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People visiting Japan are too scared of breaking rules, says local
As a resident of Japan, I've seen tourists to my country scared to break rules or make etiquette mistakes. But respect matters more than perfection.
Motorola announces Moto Pad and next-gen Moto G Stylus
They'll be available starting April 16 and April 30, respectively.
Arsenal’s Gabriel, Declan Rice, Leandro Trossard to return vs Sporting CP
The trio were among 11 Arsenal players that withdrew from their respective international squads over the March break.
CAA Softball Weekly Awards
RICHMOND, Va. – UNCW’s Allison Corbin and Hofstra’s Ryleigh Smith captured CAA Player and Rookie of the Week honors, respectively, while a pair of complete-game shutouts from both the Pride’s Emma Falen and Campbell’s Katelyn Hubley split Pitcher of the Week recognition, respectively, on Monday.
Trump's respect for King Charles possibly quashed desire to annex Canada, says royal commentator
An upcoming book authored by a prominent royal commentator says U.S. President Donald Trump was primarily interested in annexing Canadian territory just above the U.S. border — and his respect for King Charles may have quashed his interest.
A nonpartisan California news site draws worldwide audience
Jack Kavanagh's website, Rough & Tumble, has a worldwide audience despite — or perhaps because of — its lack of flash, commentary and snark. It's a well-respected compendium of politics and policy.
Sports Illustrated is attempting a rebound after layoffs
One of the most respected brand names in journalism is now generating revenue through streaming TV, branded events, ticket services, and international editions.
Politics of Black hair: why grooming rules are under scrutiny across the diaspora
From schools in Ghana to workplaces in Britain, underpinned by the colonial roots of ‘respectability’, conversations around natural hairstyle persist
NBA, NHL teams told Main Street sports network will end operations
Main Street Sports Group, the flailing regional sports network, has informed NBA and NHL teams it will cease operations at end of their respective seasons.
NBA, NHL teams told Main Street sports network will end operations
Main Street Sports Group, the flailing regional sports network, has informed NBA and NHL teams it will cease operations at end of their respective seasons.
Tampa meteorologist, beloved community advocate and respected mentor Andy Johnson passes
Johnson is survived by his husband, veteran Tampa Bay area Democratic political consultant Bryan Farris, and the couple's loving family.
Smiley: Let's return to a politics of respect, compassion
Providence Mayor Brett P. Smiley reflects on political division, using a recent mural controversy as an example of growing hatred.
Morning Sports: April 3, 2026
Sheridan/Johnson County HS Spring Sports: Most of the Wyoming High School sports action took place during the mid-week to avoid conflicting with the Easter Holiday weekend. On the soccer field, the Sheridan boys and girls both won at Worland yesterday, by scores of 10-1 and 5-nil respectively. Buffalo split games at Powell. The Bison won […]
CDC releases report on flu, COVID-19 vaccination coverage for health care workers for 2024-25 respiratory season
Flu and COVID-19 vaccination rates among all health care workers for the 2024-25 respiratory virus season was 76.3% and 40.2%, respectively, according to a Centers for Disease Control and Prevention report released April 2.
2026 World Cup Group Stage Odds: Spain, Argentina Heavily Favored
The 2026 World Cup groups are set. See the odds for which countries are favored to win their respective groups.
Haleiwa open for business as North Shore storm recovery continues
While people are urged to stay away from impacted neighborhoods, local business leaders stressed that Haleiwa town is open and that respectful support can help the community recover.
CAA Softball Weekly Awards
RICHMOND, Va. – Hofstra’s Dahlia Palacio and UNCW’s Cassidy Relay split CAA Player of the Week honors following incredible offensive performances, while the Pride’s Emma Falen and Campbell’s Katelyn Hubley garnered Pitcher and Rookie of the Week, respectively, on Monday.
US: Rights-Respecting Approaches to Mental Health Crisis
Communities throughout the country are developing alternative models of mental health crisis response.
“Self-Determination is the Pathway to Liberation”
The 66-page report, “‘Self-Determination is the Pathway to Liberation’: Alternative Mental Health Crisis Response in the United States,” identifies key elements of rights-respecting responses to mental health crises and explores how alternative mental health crisis response programs have carried out these approaches in practice. Many of these models share core elements, including promoting individual autonomy, providing voluntary support rather than mandating compliance, and avoiding unnecessary law enforcement involvement.
Even the 'Avatar' Fighting Game Is Disrespecting 'Legend of Korra'
The roster for 'Avatar Legends' doesn't play favorites, but at launch, it doesn't really care for 'Legend of Korra.'
Opinion: What happened to the Republican Party of Ronald Reagan?
What we see today is not the Republican Party of Ronald Reagan, George H.W. Bush, George W. Bush, John McCain or other respected Republicans.
AI-industry super PACs are mostly winning so far
All but one candidate backed by AI-industry super PACs have moved forward in their respective elections this year.
New Congressional bill targets sports team relocations
More than 40 years after the Colts left Baltimore for Indianapolis like thieves in the night, those in a profession that enjoys nearly the same level of respect are trying to prevent it from happening again.
Bucks G Kevin Porter Jr. pledges to beat Bam Adebayo's 83-point game 'for the respect of Kobe'
Asking Eric: I love my brother, but I don’t agree with his politics
Dear Eric: I am questioning my decision on whether to go to my brother’s daughter‘s wedding. They live two states away, and I have not seen them for a few years. I love my brother, but I don’t respect or agree with his political choices and…
Women's game needs more respect
Chelsea manager Sonia Bompastor says the women's game needs "more respect" after her side have a goal controversially disallowed in their Women's Champions League quarter-final first leg against Arsenal.
Marathon has sold 1.2M copies across Steam, PS5, and Xbox
Alinea Analytics estimates show that Marathon has generated gross revenues of $55M via 1.2M copies sold on Steam, PS5, and Xbox: Looking at the split between Steam, PS5, and Xbox, Steam is clearly the main platform for Marathon, accounting for a little under 70% of the audience (800K copies sold). Meanwhile, PS5 takes about 19% (217K) and Xbox (including console, PC, and cloud) accounts for a bit over 11% or 133K. Marathon is technically a first-party Sony title, so seeing the home console struggle to break 20% of the volume is a notable data point for the ongoing platform-agnostic debate. PlayStation Studios online games will almost certainly continue being multiplatform (despite Sony reportedly pulling back on PC releases). Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe As for Marathon, the consensus among hardcore players who pushed through the awkward onboarding phase – myself included – is that it’s fantastic. The gunplay, aesthetic, and presentation are among the best in the shooter genre. A great game doesn’t always equal an immediate hit, though, as shown by our estimates. Things are looking lukewarm right now. But this might be one of those marathon-not-a-sprint situations. Had to, didn’t I? Why wasn’t Marathon a hit on the same level as Arc Raiders? One topic that came up in a lot of conversations at GDC this year was why Marathon hasn’t hit the same stratosphere as Arc Raiders. On paper, they’re both extraction shooters, and Marathon has the Bungie pedigree – the house that built the gold standard for gunplay in Halo and Destiny. Marathon’s neon-futuristic aesthetic also distinguishes itself from the gritty realism of Tarkov or the post-apocalyptic hope of ARC Raiders. But vibes can only get you so far for first impressions if the onboarding feels like a brick wall. Marathon is a sweaty PvP-focused experience with a first-time user experience and UI that I can only describe as dreadful. Players are dropped into a complex ecosystem where the UI, though visually striking, is functionally uninformative, forcing users to manually hover over nondescript, identical icons just to identify basic gear or weapon mods. This lack of clarity is compounded by punishing mechanics like a severe heat gauge for movement and a scarcity of vital resources, all without a clear tutorial or a low-stakes mode to learn the ropes. Most people – even top streamers and veteran shooter players – have no idea what’s going on in Marathon at first. Arc is on the complete other end of the spectrum. As we covered here and here, Arc Raiders offers a more collaborative, approachable loop where players often work together toward shared goals. And the objectives are instantly clear. To many players, this contrast only emphasised Marathon’s issues, especially during the testing period. Players understand the Arc Raiders loop within 30 minutes, while Marathon acts as a massive filter, chewing up newcomers and spitting them out before they can experience the depth of Bungie’s signature gunplay. What I’m getting at here is that the poor first-time user experience of Marathon’s Server Slam likely stifled launch sales, while the opposite was true for Arc. Let’s look at the pre-launch copies sold for each game during their respective Server Slams (launch-aligned) : Looking at the trajectory: Arc Raiders saw a massive 80% jump in copies sold during its three-day Server Slam (day -13 to -11). Players jumped in, realised the water was fine, and immediately opened their wallets. Marathon, meanwhile, saw a 49% increase in the four days following its Slam (Day -7 to -3). At the time of each game’s respective launch, Arc Raiders had nearly double the Steam footprint of Marathon – and word of mouth only continued to grow. Bungie could have had more time to fix the onboarding process had the beta happened earlier. But Marathon launched three days after the beta finished. These factors limited the launch sales quite a bit, I reckon. Marathon has found a niche audience, though Despite the friction-heavy start, the data suggests that those who survived Marathon’s onboarding are loving life. We’ve been tracking cross-platform DAUs, and while there’s the expected post-launch leakage, many players are sticking with it. After peaking at 478K total DAUs on its first Saturday, Marathon has settled into a respectable rhythm, holding 345K DAUs as of yesterday and averaging 380K DAUs across the weekend. Steam continues to do the heavy lifting here, consistently accounting for the lion’s share of the daily players. Players have been putting in the hours, too: On Steam, Marathon’s average playtime has climbed to 27.8 hours, significantly outpacing the console averages on PS5 (16.5h) and Xbox (17.3h). Even more telling than the averages: 22% of the Steam audience has surged past the 50-hour mark, and nearly 7% have already logged over 100 hours. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe This data suggests that once the Bungie magic clicks, it hooks players deeper than the average extraction shooter. There’s also started to be a shift in the game’s discourse. Marathon launched as one of those games that’s cool to hate. But as Marathon’s 100-hour club grows, we’re seeing conversations around its mechanical merit outweigh the negativity. Several high-profile creators, who were initially vocal critics, have spent the last week coming around on the mechanical depth of the endgame. It’s a subtle but positive signal; the hate train is losing steam, and a new narrative about the game is emerging. Bungie faithfuls unite Another interesting metric in Marathon’s first few weeks is who, exactly, is playing. Bungie leans heavily on its prestige as the “makers of Halo and Destiny,” in its marketing, and that message has clearly hit the mark. On Steam, the gravity (hammer) of Bungie’s previous work is unavoidable. A staggering 78.2% of Marathon players also played Destiny 2. The trend carries across other platforms, with 74.2% of PS5 players and 82.7% of Xbox players also having played Destiny 2. The Halo legacy lives on, it seems. More on that in a bit. While Destiny 2 went free to play, these numbers still represent a high-intent migration of a fanbase that trusts Bungie’s specific brand of kinetic gunplay and cryptic world-building. The Xbox data adds another layer of legacy. About 85.7% of Marathon players on Xbox have played Halo Infinite, while over half of the Steam audience has spent time in Halo Infinite and 36.1% in the Master Chief Collection (a paid collection of the old Bungie-made legacy games). Interestingly, we see a 55.9% overlap with ARC Raiders on Steam. Overlap is even higher there on PlayStation (60.5%) and Xbox (66.5%). And there’s also significant crossover with Helldivers 2 on all platforms, too. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe Bungie has found some of its fans with Marathon, and the challenge now is keeping this engaged in a high-stakes PvP environment when they’ve spent the last decade primarily enjoying the power fantasies of PvE. On that note… Go the full 26 miles? Or cut and run? Time for some could’ve, should’ve, would’ve. These things would have improved Marathon’s performance at launch: A more robust onboarding process, perhaps in the form of a short single-player/PvE campaign. We know Bungie fans love this stuff. A traditional arena-based mode akin to Destiny’s Crucible could have been a bridge for the cautious players who’d have been otherwise deterred by the Server Slam. It’s also a great palate cleanser after getting merked. Introducing a dedicated PvE environment would have similarly diversified the conversation and lowered the barrier for the Bungie faithful who found the pure PvP extraction loop too abrasive. PvE is safer than PvP these days. There’s an argument that a thin PvE mode would have just felt like a budget Destiny, potentially hurting the brand more. But given how dire the FTUE is, I think it would have been a net positive. Any kind of tutorialised loop that demystifies the stakes, really. While there is merit in a studio sticking firmly to a singular creative vision, and going all in on the hardcore extraction loop. Less forgiving is the technical reality is that the user interface and first-time user experience (FTUE) were not at a commercial standard for launch. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe In a landscape where player time is oversaturated and the most contested currency, a flawed FTUE is a critical failure point. But it’s not all doom and gloom, as Marathon has an incredible, unique gameplay loop, suggesting that financial success is still attainable if Bungie can pivot effectively. Bungie and PlayStation now face a difficult strategic crossroads, though – one within a challenging games market. They could: Double down on Marathon with a long-term Rainbow Six Siege- or No Man’s Sky-style recovery plan, which is something I heard Last Stand Media’s Chris Maldonado mention last week. While this could be a sunk-cost fallacy in action, it could eventually yield the audience the game’s mechanical depth deserves. Shift focus toward the inevitable Destiny 3 or another project, mitigating the escalating opportunity cost and cutting their losses, so to speak. Doing both is an expensive proposition, given the high overhead and burn rate of operating out of Bellevue, Washington. With Sony recently demonstrating a lower threshold for underperforming studios and projects, the margin for error has vanished. Whatever happens, the next six months will determine whether Marathon becomes a cornerstone of Sony’s live-service portfolio or a cautionary tale of vision exceeding accessibility. I’m hoping it’s the former, because Marathon rocks. As always, hit subscribe to get updates on Marathon and other relevant games. Subscribe Want to get your hands on our data for yourself – for free? We’re offering a free trial of our platform for games companies. Send us a message here, or reply to this email, and we’ll set you up. The last word Reply to this email – or reach out here – if you have any feedback for the newsletter – or want to request a game for us to cover. [Alinea Analytics boasts the most accurate PC and console estimates in the business. Game makers use our platform to understand their audience, keep an eye on the competition, monitor sales trends, and spot new opportunities. We equip game studios and financial institutions with accurate data and the confidence to make smarter, data-driven decisions. Want to talk about all things games market data? We’d love to chat!]
Playoff-bound Wild, Lightning out to improve positioning
The Minnesota Wild and Tampa Bay Lightning, two powerhouses preparing for the playoffs in their respective conferences, will complete their two-game season series in Tuesday night's matchup in the Sunshine State.
Mum on his own replacement, Bennet disrespects voters
U.S. Sen. Michael Bennet is playing an arrogant game of hide-and-seek with Colorado voters as he seeks to abandon his Senate seat to become governor. Bennet insists that if he is elected governor in November, he will wait until he is inaugurated in January 2027 before he resigns from the Senate so he can unilaterally […]
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Video: Business Report Hall of Fame honoree Bob Greer
A respected figure in the insurance and banking industries, Robert Stephenson “Bob” Greer Jr. made an indelible impact on Baton Rouge, combining an abiding love for his hometown with ambitious ideas on how to make it better. Greer was recently named a 2026 Hall of Fame laureate (posthumous) by Business Report. Watch the video of Bob […]
Red-hot teams clash when Hurricanes visit Blue Jackets
Andrei Svechnikov and Sebastian Aho look to continue their respective strong play on Tuesday as the Carolina Hurricanes visit the streaking Columbus Blue Jackets.
China woman uses AI-made man to lecture on respecting science, rejecting superstition
Non-existent retired professor who ‘lectures’ on parent-child relationships gathers online support from 200,000 followers.
Billy Crystal Delivers Emotional Tribute To Rob Reiner At The Oscars: The ‘Loss Is Immeasurable’
The “When Harry Met Sally” star was later joined by a slate of actors paying respects to the legendary director at the 98th Academy Awards.
Is Academy Sports and Outdoors, Inc. (ASO) A Good Stock To Buy?
Is ASO a good stock to buy? We came across a bullish thesis on Academy Sports and Outdoors, Inc. on Valueinvestorsclub.com by andreas947. In this article, we will summarize the bulls’ thesis on ASO. Academy Sports and Outdoors, Inc.’s share was trading at $55.50 as of March 12th. ASO’s trailing and forward P/E were 10.20 and 8.51 respectively […]
Linux Finally Catches Up to Windows with a Game-Changing Performance Feature
For years, the Linux kernel’s scheduler has been world‑class at balancing loads, yet it missed a crucial, cache‑aware instinct. In modern multi‑core systems, that gap can turn into measurable latency, especially when threads bounce between cores that don’t share the same cache. A new upstream feature, often called Cache Aware Scheduling, is now set to change that equation. A cache‑savvy scheduler arrives At the heart of any OS, the scheduler decides which thread runs where and for how long. In modern CPUs, small private caches (L1 and L2) sit beside each core, while a larger Last Level Cache (LLC, typically L3) is shared among groups of cores. When a task migrates across LLC boundaries, its warm data may vanish from the cache, forcing slower trips to main memory. Cache Aware Scheduling keeps related tasks close to their shared LLC, reducing destructive migrations. By respecting cache topology, the kernel minimizes cold‑start penalties and preserves locality that many workloads desperately need. The result is less thrashing, fewer memory stalls, and more consistent throughput. "Keep tasks close to their data, and the system will keep performance close to its peak." Why this narrows the Windows gap Windows has long leaned on topology‑aware, cache‑sensitive heuristics, especially since the Windows 10 era. That advantage helped Microsoft handle hybrid designs with P‑cores and E‑cores, plus complex cluster and NUMA layouts. With cache awareness integrated upstream, Linux brings parity to this vital dimension, without sacrificing its trademark flexibility. The Linux approach remains deeply configurable, reflecting the ecosystem’s breadth across servers, desktops, and embedded devices. It layers atop existing NUMA‑balancing and energy‑aware logic, refining placement rather than reinventing the wheel. Crucially, it aligns scheduling with the hardware’s real shape, not just with abstract CPU counts. Real‑world gains and who benefits Early tests on Intel Sapphire Rapids platforms point to gains in the 30–45% range for select workloads. Those wins appear in cache‑sensitive tasks like in‑memory analytics, high‑thread compilation, and microservices with tight working‑sets. Games and latency‑bound engines can also feel steadier frame‑times, especially when threads share hot assets. The benefits extend to AMD’s 3D V‑Cache parts, where keeping threads near enlarged cache slices prevents needless misses. Hybrid x86 designs with performance and efficiency cores further profit when cache and core roles are scheduled in concert. Even handhelds running SteamOS can squeeze more out of limited power, translating cache locality into smoother play. Key advantages include: Lower end‑to‑end latency Fewer expensive misses to RAM Better multi‑socket and NUMA behavior Improved energy efficiency More predictable QoS under mixed loads Stronger scaling on dense servers Caveats, tuning, and rollout No scheduler change is purely free, and trade‑offs still exist. Favoring locality can reduce cross‑cluster balance if limits are set too tight. Likewise, fairness and utilization must remain healthy, especially under heterogeneous, bursty workloads. Linux’s implementation is designed to be measured and tunable, not a blunt instrument. It cooperates with energy‑aware scheduling for mobile efficiency, and with NUMA‑balancers on big iron. Expect architecture‑specific refinements as vendors surface richer topology hints and cache‑sharing maps. Upstream integration has begun, with broad distribution adoption likely over the next cycles. Many users will encounter the change through standard kernel updates in 2025–2026, depending on distro cadence. Server‑class kernels may enable or tune it sooner for targeted fleets where cache locality is money in the bank. How to think about performance impact Cache Aware Scheduling amplifies gains when your workload is both CPU‑bound and cache‑sensitive. Think tight inner loops, hot code paths, and datasets that fit snugly in shared LLC. It’s less dramatic for I/O‑bound services or memory‑hungry tasks that blow past cache capacity. Still, even modest locality improvements often translate into smoother tail‑latency, which is where user experience and SLAs typically break. Developers can further help by pinning related threads, batching work, and aligning data to reduce cross‑cluster chatter. The scheduler’s new awareness works best when applications expose good hints. The bottom line By understanding and honoring cache topology, Linux removes a subtle yet costly bottleneck. The kernel’s smarter placement keeps hot data hot and work near where it belongs. That narrows a long‑standing gap with Windows, while preserving the openness and tunability Linux champions. For gamers, creators, and operators, the payoff is practical: more consistent frames, faster builds, and snappier services. For the ecosystem, it’s another step toward hardware‑savvy scheduling that turns transistor complexity into real‑world speed. And for Linux itself, it’s a timely upgrade that matches today’s silicon with tomorrow’s expectations.
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Transcript, videos: Louisville talks after topping SMU
Transcript: PAT KELSEY: A lot of credit to SMU. Andy is a really good coach. We played down at their place a couple weeks ago, and they just kicked the crap out of us. So ton of respect for them. Their offensive firepower is as good as anybody in the country. Proud of our guys. […]
Mental health solutions for the digital age
Ask the digital natives of Gen Z about the source of their biggest mental health challenges, and most will say social media and AI.Several of the nearly 400 guests at the third annual Gen Z Wellness Summit, presented by the Friends of Semel Teen Advisory Council at UCLA on March 8, explicitly named the endless stream of content on their phones as serious stressors. “Everybody is addicted to (Tik Tok) as if they were addicted to substances,” said Jantin Asmar, 17, a senior at Virtual Academy in Antelope Valley. “We’re always chasing that dopamine. We’re expecting that dopamine rush and it’s really decaying our interactions with others.” High school student Jantin Asmar was among nearly 400 people who attended the third annual Gen Z Wellness Summit. (Photo by Sandy Cohen) Even young teens feel pressure to be on social media constantly, both to consume content and collect “likes,” said 13-year-olds Chloe and Sophia, both students at Brentwood School. “Everyone’s always on, and you miss stuff if you’re not on it,” Chloe said, adding that social media’s emphasis on appearances is leading to eating disorders: “That’s a big thing for our generation.”The incessant influx of images and updates creates expectations that “weigh teenagers down,” said Linda Kou, 16, a junior at San Gabriel High School.Even though digital spaces allow people to connect with others beyond their immediate surroundings, it doesn’t always translate to real-life community, said Kelah Morgan, 17, a senior at Animo South Los Angeles Charter High School. High school students Kelah Morgan, left, and Linda Kou, shared about the challenges presented by social media. (Photo by Sandy Cohen) “Even if you see people saying that they relate to you online, it might be hard to find people in your personal life who you see every day who you feel comfortable enough to say, ‘You see me online, but this is me in real life and what I’m actually going through,’” she said.Solutions for our digital timesThe Gen Z Wellness Summit was intentionally designed as a free, in-person gathering where young people interested in mental health from across the southland could meet in person. “Peer support is the most important element of maintaining our mental health in community,” said Helena Hansen, MD, PhD, director of UCLA’s Semel Institute for Neuroscience and Human Behavior.Keynote speakers at the summit addressed AI, social connection and self-empowerment, while breakout sessions included discussions about eating disorders, dating, substance use, phone detox and breathwork. Here are some of the day’s top takeaways:Beware of FOPO: Scott Barry Kaufman, PhD, a psychology professor at Columbia University, said that rather than FOMO, or fear of missing out, we ought to be more aware of FOPO: fear of people’s opinions. “Just think about how much your FOPO might be holding you back in your life,” Dr. Kaufman said. “And just that inner contemplation should be enough for you to change your life, because there’s so many things we don’t go after because we have debilitating FOPO.”We don’t need to feel like we’re the best – or what he called “narcissistic self-esteem” – but it’s helpful to acknowledge our own worth, recognize our good qualities and develop self-belief in the skills and talents we’ve cultivated. When we have that – dignity and self-respect, without needing everyone to like us – FOPO is less of a concern.Self-reflection is most effective in community: “When we try to self-reflect alone, we sometimes ruminate,” said Ira Bedzow, PhD, executive director of the Emory University Purpose Project. “But when we self-reflect with people that we trust … (it) allows us to hold ourselves accountable to different ways of seeing and different ways of hearing and different ways of being.”Opening up about our experiences and listening to others are skills we can develop, Dr. Bedzow said.He invited students to participate in what he called a “fishbowl exercise,” where four students sat in a small circle, surrounded by a dozen or so students forming a larger circle. Those in the inner circle answered such questions as: “What stops you from being you today?” and “What helps you feel most like you?”Within minutes, the group in the small circle (the fishbowl), were sharing intimately about their life challenges as those in the outer circle nodded in understanding.After the exercise, one participant said, “I felt like I wasn’t alone, that it wasn’t just me who feels that way.”Another remarked on how “personal” it felt to share face-to-face with others, even strangers.Don’t let AI crush your creativity: Theoretical neuroscientist Vivienne Ming, PhD, has been studying artificial intelligence for more than 20 years. And while she said “it’s reasonable to be concerned” about the fast-growing technology, it can also help humans become better problem-solvers when used strategically.“The smartest thing on the planet today are humans and machines working together creatively,” Dr. Ming said. “What gets more valuable in humans as machines get smarter? Our ability to explore the unknown.“Your unique voice is literally your value to the world … but most of us for most of our lives have been taught to not be unique,” she continued. “Be your own person. Celebrate being different. It is genuinely, measurably, truly valuable.”In a breakout session called “Phone Detox? IYKYK: Living Your Story IRL” led by Don Grant, PhD, students shared their frustrations with AI compromising academic work, art and creativity.“Art is a translation of human experience,” one participant said. “When people use AI, they diminish their own human experience.”Dr. Grant urged them, as “the last generation to remember a world before AI,” to remember the power of imagination and creativity – and to act on it.Remember that social media distorts perceptions: Stuart B. Murray, PhD, PsyD, who directs the Eating Disorders Program and Translational Research in Eating Disorders Program at UCLA, asked the students in his breakout session to take a spontaneous selfie and edit it to conform with society’s beauty standards. All 20 girls in the room immediately got to work, thickening their hair, slimming their faces, plumping their lips.“The pressure to look like what we present on social media can be crippling,” Dr. Murray said. “We now know that social media use is part of a causal pathway into an eating disorder.”Adolescents and young adults are most at risk of developing an eating disorder, he said, with one in three students on college campuses exhibiting clinically meaningful eating-disorder symptoms. More than 4 million people in California will have an eating disorder in their lifetime.Even for those who don’t develop anorexia or bulimia, the ubiquity of modified images online distorts what we consider normal, making us feel worse about ourselves. Remembering that, he and other speakers said, might inspire us to log off occasionally and spend time in the real world with people who love us as we are.
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Global webinar on core public health capacities to conduct ship inspections and issue ship sanitation certificates
Ships cross borders every day, connecting countries and serving as a backbone of the global economy. However, outbreaks onboard can disrupt maritime traffic, leading to significant economic and operational negative consequences. Without strong public health capacities to detect, prevent, and respond to public health risks on board ships, maritime travel can also become a pathway for the spread of infectious diseases. To support countries in strengthening these capacities, the World Health Organization (WHO) convened a two-day webinar on 11–12 February, bringing together more than 700 ship inspectors, port health officers, and public health authorities, primarily from the African, Eastern Mediterranean, and European Regions. The webinar came at a pivotal time. With the amended International Health Regulations entering into force on 19 September 2025, the need to focus on public health preparedness has never been greater. Strengthening public health capacities at borders, including onboard conveyances, is a cornerstone of global health security and central to the amended IHR.“The high level of attendance and active participation throughout the two days of the webinar highlighted the growing demand for technical guidance and capacity-building support in ship inspection and issuance of ship sanitation certificates”, said Dr Ninglan Wang, Head of the Borders, Mass Gatherings and Health Protection Measures (BMM) Unit at the Health Emergency Preparedness Department at WHO headquarters. “The dynamic interactions among experts and countries underscored the value of continued cross-border collaboration in the maritime sector and knowledge exchange in this area”. Conducting regular public health inspections on board ships for the issuance of ship sanitation certificates (SSCs) in accordance with the IHR requirements is crucial for ensuring that ships meet specific health standards, thereby minimizing the risk of the international spread of diseases via maritime traffic. These certificates, mandated by the IHR, require ports to have trained personnel who can identify and control public health risks on board vessels and apply recommended control measures. This standardized global procedure not only ensures compliance with the IHR but also promotes consistency in health practices across ports worldwide. SSCs are the globally-recognized tool used to prevent and control known public health risks on ships, providing a common way to register and communicate public health events and measures taken on board between all stakeholders involved in this process, including public health authorities in ports and ship operators. Only SSCs issued by ports authorized by national authorities to issue such certificates are considered valid. As per the IHR, all States Parties are required to send to WHO their list of authorized ports (available here) and to keep it updated. However, many Member States continue to face practical challenges, such as limited resources, high staff turnover, and competing priorities. These realities underscore the value of platforms such as this webinar, which foster collective learning, peer-to-peer exchange, and practical solutions to help countries build and sustain the capacities required under the IHR.Over the two days, participants engaged in presentations and discussions covering a wide range of technical and operational topics, such as the overarching international legal framework governing ship sanitation; considerations for pre-inspection planning; risk assessment factors by type of vessel; the completion and issuance of SSCs and evidence report forms; or practical insights on the inspection of various technical areas, such as food safety, medical facilities, water systems, or vector control, among others. In addition, public health authorities from the Netherlands, Morocco, and Tanzania shared case studies to showcase their practical application of these IHR requirements in their respective countries. Given its success, WHO plans to replicate similar sessions in the future to reach additional time zones and regions and cover other pressing border health-related topics, ensuring that Member States can continue benefiting from these opportunities to share knowledge and expertise.
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United States and Madagascar to Implement $175 Million Five-Year Health MOU - U.S. Embassy in Madagascar
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2025 US ACT on Health Equity Community Investments Recipients
Author: Kennesha VanBurch, Director, Health Equity and Community Investment Partnerships 2025 marks the fifth year of the US Accelerate Change Together (ACT) on Health Equity: Community Solutions Challenge (CSC) and National Strategic Collaborations (NSC). This year, we received more than 250 applications from organizations across the country dedicated to prioritizing the social, cultural and linguistic needs of communities that have experienced barriers to care and opportunity. The overwhelming response underscores the vital role these organizations play in advancing health equity at the local level and across the nation. Since the launch of ACT on Health Equity in 2021, the initiative has invested more than $18 million in nonprofit organizations and their health equity programming through CSC and NSC. This year, $3.4 million in funding has been provided to 47 nonprofit organizations that focus on healthcare access, nutrition and lung health. Together, we are making meaningful progress toward health equity across the US. Supporting Organizations Advancing Community Well-being and Health Equity The awarded organizations address critical needs across health, education, and social support through initiatives aligned with AstraZeneca’s areas of expertise, including lung disease, lung and breast cancer, and cardiology. Their work spans across culturally competent senior care, equitable healthcare access, cancer and chronic disease support, and preventive health education, as well as hunger relief, community gardening, dental and transportation services, and resources for underserved families. Together, they are working to remove barriers to care, reduce preventable conditions, and empower individuals and communities of all ages and backgrounds to achieve better health outcomes. Photo courtesy of Medical Motor Service of Rochester and Monroe County, Inc. Description: MMS driver speaking to a Wegmans shopper. GGWNY staff; Lincoln Memorial Church Community Garden and lead gardener Diane Learn more about our recipients and the impact they make within their communities below. Community Solutions Challenge Advocates for Women’s Health, Inc. Advocates for Women's Health exists to provide access to high quality prenatal care and gynecology care to lower-income communities in and around Fresno, CA. They operate a nonprofit OB/GYN clinic located in Fresno. American Rescue Workers (ARW) ARW is a faith-based, non-profit organization providing homelessness and hunger prevention services in Central PA since 1934. ARW cares holistically for men, women, and children who find themselves facing food insecurity, and emergency situations that may lead to homelessness, or an actual homeless crisis, by providing shelter and social services. ARW serves people no matter their faith, regardless of faith. Asian Americans Advancing Justice Southern California (AJSOCAL) AJSOCAL is a social justice organization that protects and strengthens the rights and dignity of AAPI communities, especially those that are most disadvantaged. Byrd Cancer Education and Advocacy (BCEA) BCEA’s mission is to effectively assist individuals battling cancer by connecting them to vital support and resources. BCEA ensures that all relevant information reaches those in need, guiding them towards the resources necessary to fight their battle against cancer. Catholic Charities of the Diocese of Santa Rosa Catholic Charities of the Diocese of Santa Rosa creates access to opportunities for self-sufficiency by providing innovative and compassionate services to people of all backgrounds, beliefs and cultures. Chosen Hearts Chosen Hearts’ mission is to rebuild lives and restore hope by fostering a sense of community and creating lasting, positive change. Columbia Student Medical Outreach The Columbia Student Medical Outreach Program (CoSMO) Clinic is the oldest and largest student-run free clinic at the Vagelos College of Physicians and Surgeons at Columbia University. At its core, CoSMO is guided by the belief that all people—regardless of immigration or insurance status—deserve access to high-quality, equitable medical care. Eagle’s Nest Community Kitchen and Resource Center and Mobile Pantry Eagle’s Nest Community Kitchen, Resource Center and Mobile Pantry’s mission is to empower underserved and rural communities through hands-on STEM education grounded in sustainable agriculture. By combining mobile workshops, community gardens, and mentorship, they deliver accessible training in science, technology, engineering, and math that builds practical skills, advances food security, and fosters environmental stewardship. Through collaborative partnerships and by honoring local knowledge, they cultivate resilient communities and inspire the next generation of agricultural innovators. eClose Institute eClose Institute’s mission is to make medically relevant scientific discoveries using an education platform that embraces equality and empowers participants to contribute ideas, life experience and experimental data to improve disease treatment. Equal Hope Equal Hope is an organization dedicated to saving lives and improving quality of life by eliminating health inequities. This organization challenges the status quo in striving to understand the context of people’s lives and the barriers they experience to help them achieve better health outcomes for their lives. Through research, quality assessment and improvements, advocacy, education, and patient navigation, they approach health holistically to achieve sustainable outcomes and true health equity. Food For Free Committee Food For Free improves access to healthy food through establishing innovative programming and partnerships to overcome barriers and strengthen the community food system. They believe that access to healthy food is a fundamental right. Grassroots Gardens of Western New York (GGRWNY) The missions of GGRWNY is to share knowledge, powers, and resources to grow health food, heal systemic harm, and strengthen neighborhood connections through community gardens. Greater Providence YMCA (GPYMCA) GPYMCA builds healthy spirit, mind, and body for all, through inclusive programs and relationships grounded in core values of caring, honesty, respect, and responsibility. Programs are intentionally designed to close equity gaps in health, education, and wellness. GPYMCA serves individuals and families across all life stages and income levels, including medically vulnerable and underserved populations. Hearts of Valor INC Hearts of Valor’s missions it to keep the heart pumping through advocacy, collaboration, education, and support. Ibn Sina Foundation Ibn Sina Foundation ensures the health of the community by providing integrated, preventive, and primary care in a clinical setting through the dissemination and application of health-related knowledge, thereby enhancing the quality of life for future generations. India Home India Home is a non-profit organization dedicated to addressing the needs of and empowering the South Asian and Indo-Caribbean senior immigrant community in New York City through culturally competent services. At India Home’s centers, seniors find community and resources through a diverse range of programs and activities. Programs include congregate meals, creative aging programs, case management programs, and educational talks on health, nutrition, financial safeguards and elder law. La Colaborativa La Colaborativa empowers the Latinx community, enhancing social and economic health, and holding institutional decision-makers accountable. Lancaster County Food Hub At the heart of the Lancaster County Food Hub’s (LCFH) work is a strong commitment to meeting basic human needs, fostering respectful relationships, and connecting neighbors with supportive services in a nurturing and welcoming environment. Guided by their vision of a Lancaster County where every individual is supported and empowered to live with dignity and stability, they strive to not only provide immediate relief but also to create pathways to lasting self-sufficiency. Maryland Foundation of Dentistry (MFD) MFD is dedicated to improving oral health outcomes and preserving dental function for one of the state’s most vulnerable populations: adults with intellectual, physical, and/or developmental disabilities who are unable to afford the cost of dental care. Maternity Care Coalition (MCC) The missions of MCC is to improve the health and well-being of pregnant women and parenting families and enhance school readiness for children 0-3. MCC achieves this through direct service, advocacy, and research, in collaboration with individuals, families, providers, and communities. Medical Motor Service of Rochester and Monroe County, Inc. Medical Motor Service of Rochester and Monroe County’s mission is to provide specialized transportation for community organizations, as well as individuals with disabilities and special needs to improve their independence and quality of life. Milwaukee Consortium for Hmong Health (MCHH) MCHH’s mission is to create a thriving and healthy Southeast Asian and Hispanic community by empowering families through education and screenings. MCHH utilizes established community health workers and focuses on addressing health disparities related to cancer and chronic disease among the Hmong, Bumese, Karen, Karenni, Lao, and Hispanic populations living in Milwaukee, WI and other areas if needed. Mission Hospice and Home Care Mission Hospice and Home Care is delivering compassionate support and exceptional care in the home for individuals and communities, guiding them with choice and dignity to navigate significant care decisions. North Alabama AHEC (NAAHEC) The mission of the NAAHEC is to improve healthcare access, quality, and equity in rural and underserved communities across North Alabama. They strengthen the health workforce - particularly through the development of community health workers by providing comprehensive training, resources, and advocacy. By fostering strong community partnerships and promoting healthcare literacy, NAAHEC aims to address disparities, improve outcomes, and cultivate a healthier future for North Alabama. Our Neighbors’ Table Hunger comes in many forms. Our Neighbors’ Table is committed to establishing a community that provides for the whole person with nourishing food, kindness and dignity. Panhandle Breast Health Panhandle Breast Health works to decrease breast cancer deaths by providing education and reducing financial barriers to increase screening rates. Pitney Meadows Community Farm Founded in 2026, Pitney Meadows Community Farm’s mission is to celebrate and explore agricultural education, healthy food production, and recreation. Located on 166 acres in the heart of the city of Saratoga Springs and preserved in perpetuity as a working farm, Pitney Meadows is a unique resource. Prince William County Community Foundation (PWCCF) PWCCF’s mission is to create a stronger, healthier, and more connected community by addressing critical needs in food insecurity, health & wellness, scholarship, and philanthropy. PWCCF is committed to empowering individuals and families through equitable access to nutritious food, comprehensive healthcare, educational opportunities, and community-driven support. By fostering partnerships and promoting sustainable solutions, PWCCF aims to enhance the quality of life for all, ensuring a brighter future for every member of their community. Raytown Christian Church (Raytown Summer Lunch Ministry) Raytown Summer Lunch Ministry’s mission is to provide nutritious and kid-friendly meals to children during the summer months when they are not in school and receiving school meals. Regents of the University of California, Davis UC Davis Health is improving lives and transforming health care by providing excellent patient care, conducting groundbreaking research, fostering innovative, interprofessional education, and creating dynamic, productive partnerships with the community. RSVP Volunteers RSVP Volunteers creates and runs unique community programs powered by skilled volunteers to advance education and wellness for all ages and strengthen nonprofits through capacity-building and volunteer services. Second Harvest Food Bank of Orange County Second Harvest Food Bank of Orange County, in collaboration with partners, provides dignified, equitable and consistent access to nutritious food, creating a foundation for community health. The Icla da Silva Foundation The mission of the Icla da Silva Foundation is to save the lives of patients whose only cure is a bone marrow transplant by providing financial, emotional, and logistical support to remove barriers to treatment. There With Care of the Bay Area Founded in 2012, the mission of There With Care of the Bay Area is to provide a wide range of meaningful and fundamental services to children and families during the critical phase of a medical crisis. Universal Community Health Center Universal Community Health Center’s mission is to provide quality and accessible healthcare to under-served communities and to provide a patient centered model of care to empower communities towards wellness. West Cancer Foundation West Cancer Foundation breaks through barriers to cancer care and improves patient outcomes by providing accessible patient resources, early detection and education, and community-based research. Westside Family Healthcare Westside Family Healthcare’s mission is to improve the health of communities by providing equal access to quality healthcare, regardless of ability to pay. National Strategic Collaborations Foundation of Asthma and Allergy Impact Rescue (AAIR) The mission of The Foundation for Asthma and Allergy Impact and Rescue (AAIR) is to make sure that every child is rescued at school, healthy at home, and connected to care. Family Reach Foundation Family Reach is a nonprofit that provides non-medical financial support to families facing cancer. Cancer treatment requires more than medicine — families need a roof over their heads and food on their tables to survive. If a family can’t meet these basic needs, cancer treatment takes a back seat. They work with patients, providers, and community organizations to challenge the systems that force families to choose between their health and their home. LUNGevity Foundation LUNGevity Foundation is transforming what it means to be diagnosed and live with lung cancer through research, advocacy, and community. This mission brings them closer to their vision: a world where no one dies of lung cancer. Association of Black Cardiologists The Association of Black Cardiologists is dedicated to preventing and treating cardiovascular disease, including stroke, through education, research, advocacy, and community engagement, striving for optimal health for all by eliminating disparities. Cholangiocarcinoma Foundation (CCF) The Cholangiocarcinoma Foundation’s (CCF) mission is to find a cure and improve the quality of life for those affected by cholangiocarcinoma (bile duct cancer). Founded in 2006, in Salt Lake City, UT, by a family who lost a loved one to cholangiocarcinoma, CCF has grown to become the leading global resource in research, education, and public awareness. ZERO Prostate Cancer Zero Prostate Cancer’s mission is to improve and save lives from prostate cancer through advocacy, awareness, education, and support. GO2 for Lung Cancer GO2 for Lung Cancer relentlessly confronts lung cancer on every front, every day, for everyone. As the nation’s leading lung cancer advocacy organization that was founded by patients and survivors, they are dedicated to increasing survival and quality of life for those at risk, diagnosed, and living with lung cancer. National Minority Quality Forum The National Minority Quality Forum (NMQF) is a national 501(c)(3) with a mission to reduce patient risk for all. Young Survival Coalition (Breast) Young Survival Coalition supports the young breast cancer community and ignites global collaboration to improve quality of life worldwide. Black Women’s Health Imperative Black Women’s Health Imperative’s mission is to solve the most critical health issues that Black women and girls face through innovative programs, transformative research, and lifesaving policies.
Seahawks Defense Still Feels Disrespected After Dominant Super Bowl Victory
Even after one of the most dominant defensive performances in Super Bowl history, the Seahawks still have a chip on their shoulder.
Game thread: Maryland men’s basketball at Minnesota
Maryland men’s basketball is in Minneapolis taking on Minnesota, looking to avoid a five-game losing streak — or at least for a competitive game. Tip-off at 2 p.m. Tip-off is set for 8:30 p.m. This is your space for thoughts, observations or whatever you would like to share, but please be respectful.
Experts Warn: The Dangerous Blur Between Science and Wellness in Mental Health Bestsellers
A marketplace where labels blur In many bookstores, titles rooted in clinical science sit inches from glossy self-help guides promising instant serenity. That proximity can make rigorous research look interchangeable with lifestyle advice, especially when everything shares the same bright displays. Readers encounter a single aisle labeled “psychology,” even when the content ranges from peer-reviewed evidence to spiritual rituals. The result is a subtle but pervasive blur, turning a complex health landscape into a grab-bag of mixed claims. Why the shelves can mislead Retail categories are built for convenience, not for methodological clarity or clinical accuracy. When “development personal” or “wellness” becomes the default bin, evidence-based psychology competes with coaching manifestos and mystical manuals. The visual language of covers—calming color palettes, confident subtitles, glowing endorsements—flattens the distinction between randomized trials and anecdotal wisdom. In that aesthetic harmony, a guide on cognitive behavioral therapy may appear no more “serious” than a book on moon manifestation. The stakes for readers and patients Confusion carries real risks, including delayed care when people self-treat serious symptoms with untested routines. Vulnerable readers—facing depression, trauma, or anxiety—may be swayed by charismatic voices over careful data. Some messages frame recovery as pure willpower, which can amplify shame when symptoms persist despite effort. Others overpromise universal solutions, ignoring cultural context, diagnostic nuance, and comorbidity. “Shelving is not neutral; it shapes beliefs, expectations, and choices.” What professionals and retailers are asking Clinicians and public-health experts argue for clear, readable signage that separates science-based mental health from broader wellness. Books by licensed psychiatrists or psychologists that cite peer-reviewed studies could be grouped under “Evidence-Based Mental Health.” Adjacent space might host reflective memoirs, coaching workbooks, or contemplative philosophy—valuable in their way, but clearly labeled as non-clinical guidance. Booksellers emphasize their dual role as cultural curators and commercial actors, noting they respond to demand while striving for quality standards. How clarity could look and feel The goal is not to police ideas, but to help readers navigate with confidence. Transparent categorization respects reader autonomy while lifting the signal of credible practice. Clear tags—such as “scientific references,” “clinical overview,” or “personal narrative”—can work like map legends, turning a maze into a route. And when a book blends modes, hybrid labels can acknowledge both insight and limitation. A practical checklist for choosing wisely Check the author’s credentials: clinical license, academic affiliation, or relevant training. Scan the references: citations to peer-reviewed journals or reputable guidelines. Look for scope limits: clear statements about who the book is and isn’t for, and when to seek care. Seek methods, not miracles: approaches tested across diverse groups, with measurable outcomes. Watch the language: be wary of absolute claims, stigmatizing tones, or one-size-fits-all promises. Cross-verify with trusted bodies: national psychology associations or public-health agencies. The publisher’s responsibility Publishers can raise the bar by standardizing disclosure on methods, sample sizes, and limitations. Editorial policies could require conflict-of-interest statements, transparent citations, and plain-language summaries of evidence. Marketing should avoid medicalized framing for books that lack clinical validation, even when sales incentives press for bold claims. When a manuscript mixes reflection with research, honest jacket copy can prevent false equivalence. Coexisting without confusion Wellness writing can offer genuine comfort, perspective, and daily habits that support well-being. Scientific texts can provide structured tools, validated therapies, and realistic expectations for progress. The aim is to let these strands coexist, while giving readers the navigational cues to tell them apart. With clearer shelves, informed labels, and modest design tweaks, we can protect reader trust—and keep the aisle both inviting and intelligent.
‘Mental health issues’: Tyson Fury responds to Deontay Wilder’s accusations of cheating
Tyson Fury says he’ll be taking the high road with respects to Deontay Wilder.
It’s Time to Pay Our Last Respects to The Washington Post
Democracy, the Post says, dies in darkness. Nowadays, newspapers are murdered in broad daylight.
Louisville business owner facing backlash after employee memo posted online
The owner told employees to "leave religion and politics at the door" after a police officer complained of disrespectful treatment, sparking criticism.
Former Michigan governors to lead forum on civility in politics
Four former Michigan governors will headline a bipartisan forum on civil and respectful discourse in politics Wednesday.
Lee Hamilton, towering figure in national politics with deep ties to IU, dies at 94
Lee Hamilton, a 17-term congressman serving southern Indiana, whose foreign policy expertise, reverence for democracy, and bipartisan ideals made him a towering and highly respected figure in national politics, died Wednesday. He was 94.
Key business publications spotlight new Sportservice leaders
Two recently appointed leaders of Delaware North’s Sportservice business – Tom Barney and Adrian Dishington – were profiled this month in Sports Business Journal (SBJ) and Buffalo Business First, respectively. Together, their stories highlight both the company’s deep bench of homegrown talent and its ability to attract global hospitality expertise to Buffalo. Tom Barney featured in Sports Business Journal In an interview […]
In Memoriam: Dr. Edgar J. McCullough, Jr.
In memory of Dr. Edgar J. McCullough, Jr., a distinguished scholar and educator, the college’s first dean, and a deeply respected humanitarian whose life’s work touched countless students, colleagues and communities.
Sunday Standings: Time to believe?
Over the summer, a respected voice like Elliotte Friedman really drove home a lot of feelings about the Pittsburgh Penguins in a podcast: “It’s really hard to make deals right now because there are 31 teams in the NHL attempting to get better….then there is Pittsburgh” Turns out the signings of players like Anthony Mantha, […]
Basil Talbott Jr., Chicago Sun-Times political editor and journalist, dies at 89
Basil Talbott spent more than 30 years at the Sun-Times and was widely respected by his colleagues as a truth-seeker who bluntly challenged obfuscation.
Oklahoma State, Utah look inward for more respectable defense
Both Oklahoma State and Utah have had a full week to consider what they need to improve to save their seasons.
Sydney Sweeney REJECTS calls to speak on politics
Actress Sydney Sweeney told 'Variety' politics are 'not an area I have ever imagined getting into' while calling for 'respect and understanding.'
A 65km hike into Norway's vanishing rural past
The Stølstruta offers hikers a responsible, respectful way to witness a pastoral tradition that has disappeared almost everywhere else in Europe.
Josh Allen Disrespects Patriots In New Sore Loser Comments
It’s always unlikable when a pro athlete plays the “shoulda, woulda, coulda” game during interviews, and that’s what Buffalo Bills QB Josh Allen just did. In a new presser, Allen insinuated that if he’d made one more play against the Denver Broncos in the Divisional round, the Bills would be headed to the Super Bowl […]
Online Graduate Business Programs Rank Among the Nation’s Elite
Five programs in the Naveen Jindal School of Management earned top-10 spots in their respective categories in the U.S. News & World Report 2026 Best Online Program rankings. The Naveen Jindal School of Management at The University of Texas at Dallas strengthened its reputation as one of the nation’s leading schools for online graduate business […]
The Republic of Korea–WHO country cooperation strategy 2026–2030
The Republic of Korea–WHO Country Cooperation Strategy 2026–2030 encapsulates our collective commitment to advance health and well-being for all. Rooted in mutual respect and collaboration, this country cooperation strategy (CCS) aligns with the shared regional vision of Weaving Health for Families, Communities and Societies in the Western Pacific Region (2025−2029), emphasizing the interconnectedness of our efforts.
iPhone 5s Gets New Software Update 13 Years After Launch
Alongside iOS 26.2.1, Apple today released an updated version of iOS 12 for devices that are still running that operating system update, eight years after the software was first released. iOS 12.5.8 is available for the iPhone 5s and the iPhone 6, meaning Apple is continuing to support these devices for 13 and 12 years after launch, respectively. The iPhone 5s came out in September 2013, while the iPhone 6 launched in September 2014.
Controversial Border Patrol chief and some agents expected to leave Minneapolis on Tuesday, sources say
Top Border Patrol official Gregory Bovino and some of his agents are expected to leave Minneapolis on Tuesday and return to their respective sectors, according to three sources familiar the discussions, sidelining a key player in the Trump administration’s immigration crackdown.
DrDisrespect Lies About Being Invited To Highguard Preview Event
The controversial streamer shared a post online claiming he was invited to a creator event for the new FPS
Drew Piers named President of Sachs Media as firm celebrates 30 years
'Drew is a motivating leader and a battle-tested strategist who is trusted by clients and deeply respected by our team.'
Is Caesars Entertainment (CZR) Pricing Reflect Its Value After Prolonged Share Price Weakness
If you are wondering whether Caesars Entertainment's share price reflects its underlying value or potential, this article walks through what the current valuation really suggests. The stock closed at US$23.61, with returns of a 6.9% decline over 7 days, a 3.4% decline over 30 days, roughly flat at 0.2% year to date, plus a 30.9% decline over 1 year and 55.1% and 68.0% declines over 3 and 5 years respectively, which can change how investors view both risk and opportunity. Recent news around...
Brother Martin’s 2-sport difference-maker is drawing the respect of opposing coaches
The Crusaders standout is also drawing interest from colleges in multiple sports. Here’s his story.
Naomi Osaka apologizes to Sorana Cîrstea for comments following tense handshake after win: 'I don't like disrespecting people'
Naomi Osaka and Sorana Cîrstea exchanged words after Thursday's match.
Naomi Osaka apologizes to Sorana Cîrstea for tense handshake after win: 'I don't like disrespecting people'
Naomi Osaka and Sorana Cîrstea exchanged words after Thursday's match.
Intel set to launch Arc Pro B70 with BMG-G31 GPU
BMG-G31 finally launching 'soon' Finally, Intel is set to launch its BMG-G31 graphics card, but it is not for gamers, it seems. Respected Intel hardware
SM Entertainment targets M&A deals and AI tech integration as K-pop giant outlines ‘NEXT 3.0’ strategy
The K-pop powerhouse is also aiming to build Asia’s “largest and most respected publishing company” via its Kreation Music Rights (KMR) subsidiary…
Latest iPhone 18 Pro Leak Corroborated by Respected Former Analyst
Respected veteran display analyst Ross Young has added his support to a new leak today about the iPhone 18 Pro's front-panel design. In a new post on X (Twitter), the now-retired Counterpoint Research VP said that Chinese leaker Instant Digital's latest explanation of how Apple will shrink the Dynamic Island is what he was alluding to in a report last year.
Teens Are Asking to Be Seen: The Politics of Growing Up
Teens are stepping into political and moral awareness. They seek validation and want respect and recognition, not dismissal, as they shape the future they’ll inherit.
Trump urges Louisiana Rep. Julia Letlow to run for U.S. Senate: ‘Run, Julia, Run!”
Trump referred to Letlow as a “Highly Respected America First Congresswoman” and said she is “Great Star, has been from the very beginning, and only gets better!”