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Salsa classes seek to spread Hispanic culture, boost campus life
The free weekly dance classes are at 1 p.m. Thursday in the Science and Engineering Innovation and Research Building.
Upcoming Trump rally at Freeman Coliseum draws mixed reaction from San Antonio voters
Free Finance Fair planned at Santa Fe Business Incubator
The free event will be held from 8:30 to 10 a.m. Thursday at the Santa Fe Business Incubator.
John E. Sununu pressed on loyalty to Trump in Nashua forum
John E. Sununu pointed to his bipartisan approach to politics during his previous stretch in Congress while answering voter questions in Nashua on Monday.
Young people harassing local businesses, prompting request from Carnegie police
Trump says his super PAC will start paying for controversial taxpayer-funded ads
The science behind the Superdome’s roar during the Domecoming game
Superdome Decibels Debunked: How loud was the Dome when Steve Gleason blocked the punt?
A Florida university focuses on space medicine to train future astronaut healthcare providers
A university is expanding its space medicine program to train future physicians to care for astronauts before, during, and after space missions.
The Harvard Crimson (@theharvardcrimson)
24 likes, 0 comments - theharvardcrimson on October 5, 2026: "Caroline B. Kennedy ’80 introduced the Institute of Politics’ 60th anniversary forum Thursday, marking her first known public appearance at the Institute since she resigned from its Senior Advisory Committee more than six years ago. Kennedy — the daughter of President John F. Kennedy ’40, to whom the IOP is dedicated – stepped down as the committee’s honorary chair in 2020 amid concerns over the IOP’s diminished independence, declining programming, and tensions with Harvard Kennedy School leadership. Full story linked in bio. 🖋: Jen L. Phan and Mirei S. Saneyoshi 📷: Grace E. Yoon".
Angela Paxton’s political ad draws attention amid Ken Paxton divorce
WVU Medicine officially absorbs Independence Health System, welcomes new employees
Oct. 8 talk to discuss building a new era of materials characterization
Pinshane Y. Huang, Racheff Faculty Scholar in the Department of Materials Science and Engineering at the University of Illinois, Urbana-Champaign, will give the talk “Building a new era of atom-by-atom materials characterization with electron ptychography” at 3:05 p.m. on Thursday, Oct. 8, in 10 Sparks Building on the University Park campus.
Tony Gilroy on Leaving the Politics of 'Andor' Behind for His 9-Composer Music Drama 'Behemoth!'
NEW YORK (AP) — Long before Tony Gilroy wrote “The Bourne Identity," made “Michael Clayton” or created “Andor,” he wanted to be a musician. After playing guitar in a string of bands, Gilroy came to Los Angeles hoping to become a studio musician. A session with some real players quickly disabused him ...
Fall Preview with Entertainment Correspondent Mike Marra
Airdate: October 5th, 2026 Leoni Township Update with Administrator Mike JesterOctober 5, 2026City Treasurer Hosting Town Hall Meeting SeriesOctober 5, 2026Tecumseh Appleumpkin Festival This WeekendOctober 5, 2026Fall Preview with Entertainment Correspondent Mike MarraOctober 5, 2026Disney’s Frozen Premieres Thursday at The SaukOctober 5, 2026Alison McGlynn & Lilly Hayworth, The Annex Collective SalonOctober 5, 2026John Spink, Nite…
Classic Chronicle: Norwich, Vermont, showcases sustainability and hands-on science
A 2006 Classic Chronicle explores how Norwich, Vermont, embraces sustainable living and interactive science education
Why I Don’t Think Ride Or Die Should Have Been Cancelled (And What Company Should Save It...)
(Welcome to my weekly streaming ratings report, the single best guide to what’s popular in streaming TV and what isn’t. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. If you were forwarded this email, please subscribe to get these insights each week.) So…I recently came across a Reddit thread, talking about films on streaming, wondering why there are no reliable sources out there for streaming ratings data. Sigh. Honestly, as annoyed as I am that so many still don’t realize that we have streaming ratings, I somewhat get it. Until now, there was such a long delay between when a show or film came to streaming and when we got its viewership data; I understand why people were confused. (But, as you know, this just changed.) Also, even back in the day, how many people knew how well films did on television? Luckily, as a reader, you’re in the know. Okay, on to this week’s issue. I want to take a look at Prime Video cancelling Ride or Die and whether I agree with that decision. Overall, we didn’t have any breakout hits (no TV shows landed over 20 million hours according to Nielsen) but we have a lot of steady performers on the streaming charts. Plus, we’ll look at where $50 million in missing box office dollars went. (Spoiler: straight-to-streaming.) All that, plus new episodes of The Secret Lives of Mormon Wives, Supergirl heads to streaming, a new YA show does well on Netflix, the viewership for the Daily Wire’s $50 million fantasy show, what TV show hit-maker can’t make streaming hits, CD sales, all the flops, bombs and misses, and a whole lot more. Let’s dive right in! (Reminder: The streaming ratings report focuses on the U.S. market and compiles data from Nielsen’s weekly top ten viewership ranks, Luminate’s Top Ten Data, JustWatch and Reelgood interest data, Samba TV household viewership, company datecdotes, Netflix hours viewed data, Google Trends, and IMDb to determine the most popular content. While most data points are current, Nielsen’s data covers the weeks of September 7th to September 13th, 2026. You can find a link to my terminology here.) Subscribe Television - Ride or Die Is a Hit…But It Got Cancelled? What The Data “Says” I hate the phrase “here’s what the data says”, even though sometimes I find myself using it. If data just told us everything, we data folks would be out of a job! Data is often messy, complicated and nuanced. When it comes to strategy, many of the best decisions can’t actually use “data”, since it’s vastly too complicated to model. Anyways, I’ve been singing the praises of Prime Video’s Ride Or Die this summer, a show that did very well for them. And yet…it got cancelled. Now, usually when a show gets cancelled, a bunch of websites say “a hit show got cancelled”... Here’s the thing, though: in this case, they’re right! The data “says” that this show was a hit. Specifically, out of 522 first seasons to make a week on the Nielsen charts since 2020, it’s the 75th biggest. On Amazon, Ride or Die is eighth out of 41 first seasons: That’s top 15th percentile all time, almost exactly, which is my definition of a “hit”! I mean, outside of Reacher, Amazon needed a hit this summer! (Admittedly, Off Campus did well for Amazon in the spring, but Ride or Die performed even better.) So what happened? Why did Amazon cancel one of their rare 2026 bright spots? Well, Deadline reported a reason—which I’ll get to—but I’d break it down into three relevant questions: What is a given streamer’s reasoning? Is that reasoning sound? Could the stated reason not be the real reason? According to Deadline, Amazon felt the show “over-indexed” in middle-aged women. (This was based on leaks from within Amazon.) The logic is this: Amazon already reaches this demographic because of unlimited two-day shipping bundled with Prime, so they don’t really need more shows like this. Now, it’s my job to ask if that’s a good reason, and I’ll be honest, in this case, I don’t think it is. Sure, this show may “over-index” in middle-aged women—I’ll just assume that’s the case here—but I think folks often oversell how important over-indexing actually is. When a show is a “hit”, it isn’t a bit bigger than its rivals; it’s usually multiples bigger. For example, Elle only made the charts for two weeks at 8.3 million hours each. So Ride or Die was 80% bigger in its first two weeks, and likely had a much stronger hold, with its terrific 13 million hours in week three. Ride or Die was nearly three times bigger than Sterling Point through three weeks too. And that means that _Elle, Sterling Point a_nd other Amazon YA shows need to not just over-index a little with younger women (assuming that’s who Amazon prefers over middle-aged women), but massively over-index. Otherwise, more people in that demo (and a bunch more besides) likely watched Ride or Die. (I’ll try to explore this concept more in a future article.) And don’t get me started on how Ride or Die did compared to a certain (very, very popular, possibly the world’s most popular) YouTuber’s reality show…which didn’t make the charts after its first week and likely cost much, much more than Ride or Die. All to say, Amazon-MGM Studios/Prime Video can tell reporters that this show didn’t reach the right audience, but that excuse feels weak to me. So this leads to the third question: could other reasons have come into play? Yes! Renewal or cancellation decisions rarely (I’m tempted to say “never”) boil down to one variable. At its simplest, it’s two things: budget versus viewership. But often factors like critical acclaim, ownership and, yes, personal opinion come into play. In this case, Amazon has a new executive running things, and this show isn’t owned by Amazon-MGM Studios (unlike Elle). And yes, it may not have indexed with the right target viewers, too. Likely all of those factors came into play.1 My guess is ownership ended up mattering most. Amazon doesn’t own Ride or Die. It’s actually produced by another major studio. Fortunately/allegedly, this show is being shopped around. I can think of one brand new CEO who should consider it for one of his two major streamers…especially if he wants to rebuild goodwill in Hollywood. His name is on this list of exec producers of Ride or Die… If David Ellison needs some goodwill—and he does—rescue this female-led show tomorrow and grab some good headlines for a day. The data justifies it. Quick Notes on TV We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… How The Secret Lives of Mormon Wives latest season did on Hulu, post-controversy... Whether Supergirl soared on HBO Max... Why the box office is losing money due to the streamers... The viewership for the Daily Wire’s $50 million fantasy show... Updates on The Gentlemen, Lanterns, Outer Banks, King of the Hill and more... What former hit-maker has three streaming flops in a row... Whether The Mandalorian and Grogu popped in week two... All the flops, bombs and misses... And a whole lot more... ...please subscribe! We can only keep doing this great work with your support. If you want an idea of just how much content you’d get in a full issue, check out this older issue. Coming Soon! Oh man, we’re almost caught up! We just have two more issues, then the streaming Ratings Report will be coming out just two weeks after a TV show premieres! Next issue, I’ll be looking at the first two weeks of the NFL Thursday night games on streaming, a huge new spinoff, Reacher’s Neagly on Prime Video, and the latest edition of Monster: The Lizzie Borden Story on Netflix, the return of Slow Horses on Apple and MobLand (quietly one of their biggest shows) on Paramount+, and Dancing with the Stars on both ABC and Disney+. Plus I’ll take a look at animation for adults in 2026. The week after, a ton of movies are coming to streaming: Toy Story 5 on Disney+, Backrooms on HBO Max, Jackass: Best and Last on Paramount+ and The Breadwinner on Netflix, plus a Unabomber film on Netflix and a romcom on Prime Video. Woody Harrelson and Matthew McConaughey have a show on Apple, along with a game show inspired by Willy Wonka that everyone seems to hate. Long term, some crazy (but hopefully crazy like a fox) IP news. FX ordered a new Sons of Anarchy show from Charlie Hunnam, but it’s not about the biker gang. No, it features the show’s cast playing themselves in a new “meta-thriller”. Huh. And a lot of the cast is coming back. Next, Ryan Gosling is producing a Flintstones movie about a “grown-up Bamm-Bamm Rubble”. Also, huh. This one is in “early development” so we’ll see what happens. Both projects are based on IP, but also seem to have crazy takes on the IP, which I like.
5 faith-filled, family-friendly movies streaming this fall
For viewers looking for faith-filled and family-friendly entertainment as the weather cools down, here are five films making their way to streaming platforms, with stories of faith and courage
OSU Center for Health Sciences raises more than $800K for wellness center, scholarships
Oklahoma State University Center for Health Sciences hosted its first Orange Impact event Thursday and raised more than $800,000 toward a new wellness center an
Sphere Entertainment Sinks 12% on Analyst Downgrade: Demand “Softening Faster Than Expected”
Sphere’s own ticket-sales milestones show the same slowdown the analyst sees
Police urge Pennsylvania businesses to remove skill games as legal deadline approaches
Months after a justice ruled that skill games are legally slot machines, a deadline is fast approaching for the machines to be removed.
Final Family Health Festival of the year comes to Reno-Sparks Livestock Events Center Pavilion
The final Family Health Festival of the year takes place Thursday, Oct. 8.
Small Business Report
Provided by Prince William County Development Services In August, 19 small business owners received a certificate of occupancy or written authorization to ‘Open for Business’ from Prince William County DepartmentRead More
Doctors Should Keep an Eye on Your Mix of Medication. If They Don’t, You Should.
By Paula Span | KFF Health News Medications can snowball as we age. Pill organizers pile up. Prescriptions that are no longer necessary can mix with other drugs to create concerning side effects. “Once you get to six or seven prescription medications, you get a nearly 100% chance of some sort of ...
Hello from Seattle: XBOX FanFest Comes Home November 12
Seattle, we’re coming home. XBOX FanFest is coming on Thursday, November 12, 2026 - find out what to expect and how to attend inside.
Minneapolis man sentenced to 5 years in prison for string of business burglaries
Former ‘American Idol’ singer Caleb Flynn awaits sentencing for wife's murder
A former Ohio music pastor who appeared briefly on “American Idol” is set to be sentenced after a jury convicted him last week of murdering his wife while he was having an affair.
Former press secretary Karoline Leavitt lands her next gig: Fox News contributor
Former White House press secretary Karoline Leavitt is joining Fox News as an on-air contributor starting Nov. 1.
Seedy K’s Pigskin Palaver: House of Cards & Much Mo’
Ah yes, October; the pigskin campaign is morphing more fully developed. And, fully enveloping. This week, there’s a football game on every single night. Not just the more traditional Thursday, Friday, Saturday, Sunday, Monday. Because Draft Kings and Fan Duel and The World Wide Leader need content, we get Southern Miss and Troy on Tuesday, […]
Ceiling collapse causes neighboring business to close in Northern Colorado
Dennis Hastert, longtime Republican House speaker who went to prison, dies at age 84
Dennis Hastert, who served as House speaker longer than any other Republican but later was sent to prison in a hush-money case, has died.
Dennis Hastert, longtime Republican House speaker who went to prison, dies at age 84
Dennis Hastert, who served as House speaker longer than any other Republican but later was sent to prison in a hush-money case, has died.
Jeffries says House Democrats aiming to repeat 2018 sweep by flipping Trump districts
The Democratic Party is working to expand the map by going on offense in Republican-held districts, while President Donald Trump hits the trail in a red-state sprint to boost voter enthusiasm and shore up support from his base.
Do More Steps Mean Better Mental Health For Teens?
By HealthDay Staff HealthDay ReporterMONDAY, Oct. 5, 2026 (HealthDay News) — A teenager's daily step count may improve more than their physical health — it may also help protect their mental health. Researchers tracked more than 5,500 adolescents (average age: 12), using Fitbits, brain scans and ...
Eurozone business activity grows at fastest pace in 41 months in September
Private sector growth accelerates as demand improves, while input costs, selling prices rise at fastest rates since May | Anadolu
PEN America: Nearly 12,000 school book bans in a year, a record high
A new study from PEN America reveals that there were nearly 12,000 book bans in public schools over the past year, the highest since tracking began five years ago.
ACSH in the Media: Yahoo News, RealClear, Science & Culture, and More
From cancer and cannabis to perverse research incentives, we’ve been busy confronting nonsense. Here’s a roundup of recent media appearances and pickups featuring ACSH experts across the web, including coverage in Yahoo News, RealClearHealth, RealClearScience, and Science and Culture.
Pope Francis' diaries to be published next month, revealing reflections on Vatican years
Pope Francis' journal entries from his time in the Vatican and years before will be published this fall.
Ohio Democrats’ path to the governor’s office runs through rural areas that had turned against them
Democrats say their nominee for governor in Ohio, Dr. Amy Acton, represents the party’s best chance in years to win that office.
Ohio Democrats’ path to the governor’s office runs through rural areas that had turned against them
Democrats say their nominee for governor in Ohio, Dr. Amy Acton, represents the party’s best chance in years to win that office.
New TV shows to watch this week: Tune in to 'Cupertino' on CBS, stream 'Carrie' on Prime Video and revisit 'The Haunting of Hill House' on Netflix
The new TV shows worth watching — from the HBO divorce drama "War" to Netflix's "East of Eden" adaptation and a seaside mystery starring Josh Hartnett.
Kingdom Hearts I-III for Switch 2 should've been a slam dunk, but some games need more work
The inconsistent port quality and issues hold some of these KH games back on Switch 2. Square Enix should've done more.
$350 million Memorial Health project to bring road and parking changes
A $350 million Memorial Health project will add a 90-bed tower, cafeteria, loading dock and parking garage.
Yale School of Medicine On the Science of Childhood Anxiety, Say, Anxiety Disorders Are the Most Common Mental Health Challenges In Youth
Credit: Matt Bradbury October 5, 2026 - By Isabella Backman - Anxiety disorders are the most common mental health challenges in youth. Left untreated, they can disrupt the lives of both children and their families. The good news is that with intervention, most children will overcome these conditions. Across Yale School of Medicine, scientists are working to understand anxiety at every level, from common anxious behaviors to molecular biomarkers in the brain. They are using their findings to develop and disseminate new evidence-based treatments for childhood anxiety. Today, the go-to treatment for childhood anxiety disorders is cognitive behavioral therapy (CBT). This is a form of psychotherapy that teaches children skills for confronting anxious thoughts and helps them practice managing situations that cause anxiety. While it is the gold-standard treatment backed by considerable scientific evidence, up to 50% of children will not see sufficient benefit from CBT alone. Wendy Silverman, PhD, Alfred A. Messer Professor in the Child Study Center, co-directs the Anxiety and Mood Disorders Program alongside Eli Lebowitz, PhD, associate professor in the Child Study Center. One of their main interests is learning how to improve outcomes beyond CBT. “We’re developing cutting-edge, research-based knowledge that can reduce the suffering that anxiety causes children and their families,” says Silverman. Changing parent behavior YSM experts are investigating how to improve CBT outcomes for children by involving the parents. Silverman’s research has uncovered two main components of parent intervention that improve childhood anxiety: not enabling children to completely avoid the things that make them anxious and taking steps to enhance their autonomy. Parents may unintentionally reinforce their child’s anxiety by allowing them to avoid what makes them anxious. They also may unintentionally limit the children’s sense of autonomy by being overly intrusive. “One of the things that we take pride in is that we’ve focused on trying to understand what parents need to do, and to test our ideas and see if changing the parents’ behaviors is enhancing the effects of CBT,” Silverman says. “Our findings thus far suggest that they do." As much as CBT can be helpful, it can also be challenging to get one’s child to do the necessary steps for CBT to work. This is one important reason why Lebowitz created a novel intervention program for parents named Supportive Parenting for Anxious Childhood Emotions (SPACE). Existing intervention programs often teach parents to act as therapists for their child, such as training them on how to practice breathing exercises. “It makes sense, but this doesn’t work very well in practice,” says Lebowitz. “And part of the reason, I think, is that it’s not easy to get your kid to do things, especially if they’re not excited about doing it.” SPACE is unique because it focuses entirely on parent involvement and changing parental behavior—children are not involved in the sessions. For example, parents learn how to use supportive messages that convey confidence that their child can tolerate and manage distress. “It might sound like a parent saying to a child, ‘I get that this is really hard for you, but I know that you can handle it,’” Lebowitz says. The program also works with parents to identify the ways in which they are accommodating anxious behaviors. “We’ll pick one thing that parents are doing that is an accommodation and help them make a detailed plan for how they’re going to change that,” Lebowitz explains. Treating Anxiety in Children and Adolescents Much of the existing research on SPACE has focused on parents of children under age 14. Ongoing studies are now exploring its use with parents of older teens. “Both anxiety and accommodation can interfere with normative developmental shifts during the teen years, including increased autonomy and individuation from parents,” says Rebecca Etkin, PhD, associate research scientist in the Child Study Center. “In this sense, SPACE may be particularly well-suited for anxious teens and their parents. We want to see whether it is effective during this distinct developmental window.” Unfortunately, many families in need of CBT face barriers, including limited availability of services and geographic constraints. One way to improve access is digital interventions. Silverman and her team are developing an evidence-based digitized intervention program for parents that they can access directly from their computer or smart phone. “The work we’re doing will be one of the very few parent interventions that is digitized and importantly tested for effectiveness,” she says. Creating interventions for anxiety-related challenges Silverman and Lebowitz recently received a generous gift to develop and test other interventions that help parents reduce other child anxiety-related behavioral and emotional difficulties, such as restrictive eating and unexplained somatic symptoms. One of these projects in particular focuses on understanding the risks of social media and its potential benefits, including offering a sense of connection. “A lot of research has focused on the idea that social media is harmful and the less of it the better,” says Lebowitz. “But we actually see is that this is not quite right—there are negatives, but there are also positives. So, we’re trying to get a little bit more nuanced of a picture.” The team is working with teens with social anxiety and their parents over an extended period to better understand their social media habits and how their anxiety levels affect engagement with different platforms. The teens will answer questions sent to an app on their phones about mood and social media usage in an effort to capture emotional responses as they unfold. “We hope to develop interventions that can help make the best of social media while protecting against the more problematic effects,” Lebowitz says. The brain’s role in anxiety Researchers are also testing therapies to address anxiety at the neurological and molecular levels. In collaboration with Dylan Gee, PhD, professor of psychology in Yale's Faculty of Arts and Sciences, and Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience at Yale School of Medicine, Lebowitz and Silverman are using brain imaging to identify changes in a child’s brain before and after parents enroll in SPACE. In one study, children viewed anxiety-inducing images while undergoing magnetic resonance imaging (MRI); the researchers conducted scans with and without the children’s parents nearby. Before SPACE, children’s brains were better able to activate the regulatory circuitry needed to turn off an anxious response when their parents were nearby. But after SPACE, children could activate this circuitry even without the parent around. “As parents work on gradually reducing some of their accommodations, you can see a child get better at regulating their own fear system in the brain,” Lebowitz says. “It’s remarkable.” Research into the molecular underpinnings of anxiety can also inform new childhood anxiety treatments. In a recent study, Lebowitz, Silverman, and Flora Vaccarino, MD, Harris Professor in the Child Study Center, discovered that a protein known as fibroblast growth factor 2 (FGF2) could be protective from the toxic effects of stress. FGF2 levels in children and their parents were linked to the children’s risk of developing anxiety and depression, the study showed. The findings could help explain why some children who are exposed to early life trauma such as poverty or abuse are more prone to developing mental health disorders. And FGF2 could be a target for treatment. “This is very novel because it starts to give a clue to what is the molecular chain that connects those lived experiences to the actual psychological outcomes,” Lebowitz says. New ways to study and treat childhood anxiety Michael Crowley, PhD, associate professor in the Child Study Center, collaborates with Silverman and Lebowitz to study the role that attention plays in development and maintenance of childhood anxiety. There is a large body of research that shows that anxious children, like anxious adults, are prone to focus on threatening stimuli such as angry faces compared with neutral faces. This has led to innovative interventions that involve attention retraining. The idea is that if experts train children to look away from threatening stimuli, it may reduce their anxiety—especially children with social anxiety who are most prone to attend to threats. The researchers have just completed a clinical trial for attention retraining with 10- to 14-year-olds with social anxiety disorders and are currently analyzing the findings. Besides this innovative attention retraining research, as Crowly notes, “I like to design tasks that are engaging to kids,” Crowley says. “My goal is to assess something without the kids knowing what we are assessing.” With this goal in mind, Crowley has created a virtual game, named Boom, to study threat processing in children with anxiety disorders. The game is similar to that of hot potato—the child and three digital players take turns virtually passing a ball to each other’s gloves. At some point, the ball turns into a bomb, and as the bomb lands in each player’s glove, the outline of the glove turns yellow. The goal is to avoid having the bomb go off in your glove. What isn’t obvious is that the game is designed to measure different types of threatening stimuli, both ambiguous and direct. In the game, the direct threat occurs as the bomb is traveling towards your glove. The ambiguous threat is the yellow outlined glove as it is unknown where the bomb will travel next. While children play the game, Crowley’s team measures their brain activity using electroencephalography (EEG). The researchers have discovered that in kids with anxiety, the brain reacts more strongly to ambiguous threats than it does in their peers, but less strongly to direct threats. They believe that the initial abnormally large brain response to not knowing where the bomb is going impairs the brain's ability to properly respond when the threat is actually traveling the child’s way. “The brains of children with anxiety are unable to differentiate between threats you need to do something about and those that are not your problem.” Michael Crowley, PhD, develops innovative games for studying anxiety in children and adolescents.Credit: Matt Bradbury Based on these insights, Crowley hopes to study whether interventions like attention training could restore appropriate threat processing. Crowley’s team is also working on a test called the Balloon Risk Avoidance Task, which evaluates risk-taking and avoidance behaviors. It features a digital balloon that is full of air and about to burst. Kids have six seconds to let air out of the balloon. The more air they let out, the less risk they face that the balloon will pop. But at the same time, the balloon becomes less valuable as it deflates. “The more air you keep in the balloon, the more points you get,” Crowley explains. So far, the researchers have found that when the balloons pop unexpectedly, teens with social anxiety show distinct brain responses. Studying these responses can help psychologists understand the underlying pathways driving the various manifestations of anxiety. The genetics of anxiety When Thomas Fernandez, MD, associate professor in the Child Study Center and of psychiatry, was still in training, there was a lot of excitement about understanding the genetics associated with autism spectrum disorder. Since then, scientists have identified around 250 genes associated with autism. The genetic contribution to anxiety disorders, on the other hand, has historically received less attention. Anxiety is less heritable than autism, but the genetic contribution for anxiety disorders that emerge in childhood may be higher than for anxiety disorders overall. While scientists estimate the heritability of anxiety disorders in general to be around 30% to 50%, some studies suggest higher heritability for certain childhood-onset anxiety presentations. “I saw firsthand how researchers in the field went about finding vulnerability genes for autism,” Fernandez says. “So, we’re using a very similar playbook for childhood anxiety.” “I saw firsthand how researchers in the field went about finding vulnerability genes for autism. So, we’re using a very similar playbook for childhood anxiety.” Thomas Fernandez, MD Associate Professor In the Child Study Center and in Psychiatry Now, Fernandez and Emily Olfson, MD, PhD, assistant professor in the Child Study Center, are studying children and their parents to identify genetic changes that are present in the child but not the parents, known as “de novo mutations.” “All of us have some de novo mutations—maybe about 50 to 100 sprinkled throughout the genome,” Olfson says. “But when they occur within the coding regions of genes, they can be really disruptive.” Previous research shows that people with autism have higher rates of damaging de novo mutations than the general population. In 2022, Olfson, Lebowitz, Silverman, and Fernandez published a study on 68 children and their families that found that children with anxiety had similarly high levels of these mutations. Studying de novo mutations can help point the researchers to where they should be looking for genes associated with anxiety. “The end game is using the genes to steer us toward the right part of biology that we can then target to come up with better treatments,” Fernandez says. Building on those findings, the team is now studying more families to better understand how these de novo mutations, along with other genetic and environmental factors, shape pediatric anxiety disorders. They recently received a National Institutes of Health grant to enroll 750 new families over the next five years. Olfson is the principal investigator, with co-investigators Lebowitz, Fernandez, Silverman, and Shuangge Steven Ma, PhD, department chair and professor of biostatistics at Yale School of Public Health. Neurodevelopment, Risk Genes, and Mental Health Conditions - The Olfson Lab Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, is interested in how different anxiety disorders differ genomically. “We are studying social phobia, panic disorder, and generalized anxiety disorder, working to understand why people differ in their risk to these specific anxiety disorders and evaluating various risk factors,” he says. Gelernter was recently involved in one of the largest studies to date of the genomics underlying anxiety disorder. The study included around 122,000 people with anxiety disorders and around 730,000 without. It found that some genetic differences associated with anxiety were linked to signaling that helps reduce overactivity in the nervous system. Many anxiety medications available today work by targeting this process. “It’s nice when the biology that you get out of a large genome-wide study ratifies things that we already know because that can help increase confidence in further findings from the study,” Gelernter says. Uncovering the neurobiology of psychiatric disorders John Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and chair of the Department of Psychiatry, is interested in the neurobiology of psychiatric disorders, including post-traumatic stress disorder (PTSD), of which anxiety is a major symptom. In the late 1980s, Krystal’s team discovered that the drug yohimbine activated symptoms in patients with PTSD. “This was the first time we could link a specific biological mechanism to the symptoms of PTSD,” Krystal says. At the time, he adds, this finding was highly controversial. “A lot of people felt that PTSD was a purely psychological syndrome that didn’t have an underlying biology.” Since then, Krystal has dived deep into understanding the neurobiology of PTSD to learn how to better treat it. His team is evaluating the use of ketamine and psychedelics. These would be among the first treatments to be developed specifically for PTSD. They may also be applicable for other disorders including anxiety disorders, Krystal adds. An important gap in PTSD treatment is the absence of biological tests that inform how to best help patients manage their PTSD symptoms. A doctor doesn’t diagnose cancer based on how they feel. Rather, they use tests of the biology of the cancer to determine the best course of treatment. “And we can’t do that in any psychiatric disorder other than Alzheimer’s disease,” Krystal says. “But now we are building a foundation for this approach to the treatment of anxiety disorders for the first time.” Source: Yale School of Medicine
Northwest Arkansas growing pains, national concerns top issues at Springdale political gathering
Rain and overcast skies didn’t dampen the mood at the annual Chickin, Peelin’ & Politickin’ event Thursday at Springdale’s Shiloh Square as residents, business owners and elected officials networked over plates of fried chicken and shrimp.
'To Catch a Predator' pioneered public shaming as entertainment. Now everyone's doing it.
The 2000s sting show is finding millions of new viewers online, and its brand of public humiliation looks awfully modern.
Search for life on Mars takes major leap forward. Scientists detect longest organic molecules on planet to date | BBC Sky at Night Magazine
Scientists make discovery analysing rock pulverised for study by Curiosity rover. Largest organic compounds found on the Red Planet to date.
The Nobel Prize Week Is Kicking off in Stockholm With the Medicine Award
STOCKHOLM (AP) — This year's Nobel Prizes will kick off on Monday with the awarding of the medicine prize at the Karolinska Institute in Stockholm. Last year, three scientists won the Nobel Prize in medicine for discoveries about how the immune system knows to attack germs and not our own bodies.
Trump heads to Nebraska on Monday, where his plan to import more beef has angered ranchers
President Donald Trump is campaigning in Nebraska on Monday alongside GOP Sen. Pete Ricketts.
NYC health officials investigating Queens building after 2 confirmed cases of Legionnaires
Sacramento sisters honor family legacy with dried fruit business
Three sisters in Sacramento have launched Stained Glass Fruit, a company that turns California-grown citrus into dried slices, blending their family’s agricultural history with entrepreneurship.
2 confirmed cases of Legionnaires' disease at Queens apartment complex prompt NYC Health Department probe
The city Department of Health is investigating an apartment building in Queens, following two confirmed cases of Legionnaires' disease among the residents there.
Rogers Center to host Science and Outdoor Career Exploration Night for area students
SHERBURNE — For many curious youngsters, an ideal career is one that can take them outdoors. From 5 to 7 p.m. on Thursday, Oct. 8, the Rogers Environmental Education Center
FBI Director Kash Patel gets engaged to longtime girlfriend, country singer Alexis Wilkins
FBI Director Kash Patel and longtime girlfriend Alexis Wilkins are announcing their engagement on social media.
Jeffries says House Democrats reaching to flip Trump districts in attempt to repeat their 2018 sweep
House Democratic leader Hakeem Jeffries says his party is on track to win back control of the House.
Buccaneers vs. Cowboys odds: Opening lines for Week 5 matchup
The Tampa Bay Buccaneers hit the road on a short week as they travel to Dallas to take on the Cowboys Thursday night. Tampa Bay remains winless on the season while Dallas is coming off a big road victory. So what are the oddsmakers thinking of the Week 5 matchup between the Bucs and Cowboys? […]
Worst-Case Scenario for Bucs’ Mayfield Revealed
A dislocated thumb sidelines Baker Mayfield for up to six weeks, forcing undrafted rookie Jalon Daniels to lead a winless roster and salvage Tampa Bay’s fading season.
Concord mental health awareness walk draws around 2,000 people, organizers say
The state's largest mental health awareness and suicide prevention event drew roughly 2,000 people to Concord, according to organizers.
Cowboys vs. Buccaneers odds: Opening lines for Week 5 matchup
The Cowboys are BIG favorites for Thursday night.
Fareed Zakaria on his takeaways from top tech meeting and what’s difficult about regulating AI
President awards state scholarships to distinguished figures in education and science
President Volodymyr Zelensky has awarded state scholarships to 16 distinguished figures in education. — Ukrinform.
iPhone Duo shows what the future of smartphones could look like
Since the unveiling of iPhone Duo, the idea of all major interface navigation elements being accessible from your thumb has...
Health department hears concerns over access to medical psilocybin
Advocates warn rules could restrict access to veterans, rural residents and end-of-life care patients who seek medical psilocybin for a range of health problems.
Is a politics of 'competition within consensus' possible?
Türkiye’s new parliamentary year will test whether political competition can coexist with consensus on national priorities
Ceiling collapse causes neighboring business to close in Northern Colorado
A roof collapsed at a business under construction in Loveland this week, forcing another nearby business to close as well.
Advocate Health Care breast cancer patients honored during Bears-Jets game at Soldier Field
The ten patients, along with their family members and care teams, were honored and celebrated Sunday's annual Real Bears Fans Wear Pink game.
Ethan Hawke names surprising thriller co-starring ex Uma Thurman as his breakout: ‘Changed my life’
If you ask Ethan Hawke, it wasn’t ‘Dead Poets Society’ or ‘Reality Bites’ that gave him his big break — it was this under-seen, experimental thriller from a master of indie cinema that made him a star.
Josh Allen Sets Bills Record Against the Patriots
The dual-threat quarterback surpassed Hall of Fame legends Andre Reed and Thurman Thomas, etching his name atop the franchise leaderboard with a historic first-half touchdown plunge.
Roof collapses at Northern Colorado business
Booked, busy and really pregnant: 'Verity' star Anne Hathaway's nonstop year of blockbusters
Hathaway's Instagram bio — a casual list of the five films she's starred in this year — is further proof of how busy she's been.
AI, data science leaders join Cornell’s Radical Collaboration initiative
Cornell is expanding its expertise in artificial intelligence and data science thanks to the arrival of new faculty, with support from the Radical Collaboration initiative, building a research community that reaches across disciplines.
On cusp of merger, 'Digger bombs for Warner Bros., 'Verity' takes No. 1 at box office
On the cusp of the studio’s merger with Paramount, Warner Bros.
All INdiana Politics: Albright and Forrestal battle for closely divided seat in Senate District 31
INDIANAPOLIS — One of Indiana’s most competitive Senate districts is the site of a high-stakes showdown as a family physician and a former sheriff vie for the seat vacated by Republican Sen. Kyle Walker. Senate District 31 covers Delaware and Fall Creek townships in Hamilton County, including most of Fishers, along with Lawrence and parts […]
Seacoast Science Center experts to speak
NEWBURYPORT — Storm Surge, Newburyport’s all-volunteer climate education nonprofit, kicks off its fall 2026 Speaker Series on Thursday, Oct. 8, at 7 p.m. with “Climate Impacts on Marine Mammals: Stories
AI’s Real Gift to Science
Advanced models can help researchers sort through mountains of biological data.
California agencies use confidentiality agreements to keep some Bay-Delta science secret
California state agencies have quietly been using confidentiality agreements to keep some scientific data and discussions behind the Newsom administration's updated Bay-Delta plan a secret, raising concerns about transparency in the rule-making process.
California voters to decide Prop 45 to change how environmental laws impact key construction
California voters this November will decide Proposition 45, a measure that could change the state’s environmental laws to speed up construction projects such as housing, bridges, and clean energy infrastructure.
Don Wagner explains why he should be California's next Secretary of State
Orange County Supervisor Don Wagner, a candidate for California secretary of state, outlined his qualifications, election reform priorities, and vision for the office during an interview on California Politics 360.
Congressman Sam Liccardo urges U.S.-China cooperation on AI safety
Representative Sam Liccardo is advocating for Congress to take action on artificial intelligence safety, emphasizing the need for international collaboration with China to address critical risks and establish verification mechanisms.
California Politics 360 full episode
In Washington, D.C., President Donald Trump gathered leaders of major tech companies this week to talk about AI rules moving forward.
Hassett blames ‘partisan pollsters’ for pessimistic consumer sentiment and says ‘the economy is booming’
Rare 1-in-100M ‘Ghost Lobster’ Will Be Put to Work Helping Scientists Crack Genetic Mystery
A ‘ghost’ lobster so rare that the odds of finding it are 1 in 100 million is going to school—a new home at Maine’s Marine Science Center.
How do e-ink displays work? The science behind digital paper
How do e-ink displays work? Here’s how charged pigment particles, electric fields and bistability turn electronic screens into digital paper.
Christa Pike’s attorney calls on Tennessee Gov. to commute her sentence: She’s been through ‘some really really bad’ torture
Christa Pike’s attorney calls on governor to commute her sentence: She’s been through ‘some really really bad’ torture
Samuel Alito says that political attacks aimed at Supreme Court can be "quite damaging"
Florida Department of Health backs off vaccine exemption expansion
The Florida Department of Health is moving forward with its push to remove the requirement for four vaccines for children entering schools, but has dropped its attempt to expand exemptions for the immunization requirements.
NH's Business: Homeownership affordability across the state
Fred Kocher sits down with Heather McCann with NH Housing to talk about housing availability and affordability across the state.
Could Democrats lose a Senate race in New Hampshire? A GOP candidate with a famous name tries to flip the seat
Learning the language of trees with the Orlando Science Center
The science of it: We're heading to the rainforest to dive deep into the communication of trees.
New SCSKiller Tool Targets PC Shader Compilation Stutter; Our FINAL FANTASY VII REBIRTH Test Shows Impressive Results
SCSKiller reduces shader compilation stutters in games like FINAL FANTASY VII Rebirth, improving performance from 19 stalls to 0. Available on GitHub.
Despair over future fuels political anxiety for college students on the cusp of adulthood
Many college students today are feeling anxious about their future.