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Aston Martin boss Newey reveals health issues led to 'difficult period'

Adrian Newey has revealed he was battling health issues during his first year at Aston Martin, leading to a "difficult period" as the team also struggled to adapt to Formula 1's 2026 regulations.

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Jul 1 • 8:09 AM EDT • Health • espn.com
Sony will cease production of discs for new PlayStation games in 2028

New games sold for PlayStation consoles will only be available digitally and won’t be sold on discs effective January 2028, Sony has announced. The move applies to all PlayStation games released from that point on, including those made by Sony and those released by third parties. The PlayStation group calls the change “a natural direction for Sony Interactive Entertainment to adapt to consumer trends as the general preference for digital media significantly outpaces physical discs,” according to a PlayStation blog post reviewed by Game File in advance of its publication. As movies, TV and music have shifted from physical media to an age of downloads and streaming, Sony’s move could speed the demise of physical media in a gaming. The industry has offered consumers games via cartridges, cassettes, floppy discs, CDs, DVDs and Blu-Rays across a 50-year stretch. Sony has been reporting to investors in recent years that PlayStation games have been increasingly purchased as downloads, not as discs. The most recent figures show nearly four in five purchases of full games for PlayStation 4 and PlayStation 5 were purchased digitally in the past year. Stats like that may cause today’s news to carry an air of the inevitable. But Sony’s declaration for 2028 is still likely to produce a shock, as the biggest gaming platform on the planet that uses game discs leaves them behind. Discs going away, but the fate of game boxes is unknown Sony is committing to still selling games in physical retailers even after they drop discs in 2028. Just how those games will be sold—in boxes with codes inside, as cards marked with digital redemption codes—is unclear. Digital games will also continue to be sold in the online PlayStation Store. New games released for PlayStation consoles prior to January 2028 will be unaffected by the policy change, Sony says. That means the PS5 games of 2027, be they a new Madden, a new God of War, a new Call of Duty, a new Sly Cooper (one can dream?), would still potentially be offered on disc. PlayStation 6 implications Sony’s timeline for a transition to a no-disc era will also spin up more speculation about the timing and configuration of Sony’s next-generation console, the probable PlayStation 6. “This pretty much guarantees that PS6 won’t arrive until 2028 at the earliest,” Piers Harding-Rolls, senior games research analyst at Ampere Analysis tells Game File. Harding-Rolls also concludes from today’s news that “the base version of a PS6 will not include a physical media drive,” as Sony looks to keep costs down on the device. Sony itself is saying nothing about the PS6 today: not its timing, nor how it might or might not support internal or external disc drives in order to run disc-based PS4 and PS5 games, should the console be backwards compatible. The many signs this was coming Industry support for games being released on physical media has been waning. As has consumer interest in them. PC games effectively went all-digital years ago, thanks to the popularity of playing games through Steam and other digital storefronts. The Covid-19 pandemic and the lockdowns that kept much of the global population home helped shift shopping patterns toward downloads. Sony’s own data shows PlayStation game downloads being an uncommon consumer choice a decade ago and now becoming the norm. On consoles, physical media has been in such decline that Sony and Microsoft both launched their current gen Xbox Series and PS5 consoles in 2020 with cheaper versions that lacked disc drives. In early 2024, Phil Spencer, then head of Xbox, told me that ““[w]e ship games physically and digitally, and we’re really just following what the customers are doing.” He added that the game industry had become an outlier in still supporting disc-based entertainment, even as movies and TV have bailed on discs in favor of downloads and steaming: “Gaming consoles themselves have kind of become the last consumer electronic device that has a drive. And this is a real issue, just in terms of the number of manufacturers that are actually building drives and the cost associated with those. And when you think about cogs that we’re going to go put in a console—and as you have fewer suppliers and fewer buyers—the cost of the drive does have an impact.” Last year, the Nintendo’s Switch 2, which uses cartridges rather than discs, introduced the concept of game-key cards, which are physical media that contain no game, just a prompt for a download. Even disc-based games aren’t what they once were, now frequently containing just stubs of games rather than the whole thing. The website Does It Play has tested over 3000 games and found that, for example, that the disc version of this year’s hit 007: First Light, only contained the game’s first mission, with the rest needing to be downloaded. Beyond all that, last week brought the news that Grand Theft Auto VI, likely the biggest game launch this decade, will debut for PS5 and Xbox Series without a disc-based version. Today’s big news comes to you for free. Game File is a reader-supported publication. To receive new posts and ensure more of my work is possible, please consider becoming a free or paid subscriber. Subscribe Discs helped define PlayStation However the trends in entertainment may be going, it is still remarkable to see PlayStation ditch discs given their importance in PlayStation history: In the late 1990s, the first PlayStation’s support for games on relatively cheap CD-ROMs instead of traditional game cartridges allowed the upstart console to outmaneuver cartridge-based systems from Nintendo and Sega, as it drove down game prices down in the process. (The cheaper disc format even prompted Final Fantasy VII maker Square to taunt Nintendo in a magazine ad, saying that if the game was “available on cartridge, it’d retail for around $1200.”) PlayStation devices often doubled as machines for watching movies and TV on the latest disc-based formats. In the late 2000s, for example, Sony’s pricy PS3 gained traction as a go-to device for playing then-novel Blu-Ray discs. In 2013, Sony effectively roasted the digital game-sharing restrictions proposed by rival Microsoft for its upcoming Xbox One console by showing how games could be shared for the then-upcoming PS4. In a 21-second clip that has over 20 million views on YouTube, one PlayStation executive simply handed a game box—presumably with disc inside—to another, who said “thanks.” Sony’s possible motivations The PlayStation announcement today cites “consumer preferences” and a shift away from discs among “the broader entertainment industry,” but does not delve into the decision-making process that brought Sony to this point. Sony is not discussing the economics of this move (I asked!), but there are a number of potential factors: Abandoning discs will spare Sony the cost of manufacturing and shipping them, which analysts and industry veterans I spoke to said could account for $1 or so of a game’s retail price. For first-party games, that’s direct savings for Sony, though the amount is limited by the winnowing percentage of people who were even buying the disc-based versions. For third-party games, Sony could pass the savings on to partners or just retain the better profit margin for themselves. As the 2024 comments from Phil Spencer alluded to, leaving discs behind could mean leaving disc-drives behind, allowing Sony to produce consoles more cheaply. Switching to digital-only for games could diminish the risks of copies of new games leaking. It would also seemingly make second-hand sales of used games impossible, pushing more people to buy their own copies of games. These economic benefits for Sony could be boons for the games industry overall, Ampere analyst Piers Harding-Rolls tells Game File. Among other things, it could free publishers and retailers from having to worry about securing an inventory of game discs when trying to sell games, he noted. “If there is a way to streamline the business of games retail, I generally think it’s a good thing for the industry as it removes unnecessary costs,” Harding-Rolls said. “This will help offset pressure on margins from other directions – development and staffing costs for example.” Should the industry shift from game boxes that contain discs to smaller, cheaper game cards, Harding-Rolls said, that reduces pressure on publishers and retailers. “The advantage of everything going digital for the industry is that sales can be tracked much more easily and there is less commercial risk for publishers wanting to continue selling via retail,” he said. The shift to no discs will also likely impact game development timelines, as developers will no longer face the same urgency to have a build ready to submit to PlayStation for the production of a disc, as industry experts noted around GTA VI’s no-disc news last week. Instead, projects may gain weeks of development time, in the event delivery deadlines for platform approval move closer to release date. Preservationists’ likely worries While millions of gamers have shifted to digital, there are still people who associate game discs—and only game discs—with actual ownership of PlayStation games. That portion of the gaming community spoke up last week about wanting to buy a version of GTA VI that they could hold in their hands, could lend to a friend and could potentially pop into a well-preserved PS5 console three decades from now and still see it run. Such gamers didn’t want to worry that they’d merely purchased a digital copy that could lose access to the game if, say, the company behind the game someday turns of the servers that transmit downloadable copies. Digital copies of games are inherently less long-lasting, because consumers aren’t actually buying a game (on a disc), just buying access to the game. The fine print in online gaming shops notes this, as does a recent law that went on the books in California in 2025. That lasw requires game publishers doing business in the state to refrain from words like “sell” when offering digital copies of games, unless they explicitly tell consumers that what’s being sold isn’t the game itself but a potentially revocable license to access it. A Sony spokesperson noted to Game File that “[w]ith all digital content, including games, movies, and music, players are purchasing a personal license for non-commercial use.” Regarding the fears of PlayStation games being lost to time in an all-digital era, the rep also noted that Sony remains “committed to delivering experiences from past generations to the new platforms our players are using.” They noted that PlayStation has used emulation and remasters to keep offering its classic games to modern gamers. It’s true that many consumers have become accustomed to not having physical copies of new music albums or movies, but the relative precariousness of digital copies of games is in fact being highlighted today by…. Sony’s other big announcement: the upcoming closure of the PS3 and PS Vita online stores Sony said today that it will be closing the online marketplaces for its PlayStation 3 console and PS Vita handheld in most countries in July 2027 (sooner elsewhere: August 2026 for the PS3 store Mexico, Honduras and Nicaragua; late 2026 for PS3 in other Latin American countries and the Middle East). “We know this news may be disappointing to PS3 and PS Vita players who hold a special place in their hearts for this generation of gaming,” Sony said in its announcement, saying the move “was not an easy decision for us to make.” Sony said that PS3 and Vita marketplaces “are no longer able” to support modern commerce systems, prompting a “need” to close the shops and focus on more modern PlayStation platform stores. The news may spark some deja vu. Sony announced back in March 2021 that it planned to take the PS3, Vita and PlayStation Portable marketplaces offline that summer. The move would have caused some 2,000 digital-only games to become unavailable for new purchasers, according to a VGC analysis at the time. Fans complained loudly. By April 2021, Sony walked back the PS3 and Vita shop closures, with then PlayStation boss Jim Ryan saying “it’s clear that we made the wrong decision here.” This time around, Sony is giving a longer notice period in most regions. The closure of those stores is still likely to cut off access to new purchases of digital-only PS3 and Vita games. The current PlayStation 5 marketplace sells PS5 and PS4 games, as well as a selection of PS1 and PS2 games. It does not sell PS3 games, because games for that platform can’t run on the system (some are offered via a PlayStation Plus streaming option). Vita games also aren’t sold via PS5. Sony says digitally purchased PS3 and Vita games will be downloadable after the stores’ shutdowns “for the foreseeable future.” Sony’s move contrasts with Microsoft’s Xbox platform, which continues to sell and support games from all four Xbox console generations. But it puts it in line with Nintendo, which disabled purchases in the marketplace for its Wii console (a contemporary of the PS3) in 2019. Nintendo discontinued purchases in the online shop for its 3DS portable (a contemporary of the Vita) in 2023. The big questions about Sony’s 2028 post-disc era Will Microsoft follow suit, ending support for new disc-based games on Xbox platforms and therefore all game consoles, too? Whether Microsoft does or not, will third-parties that can no longer release games on discs for PlayStation, simply ditch the disc options across the board? Given the GTA VI no-disc experiment launching this November, will more game publishers decide to forgo disc-based offerings even in 2027? How will no-disc PS5/6 games be packaged and sold in brick-and-mortar retail stores? What becomes of game sharing in an all-digital era? Will Sony modify its current set-up, which currently allows some sharing of digital games across a pair of consoles, to allow more casual lending? (See for example, Nintendo’s year-old system of letting players lend a digital game to another player in a “family group” for up to 14 days.) Will there be a version of a PS6 with a disc drive? Or will a drive be offered as an add-on? And how will gamers who want to retain access to PS4/PS5 disc-based games react to whichever configurations Sony chooses to offer? What will the final disc-based PlayStation game be?

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Jul 1 • 8:00 AM EDT • Technology • gamefile.news
How eggs became the latest campaign issue in Texas' Senate race

Republican Ken Paxton says his settlement holds producers accountable. Democrat James Talarico says Republicans still haven't lowered grocery bills.

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Jul 1 • 7:00 AM EDT • Politics • dallasnews.com
Apple ‘Hide My Email’ Vulnerability Reveals Peoples’ Real Email Addresses

”Hide My Email users deserve to know that it may be possible for attackers to discover their hidden email addresses,” the person who reported the issue said.

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Jul 1 • 6:00 AM EDT • Technology • 404media.co
Claude Helped a Hacker Find a Way to Issue Tickets to Almost Every US Music Festival

A researcher found that using Anthropic’s Claude Opus 4.7, he could break into the website of Front Gate—used by every festival from Lollapalooza to Bonnaroo—and freely issue any ticket he chose.

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Jul 1 • 6:00 AM EDT • Technology • wired.com
Hospital sued after drug addict nurse allegedly causes death of two patients

An emergency department nurse at Heritage Valley Sewickley Hospital is accused of stealing drugs and neglecting patients, causing at least two fatalities. A lawsuit filed by two whistleblowers further alleges that hospital leadership covered for the drug-dependent nurse.

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Jul 1 • 1:12 AM EDT • Health • healthexec.com
Servers recalled after glitch results in radiologists reading images for wrong patients

The issue could cause a reader to unintentionally report on the wrong patient when using interactive applications, according to a notice from the FDA.

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Jul 1 • 12:02 AM EDT • Business • radiologybusiness.com
Garden City restaurant violations include black mold, unsafe foods

Wayne County health reports show violations at Garden City eateries, including improper food storage, equipment malfunctions and hygiene issues.

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Jul 1 • 12:01 AM EDT • Health • detroitnews.com
Dolly Parton Is ‘Trying to Do Too Much Too Soon’ Amid Health Issues: She’s ‘Still Very Unsteady’
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Jun 30 • 9:43 PM EDT • Health • yahoo.com
South Fulton leaders hopeful new investment will address crucial healthcare gap on Atlanta's south side

For decades, residents and officials alike have raised the issue regarding limited access to hospitals and specialty care in South Fulton. Now, county leaders and health officials are earmarking funds to address the situation.

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Jun 30 • 5:17 PM EDT • Health • cbsnews.com
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What’s being built, bought and planned in Ascension Parish

Here are the latest property transactions, issued permits and upcoming business-related events in Ascension Parish. Property transactions Local organization American Soldiers Evaluation Services purchased a 4,000-square-foot office building on East Josephine Street from Nolan and Sharon Aikens for $400,000. American Soldiers Evaluation Services’ CEO, Dr. Sandrine Nkouga, represented the buyer in the transaction. ASES provides […]

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Jun 30 • 4:00 PM EDT • Business • businessreport.com
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Best of the Beehive: Art & Entertainment

Our 2026 Best of the Beehive Issue is here! ead on for all winners and finalists from the Arts & Entertainment category.

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Jun 30 • 3:57 PM EDT • Entertainment • saltlakemagazine.com
Politics: High Cost Of Healthcare And The Political Fallout

Americans are grappling with a rising cost in healthcare. For the first time in five years, fewer than half of Americans can consistently afford healthcare. That’s according to the latest data from Gallup. The cost of healthcare in the US remains higher than any other large, wealthy country. According to a report from the Department of Health and Human Services, five million fewer people are enrolled in marketplace plans for 2026, compared to last year. That’s as average premium costs rose about 58%.With health care costs increasingly becoming a stress for Americans, voters are now making the issue a top priority at the ballot box. And it’s an issue that crosses party and geographic lines. According to new polling from The Century Foundation, 71% of Democrats, 66% of Republicans and 75% of rural voters agree that reigning in hospital costs should be a top priority for lawmakers. While new polling from Ipsos and Axios suggests that a majority of Americans say they’re more likely to vote for candidates in November who will lower their health costs.How will the issue of healthcare shape the midterms? And how are Americans grappling with the cost of their health?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a.

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Jun 30 • 3:24 PM EDT • Health • npr.org
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Politics: High Cost Of Healthcare And The Political Fallout

Americans are grappling with a rising cost in healthcare. For the first time in five years, fewer than half of Americans can consistently afford healthcare. That’s according to the latest data from Gallup. The cost of healthcare in the US remains higher than any other large, wealthy country. According to a report from the Department of Health and Human Services, five million fewer people are enrolled in marketplace plans for 2026, compared to last year. That’s as average premium costs rose about 58%.With health care costs increasingly becoming a stress for Americans, voters are now making the issue a top priority at the ballot box. And it’s an issue that crosses party and geographic lines. According to new polling from The Century Foundation, 71% of Democrats, 66% of Republicans and 75% of rural voters agree that reigning in hospital costs should be a top priority for lawmakers. While new polling from Ipsos and Axios suggests that a majority of Americans say they’re more likely to vote for candidates in November who will lower their health costs.How will the issue of healthcare shape the midterms? And how are Americans grappling with the cost of their health?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a.

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Jun 30 • 3:24 PM EDT • Politics • npr.org
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Green intends to veto just four bills

The measures span issues in education, housing, school facilities and the rainy day fund

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Jun 30 • 2:15 PM EDT • Politics • spectrumlocalnews.com
Police chief issues statement after Dianna Russini mentioned NFL coach, avoided ticket

NFL reporter Dianna Russini mentioned texting with an NFL coach after getting pulled over for being on her phone.

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Jun 30 • 1:54 PM EDT • Sports • syracuse.com
Kathie Lee Gifford admits she 'wanted to die' after misdiagnosis and multiple surgeries for chronic pain

Kathie Lee Gifford reveals she was misdiagnosed for a year and treated for a spinal issue before doctors discovered her hip had deteriorated to "ash."

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Jun 30 • 12:36 PM EDT • Health • foxnews.com
Tom Kean Says Depression Led to Long Absence From Congress

After months of mystery, the New Jersey representative broke his silence about the undisclosed health issue that prompted his 117-day absence.

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Jun 30 • 11:34 AM EDT • Politics • nytimes.com
Ward Issues Statement on U.S. Supreme Court Ruling on Save Women’s Sports Act

Sen. Judy Ward (R-30) issued the following statement today regarding the recent ruling by the Supreme Court of the United States in West Virginia v. B.P.J.:

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Jun 30 • 10:57 AM EDT • Sports • senatorjudyward.com
Who’s building and who’s buying in Greater Baton Rouge

Here are the latest issued permits and property transactions in East Baton Rouge and Ascension parishes. East Baton Rouge Parish The East Baton Rouge Parish Sheriff’s Office purchased the pr… Already an INSIDER? Sign in. Already an INSIDER? Sign in

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Jun 30 • 10:44 AM EDT • Business • businessreport.com
Ohio Department of Health issues safety tips for high temps

Certain individuals, like kids and elderly people, are at higher risk.

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Jun 30 • 10:35 AM EDT • Health • spectrumnews1.com
VA Primary Care adds virtual reality to Veterans’ Mental Health Toolkit

Virtual reality devices help Veterans by offering additional ways to manage issues affecting their physical and mental health.

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Jun 30 • 10:30 AM EDT • Health • news.va.gov
Supreme Court Strikes Down Limits on Political Party Spending

At issue in the case was a post-Watergate law that Congress passed to limit the amount of money individuals can give to political parties.

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Jun 30 • 10:28 AM EDT • Politics • npr.org
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Supreme Court upholds state laws banning transgender athletes

The Supreme Court on Tuesday issued a decision to uphold state laws barring transgender girls and women from playing on school athletic teams.

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Jun 30 • 10:08 AM EDT • Sports • espn.com
US supreme court upholds laws excluding trans women from competing in female sports

Justices voted to overturn judgements issued by lower courts in favor of trans students who sued after being barred from competing in West Virginia and Idaho

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Jun 30 • 10:02 AM EDT • Sports • theguardian.com
SoFi Introduces Small Business Loans to Help Members Pursue Their Business Ambitions

SAN FRANCISCO, June 30, 2026--SoFi Technologies, Inc. (NASDAQ: SOFI), the everything app for digital financial services, today announced the launch of SoFi Small Business Loans, to help entrepreneurs and small business owners access fast, transparent financing to run and grow their businesses.

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Jun 30 • 9:00 AM EDT • Business • finance.yahoo.com
Half of states sue over Medicaid work requirements

FDA peptide panelists, a new study on Covid and flu shots, and more health news from Morning Rounds

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Jun 30 • 8:14 AM EDT • Health • statnews.com
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New Molecular Monitoring Offers Scientists a ‘Live Video’ Look at Cells

‘This approach allows us to collect molecular information from precise locations while minimizing disruption to the tissue, making it possible to monitor bi ...

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Jun 30 • 7:15 AM EDT • Science • today.uconn.edu
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New study: Americans’ perceptions of the health harms of climate change

Awareness of climate change as a health issue is increasing, but polarization on the topic is, too.

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Jun 30 • 7:01 AM EDT • Health • climatecommunication.yale.edu
Adrian Newey: Aston Martin chief speaks on his health issues and confirms F1 team set for for big Hungarian GP car upgrade
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Jun 30 • 6:18 AM EDT • Health • skysports.com
US Supreme Court to decide legality of state transgender sports bans

The U.S. Supreme Court is set on Tuesday to decide the legality of state ​laws in West Virginia and Idaho banning transgender student athletes from female sports teams at public schools including universities, a contentious ‌issue enmeshed in the nation's culture wars.

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Jun 30 • 6:12 AM EDT • Sports • reuters.com
Nintendo Switch 2 Owners Face a New Hardware Lottery, as Upgraded LCD Revision Could Split Buyers Into Winners and Losers

A new Nintendo Switch 2 LCD panel leak points to a hardware revision potentially fixing the handheld's ghosting issues.

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Jun 30 • 5:27 AM EDT • Technology • wccftech.com
Lawsuit accuses businessman behind unfinished entertainment venue in Bryan of diverting company funds

The Schulman’s Movie Bowl Grille at Midtown Park is years behind schedule, and its owner is facing other legal issues, KBTX has learned

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Jun 29 • 10:44 PM EDT • Entertainment • kbtx.com
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Blackhawks Extend Qualifying Offers To Bedard & Three Other RFAs

Ahead of Monday’s 4:00 p.m. (CT) deadline, the Chicago Blackhawks issued qualifying offers to four of their six pending restricted […] The post Blackhawks Extend Qualifying Offers To Bedard & Three Other RFAs appeared first on Chicago Hockey Now.

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Jun 29 • 8:34 PM EDT • Sports • sports.yahoo.com
iOS 26.5.2 has fixes for 25+ security issues on iPhone, details here

Today Apple released its latest iPhone software update, iOS 26.5.2, which includes fixes for nearly 30 security issues. Here are the details.

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Jun 29 • 2:27 PM EDT • Technology • 9to5mac.com
LeBron Reportedly Issues 'Ultimatum' To Warriors Amid Free Agency Rumors

LeBron James has reportedly issued an "ultimatum" to the Golden State Warriors amid the ongoing free agency rumors. The four-time NBA champion forward is set to hit free agency this summer. LeBron is most likely to return to the Lakers, though another team could be inching closer and closer. The ...

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Jun 29 • 2:27 PM EDT • Sports • sports.yahoo.com
Issues & Ale: It's Just Politics - Michigan’s Primary Election Preview (Jul. 29, 2026)

Join Michigan Public’s "It's Just Politics" co-hosts Zoe Clark and Rick Pluta and their guest panel of political experts for a preview of the upcoming Michigan Primary, less than a week before the election!

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Jun 29 • 1:15 PM EDT • Politics • michiganpublic.org
Cook County Issues New Funding Opportunities to Improve Mental Health in Suburban Cook County - Cook County Department of Public Health

Cook County Department of Public Health has issued an open call for funding opportunities to help improve mental health in suburban Cook County. The funding opportunities reflect the department’s commitment to building healthier communities in suburban Cook County. The open calls are for restorative practices in schools and power building.

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Jun 29 • 11:43 AM EDT • Health • cookcountypublichealth.org
Maresca controversy grows as Manchester City and Chelsea trade statements

Manchester City have issued a counter-statement to Chelsea, as the controversy continues to grow over how and when they approached Italian Enzo Maresca, prompting a €20m compensation package.It was ...

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Jun 29 • 11:20 AM EDT • Sports • sports.yahoo.com
Supreme Court rejects legal battle over New York's COVID-19 vaccine mandate for healthcare workers

The dispute arose after New York's Department of Health issued an emergency rule that required healthcare workers to be fully vaccinated against COVID-19.

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Jun 29 • 9:52 AM EDT • Health • cbsnews.com
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Supreme Court issues opinions

Major rulings are anticipated this week in cases involving presidential power, birthright citizenship and transgender rights.

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Jun 29 • 9:18 AM EDT • Politics • cnn.com
OpenAI sets up 'warroom' to fix Codex limit issues

OpenAI investigates Codex's usage limit depletion that's impacting some users. The company has reset user caps to address the problem.

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Jun 29 • 8:51 AM EDT • Business • businessinsider.com
Xbox Announces 'Record' Pre-Orders For GTA 6 In Response To New Report

A rare statement has been issued

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Jun 29 • 6:00 AM EDT • Technology • purexbox.com
This Ochsner Health “intrapreneur” has tips for innovating in-house

Korak Sarkar, MD, MHDS, leads a biodesign lab at Ochsner Health and details how physicians can pursue innovation from within their organizations.

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Jun 29 • 3:00 AM EDT • Health • ama-assn.org
Who slept worst last night: Valtteri Bottas

The Finn had a rough weekend in Austria, battling reliability issues that echoed the fortunes of backmarkers of old

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Jun 29 • 1:47 AM EDT • Sports • sports.yahoo.com
AHA/ACC/ESC/WHF Expert Consensus Document in Collaboration with HFSA, HFA and JHFS: Second Universal Definition of Heart Failure (2026)

In response to the rising global prevalence of heart failure (HF) and limitations in research, surveillance, and prevention, in 2021 multiple cardiac societies convened to issue the First Universal Definition of Heart Failure, establishing uniform terminology, including a designated Stage B (pre-HF) to identify at-risk individuals.

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Jun 28 • 8:00 PM EDT • Science • professional.heart.org
These fat-filled brain cells may be making multiple sclerosis worse

Scientists have uncovered a surprising clue that may help explain why multiple sclerosis (MS) progresses rapidly in some people but not others. In brain tissue from patients with severe MS, researchers found large numbers of “foamy” immune cells packed with fat droplets after absorbing damaged myelin. These overloaded cells appear to switch from helping repair the brain to fueling ongoing damage and inflammation.

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Jun 28 • 8:00 PM EDT • Science • sciencedaily.com
Meaningful Outcomes Determine the Winners of the Health AI Race

Global investment in healthcare AI exceeded $18 billion in 2025, yet health systems still lack a shared understanding of the outcomes that investment should deliver. This paper argues that success in the health AI race will be determined not by technological sophistication but by which systems first identify and pursue the outcomes that matter most to patients, professionals and health systems. Without a shared language for defining and measuring what healthcare AI should deliver, systems risk optimizing for what is easiest to count rather than what matters most. This paper provides a framework for ensuring AI investment translates into real value for healthcare systems and the populations they serve.

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Jun 28 • 8:00 PM EDT • Health • weforum.org
Scientists Discover Ultrasound May Stop Arthritis Before It Starts

A new study suggests low-intensity ultrasound can influence immune cell behavior in ways that may reduce chronic inflammation and encourage tissue repair after joint injury.

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Jun 28 • 6:11 PM EDT • Science • scitechdaily.com
Prediction market Kalshi sues Illinois over its push to regulate sports bets

The most recent move in the ongoing legal battle between the state and prediction market operators came after the state enacted new sports wagering taxes to support the $55.9 billion budget it passed this spring.

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Jun 28 • 5:14 PM EDT • Sports • kwqc.com
Laredo Public Health issues summer food, pool safety reminders

Laredo Public Health is reminding residents of food and pool safety steps as warmer weather increases the risk of foodborne illness.

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Jun 28 • 5:01 PM EDT • Health • kgns.tv
Multiple Portland-area mental health crisis lines down due to technical outage

Mental health crisis lines in Multnomah, Washington, and Clackamas counties are down due to technical issues, and officials are urging people to call or text 988 if they or someone they know is exp…

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Jun 28 • 3:38 PM EDT • Health • koin.com
Royals' Jac Caglianone: Managing groin issue

Royals' Jac Caglianone: Managing groin issue

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Jun 28 • 12:10 PM EDT • Sports • cbssports.com
Los Alamos Faith And Science Forum Announces Schedule Of Lectures Through Aug. 12

Courtesy image/LAFSF Los Alamos Faith and Science Forum News: For 2026, the Los Alamos Faith and Science Forum invites the public to examine issues at the interface of faith and science on Wednesdays through Aug. 12. After a light dinner at 6 p.m., presentations will begin at 6:30 p.m. to be followed by a Q […]

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Jun 28 • 12:05 PM EDT • Science • ladailypost.com
The Top 5 Iconic and Valuable Graded Baseball Magazines

Graded baseball magazines have become one of the hobby's fastest-growing collectibles. Here are the five issues every collector should know.

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Jun 28 • 10:25 AM EDT • Sports • sports.yahoo.com
6 Ways Your Body Can Change After Starting a High-Protein Diet

Adding more protein to your diet can cause several changes in your body, such as better muscle repair and potential digestive issues.

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Jun 28 • 8:00 AM EDT • Health • health.com
Prescott, Parker present Cowboys with an 'iron sharpens iron' dynamic

Cowboys quarterback Dak Prescott has had issues solving two defensive schemes. With Christian Parker in the building, he may finally figure it out.

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Jun 28 • 7:00 AM EDT • Sports • sports.yahoo.com
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UVA Health finding continuing issues with counterfeit child safety seats in vehicles

It's buyer-beware as it's not illegal to sell FMVSS non-compliant seats

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Jun 28 • 6:45 AM EDT • Health • cvillerightnow.com
Americans now live longer in Democratic-held House districts. Here’s why

Even as health care issues rise in the 2026 campaign debate, new data show that far more House Republicans than Democrats represent districts where the most residents face major medical challenges — and lack health insurance.

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Jun 28 • 6:30 AM EDT • Health • cnn.com
Report: Astros to Call Up RP Miguel Ullola

The Houston Astros are calling up pitching prospect Miguel Ullola, according to a report from Chandler Rome of The Athletic. Ullola, 24, is ranked as the Astros #11 prospect per MLB.com. Ullola was converted to a reliever this season in an effort to help him with his command issues and be someone the team could […]

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Jun 27 • 7:33 PM EDT • Sports • sports.yahoo.com
GOP candidate with same name as senator can stay on Alaska ballot, judge rules

Supporters of incumbent Republican Sen. Dan Sullivan say a challenger with the same name is not running in “good faith,” but a judge says that is not an issue.

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Jun 27 • 4:39 PM EDT • Politics • washingtonpost.com
Nintendo issues June 2026 backwards compatibility fixes for Switch games on Switch 2, full list

Another set of backwards compatibility fixes for Nintendo Switch games on Switch 2 are now available. There aren’t as many heavy hitters this time around, but it’s still a solid batch. Shovel Knight: Treasure Trove is the biggest name out of the bunch – previously, Nintendo said that players may encounter audio issues in some areas. The full list of...

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Jun 27 • 4:26 PM EDT • Technology • nintendoeverything.com
New vitamin B12 therapy shows promise against deadly brain cancer

Researchers have identified a vitamin B12–based compound that can cross the blood-brain barrier and home in on glioblastoma tumors. In animal studies, the compound accumulated preferentially in tumor tissue and delivered sustained nitric oxide directly to cancer cells. It also worked synergistically with existing glioblastoma treatments, significantly enhancing their tumor-fighting effects.

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Jun 27 • 8:00 AM EDT • Science • sciencedaily.com
Prediction market Kalshi sues Illinois over its push to regulate sports bets

Prediction market Kalshi — which offers trades on everything from the World Cup top goalscorers to the winners of the reality show Love Island and the 2028 Democratic primary — sued Illinois on Tuesday over its latest push to regulate sports bets on the platform.

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Jun 27 • 7:51 AM EDT • Sports • wifr.com
Colorado Politics Calendar June 29-July 5

CoPo’s weekly political calendar will help you find political and public-policy events throughout Colorado. It includes candidate and issue campaign events, public policy meetings, court hearings, state and local party conventions, assemblies, debates, rallies, parades, speaking engagements, traveling dignitary appearances, water meetings, book signings, county commission hearings, city council meetings and more. As a subscriber, […]

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Jun 27 • 7:09 AM EDT • Politics • coloradopolitics.com
49ers News: Gotta let the Bosa Brothers dream go…

Adam Schefter believes Joey Bosa has played his last down in the NFL“Bosa turns 31 in July. Last year was the first time he appeared in double-digit games since 2021. The 49ers would pursue an edge rusher if Nick or Mykel Williams are behind the 8-ball on their rehab. Some believe Mykel begins the season […]

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Jun 27 • 5:00 AM EDT • Sports • sports.yahoo.com
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Prediction market Kalshi sues Illinois over its push to regulate sports bets

Prediction market Kalshi sued Illinois on Tuesday, seeking to block new taxes and license requirements set to take effect July 1.

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Jun 26 • 7:25 PM EDT • Sports • cbsnews.com
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Prediction market Kalshi sues Illinois over its push to regulate sports bets

Suit seeks to block new taxes and licensing requirements set for July 1

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Jun 26 • 5:19 PM EDT • Sports • nprillinois.org
Prediction market Kalshi sues Illinois over its push to regulate sports bets

Article Summary Prediction market Kalshi sued Illinois on Tuesday, seeking to block new taxes and license requirements set to take

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Jun 26 • 4:23 PM EDT • Sports • capitolnewsillinois.com
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Public health alert issued for chicken sold at popular grocery store in the Tri-State area

A public health alert was issued for chicken sold at a popular grocery store chain in the Tri-State area.

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Jun 26 • 3:59 PM EDT • Health • local12.com
Axios Live: Health care affordability emerges as a defining issue

Concerns about health care costs are motivating voters across the ideological spectrum

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Jun 26 • 3:19 PM EDT • Health • axios.com
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Congress subpoenas Leon Black during interview about Jeffrey Epstein

The House Oversight Committee issued subpoenas to billionaire Leon Black after he declined to answer questions about non-disclosure agreements.

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Jun 26 • 2:33 PM EDT • Business • businessinsider.com
Rock Creek Entertainment District under siege in new lawsuit

A citizens group has sued to block Norman's $1.1 billion Rock Creek Entertainment District, alleging constitutional and Open Meetings Act violations.

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Jun 26 • 1:11 PM EDT • Entertainment • journalrecord.com
As Pa. measles outbreak worsens, state health official issue strong call to action: 'We are not just sitting back and watching this virus spread'

LANCASTER, Pa. — State Health Secretary Debra Bogen on Friday issued a strong call to action in the wake of a measles outbreak not seen in Pennsylvania...

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Jun 26 • 1:01 PM EDT • Health • post-gazette.com
Sheriff’s office releases body-cam video after viral arrest at Augusta business

The Richmond County Sheriff’s Office has issued a statement after a video has been circulating social media of a woman’s arrest.

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Jun 26 • 11:41 AM EDT • Business • wrdw.com
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DJ and presenter Trevor Nelson taking a break from work due to health issues

The Radio 2 presenter said he was now "concentrating on getting better".

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Jun 26 • 4:40 AM EDT • Health • bbc.com
Real Madrid’s summer spending spree creates unexpected Champions League problem

Real Madrid have been one of the busiest clubs in the transfer market, but their impressive recruitment spree may have created a technical issue.Notably, Jose Mourinho has already welcomed four new si...

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Jun 26 • 3:40 AM EDT • Sports • sports.yahoo.com
Strategy Of Employing AI Mental Health Chatbots As School Psych Counselors For Teens

Teens increasingly have mental health issues, schools are trying to keep up. School psychologists are costly. LLMs can be an amplifier as a tool. An AI Insider scoop.

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Jun 26 • 3:15 AM EDT • Health • forbes.com
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Thieves are breaking through drywall to burglarize Chicago businesses, police warn

Chicago police issued a community alert on Thursday warning that several businesses have been burglarized by thieves who broke in through the drywall.

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Jun 25 • 10:38 PM EDT • Business • nbcchicago.com
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Trump's DOT clears a pedal-free path for Tesla and Zoox

The NHTSA is proposing allowing the removal of pedals and steering wheels for AVs, making it easier for Tesla and Zoox to pursue alternative designs.

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Jun 25 • 9:07 PM EDT • Business • businessinsider.com
It's Xbox's turn (again), as console prices keep going up

Microsoft announced a price hike for the Xbox Series consoles today, the third in little over a year. Effective August 1, the Xbox Series S, which launched in 2020 for $300, will cost $500 in the U.S. The Xbox Series X, which launched in 2020 at $500, will go for $800. This follows a round of PlayStation 5 price increases from Sony this spring, and a slow-motion increase for Nintendo’s Switch 2, which will kick in in the U.S. in September. (Mind you, there were also eight video game industry price hikes in six months of 2025). The chart up top shows the sudden ascent of console prices over the past year, a sudden surge in an already unusual hardware generation. Prices had been flat for years, now “up” is the new “flat.” Game console prices used to go down across the length of a console generation, but not this time around. Microsoft’s explanation for the new price hike today: We hoped another price increase would not be necessary, and we have spent the last several months working with suppliers on options. Unfortunately, console storage and memory prices have increased by more than 2.5x and we expect another doubling by the fall of 2027. The entire consumer electronics industry is struggling with the current components crisis, but the effects are particularly hard on consoles. Unlike phones, computers, speakers, and other consumer devices, consoles are typically not sold at a profit, but instead for less than they cost to make. This is an issue well beyond game consoles. Apple announced price hikes on its computers and tablets today as well. Game File is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe Item 2: Brutal Bungie cuts Bungie laid off “most” of its Destiny development team and some developers who worked on Marathon, the newest game from the struggling Sony-owned studio. A WARN notice issued by Sony to Washington State, where Bungie is based, tallied cuts impacting 292 workers, effective next month. That’s strictly for Bungie/Sony jobs in Washington and wouldn’t account for any elsewhere. The video I clipped below shows the redacted list of Bungie cuts filed to Washington State officials. As you’ll see, I had to scroll for a while… In a note emailed to PlayStation workers and published online, PlayStation game studios chief Hermen Hulst offered the following explanation for these latest cuts at Bungie: This is painful news, especially for talented colleagues whose roles have been eliminated. This decision was made only after extensive discussion and careful consideration, and I want to provide some context on how we arrived here. Over the past several months, together with Bungie leadership, we reviewed the studio’s long-term direction, development priorities, resource needs, and role within our broader portfolio strategy. We explored multiple alternatives before concluding that a reduction was necessary to align the studio’s resources with its current priorities and long-term goals. In 2022, Sony bought Bungie for $3.7 billion. The studio’s marquee game, the multiplayer live service shooter Destiny 2 was losing popularity at the time. Its next game Marathon, released earlier this year, has been well-reviewed but had a slow start. Bungie is renowned for making great shooter games, and Destiny fans have mourned the wind-down of Destiny 2. They’ve also expressed bewilderment over reports that Destiny 3 is not, per Bloomberg, immediately in the cards.

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Jun 25 • 8:21 PM EDT • Technology • gamefile.news
Trump likely to ‘lose’ on birthright citizenship case, political analyst says

Fox News senior political analyst Juan Williams discusses the Supreme Court set to issue a ruling on birthright citizenship on ‘Special Report.’

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Jun 25 • 8:09 PM EDT • Politics • foxnews.com
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Discussing progress in nuclear fuel and materials science

The NEA held the sixth annual week of collaborative meetings of the Working Party on Materials Science Issues in Nuclear Fuels and Structural Materials (WPFM) from 18-22 May 2026 at the NEA offices in Boulogne-Billancourt, France.

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Jun 25 • 8:00 PM EDT • Science • oecd-nea.org
Dolly Parton makes surprise appearance — complete with a joke

Dolly Parton just made a surprise appearance, complete with her trademark humor, amid health issues.

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Jun 25 • 6:58 PM EDT • Entertainment • ew.com
Ex-NFL player Doug Martin's family sue Oakland police, allege restraint asphyxia in fatal mental health crisis

Parents of former NFL running back Doug Martin file wrongful death lawsuit alleging he died from restraint asphyxia caused by Oakland police.

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Jun 25 • 6:22 PM EDT • Health • foxnews.com
Making Our Own Luck

We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.

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Jun 25 • 4:48 PM EDT • Science • goodscience.substack.com
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Dolly Parton surprises fans at opening of her new travel stop amid ongoing health battle

Parton had to cancel her Las Vegas residency after announcing she was being treated for an undisclosed health issue.

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Jun 25 • 3:30 PM EDT • Health • komonews.com
Consumer Discretionary Stocks Drawing Institutional Rotation Into Live Entertainment Leaders

With the Federal Reserve hinting at a pause in rate hikes, stubborn inflation still in the background, and several large companies surprising on earnings, consumer discretionary stocks are back in focus for investors weighing risk and opportunity. This article looks at how that mix of easier policy signals, solid corporate reports, and ongoing geopolitical and supply chain issues could affect larger U.S. consumer-focused companies. It will walk through 3 stocks from a curated screener that...

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Jun 25 • 2:20 PM EDT • Entertainment • simplywall.st
Platner, Collins’ campaign spar over federal contracts

Platner released a multi-point plan he calls “a corruption crackdown,” which covers issues such as big money in politics, lobbying activities by former members of Congress, and making it more difficult for presidents to cash in on their position while in office.

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Jun 25 • 2:04 PM EDT • Politics • spectrumlocalnews.com
Samsung Reportedly Starts OLED Panel Production for Apple’s First Foldable iPhone

Apple reportedly cleared Samsung Display to make OLED panels for its first foldable iPhone, with hinge issues still shaping launch timing.

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Jun 25 • 1:13 PM EDT • Technology • techrepublic.com
Poppi founder speaks about building a billion-dollar soda business

Allison Ellsworth, the founder of the viral soda brand Poppi, sits down with NBC News' Savannah Sellers to discuss how she turned a personal health issue into a billion-dollar cultural phenomenon.

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Jun 25 • 11:26 AM EDT • Business • nbcnews.com
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Longtime Entertainment Industry Lawyer Joins Royalties Retriever SoundExchange

Michele Page, formerly of Peloton Interactive, arrives at a pivotal time for the nonprofit reeling from a court ruling that may impair its ability to sue on behalf of artists.

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Jun 25 • 11:13 AM EDT • Entertainment • law.com
Another look at carrots and eyesight; how to get more fiber; why mosquitoes bite some people and not others; plus other stories with Vanderbilt Health sources

AARP reporter Stacey Colino interviewed Milam Brantley, MD, Associate Professor of Ophthalmology and Visual Sciences, in 2020 for a story about whether eating carrots can improve vision. Sacramento Bee reporter Samantha Agate has now used Brantley’s comments in an AI-curated story created by content specialists on the same topic that has been picked up by MSN and others. Prevention magazine interviewed Heidi Silver, RD, PhD, Founding Director of the Vanderbilt Diet, Body Composition, and Human Metabolism Core, for a story about the importance of fiber and how people can get more of it in their diet. William Schaffner, MD, Professor of Preventive Medicine, was quoted by several news outlets about public health issues, including: Women’s Health (tick bites and alpha-gal syndrome); The Washington Post (tetanus); and Healthline (why mosquitoes prefer to bite some people and leave others alone). A visit to Monroe Carell Jr. Children’s Hospital at Vanderbilt by some Banana Ball baseball players was covered by The Tennessean and WZTV Fox 17 News, and The Tennessean’s story was also picked up by Yahoo! Sports. Clarksville Now published a story written by the Montgomery County Economic Development Team, whointerviewed Bradley Stancombe, MD, professor of Clinical Pediatrics, Vanderbilt Neonatology, about the new energy of Vanderbilt Clarksville Hospital and how the facility is recruiting physicians. Healio Allergy/Asthma group editorial director Richard Gawel interviewed Mark Rolfsen, MD, Clinical Fellow in the Division of Allergy, Pulmonary and Critical Care Medicine, for a story about his presentation at the American Thoracic Society meeting on metal health outcomes following ICU discharge. Nashville Scene reporter Hannah Herner interviewed James Crowe, MD, Director of the Vanderbilt Center for Antibody Therapeutics, for a story about his efforts to prepare for the next pandemic by isolating antibodies that can neutralize dangerous viruses. Medscape reporter Kathleen Doheny interviewed Neesha Choma, Associate Chief of Staff of Vanderbilt University Hospital, for a story about how hospitals can reduce readmissions.

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Jun 25 • 10:56 AM EDT • Health • news.vumc.org
Supreme Court protects pesticides from some health claims in key Roundup case

The Supreme Court on Thursday restricted Americans’ ability to sue pesticide makers over alleged health harms stemming from their products. In a 7-2 ruling, the court held that some claims that pes…

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Jun 25 • 10:11 AM EDT • Health • thehill.com
Lionel Richie cuts concert short over health issue after sitting down mid-performance

"What I have learned about my years of being in the business. When you are feeling dizzy, sit your ass down," Richie told the crowd.

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Jun 25 • 8:50 AM EDT • Entertainment • yahoo.com
Dolly Parton Makes Surprise Appearance Following Health Issues

Dolly Parton made a surprise appearance at the grand opening of her travel stop in Tennessee just one month after she canceled an upcoming Vegas residency due to health concerns.

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Jun 25 • 8:15 AM EDT • Health • today.com
FDA-approved drug may finally help immunotherapy defeat rare liver cancer

Researchers found that a rare liver cancer evades immunotherapy by luring immune T cells away from the tumor and trapping them in nearby fibrous tissue. An FDA-approved drug called AMD3100 freed those T cells to attack the cancer, significantly improving the effectiveness of immunotherapy in tumor samples.

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Jun 25 • 8:00 AM EDT • Science • sciencedaily.com
I couldn't find a job, so I'm going to nursing school at 45

A 45-year-old couldn't find a corporate job for over a year so she decided to pursue nursing school instead. She wishes she started sooner.

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Jun 25 • 5:14 AM EDT • Business • businessinsider.com
Union issues spark conflict between Group Health Co-op and members

Changes in the Group Health bylaws have become a point of contention for members who say they are ignored by the co-op's management,

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Jun 25 • 4:30 AM EDT • Health • wisconsinexaminer.com
Can Bardella learn the Meloni method?

Also, in Thursday’s edition: Spain sues Commission, EEAS sec gen, Taliban

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Jun 25 • 2:36 AM EDT • Politics • euractiv.com