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World Health Assembly endorses resolution on precision medicine
At the Seventy-ninth World Health Assembly, Member States endorsed a new resolution on Precision medicine: a path towards targeted, personalized and equitable care, taking an important step towards advancing precision medicine as part of efforts to strengthen equitable, effective and sustainable health systems. Precision medicine refers to the use of clinical, molecular, genomic and other health data to inform prevention, diagnosis and treatment, taking into account variability while applying appropriate ethical and legal safeguards. When integrated responsibly into health systems, precision approaches can improve outcomes across different disease areas and across the life course – from cancer and rare diseases to infectious diseases, maternal, newborn and child health, mental health and noncommunicable diseases. The resolution reflects rapid advances in genomics, diagnostics, data science and digital health, alongside widening global inequities in access to these innovations. Many populations – particularly in low- and middle-income countries – remain underrepresented in data and research, limiting the public health impact of precision medicine and risking the widening of health disparities if action is not taken now. "Precision medicine is not an aspirational idea for health delivery in the future – it is already transforming lives across the world. But its benefits remain out of reach for too many and the research driving progress is concentrated in high income countries. This WHA resolution gives global health leaders, ministries of health, and WHO a clear mandate: to act. From infant screening to setting up genomic databases WHO will work with countries to bring about the power of these innovations." Dr Meg Doherty, Director Science for HealthThrough the resolution, Member States commit to developing and strengthening national policies, infrastructure, workforce capacity and governance frameworks to support the safe, ethical and equitable integration of precision medicine into health systems, aligned with universal health coverage. This includes promoting affordability, ensuring inclusive research and data systems, strengthening regulation and data governance, and fostering collaboration across sectors and regions.WHO is requested to provide technical and normative support, review and coordinate existing guidance, facilitate global and regional collaboration, and develop a Global Strategy on Precision Medicine to guide equitable and context‑appropriate implementation. WHO stands ready to support Member States through tools such as a country maturity model for countries to self-assess capacity in implementing precision medicine depending on their context. In the immediate term WHO will map all existing guidance and frameworks and host extensive consultations with interest holders globally.By placing equity, inclusion and public value at the centre of precision medicine, the resolution reinforces WHO’s commitment to ensuring that scientific advances benefit all people, everywhere, and that no one is left behind in the next era of health innovation."By uniting people-centered healthcare with innovation, precision medicine has the potential to transform lives. This resolution helps ensure those advances serve the shared goal of health for all." Dr Sylvie Briand, Chief Scientist For further information please visit the Health Topic: Genomics
Hubble Captures Galaxy Cluster
Hubble captured this scene of galaxy cluster MACS J1141.6-1905 in visible and infrared light. The cluster is around four billion light-years away.
UN’s climate crisis vote shows political momentum is growing, say experts
Resolution backed by 141 states hailed as ‘new chapter’ that could improve climate diplomacy and litigation efforts
Even Republican Stomachs are Turning at Trump’s Latest Sweetheart Deal
The whole arrangement smells like week-old mackerel in a noonday suit. But it might not be illegal—unless GOP majorities in Congress decide to make it so.
The Science Behind the Quest for a Non-Peptide Oral Weight Loss Drug
Not only does it have a tongue-twisting name, “orforglipron” has a complex molecular structure that made its synthesis very challenging. A massive effort by chemists at the Eli Lilly pharmaceutical
College of Pharmacy & Health Sciences to host statewide symposium - News
The Campbell University College of Pharmacy & Health Sciences will welcome healthcare leaders, educators, pharmacists and students from across North… More on this post
Codex for Mac updated with new Appshots feature that instantly gives chat context
OpenAI just released this week’s Codex desktop app update, and it includes a brand new feature on Mac called Appshots....
Quantum supremacy just ran into an unexpected rival: An ordinary laptop armed with new math
Using a conventional computer and cutting-edge mathematical tools and code, physicists at the Center for Computational Quantum Physics (CCQ) at the Simons Foundation's Flatiron Institute and collaborators ...
Health Care Roundup: Market Talk
Find insight on AstraZeneca, Sino Biopharmaceutical, ConvaTec and more in the latest Market Talks covering the Health Care sector.
Waste Watch: How community colleges spent taxpayer-funded mental health recovery dollars
WLOS News 13 provides local news, weather forecasts, traffic updates, notices of events and items of interest in the community, sports and entertainment programming for Asheville, NC and nearby towns and communities in Western North Carolina and the Upstate of South Carolina, including the counties of Buncombe, Henderson, Rutherford, Haywood, Polk, Transylvania, McDowell, Mitchell, Madison, Yancey, Jackson, Swain, Macon, Graham, Spartanburg, Greenville, Anderson, Union, Pickens, Oconee, Laurens, Greenwood, Abbeville and also Biltmore Forest, Woodfin, Leicester, Black Mountain, Montreat, Arden, Weaverville, Hendersonville, Etowah, Flat Rock, Mills River, Waynesville, Maggie Valley, Canton, Clyde, Franklin, Cullowhee, Sylva, Cherokee, Marion, Old Fort, Forest City, Lake Lure, Bat Cave, Spindale, Spruce Pine, Bakersville, Burnsville, Tryon, Columbus, Marshall, Mars Hill, Brevard, Bryson City, Cashiers, Greer, Landrum, Clemson, Gaffney, and Easley.
Apple Watch and AirPods health features get major new global expansions
Apple has announced noteworthy global expansions for some of its latest health features for Apple Watch and AirPods. Here are the details.
Introducing Shortcuts Playground: Create Apple Shortcuts with Claude Code or Codex
Today, I’m pleased to introduce something I’ve been working on for the past six months: Shortcuts Playground, a plugin for Claude Code and Codex that can create any shortcut for Apple’s Shortcuts app using natural language. With Shortcuts Playground, you can simply prompt Claude Code or Codex with a sentence requesting a shortcut of any
Philip Glass, turning 90, gets tribute from Taylor Mac, Lucinda Childs
Taylor Mac and Lucinda Childs honored Philip Glass and his work with poets during a special performance, one of several celebrations ahead of the composer's upcoming 90th birthday.
Corbus Pharmaceuticals Announces the Appointment of Nishant Saxena as Chief Business Officer and Schedules a Pre-2026 ASCO CRB-701 Data Conference Call
NORWOOD, Mass., May 21, 2026 (GLOBE NEWSWIRE) -- Corbus Pharmaceuticals Holdings, Inc. (Nasdaq: CRBP), a clinical-stage company focused on devel...
Next year’s iPhone Pro models to get radical new design, per leaker
New leaks corroborate a prior report that next year’s iPhone 19 Pro models will feature a radical new design for iPhone’s 20th anniversary.
Apple's 15-Inch M5 MacBook Air Sees Biggest Price Cut Yet at $199 Off
Amazon has sweetened its deal on the 512GB 15-inch M5 MacBook Air today, dropping the price of the notebook down to $1,099.99, from $1,299.00. This is a new record low price on the 15-inch M5 MacBook Air, and it's available in three colors. Note: MacRumors is an affiliate partner with Amazon. When you click a link and make a purchase, we may receive a small payment, which helps us keep the site running.
AI & Science: What Is the Future of Discovery?
Continued progress in artificial intelligence, its expanding usefulness in science, and its contributions to landmark advances suggest that we may have entered a new era of AI for science.The breakthroughs so far—such as predicting the structure of practically every known protein, with profound implications for our understanding of biology, health, and the treatment of disease—are notable not only for what was achieved but also how it was achieved and what that suggests for scientific progress. This special double issue of Dædalus poses the question: What is the future of scientific discovery in this new age of AI? Thirty-three scientists responded. Bringing perspectives from life sciences and medicine, cognitive science and neuroscience, the physical and earth sciences, chemistry and materials science, computer science, mathematics and the social sciences—they draw on their work at the frontier of AI and science. The authors write with an eye to the future, not just the present. They explore what is being achieved and what possibilities lie ahead; examine AI’s limitations and efforts to move forward; and investigate the larger implications of AI-assisted science—on how science is done, the role of the scientist, and the scientific method, as well as the challenges and complexities involved.The authors together exemplify a long-standing bidirectional relationship: AI advancing science, while science advances AI. Where that relationship will take us—a golden age of discovery? New scientist-machine collaborations? Autonomous labs? Discoveries without human understanding?—is a future we are only beginning to imagine, and one we must also shape if the beneficial possibilities are to be realized.Image: UMAP sculptures visualizing three Dædalus volumes on artificial intelligence. © 2026 by Refik Anadol.
iPhone 19 Pro Prototype in Testing Allegedly Has Quad-Curved Display
Apple is testing an iPhone 19 Pro with a display that curves around all four edges of the device, a leaker out of China has claimed. According to Weibo-based Digital Chat Station, the 2027-generation Pro device, currently at the evaluation stage, has a hole-punch cutout in the display for the front-facing camera, but Face ID is completely hidden under the panel.
Bonus 228: The $1.776B Political Question
Every so often a story comes along that is so brazen, so cleanly emblematic of the moment we are living through, that staying quiet about it feels like a kind of complicity unto itself. Monday’s announcement by the Department of Justice that the Acting Attorney General has unilaterally created a $1.776 billion “Anti-Weaponization Fund” to compensate so-called “victims of lawfare” is one of those stories. And the reason I want to write about it here, in a newsletter ostensibly devoted to the Supreme Court and the law and politics surrounding it, is that I’m increasingly worried that we’re asking the wrong institution to save us from one of the most offensive, alarming, and anti-constitutional things we’ve seen from any president in American history. As I explain below the fold, the Anti-Weaponization Fund is not principally a legal problem awaiting a judicial fix. It is a shockingly egregious political abuse—the President suing his own government, purporting to settle with himself, and routing nearly $2 billion from the Treasury to his own supporters as a not-so-subtle (and not-so-formal) reward, if not an incentive, for political violence. And the Constitution’s answer to political abuses of this kind and magnitude is a political remedy, not a legal one. In his majority opinion in NFIB v. Sebelius (the Affordable Care Act case from 2012), Chief Justice Roberts defended the Court’s endorsement of Congress’s power to adopt the individual mandate by noting that it is “not our job to protect the people from the consequences of their political choices.” As much of a judicial supremacist as I am, that sentiment is, for better or worse, an entirely correct (and, in the long term, normatively desirable) institutional assessment. One can believe in substantial judicial power without believing that literally every political dispute in our country can and should be resolved by unelected judges. The real upshot of this latest headline (among so, so many other similar headlines) is that it is past time to reinvigorate impeachment—not because conviction is realistic in this Senate, or even because impeachment itself is feasible in this House, but because forcing every member of Congress to vote on the record whether this brazen, corrosive, and affirmatively dangerous corruption is impeachable is itself a point worth fighting for (and fighting with our friends over). Assuming the courts will save us absolves our political leaders of both responsibility and accountability for allowing this kind of mischief to continue, and it absolves all of us of our responsibility to refuse to tolerate those who would just as quickly shrug their shoulders and move on. For those who aren’t paid subscribers, we’ll be back (no later than) Monday with our continuing coverage of the Supreme Court. For those who are, please read on.
MacBook Pro OLED Display Production Clears Key Hurdle
Apple's first OLED MacBook Pro models have cleared a major manufacturing hurdle, with panel supplier Samsung Display having reportedly achieved yields above 90 percent on its Gen 8.6 OLED production line. According to Korean publication The Elec, some individual process stages are now reaching yields as high as 95 percent, a level that the display industry considers "golden yield" territory for stable mass production.
ACSI: Samsung edges out Apple in cell phone satisfaction, Apple Watch ties at the top
ACSI has published this year’s Telecommunications, Cell Phone, and Smartwatch Study, and Apple’s results are a bit of a mixed bag.
Loma looks to live dangerously in return to the ring
Former Ukrainian pound-for-pound king Vasiliy Lomachenko hasn't officially announced his return to the ring, but the rumors about who will be his comeback fight opponent are already swirling. Gervonta "Tank" Davis was the first name mentioned. That makes sense, since fans of both fighters have ...
AMD Announces Ryzen AI Halo, the Compact DGX Spark and Mac Mini Rival
AMD today released Ryzen AI Halo, a compact AI development computer designed by AMD to serve as a nearly full-stack machine for AI development, inferencing, and generative AI content creation. Ryzen AI Halo is designed to strike a unique balance of price, performance, and capabilities that rival App...
Eddy Cue named 2026 Cannes Lions Entertainment Person of the Year
Eddy Cue has been chosen as this year’s recipient of the Entertainment Person of the Year Award, which will be presented next month at the Cannes Lions festival.
Kansas City has bought more than 4,500 MacBook Neos for its students
The newly “all-Apple district” will replace 30,000 Windows and Chromebook devices across its public schools.
iOS 27's New AI Voice Control Feature Hints at Major Siri Upgrade Coming Soon
Every May, Apple previews new accessibility features coming to devices like the iPhone, iPad, and Mac. The announcement typically occurs a few days before Global Accessibility Awareness Day, and it offers a glimpse into what will be included in the next major releases of Apple's software platforms, such as iOS, iPadOS, and macOS. This year, one of the new capabilities shown off by Apple is natural language support for the Voice Control feature on the iPhone and iPad.
MacBook Ultra could be very good news for MacBook Pro users
Here’s why the rumored new ‘MacBook Ultra’ model could be good news for MacBook Pro users in light of a previous redesign misstep.
Can we harness quantum effects to create a new kind of healthcare?
Experiments hint that quantum mechanisms are vital to the machinery of life. Now researchers are exploring if these effects help to explain the success of an array of puzzling health treatments
Samsung Overtakes Apple for Top Smartphone Customer Satisfaction
Samsung has edged past Apple for the top spot in customer satisfaction for cell phones, according to the American Customer Satisfaction Index's 2026 Telecommunications, Cell Phone, and Smartwatch Study, published this week. Samsung scores 81 in the ACSI's cell phone rankings while Apple posts 80, breaking last year's tie between the two companies for satisfaction leadership.
Interstellar's most-discussed scene is treated as exotic science fiction, but the family-separation problem it dramatises is one of the more actively studied subjects in long-duration mission planning.
The scene that has stayed with most viewers of Christopher Nolan’s Interstellar is not the wave-planet, or the visualised black hole, or the climactic library of moments. It is the one in the middle of the film where Matthew McConaughey’s character, Cooper, watches twenty-three years of his children’s recorded video messages, having lost that span […]
Mace targets Squad Dem with proposed constitutional ban on foreign-born lawmakers
Rep. Nancy Mace proposes expanding the natural-born citizen requirement beyond the presidency to Congress, federal judges and cabinet appointees.
Wellgistics Health and Datavault AI to Form DelivMeds AI via PharmacyChain™ License Expansion and Acquisitions of QOLPOM Biometric Health Data and Drone Logistics IP and Majority of Tollo Health
Formation of DelivMeds AI, Inc. (ticker reserved: NASDAQ:MEDS), with an expected approximate combined asset value of $4 billion, is subject to…...
Observational Comparative Research in Cardiovascular and Brain Health and Disease
Resources for observational comparative research have rapidly expanded to include large, granular healthcare datasets and advanced analytical methods.
WhatsApp working on messages that disappear once you’ve read them
WhatsApp users will soon be able to set disappearing messages to vanish after the recipient has read them. Here are the details.
Bob Brooks, Labor Leader Backed by Top Democrats, Wins Pennsylvania House Primary
Mr. Brooks will face Representative Ryan Mackenzie, a Republican, in the fall. He earned endorsements from across his party, including Senator Bernie Sanders of Vermont and Gov. Josh Shapiro of Pennsylvania.
Plex Tripling Lifetime Plex Pass Price to $750 in July
Media platform Plex today said that it is increasing the price of its Lifetime Plex Pass option to $750, which is a $500 increase from the current $250 price tag. Plex said that the updated price reflects the "real, ongoing value" of the software that it plans to build and maintain.
Future-proof: Why demand for data science is on the rise
As companies gather mountains of information, they need business intelligence analysts working alongside AI to make sense of it all.
How Trump backed off on resuming Iran attacks
In President Donald Trump’s telling, he was an hour away from ordering new strikes on Iran when he abruptly announced on social media Monday that he would allow more time for diplomacy.
Google's First AI Smart Glasses Launching This Fall With iPhone Support
Google today said that its first "intelligent eyewear" product is set to launch this fall. It is teaming up with Samsung and eyewear manufacturers Gentle Monster and Warby Parker to launch new AI audio glasses. The glasses will run Android XR, which is Google's platform for smart glasses and AR/VR headsets. There are cameras, speakers, and microphones in the glasses, but there is no display in the lenses.
CT Department of Correction plans to address healthcare delays
The CT Department of Correction announced a slate of reforms focused on improving the quality of healthcare for people who are incarcerated.
2026 KPAX-Scheels Sports Awards: Big Sky's Averi Larson and Cormack Batt
It's our final day of introducing you to our finalists for this year's KPAX-Scheels Sports Awards, and today, we meet the duo from Big Sky High School in Averi Larsen and Cormack Batt.
France Politics
French President Emmanuel Macron delivers his speech during a conference named "No Money for Terror", on the sidelines of the G7 finance ministers meeting, aimed at cutting off financing of
Plex increasing Lifetime Plex Pass cost to whopping $750
Plex has announced a massive price increase for the Lifetime tier of its Plex Pass plan. Starting in July, Plex...
Fortnite Returns to the App Store Worldwide as Epic Signals 'Final Battle' With Apple
Fortnite is back on the App Store in every country except Australia, Epic Games announced today, as the company declared it is entering the "final battle" of its long-running legal dispute with Apple. Epic said the decision to push Fortnite back onto iOS globally was prompted by Apple's own words to the U.S.
Apple announces return of popular MagSafe iPhone stand and grip
Apple today unveiled a suite of new accessibility features coming with iOS 27, visionOS 27, and more later this year....
Lenovo intros Wildcat Lake laptops as new MacBook Neo alternatives
The new Lenovo Lecoo Air 13, Air 14, and Air 15 have been introduced in China. These are powered by the Intel Wildcat Lake processors, and the laptop line is expected to rival the MacBook Neo in terms of price.
Rangers' MacKenzie Gore Leaves Rockies Game with Left Lat Tightness
The Texas Rangers lost their starter, MacKenzie Gore, to an injury early in Monday's loss to the Colorado Rockies.
Macomb takes first step in the creation of a sports complex
The Macomb City Council approved sending a letter of intent to use STAR Bonds for a sports complex project.
Rangers pitcher MacKenzie Gore leaves game with muscle tightness
Texas Rangers left-handed starting pitcher MacKenzie Gore left Monday night's game at Colorado after one inning because of muscle tightness in his back. Gore’s ailment occurred on the same day that the Rangers placed shortstop Corey Seager on the 10-day injury list because of lower back inflammation. Gore got up gingerly after diving to field a slow roller to the third base side, although it was not immediately clear if that play contributed to his injury.
Baking soda & vinegar volcanoes with Mad Science of Austin & SA
NASA Transfers Management of Lunar Science Instruments
NASA has transferred management of two lunar science instruments to Intuitive Machines, due to the instruments' principal investigators and science team
iOS 27 to add new custom wallpaper feature, more: report
iOS 27 is set to be announced in just three weeks, and a new report today dives into three new...
To help boost Indigenous enrollment in science majors, UMaine Machias is adding Native perspectives
The number of Native Americans enrolling in college has declined by 40% in the last decade and a half. The disparities are particularly noticeable in science and engineering, where Native American students are underrepresented at all higher education levels.
Apple Announces WWDC 2026 Schedule, Sends Media Invites
Apple today provided a schedule for its 2026 Worldwide Developers Conference, which starts on June 8 and ends on June 12. Apple also sent out invites to members of the media who have been invited to attend an in-person keynote viewing at Apple Park. Both the invites and schedule confirm that the keynote will begin at the standard time, 10:00 a.m. Pacific Time or 1:00 p.m Eastern Time.
Apple might replace aluminum with titanium in future iPhones again, per leak
iPhone 17 Pro switched from titanium to an aluminum-based design, but Apple might be exploring an ‘improved’ titanium for future iPhones.
Apple sends invites for WWDC26 keynote, unveils schedule
Apple is officially inviting members of the press to WWDC 2026 today. WWDC will kick off on June 8, with...
Apple Watch Ultra 4 Could Get Redesign and Blood Pressure Monitoring
The Apple Watch Ultra 4 could feature a complete redesign and blood pressure monitoring, according to DigiTimes. Apple will apparently add a new high blood pressure notification feature to the Apple Watch that uses the optical heart-rate sensor on the back of the device to analyze how blood vessels respond to each heartbeat, sending alerts when an abnormal pattern is detected. The feature is said to be under FDA review.
Bridging Systems: How Kentucky is Improving Response to Emerging Health Threats
Learn how Kentucky is integrating public health and health care emergency programs to improve their emergency readiness in this blog.
New iPhone Ultra leaks cover release timing, display breakthrough, more
Leaker Instant Digital has new updates on iPhone Ultra’s production status, release timing, display breakthrough—and a potential hurdle.
Beyond the Game: Exploring Sports, Media, and Culture at Notre Dame
Katherine Walden, assistant teaching professor of American…
New MatterChat Model Helps AI to ‘See’ the Language of Science
From writing emails to generating computer code, much of the artificial intelligence prevalent in our daily lives has succeeded by mastering one domain: text. However, this leaves a major blind spot in the physical sciences, where models depend on the high-resolution, three-dimensional data of the physical world, like the intricate lattice of atoms in a crystal. Delivering on the promise of using AI for science requires teaching these data-driven text models to seamlessly “talk to” physics-based models. Now, a new AI framework from Lawrence Berkeley National Laboratory (Berkeley Lab), called MatterChat, solves this problem by creating a specialized “bridge.” It connects the conversational power of a Large Language Model (LLM) with a physics-based AI that models “interatomic potentials”: the complex physical forces between atoms. The resulting system already significantly outperforms general-purpose AI tools like GPT-4 at predicting material properties, and the team hopes it can accelerate scientific discovery by serving as a robust research partner that provides grounded insights and generates step-by-step instructions for synthesizing novel materials. A paper describing this work was recently published in Nature Machine Intelligence. “Traditional simulations can provide the physical rigor required for materials science, yet their computational cost remains prohibitive for high-throughput screening. Conversely, while LLMs excel at rapid knowledge synthesis, they inherently lack the ‘structural vision’ to interpret materials directly from their underlying atomic coordinates,” said Yingheng Tang, a postdoctoral researcher in Berkeley Lab’s Applied Math and Computational Research Division (AMCR) and lead author on the paper. “MatterChat was built to solve this dilemma, empowering LLMs with a structural ‘vision’ that allows researchers to leverage their full potential for solving complex, real-world materials challenges.” Empowering language models to solve complex challenges in materials science To build MatterChat, the Berkeley Lab team drew inspiration from technologies like Vision Question Answering (VQA) and Text-to-Image (T2I) generation. In these tasks, AI must translate high-level text concepts into visual images, or vice versa. Doing so requires developers to build tools that “bridge” two fundamentally different forms of data. The researchers adapted this concept to the physical sciences. With MatterChat, they created a “bridge model” that successfully connects an LLM’s general knowledge with the deep understanding of the atomic-scale world encoded in scientific interatomic potentials. Until now, researchers using LLMs to solve materials problems usually had to feed them raw data files as if they were just strings of text. It’s like asking an AI to understand a complex 3D engine based only on a parts list: the LLM can read the names, but it can’t “see” how the atoms fit together in space. MatterChat solves this by training a specialized AI bridge model, pre-trained on millions of crystal structures and an LLM, to align the LLM’s representation of the world with the interatomic potential’s representation of the world. The bridge model can translate physical insights into a format the LLM can actually understand. By giving the LLM these “scientific eyes”— a scientific “inductive bias” in the terminology of AI — the Berkeley Lab team has transformed it into a robust research tool capable of providing grounded scientific insights into complex materials challenges, such as predicting thermal stability or analyzing electronic band gaps. “We think of atoms as living in a physical space, but from a machine learning perspective, they are just vectors living in some very non-trivially structured manifold in a high-dimensional Euclidean space; and, of course, the same is true for the sentences and paragraphs that we use to express our ideas about those atoms,” said co-author Michael Mahoney, Berkeley Lab’s Scientific Data Division (SDD) AI Initiative Research Lead. “The bridge model basically gets those two structures to ‘talk with’ each other.” As a proof-of-concept of this general approach, the team trained their bridge model on a dataset curated by pairing nearly 143,000 stable atomic structures from the Materials Project with their corresponding physical properties. This training data was automatically assembled using the Materials Project’s API and deliberately enriched with properties fundamental to microelectronics design — like formation energy and bandgap — allowing MatterChat to learn the complex patterns connecting a material’s atomic blueprint to its functional performance. To validate their model, the researchers benchmarked MatterChat against a suite of other AI systems, from general-purpose LLMs to other specialized scientific AI methods. The results show that MatterChat consistently outperformed its competitors across a range of tasks. The model was more accurate in classifying material types and demonstrated superior precision in predicting numerical properties. For example, it excelled at predicting a material’s bandgap, a property critical for designing new electronics from high-capacity energy storage to next-generation computer chips. “Our design is significantly more efficient because we don’t have to build a massive AI model from the ground up,” said co-author Zhi (Jackie) Yao, a research scientist in Berkeley Lab’s AMCR. “Instead, we take two powerful, pre-trained models — a structural encoder for materials physics and an open-source LLM — and use them off-the-shelf. The only component we actually train is the lightweight ‘bridge model’ that translates between them. It’s the difference between building an entire car factory and simply designing a smart adapter that connects a world-class engine to a world-class navigation system. This approach is not only computationally efficient, but also makes the system modular, so we can easily upgrade components or adapt the bridge for other scientific domains in the future.” Crucially, this modular design highlights exactly how institutions like Berkeley Lab and the Department of Energy are carving out a highly valuable niche in the booming AI landscape. Rather than competing with Silicon Valley tech giants to build ever-larger language models from scratch, the lab is focusing on the specialized connective tissue that makes commercial AI useful for hardcore science. Because the bridge model approach underlying MatterChat is forward-compatible, it is perfectly positioned to leverage these parallel tracks of innovation. As Mahoney pointed out, “We expect that industry will continue to develop improved LLMs, and we expect domain scientists and facilities will continue to generate new data. An important part of scientific machine learning is not simply to solve problems on today’s data, but instead to develop general methods that will be forward-compatible with orders of magnitude more data, whether from scientific domains or from LLMs.” According to Yao, the MatterChat project, which was initially developed and enhanced with funding from a Berkeley Lab Laboratory Directed Research & Development (LDRD) Program, will now expand its capabilities. In a collaboration with Fermilab, MatterChat is already contributing to a U.S. Department of Energy Genesis Mission project — called Accelerating eXtreme Environment Specs-to-Silicon (AXESS) — that aims to speed up the development of next-generation, high-speed, radiation-hardened detectors for challenging particle physics experiments by using advanced 3D integrated circuits (chiplets) and AI-driven data analysis. In addition to the LDRD support, the team also credits supercomputing resources at the National Energy Research Scientific Computing Center (NERSC), located at Berkeley Lab, with MatterChat’s success. “We are incredibly grateful to NERSC; this research simply would not have happened without access to the Perlmutter supercomputer through their AI for Science program,” said Tang. Wenbin Xu, a NERSC postdoctoral fellow at the time, was also a major co-author of the work, as was Benjamin Erichson, a research scientist in Berkeley Lab’s SDD, highlighting the benefits of AMCR-SDD collaboration on AI for science. ### Lawrence Berkeley National Laboratory (Berkeley Lab) is committed to groundbreaking research focused on discovery science and solutions for abundant and reliable energy supplies. The lab’s expertise spans materials, chemistry, physics, biology, earth and environmental science, mathematics, and computing. Researchers from around the world rely on the lab’s world-class scientific facilities for their own pioneering research. Founded in 1931 on the belief that the biggest problems are best addressed by teams, Berkeley Lab and its scientists have been recognized with 17 Nobel Prizes. Berkeley Lab is a multiprogram national laboratory managed by the University of California for the U.S. Department of Energy’s Office of Science. DOE’s Office of Science is the single largest supporter of basic research in the physical sciences in the United States, and is working to address some of the most pressing challenges of our time. For more information, please visit energy.gov/science.
Apple Watch Ultra 4 getting two major new upgrades, per report
A new report from Digitimes highlights two major upgrades coming with Apple Watch Ultra 4 when it launches this fall.
Sony's 10th Anniversary 'Collexion' Over-Ear Headphones Leaked
Sony's latest noise-canceling headphones have been leaked. Images of the 10th anniversary models, called 1000X "The Collexion" Edition, were shared online today by OnLeaks. They're expected to launch tomorrow, coming just a year after the company's WH-1000XM6 series. From what we can tell based on the leaked materials, the changes are largely design-based.
The asteroid that wiped out the dinosaurs may have triggered a global fungal bloom
The asteroid that smacked into our planet about 66 million years ago at the Cretaceous-Paleogene (K/Pg) boundary may have been bad news for dinosaurs, but it was good news for fungi. According to new ...
Apple's faulty chips are big business for the company
Apple has for years been using a procedure known as chip binning to reuse faulty chips in other models of...
Ben Butler jumps into arena against Darren Soto in CD 9
The agricultural leader boasts endorsements from Kat Cammack and Greg Steube.
Game #46 GameThread: Jays @ Tigers
Game Three with the Tigers and then the Jays head off for four games in New York against the Yankees. And Adam Macko is up with the team. He told reporters that he rushed around to buy ‘collared shirts’ to wear on the team bus, saying that he only had hoodies. It seems that I’ve […]
Report: Apple to upgrade Genmoji in iOS 27 with new automatic suggestions
According to the Power On newsletter from Mark Gurman, Apple is planning an interesting new Genmoji feature in iOS 27...
Kids’ mental health - time to close the gap: Marissa Kiefer
Mental and behavioral health challenges among young people are not rare -- they’re part of life for many families. But at UH Rainbow Babies & Children’s, we’re dedicated to trying new approaches, writes guest columnist Marissa Kiefer, president of University Hospitals' Rainbow Babies & Children’s and MacDonald Women’s hospitals.
First Public macOS Kernel Exploit on Apple M5 Prepared Using Mythos Preview in Five Days
Apple's M5 silicon has reportedly been exploited for the first time in a public macOS kernel memory corruption attack, successfully bypassing the company's notable hardware-level memory protection.
Sunday Preview – Mighty war machines in the Age of Darkness
Tracked reinforcements arrive for the Legiones Astartes in next week’s pre-orders.
Scientists discover why some cancers survive chemotherapy
Scientists have uncovered a surprising new trick used by one of cancer’s most notorious proteins. MYC, already infamous for fueling runaway tumor growth, also appears to help cancer cells survive by repairing their damaged DNA — including damage caused by chemotherapy and radiation. Researchers found that MYC can rush directly to broken DNA and recruit repair machinery, effectively helping tumors recover from treatments meant to destroy them.
Winter Sports Wrap: See Belmont’s League All-Stars
In Mackenzie Clarke’s own words, she felt FOMO (Fear of Missing Out). After missing her sophomore season of ice hockey to focus on year-round field hockey in the most important year for her college recruiting, she yearned to return to her first sport at the high school level. Two years later, she’s graduating as the lone Belmont High School All-Scholastic honoree across all Marauders winter athletes. “It’s always been a part of me,” Clarke said. “I started to miss it, and a bunch of people who I played field hockey with were on the team that year.” The senior forward
This rumored MacBook Pro upgrade has me excited, and it has nothing to do with OLED
Later this year, Apple is set to debut its first MacBook Pro redesign since 2021. With that redesign, we’re expecting...
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Chartbook 449: Voldemort on Threadneedle street. The Bank of England and the "haunted house" of English politics.
Imagine the scene: In some Harry Potter version of 21st-century London, a group of deathless UK Treasury officials gathered from across the last century huddle over warm pints and glasses of Chardonnay. Around the table there are officials from the 1920s, the 1930s, the 1970s, 2022 and today. Inevitably, in May 2026, the subject of conversation is the disintegration of the current Labour government. Despite its huge majority in parliament, it has been reduced to tatters by catastrophic local election result. These exposed the fact that rather than having a government with a clear popular majority, the UK is like most other modern societies divided into 5 segments each of which commands between 26 and 16 percent of the vote. Perhaps unsurprisingly, the leadership at Nos 10 and 11 Downing Street - where the Prime Minister and the Chancellor (Treasury Secretary) work - seem paralyzed. They are caught between mounting discontent over unfairness and the cost of living, and tough fiscal strictures that push them into making unpopular spending decisions. In the London pub, the Treasury officials from across the ages, can barely hide their satisfaction at the latest display of democratic politics caught in the vice-grip of financial logic. “Remember the mur d’argent and the banker’s ramp?” “Just like yesterday!” There are smirks around the table. Then the representative of 2026 pipes up: “One thing you have to say about the current lot (referring to the latest hapless Labour government), you don’t have to teach them about the bond market!” There is a murmur of ascent from the Treasury Mandarins. The trauma of the fiscal crisis of September-October 2022 sits deep. Back then, in the final stages of Tory decay, a ‘mini budget’ that challenged fiscal orthodoxy led to a brief but fierce panic in one of the oldest government bond markets in the world (aka gilt market). Now all you have to do is to mention the “bond market” to hush debate. [ Paul Mason@paulmasonnews In the name of public service, and as ex-economics editor of BBC Newsnight, I offer to do a zoom call, tonight, with any Labour MP who wants to understand why bond markets do not "fall into line" with governments. 1/ 3:57 PM · May 12, 2026 · 466K Views 224 Replies · 674 Reposts · 3.93K Likes ](https://x.com/paulmasonnews/status/2054229532404519082?s=20) “And the funny thing is”, the young man in the huddle continues, “they don’t even want to talk about … ”. There is a sudden hush. Significant looks are exchanged around the table. About? One of the senior figures puts down his glass with a decisive “clink”. He-Who-Must-Not-Be-Named has entered their thoughts. Meanwhile, a few miles away in a grubby pub in Bloomsbury, two conspirators from the camp of Critical Macrofinance huddle over cans of low-alcohol IPA. They look at each other and blurt out loud: “The Bank!” “Everyone in the bloody Labour party is talking about the bond market. But why aren’t they even mentioning … the Bank of England!?” “Why is no one talking about Voldemort?” In Paul Mason’s blogpost, after much chest-thumping about basic fiscal logic, the basic point about the Bank of England is buried in the fine print at #3 in his list of suggestions as to what a radical Labour government might actually be able to do! [ Conflict & Democracy Down with the bond market! Down with gravity! It may seem unfair to focus on Labour MP Paula Barker for her off-the-cuff assertion that the bond market would have to “fall in line” with Andy Burnham, should he replace Keir Starmer as prime minister. But Burnham himself told the New Statesman that Labour had to “get beyond this thing of being in hock to the bond markets… Read more 2 days ago · 100 likes · 3 comments · Paul Mason ](https://htsf.substack.com/p/down-with-the-bond-market-down-with?utm_source=substack&utm_campaign=post_embed&utm_medium=web) Back in Bloomsbury they shake their heads and ask: “Didn’t we learn anything from the Eurozone crisis?” Meanwhile, as if summoned to the conversation by some higher force, the “pink pages” announce: “The days of ultra-cheap government borrowing have come to an end” and Martin “Whizzard” Wolf publishes the graph of the season Look at the UK in 2026, perilously positioned on the upper edge of the pack. No wonder no one in London needs any lessons about the “bond market”. But, look again. Imagine how they feel in Rome. What is London’s nightmare in 2026? The nightmare is that you end up like Italy in the early 2010s during the Eurozone crisis. Once comfortably situated in the middle of the pack, watching with horror as your ten-year yields explode to 7 percent and “spreads” become a national nightmare. One of the largest economies in Europe, a founding member of the euro, stigmatized. But the message of the Italian experience is ambiguous. After all, the stigma didn’t last. In 2026, Italy borrows at rates lower not only than the UK but the US. The US, which, as everyone knows, enjoys the “exorbitant privilege” of being the issuer of reserve, safe asets. What kind of magic is this? How did Italy, in the space of fifteen years, go from being good, to bad and back again? Which brings us back to our dissident friends in their Bloombury boozer and their memories of the Eurozone crisis. Italy never was Britain - with its ongoing fiscal deficits. Without interest payments, on primary balance, from 2000 to 2020 Italy ran a tight fiscal ship. Even in 2008 it barely went into deficit and when it was being put on the rack in the early 20210s its primary surplus matched that of austere Germany. So, what happened? How did it end up stigmatized? Of course Italian politics didn’t help. Berlusconi was at the helm and he had legal issues. But amongst friends in the Bloomsbury pub, Berlusconi is a sideshow, the name we whisper to each other is “Trichet”. From 2004 to 2011 the ECB was headed by Jean-Claude Trichet, ex of the French Treasury, more German than the Germans. After 2009 as the news of the Greek fiscal disaster broke, the European bond markets wento into panic mode and Trichet began a brutal game of cat and mouse. Between 2009 and 2011, Trichet intervened in the bond market to help, only when he thought he had compliance with austerity. When he thought they were uncooperative, he withdrew. In the summer of 2011, he even made direct suggestions to his Italian counterparts in Rome, as to how Italy should be governed. It was this cat and mouse game that drove the bond markets crazy and exposed Italy to a violent squeeze. When Mario Draghi took over the ECB at the end of 2011 and declared “whatever it takes”, the pressure on Italy, gradually eased. It is that starring role that has made Draghi into the towering figure in European politics that he remains today. So now you see why voices in London hush when it comes to the Bank of England. “The bond market” isn’t an irresistible objective force like the weather or an avalanche. It can appear like that. But that depends on the way it is being handled, or not handled by the central bank. Which is why the silence about the Bank of England in London right now is so significant. If you think this all sounds a bit fishy, coming from a left-liberal Keynesian like myself, well, let me introduce you to Robin Brooks, who, to put it mildly, plays on a different quidditch team to me. Here, from the position of a fiscal hawk is Robin’s celebratory account of the Bank of England’s role since 2022; In October 2022, at the height of the bond market blow-up in the UK, something incredible happened. Governor Andrew Bailey told British pension funds the Bank of England would end its support program for the country’s fragile gilt market, drawing a line under how much help the central bank was willing to give to exposed pension funds and - implicitly - the government. By the end of that week, Kwasi Kwarteng - the finance minister - had resigned. Prime Minister Liz Truss would soon follow. This episode is so incredible because it contrasts with what happened in the Euro zone earlier that year. Bond markets in Spain and Italy were under pressure amid high inflation and rising interest rates. In the middle of this, Mario Draghi - Italy’s Prime Minister - resigned, compounding pressure on bond markets of high-debt countries on the Euro periphery. Unlike the Bank of England, the ECB caved. It bought Italian and Spanish government bonds in an effort to cap yields and introduced a new tool that signaled to markets it might do such caps more frequently going forward. Faced with pressure on bond markets, the ECB capitulated to political pressure from high-debt countries like Italy and Spain. The Bank of England stood its ground and toppled the Truss government. This kind of thing has long-lasting consequences. It means markets price a higher probability of yield caps in the Euro zone, which keeps Italian and Spanish yields artificially low, while markets feel free to push up UK yields without fear of central bank intervention. As I flagged in yesterday’s post, this means you really can’t compare UK yields to those of other high-debt countries. The UK looks worse, but only because its central bank isn’t interfering with markets. There’s more to this than just that 2022 episode. The Bank of England has also been much more aggressive in its quantitative tightening (QT) than other central banks. If one motivation for quantitative easing (QE) is to lower bond yields - especially longer-dated ones - then it stands to reason QT pushes yields up. The left chart above shows a four-quarter moving average of UK government debt issuance (black line) in percent of GDP and which sectors absorb this issuance, including the Bank of England (blue bars). The right chart above compares the Bank of England’s accumulation or run-off of government bonds (blue line) with that of other central banks, where this blue line is the same as the blue bars in the left chart. The Bank of England was quicker and more aggressive than other central banks in downsizing its bond holdings, so UK yields will have risen more than elsewhere also for this reason, not just because of Governor Andrew Bailey’s remarks in October 2022. Back in October 2025, after a conversation in New York with friends in British politics, my sense of dysphoria was such that I raised the issue of the Bank of England openly in the FT Since 2008, the UK has slid into a deep economic and political predicament. Growth has stagnated to a degree far worse even than in the 1970s. The Tory leadership’s wager on the Brexit referendum spectacularly backfired, leaving the UK isolated from Europe and at the mercy of its special relationship with the US, many of whose political class regard the UK as a basket case. After years of austerity, the Labour party lurched to the left and then back to the centre. The Tory party has been eclipsed by the populist nationalism of Reform. Any British government should be worrying first and foremost about how to restart growth. Instead, Keir Starmer is beset by shades of the gilt market panic triggered by the Liz Truss government in 2022. The debt level is higher than in recent years, but there is no cause for panic. UK debt is at far from critical levels and of long duration. Whether you want to “take back control” or launch progressive economic policy, a democracy dogged by fear of bond market vigilantes is unhealthy. In a country that is a monetary sovereign, this climate points to one thing: a disconnect between the government and the central bank. Since 1997, the independence of the Bank of England has become a sacred cow. But independence is what you make of it. And in the wake of the gilt market crisis of September 2022, relations between the Bank of England and the UK government need a reset. In normal times, there is no doubt that an inflation-targeting independent central bank can serve a country well. But since 2008, the UK and other advanced economies have not had the luxury of such simple problems. To their credit, central bankers around the world have not stood on orthodoxy. After 2008, the US Federal Reserve rescued the global banking system and, through quantitative easing, it stabilised the Treasury market in the face of huge deficits. In Europe, things were trickier. Both the Bank of England under Mervyn King and Jean-Claude Trichet’s European Central Bank played cat and mouse with national governments. This was a high stakes wager that between 2010 and 2012 escalated bond market tension and triggered a disastrous turn to austerity. Shaken by the impact of those shocks, their successors, Mark Carney and Mario Draghi adopted a more protective stance (assuming you were not the government of Greece). Recall that Draghi’s legendary slogan, “Whatever it takes”, was uttered to face down the City of London’s bond vigilantes. In 2015, Draghi launched QE — financial repression by another name. In 2016, Carney used the authority of the Bank of England to stabilise markets following the vote for Brexit, an exemplary demonstration of how central banks can underpin democratic choice, even when those choices are wrong headed. All these were independent central bankers steeped in the best practice of the 1990s, who recognised that historic crises demanded radical action. It was the price surge of 2021-2023 that poisoned the atmosphere. Though the shock came mainly from the supply side, central banks ended up in the dock. Nowhere more so than in the UK. The Bank of England reacted with aggressive normalisation. Faced with a cost of living crisis, the governor called for workers to accept real wage cuts. In early 2022, as gas prices were at record levels and Russia’s army was poised to invade Ukraine, the Bank adopted a stringent programme of quantitative tightening, elevating interest rates. When the Truss government got itself in trouble, the Bank took almost a week to come to the rescue. Rather than enacting a charade of normality, it is time to recognise that in 2025 the UK faces a period of historic transition. To meet this challenge, what is needed is a new concordat with the Bank. This should not ignore inflationary pressures or the long-run trajectory of debt, but should affirm the priority of reviving investment-led growth. One could follow Donald Trump in demanding interest rate cuts. The Bank could shadow the ECB in its commitment to capping Eurozone yields. But the top priority should be to lay the ghost of September 2022. The Bank’s slowing of QT last month was a concession. An immediate and complete end would send the right signal. Such a concordat will not by itself restore sanity to politics, solve the housing problem or rebuild the NHS. But it would help to lift the fear of bond market crisis, which is paralysing the effort by democratic politicians to answer the fundamental questions facing the nation. Now, that call for a new concordat between government and Bank of Englands seems more urgent than ever. The problem is that in October 2025, Starmer still had some authority. Today the government is in tatters. And when you are the “under the harrow” - to echo a phrase of Montagu Norman’s from the 1920s - it is the worst possible time to consider institutional change. To make general arguments at a time of crisis can only seem like special pleading rather than a general argument for long-term change. The same, unfortunately, is also true for the other basic institutional reform that Britain urgently needs i.e. the abolition of the out-dated first past the post electoral system and its replacement by a moderated form of proportional representation. And thirdly - whilst we are saying the quiet parts out loud - Britain needs to reopen the question of EU membership. What the local election results of 2026 show is that this remains a key issue. And what they also show is that there is a clear majority that would favor a return. Until these basic features of Britain’s political economy are addressed the country will carry on its politics as though in a haunted house, governed by governments that lack actual majorities, conjuring up false constraints whilst ignoring the real ones. This one is for DG and MI. I love writing the newsletter. If you enjoy it too and fancy buying me a coffee once a month, you know what to do. Click below! Subscribe