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Glyphosate: A story of science, risk, and nuance
In the summer of 2014, a California groundskeeper named Dewayne Johnson started noticing patches of raw, weeping skin spreading across his body. He had spent years applying Roundup, Monsanto’s glyphosate-based herbicide, for a school district, sometimes drenched in it when equipment malfunctioned. By 2014, he had a diagnosis: non-Hodgkin’s lymphoma. In 2018, a jury awarded him $289 million in damages, later reduced on appeal. Tens of thousands of lawsuits followed. The story hasn’t quieted down. It’s all over the internet, swinging between “this will kill you, buy organic” and “relax, you’re fear-mongering.” Some of that recent chatter stems from an Executive Order protecting glyphosate and its production, which set off intense infighting within the MAHA movement. Some of it reflects a deeper truth: Americans genuinely care about harmful chemicals in their environment (see poll below). And the conversation isn’t going anywhere, with a Supreme Court case involving Monsanto set for this April. Glyphosate (the active ingredient in Roundup) is one of the most widely used herbicides in the world. But does glyphosate cause cancer? And how much exposure is actually risky? With so much mistrust in institutions and corporations (and some genuine conflicts of interest), making sense of the actual scientific evidence is genuinely hard. Here is a translation of what the scientific evidence actually says. Does glyphosate cause harm? Glyphosate is an herbicide that kills most plants it contacts rather than targeting specific species. It works by blocking an enzyme pathway (EPSPS) that plants and many microorganisms need to produce essential amino acids. Without those amino acids, the plant can’t grow and dies. Glyphosate was first developed by Monsanto in the 1970s and became ubiquitous after the company introduced “Roundup Ready” crops in the 1990s. In 2024, Bayer removed glyphosate from residential Roundup-branded products due to litigation pressure. But today it is still the most widely used herbicide in the world. Farmers also discovered they could spray it directly on crops like oats, lentils, beans, and peas just before harvest to dry them out faster and make harvesting easier. Because of its widespread use, it’s obviously really important to understand if it’s harmful to humans. The key principle: The dose makes the poison The most important concept in toxicology is that “the dose makes the poison.” Sixteenth-century physician Paracelsus articulated what remains the foundational principle of toxicology: sola dosis facit venenum. Water will kill you if you drink enough of it. Aspirin saves lives at 81 milligrams and causes internal bleeding at higher chronic doses. So, at what dose is glyphosate poisonous? The LD50 in rats (the dose that kills half the test animals) is around 5,600 mg/kg body weight. Table salt is roughly 3,000 mg/kg. By that classic measure, glyphosate is less acutely toxic than salt. But some people are exposed to a lot of glyphosate through their work. And among the general public, there are many questions about low-dose, cumulative exposure from multiple sources over long periods. Does glyphosate cause health problems? Cancer Correlation maps are striking, with one analysis finding that 60% of counties that spray the most glyphosate have non-Hodgkin’s lymphoma rates above the national average. But correlation alone doesn’t establish cause, which is why animal and human studies matter. In animals: Rat studies are typically what most fear is rooted in, but most people don’t know the study details on the dosage given to rats. A pooled analysis of the 13 most rigorous rat studies found evidence that very high doses, around 55,000 times greater than typical food residue exposure, can cause certain cancers. In humans: One of the strongest studies followed 55,000 herbicide users over 20 years and found no overall increased cancer risk. There was one signal: among those with the highest use, rates of acute myeloid leukemia (AML) appeared elevated. A broader meta-analysis of 18 human studies also found no overall cancer risk, though a separate meta-analysis focused specifically on non-Hodgkin lymphoma found that people with high cumulative glyphosate exposure faced a 41% higher relative risk compared to those with low or no exposure. These human studies are observational studies (randomized controlled trials would be unethical), and meta-analyses are only as reliable as the studies they pool. But the story seems consistent: at very high exposure levels, there may be some cancer risk. But that’s about as far as the science currently takes us. Emerging research: gut and reproductive health Gut: Because glyphosate targets a pathway that exists in some gut bacteria, scientists have questioned whether it could affect the microbiome. In mice, a 2023 University of Iowa study found that glyphosate altered gut bacterial composition and raised markers of intestinal inflammation. A 2024 systematic review found similar patterns: disrupted gut bacteria and problems with the mucus layer that protects the intestinal wall in mice. Whether this translates to humans is an open question. The human gut is highly variable and resistant, and we don't yet have strong studies confirming the same effects in people. Reproductive health: Animal studies have found that glyphosate-based herbicides can interfere with reproductive hormones, including disrupting egg cell development in mice and reducing the number of eggs available in sheep’s ovaries. However, the doses used in these experiments were high, so it’s not yet clear whether the same effects would occur in humans. On the human side, a 2021 pilot study led by Mount Sinai researchers tested urine samples from pregnant women across the U.S. and found glyphosate in 95% of them. The study also found a possible connection between higher glyphosate exposure during pregnancy and a subtle physical difference measured in female newborns. That said, some connections weren’t statistically reliable and this was a small study. The researchers themselves said more and larger studies are needed before drawing firm conclusions. What do regulators say about glyphosate safety? In 2015, the International Agency for Research on Cancer (IARC), part of the World Health Organization, classified glyphosate as "probably carcinogenic to humans" (Group 2A). The classification is worth taking seriously. But, there’s an important distinction: IARC classifies hazard, meaning the potential to cause harm under some conditions. It does not assess risk, which accounts for actual exposure levels and the real-world probability of harm. The U.S. EPA, the European Food Safety Authority, Health Canada, and regulatory agencies in Australia and Japan have all concluded that glyphosate is “unlikely to be carcinogenic to humans” at realistic exposure levels. They’re asking a different question: given how much of this people actually encounter, what is the probability of harm? Your actual exposure is what determines your actual risk. What does glyphosate mean for your daily life? At the grocery store: Food residues are small. The EPA’s acceptable daily intake is 1.75 mg/kg of body weight per day. To hit that threshold from oatmeal alone, a 150-pound adult would need to eat roughly 50 pounds of oats every day. But this calculation addresses only one pathway (food), and we don’t yet have robust tools to measure people’s actual total exposure. If reducing exposure matters to you, organic certification prohibits synthetic herbicides, and organic oat products generally test at lower or undetectable levels. Either way, a diet rich in whole grains, conventional or organic, is far better for your health than one that omits them out of fear of residues. On the farm: Occupational exposure is orders of magnitude higher than consumer exposure. Farmers and farm workers who mix, load, and apply glyphosate-based herbicides, especially without protective equipment, face meaningfully different risk profiles. Proper PPE isn’t optional. Integrated weed management strategies that rotate chemical modes of action are also worth taking seriously, both for health and for long-term effectiveness. If you live near a farm: Spray drift is real. Concentrations near field edges can spike during and after application, particularly on windy days. This is an area where I think public health could really step up and empower rural communities with buffer zones, rather than placing the onus on individuals. But for now, knowing your local agricultural calendar and keeping windows closed during application are the first steps. Bottom line Dewayne Johnson was exposed to glyphosate at levels most people will never encounter, and a jury decided he deserved compensation. That outcome is not evidence that the oatmeal in your pantry is dangerous. But it is a reminder that the dose, the context, and the person doing the exposing all matter enormously. Glyphosate is a chemical tool with benefits, trade-offs, and genuine open scientific questions. Learning to hold that complexity without collapsing into panic or dismissal is, honestly, one of the most useful and hardest things to do in navigating modern health science. Love, YLE Your Local Epidemiologist (YLE) is founded and operated by Dr. Katelyn Jetelina, MPH PhD—an epidemiologist, wife, and mom of two little girls. Hannah Totte, MPH, is an epidemiologist and YLE Community Manager. YLE reaches more than 425,000 people in over 132 countries with one goal: “Translate” the ever-evolving public health science so that people will be well-equipped to make evidence-based decisions. This newsletter is free to everyone, thanks to the generous support of fellow YLE community members. To support the effort, subscribe or upgrade below: Subscribe
Marathon has sold 1.2M copies across Steam, PS5, and Xbox
Alinea Analytics estimates show that Marathon has generated gross revenues of $55M via 1.2M copies sold on Steam, PS5, and Xbox: Looking at the split between Steam, PS5, and Xbox, Steam is clearly the main platform for Marathon, accounting for a little under 70% of the audience (800K copies sold). Meanwhile, PS5 takes about 19% (217K) and Xbox (including console, PC, and cloud) accounts for a bit over 11% or 133K. Marathon is technically a first-party Sony title, so seeing the home console struggle to break 20% of the volume is a notable data point for the ongoing platform-agnostic debate. PlayStation Studios online games will almost certainly continue being multiplatform (despite Sony reportedly pulling back on PC releases). Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe As for Marathon, the consensus among hardcore players who pushed through the awkward onboarding phase – myself included – is that it’s fantastic. The gunplay, aesthetic, and presentation are among the best in the shooter genre. A great game doesn’t always equal an immediate hit, though, as shown by our estimates. Things are looking lukewarm right now. But this might be one of those marathon-not-a-sprint situations. Had to, didn’t I? Why wasn’t Marathon a hit on the same level as Arc Raiders? One topic that came up in a lot of conversations at GDC this year was why Marathon hasn’t hit the same stratosphere as Arc Raiders. On paper, they’re both extraction shooters, and Marathon has the Bungie pedigree – the house that built the gold standard for gunplay in Halo and Destiny. Marathon’s neon-futuristic aesthetic also distinguishes itself from the gritty realism of Tarkov or the post-apocalyptic hope of ARC Raiders. But vibes can only get you so far for first impressions if the onboarding feels like a brick wall. Marathon is a sweaty PvP-focused experience with a first-time user experience and UI that I can only describe as dreadful. Players are dropped into a complex ecosystem where the UI, though visually striking, is functionally uninformative, forcing users to manually hover over nondescript, identical icons just to identify basic gear or weapon mods. This lack of clarity is compounded by punishing mechanics like a severe heat gauge for movement and a scarcity of vital resources, all without a clear tutorial or a low-stakes mode to learn the ropes. Most people – even top streamers and veteran shooter players – have no idea what’s going on in Marathon at first. Arc is on the complete other end of the spectrum. As we covered here and here, Arc Raiders offers a more collaborative, approachable loop where players often work together toward shared goals. And the objectives are instantly clear. To many players, this contrast only emphasised Marathon’s issues, especially during the testing period. Players understand the Arc Raiders loop within 30 minutes, while Marathon acts as a massive filter, chewing up newcomers and spitting them out before they can experience the depth of Bungie’s signature gunplay. What I’m getting at here is that the poor first-time user experience of Marathon’s Server Slam likely stifled launch sales, while the opposite was true for Arc. Let’s look at the pre-launch copies sold for each game during their respective Server Slams (launch-aligned) : Looking at the trajectory: Arc Raiders saw a massive 80% jump in copies sold during its three-day Server Slam (day -13 to -11). Players jumped in, realised the water was fine, and immediately opened their wallets. Marathon, meanwhile, saw a 49% increase in the four days following its Slam (Day -7 to -3). At the time of each game’s respective launch, Arc Raiders had nearly double the Steam footprint of Marathon – and word of mouth only continued to grow. Bungie could have had more time to fix the onboarding process had the beta happened earlier. But Marathon launched three days after the beta finished. These factors limited the launch sales quite a bit, I reckon. Marathon has found a niche audience, though Despite the friction-heavy start, the data suggests that those who survived Marathon’s onboarding are loving life. We’ve been tracking cross-platform DAUs, and while there’s the expected post-launch leakage, many players are sticking with it. After peaking at 478K total DAUs on its first Saturday, Marathon has settled into a respectable rhythm, holding 345K DAUs as of yesterday and averaging 380K DAUs across the weekend. Steam continues to do the heavy lifting here, consistently accounting for the lion’s share of the daily players. Players have been putting in the hours, too: On Steam, Marathon’s average playtime has climbed to 27.8 hours, significantly outpacing the console averages on PS5 (16.5h) and Xbox (17.3h). Even more telling than the averages: 22% of the Steam audience has surged past the 50-hour mark, and nearly 7% have already logged over 100 hours. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe This data suggests that once the Bungie magic clicks, it hooks players deeper than the average extraction shooter. There’s also started to be a shift in the game’s discourse. Marathon launched as one of those games that’s cool to hate. But as Marathon’s 100-hour club grows, we’re seeing conversations around its mechanical merit outweigh the negativity. Several high-profile creators, who were initially vocal critics, have spent the last week coming around on the mechanical depth of the endgame. It’s a subtle but positive signal; the hate train is losing steam, and a new narrative about the game is emerging. Bungie faithfuls unite Another interesting metric in Marathon’s first few weeks is who, exactly, is playing. Bungie leans heavily on its prestige as the “makers of Halo and Destiny,” in its marketing, and that message has clearly hit the mark. On Steam, the gravity (hammer) of Bungie’s previous work is unavoidable. A staggering 78.2% of Marathon players also played Destiny 2. The trend carries across other platforms, with 74.2% of PS5 players and 82.7% of Xbox players also having played Destiny 2. The Halo legacy lives on, it seems. More on that in a bit. While Destiny 2 went free to play, these numbers still represent a high-intent migration of a fanbase that trusts Bungie’s specific brand of kinetic gunplay and cryptic world-building. The Xbox data adds another layer of legacy. About 85.7% of Marathon players on Xbox have played Halo Infinite, while over half of the Steam audience has spent time in Halo Infinite and 36.1% in the Master Chief Collection (a paid collection of the old Bungie-made legacy games). Interestingly, we see a 55.9% overlap with ARC Raiders on Steam. Overlap is even higher there on PlayStation (60.5%) and Xbox (66.5%). And there’s also significant crossover with Helldivers 2 on all platforms, too. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe Bungie has found some of its fans with Marathon, and the challenge now is keeping this engaged in a high-stakes PvP environment when they’ve spent the last decade primarily enjoying the power fantasies of PvE. On that note… Go the full 26 miles? Or cut and run? Time for some could’ve, should’ve, would’ve. These things would have improved Marathon’s performance at launch: A more robust onboarding process, perhaps in the form of a short single-player/PvE campaign. We know Bungie fans love this stuff. A traditional arena-based mode akin to Destiny’s Crucible could have been a bridge for the cautious players who’d have been otherwise deterred by the Server Slam. It’s also a great palate cleanser after getting merked. Introducing a dedicated PvE environment would have similarly diversified the conversation and lowered the barrier for the Bungie faithful who found the pure PvP extraction loop too abrasive. PvE is safer than PvP these days. There’s an argument that a thin PvE mode would have just felt like a budget Destiny, potentially hurting the brand more. But given how dire the FTUE is, I think it would have been a net positive. Any kind of tutorialised loop that demystifies the stakes, really. While there is merit in a studio sticking firmly to a singular creative vision, and going all in on the hardcore extraction loop. Less forgiving is the technical reality is that the user interface and first-time user experience (FTUE) were not at a commercial standard for launch. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe In a landscape where player time is oversaturated and the most contested currency, a flawed FTUE is a critical failure point. But it’s not all doom and gloom, as Marathon has an incredible, unique gameplay loop, suggesting that financial success is still attainable if Bungie can pivot effectively. Bungie and PlayStation now face a difficult strategic crossroads, though – one within a challenging games market. They could: Double down on Marathon with a long-term Rainbow Six Siege- or No Man’s Sky-style recovery plan, which is something I heard Last Stand Media’s Chris Maldonado mention last week. While this could be a sunk-cost fallacy in action, it could eventually yield the audience the game’s mechanical depth deserves. Shift focus toward the inevitable Destiny 3 or another project, mitigating the escalating opportunity cost and cutting their losses, so to speak. Doing both is an expensive proposition, given the high overhead and burn rate of operating out of Bellevue, Washington. With Sony recently demonstrating a lower threshold for underperforming studios and projects, the margin for error has vanished. Whatever happens, the next six months will determine whether Marathon becomes a cornerstone of Sony’s live-service portfolio or a cautionary tale of vision exceeding accessibility. I’m hoping it’s the former, because Marathon rocks. As always, hit subscribe to get updates on Marathon and other relevant games. Subscribe Want to get your hands on our data for yourself – for free? We’re offering a free trial of our platform for games companies. Send us a message here, or reply to this email, and we’ll set you up. The last word Reply to this email – or reach out here – if you have any feedback for the newsletter – or want to request a game for us to cover. [Alinea Analytics boasts the most accurate PC and console estimates in the business. Game makers use our platform to understand their audience, keep an eye on the competition, monitor sales trends, and spot new opportunities. We equip game studios and financial institutions with accurate data and the confidence to make smarter, data-driven decisions. Want to talk about all things games market data? We’d love to chat!]
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STORY: As global markets react to the U.S. Supreme Court ruling on President Trump's tariffs, Nvidia earnings head for center stage. These are the stories to watch in business and finance in the coming week. :: Nvidia's momentMarkets will be watching for Nvidia's quarterly results Wednesday...as investors worry about returns on AI spending and industry disruptions caused by the emerging tech.Nvidia shares have soared following the launch of ChatGPT in late 2022.But shares of the company and others in the "Magnificent Seven" have stalled so far in 2026.:: Anniversary angstTuesday marks the four-year anniversary of Russia's full-scale invasion of Ukraine.While the push for a ceasefire continues, getting one over the line remains difficult.Ukraine has faced sustained pressure to agree to a deal that could mean painful concessions, as Russian forces pound its power grid and slowly advance on the battlefield.The International Monetary Fund looks set to rubberstamp extended support, meaning Kyiv's bonds are flying high.:: Key Australia dataAustralia's consumer price reading Wednesday will be closely watched by investors, who are betting the central bank will hike rates at least once more this year.Earlier this month, Australia's central bank became the only one in the G10 outside Japan to tighten policy, as it struggles to bring inflation under control in a supply-constrained economy.:: British uneaseBritish Prime Minister Keir Starmer faces a reckoning Thursday in a Manchester special election.Investors will be watching the results closely. Friday could be another volatile day for British markets and Westminster.British gilts and the pound wobbled earlier this month as a crisis engulfed Starmer over what he knew of Peter Mandelson's links to late sex offender Jeffrey Epstein when he appointed the former as U.S. ambassador.
Live Nation Entertainment Full Year And Fourth Quarter 2025 Results
In 2025, the bond between artists and their global fan bases reached new heights, fueling another year of double-digit growth. As artists continue to unlock untapped markets and headline the world’s most iconic stadiums, we’ve built momentum that carries us into a record-breaking 2026. We’re not just building venues; we’re crafting world-class stages designed to elevate the artist’s vision and their connection to fans. By strategically expanding our global footprint and investing in premium, upgraded infrastructure, we provide the canvas for career-defining performances. This investment doesn’t just drive ticket sales—it revitalizes local economies and cements our venues as cultural anchors. With a deep pipeline of large-scale shows and ticket demand continuing its ascent, we are positioned for another year of double-digit operating income and AOI growth in 2026. Our commitment to being the ultimate partner for artists ensures we are set to compound this double-digit growth for years to come. – Michael Rapino, President and CEO
Healthy Returns: FDA chief Marty Makary on compounded GLP-1s, vaccines and China
Makary helms the FDA in the midst of a contentious stretch for the agency, defined by massive staff and budget cuts and sweeping changes to vaccine policy.
AI breakthrough could replace rare earth magnets in electric vehicles
Scientists at the University of New Hampshire have unleashed artificial intelligence to dramatically speed up the hunt for next-generation magnetic materials. By building a massive, searchable database of 67,573 magnetic compounds — including 25 newly recognized materials that stay magnetic even at high temperatures — the team is opening the door to cheaper, more sustainable technologies.
Obama’s Reminder About the Futility of Purity Politics
The late, great journalist Mark Shields often propounded the idea that politics should be about looking for converts rather than punishing heretics.
This Week in Science: Mars Molecules, a Cholesterol-Cutting Compound, And More!
Our weekly science news roundup.
Climate, Energy, & “Wrecking Ball Politics” | Council on Foreign Relations
This is a limited excerpt from the Climate Realism Initiative Newsletter. Sign up to receive monthly insights from the initiative’s fellows and staff, including articles, videos, podcasts, events, and more. Demolition Man Bankruptcy, wrote Ernest Hemingway, finds you two ways: “Gradually, then suddenly.” Small decisions, omissions, and mistakes compound over time, at first imperceptibly, then inescapably, until […]
Episode 18: Massive Attack helped me build a multi-million pound business
Join Jonathan Boyers, Head of Alvarez & Marsal Corporate Finance, and Chris Maguire, Executive Editor of BusinessCloud, as they sit down with Fernando Kufer, CEO of Emmy award-winning visual experiences giant Disguise.In this episode, Fernando Kufer discusses:How watching Massive Attack at Glastonbury in 2014 changed his life Speaking 7 different languagesTripling the size of DisguiseSurviving and then thriving after Covid
NASA scientists say meteorites can’t explain mysterious organic compounds on Mars
Scientists studying a rock sample collected by NASA’s Curiosity rover have uncovered something tantalizing: the largest organic molecules ever detected on Mars. The compounds — decane, undecane, and dodecane — may be fragments of fatty acids, which on Earth are most often linked to life. While non-living processes like meteorite impacts can also create such molecules, researchers found those sources couldn’t fully explain the amounts detected.
Women in Science: Climate Impact Researcher Sanketa Kadam
In honor of International Day of Women and Girls in Science, we’re featuring Kadam, who researches compound extreme events in India and their impacts on crops and farmland.
Just look at Ayaneo's absolute unit of a Windows gaming "handheld"
The Ayaneo Next II pushes past 3 pounds, 1 inches wide, and costs up to $4,300.
Seahawks ride their 'Dark Side' defense to a Super Bowl title, pounding the Patriots 29-13
SANTA CLARA, Calif. (AP) Defense won this championship.
New drug resets the body clock and cuts jet lag recovery nearly in half
Scientists have identified a promising new compound, Mic-628, that can reliably shift the body’s internal clock forward—something that’s notoriously hard to do. By targeting a key clock-control protein, Mic-628 jump-starts the gene that sets daily rhythms, synchronizing both the brain’s master clock and clocks throughout the body. In mice experiencing simulated jet lag, a single dose cut recovery time nearly in half.
Hims & Hers responds to FDA pressure, pulls knockoff Wegovy drug launch after regulatory threats
Telehealth company Hims & Hers cancels $49 monthly weight loss drug launch following FDA warnings about unapproved semaglutide compounds and Novo threats.
Hims & Hers stops selling weight loss pill days after unveiling it
Hims & Hers said it would stop selling its new compounded semaglutide pill after "constructive conversations with stakeholders across the industry."
Hims & Hers will stop selling compounded version of Novo’s obesity pill
Hims & Hers will stop selling what it claims to be a cheaper, compounded version of Novo Nordisk's obesity pill on its telehealth platform.
Hims & Hers to stop offering compounded semaglutide pill after FDA crackdown
Hims & Hers said in a statement on Saturday that it will stop offering access to the compounded semaglutide pill after the U.S. Food and Drug Administration said it would take action against the telehealth provider for its $49 weight-loss pill.
Melissa Joan Hart dropped 20 pounds by cutting two things in her ‘longevity journey’
Melissa Joan Hart lost 18 pounds by cutting two things from her diet during her midlife wellness journey. The former "Sabrina the Teenage Witch" star reveals her approach.
That dry, bitter taste may be waking up your brain
New research suggests the astringent sensation caused by flavanols could act as a direct signal to the brain, triggering effects similar to a mild workout for the nervous system. In mouse experiments, flavanol intake boosted activity, curiosity, learning, and memory—despite these compounds barely entering the bloodstream. The key appears to be sensory stimulation: the taste itself activates brain pathways linked to attention, motivation, and stress response, lighting up regions involved in arousal and memory.
NASA Study: Non-biologic Processes Don’t Fully Explain Mars Organics
In a new study, researchers say that non-biological sources they considered could not fully account for the abundance of organic compounds in a sample
Fear among Minnesota’s Somali community compounds a public health woe: Low measles vaccination rates
Public health officials say a measles crisis has long been brewing in Minnesota.
Fear among Minnesota's Somali community compounds a public health woe: Low measles vaccination rates
Public health officials say a measles crisis has long been brewing in Minnesota
VIEW Hims and Hers Health's compounded Wegovy pill offering fuels market jitters
Hims & Hers said it would begin offering compounded versions of Novo Nordisk's Wegovy pill at an introductory price of $49 per month.
1,000 lbs of chicken wings. Local businesses prepare for Super Bowl rush
Restaurant owners are preparing for the Super Bowl, including one local owner who bought 1,000 pounds of chicken wings.
Quebec fisherman reels in 244-pound, record-breaking Atlantic halibut — for science
Alain Hamel caught the largest Atlantic halibut ever recorded in the Saguenay Fjord on Saturday. Working with the local Fjord Museum, the ice fishing was part of a scientific project aiming to gain more information about the species.
Can AI ‘vibe research’ replace social science?
AI tool improvement is compounding fast enough for researchers to start using tools like Claude Code for real social science tasks.
Downtown Springfield business moving to exclusively online sales
Clothing retailer 5 Pound Apparel announced it will close its downtown Springfield storefront by the end of February.
BKB 50 results, video highlights from ‘Evolution’ in Miami
BKB Bare Knuckle Boxing celebrated its 50th event last night (Sat., Jan. 31, 2026) with BKB: “Evolution” from inside James L. Knight Center in Miami, Florida. BKB 50 was headlined by the super featherweight title fight pitting undefeated 130-pound phenom Alberto “El Indio” Blas opposite five-fight BKB veteran Harold “Lightning” McQueen, widely-regarded as one of […]
Scientists discover how to turn gut bacteria into anti-aging factories
Researchers found that small doses of an antibiotic can coax gut bacteria into producing a life-extending compound. In worms, this led to longer lifespans, while mice showed healthier cholesterol and insulin changes. Because the drug stays in the gut, it avoids toxic side effects. The study points to a new way of promoting health by targeting microbes rather than the body itself.
Scientists may have been wrong about what causes asthma
Asthma may not be driven by the molecules scientists have blamed for decades. Researchers have identified “pseudo leukotrienes,” inflammation-triggering compounds formed by uncontrolled free-radical reactions rather than normal enzymes. These molecules were found at much higher levels in people with asthma, closely tracking how severe their symptoms were. The finding hints at a new way to treat asthma by preventing the inflammatory spark instead of blocking its aftermath.
550-pound Ice Age kangaroos could still hop
Just probably not as far as today’s marsupials.
Man Who Lost More Than 300 Pounds Reveals the 1 Lifestyle Change He's Keeping Up
After trying countless diets, Matthew Castillo didn't know what to do next. Then his friend had the solution.
World enters 'era of global water bankruptcy': UN scientists formally define new post-crisis reality for billions
Amid chronic groundwater depletion, water overallocation, land and soil degradation, deforestation, and pollution, all compounded by global heating, a UN report today declared the dawn of an era of global ...
How scientists are turning thyme into precision medicine
Thyme extract is packed with health-promoting compounds, but it is difficult to control and easy to waste. Researchers created a new technique that traps tiny amounts of the extract inside microscopic capsules, preventing evaporation and irritation. The method delivers consistent nanodoses and could eventually be used in medicines or food products. It may also work for many other natural extracts.
Health needs, insurance woes compound fears for Minnesota families amid ICE operations
Health care providers say the Twin Cities immigration enforcement surge is leading people to cancel doctor’s appointments and delay treatments even if they’re U.S. citizens or have other legal status in the country. Fears of losing health insurance are also mounting.
Ashton Kutcher says designer fired him for being 'too fat' in pink Speedo
Ashton Kutcher alleged that Tom Ford fired him from a Gucci modeling job for looking 'too fat' in a pink Speedo: 'I was 178 pounds, what are you talking about?'
Scientists “resurrect” ancient cannabis enzymes with medical promise
Scientists have uncovered how cannabis evolved the ability to make its most famous compounds—THC, CBD, and CBC—by recreating ancient enzymes that existed millions of years ago. These early enzymes were multitaskers, capable of producing several cannabinoids at once, before evolution fine-tuned them into today’s highly specialized forms. By “resurrecting” these long-lost enzymes in the lab, researchers showed how cannabis chemistry became more precise over time—and discovered something unexpected: the ancient versions are often more robust and easier to work with.
Scientists find a natural sunscreen hidden in hot springs bacteria
Researchers studying cyanobacteria from hot springs in Thailand have discovered a new natural UV-blocking compound with impressive antioxidant power. Unlike conventional sunscreens, it’s biocompatible and potentially safer for both people and the environment. The molecule is produced only under UV and salt stress and uses a unique biosynthetic pathway never seen before. This could help drive a new generation of eco-friendly sunscreens and skincare products.
At This Office Park, Scamming the World Was the Business
Times journalists got a rare look inside one of the compounds where the online fraud industry makes its billions. Inspirational slogans (“Keep going”) were just the start.
A new crystal makes magnetism twist in surprising ways
Florida State University scientists have engineered a new crystal that forces atomic magnets to swirl into complex, repeating patterns. The effect comes from mixing two nearly identical compounds whose mismatched structures create magnetic tension at the atomic level. These swirling “skyrmion-like” textures are prized for their low-energy behavior and stability. The discovery could help drive advances in data storage, energy-efficient electronics, and quantum computing.
Newly discovered coffee compounds beat diabetes drug in lab tests
Roasted coffee may do more than wake you up—it could help control blood sugar. Researchers discovered several new coffee compounds that inhibit α-glucosidase, a key enzyme linked to type 2 diabetes. Some of these molecules were even more potent than a common anti-diabetic drug. The study also introduced a faster, greener way to uncover health-boosting compounds in complex foods.
This Week in Science: Anti-Cancer Fungal Compound, a Golden Shark, And More!
Our weekly science news roundup.
Barton Health welcomes first baby of 2026
SOUTH LAKE TAHOE, Calif. – Barton Health welcomed the first baby of the New Year on January 6 at 2:36 p.m. Murphy Vera Ross, female, weighing 7 pounds, 11 ounces, and measuring 20 inches long, was born to Ashley Brier Ross and Barret Ross of South Lake Tahoe, CA. Dr. Megan Jewell, board-certified obstetrician and gynecologist...
Matt Damon says changing his diet got him to his 'high school' weight
"I did that whole movie at 167 pounds. And I haven't been that light since high school," Matt Damon said.
100-pound concrete pig medallion returns to Washington business
The stolen medallion and outdoor chairs showed up overnight at a nearby business.
Scientists find a safer way to make cells burn more calories
Researchers have developed experimental compounds that make cells burn more calories by subtly tweaking how mitochondria produce energy. Older versions of these chemicals were once used for weight loss—but were banned for being deadly. The new approach fine-tunes the effect, allowing cells to burn extra fuel safely. If successful, this could pave the way for new obesity treatments with added health benefits.
The invisible microbes that help keep us healthy
Not all microbes are villains—many are vital to keeping us healthy. Researchers have created a world-first database that tracks beneficial bacteria and natural compounds linked to immune strength, stress reduction, and resilience. The findings challenge the long-standing obsession with germs as threats and instead highlight the hidden health benefits of biodiversity. This shift could influence everything from urban design to environmental restoration.
Jelly Roll Opens Up About His 275-Pound Weight Loss Journey on Cover of ‘Men’s Health’
Jelly Roll opened up about his weight loss journey in a cover story for Men's Health.
Under Fire for Trump Rulings, Chief Justice Says Courts Still Check Political Power
John Roberts in year-end report expounds on judicial independence as the court faces criticism for being deferential to Trump.
Bachelorette Alum Ali Fedotowsky Says She's Putting Her "Health First" Ahead of Weight Loss Journey
Bachelorette alum Ali Fedotowsky shared that after gaining 10 pounds in the last two months, she was focusing on not just weight loss, but on her strength in an effort to get healthier.
Zelensky to meet Trump as Russia continues to pound Ukraine
Zelensky will visit Trump at Mar-a-Lago to discuss raising pressure on Russia, security guarantees and investment in postwar reconstruction.