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NBA's Final Decision on Luka Doncic Suspension Causes a Stir
Luka Doncic received his 16th technical foul of the season, which warrants an automatic suspension.
Apple’s Worldwide Developers Conference returns the week of June 8
Apple today announced it will host its annual Worldwide Developers Conference (WWDC) online from June 8-12.
Binghamton ranked No. 1 public business school in New York state
The Binghamton University School of Management jumped ahead in the prominent Best Undergraduate Business Schools of 2026 ranking by Poets & Quants, placing No. 1 among New York state’s public business schools.
Extendend interview: Dr Roham Alvandi on Iran, Britain, and the futures that might have been
From Cold War power games to the cultural aspirations of the Pahlavi era, this extended conversation pulls back the curtain on the global forces that continue to shape - and be shaped by - Iran today. Dr Roham Alvandi is Director of the Iranian History Initiative at the London School of Economics and Political Science.
The war in Iran's impact on gas prices in Texas
NBC 5’s Phil Prazan tells us about the continued Texas impacts of the war in Iran as shockwaves are sent through the oil industry.
Man who bought $75 worth of Apple products from a stranger in a car park realizes he might be sitting on a small fortune
A tech enthusiast who bought a bunch of used Apple products off a stranger in a car park was left pleasantly surprised by the haul
Students compete in Virginia Science Olympiad State Tournament at UVA
The tournament’s events ranged from knowledge tests to building robots.
Students compete in Virginia Science Olympiad State Tournament at UVA
The tournament’s events ranged from knowledge tests to building robots.
Oil prices rise after Trump issues ultimatum and Iran threatens to close the Strait of Hormuz indefinitely
Oil prices rose Sunday after President Donald Trump threatened to “obliterate” Iran’s power plants if the Strait of Hormuz is not reopened by Monday evening.
Business closed after new Ohio law banning intoxicating hemp products went into effect
Senate Bill 56 grants law enforcement the authority to remove intoxicating THC products from unlicensed retail locations,
Why Have Patriots Not Done More To Address Pass Rush?
The New England Patriots had just 35 sacks last season, ranking near the bottom of the league in the regular season.
French Local Elections Are Yardstick for Far Right. Initial Results Are Mixed.
France’s municipal elections ended on Sunday evening. Full results were not expected for hours, but the first projections suggested the far right may not have made major gains.
‘Project Hail Mary’ blasts off with $80.5 million, a best for Amazon MGM, and the year
Studio estimates on Sunday say Amazon MGM's “Project Hail Mary” has topped the North American box office charts with $80.5 million in ticket sales — the second biggest ever for a non-franchise film.
Educational Service Center awarded Teach Computer Science 2.0 Grant
The Educational Service Center of the Western Reserve has been awarded $584,614 through the Ohio Teach Computer Science 2.0 State Grant, a competitive initiative funded by the Ohio Department of Higher Education. As part of an $8 million…
Israel Thought It Could Spur Rebellion Inside Iran. That Hasn’t Happened.
President Trump’s hopes that an Israeli plan to ignite an internal uprising against Iran’s theocratic government could bring the war to a swift end have so far been dashed.
The Times' top 25 high school baseball rankings
St. John Bosco and Sherman Oaks Notre Dame remain unbeaten in high school baseball
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Syracuse finalizing Gerry McNamara hire: Siena coach helped lead Orange to 2003 national championship
McNamara just finished guiding Siena to the NCAA Tournament, where it almost upset No. 1 Duke
Fear of immigration enforcement in NC keeps immigrants home, hurting Latino-owned businesses
US, Iran threaten more energy strikes as gas prices surge. What to know
As the U.S.-Israeli war with Iran enters its fourth week, the economic consequences continue to rattle markets.
Oil prices face new pressure as US and Iran trade threats
Trump said the US would attack Iran's power plants if it didn't reopen the Strait of Hormuz in 48 hours. Iran responded on Sunday with is own threats.
Kennedy’s latest MAHA-approved plan could supercharge peptide boom
He indicated that the FDA will soon widen access to the small proteins, which biohackers tout as therapies for a range of ills
3 restaurants open in Pittsburgh’s East Carson business district
Pittsburgh city leaders celebrated the opening of three new restaurants in the city’s East Carson business district on Friday.
Tom Steyer explains why he should be California's next governor
Tom Steyer sat down for an interview with California Politics 360 for a wide-ranging conversation on his run to be the state's next governor.
Treasury secretary defends U.S. military actions in Iran: 'Sometimes you have to escalate to de-escalate'
Scott Bessent said "all options" were on the table to secure Kharg Island.
Readers Respond to Health Insurance Chaos for Providence Customers
“Only other questions I have is who is starting the class action and where can I sign up?”
American football takes for ever. In which other sports do you spend most of your time not playing the game?
The long-running series in which readers answer other readers’ questions on subjects ranging from trivial flights of fancy to profound scientific and philosophical concepts
Natrona County health and food inspections (3/13/26–3/19/26)
CASPER, Wyo. — The Casper-Natrona County Health Department inspects restaurants, grocery stores, convenience stores, mobile food units, commissaries and
iPad 12 With A18 Chip for Apple Intelligence is 'Still Coming This Year'
Apple has updated a wide range of products and accessories this month, but there is still no entry-level iPad 12 with Apple Intelligence support. Fortunately, Bloomberg's Mark Gurman today said an iPad with an A18 chip for Apple Intelligence is "ready to go" and "still coming this year". An earlier report from Macworld claimed that the iPad 12 will actually have an A19 chip.
'Saturday Night Live UK' aims to take a comedy hit across the pond. The first verdicts are in
A British version of “Saturday Night Live” has debuted to largely positive reviews. The first episode of “SNL UK” was hosted by Tina Fey, a veteran of the American show, and stuck closely in...
\'Saturday Night Live UK\' aims to take a comedy hit across the pond. The first verdicts are in
A British version of “Saturday Night Live” has debuted to largely positive reviews. The first episode of “SNL UK” was hosted by Tina Fey, a veteran of the American show,
The best seafood restaurant in every state, according to Yelp
Yelp picked the best seafood restaurant in every state based on customer reviews.
Cuba Says Its Military Is Prepared as Trump’s Threats Multiply
A senior Cuban official said the country is preparing for a possible military assault as President Donald Trump increases economic pressure on the government in Havana and suggests it could be the next US target after Venezuela and Iran.
Politics chat: Trump's mixed messages on the Iran war, the latest on DHS funding
We look at President Trump's mixed messages on the war with Iran, plus the latest on Department of Homeland Security funding, which Congress has frozen over his immigration enforcement policies.
Scientists twisted a mysterious superconductor and got a shocking result
A decades-old superconducting mystery just took a surprising turn. Strontium ruthenate, a material that conducts electricity with zero resistance at low temperatures, has long puzzled scientists with hints of an exotic, complex superconducting state. But by carefully twisting and distorting ultra-thin crystals, researchers found something unexpected: the material barely reacted at all. This challenges years of assumptions and suggests its behavior may be far simpler—or far stranger—than previously thought.
Pompey's hopes of staying up now unsure
BBC Radio Solent commentator Andrew Moon gives his thoughts following Portsmouth's 6-1 defeat at Queens Park Rangers in the Championship.
A tribute to Scott Ostler, columnist, colleague, friend and sports wit
In Bruce Jenkins’ experience, there was never a teammate quite like fellow San Francisco Chronicle columnist Scott Ostler, who retired last week.
We Took Our Three-Year-Old On A Long Haul Flight, And It Was Amazing!
We took our three year old on his first long haul flight in nearly two years. It went so much better than I could have anticipated!
The Times' final top 25 high school boys' basketball rankings
Sierra Canyon, the state Open Division champion, finishes No. 1 in The Times' final 2025-26 high school boys' basketball rankings.
Southland girls' basketball final rankings for 2025-26 seaosn
A look at the top 20 high school girls' basketball teams in the Southland, led by Open Division state champion Ontario Christian.
Outgoing MSPs leave Holyrood with relief, regret and unfinished business
A record 42 MSPs are stepping down, from grandees to first timers - they share their reasons why.
49ers News: 25 more Sundays until NFL football is back
Your daily San Francisco 49ers news for Sunday, March 22nd, 2026
EA-US Politics Podcast: Mr Trump Goes to War
50-minute analysis of the chaos and destruction of Donald Trump and his inner circle as self-declared "President of Peace" wages war on Iran
The war on Iran is in its fourth week. Here’s what to know
Three full weeks of the war the US and Israel launched against Iran have shocked the world oil market, pierced a sense of safety in parts of the Middle East, and claimed the lives of US service members and civilians in multiple countries.
Businesses worried as fuel prices rise
An increase in fuel prices amidst the US-Israel war with Iran is affecting businesses in the UK.
'Education and communication key to voter turnout' in Jersey
Researcher says more work is needed to increase Jersey's low voter numbers.
Barricade That Kept Out the Far Right in France Is Crumbling
Franck Leclere made his way through the timber-framed houses of Chalons-en-Champagne and joined a crowd of people in symbolic white shirts to demonstrate against the rise of the far right in France.
Europe’s trade with Iran: Which countries do the most business with Tehran?
EU–Iran trade fell to its lowest level in two decades in 2025 due to sanctions. Trade continues on a limited scale, with Germany accounting for the largest share.View on euronews
The Antidote to Our Growing Crises Must Transcend Politics
Each day, the challenges in our nation pile up. In just recent weeks, there has been the ongoing war in Iran and the Middle East, and ongoing debates about the growing negative impact of the Internet, looming AI challenges, and the Epstein files. The anticipation of divisive, even ugly, midterm elec...
France Is Voting for Thousands of New Mayors. Here’s Why It Matters.
The far-right party had first-round successes in several cities, but so did the far left. Sunday’s second round may clarify who has real momentum.
As War Disrupts India’s Gulf Ties, Economy Faces ‘New Broadside’
Generations of Indian workers and businesses have turned the Arab side of the Gulf into a vital appendage of their own country.
Marc Abrahams, founder of the satirical Ig Nobel Prizes: ‘Scientists in the US are very angry. People are waking up’
The awards are moving to Switzerland, because their founder believes he can no longer guarantee the laureates’ safety in the United States
Bridging medical realities in the study of technology and health
Anthropologist and MIT Associate Professor Amy Moran-Thomas studies medical technologies and how they fail to reach some communities. “What anthropology has to offer the world, and other knowledge systems, is the insights of people that might be missing from many accounts,” she says.
Black Family Wellness Expo brings people together for day of health education
The Black Family Wellness Expo returned to Roselawn Saturday.
Digimon Story: Time Stranger large-scale expansion DLC announced
Publisher Bandai Namco and developer Media.Vision have announced a large-scale expansion downloadable content for Digimon Story: Time Stranger. It will launch in 2027.
Friction without contact discovered as magnetic forces break a 300-year-old law
Researchers have uncovered friction without contact—driven entirely by magnetic interactions. As two magnetic layers slide, their internal forces compete, causing constant rearrangements that dramatically increase resistance at certain distances. This creates a surprising peak in friction instead of a steady rise, breaking a long-standing physics law.
Webb Telescope spots “impossible” atmosphere on ancient super Earth
Astronomers have uncovered surprising evidence of a thick atmosphere surrounding TOI-561 b, a scorching, fast-orbiting rocky planet once thought too extreme to hold onto any gas. Using NASA’s James Webb Space Telescope, researchers found the planet is far cooler than expected for a bare rock, hinting at a heat-distributing atmosphere above a churning magma ocean. This strange world—where a year lasts just over 10 hours and one side is locked in eternal daylight—may even be rich in volatile materials, behaving like a “wet lava ball.”
Business investment in the era of digital transformation
The weak performance of business investment across the OECD since the Global Financial Crisis holds back potential growth. However, it masks a strong investment dynamic in digital assets such as hardware, software, and databases. This column describes how this divergence between digital and non-digital assets has intensified from the mid-2010s. The strong investment performance of the US relative to the rest of the OECD is almost exclusively a digital phenomenon. A ‘digital divide’ is emerging, where laggard countries are accumulating digital capital per worker more slowly than those with higher initial starting levels.
Senate rejects Trump-backed measure to ban trans athletes in female sports
The Senate on Saturday rejected an amendment to a far-reaching voting bill that would have barred transgender females from playing in girls’ and women’s sports.
Iran launched missiles at US-UK military base in the Indian Ocean. Here’s what that says about its capabilities
Iran’s attempt to strike a US-UK base over 2,000 miles (over 3,000 kilometers) off its coast has renewed questions about Tehran’s military capabilities and how far its missiles can reach.
My postpartum mental health meant I spent five months on a mother and baby unit
Sofii Lewis was diagnosed with postpartum psychosis tendencies and OCD after giving birth.
Fantasy baseball updated Reliever rankings for 2026
Catch up on USA TODAY Sports' updated 2026 Reliever rankings ahead of the fantasy baseball season.
Donald Trump Is Nothing Like Robert Mueller
The absurdity of a man who avoided Vietnam due to “bone spurs” dancing on the grave of a decorated combat veteran
47th annual Utica University science fair shows area students are smarter than ever
Four dozen science projects from 60 students from eight area schools competed for the top prizes at the Donohue Concourse underneath the Frank Gannett Library. Some of the topics may have changed over the years — there were no baking soda volcanoes — but the students still displayed their projects on decorated posterboard for staff, family and the judges to see. The projects were split between the junior division — 7th and 8th grades — and the senior division — 9th through 12th grades.
'American people long for civility,' former VP Pence tells University of Tennessee students
In a frank discussion about America's future. Pence says \
G.O.P. Bid to Target Transgender Athletes Falls Flat in the Senate
In moving to bar transgender women and girls from women’s and girls’ sports, Republicans sought to put Democrats in an awkward political spot on a sensitive issue ahead of the midterm elections.
Senate blocks amendment on transgender athletes during weekend session
The amendment that was blocked by a 49-41 vote would create potential penalties for educational institutions that receive federal funding
Senate rejects Trump-backed measure to ban trans athletes in female sports
The chamber considered adding the measure to a far-reaching voting bill supported by the Republican president.
Shame on ABC for casting Taylor Frankie Paul on 'The Bachelorette' — they're getting what they deserve
Trump Is Finally Eyeing an Exit From Iran. But Will He Take It?
President Trump says he is considering “winding down” operations in Iran. But many of his original war goals remain unaccomplished.
Gov. Stein announces $8.5 million for WNC small business recovery after Helene
The funding will assist 13 projects through the North Carolina Department of Commerce’s Small Business Infrastructure Grant Program, continuing the state’s response to the impacts of Hurricane Helene.
Democrats block SAVE America Act amendment to bar transgender athletes in women’s sports
Senate Democrats voted Saturday to defeat a Republican-sponsored amendment to the SAVE America Act that would prohibit transgender athletes from participating in girls’ or women’s sports, an …
Minecraft World Opening 2027, First Look at $70 Million Project
Theme park lovers who yearn for the mines will have their wish granted in 2027 with the debut of Minecraft World, based on the popular building video game.
Health insurance jargon can be frustrating and confusing – here’s how to navigate it
What plan you pick has a huge impact on what you will end up paying.
ENTERTAINMENT: Walton Arts Center’s lineup features 5 Broadway shows
Season subscribers will also “be the first in line to guarantee your seats for the Northwest Arkansas debut of ‘Wicked,’” already on the schedule for the 2027-’28 season.
'The Bachelorette' canceled: Taylor Frankie Paul's season pulled after 2023 domestic violence video surfaces
Taylor Frankie Paul speaks out as controversy grows, with "The Bachelorette" canceled and filming paused on "Secret Lives of Mormon Wives."
Thune, GOP blast Dems in DHS standoff as Lankford says they fear ICE over Iran
Sen. James Lankford, R-Okla., accused Senate Democrats of being afraid of ICE than Iran as the DHS shutdown hit its 36th day, as Republicans again offered another compromise deal to reopen.
Orange County restaurants shut down by health inspectors (March 12-19)
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Ranking 5 most likely March Madness upsets in NCAA Tournament second round
The second round of 2026 NCAA Tournament is underway. Here's a look at the five most likely March Madness upset predictions in the Round of 32.
Franklin Templeton CEO Jenny Johnson on the values needed to keep a billion-dollar business in the family
Jenny Johnson is CEO of $12 billion family-run asset management business Franklin Templeton, which oversees nearly $2 trillion in assets. Growing the company and succeeding in the role took everyone in the family, including herself, putting their egos aside.
UFC London’s Felipe Franco promises entertainment after teammate Jailton Almeida’s release: ‘They want to see blood’
Felipe Franco battles undefeated Mario Pinto at UFC London
Jenny Johnson, third-generation Franklin Templeton CEO, on managing trillions for the family business
Franklin Templeton CEO Jenny Johnson leads a global fund manager with nearly $2 billion in assets and a 79-year-old family business started by her grandfather.
An Iranian-American political science expert talks about Iran's nuclear program
NPR's Scott Simon speaks to Ariane Tabatabai, the Public Service Fellow at Lawfare, about the nature of Iran's nuclear program, and whether it, as President Trump has said, posed an "imminent threat."
The Joe Kent saga lays bare the real Trump derangement syndrome
Washington's Kent resigning from the nation's security team seemed like an accountability moment. Instead, it demonstrated how President Trump isn't held responsible for anything.
March Madness games today: Ranking the 16-game Women's NCAA Tournament schedule for Saturday
Syracuse vs. Iowa State and Princeton vs. Oklahoma State leads the best Women's NCAA Tournament games to watch on Saturday.
Health system operating in full emergency mode following Iranian missile impacts in south
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Exclusive Blue Lagoon Skin Science Discount as Seen on TODAY
Shop TODAY's Adrianna Brach gets a behind-the-scenes look at the brand's innovative products.
Amid US-Israel war with Iran, what will Pakistan do?
Pakistan has a defense pact and a friendship with Saudi Arabia, but shares a border and social ties with Iran. If the Saudis ask for help against Iran, Pakistan would be stuck. How is it managing these relationships?
As Starmer faces war overseas, his party can't find peace at home
British politicians tend to stick together during dangerous moments abroad. In 2026? Not so much.
Katie Couric on aging, being a grandmother and the importance of early cancer screenings
Katie Couric tells USA TODAY about the joys of aging, being a grandmother and why early cancer screening is important – so others can age well, too.
When health insurance costs $2,500 per month, families make tough choices
A self-employed couple already had to dip into retirement savings for health costs. Now, they are skipping vacations and canceling streaming to afford health insurance.
The insular bubble of caucuses and assemblies
Nearly 30 years ago, then-Federal Reserve Chairman Alan Greenspan coined the term “irrational exuberance” to describe the overheated stock market. That descriptive phrase could also apply to much of the political realm. The hype in politics often grossly exceeds the reality on the ground. In that vein, let’s focus on Colorado’s precinct caucuses held earlier […]
Trump and the politics of death
COVID, gun violence and Iran reveal a governing instinct based on authoritarian violence disorder
Paul Freud on using art to understand wars and politics
The London-based artist and great-grandson of Sigmund Freud discusses forging his own artistic language and finding inspiration in global conflict.
You’ve Lost Your Health Insurance. It Shouldn’t Have Been a Surprise.
You would think you’d get texts, emails, phone calls and letters if your insurer was about to drop you. But you may be wrong.
High Gas Prices, Driven Up by the Iran War, Loom Over the Midterms
The war has complicated the Republican message on affordability. Democrats see an opportunity to drive their economic message while tying President Trump to an unpopular overseas conflict.
Inside Trump’s most difficult war decision yet: whether to put boots on the ground in Iran
In near-daily briefings with top military officials at the White House, President Donald Trump has reviewed options that include sending American troops into Iran.
Health Ministry: 303 people hospitalized in war with Iran and Hezbollah in past 24 hours
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Calculate Your VO2 Max at Home in Just 5 Minutes, No Complex Lab Tests Needed
It's one of endurance sport's most talked about yet elusive numbers, until now. A simple power test will spare you a costly trip to a performance lab for specialist VO2 Max testing.
GOP, Dems battle over Trump's SAVE Act. But who will it really help?
The president says the election security bill 'will guarantee the midterms' for Republicans. Available data is far less clear cut. Here's why.