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DMC Sinai-Grace holds 2nd annual health fair with free screenings, food, entertainment
DMC Sinai-Grace Hospital is taking patient care beyond the hospital walls and into the heart of the Detroit community.
Ad Performance And Politics Steered Brand Dollars Away From LGBTQ+ Communities – But The Pendulum Will Swing Back
The current administration discouraged many brands and organizations from supporting and marketing to the LGBTQ+ community, including in June
World Cup: our breakout XI from the group stage ⚡️
They made a name for themselves!The World Cup, even more so with 48 teams, is always an opportunity to discover new players, but also to allow others to truly make themselves known to the general publ...
Annette Bening Reelected Chair of Entertainment Community Fund; Kenny Leon Rejoins Board of Trustees
The Fund provides support and resources tailored to the needs of performing arts and entertainment professionals.
Building Community, Capacity, and Collaboration Through gmhCONNECT | Johns Hopkins Center for Global Mental Health
Doctoral trainee Yesenia Garcia shares her experience at gmhCONNECT, a training and mentoring program for global mental health researchers.
Rural Fosston moves forward in its quest to relinquish control of local hospital from Essentia Health
A northwestern Minnesota community is seeking to regain local control of its hospital, arguing Essentia Health has failed to meet local health care needs. A recent court ruling allows Fosston to take its case to arbitration.
Quality coffee, Ojibwe bonds build a business on the Fond du Lac Reservation in NE Minnesota
At a roadside kiosk on the reservation, Jackson Ripley and his family blend great coffee and Ojibwe culture together with a bit of magic. In the process, they’ve built new community ties, and they’re hoping to do more.
BUSINESS PERSPECTIVES: BerkShares Business of the Month is Bizalion’s Fine Food in Great Barrington
Bizalion’s Fine Food co-owner Jean-François Bizalion emphasizes the unexpected connections between Provence and the Berkshires, the merits of Volcanic grown olive oil, and the importance of gaining fresh inspiration through travel and of valuing your community.
A Doctor At Home: The Rise Of Ambient Home Health Monitoring
There is significant opportunity to improve long term health outcomes with ambient home monitoring.
Lagos school emerges winner of 10th Edition of Tolaram Science Challenge
By Efe Onodjae Iwerekun Community Senior High School, Ibeju-Lekki, has emerged the winner of the 10th edition of Tolaram Science Challenge (TSC), marking their third consecutive win. The school triumphed over Magbon-Alade Senior Grammar School in a keenly contested grand finale of the competition. The Tolaram Science Challenge, sponsored by Lagos Free Zone, is an annual […]
July’s Miniature of the Month and collectable coin revealed
See what you can get if you head to your local Warhammer store in July.
Federal health agency cancels most of its teen pregnancy prevention grants, including some in Pa.
A spokesperson for U.S. Health and Human Services confirmed to Stateline on Friday that the agency is canceling 53 out of 67 grants, worth about $68 million, under the Teen Pregnancy Prevention Program, affecting grantees in more than two dozen states. A list obtained by Stateline of canceled grants includes those awarded to universities, community […]
Indian Health Center’s grief vigil offers space for remembrance
Gerald L. Ignace Indian Health Center gathers local Indigenous community to find solace in remembrance and grief.
Photos: St. Louisans brought the love to PrideFest despite heat, ‘hateful’ political climate
As a weeklong heat wave settles on St. Louis, the city’s LGBTQ community was undeterred Sunday as thousands gathered to celebrate the 46th annual PrideFest downtown.
Efzimfotase alfa demonstrated improvements in bone health in treatment-naïve pediatric patients with hypophosphatasia achieving median difference of 1.67 vs placebo in RGI-C Score at week 25 in MULBERRY Phase III trial
Positive results from the MULBERRY Phase III trial showed that efzimfotase alfa (ALXN1850), an investigational enzyme replacement therapy, demonstrated a statistically significant and clinically meaningful improvement in bone health in children (2 to
Sarasota Business Awards honor innovation, entrepreneurship and the American spirit
The Greater Sarasota Chamber of Commerce recognized businesses in the community across 10 categories.
NFL players come together to shine light on men's mental health in Kensington
The initiative brings together athletes, mental health professionals, and community leaders to raise awareness about challenges like depression and anxiety.
National City weighs business tax overhaul amid mounting budget pressures
Council to hear proposal June 30. It faces significant opposition from business community.
These church members disagree on politics. Together they're wiping out medical debt
Trinity Moravian Church, a politically diverse congregation in Winston-Salem, N. C., has been raising money to retire medical debt in the surrounding community.
These church members disagree on politics. Together they're wiping out medical debt
Trinity Moravian Church, a politically diverse congregation in Winston-Salem, N. C., has been raising money to retire medical debt in the surrounding community.
NH's Business: Projected nursing shortages
Fred Kocher sits down with Chuck Lloyd with the Community College System of NH and Kimberly Perrotta with Manchester Community College to talk about working to combat a projected nursing shortage.
Pokémon GO Events This Week: June 29
Pokémon GO’s June 29 – July 5 week sees us enter the second month of the season of Forever Forward! We end June and kick off July with 10th Anniversary celebrations and Sobble Community Day! Plus the weekly rotating Raid Hours, Spotlight Hour, Dynamax Battles and Mega Raids. ⭐Highlights Raid Boss Change (July 1): Articuno, Zapdos, Moltres and […]
Michigan GOP primary for governor sees fierce fights but little debate
Michigan's primary for governor shows Republican unity on a policy agenda even as candidates fight over their loyalty to President Donald Trump.
VIA Women’s Health Collective celebrates grand opening
By Megan Dial VIA Women’s Health Collective, 17300 Westfield Blvd., Suite 330, celebrated its grand opening June 18 with the Westfield mayor, Westfield Chamber of Commerce and other community supporters. Dr. Taylor Hahn said she founded VIA Women’s Health Collective to support women in every s
Carman: Tuesday’s election is more than just a primary. It’s a colossal opportunity to change history.
The template for tyrants goes back at least to Ancient Rome and, as Nero discovered, generally ends badly.
Our picks for the best things to do in Cincinnati this week, June 29-July 5
If you're wanting to see some fireworks this week, we've got you covered. Find an event in your community to celebrate Independence Day.
Florence community rallies for local business owner diagnosed with brain tumor, here’s how you can help
The Florence community held a fundraising event for a local business owner who was diagnosed with a brain tumor for the second time.
Rooted in Flagstaff, Driven by Community
Flagstaff Business News Rooted in Flagstaff, Driven by Community
Northern AZ business stays open for community during power shutoff
Arizona Public Service cut electricity to about 8,000 homes and businesses in the Flagstaff and Grand Canyon area Saturday morning.
The Arts and Sciences of Judo: The New Edition Expands the Frontiers of Knowledge
The publication of Volume 6, Number 1 of "The Arts and Sciences of Judo" marks another important milestone in the development of judo research worldwide. As the International Judo Federation's interdisciplinary journal, under the supervision of Professor Sanda Čorak, it has become a recognised platform where science, education and the values of judo come together to deepen our understanding of the many dimensions of our sport. It also forms an integral part of the IJF Academy's mission to promote education, lifelong learning and the dissemination of knowledge throughout the global judo community.
Team USA Basketball Showcase celebrates youth sports
The Team USA Basketball Showcase tipped off on Saturday featuring community, camaraderie, and a continuing commitment to youth sports.
Video: Juneteenth Fest brings vendors, entertainment to Killeen Special Events Center
The Black Chamber of Commerce hosted its Juneteenth Fest Saturday at the Killeen Special Events Center from 11 a.m. to 3 p.m. The event featured local vendors, community resources and
Community baby shower in Landover aims to address disparities, promote healthier lifestyles
This weekend in Prince George’s County, people came together for a community baby shower aimed at promoting healthier lifestyles among Black and Brown families across the DMV. With a lot of energy and laughter in the room, hundreds of people gathered at Prince George’s Sports and Learning Complex in Landover. The free event offered support for expecting mothers and parents…
San Antonio Pride festival celebrates LGBTQ+ community, raises money for local nonprofits
Thousands of people were expected at Crockett Park on Saturday for the Pride Bigger Than Texas Festival, an eight-hour celebration of LGBTQ+ history, resilience and community support.
Arizona health officials investigate suspected pneumonic plague case
Yavapai County Community Health Services said Friday that a county resident is thought to have contracted the infection.
Stephenson Business Center highlights local vendors, gives back to community
The Stephenson Business Center holds a community event Saturday with dozens of vendors and some giveaways for area residents.
Community Market Series creates space to support small business
A new market in Boardman is hoping to bring the community together to help support small, local businesses.
Community Harvest receives $5,000 grant from the St. Joseph Community Health Foundation
Community Harvest Food Bank received a $5,000 grant from the St. Joseph Community Health Foundation.
Business owners: The future of downtown is a stronger State Street
Businesses for State Street is made up of business owners and members of the Santa Barbara community. We write to respectfully ask that the mayor and City
Community helps rebuild Future Champions Sports Complex
Now, one year after the disaster, Jamison said he reflects on the support he was shown.
Central NY farm in business for more than 80 years faces costly rebuild after fire
Community members and farmers have rallied to help the farm cleanup and rebuild after a fire destroyed its greenhouses.
Louisiana Art and Science Museum took guests back in time at its annual Dino Day
BATON ROUGE — The Louisiana Art and Science Museum gave guests an opportunity to experience a time long passed at its annual Dino Day on Saturday.
Businesses across Oahu prepare to close as rising costs strain operations
Community members say the closures are difficult to watch, especially as familiar businesses continue to disappear across the island.
Chicago teacher visiting every FBS stadium while bridging gap between LGBTQ+ community, sports world
A Chicago teacher is hard at work on his quest to visit every NCAA Division I Football Bowl Subdivision stadium in America, while also strengthening bonds between the sports world and the LGBTQ+ community.
Trump news at a glance: president tests out a new ‘red scare’ ahead of midterms
Republican strategists believe rise of Mamdani could present opportunity to tag Democrats with most extreme views of the left – key US politics stories from Friday 26 June
Saturday Pre-orders: Battleforces, Ciaphas Cain, and the Age of Darkness
Check out all of today’s new pre-orders for Warhammer 40,000, Warhammer: The Horus Heresy, and Black Library.
Business Honor Roll picnic celebrates community support
The Business Relations Committee at MyMichigan Medical Center Alpena recently welcomed local professionals and industry leaders to a Business Honor Roll Appreciation Picnic hosted by Alpena Agency in their downtown location. Established in 1994, the Business Honor Roll brings together local companies and corporations interested in strengthening health care for our region. Through annual contributions […]
Cool Desert Nights returns to Richland with classic car show, entertainment
RICHLAND, Wash. — One of Tri-Cities’ biggest events, Cool Desert Nights, returns to Richland with a weekend of classic cars, live entertainment, food and community events.
Police seek help identifying suspect in California Avenue business break-in
The Bakersfield Police Department is asking for the community’s help in identifying a man accused of breaking into a business on California AvenuePolice said it
I Took My 12-Year-Old Dog to See 'Supergirl' and It Completely Changed the Movie for Me
Like many dog owners, I'm fully aware that my dog is the best dog. So when the chance to see the buzzy new 'Supergirl' with my 12-year-old Chihuahua-mix arose, I jumped at the opportunity.I was not prepared for how his presence would affect my review of the film.
How SBT navigated the politics of GRVL
Real community engagement and substantive changes paved the way for SBT GRVL's continued success.
Sturgeon City unveils ‘STEAM on the Go’ mobile science bus
The bus is designed to bring hands-on science lessons directly to local schools and community events.
Essentia again ranks among Minnesota's best for quality care
Minnesota Community Measurement (MNCM) — a statewide resource providing timely, comparable information on healthcare quality, costs and equity — once again ranks Essentia Health as a quality leader in its annual Health Care Quality Report.
Meet Lara Pires, Valedictorian at Community Academy of Science and Health
Meet Lara Pires, Valedictorian at Community Academy of Science and Health
From Linchpin to Lever — Part 1: Measuring Trust in Public Health
Learn how local health departments can measure public trust using existing public health tools to strengthen relationships and improve community health outcomes.
Community Challenge Chaos Spreads
To celebrate the release of the Chaos Cubed game drop, the mayhem continues with our Chaos Spreads Community Challenge! Unite with your friends and play with the free add-on reward, courtesy of completing the Chaos Sparks Community Challenge. Players can collectively win a new Bedrock world for all from Blockception!
Black Health and Wellness Association holds event to provide healthcare options in North Omaha
Watch: The Black Health and Wellness Association hosted a community night to provide healthcare resources for North Omaha residents.
CSUF Report Finds Family Businesses Drive Jobs and Revenue in Fullerton
The city of Fullerton is home to a vibrant entrepreneurial community, with family-owned businesses serving as a cornerstone of the local economy. The family business sector in Fullerton is the subject of a new report researched and published by Tim Schultz, the head of Cal State Fullerton’s Center for Family Business. Chethan Srikant, associate professor […]
Texas Democrats meet for convention amid questions about party unity
Democrats see state Rep. James Talarico, D-Austin, as the best opportunity to flip the long-held Republican U.S. Senate seat and want to see how he will win over Black voters.
Council Explores AI, Quality Improvement and Patient Safety to Advance Community Health
The MHA Council on Health Access and Community Impact held its final meeting of the program year June 4 to examine emerging opportunities and challenges shaping healthcare delivery and advancing community health.
810 Entertainment to bring bowling, games and more to Austin EastVillage
A new entertainment hub is headed to Northwest Austin in early 2027.
Business Leader Tim Giroux Announces Candidacy for Nevada Joint Union High School District Trustee
GRASS VALLEY, Calif. – June 26, 2026 – Tim Giroux, a business leader and community member rooted in the Auburn/Grass Valley area since 1999, today announced his candidacy for Trustee of the Nevada Joint Union High School District. The election will be held in November 2026. Giroux brings more than 40 years of business ownership […]
KXNO layoffs leave Iowa sports community too quiet
This week's layoffs of local sports radio talkers leaves our sports community worse off, columnist Travis Hines writes.
Bank of America community roundtable highlights sales tax increase, small business struggles
Business and government leaders also discussed hiring trends and the importance of the Charlotte Douglas International Airport.
'A heavy impact:' Schwebel's closure leaves a sense of community loss
It’s the small things that residents across the region will remember when Schwebel’s closes its doors at summer’s end. Everything from...
Thieves are breaking through drywall to burglarize Chicago businesses, police warn
Chicago police issued a community alert on Thursday warning that several businesses have been burglarized by thieves who broke in through the drywall.
The Big Summer Preview – New Ork miniatures and codex are coming
Updated Trukk, Mek and Warboss are on the horizon.
The Big Summer Preview – Chaos Arrives in the Old World
New miniatures, rules, and more revealed for Warhammer: The Old World.
The Big Summer Preview
New jetbikes, grav vehicles and Dreadnoughts revealed for Warhammer 40,000 AND Warhammer: The Horus Heresy.
The Big Summer Preview
See the new edition of Necromunda revealed, including miniatures, rules, and more.
The Big Summer Preview – A New Animation: The Butcher’s Nails
Witness a World Eater in the grip of the Butcher’s Nails.
The Big Summer Preview – See all the reveals here
New reveals for Warhammer 40,000, Kill Team, Age of Sigmar, and more.
The Big Summer Preview – New Starter Sets and ready painted terrain
Dive into Warhammer 40,000, and fight on the battlefields of Armageddon with new terrain kits.
City council members request special meeting on planned Sports and Entertainment District
San Antonio Council Districts 1, 5 and 7 want a special meeting before Aug. 7 to guide public input on the Spurs arena’s $75M Community Benefits Agreement as the city considers a $489M Sports and Entertainment District.
Monkey Business: Wild rhesus macaque spotted at Mount Dora hotel
A wild rhesus macaque was spotted at the historic Lakeside Inn in Mount Dora, Florida, spending about 45 minutes roaming the property and attracting attention from guests and staff. The hotel and local businesses responded with humorous, monkey-themed social media content, engaging the community. Wildlife officials cautioned the public not to approach or feed wild monkeys due to potential health risks and encouraged reporting sightings to authorities. The monkey has not returned to the hotel but has been seen elsewhere in downtown Mount Dora.
Plaucheville business opens parking lot to Red Cross, polling site after flooding
One week after Avoyelles Parish received nearly 30 inches of rain in less than 12 hours, 2 Sisters’ Salsa is opening its parking lot to help the community recover.
Plaucheville business opens parking lot to Red Cross, polling site after flooding
One week after Avoyelles Parish received nearly 30 inches of rain in less than 12 hours, 2 Sisters’ Salsa is opening its parking lot to help the community recover.
Men’s Health Month reminds community members to catch up on overdue wellness visits
June is Men’s Health Month and experts are urging men not to ignore crucial preventative care.
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
Following IAM Union Advocacy, Kansas PERB Orders Count of Timely Cast Ballots in KU Health System Pharmacy Technician Union Election
KANSAS CITY, Kan. — Following weeks of advocacy from the IAM Union, Pharmacy Technicians, elected officials and community supporters, the Kansas Public Employee Relations Board (PERB) has ruled that 37 previously uncounted ballots will be included in the final tally of the recent union representation election involving Pharmacy Technicians at the University of Kansas (KU)
Fulton County health officials notify Johns Creek High School community of possible tuberculosis exposure
Students and staff who may have had close contact with the individual will receive separate notifications and be offered free tuberculosis testing.
Edgefield County health fair offering free screenings, vendors, and entertainment
JOHNSTON, S.C. (WJBF) — A free community health fair is headed to Edgefield County. “Prevention Today for a Healthier Tomorrow,” set for Friday, June 26 from 10 to 1 at Strom Thurmond High School i…
Consumer Discretionary Stocks Drawing Institutional Rotation Into Live Entertainment Leaders
With the Federal Reserve hinting at a pause in rate hikes, stubborn inflation still in the background, and several large companies surprising on earnings, consumer discretionary stocks are back in focus for investors weighing risk and opportunity. This article looks at how that mix of easier policy signals, solid corporate reports, and ongoing geopolitical and supply chain issues could affect larger U.S. consumer-focused companies. It will walk through 3 stocks from a curated screener that...
How Caesars’ Expanded Tribal iGaming and Community Partnership Could Shape Caesars Entertainment (CZR) Investors’ Outlook
In June 2026, Caesars Entertainment Inc. announced that it had expanded its partnership with three Wabanaki Nations in Maine to cover online casino gaming, aiming to launch Caesars Palace Online Casino, Caesars Sportsbook & Casino and Horseshoe Online Casino in 2026, subject to regulatory approval and integrated with Caesars Rewards and a universal digital wallet. A distinctive element of this agreement is Caesars’ commitment to employ and train tribal members while providing financial...
Kaiser Permanente highlights its dedication to LGBTQ+ health
Daniel Woody, Chief Administrative Officer for Kaiser Permanente San Francisco, joined Midday Live to talk about why the organization continues to show up for Pride, and how it supports the LGBTQ+ community year-round.
New program aims to bring more business to downtown Buffalo
The initiative will provide grant money to allow local groups and businesses to host community focused events in the downtown area.
New Health Sciences Provost Named
Wake Tech Community College is pleased to announce that Dr. Jennifer Bray has been selected as the next Provost of the Perry Health Sciences Campus.
Free Fireworks and Live Music at Herkimer College
Herkimer County Community College is bringing the community together for the Herkimer County Fire in the Sky Palooza at Wehrum Stadium.
York, Community Unite for Hands-On Environmental Science Journey
A group of students, faculty, and Southeast Queens residents recently traveled from the York College campus to the waterfront campus of Kingsborough Community College (KCC) in the Manhattan Beach neighborhood of Brooklyn to set sail in the Research Vessel CUNY1 on Jamaica Bay, and to explore a part of the Hudson Raritan Estuary system.
Health Union Launches 2027 Innovation Suite, Pairing Community Leadership with AI to Accelerate Patient and HCP Connections
/PRNewswire/ -- Health Union, the pioneer in online health communities operating 125+ condition-specific sites reaching over 50 million patients and 9.5...
CVS Health Foundation invests $1 million in Rhode Island nonprofits tackling community health needs
/PRNewswire/ -- The CVS Health Foundation is investing $1 million in grants through its Hometown Fund to 20 organizations that are making a difference for...
Byram says he’s ready for new opportunity as the top defenseman for Blackhawks
Bowen Byram is stepping in as Chicago’s No. 1 defenseman after he was acquired in a trade with the Buffalo Sabres on Tuesday night.
Bacteria-killing viruses redirect vaccine immunity to destroy cancer
Phages, viruses that infect bacteria, could be genetically manipulated to destroy cancerous cells using the immunity we have acquired from vaccines
America’s Friendship Recession Has Become a Startup Opportunity
A new “connection economy” is selling courses, clubs and confidence bootcamps to socially isolated adults, but scaling intimacy remains a challenge.
In wake of homicide on Tyler Street, nearby business owners reaffirm faith in community
In the aftermath of last week’s homicide on Tyler Street, local business owners in the area told The Eagle that the incident is not representative of the neighborhood’s character.
Nominations Open for 2026 Centre County Business Awards
Nominations are now open for the Chamber of Business and Industry of Centre County's 2026 Centre County Business Awards, and community members are invited
CVS Health Foundation invests $1 million in Hartford nonprofits tackling community health needs
Local organizations receive Hometown Fund support to expand access to health care, food, housing and essential services