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Bangladesh fights world's worst measles outbreak as vaccination gaps fuel spread
Bangladesh, which once came close to eliminating measles, is facing its worst outbreak on record, with 999 suspected and confirmed measles-related deaths reported since March as hospitals struggle with overcrowding, shortages and a continuing influx of sick children.
Baton Rouge General's Health Tip of the Week: Another sugar substitute raises heart concerns
Sponsored by Baton Rouge General Cutting back on sugar? Take a peek at the ingredient label before reaching for a sugar-free treat. Recent research has raised questions about xylitol, a sugar alcohol found in products like gum, candy and baked goods. Higher blood levels of xylitol were linked to a greater risk of heart attack […]
Signs of US-style polarisation in Britons’ trust in science
Sense of shared identity makes Greens’ faith in scientists stronger than Reform voters’, study finds
Anthropic researcher quit, says AI labs are 'gambling with our lives'
An Anthropic researcher who once worked at OpenAI just quit. He's the latest insider warning that the AI race has become dangerously reckless.
Study Findings Conflict with Body of Science Linking Pesticides to Attention Deficits and Autism - Beyond Pesticides Daily News Blog
A recent study finds no connection between levels of urinary biomarkers of organophosphates and autism-related traits, conflicting with a wide body of research.
Cleveland Clinic, RIKEN and IBM Team Advance to Finals for 2026 ACM Gordon Bell Prize
Joint research team modeled a 12,635-atom protein, the largest-known to be simulated using quantum computers. Breakthrough was achieved through quantum and classical methods working together, expanding quantum-centric supercomputing’s potential in life sciences research.
US Research Cuts Drive Scientists to Germany
US-based researchers are seeking academic asylum in Germany following the Trump administration’s funding cuts—a loss to American science.
Why a shorter eating window may not mean better metabolic health
In a nationally representative cross-sectional study of 16,973 Korean adults, researchers identified three distinct eating patterns based on the timing and distribution of daily energy intake. Eating later within a shorter daily window was associated with higher odds of metabolic syndrome, elevated blood pressure, triglycerides, and fasting glucose, while frequent grazing showed a mixed metabolic profile.
Astrocyte changes may explain how stress affects mental health
A new study led by UCLA Health researchers has identified a specific type of brain cell and a tiny structure on its surface that changes when the body is under stress, which may help explain why stress can lead to anxiety and depression.
Menopause documented far less often in electronic health records
Menopause is frequently missing from women's electronic health records, according to a University of Colorado Anschutz study of nearly 396,000 women participating in the National Institutes of Health's All of Us Research Program.
Archimedes Science Award 2026
Detlef Günther, Swiss Federal Institute of Technology (ETH) Zurich, Switzerland, honored
A (temporary) win for science and sanity
Congress rejects rule that would give Trump control over all research and academic grants—for now
UC Berkeley Welcomes QuantrolOx to its Quantum Innovation Corridor
Quantum researchers and campus leaders heralded the arrival of QuantrolOx at UC Berkeley’s Roger Herst Quantum Nexus. The occasion marks the first U.S. office for QuantrolOx, establishing a foothold
A beginner’s guide to open science
Open science may seem impenetrable for early career researchers. Sarahanne Field explains what it is and how to get started
“Parachute science” is failing the tropics, home to more than 80% of insect species
Insects quietly hold much of the natural world together, yet conservation efforts are overlooking the tropical regions where more than 80 percent of insect species live. Monash University researchers have developed a global framework to close this gap by combining scientific studies with museum collections, local expertise, citizen science, social media records, and new technologies.
A study links prenatal acetaminophen with reproductive changes in girls. Doctors say it remains safe to use when needed
A new study found that some girls born to mothers who took acetaminophen during pregnancy developed reproductive organ changes that could affect fertility later in life. It’s a finding the study authors say should drive future research but shouldn’t yet change how certain symptoms are treated during pregnancy.
Faculty Focus: Chris Erickson, College of Business
Chris Erickson has spent 40 years at NMSU as an economics professor, researcher and mentor. Erickson, a professor in the Department of Economics, Applied Statistics and International Business in...
UNC Charlotte's Truman Lab awarded new $2.1 million grant from the National Institutes of Health
UNC Charlotte’s Truman Lab has secured a new $2.1 million grant from the National Institutes of Health to advance fundamental research on how cells maintain protein health, a process central to diseases ranging from cancer to neurodegenerative disorders. The five-year Maximizing Investigators’ Research Award from the National Institute of General Medical Sciences will support the […]
UNC Charlotte's Truman Lab awarded new $2.1 million grant from the National Institutes of Health
UNC Charlotte’s Truman Lab has secured a new $2.1 million grant from the National Institutes of Health to advance fundamental research on how cells maintain protein health, a process central to diseases ranging from cancer to neurodegenerative disorders. The five-year Maximizing Investigators’ Research Award from the National Institute of General Medical Sciences will support the […]
Congratulations to Our New CRUK Funded Researchers - Cancer Research UK Science and Innovation
Congratulations to Our New CRUK Funded Researchers - Cancer Research UK Science and Innovation / Amy Case, Andy Scarsbrook, cancer, Cancer Research UK Science
Game Awards Host Geoff Keighley And PlayStation Architect Mark Cerny Will Start Giving $2 Million To Young Game Designers Each Year
The Nova Games Foundation is a new philanthropic initiative aimed at supporting the next generation of game makers
Mapping the Global Health Landscape: Analysis of Fourteen International Organizations
The global health architecture includes a number of diverse international organizations with different mandates, governance models, financing structures, and operational approaches. This KFF resource looks across a range of variables to provide a descriptive mapping of 14 key global health and related international institutions. It is intended to inform discussions about synergies and coordination, duplication, comparative advantage, shared challenges, and architectural reform.
Exclusive: Two of gaming’s biggest names are making a big investment in gaming’s future
The first thing to know about the Nova Games Foundation is that it isn’t about The Game Awards. And it’s not about PlayStation. The ambitious new grant program is the brainchild of Geoff Keighley and Mark Cerny. Keighley is the host of The Game Awards, Summer Game Fest and Opening Night Live. Cerny is a game designer of some 45 years and the lead architect for the PlayStation 4 and 5. But this new thing, which they’re revealing through Game File, isn’t about their day jobs. It’s an unaffiliated, standalone philanthropic project. It’s a bet on the artistic future of video games and a way, they tell me, to give back. “I’m nearing the end of my career,” Cerny recently told me over email. “I’m not done yet, but paying it forward—in the best way possible—is very much on my mind these days,” The Nova Games Foundation is a university-affiliated fellowship program, intended to offer six-figure grants to 20 young game designers each year, potentially for decades to come. It will offer no-strings-attached funding along with mentorship from games industry leaders, a combination intended to aid the development of groundbreaking new games, Cerny and Keighley told me. Nova will begin accepting applications in December, from class of 2026 and 2027 students from 13 affiliated gaming programs at universities in eight countries. The schools working with Nova include the New York University and the University of Southern California in the U.S., along with Abertay University in Scotland, Cnam-Enjmin in France, TH Köln in Germany, and the Royal Melbourne Institute of Technology in Australia, Cerny and Keighley said. The plan: $100,000 per recipient, with about a quarter of Nova fellows eligible for up to $500,000 more for projects that are shaping up particularly well. Payments will be delivered based on development milestones, and recipients will own their games. Nova will help promote the work, and developers will be free to pursue the publishers and platforms of their choice. Nova can help introduce fellows to publishers, but won’t take a cut. “I’ve always wanted to give back, but given my role in the industry, I’ve never felt it appropriate to commercially invest in games,” Keighley told Game File. “I’ve never owned stock in a game company or taken a financial stake in a game. Nova is philanthropy: we aren’t taking equity or looking to recoup the grants. The return we’re hoping for is creative—helping new voices make games and find their footing. “Mark and I have each made multi-million-dollar donations to establish the foundation, and we intend to keep contributing. We hope others will join us.” Cerny and Keighley have already hired an executive director, John Maconga, and a head of grants, recent Game Developers Conference director Ashley Corrigan, to help launch the effort. They’re working to recruit game industry leaders to join the effort. Keighley says “dozens of leading game directors have already expressed interest in contributing their time.” To name one, they’ve already gotten Josef Fares, lead designer from It Takes Two and Spit Fiction studio Hazelight on board with a donation and pledge to help out. “I’m proud to support Nova because it gives the next generation of creators the freedom to explore their creativity and hopefully bring their unique visions to life,” Fares told Game File. A plan forged from a friendship Keighley and Cerny have known each other a long time. It’s been so long, Cerny isn’t even sure exactly when they met. “We travel in much the same circles and I’m sure first intersected in the 90s or early 2000s,“ Cerny said. Keighley thinks it might have been during his stint writing a column about the mid-’90s console 3DO for a gaming magazine while Cerny was working on games with Crystal Dynamics or on Way of the Warrior with Naughty Dog. They became genuine friends about a 10 years ago, Keighley said, as they bonded over a shared love of games and a hope to improve the industry. “About a decade ago, we started having dinner a few times a year in LA,” Keighley said. “Just to catch up on life and the industry. Those conversations continued over Zoom during COVID. Nova grew out of that friendship and a question we kept coming back to: ‘What could we do to help the next generation of game directors get started?’” Keighley credits Cerny with the idea to figure out a way to put their money and time back into the industry. At one of those dinners, Keighley proposed the idea of a fellowship program. He’d recalled applying for a Rhodes Scholarship when he was younger. “Spoiler: I didn’t get it,” he said. He’d admired the MacArthur Foundation’s so-called “genius grants.” He liked these kinds of programs that recognized people’s talents and gave them the financial boost and the freedom to realize their potential. With Cerny, he had pondered what a game industry version of that could be. Keighley liked the idea of centering the fellowship on students, drawing inspiration from the accomplishments of Jenova Chen, the USC game design graduate who went on to lead the creation of gently moving, ambitious games such as Flower and Journey. Keighley also thought it could be useful to help promising graduates bridge the transition from student to professional. “Joining an established studio isn’t always possible—especially in today’s market—and even then, it isn’t the right path for everyone,” Keighley said. A fellowship, he realized, could give “graduates the time, resources and guidance to pursue a game of their own and not worry about the commercial viability.” As the idea took shape, Cerny also saw an opportunity to enable more games of a certain type: “The target with the grants is games as an artistic medium,” Cerny told me. “We like to say games with ‘artistic, literary and societal value.’” He added: “I’m a pretty big gamer myself, though I tend to gravitate towards the smaller and more unique or artistic titles, games like Neva, Abzu, Gorogoa, Stray or Outer Wilds. I was just playing and Roger on a flight to Japan, and was getting misty eyed to a degree that I was concerned that a flight attendant would ask me if I was OK. “So one fun benefit here is the games that will come out of the Nova Games Foundation – I can’t wait to play them myself.” Cerny believes it will also be useful for Nova fellows to hone their craft and team leadership skills. “We are looking for the next generation of visionaries,” he said. “The trick is that they will also need to have the executive function necessary to drive a small project to completion.” Game File is a reader-supported publication. To receive new posts and support my reporting, please consider becoming a free or paid subscriber. Subscribe Going big with this Keighley and Cerny may have started Nova and may be the ones primarily backing it right now, but they’re dreaming of something that goes beyond them. “Mark and I may have helped get it started, but one of our measures of success is that Nova grows into something the entire games industry feels a sense of ownership in,” Keighley said. “Our ambition is to build a lasting endowment supported by people and companies across the industry, and an equally broad community of creators willing to give their time and experience to the next generation.” The industry has a lot of knowledge that it can pass to the next generation, Keighley said: “Nova can hopefully become a way to connect that generosity with talented young creators at the moment when it can make the biggest difference.” Cerny, who told me he believes Nova can mature “over the next 10 or 20 years,” sees an opportunity to give generations of game makers momentum. “The industry has changed immeasurably since I started in games in 1982,” he said. “These graduates have talent, training and tools that outclass what we had back in the day by an astonishing amount. But they face a tough road ahead getting traction in the industry, and many could benefit from our support. We want to be there to give it to them.” “There’s a personal side to this, too,” Keighley said. “I don’t have children, and I’ve spent a lot of time thinking about what I can do for future generations. Games have been my entire career. I’ve been incredibly fortunate, and helping someone else build a life in this industry feels like a meaningful way to give back.” Cerny’s oeuvre dates back to Marble Madness and Sonic the Hedgehog 2. He has stood on stage multiple times to reveal the future of PlayStation hardware. He’s been an executive producer for a string of modern PlayStation classics such as The Last Guardian and Marvel’s Spider-Man. Nevertheless, of Nova, he said, “It’s certainly not like anything I’ve done before.” Nova Foundation applications will be due in December and the first wave of fellows will be announced in March 2027. A full list of participating universities and steps students and recent graduates can take to apply to become a Nova Fellow is forthcoming.
B2B Marketing Leaders Struggle to Prove Business Impact: 10Fold
10Fold research finds B2B leaders measure more than ever but struggle to connect metrics to revenue. See the communications ROI reset.
Mysterious elk deaths in Nevada could offer clues about health of herds across the West
An unusual pattern of springtime elk deaths for more than a decade in northern Nevada has scientists searching for answers. What they find could shed light on broader questions about wildlife health across the West.
Mysterious elk deaths in Nevada could offer clues about health of herds across the West
An unusual pattern of springtime elk deaths for more than a decade in northern Nevada has scientists searching for answers. What they find could shed light on broader questions about wildlife health across the West.
This cosmic particle was never meant to reach Earth. Now, scientists think they finally know why it did
In 2022, researchers detected a very odd photon from an enormous gamma ray burst that should have been destroyed on its way to Earth
Louisiana’s marine research collaboration becomes a political battleground
A select group of Louisiana higher ed leaders are discussing what to do with the state's marine research consortium
Meet Rachel Chen, the 18-year-old Los Angeles student who expanded a 1997 quantum-math idea to describe entire particle systems with simple diagrams; she won $100,000
At just 18, Rachel Chen has taken a decades-old mathematical idea and expanded it into a visual framework for understanding complex quantum systems, earning her a $100,000 award in the 2026 Regeneron Science Talent Search.
Endometriosis may increase type 2 diabetes risk
Researchers found that some women with endometriosis may have increased risk of developing type 2 diabetes.
Astronaut Health, Lunar and Earth Photography Fill Crew’s Research Schedule
Exploring astronaut health and photographing the Moon and Earth topped the research schedule for the Expedition 75 crew aboard the International Space Station on Tuesday. The orbital residents also kept up life support maintenance following the departure of cargo spacecraft the day before.
More evidence that mass shootings are suicidal acts
New research finds national peaks for suicides, gun rampages take place within days of each other in summer.
Florida State's Mike Norvell getting booed is nasty business
Things aren’t going well right now for Florida State football head coach Mike Norvell . Not only did his team lose a game on Monday to SMU, but Norvell is also getting booed by fans . “They just played a video of Mike Norvell announcing that the Marching Chiefs would be in the Macy’s Thanksgiving parade. The crowd booed Norvell. (It did cheer for […] The post Florida State's Mike Norvell getting booed is nasty business appeared first on ClutchPoints.
Florida State's Mike Norvell getting booed is nasty business
Things aren’t going well right now for Florida State football head coach Mike Norvell . Not only did his team lose a game on Monday to SMU, but Norvell is also getting booed by fans . “They just played a video of Mike Norvell announcing that the Marching Chiefs would be in the Macy’s Thanksgiving parade. The crowd booed Norvell. (It did cheer for […] The post Florida State's Mike Norvell getting booed is nasty business appeared first on ClutchPoints.
Scientists Are Still Trying To Understand How the Moon Formed
The Earth and the Moon have nearly identical isotopic compositions, and the Giant Impact Hypothesis strives to explain this. New research into the ancient impact shows how the temperature of both worlds, and how it affects the strength of the materials involved in the collision, shaped the outcome, including the isotopic compositions.
From science to screen time: 4 key takeaways from the latest PISA results
Amid reading declines that included a 14-point drop for the U.S., researchers are looking at the role digital learning and AI may have played.
Stand Up for Science Demands Congress Stop Transfer of National Institutes of Health Research Funds to
New petition urges Congress to stop an interagency agreement that would allow health research money to fund War Department’s unspecified priorities.
Stand Up for Science Demands Congress Stop Transfer of National Institutes of Health Research Funds to
New petition urges Congress to stop an interagency agreement that would allow health research money to fund War Department’s unspecified priorities.
Harvard, MIT scholars head north as Carney offers millions
Canada is investing $362 million to lure 64 top global scholars, including dozens from Harvard, MIT and other elite U.S. universities, to advance research in health and artificial intelligence.
In 2018, scientists seeded clouds over China's Muz Taw Glacier to make snow; the brighter surface was followed by 14% to 17% less ice loss in a preliminary experiment
Researchers in China have tried to make artificial snow over China’s Muz Taw Glacier to slow its melting. The experiment conducted in 2018 involved seeding clouds with silver iodide, which helped trigger snowfall over the glacier.
Are rich people really worse behaved? Here’s the science
Who’s more likely to steal sweets from a child? According to science, it’s the rich. A study seemingly confirming our suspicions about the moral behaviour of the wealthy was one of the winners of the 2026 Ig Nobel prizes, which honour research that makes you laugh and then think. Science editor Ian Sample tells Madeleine Finlay what the researchers think could be behind the phenomenon, and they explore some of the other awards, including one for a surprising quality we look for in our friends and another for a biomechanical definition of kissing
Scientists Discover the 7 Stages a Meteoroid Goes Through Before Hitting Earth
An analysis of 75 meteorite falls identified seven distinct processes that occur as space rocks melt, break apart, and slow down before reaching the ground. A space rock entering Earth’s atmosphere does far more than simply “burn up.” By examining 75 meteorite falls recorded in videos and photographs, researchers identified seven distinct stages that shape
Liverpool’s hunt for a new sporting director: Julian Ward and the standout internal options
FSG president Mike Gordon is leading the search for Richard Hughes' replacement, with both internal and external candidates being considered
Humann Names Dr. Harold Schmitz Science Advisory Chair and Announces Nutrition Research Partnership with the UC Davis Innovation Institute for Food & Health
/PRNewswire/ -- Humann, the Austin-based cardiovascular health supplement company, continued its legacy of engaging with leading academic institutions by...
New-to-science Amazon frog stands out for its slow ‘lazy’ song
Scientists recently described a new species of a tiny brown frog found in the Amazonian floodplain forests of Ecuador and northwestern Brazil. It looks nearly identical to related species but its slow, widely spaced out call sets it apart, researchers note in a study. “I’ve had to get into arguments because people said the frog […]
Proposed Changes to Head Start Undermine Its Role in Promoting Child Nutrition and Healthy Eating - Food Research & Action Center
Published September 8, 2026 For more than 60 years, Head Start has supported young children during their most important phase of growth and development. For families with limited resources, Head Start is a trusted source of care, education, nutritious meals, and health services. Despite Head Start’s long history of bipartisan support, and demonstrated success, the U.S. Department of Health and Human Services (HHS) has a proposed new […]
Where on Earth is safest from global catastrophe?
Researchers have worked out the safest, most resilient country to be in during an apocalyptic event.
1984 Flag Maker Business WAVY Archive
Hampton Roads Virginia and Northeastern North Carolina News, Weather, Traffic and Sports.
1984 Virginia Beach Business Tax Changes WAVY Archive
Hampton Roads Virginia and Northeastern North Carolina News, Weather, Traffic and Sports.
Simon Edvinsson Makes Decision With Red Wings Contract Unresolved
Simon Edvinsson plans to attend Red Wings training camp without a new contract as Detroit's ongoing GM search continues to delay negotiations.
‘Science at the Fifty-Third Degree’ humanizes research advancements through conversation
Episodes highlight the collaborative nature of science, and expand accessibility of discoveries happening at the university.
AMID POLITICAL AD BOMBARDMENT, SAUSAGE DECLARES ITS CANDIDACY… FOR DINNER
As political advertising floods screens, phones and mailboxes ahead of the 2026 midterm elections, Johnsonville is entering the race for Dinner 2026 with a candidate of its own: Sausage. Backed by new research commissioned by Johnsonville suggesting Americans are overwhelmed by both politics and meal planning, Sausage is running on a core promise to simplify dinner decisions.
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
Auburn launches new AI course for business leaders in Birmingham
As AI (artificial intelligence) becomes increasingly integrated into our everyday lives, it's transforming everything from the way we search for information
How Is Hilton Worldwide's Stock Performance Compared to Other Leisure and Entertainment Stocks?
Hilton Worldwide has outperformed the Leisure and Entertainment industry over the past year, and analysts are cautiously optimistic about the stock’s prospects.
UC Berkeley Law event targets Trump science policies as ‘censorship’
The University of California, Berkeley School of Law organized an Aug. 25 discussion focused on resisting censorship and protecting academic freedom in scientific research.
Ministry of Science and ICT and NST unveil post-PBS missions for government research institutes by 2026
New mission-oriented R&D roadmap, portfolio, and governance reforms to be finalized and announced within the year
UT Researchers in Electrical Engineering and Computer Science Receive NSF CAREER Awards
Two researchers at the University of Tennessee, Knoxville, have received 2026 National Science Foundation CAREER awards.
Red Wings’ 2027 schedule: Earliest home opener in team’s history
ROCHESTER, N.Y. (WROC) — The Rochester Red Wings have released their 2027 schedule — and they have set the earliest home opener in their history. The team announced on Tuesday that their home opener at ESL Ballpark will be on Friday, March 26. They are set to begin playing against the Syracuse Mets. This start […]
‘Plastic pollution hotspots’ spawn a public health crisis across Latin America
Since China banned the import of plastic waste in 2018, plastic pollution has been having a growing impact on the people and ecosystems of Latin America. As the region imports an increasing amount of the world’s used and discarded plastic, new research shows that waste infrastructure in many countries is already buckling under the strain […]
Deconstructing LSD for Therapeutic Discoveries
UC Davis researchers have stripped down LSD to the base features responsible for its hallucinogenic and therapeutic effects.
What Makes Guardant Health (GH) a Compelling Bet?
Artisan Partners, an investment management company, released its second-quarter 2026 investor letter for the “Artisan Mid Cap Fund”. The letter can be downloaded here. Global equities rebounded sharply in Q2 2026, recovering from March lows as resilient economic data, strong corporate earnings, and continued AI investment improved investor sentiment despite inflation concerns, delayed rate cuts, and […]
Nearly half of depression risk factors overlap with physical illnesses, especially gut disease
QIMR Berghofer researchers have identified a strong genetic link between gut-related health conditions and depression in a study offering new insights into why physical illnesses often accompany the mental ...
How Merlin Entertainments is approaching GEO
The attractions business revamped its search strategy and grew its AI Overview visibility at six times the benchmark rate.
Six decades of politics (but little government)
The first aired episode of “Star Trek,” entitled “The Man Trap,” premiered on September 8, 1966 — 60 years ago today. I’m actually editing a political science fiction issue of The Forum right now, and it’s prompted to me think a lot about the ways that Trek deals with politics and government and what it’s offered us as commentary. The @smotus report is a reader-supported publication. To support this work, please become a paid subscriber. Subscribe The original TV series ran from 1966 to 1969. It had a loyal but modest following, but the audience grew substantially with the series in syndication for years after that. The franchise developed its first motion picture in 1979, followed by five sequels, and then a whole other series of films built around the “Next Generation” series that first aired in 1987. In recent decades, several more TV series have built up around it, including the current “Strange New Worlds,” now in its fourth season. Throughout the past six decades, the franchise has offered us a good many insights into US politics and international relations, although often disguised as science fiction yarns. The original series was largely a Cold War fable, with the United Federation of Planets (a stand-in for the US) perpetually at odds with the Klingon Empire (a stand-in for the USSR). The “Let That Be Your Last Battlefield” episode (1969) posited a planet divided into two races, largely indistinguishable to outsiders, but nonetheless constituting a brutal racial hierarchy. “Patterns of Force” (1968) showed a struggling planet where the leader had attempted to construct a benevolent dictatorship — literally Nazism without bigotry — and found that authoritarianism could not exist apart from hierarchy and oppression. (Relatedly, I’d put “Star Trek VI: The Undiscovered Country,” high on a list of dad films about the end of the Cold War, near “The Hunt for Red October.”) Get 20% off for 1 year Indeed, the original series itself was something of a political statement, with a multi-racial crew running the Enterprise, a diverse and largely peaceful Federation mostly free from want and oppression, and protected by Starfleet, an armed force whose scientific mission was at least as important as its military one. Famously, when Nichelle Nichols wanted to walk away from the role of Uhura on the original series, none other than Martin Luther King, Jr. met with her and urged her to remain on the show, discussing the importance of viewers seeing an intelligent Black woman as part of the command team three centuries hence. Later series in the Trek franchise offered a good deal of political commentary on their own, but probably none as explicitly and incisively as “Deep Space Nine,” which ran from 1993 to 1999. The episodes surrounding the Dominion War, especially the “In The Pale Moonlight” (1998), showed the compromises, sacrifices, and moral rot associated with winning even a just war — probably better than any series would until “Andor” (2022-25). In “Far Beyond The Stars” (1998), Captain Benjamin Sisko is somehow transplanted to the role of a science fiction writer in 1950s New York. The writer is frequently sidelined and his ideas stolen because publishers don’t want to credit a Black writer. Several series have depicted the secretive Section 31 — an unacknowledged black ops security force operating within Starfleet. These episodes often end up using Section 31 as a foil to show the dangers of a lawless group within a lawful society, even (especially) when that group posits itself as essential for everyone else’s freedom to continue. The current “Strange New Worlds” has played with a few political themes. I found the first two seasons of this show among the best that the Trek franchise has produced in decades, but this season and the last have really been struggling for ideas. Yet one interesting thread is the idea that the diplomatic and enlightened leadership style of Captain Christopher Pike will not work in all situations. “A Quality of Mercy” (2022), which I wrote about here, puts Pike in the middle of a battle with a Romulan vessel in an alternate timeline, and finds that Pike’s conciliatory style would actually make a lengthy and deadly war more likely, while a quick and more violent approach might have prevented the war. This season’s opener, “Valles Marineris,” shows a pre-lightspeed civilization locked in a war to the death with a neighboring planet. The idea of an alliance or a federation hasn’t even occurred to them — their ship’s commander is curious but doesn’t see it as an option. For a franchise as political as “Star Trek,” one thing we almost never see is the government. We get occasional glimpses of Starfleet’s council — mostly uniformed people at a rectangular table — but almost no sense of how the Federation is governed. Are there elections? Who is in the legislature? How much power does the president have? What kind of factional divisions do they wrestle with and how? The shows and films are pretty silent on this. We’ve seen a few military tribunals within Starfleet, but little about how civilians deal with crime and injustice. With recent years seeing some of the franchise’s more interesting plot lines and casts, it seems clear that Star Trek is still full of energy and ideas. Given the erosion of American democracy and the reshuffling of the international order, there’s no shortage of material for future shows to comment on. I’m not sure we should toast to 60 more years, but cheers to a show that continues to teach us about ourselves. Share
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