHub offers deals on thousands of products, ranging from vacation and event tickets to insurance and other essential services. […]
Cityblock in talks to buy fellow General Catalyst-backed startup Homeward Health
Cityblock Health in talks to acquire General Catalyst-backed rural care startup Homeward, expanding into Medicare Advantage, source says.
Riot now lets you enable its anti-cheat when you want to
You’ll be able to turn on Vanguard just while you’re playing.
Caravan of Care Brings Free Health Services to Goodwill on Dearborn
From dental cleanings to ORCA card help, Evergreen Goodwill's outdoor resource fair on Dearborn aims to meet community needs in one place.
New York primaries: Clean sweep as 3 candidates endorsed by Mamdani win
New York Mayor Zohran Mamdani flexed his political muscle Tuesday, getting a clean sweep as his three endorsed congressional candidates advanced to November's general election.
Program Director Shares How Articulation Agreements Benefit Meredith Pre-health Post-Baccalaureate Students
Karthik Aghoram, director of Meredith’s Pre-health Post-Baccalaureate Program, recently spoke with Inspira Advantage about the program’s articulation agreements and why they are valuable for students seeking careers in health care.
FSU computational scientist helps advance targeted drug-delivery systems using coding, modeling
A Florida State University computational scientist is paving the way for future medical breakthroughs by developing mathematical models and simulations to
Men’s Health: Caring for the Body, Mind and Spirit
FORT POLK, La. — Seeking help is often viewed as a vulnerability in military culture, but healthcare providers at Bayne-Jones Army Community Hospital are reframing it as a tactical strength. In observance of Men's Health Month, a BJACH family physician, a mental health provider and the hospital chaplain have partnered to deliver a unified message: peak military readiness requires actively maintaining the body, mind and spirit. From utilizing routine screenings to leveraging physical discipline to build mental resilience and cultivating a strong spiritual community, the team outlines actionable steps to overcome the physical, emotional and isolation barriers that uniquely impact men.
Abortion rights fight underscores key themes in Maine’s U.S. Senate race
Four years ago today, the U.S. Supreme Court overturned Roe vs. Wade. In the majority of that decision was Justice Brett Kavanaugh, who Republican U.S. Sen. Susan Collins of Maine had voted to confirm after he had told her the landmark decision was “settled law.”
Penn LDI and Monogram Health Announce Second Research Partnership
The University of Pennsylvania’s Leonard Davis Institute of Health Economics and Monogram Health have launched a second research initiative, backed by a $600,000 gift, to improve care for patients…
Inside the “simple job” in government Platner held before Senate run
Platner once said the office of harbormaster of Sullivan, Maine, might've been his ceiling in politics.
Ari Emanuel's Mari In Talks To Buy Theater Giant ATG Entertainment
Mari, the events company founded last year by Ari Emanuel, is in advanced talks to acquire West End and Broadway theater giant ATG Entertainment.
Science museum brings soccer tech to World Cup fans
Soccer & Technology from the FIFA Museum, in its North American debut in Vancouver, has drawn hundreds of fans to Science World to study the game's evolution as organisers aim to accelerate soccer's growth in ice hockey-mad Canada.
State advances over four hundred projects in bid for Rural Health Transformation Program funding
The state received about 1800 letters of interest from organizations, and those chosen are advancing to the application phase, or are getting grants for project planning.
Reflecting Pool faces fresh scrutiny over vandalism claims and duck deaths
Trump pledged to beautify the century-old Reflecting Pool ahead of the country's 250th anniversary
Flagship Pioneering and Lean Business Services Company Announce Collaboration to Advance Healthcare Innovation and AI-Enabled Biomedical Research in Saudi Arabia
/PRNewswire/ -- Flagship Pioneering, the scientific innovation company behind Moderna, Generate Biomedicines, and more than 100 other life sciences ventures,...
Ari Emanuel Is in Talks to Buy ATG Entertainment, FT Reports
Hollywood superagent Ari Emanuel is in advanced talks to buy the theater group ATG Entertainment Ltd. for £4.5 billion ($5.9 billion), the Financial Times reported.
President Trump tells politician to 'run up here' during speech
President Donald Trump introduces Pennsylvania Congressman Ryan Mackenzie at a rally.
Tickets for top entertainment events at Scotts Bluff Co. Fair go on sale Wednesday
Tickets for the ‘big three’ of the nightly entertainment at the Scotts Bluff County go on sale Wednesday morning. Starting at 9 a.m., you can get your advance tickets for the Truck and Tractor Pull…
Trump touts U.S. economy and oil prices in a midterm pitch in Pennsylvania
The president told supporters in a key swing district that oil is coming down and prices will follow as cost-of-living issues are top of mind for voters ahead of November.
Science of baseball event brings Evansville Otters to CMOE
Visitors learned about baseball science at CMOE with Evansville Otters players
Trump’s midterm liabilities on display in visit to toss-up district
A campaign-style appearance in Pennsylvania revealed the delicate position of Republicans facing tough reelection fights. They still need Trump’s voters, but are increasingly cautious about embracing him too closely.
Trump touts falling oil prices, economy at Pennsylvania rally
The president spoke at a Mack Trucks factory in Macungie on Tuesday
Trump touts falling oil prices, economy at Pennsylvania rally
The president spoke at a Mack Trucks factory in Macungie on Tuesday
Trump touts falling oil prices, economy at Pennsylvania rally
The president spoke at a Mack Trucks factory in Macungie on Tuesday
Landmark housing bill advances in Congress with bipartisan support
Measures to provide federal funding for housing production in big cities could be particularly significant to California.
Marathon's First PVE Mode Launches Next Month And Sounds Great
I want to play Vault Breaker right now, but have to wait until July 21
Tickets for top entertainment events at Scotts Bluff Co. Fair go on sale Wednesday
Tickets for the ‘big three’ of the nightly entertainment at the Scotts Bluff County go on sale Wednesday morning. Starting at 9 a.m., you can get your advance tickets for the Truck and Tractor Pull…
FedEx posts strong earnings results in last quarter with freight business
FedEx posted strong fiscal fourth quarter earnings on Tuesday in the company's last quarter that included the freight business before its spin-off.
A lot of science policy doesn’t fail, it just never makes it through the system
I think that it all comes down to organization, making sure that you have a plan for how your policies are going to be implemented," said Cole Donovan.
Advancing pediatric health care with AI
A new national hub in D.C. is turning pediatric AI research into clinical workflows.
2026 World Cup Bracket, Standings, Projections: USA in Round of 32, Who Else Might Advance?
Track the 2026 FIFA World Cup bracket with live standings and Round of 32 projections. See where Team USA stands and who's on track to advance.
Vanderbilt Health is first US site for advanced clinical testing platform
Part of the cobas pro integrated solutions produced by Roche, the platform will speed up laboratory testing and improve patient care.
Offworld Space Biology: Setting Up The Life Science Glovebox
Bioengineering cartilage tissues and manufacturing advanced materials kicked off the week aboard the International Space Station
Pivot Fellow Natasha Blitvic Brings Math to Marine Microbiology
Pivot Fellow Natasha Blitvic Brings Math to Marine Microbiology on Simons Foundation
Vanderbilt Health lands three of 35 Susan G. Komen research grants
Komen is the largest nonprofit funder of breast cancer research outside of the U.S. government, having invested more than $1.1 billion in research since its founding.
Hodder Tugboat acquires Seaspan's towing business
Hodder Tugboat Co. Ltd., Richmond, British Columbia, has finalized its purchase of the legacy chip and hog fuel barge division of Seaspan Marine, North Vancouver, British Columbia, the companies annou
Exxon can sue Cuba over property confiscated in 1960, Supreme Court rules
The Supreme Court on Tuesday allowed Exxon Mobil to sue state-owned oil companies in Cuba over the confiscation of property that occurred after Fidel Castro’s regime seized power nearly seven decades ago, letting the lawsuit proceed at a time when President Donald Trump has taken an aggressive stance toward Havana.
RBC AND CANUCKS SPORTS & ENTERTAINMENT (CSE) ANNOUNCE MULTI-YEAR PARTNERSHIP; RBC LOGO TO BE FEATURED ON VANCOUVER CANUCKS HOME JERSEYS
RBC expands commitment to sports, entertainment and community by connecting CSE fans to enhanced experiences, including exclusive benefits for RBC clients
Advances in materials science are helping unlock secrets of nanomaterials
New instruments on the horizon promise the most precise tools yet to study and experiment on the smallest and most complex materials ever manufactured. In a paper published in the journal Nature Materials, ...
Meta announces new smart glasses starting at $299, as Zuckerberg keeps pushing wearables
Meta executives have said they see the lightweight smart glasses as a step towards a more advanced device that includes screens in the lenses.
Renowned Life Science Leader Dr. Gino Martini Joins KIFFIK Biomedical as Chief Scientific Officer
Dr. Martini brings extensive industry, government, and academic expertise to KIFFIK Biomedical, strengthening translational science capabilities as the company advances its K-EXP™ platform and expands access to interstitial fluid (ISF)
A look at Elevance Health's push to streamline clinical reviews
Elevance Health is making strides toward a simpler and more streamlined clinical review process through its Health OS platform. | Elevance Health is making strides toward a simpler and more streamlined clinical review process through its Health OS platform.
"This is going to be a niche device" – Analysts react to the $1,000+ Steam Machine price reveal
Mat Piscatella, Joost van Dreunen, Manu Rosier, and Piers Harding-Rolls offer their thoughts on the price implications for Project Helix and PS6
Jon Stewart blames JD Vance's Iran negotiations failure on a nose-picking incident: 'Classic diplomatic faux pas'
'The Daily Show' host Jon Stewart blames the failure of Vice President JD Vance's Iran negotiations on a nose-picking incident seen in viral video: 'Classic diplomatic faux pas.'
Eight downtown Ukiah businesses vandalized, business owner helps neighbor all night
“Gaping holes” in Ukiah businesses after windows smashed at 3 a.m., neighbor helps past sunrise.
Norway vs Senegal Extended Highlights
Check out the full game highlights between Norway and Senegal in the 2026 FIFA World Cup™. Announced by Ian Darke and Landon Donovan.
As Vance Leads Iran Negotiations, Trump Creates Disruptions in His Path
Vice President JD Vance is in a politically precarious spot.
Experts on history, politics reflect on U.S. 250th birthday milestone
As our nation’s celebration of its 250th birthday approaches, experts in history and political science at Virginia Tech can provide perspectives on how far the United States of America has advanced since its founding and the issues that will influence where it goes next.
Virginia legislators advance $205 billion budget including new tax on data centers
Virginia legislators approved a two-year, $205 billion budget proposal to fund healthcare and public education, provide 4% teacher raises and a 3.5% pay bump to state employees, establish a retail weed marketplace and hedge against decreased federal dollars.
The Carriage House at Paper Mill Playhouse Launches Summer 2026 Entertainment Series
(MILLBURN, NJ) -- The F.M. Kirby Carriage House at Paper Mill Playhouse announces its inaugural Summer Entertainment Series, introducing acclaimed Broadway and cabaret artists Evan Tyrone Martin (New York City Center's The Wild Party) and Annie Hägg (Giant) to lead an expanded lineup of live entertainment throughout July and August at the newly refurbished restaurant and event space.
Sen. Dan Sullivan’s same-name challenger sues to stay on ballot
A man with the same name and party affiliation as Alaska Republican US Sen. Dan Sullivan on Monday challenged a decision by a top state elections official to disqualify his candidacy and remove him from the August primary ballot.