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Tarrytown spa undergoing repairs after SUV crashed into business
Repairs are underway at a Tarrytown spa after an SUV crashed into the business. The business hopes to reopen in early May.
Local garage door repair business, customers targeted by nationwide scam
Fallout from a nationwide trend of garage door repair scams showed up at the doorstep of Ray and Brad Larson in the form of angry customers they never heard of.
Relationship with Trump may be beyond repair, Keir Starmer told
PM gets widespread backing after president’s mocking impersonation takes US-UK relationship to new low
Scientists discover hidden “winds” inside cells that could explain cancer spread
Cells aren’t as passive as scientists once thought—they actively create internal currents to move proteins quickly and efficiently. These “cellular winds” push materials to the front of the cell, enabling faster movement and repair. Discovered by chance and confirmed with advanced imaging, this system challenges decades of textbook biology. It may also reveal why some cancer cells spread so rapidly.
Back to Business Program helps Quynh’s Pharmacy continue serving Little Saigon community
Quynh’s Pharmacy is a fixture in Little Saigon. The owner, Mary Bui, is also a fixture within the pharmacy, having worked there for three decades. When vandals broke the glass entry door and both security gates, Bui faced a steep bill to repair the damages. “They charged over $6,000,” she explained. “We had to do […]
Better Business Bureau warns of spring and summer scams targeting homeowners
The BBB's scam tracker shows some New Yorkers have lost nearly $12,000.
Weizmann Institute rebuilds after Iranian missile strike, but lost science may be gone for good
Most buildings damaged in the June 2025 attack have been repaired, but destroyed research and data cannot be recovered.
Understanding protein motion could greatly aid new drug design
For many of us, “protein” is the key element of a food order. However, beyond your preferred choice of meats or plant-based alternatives, proteins encompass a large class of complex biomolecules whose chemical structure is encoded in our genes. Proteins have critical functions in living cells: They help repair and build body tissues, drive metabolic reactions, maintain pH and fluid balance, and keep our immune systems strong.
The Tampa Bay Rays juggle roster moves, stadium politics and new fan perks ahead of Opening Day
The Rays return to Tropicana Field under a new roof on April 6.
Israel hinders repair of damaged water infra deepening Gaza’s health crisis
Accrington Victoria Hospital site to become health and care hub
Accrington Victoria Hospital closed in 2024 after the building was found to be beyond repair.
Scientists say NAD+ could slow aging and fight Alzheimer’s and Parkinson’s
A global team of leading scientists is zeroing in on a tiny but powerful molecule that could reshape how we age. Known as NAD⁺, it plays a crucial role in keeping our cells energized, repairing DNA, and maintaining overall health—but its levels steadily decline over time, potentially fueling diseases like Alzheimer’s and Parkinson’s. Researchers are now exploring ways to boost NAD⁺ using compounds like NR and NMN, with early studies hinting at improvements in memory, metabolism, and physical function.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
U.S. health care system is beyond repair
Letters to the editor for Sunday, March 22, 2026
Vehicles damaged in West Allis car wash; business to pay for repairs
Four people say their vehicles were damaged at the Tsunami Express Car Wash in West Allis on Feb.10. They told Contact 6 their vehicles were scratched and two cars' back windows were smashed.
Customers help Denver small business owner relocate after 60-day vacate notice
Denver electronics repair business receives support after being force to leave workshop
iFixit Tears Down the iPhone 17e, Discovers MagSafe Upgrade Path for iPhone 16e Owners
Repair site iFixit today took apart the iPhone 17e, which is the new low-cost iPhone that Apple launched last Wednesday. The iPhone 17e is almost identical to the iPhone 16e in design, but it does include a MagSafe back panel that supports MagSafe and faster Qi charging than the iPhone 16e. When disassembling the iPhone 17e, iFixit found that the MagSafe panel for the device is the same size as the panel for the 16e, and the two are interchangeable.
Kennedy Center votes to shut down operations for 2 years and names a new president
The widely expected decision comes in the wake of numerous resignations and cancellations during President Donald Trump's second term, although Trump himself has cited the need for repairs as a reason for the closure.
Rare blower RTX 5090 AI card repaired by cutting memory from 32GB to 28GB
Brother Zhang fixes AI RTX 5090 card by cutting memory-bus An interesting card, and an interesting fix. This RTX 5090 for AI was made at your gaming
This Printed Zipper Repair Requires No Unsewing
If a zipper breaks, a 3D printer might not be the first tool one reaches for — but it’s more feasible than one might think. [MisterJ]’s zipper slider replacement is the kind of 3D…
Scientists discover ALS protein that links DNA repair to cancer and dementia
A protein tied to ALS and dementia may have a much bigger role in disease than scientists realized. Researchers found that TDP43 controls a key DNA repair process, but when the protein becomes imbalanced, the repair system can spiral out of control, harming neurons and destabilizing DNA. The team also discovered that high levels of the protein are linked to increased mutation rates in cancer. The discovery places TDP43 at the center of both neurodegeneration and cancer biology.
The MacBook Neo is ‘the most repairable MacBook’ in years, according to iFixit
Apple’s new MacBook Neo isn’t just the most affordable MacBook — it’s also the company's most repairable laptop in “about fourteen years."
Apple MacBook Neo emerges as company’s most repairable laptop in more than a decade
Apple's MacBook Neo, the laptop it announced last week that starts at $499 for students, is the most repairable laptop the company has released since 2014, according to an analysis released Friday by iFixit.
April 1 Is Next Possible Launch Date For Moon-Bound Mission Following Repairs
The space agency has updated the list of the next possible launch dates.
First MacBook Neo teardown praises 'absolutely amazing' repairability
"No sticky tape, no tricky adhesives, modular parts... it's just super straightforward, elegant design."
MacBook Neo Teardown: Modular Ports, Glue-Less Battery, Zero Tape
A teardown of the new MacBook Neo by Australian YouTube repair channel Tech Re-Nu reveals what may be the most modular and repair-friendly Mac laptop in recent times. The Neo is shown being taken apart in just six minutes, suggesting Apple has prioritized simplicity across the board, using standard Torx screws (T3, T5, and T8) and a clean cable routing design. To open the aluminum body, eight screws on the bottom are loosened, similar to the MacBook Air and MacBook Pro.
Here’s how much a MacBook Neo repair will cost you
If you’re considering buying the new MacBook Neo, whether for yourself or a family member, it may be helpful to know how much repairs will cost.
In Russia’s Former Capital, Restoring the Past to Survive the Present
With political activism off-limits, residents of St. Petersburg are finding purpose and community in the “politics of small deeds,” repairing and cleaning architectural treasures.
'It was a deal': Bellingham native buys Pacific Science Center's stegosaurus head for thousands
A Bellingham native invests in the Pacific Science Center's stegosaurus head as the dinosaur exhibit faces closure and disrepair.
St. Peter's announces closure of Albany nursing home
The closure of the facility after nearly seven decades is the result of the building needing tens of millions of dollars in repairs, the health network says.
Scientists create cartilage scaffold that helps the body regrow bone
Researchers in Sweden have engineered a cell-free cartilage scaffold that can guide the body to rebuild damaged bone. By removing the cells but preserving the structure and natural growth signals, the material acts as a blueprint for the body’s own repair process. In animal studies, it helped regenerate bone without triggering strong immune reactions. The team now plans to scale up production and begin testing the approach in humans.
Cracker Barrel Works to Repair Its Business
Cracker Barrel reported lower profits and revenue in its latest quarter, but its CEO said efforts to turn around the restaurant chain are taking shape.
Medical journal The Lancet blasts RFK Jr.’s health work as a failure
Kennedy's destruction "might take generations to repair," The Lancet said.
'One year of failure.' The Lancet slams RFK Jr.'s first year as health chief
In a scathing review, the top US medical journal's editorial board warned that the "destruction that Kennedy has wrought in 1 in office might take generations to repair."
California GOP lawmakers are incensed over a gas tax study bill. Rural groups say they need it
As more electric vehicles hit the road, California could collect billions less from gas tax revenue to repair them. But even a bill to study options could be a huge political lift for Democrats.
State Farm announces refund for car insurance customers
State Farm Mutual announced it will distribute $5 billion dividend to customers across 49 million vehicles due to lower collision rates and reduced auto repair costs.
Guilty: Cellphone repair business owner paid girls for videos of sex acts, cutting
The owner of a now-shuttered cellphone repair business pleaded guilty in U.S. District Court in Tallahassee to charges involving the sexual exploitation of underage girls.
US democracy has repaired itself before. Here’s how we can do it again.
Every 60 years, America remakes itself. We’re due.
Will team owner greed prevail over the public good in Ohio sports facility financing? Editorial
At a minimum, any publicly funded gilding of the Guardians’ and Cavs’ resources for facility upgrades should be paired with a required renegotiating of the facility leases to take local taxpayers off the hook for any further obligation to pay for repairs and upgrades, writes the editorial board of The Plain Dealer and cleveland.com.
Olaplex links with ‘SNL’ star to blend science, style and humor in new ads
Chloe Fineman serves as Chief Hair Officer for “Science Never Looked So Good,” a campaign that promotes the hair care brand’s bond repair treatment.
Scientists reverse muscle aging in mice and discover a surprising catch
A UCLA study in mice reveals that aging muscle stem cells accumulate a protein that slows repair but boosts survival. This protein, NDRG1, acts like a brake, preventing cells from activating quickly after injury. When researchers blocked it in older mice, muscle healing sped up dramatically — but stem cells became less resilient over time. The work suggests aging may reflect a survival trade-off rather than straightforward decline.
Scientists reveal how exercise protects the brain from Alzheimer’s
Exercise may sharpen the mind by repairing the brain’s protective shield. Researchers found that physical activity prompts the liver to release an enzyme that removes a harmful protein causing the blood-brain barrier to become leaky with age. In older mice, dialing down this protein reduced inflammation and improved memory. The discovery points to a surprising body-to-brain pathway that could inspire new Alzheimer’s therapies.
Bring out the shy people: The case for politics without politicians
In a new book, political theorist Hélène Landemore argues that electoral politics is irredeemably broken but that democracy can be repaired by empowering ordinary people to govern.
How hibernating hamsters could help astronauts
Special cells can repair muscles, even when some animals are dormant.
Secrets Behind Rome's Self-Healing Concrete Leads Scientist to Launch Roman-Style Concrete Business
A scientist who figured out the secret behind ancient Rome's self-repairing concrete has recently confirmed his theory at a Pompeii building site
Scientists Grew Mini Human Spinal Cords, Then Made Them Repair After Injury
One day, this could change lives.
3 ways UC science is healing broken hearts
UC labs are developing new treatments that don’t just prevent damage from getting worse, but — for the first time in medical history — actually help the heart heal.
Talking politics with family: We won't make it if we don't 'put our hearts and heads together'
This episode of One Small Step reflects on how political polarization can strain family relationships and how trying to build connections across political lines can help repair that divide.
Residents raise health concerns at Northeast Houston apartment complex
Residents at Houston’s Drysdale Village Apartments are calling for urgent repairs and health inspections following reports of severe rodent infestations, mold, and raw sewage leaks at the complex.
Wyoming Small Business Owners Outline Top Priorities for 2026 Legislative Session
Right to Repair, stiffer penalties on theft, and eminent domain reform are among the top priorities for Wyoming small business owners
York County firefighters extinguish vehicle fires at diesel repair business
Angry girlfriend smashed RTX 3080 Ti, but a repair shop managed to save the GPU
Smashed graphics card gets a second chance Colorful RTX 3080 Ti repair video shows GPU swap test after cracked PCB and burned VRAM power part A Chinese
Vermont man turns hobby into accordion repair business
A 74-year-old Vermont man has found his passion not just in playing the accordion, but in fixing them. Nathan Longo is one of a handful of people who work on accordions in New England.
Social media broke political discourse. Civil service could repair it.
It should not come as a shock that American politics has become hostile, volatile, tribal, and polarized. These are all symptoms of overuse of technology that indulges and force-feeds our worst assumptions about each other.
Chicago mother claims unsafe conditions in apartment are harming her children's health
A mother of four living in a subsidized housing apartment on the 4800 block of North Avers says unsafe conditions inside her unit are putting her children’s health at risk — and despite months of repair requests, she says little has changed.
From war damage to heart repair: ERC grantees supported to turn their science into practice
The European Research Council (ERC) has published the outcomes of the last 2025 round of its Proof of Concept Grants. In this round, 136 grantees will each receive €150 000, supporting them in exploring how their scientific results can move towards practical application or early commercial use. With these awards, the total number of Proof of Concept Grants under the ERC 2025 Work Programme reached 300, representing an overall budget of €45 million. The scheme is funded under Horizon Europe, the EU’s framework programme for research and innovation.
Mobile home, trailer repair business burn on Tyler loop
Tyler firefighters responded to a commercial fire Sunday, with at least one building engulfed upon arrival.
This Picture Of A Nissan CrossCab Repaired With Spray Foam Insulation Is A Terrifying Warning
As I’m sure you’re aware, we here at the Autopian have a company car: our ridiculous Nissan Murano CrossCab, which we’ve half-wrapped in Xpel protective film and then done all sorts of dumb stuff with. It’s been a hell of a lot of fun, perversely, and people seem to really enjoy seeing this strangely improbable […]
You Must Leave! Binghamton Plaza Shop Owners Have Been Warned
The husband and wife who've operated Leather Corner Shoe Repair in Binghamton for nearly 54 years have been officially advised to leave the building.
Johnson Health Tech Expands Recall to Include Matrix Retail and Vision Treadmills Due to Fire Hazard
Consumers should inspect their treadmills to confirm whether they have a power cord bracket installed on the unit. If there is no power cord bracket, consumers should ensure that the power cord is completely inserted into the treadmill’s power socket before each use, until the treadmill is repaired. Consumers should contact Johnson Health Tech North America to receive a free replacement power cord with an automatic locking-style plug by mail for self-installation. To facilitate consumer participation in this recall, the installation of the replacement power cord does not require any tools.
While St. Pete Beach residents were locked out after Hurricane Helene, the Mayor was already having repairs done
Video captured by a resident the day after the hurricane shows a crew already working at Petrila's home.
This new building material pulls carbon out of the air
A new building material developed by engineers at Worcester Polytechnic Institute could change how the world builds. Made using an enzyme that turns carbon dioxide into solid minerals, the material cures in hours and locks away carbon instead of releasing it. It’s strong, repairable, recyclable, and far cleaner than concrete. If adopted widely, it could slash emissions across the construction industry.
Scientists discover why some wounds refuse to heal
Scientists have uncovered a surprising reason why some chronic wounds refuse to heal, even when treated with antibiotics. A common bacterium found in long-lasting wounds does not just resist drugs. It actively releases damaging molecules that overwhelm skin cells and stop them from repairing tissue. Researchers discovered that neutralizing these harmful molecules with antioxidants allows skin cells to recover and restart healing.
Google is exploring a much better way to build batteries into phones
Less glue = easier repairs.
Olive Chapel Road closure in Apex slows local business
After severe flooding in Apex on August 6, 2025, a sinkhole formed on Olive Chapel Road, closing it for repairs and significantly affecting local businesses.
Maine House votes to override Mills’ veto on right to repair bill
During House debate on Tuesday, the issue cut across party lines with Democrats and Republicans arguing both sides of the issue.
The Pros And Cons Of The Chevy Corvette's Carbon Fiber Wheels
Carbon fiber wheels are lighter and can change the driving experience, but they're also much more expensive, and difficult to repair if they're damaged.
From Rollable Screens to Repairable Powerhouses: The 8 Laptops That Stole CES 2026
This year's CES was a processor palooza, spawning several new AI PC laptops. We spent time with dozens of notebooks in Las Vegas, and these are our favorites across eight key categories.
Just 10 minutes of exercise can trigger powerful anti-cancer effects
A brief, intense workout may do more than boost fitness—it could help fight cancer. Researchers found that just 10 minutes of hard exercise releases molecules into the bloodstream that switch on DNA repair and shut down cancer growth signals. When these molecules were applied to bowel cancer cells, hundreds of cancer-related genes changed activity. The discovery helps explain how exercise lowers cancer risk and hints at future therapies inspired by movement.
These Are the Coolest Laptops We've Seen at CES 2026
Laptops this year will get new processors, but many computer makers are turning back the clock with designs that are easier to repair and upgrade.
UPDATED: Heat Restored at Oneida Rec Center
The Oneida Rec Center is closed due to a delay in the delivery of a crucial part needed to repair the boiler.
Harrisburg Mayor Wanda Williams committed to revitalizing the city by modernizing infrastructure
Williams outlined her administration's priorities for the next four years, which include infrastructure projects such as repairing roads, bridges, and streets.
California bill increases penalties for fake liens used to harass politicians, businesses
A California lawmaker introduced a bill Monday to crack down on fake liens filed against politicians, court employees and businesses that can force victims to spend thousands of dollars in legal fees to clear their names and repair their credit.
This CRISPR breakthrough turns genes on without cutting DNA
A new CRISPR breakthrough shows scientists can turn genes back on without cutting DNA, by removing chemical tags that act like molecular anchors. The work confirms these tags actively silence genes, settling a long-running scientific debate. This gentler form of gene editing could offer a safer way to treat Sickle Cell disease by reactivating a fetal blood gene. Researchers say it opens the door to powerful therapies with fewer unintended side effects.
A picture is emerging of how US sees its role ‘running’ Venezuela
President Donald Trump’s administration is working quickly to establish a pliant interim government in Venezuela following the dramatic capture of Nicolás Maduro, according to US officials, prioritizing administrative stability and repairing the country’s oil infrastructure over an immediate turn to democracy.
Klarna Sees Triple-Digit Spending Growth Across Entertainment, Experiences, and Automotive This Holiday Season
NEW YORK, December 23, 2025--Klarna, the global digital bank and flexible payments provider, today reports an increase in U.S. holiday spending beyond traditional retail, with consumers driving triple-digit year-over-year growth across entertainment (+130%), experiences (+115%) and automotive products (100%), such as vehicle maintenance and repairs, from December 1 through Monday, December 22, signaling a clear shift toward experiential and high-value practical purchases this season.
Adam Schefter Issues Brutal Report Regarding Steelers’ T.J. Watt
The Pittsburgh Steelers can’t seem to avoid bad news when it comes to linebacker T.J. Watt. Watt, who underwent successful surgery to stabilize and repair a partially collapsed lung that was suffered during a dry needling treatment session at the facility two weeks ago, was ruled out earlier this week for Sunday’s matchup with the Detroit Lions […]
Hot Springs gets 2nd $25,000 check from business for Helene recovery
For the second straight year, Dental Advocacy Group gifted Hot Springs $25,000, which will primarily be used to help repair 14 Hot Springs area homes.
Chiefs QB Patrick Mahomes has surgery to repair torn ACL after second opinion, coach Andy Reid optimistic about quick return
Repairs needed after business hit-and-run
SCRANTON, LACKAWANNA COUNTY (WBRE/WYOU) — A family-owned business in Scranton is reeling after a hit-and-run crash that badly damaged their property. The owners are now looking for answers, hoping someone will come forward. The family told 28/22 News while there have been instances when someone sideswiped their fence, they’ve never seen anything quite like this […]
Auto repair business heavily damaged by fire in Cicero
A Chicago-area auto repair business was heavily damaged after a fire broke out Thursday.
Google will repair Pixel 9 Pro phones with display issues
Google is fixing display issues with its Pixel 9 Pro series.
Fairbuds XL Gen 2 bring improved drivers, ANC and battery while retaining modular design
Fairphone's latest over-ear headphones are built with repairability in mind. Over two years since launching its first over-ear headphones, Fairphone has a...
iFixit Put a Chatbot Repair Expert in an App
FixBot can check on the health of your devices and talk you through necessary repairs. You can even point your phone's camera at broken gear to get started.
iFixit Launches Free iOS Repair App With AI-Powered FixBot
iFixit today announced the launch of a new iFixit app that's available to download from Apple's App Store (and the Play Store on Android devices). It includes all of the iFixit repair guides in a format that's ideal for mobile devices, along with a workbench that keeps track of repairs, a battery lifespan predictor, and an AI repair buddy called FixBot. The iFixit repair app is able to monitor an iPhone's battery in real time, providing graphs of how a battery deteriorates over time.
iFixit’s FixBot helps with repairs ‘the way a master technician would’
Trained on iFixit’s own repair guides.
Google Pixel 9 Pro display woes lead to extended repair program
Pixel 9 Pro Fold gets a warranty extension
Space is filling with junk and scientists have a fix
Earth’s orbit is getting crowded with broken satellites and leftover rocket parts. Researchers say the solution is to build spacecraft that can be repaired, reused, or recycled instead of abandoned. They also want new tools to collect old debris and new data systems that help prevent collisions. The goal is to make space exploration cleaner and more sustainable.