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Results for " american " 6,223 found 🔀 AI-powered Shuffle

Master pianist Swann to perform Goldberg Variations

The Winter Harbor Music Festival will welcome internationally acclaimed pianist Jeffrey Swann for a special performance of J.S. Bach’s Goldberg Variations, BWV 988, on Saturday, July 11, at 7 p.m.

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Jun 28 • 4:00 PM EDT • Entertainment • ellsworthamerican.com
Zohran Mamdani says he and allies he endorsed carry a ‘national message’

Mayor says progressive peers who swept primaries speak to Americans ‘coast to coast’ as moderates have reservations

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Jun 28 • 2:24 PM EDT • Politics • theguardian.com
American Airlines flight aborts takeoff at MIA after business jet enters runway

An American Airlines flight to Bermuda aborted its takeoff after a business jet entered the same runway at Miami International Airport on Saturday evening.

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Jun 28 • 1:18 PM EDT • Business • local10.com
Trump’s Great American State Fair attendees say they haven’t noticed politics overshadowing the celebration

The gloomy, overcast weather on Saturday didn’t disturb visitors who attended the first weekend of President Donald Trump’s Great American State Fair, an event commemorating America’s 250th anniversar...

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Jun 28 • 12:30 PM EDT • Politics • yahoo.com
Trump’s Great American State Fair attendees say they haven’t noticed politics overshadowing the celebration

President Donald Trump kicked off the event with a headlining speech Wednesday after musical acts dropped out of the lineup citing concerns over partisanship.

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Jun 28 • 12:30 PM EDT • Politics • nbcnews.com
High-Signal Publisher
Sarasota Business Awards honor innovation, entrepreneurship and the American spirit

The Greater Sarasota Chamber of Commerce recognized businesses in the community across 10 categories.

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Jun 28 • 12:00 PM EDT • Business • yourobserver.com
'All INdiana Politics'

U.S. Sen. Todd Young has said that a proposed $300 billion payment to Iran would not be funded by American taxpayers, and that any ceasefire with Iran must be contingent on the dismantlement of its nuclear program, while Indiana Senators Young and Banks have split on a housing bill now awaiting President Trump's signature.

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Jun 28 • 10:21 AM EDT • Politics • wishtv.com
Mamdani Says Primaries Show Voters Want a New Kind of Politics

New York City Mayor Zohran Mamdani said he believes Tuesday’s state primaries, where the slate of progressive candidates won, show that American voters are looking for a “new kind of politics.”

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Jun 28 • 10:20 AM EDT • Politics • bloomberg.com
Americans find common ground on healthcare

Americans agree that healthcare needs to be better, cheaper, and less complicated. Good ideas toward those goals are bubbling up around the country.

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Jun 28 • 8:27 AM EDT • Health • npr.org
High-Signal Publisher
Jodi's Journal: The purple city prevails

No matter who emerges in this election, the purple city has prevailed. And I think that's a win.

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Jun 28 • 8:00 AM EDT • Business • siouxfalls.business
Humor laurels for comedian Bill Maher as the Kennedy Center navigates Trump-era upheaval

Comedian Bill Maher is set to receive the Mark Twain Prize for American Humor at the Kennedy Center.

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Jun 28 • 7:38 AM EDT • Entertainment • seattletimes.com
Humor laurels for comedian Bill Maher as the Kennedy Center navigates Trump-era upheaval

Comedian Bill Maher is set to receive the Mark Twain Prize for American Humor at the Kennedy Center.

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Jun 28 • 7:37 AM EDT • Entertainment • ksat.com
Humor laurels for comedian Bill Maher as the Kennedy Center navigates Trump-era upheaval

Comedian Bill Maher is set to receive the Mark Twain Prize for American Humor at the Kennedy Center.

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Jun 28 • 7:37 AM EDT • Entertainment • click2houston.com
Humor laurels for comedian Bill Maher as the Kennedy Center navigates Trump-era upheaval

Comedian Bill Maher is set to receive the Mark Twain Prize for American Humor at the Kennedy Center.

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Jun 28 • 7:37 AM EDT • Entertainment • news4jax.com
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Americans now live longer in Democratic-held House districts. Here’s why

Even as health care issues rise in the 2026 campaign debate, new data show that far more House Republicans than Democrats represent districts where the most residents face major medical challenges — and lack health insurance.

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Jun 28 • 6:30 AM EDT • Health • cnn.com
Again, Trump said nobody left his speech. Again, that wasn’t true

President Donald Trump posted on social media on Thursday about the speech he gave the day prior to kick off the Great American State Fair in Washington, DC: “Everybody stayed right until the end of my Speech because they loved hearing about a truly successful America.”

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Jun 28 • 6:30 AM EDT • Politics • cnn.com
Costs of Iran war will linger despite conflict's end, experts say

The effects of the war and other factors driving inflation are likely to stick around for months, experts say, presenting an ongoing challenge to American households.

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Jun 28 • 6:00 AM EDT • Politics • latimes.com
Kevin O'Leary's latest villain arc: data centers

Kevin O'Leary, the acerbic "Shark Tank" investor, is everywhere trying to sell a skeptical American public on the idea of a data center in their town.

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Jun 28 • 5:14 AM EDT • Business • businessinsider.com
Slate is betting Americans want less car for less money

Slate unveiled the starting price for its tiny, electric pickup truck this week. It's betting that today's overly techy cars created a white space.

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Jun 28 • 4:47 AM EDT • Business • businessinsider.com
‘Photo I.D. should be at the core.’ Rep. Byron Donalds on polling that Americans favor requiring a photo I.D. to vote
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Jun 27 • 10:03 PM EDT • Politics • cnn.com
American Airlines flight aborts takeoff in Miami after business jet enters the same runway

An American Airlines flight headed to Bermuda aborted its takeoff in Miami Saturday evening after a business jet entered the same runway, getting as close as a third of a mile apart at one point.

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Jun 27 • 9:42 PM EDT • Business • cnn.com
American Airlines flight aborts takeoff in Miami after business jet enters the same runway

An American Airlines flight headed to Bermuda aborted its takeoff in Miami Saturday evening after a business jet entered the same runway, getting as close as a third of a mile apart at one point.

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Jun 27 • 9:42 PM EDT • Business • cnn.com
14 unique ways to celebrate America’s 250th birthday

Fireworks, hotdogs and summer blockbuster movies are Independence Day staples. But this year brings a flurry of unique and alternative events where Americans can come together, put aside our differences,

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Jun 27 • 6:00 PM EDT • Entertainment • wqow.com
Senators, Pennsylvania businesses to represent Commonwealth at Great American State Fair

WASHINGTON, D.C. (WHTM) — Pennsylvania will be represented at the Great American State Fair after all. The Commonwealth’s delegation to the U.S. Senate announced a planned “strong…

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Jun 27 • 4:38 PM EDT • Business • abc27.com
3 million Americans have dropped Obamacare health coverage over past year, after Republicans let federal subsidies expire

KFF expects the total number of people in the government healthcare program to continue to decline throughout the year, potentially to a low of about 17.5 million from 19.2 million now.

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Jun 27 • 4:21 PM EDT • Health • fortune.com
Dean Cain discusses stark contrast in patriotism among political parties

Actor Dean Cain joins 'Fox News Live' from the Great American State Fair in Washington, D.C., to share his take on patriotism and a tense border hearing with DHS Secretary Mullin.

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Jun 27 • 2:16 PM EDT • Politics • foxnews.com
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The sky is not falling. Americans are getting healthier.

Despite declining obesity and heart disease rates, increasing cancer survival rates, and a record high life expectancy, politicians from both parties are pushing costly and ineffective policies to …

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Jun 27 • 2:00 PM EDT • Politics • thehill.com
HISTORY IN THE MAKING: A RECORD-BREAKING OPENING DAY AT THE PAN AMERICAN ATHLETICS CHAMPIONSHIP MEDELLÍN 2026

The Pan American Athletics Championship delivered everything the Americas had been waiting […]

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Jun 27 • 1:48 PM EDT • Sports • panamsports.org
Five Million Americans Lost ACA Health Insurance—Here’s What That Could Mean For Public Health

New data shows 5 million Americans have lost health insurance through the ACA. A doctor breaks down the downstream consequences for public health in America.

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Jun 27 • 11:26 AM EDT • Health • forbes.com
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The NHL's Obsession With No-Trade Clauses: Why Hockey Is The Outlier In North American Sports

No-trade and no-move clauses have become so commonplace in the NHL that many fans assume they are simply part of the business of sports. They aren’t.

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Jun 27 • 8:25 AM EDT • Sports • forbes.com
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4 iconic American CEOs are making way for nuts-and-bolts leaders

Warren Buffett, Tim Cook, Bob Iger, and Doug McMillon are making way for nuts-and-bolts leaders, but success will require more than an eye for detail.

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Jun 27 • 5:43 AM EDT • Business • businessinsider.com
J. William Fulbright, proponent of cultural exchange, left complex legacy across politics, education

As the Vietnam War heated up, U.S. Sen. J. William Fulbright became uncomfortable with American involvement in the conflict.

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Jun 26 • 9:00 PM EDT • Politics • arkansasonline.com
J. William Fulbright, proponent of cultural exchange, left complex legacy across politics, education

As the Vietnam War heated up, U.S. Sen. J. William Fulbright became uncomfortable with American involvement in the conflict.

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Jun 26 • 9:00 PM EDT • Politics • nwaonline.com
DNC plans weekend of local events to focus on affordability concerns under Trump

Two years ago, Democrats were the ones accused of being indifferent to Americans’ anger about rising prices. Now they're pointing the finger at Trump, who has downplayed the impact of lingering inflation.

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Jun 26 • 7:16 PM EDT • Politics • pbs.org
Screens are virtually inescapable. What are they doing to our health?

They’re in our pockets, workplaces, homes and schools — screens are everywhere. Americans are spending more than seven hours a day looking at screens. What is this doing to our well being? And does all this screen time affect different generations differently? Horizons moderator William Brangham explores what we know and don’t know with researchers Kostadin Kushlev and Courtney K. Blackwell.

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Jun 26 • 7:00 PM EDT • Health • pbs.org
Americans keep poisoning themselves with semaglutide, other weight loss drugs

These incidents became much more common after the FDA started approving GLP-1 drugs for chronic weight management in 2021.

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Jun 26 • 4:52 PM EDT • Business • cardiovascularbusiness.com
The mediocre American League will define this year's MLB trade deadline
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Jun 26 • 4:12 PM EDT • Sports • sports.yahoo.com
Honda Strengthens Power Sports & Products Business With More Unified Structure

American Honda announced a restructuring of its Power Sports & Products center, aligning its Powersports, Power Equipment and Marine divisions under a unified structure.

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Jun 26 • 2:30 PM EDT • Business • cyclenews.com
Axios Live: "Health care costs are scaring people," Rep. Dingell says

Americans are not just thinking about the high prices of health care — they're afraid of them

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Jun 26 • 1:45 PM EDT • Health • axios.com
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Your Social Security benefits could be cut by a quarter in 2032. Here’s what to know

Americans’ Social Security benefits will have to be cut by roughly a quarter in six years due to depleted funds, according to a June 9 report from the Social Security Board of Trustees. That’s months sooner than the group had estimated in 2025.

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Jun 26 • 1:17 PM EDT • Politics • pbs.org
DAVID MARCUS: In rural Maryland, petty politics takes back seat to World Cup fever

The World Cup and America 250 celebrations unite Americans beyond politics, as the Save America Act and Trump debates fade in small-town gatherings.

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Jun 26 • 1:14 PM EDT • Politics • foxnews.com
Scientists Baffled by Discovery of Rare “Pink Floyd” Spider Hidden in Home Walls - Futura-Sciences

The Birth of a “Pink Floyd” Spider Tiny, discreet, and quietly settled on urban walls, a new species of spider was recently discovered in Colombia—and christened as a tribute to the iconic rock band Pink Floyd. As part of a study published in the journal Zoosystematics and Evolution, South American...

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Jun 26 • 1:00 PM EDT • Science • futura-sciences.com
Evoke Entertainment Signs Tribeca-Honored Filmmaker Elisee Junior St. Preux

EXCLUSIVE: Evoke Entertainment has signed Haitian American filmmaker Elisee Junior St. Preux, whose debut feature The Tropic Sun and His Eyes world premiered in Tribeca’s Viewpoints section and earned...

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Jun 26 • 1:00 PM EDT • Entertainment • nz.news.yahoo.com
Walton Arts Center to host blood drive with free entertainment July 1

The Walton Arts Center will host a blood drive in partnership with the American Red Cross from 10 a.m. until 4 p.m. on Wednesday, July 1. The center will provide live entertainment for blood donors in attendance that day, including performances by cellist Carrington Truehart, and guitarists Ben Harris and William Reyes. SUBSCRIBE: Get our

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Jun 26 • 12:28 PM EDT • Entertainment • fayettevilleflyer.com
PepsiCo Q2 earnings expected to reflect weakness in North American snack business, delayed recovery

PepsiCo Inc (NASDAQ:PEP, XETRA:PEP) earnings outlook was trimmed by Bank of America analysts ahead of the company’s second quarter results, with softer-than-expected performance in its North American snacks business offsetting steadier international trends. The analysts lowered their fiscal...

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Jun 26 • 12:25 PM EDT • Business • finance.yahoo.com
Small Business Central to American Prosperity Celebration

House Small Business Committee celebrates small businesses as key to American prosperity ahead of nation's 250th anniversary. Learn why Main Street matters.

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Jun 26 • 12:16 PM EDT • Business • legis1.com
From The Sports Desk: The U.S. lost, but also saw return of star Christian Pulisic

The Americans may have lost their final group stage. But Pulisic, who had been nursing a calf injury, returned to action. He’s back just in time for the start of the knockout round.

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Jun 26 • 11:06 AM EDT • Sports • nbcnews.com
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NASA’s PACE Mission Studies Smoke, Fires

With the North American fire season underway, and a record number of acres already burned nationwide, NASA’s Plankton, Aerosol, Cloud, and ocean Ecosystem

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Jun 26 • 10:00 AM EDT • Science • science.nasa.gov
New York’s primaries signal a new force in US politics

Progressive, Muslim and Arab American candidates are challenging old limits on debate over Israel and Palestine.

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Jun 26 • 9:37 AM EDT • Politics • aljazeera.com
Whole Hog Politics: It was voters, not Senate Republicans, who forced Trump’s hand on Iran

The early returns are in, and we can pretty safely say that Americans like the peace with Iran but strongly dislike the war that it ended. The truce is shaky, with hour-by-hour challenges that seem...

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Jun 26 • 9:27 AM EDT • Politics • aei.org
Trump wants the US military to be rent-a-cops

A mercenary vision of American power.

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Jun 26 • 6:30 AM EDT • Politics • vox.com
Williams to begin Wimbledon comeback against Joint

American superstar Serena Williams will make her highly-anticipated singles comeback at Wimbledon against Australia's Maya Joint in the first round.

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Jun 26 • 5:38 AM EDT • Sports • sports.yahoo.com
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Salpointe flag football QB named MaxPreps Freshman of the Year

It is the first year that MaxPreps is putting together an All-American team as the sport continues to gain popularity.

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Jun 25 • 9:11 PM EDT • Sports • sports.yahoo.com
Dems put on blast over poll that shows record-low patriotism in US: 'Tear our society apart'

Rep. Harriet Hageman raises alarm over Gallup poll showing just 17% of Americans were "very proud" of their country, a record low in 25 years.

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Jun 25 • 7:54 PM EDT • Politics • foxnews.com
Larry David and Barack Obama's American history show is deeply cringe

For Larry David and Barack Obama, history is a laughing matter. And they've got the sketch comedy show to prove it.

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Jun 25 • 7:37 PM EDT • Entertainment • centraloregondaily.com
Justices Clash on Whether Race Played a Role in Trump’s Bid to Deport Haitians

The split mirrored one that has long divided Americans: how seriously to take the president’s loose, provocative and sometimes ugly remarks.

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Jun 25 • 5:37 PM EDT • Politics • nytimes.com
PAHO mobilizes emergency health response following earthquakes in Venezuela

Caracas, Venezuela/Washington, D.C., 25 June 2026 (PAHO) – The Pan American Health Organization (PAHO) has activated its emergency response mechanisms to support the health response in Venezuela following two magnitude 7.5 earthquakes that struck the country on June 24.

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Jun 25 • 4:53 PM EDT • Health • paho.org
WATCH: Kellyanne Conway insists socialist primary victories don't reflect American values nationwide

Kellyanne Conway says Democratic primary wins reflect only a handful of specific districts and do not signal a broader political shift nationwide.

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Jun 25 • 4:49 PM EDT • Politics • foxnews.com
Making Our Own Luck

We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.

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Jun 25 • 4:48 PM EDT • Science • goodscience.substack.com
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How open are Americans to socialism, after all?

Democratic socialists might be having their best year ever.

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Jun 25 • 4:42 PM EDT • Politics • cnn.com
Earthquakes Have Often Shaken Latin American Politics

How governments respond to natural disasters can shape their political trajectories, an expert writes.

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Jun 25 • 4:19 PM EDT • Politics • americasquarterly.org
These Churches Are Putting Family Before Politics

Close to 70 percent of Black children in America are born to unmarried parents. Nearly half live with a single mother. Both figures are significantly higher than the national average and reflect the steep decline in marriage among African Americans since the 1960s.

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Jun 25 • 3:52 PM EDT • Politics • heritage.org
Check politics at the door? Not at many workplaces, researcher says

When people think of workplace segregation, they usually think of race or gender. Yet Americans are also sorted at work by something employers rarely measure: how they vote.

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Jun 25 • 2:40 PM EDT • Politics • phys.org
Sofia Elverdin Selected as Co-Recipient of the Best Dissertation Prize From the American Political Science Association’s Women, Gender and Politics Section

Sofia Elverdin, assistant professor of politics at Washington and Lee University, was recently selected as a co-recipient of the American Political Science Association’s (APSA) Best Dissertation Pr…

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Jun 25 • 1:25 PM EDT • Politics • columns.wlu.edu
Americans Are Not Buying White House’s Trump Health Claims

New polling shows what a majority of Americans really think of the explanations about 80-year-old Trump.

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Jun 25 • 1:25 PM EDT • Health • thedailybeast.com
From the Beginning, Politics Triggered Broadcasting

Media scholars argued that politics, not technology, shaped American broadcasting from 1927 on, repeatedly shielding incumbents from competition.

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Jun 25 • 1:05 PM EDT • Politics • broadbandbreakfast.com
MIT in the media: Exploring how curiosity-driven science is an essential ingredient in America’s success

“Scientific American” showcases the history and future of America’s scientific engine, highlighting promising young scientists and icons at MIT and beyond.

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Jun 25 • 12:00 PM EDT • Science • news.mit.edu
Another look at carrots and eyesight; how to get more fiber; why mosquitoes bite some people and not others; plus other stories with Vanderbilt Health sources

AARP reporter Stacey Colino interviewed Milam Brantley, MD, Associate Professor of Ophthalmology and Visual Sciences, in 2020 for a story about whether eating carrots can improve vision. Sacramento Bee reporter Samantha Agate has now used Brantley’s comments in an AI-curated story created by content specialists on the same topic that has been picked up by MSN and others. Prevention magazine interviewed Heidi Silver, RD, PhD, Founding Director of the Vanderbilt Diet, Body Composition, and Human Metabolism Core, for a story about the importance of fiber and how people can get more of it in their diet. William Schaffner, MD, Professor of Preventive Medicine, was quoted by several news outlets about public health issues, including: Women’s Health (tick bites and alpha-gal syndrome); The Washington Post (tetanus); and Healthline (why mosquitoes prefer to bite some people and leave others alone). A visit to Monroe Carell Jr. Children’s Hospital at Vanderbilt by some Banana Ball baseball players was covered by The Tennessean and WZTV Fox 17 News, and The Tennessean’s story was also picked up by Yahoo! Sports. Clarksville Now published a story written by the Montgomery County Economic Development Team, whointerviewed Bradley Stancombe, MD, professor of Clinical Pediatrics, Vanderbilt Neonatology, about the new energy of Vanderbilt Clarksville Hospital and how the facility is recruiting physicians. Healio Allergy/Asthma group editorial director Richard Gawel interviewed Mark Rolfsen, MD, Clinical Fellow in the Division of Allergy, Pulmonary and Critical Care Medicine, for a story about his presentation at the American Thoracic Society meeting on metal health outcomes following ICU discharge. Nashville Scene reporter Hannah Herner interviewed James Crowe, MD, Director of the Vanderbilt Center for Antibody Therapeutics, for a story about his efforts to prepare for the next pandemic by isolating antibodies that can neutralize dangerous viruses. Medscape reporter Kathleen Doheny interviewed Neesha Choma, Associate Chief of Staff of Vanderbilt University Hospital, for a story about how hospitals can reduce readmissions.

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Jun 25 • 10:56 AM EDT • Health • news.vumc.org
GLP-1 and reduced cancer risk discovery earns UT Health San Antonio fellow prestigious Helio NextGen Disruptor Award

Colton Frisco Jones, MD, a 2nd-year fellow at the Mays Cancer Center at UT Health San Antonio, the academic health center of The University of Texas at San Antonio (UT San Antonio), recently earned the prestigious Healio NextGen Disruptor Award at the American Society of Clinical Oncology (ASCO) 2026 annual meeting in Chicago.

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Jun 25 • 10:27 AM EDT • Health • news.uthscsa.edu
First-of-its-kind discovery earns UT Health San Antonio Mays Cancer Center fellow prestigious Helio NextGen Disruptor Award

Colton Frisco Jones, MD, a 2nd-year fellow at the Mays Cancer Center at UT Health San Antonio, the academic health center of The University of Texas at San Antonio (UT San Antonio), recently earned the prestigious Healio NextGen Disruptor Award at the American Society of Clinical Oncology (ASCO) 2026 annual meeting in Chicago.

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Jun 25 • 10:27 AM EDT • Health • news.uthscsa.edu
Bo McCalebb Inducted into the Allstate Sugar Bowl New Orleans Sports Hall of Fame

NEW ORLEANS — Former University of New Orleans All-American guard Bo McCalebb reiterated how much he loved his time on the Lakefront as he was inducted into the Allstate Sugar Bowl's New Orleans Sports Hall of Fame on Wednesday night.

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Jun 25 • 10:25 AM EDT • Sports • unoprivateers.com
Supreme Court protects pesticides from some health claims in key Roundup case

The Supreme Court on Thursday restricted Americans’ ability to sue pesticide makers over alleged health harms stemming from their products. In a 7-2 ruling, the court held that some claims that pes…

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Jun 25 • 10:11 AM EDT • Health • thehill.com
Keith Flaherty: Translating Science into Medicine

Keith Flaherty: Translating Science into Medicine / American Association for Cancer Research, cancer, Keith Flaherty, Massachusetts General Hospital,

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Jun 25 • 8:47 AM EDT • Science • oncodaily.com
Americans are struggling to pay for health care. Here's why.

Fewer than half of U.S. adults said they believed they could pay for health care, medical appointments and prescriptions,

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Jun 25 • 8:09 AM EDT • Health • usatoday.com
Moody Center announces exhibition exploring math, science and tech rooted in Indigenous knowledge systems

Through a framing of North, Central and South America as interconnected regions, “Radiant Geometries: Vectors of Knowledge from the Indigenous Americas” brings together contemporary Indigenous and Latin American artists whose practices illuminate knowledge as a living technology, through which the mathematical, metaphysical and artistic realms converge.

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Jun 25 • 8:00 AM EDT • Science • news.rice.edu
Around the MHS

This edition of news from around the Military Health System for the week of June 22-26, 2026, includes a vital partnership between Offutt Air Force Base and the American Red Cross, new Uniformed Services University research on stress fractures, and Naval Medical Research Unit EURAFCENT participates in a multinational readiness exercise.

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Jun 25 • 8:00 AM EDT • Health • health.mil
What we know about Trump’s Great American State Fair

The Trump administration’s 16-day-long Great American State Fair has begun, offering visitors to the National Mall in Washington, DC, the chance to visit pavilions showcasing every US state and territory.

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Jun 25 • 6:00 AM EDT • Politics • cnn.com
Des Bishop turns a turbulent past into comedy in 'Bridge and Tunnel'

Queens-born comic Des Bishop’s new “Bridge & Tunnel” special captures his long, winding journey from Irish stardom back to New York, where he finally finds his fast-paced American voice.

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Jun 25 • 6:00 AM EDT • Entertainment • latimes.com
American fertility rates decline among women in their 30s. How does Louisiana compare?

Fertility rates in the U.S. are shifting. See the national data.

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Jun 25 • 5:00 AM EDT • Health • nola.com
You Might Find Soccer Boring but American Sports Media Are All In

Coverage of soccer has exploded with this year’s World Cup.

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Jun 25 • 3:27 AM EDT • Sports • birminghamwatch.org
New polls show Americans’ complicated feelings about the country, 250 years on

More than three-quarters of Americans think the country’s founders would be disappointed with the US today, according to a Gallup poll released this week – one of several new surveys spotlighting the public’s complicated feelings about the nation’s legacy as it approaches its 250th anniversary.

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Jun 25 • 12:00 AM EDT • Politics • cnn.com
CMS projection: 90% of Americans will still have health insurance in 2034—when healthcare spending reaches $9T

Legislative changes, demographic shifts and growing demand will combine to drive national health spending to almost $9 trillion by 2034.

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Jun 24 • 10:38 PM EDT • Health • healthexec.com
Trump kicks off the Great American State Fair after musicians pulled out

A number of musical acts backed out of the event on the National Mall last month, concerned about being part of something that appeared political.

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Jun 24 • 10:26 PM EDT • Politics • nbcnews.com
High-Signal Publisher
World Cup crowds give downtown businesses a boost

A doughnut for breakfast? Not everyone knew! One Atlanta shop is introducing World Cup visitors to a sweet American tradition while building a future beyond the tournament. 🍩⚽

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Jun 24 • 10:22 PM EDT • Business • wsbtv.com
‘America is back’: Trump kicks off Great American State Fair with flyovers, patriotic National Mall speech

Trump kicks off the Great American State Fair on the National Mall, comparing his political movement to the American Revolution at the 250th anniversary.

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Jun 24 • 9:42 PM EDT • Politics • foxnews.com
Clay Aiken recalls 'huge blowup' with Kelly Ripa 20 years later: 'Probably the most catastrophic week of my life'

'American Idol' alum Clay Aiken is looking back on his 'huge blowup' with Kelly Ripa 20 years later: 'Probably the most catastrophic week of my life.'

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Jun 24 • 8:38 PM EDT • Entertainment • ew.com
The NHL Is Considering Bringing More Teams to Texas

The NHL has expanded to new areas in recent years, as the North American hockey league has brought teams to Las Vegas, Utah and Seattle. More expansion could be coming. But while hockey is known for its footprint in northern U.S. states and Canada, the league is considering bringing more of it to ...

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Jun 24 • 7:00 PM EDT • Sports • sports.yahoo.com
By Refusing to Sign a Bipartisan Housing Bill, Trump Made It Clear That He Doesn’t Care About Everyday Americans

What’s the president’s priority instead? Passing his voter-suppressing SAVE Act to keep his cronies in power.

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Jun 24 • 6:24 PM EDT • Politics • esquire.com
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Candidates backed by Vermont’s Bernie Sanders sweep House primaries in New York City

“The American people — in New York and all across this country — are sick and tired of status quo politics,” the independent U.S. senator said Wednesday.

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Jun 24 • 6:07 PM EDT • Politics • vtdigger.org
Marquette poll: Few Americans paying close attention to America 250

President Donald Trump’s approval rating stayed the same as May at 38%.

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Jun 24 • 5:29 PM EDT • Politics • spectrumnews1.com
DC Wrap: Trump lashes out over Iran vote; Great American State Fair begins

A look at the day's biggest stories in national politics

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Jun 24 • 5:21 PM EDT • Politics • spectrumlocalnews.com
DC Wrap: Trump lashes out over Iran vote; Great American State Fair begins

A look at the day's biggest stories in national politics

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Jun 24 • 5:21 PM EDT • Politics • spectrumlocalnews.com
Politics: What Donald Trump’s Defense Policy Means For Black Service Members

Black Americans serving in the U.S. military have long lived with a great contradiction. The country they’re fighting to protect is the same one that’s failed to serve and protect them.Despite this, Black Americans continue to enlist. There are over 350,000 Black active duty and select reserve members and more than 2.4 million Black veterans. That’s according to the Institute for Veterans and Military Families at Syracuse University.This year, Defense secretary Pete Hegseth has blocked or delayed the promotions of more than a dozen Black and female senior officers. He’s also dismissed several high-ranking Black and female officers, according to The Atlantic. This comes amid the second Trump administration’s aggressive rollback of programs and policies connected to diversity, equity and inclusion.Black military members have always battled discrimination. But for some, this is a step too far in the wrong direction. So, what does their future hold? And what does it mean for the U.S. military?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a.

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Jun 24 • 2:02 PM EDT • Politics • npr.org
High-Signal Publisher
Top supplements Americans use are shifting from multivitamins to targeted health fixes

Dietary supplements are an excellent way to fill gaps in our nutritional requirements. From vitamins and macronutrients to gut-health probiotics, dietary supplements have helped people address deficiencies. ...

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Jun 24 • 12:40 PM EDT • Health • medicalxpress.com
Affordability, not fraud, is why fewer Americans have health insurance

The “fraud, waste, and abuse” narrative has been seriously overworked, and does not fit the facts.

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Jun 24 • 11:30 AM EDT • Health • thehill.com
Towerhouse Signs Deals With Spate Of YouTube Content Brands Including Culture Genesis & ‘American Mayhem With Larry The Cable Guy’ Show

EXCLUSIVE: V10 Entertainment’s management business Towerhouse has opened its doors to a suite of YouTube content creators. Culture Genesis, the LPGA, MotoAmerica, Japan Racing Association (JRA), syndi...

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Jun 24 • 10:00 AM EDT • Entertainment • yahoo.com
Yankees Rivalry Roundup: Royals drop double-digit runs on Rays

Recapping how the Yankees’ top American League opponents fared on June 23rd.

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Jun 24 • 10:00 AM EDT • Sports • sports.yahoo.com
Follow the Money: Charting Private Health Insurance Cost Growth

Most Americans have health coverage through private (also called “commercial”) insurance. The prices for healthcare paid by private insurance are

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Jun 24 • 9:30 AM EDT • Health • tcf.org
The American Project Has Never Been Perfect. It’s Still Worth Fighting For.

Every Fourth of July my family goes on an adventure and this year we are going to Niagara Falls. The iconic falls in all their power and scale feel like an important destination for my kids’ formative years. Reflecting on 250 years As I prepare for the trip to this famed American tourist desti

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Jun 24 • 8:00 AM EDT • Science • blog.ucs.org
The ‘tech neck’ time bomb: why 43 million young Americans could cripple U.S. health care within a generation

A spine surgeon warns that smartphone addiction is quietly deforming the spines of Gen Z and Gen Alpha.

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Jun 24 • 7:30 AM EDT • Health • fortune.com
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