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Every Mother Counts Board Visits With UAMS Institute for Community Health Innovation, Ignite
Members of the Every Mother Counts Board of Directors recently visited the University of Arkansas for Medical Sciences (UAMS) Institute for Community Health Innovation and Ignite Professional Studies and saw first-hand how community leaders are paving the way to improve maternal health outcomes in Arkansas. Founded by Christy Turlington Burns,…
Home health worker accused of taking thousands in forged checks in Lincoln County
The employee allegedly took checks from a checkbook while providing care at a patient’s house.
Romanian lawmakers back government led by independent Luca Niculescu as country seeks to end monthslong political crisis
Romanian lawmakers back government led by independent Luca Niculescu as country seeks to end monthslong political crisis.
MCG and Itiliti Health Form Partnership to Support Health Plans with CMS-0057-F Compliance
/PRNewswire/ -- MCG Health, part of the Hearst Health network and the industry's source of truth for trusted clinical guidance, today announced a strategic...
Expanding Iowa State students' poultry knowledge
Dawn Koltes wants to increase Iowa State students’ awareness of the many opportunities available within the poultry industry in Iowa and beyond.
Perot Museum Of Nature And Science Unveils $185 Million Expansion
The expanded campus is scheduled to open in late 2028
Perceptions of science and scientists shape partisan views on common vaccines
How Americans view science and scientists is strongly associated with whether they think vaccines are safe and effective - and helps explain partisan differences in perceptions of some vaccines, according to a new study led by a team from the Annenberg Public Policy Center (APPC) of the University of Pennsylvania.
Echo Electric opens Sioux Falls facility
Echo Electric, a Sonepar company and full-line electrical distributor, has opened a location in Sioux Falls.
29,000 Granite Staters Could Lose Their Health Coverage, New Study Says
A new study by the NH Fiscal Policy Institute indicates from 23,000 to 29,000 New Hampshire residents will lose their Medicaid health insurance coverage by 2028 under new federal and state regulations and requirements set to begin Jan. 1.
T-shirts and silver balls: Politics get mixed in with the profane at a Trump store
By Elle Reeve, Samantha Guff, Frank Fenimore, CNN Boones Mill, Virginia (CNN) — Walk into Trump Town USA in Boones Mill, Virginia, and you may marvel at the breadth of human creativity, as long as you’re not distracted by how the merchandise tackles some of the most controversial political issues in the most vulgar way
Medical Center Chief Communications Officer John Howser to retire
Howser, the Medical Center’s communications leader since 2012, will retire in March 2027 after nearly 40 years at Vanderbilt.
Griffin Gaming Partners and Entertainment 360 launch new company to support video game adaptations for film and TV
HITpoint Entertainment will "combine Griffin's relationships with devs and publishers with Entertainment 360's producing track record on IP-driven franchises"
Two longtime rivals seek new audiences in Oregon governor’s race. Who will persuade voters?
Despite the effective rematch from 2022, this year’s campaign trail has pushed both candidates to reach voters in opposing ideological lanes.
US Rep. Bynum seeks re-election with Democrats poised for favorable midterm
Candidates are vying for the 5th Congressional District, which the Cook Political Report, a nonpartisan elections forecaster, labels as solidly Democratic.
Christin Applegate reveals doctors misdiagnosed her with multiple sclerosis 5 years ago
Christina Applegate revealed she was misdiagnosed with multiple sclerosis, breaking down in tears as she explained that “something else is going on” after doctors said she actually didn’t have MS.
People who've finished Call of Duty: Modern Warfare 4 on the new YOLO, single-life difficulty share experiences and tips for doing so
In COD: Modern Warfare 4's new YOLO difficulty, any game over screen takes you back to the very beginning of the game. But there are some tips for beating it.
'Office Space' star Richard Riehle dies at 78
Actor Richard Riehle arrives at the premiere of New Line Cinema's 'A Very Harold & Kumar 3D Christmas' at Grauman's Chinese Theatre on November 2, 2011 in Hollywood, California. (Jason Merritt/Getty Images)Richard Riehle, known for his role in the 1999 film Office Space, has died. He was 78.A statement shared by Artists & Representatives and Wright Entertainment, Inc. announced Riehle's passing on Monday, writing, "Our industry has lost an exceptional talent, and our community has lost a truly wonderful man.""We are deeply saddened to confirm the passing of our beloved client, Richard Riehle, this past weekend," the statement said. "A remarkable actor whose career in theater, film, and television spanned nearly five decades and more than 400 projects, Richard leaves behind an extraordinary legacy."The statement continued, "Beyond his immense talent, he will be remembered for his genuine goodness, boundless kindness, and unwavering generosity, particularly toward emerging actors and filmmakers, whom he encouraged and supported at every opportunity."Born on May 12, 1948, Riehle starred in many television series and films over the years.Notable projects include Casino, The Man from Earth and Deuce Bigalow: Male Gigolo.He got his start as an actor at the University of Notre Dame, where he was involved in the University Theatre and starred in several stage productions. He went on to earn a Master of Fine Arts in acting and directing from the University of Minnesota.While he's played characters that have an "average Joe" presence, he always made the most of his brief screen time.Some roles that he is remembered for include The Quartermaster in Glory, the train guard in The Fugitive, Reverend Scroggins in Fried Green Tomatoes and Bill Cozbi in Bridesmaids.On television, he starred as Principal Ed Rooney in the 1990 series Ferris Bueller and as grandfather Walt Finnerty in the early 2000s sitcom, Grounded For Life.In 2023, he also played Warden Reynolds in Barry.Riehle is survived by his wife, Jane Latham, and their four children.Copyright © 2026, ABC Audio. All rights reserved.
Romania Politics Government
Romanian Prime Minister designate Luca Niculescu attends a joint parliament session called to give a vote of confidence for the new government team, in Bucharest, Romania, Tuesday, Oct. 20, 2026.
Experian Health Acquires eInsights, Expanding Insurance Discovery to Help Healthcare Organizations Recover Missed Reimbursements
COSTA MESA, Calif., October 20, 2026--Experian today announced its acquisition of eInsights, a healthcare technology company.
Romania Politics Government
Romanian Prime Minister designate Luca Niculescu, left, talks to the Interior Minister designate, Marian Neacsu during a joint parliament session called to give a vote of confidence for the new
Life Science Connect Acquires BrevisRefero to Expand Biopharma Outsourcing Technology Capabilities
Life Science Connect (LSC) has acquired Toronto-based BrevisRefero Corporation, a biopharmaceutical consulting firm and developer of the RFP>Navigator® platform, expanding... Read More
Man shot in front of southwest Houston bar after dispute over business ownership
A man is in critical condition after being shot in southwest Houston outside Costa Lounge VIP bar during a dispute, police report.
Could AI Use a Simple Photo of Your Face to Reveal Clues About Your Health?
A new AI model can estimate biological age and predict cancer survival outcomes using a simple photo of a patient’s face, though more research is needed before doctors will be able to use it to help them decide on treatments.
PlayStation Founder Understands Why Players Want to Keep Physical Media Alive
'I really understand that mentality'
How governments worldwide are shaping what AI can say about politics
Some governments use legitimate AI concerns as a pretext to control political discussion, particularly chatbot responses about those in power.
Cristante called up for Roma-Slovan clash
A draw against Fenerbahce and a defeat against Real Madrid. Roma’s Champions League tally needs to be increased as soon as possible. To do so, a victory will be crucial in tonight’s match at the O...
Maxwell Economist John Cawley Elected to Prestigious National Academy of Medicine
Membership in the National Academy of Medicine is one of the highest and most esteemed honors in the fields of health, medicine and medical science.
Too Lost’s latest expansion is a deal with Xelon Entertainment
Distributor and tech firm Too Lost's ambitions in the APAC region continue. It acquired Australian distributor and artist-services company Gyro·Group in July, and now it has announced a partnership with another distributor, Xelon Entertainment.
12 rising actors you didn’t know have famous parents
Having famous parents doesn’t necessarily get you the role — but it does get you in the room. Read about 12 nepo babies on the rise, including who their parents are and where you recognize them from.
Digital Science and Sunmedia Partner to Bring Research Impact Reporting to Japan's Medical Affairs Teams
Digital Science today announced a partnership with Sunmedia to help medical affairs teams across Japan understand the impact of their research.
KFF Tracking Poll on Health Information and Trust: Fall 2026 Update on Vaccine Views
The latest KFF Tracking Poll on Health Information and Trust finds about half of parents mistakenly believe spacing out vaccines is healthier for children, while confidence in many long-standing childhood vaccines is high across partisans. These findings take on new relevance following President Trump's recent executive order calling for changes in U.S. childhood vaccine recommendations, including splitting the measles, mumps, and rubella (MMR) vaccine—currently given as a single combined shot—into three separate vaccines across multiple visits.
No-party voters to decide high-stakes midterms, political expert says
A political expert says no-party voters play a major role in who wins the midterm elections.
Business Beat : Insight Coldwater Performs First Stress Echocardiogram, expanding heart care close to home
COLDWATER, MI (WTVB) - Insight Hospital & Medical Center Coldwater has successfully performed its first ec...
Hanan Al Kuwari: Executive, Minister, Diplomat - And A Middle-Power Mediator?
The State of Qatar has nominated former minister of public health Dr Hanan Mohamed Al Kuwari for Director-General of the World Health Organization (WHO). Entering a competitive contest alongside six other candidates as the WHO faces financial instability, workforce restructuring, and geopolitical fragmentation, her campaign positions her as a pragmatic, delivery-focused nominee.
‘These risks are real’: the threat of AI bioweapons
In his annual speech on threats to the nation, Sir Ken McCallum, the head of the UK’s intelligence service, MI5, warned that AI had the potential to ‘change the stakes’ on existing and even new bioweapons. To find out why, and how, Ian Sample speaks to Dr Tom Inglesby, director of the Johns Hopkins Center for Health Security and the Bloomberg School of Public Health. He explains what has governments so worried and what measures could be put in place to reduce the risks
Local men’s health activist running 60 miles to benefit non-profit Movember
The 60 miles represents the 60 men around the world the die by suicide each hour.
Bulls' Caleb Wilson Embracing Patience, Despite Glimpses of Stardom
Chicago's No. 4 overall pick is looking forward to his NBA regular season debut on Wednesday night.
Biotech firm Colossal set to return extinct bird’s egg to New Zealand
The biotech firm trying to bring extinct species back to life, Colossal Biosciences Inc., will return an egg from the flightless moa to its native New Zealand.
CAS collaborates with Microsoft to enable faster innovation in pharmaceutical, life sciences, and chemical industries
/PRNewswire/ -- CAS, a division of the American Chemical Society, today announced the availability of CAS Connections in Microsoft Copilot. The connector gives...
Scientists finally uncover why statins can cause muscle pain
Scientists have uncovered a surprising reason why statins, the widely prescribed cholesterol-lowering drugs that help prevent heart attacks and strokes, can sometimes cause muscle pain, weakness, and even severe muscle damage. Using advanced imaging technology, researchers discovered that statins can attach to a crucial protein in muscle cells and force open a channel that normally controls calcium flow. This causes calcium to leak continuously, potentially damaging muscle tissue.
CA immigration business seized over allegations of practicing law without a license
The State Bar of California raided the North American Immigration Center in Chino, calling it an unauthorized law firm
Trump’s attacks on California elections endanger democracy, repeating a pattern
Republicans questioned elections before reforms made redistricting nonpartisan. Now they accuse California of letting noncitizens vote.
How much longer will Sacramento’s progressive politics let Califia suffer?
“Cali is dying on the streets because there is no way...to help her.”
Is this America's most normal congressional race? San Diego candidates run on classic platforms
Democrat Marni von Wilpert and Republican Jim Desmond are vying for the 48th Congressional District’s swing voters with moderate, establishment politics
This institute could get $4 billion from a ballot measure. With just three workers, is it ready?
If California voters approve it, Prop. 38 will direct $4 billion to one research institute. Only one institute currently qualifies for the money.
Sponsored Content: HMG Health Matters: A Surgeon's Perspective on Breast Cancer
Dr. Cheryl Stanski, General Surgeon and Vice President of Holston Medical Group tells us what she wants every woman to know about breast cancer. She talks about the success rate, the hope, and the options now available for women. For more information and to read more please visit the Health Matters blog at HolstonMedicalGroup.com.
Romania Politics Government
Romanian Prime Minister designate Luca Niculescu arrives for a joint parliament session called to give a vote of confidence for the new government team, in Bucharest, Romania, Tuesday, Oct. 20,
Post-Shanghai ATP Power Rankings: Alexander Zverev Takes Charge
As you already know, this is not the ATP rankings list; rather, these are ATP power rankings that combine 2026 results, recent form, performance against elite opposition, current fitness, and the level each player is realistically capable of producing during the final stretch of the season. The picture has changed considerably since our pre-Wimbledon rankings. …
The Broad to move works to Paris and Leimert Park during construction
The Broad will display more than 160 works in a major exhibition at the Fondation Louis Vuitton in Paris during its final phase of construction. It will also partner with Art + Practice in Leimert Park.
“Young Sheldon” director recalls his ‘worst run-in’ with Iain Armitage in new book
The young star was apparently “pissed,” per Alex Reid.
Ten Hag opens up on Ronaldo fallout at Man Utd
Erik Ten Hag has opened up about his fractured relationship with Cristiano Ronaldo during his time at Manchester United, claiming the Portuguese forward was not prepared to meet the physical demands o...
GTA 6 is so detailed no single Rockstar employee has seen it all - which is exactly how we got shrinking horse testicles in Red Dead Redemption 2
The infamous Red Dead Redemption 2 horse testicles were an unplanned feature because Rockstar staff apparently work autonomously, which bodes well for GTA 6.
‘Like riding a roller coaster’: UNL political science professor breaks down the stress of politics
Nebraska has seen a particularly turbulent midterm election – from the controversial and litigious rise of two new political parties, to a petition fraud investigation that’s led to several arrests.
‘Like riding a roller coaster’: UNL political science professor breaks down the stress of politics
Nebraska has seen a particularly turbulent midterm election – from the controversial and litigious rise of two new political parties, to a petition fraud investigation that’s led to several arrests.
iPhone Duo orders limited to two per customer as Apple tackles scalping
Apple is limiting iPhone Duo orders to a maximum of two per customer in the US, UK, and elsewhere after...
How Much Of Cisco Stock's Rise Did The Business Earn?
Cisco Systems (CSCO) supplies businesses and the hyperscalers building AI infrastructure with networking and security products, along with services. The company's stock climbed 92% between late July 2021 and mid-October 2026, before dividends. A rally of that magnitude makes it natural to credit a growing business. So take a guess: how much of that rise came from Cisco selling more.
Nashville CARES sues TN Health over HIV care restrictions
A Middle Tennessee HIV care center is suing the Tennessee Department of Health over new rules that require proof of citizenship to access services.
SBA urges Iowans to nominate their favorite small business for an award
There are all kinds of small businesses in Iowa that we can’t do without, from diners and donut shops to tailors and auto mechanics, and it’s time to recognize those merchants that make our lives better. Ryan Lincoln, the Iowa district director of the U.S. Small Business Administration, says the agency is taking nominations for […]
JFK’s mistresses recall their ‘irresistible’ and ‘solicitous’ affairs with the president in new book
Laurence Leamer’s latest book, “Ladies Man: The Careless Heart of John F. Kennedy,” is available for purchase wherever books are sold.
'We used to go to the climate conferences together. We are not anymore': ESA official Simonetta Cheli tells us how the political landscape for Earth observation is changing
Live Science sat down with the European Space Agency's Simonetta Cheli to discuss the importance of Earth observation, how NASA budget cuts have changed the picture, and how the proliferation of private satellites could hinder our ability to view the planet.
United CEO Scott Kirby calls for wealth tax and a near-100% inheritance tax
United Airlines CEO Scott Kirby says wealth inequality threatens society and calls for a national wealth tax and steep inheritance taxes.
San Marcos relaunches support program for local businesses
The city of San Marcos re-launched its SMTX BOOST program to provide local small businesses with free training, coaching and resources.
A note to readers: Science, accountability and elections
Dear readers, As early voting begins, I wanted to share some news — and why it connects to the decisions we make at the ballot box. I’ve been selected for the inaugural cohort of the South Atlantic Climate Journalism Hub mentorship program, hosted by Covering Climate Now. I’m excited to join this group, learn from scientists and fellow journalists, and expand my science reporting. Science directly ties to governance. Local officials make decisions about where development goes, how infrastructure is maintained, what emergency preparations receive funding, and how communities rebuild after disasters. Understanding the evidence behind those decisions helps us evaluate whether our government is serving us well. Here in western North Carolina, those connections are all around us, in Lake Lure and beyond. Flood maps inform decisions about property and development. Engineering assessments help identify risks at dams and bridges. Rainfall forecasts guide emergency preparations. Geological information helps explain landslide hazards. Water testing gives communities information they need to assess conditions. Meteorologists’ knowledge and public perception of weather events shape public safety. Each involves scientific or technical knowledge. Each also raises questions about public responsibility: What did officials know? How did they use that information? What did they tell the public? What did taxpayers receive for their money? A study can identify a problem. Elected officials still have to decide what to do about it, how to pay for it, and how to explain their choices. Reporting should examine both the evidence and the response. That is where I want to strengthen my work. My reporting on Helene recovery, infrastructure, flooding, public safety, and public spending has repeatedly brought me to questions that require scientific expertise alongside public records. This mentorship may help me better understand the research, ask more precise questions, and explain the answers clearly. I also bring the perspective of someone living with these concerns. I live downstream of Lake Lure Dam, and landslides affected my property during Helene. Those experiences bring urgency to my questions. Careful reporting helps establish the answers. Readers deserve to know what the evidence shows, where uncertainty remains, and whether officials accurately describe the information guiding their decisions. You also deserve scrutiny of proposed solutions: what they cost, what they are expected to accomplish, and what risks remain. Access to that information matters. As a mostly deaf journalist who relies on written communication, I will continue pressing for written public warnings, records, and explanations that people can read and use in real time. As you consider the candidates seeking your vote, consider how they approach evidence, preparedness, and transparency. Do they support local journalism, even when it’s not parroting a press release? Do they explain weather events clearly in plain English and explain their decisions after them? Make supporting records available? Acknowledge uncertainty? Follow through when a report identifies a risk? Those are practical questions about governing. Thank you for supporting Cops & Congress and the work that makes these questions part of the public conversation. I’m grateful to David Dickson and the CC Now team for this opportunity, and I look forward to bringing what I learn back to you. Annie DanceEditor & Publisher, Cops & Congress — Learn more about this newsletter, ethics policy, how you can help shape this work, and support it. Follow on X and Facebook. Send constructive criticism, fan mail, and tips with public documents for future stories: CopsandCongress@gmail.com ICYMI: View the Cops & Congress archive — Annie Dance is the publisher of Cops & Congress, a newsletter that analyzes what happens when crime, courts, disaster, democracy, and small-town policies collide. Views expressed here are covered by the First Amendment. Dance has a Bachelor of Arts from Manhattan University in Communication with a focus in Journalism and Government. She has been a journalist for over 20 years. Share Upgrade now or give a gift subscription
Bungie plans to share first details about surprise 'unvaulting' of Destiny 2 content soon
We should learn more about Bungie's 'unvaulting' of previously removed Destiny 2 content very soon.
China’s Ultimate Political Survivor Just Fell. What That Says About Xi’s Rule.
Plus, export-driven growth rebounds, masking deepening economic problems that are creating a lost generation.
I’ve used the Pixel 11 Pro XL and iPhone 18 Pro Max, and Apple’s ecosystem isn’t enough anymore
I've used iPhones for almost two decades, and much of what made Apple's devices an easy choice has eroded.
Uzbekistan's $12bn business drive gathers pace during Rubio visit
The package covers railways, critical minerals, finance and technology, with major US firms involved. Uzbek President Mirziyoyev outlined measures to attract investors, while business executives told Euronews that commercial activity is growing.
UW Health’s East Madison Hospital expands amid patient demand
The $140 million project expands inpatient and surgical capacity as officials say increases in patient demand continue to grow.
Names in the News: People shaping the future of Lake Area business
Sowela appoints vice chancellors Sowela Technical Community College is pleased to announce the promotion of two distinguished members of its leadership team, Allison Dering and Dr. David LaFargue, from executive […]
Sensor Tower data shows the yawning gap between GTA 6 and everything else
In terms of preorder numbers, Rockstar's game is 148% head of 2022's Call of Duty: Modern Warfare 2 at this point from launch
‘A huge need’: Free healthcare day event draws hundreds to Charleston clinic
More than 400 people got medical, dental or vision care at a one-day free health care event in Charleston, West Virginia on Saturday.
LACMA, Perrotin, the new Metro and now the Brick: Todd Gray is having a banner year
Todd Gray has a solo show opening at the Brick on Oct. 18 — the cap on a banner year including a LACMA commission, a solo show at Perrotin and a public art piece for the Wilshire/La Cienega station for the D line.
Griffin William Sherry to bring folk, country, rock to The Grand
Join Maine-born singer-songwriter Griffin William Sherry and friends for an evening of powerful songwriting and live music at The Grand on Nov. 6 at 7 p.m. Experience Sherry's unique blend of folk, country, and rock and roll, rooted in his rural Maine upbringing. Get your tickets now for this unforgettable musical event.
As Hollywood implodes, is success still possible for a striving actor?
Last year 34-year-old actor Katie Folger moved from Austin into a Silver Lake casita to pursue her acting dream. Now she's performing a one-woman show called "Getting in Bed With the Pizza Man" at Elysian Theater. But will the TV pilot sell?
Envelope Insiders Live: See stars of 'Furious,' 'Love Story' and more
The creatives behind 'Furious,' 'Love Story,' 'The Only Living Pickpocket in New York' and 'Tenzing' joined us for a day of food, wine and great conversations. Take a look inside.
As Science and Technology Advance, Nurses Become More Essential to Successful Organ Transplants
Symposium of articles examines how innovations in organ donation and transplantation reinforce the vital role for critical care nurses and advanced practice nurses throughout the continuum of care for donors, candidates awaiting transplantation, recipients and their respective families.
The Data Dive: Steve Kornacki on how Susan Collins could transcend Trump in Maine
Seeking re-election in a blue state, the longtime Republican senator is relying on her personal brand to defy political gravity — again.
List of DVD release dates for Oct. 20 and beyond
Following is a partial schedule of coming movies on DVD. Release dates are subject to change: OCTOBER 20: Masters of the Universe 20: Hadestown: The Musical 20: One Night Only
Why Calling Anti-Trans Hate a “Distraction” Is So Troubling
It’s a familiar line in the midterms: Anti-trans attacks are a “distraction” from “kitchen-table” issues. That sends a chilling message about whose rights are worth fighting for.
What Is Culinary Medicine? Bridging Nutrition, Cooking, and Health
Culinary medicine combines nutrition science with practical cooking education to help patients apply dietary advice and train healthcare professionals in nutrition counseling. Studies report improvements in cooking confidence and dietary behaviors, but evidence for sustained clinical benefits remains limited.
'We lost the battle': Local businesses prepare as DEI crackdown hits OEV
New Florida law forces Tallahassee to replace its minority business aid program with a neutral alternative. Some business owners worry about the future.
France Protests Show Europe’s Shift Away From Centrist Politics
Europe’s centrist parties are losing ground among young people and workers, who are increasingly tempted by populist promises of radical change.
Republicans in competitive Pa. races are tying themselves to Josh Shapiro. What does that mean for the midterms?
Republicans in competitive swing district races are featuring Gov. Josh Shapiro in ads. It's "quite telling," one political science professor said.
France’s crisis sounds familiar. Is America next?
France is on fire, and it faces a political and an economic reckoning that feels dangerously familiar to Americans.
Vivek Ramaswamy gets a political education in a grueling Ohio governor’s race
Vivek is attempting a rare route in politics, going from national notoriety as a presidential candidate to running for state office, eschewing his hard-charging and provocative tone during his presidential campaign. He’s making his pivot during an election cycle where headwinds are blowing against all kinds of Republicans. It hasn’t been easy.
Data Centers Play Delicate Game to Weather Political Backlash
Demand for the data centers powering artificial intelligence is booming even as developers find themselves playing political defense.
Bigfoot to Bojangles: How a Charlotte family built a business on make-believe
Long before the store became a Charlotte fixture, it started with a phone call, a rack of costumes and a couple willing to take a chance.
The AI industry’s race for influence includes $100 million in campaign cash
Leading AI companies have set up political action committees to support both Republican and Democratic candidates in the midterm elections. The effort by…
'They’ve awakened him’: How a wealth tax fight made Brin a political force
After years of sporadic giving, the Google co-founder has unleashed spending that spans from the billionaire tax to housing and environmental policy.
"This act is intended to demonstrate solidarity with Palestine" - Umurangi Generation studio blocks new game Penguin Colony from being sold in Israel
"In the absence of more organised sanctions," Umurangi Generations studio Origame has blocked the sale of its new game Penguin Colony in Israel.
Threats of political violence soar in Australia’s ‘online echo chamber’
Independent lawmaker Helen Haines was in critical condition after being struck deliberately by a car.
GDC Festival of Gaming 2027 moves to four-day format to "create a higher quality, more focused and valuable experience"
"We're concentrating programming and opportunities during the days when the community is most active," say organisers
The New Reality of El Niño: Why “Business as Usual” Is No Longer an Option
A rapidly intensifying El Niño is increasing risks to operations, supply chains and workforces worldwide. Learn practical strategies to strengthen resilience and prepare for greater weather volatility
DC council member wants temporary shutdown of business where National Guard was shot
A D.C. Council member has called for the temporary shutdown of a business where police said a National Guard member was shot late Sunday.
Records reveal why AI political ads raise alarms in NY
The USA TODAY Network obtained records from state agencies tasked with overseeing AI uses in elections. See what it means for 2026 midterms.
Pfizer makes ‘business decision’ to end phase 2 trial of autoimmune drug as program’s future uncertain
Pfizer has called time on a phase 2 trial of its CXCR5 antibody in an autoimmune blood disorder, with the company tight-lipped on whether this marks the end of the road for the asset. The Big Pharma had been evaluating the therapy, dubbed PF-06835375, in a phase 2 study of 61 patients with primary immune thrombocytopenia (ITP) that kicked off in 2022, according to the federal trials register. However, Pfizer confirmed to Fierce on Monday that this study had been terminated “due to a business decision.” “The decision to terminate the trial was not based on any safety concerns,” a spokesperson pointed out. At time of publication, PF-06835375 remained listed on Pfizer’s website for both ITP and lupus. A phase 1 study in lupus wrapped up in 2022, according to the trials database. ITP is an autoimmune disorder characterized by a low platelet count. Novartis was at one point evaluating its B-cell-depleting antibody ianalumab—recently approved as Fabhalta to treat immunoglobulin A nephropathy—as a potential treatment ITP. But the therapy struggled to demonstrate a benefit in the clinic for this indication. When contacted by Fierce, Pfizer wouldn’t confirm whether all work on PF-06835375 has been halted, and whether the company has any other plans to explore C-X-C chemokine receptor type 5 (CXCR5) as a mechanism. CXCR5 is found in blood cancers such as diffuse large B-cell lymphoma and mantle cell lymphoma chemokine receptor. However, there is little expression in normal tissue, which has led some drug developers to explore its potential. Vincerx Pharma had at one point been planning to take an anti-CXCR5 ADC into the clinic to treat B-cell malignancies, but that ambition was scrapped due to cash constraints. Where Big Pharma is placing its bets is one of the hot topics being discussed at Fierce Biotech's high-impact event in London next month. Find out more information and register by clicking on the banner below: [ ](https://qtxasset.com/quartz/qcloud5/media/image/where_big_pharma_is_placing_its_bets.png?VersionId=B8JrRbJ.pFUSK1pJgjeWHLGm_18RdLAy)