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Results for " mac " 6,259 found 🔀 AI-powered Shuffle

International Business Machines (IBM) Is A Top Stock In Billionaire Richard Chilton’s Filings

International Business Machines Corporation (NYSE:IBM) is one of the 10 Best Stocks to Buy According to Billionaire Richard Chilton. Technology giant International Business Machines Corporation (NYSE:IBM) made a key announcement recently when it announced its 0.7-nanometer chip manufacturing technology. This technology is the most advanced chip manufacturing technology in the world. International Business Machines Corporation […]

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Jun 28 • 6:33 AM EDT • Business • finance.yahoo.com
I overcame my fear of learning about AI and landed a Big Tech AI job

A product designer share how embracing her inner "mad scientist" and experimenting with AI helped her land a job at Adobe, with no formal background in machine learning.

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Jun 28 • 5:23 AM EDT • Business • businessinsider.com
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I overcame my fear of learning about AI and landed a Big Tech AI job

A product designer share how embracing her inner "mad scientist" and experimenting with AI helped her land a job at Adobe, with no formal background in machine learning.

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Jun 28 • 5:23 AM EDT • Science • businessinsider.com
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Padres outmatched by Dodgers with nine run inning

SAN DIEGO - Just when things started to look like the San Diego Padres found a resurgence after winning four in-a-row against two of the best teams in league, they run into a mack truck-like force called the Los Angeles Dodgers.

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Jun 27 • 11:51 PM EDT • Sports • sports.yahoo.com
Hurricanes Acquire Rights to John Carlson

It had been a long day. Some teams were using all of their allotted time, even in the later rounds to make their draft decisions. Then came Carolina, and time had expired while the world waited for them to make pick number 192 in the Draft. What happened? Eric Tulsky and company smacked everyone in […]

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Jun 27 • 10:00 PM EDT • Sports • sports.yahoo.com
MacBook Retail Sales Challenged By Apple Silicon Legacy

The extended lifespan of first-generation M1 MacBooks is impacting retail sales of the newer AI-focused MacBook Air and MacBook Pro laptops.

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Jun 27 • 7:15 PM EDT • Technology • forbes.com
Morgan Stanley Raises PT on International Business Machines (IBM) Stock

International Business Machines Corporation (NYSE:IBM) is one of the Best Cloud Computing Stocks to Buy According to Hedge Funds. On June 23, Morgan Stanley lifted its price objective on the company’s stock to $267 from $225, and maintained an “Equal Weight” rating on the shares. As per the analyst, Dell and HPE earnings demonstrate that the enterprise server demand […]

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Jun 27 • 6:18 PM EDT • Business • finance.yahoo.com
States seek to lower drug prices by targeting the companies that manage them for health plans

TOPEKA, Kan. — As consumers worry about medication costs, states are trying to lower drug prices by reining in big companies that oversee prescription coverage for health insurers. Some of those companies, called pharmacy benefit managers, also own pharmacies, and one of them, CVS, has spent millions of dollars fighting

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Jun 27 • 5:52 PM EDT • Health • triblive.com
3 million Americans have dropped Obamacare health coverage over past year, after Republicans let federal subsidies expire

KFF expects the total number of people in the government healthcare program to continue to decline throughout the year, potentially to a low of about 17.5 million from 19.2 million now.

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Jun 27 • 4:21 PM EDT • Health • fortune.com
Millions drop Obamacare health coverage after subsidies expire and costs rise

NEW YORK — About 3 million fewer people in the United States had Affordable Care Act health insurance plans in February compared with the same time...

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Jun 27 • 2:39 PM EDT • Health • post-gazette.com
Millions drop Obamacare health coverage after subsidies expire and costs rise

About 3 million fewer people in the United States had Affordable Care Act health insurance plans in February compared with the same time last year, according to new federal data. In the report releas...

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Jun 27 • 1:51 PM EDT • Health • yahoo.com
Millions drop Obamacare health plans after subsidies expire and costs rise

New federal figures show that about 3 million fewer people had Affordable Care Act health insurance plans in February compared with the same time last year.

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Jun 27 • 1:51 PM EDT • Health • apnews.com
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Millions drop Obamacare health coverage after subsidies expire and costs rise

New federal figures show that about 3 million fewer people had Affordable Care Act health insurance plans in February compared with the same time last year. The Department of Health and Human Services...

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Jun 27 • 1:51 PM EDT • Health • bigrapidsnews.com
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Millions drop Obamacare coverage after subsidies expire, costs rise

New federal figures show that about 3 million fewer people had Affordable Care Act health insurance plans in February compared with the same time last year

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Jun 27 • 1:51 PM EDT • Health • abcnews.com
Scalpers Are Already Flipping Steam Machine Reservations On eBay For $2,700–$2,900, Roughly Double Valve’s Price

Reservations for the Steam Machine are listed on eBay for up to $2,899, nearly triple its official price of $1,400, amid widespread scalping efforts

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Jun 27 • 9:16 AM EDT • Technology • wccftech.com
The Extremely Online Senate Race Testing Democrats’ Midterm Strategy

In 2026, winning an election might mean winning the most attention online.

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Jun 27 • 7:00 AM EDT • Politics • politico.com
Driving A New Ford Mustang Mach-E After 5 Years Feels So Much Better

The 2026 Ford Mustang Mach-E isn't drastically different from its original 2021 version, but small improvements and a price dip make it a better EV purchase.

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Jun 27 • 6:15 AM EDT • Technology • forbes.com
Fallout from USMNT loss to Turkey and previewing the Mbappe-Haaland clash

On today’s show, we look back at the United States’ final group stage match against Turkey and evaluate their readiness for the Round of 32. Manchester City insider Sam Lee joins us to preview the tournament’s first true superstar heavyweight clash as Kylian Mbappe and France square off against Erling Haaland and Norway in a battle for Group I supremacy. Plus, The Athletic’s Jay Harris is back in the studio to break down the latest bracketology, advancement percentages, and qualification permutations for Groups G, H, and I using The Athletic’s World Cup Tracker.

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Jun 27 • 6:00 AM EDT • Sports • nytimes.com
Scalpers List Steam Machine Reservations at $1,700+

Following a brief reservation period, prospective buyers of the Valve Steam Machine started reporting on June 26 that they had begun to receive reservation confirmation emails for the new hybrid console. However, on the same day, and almost predictably, apparent scalpers listed Steam Machine units o...

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Jun 26 • 8:37 PM EDT • Technology • techpowerup.com
AI-generated knockoffs of Joanna Stern’s book keep appearing on Apple Books

In a video published on YouTube Shorts today, Joanna Stern called out Apple over AI-generated knockoffs of her book that continue to appear on Apple Books.

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Jun 26 • 6:36 PM EDT • Technology • 9to5mac.com
Lawmakers say White House demolition debris at East Potomac Park poses health risk

Democratic lawmakers are urging the Trump administration to remove demolition debris from East Potomac Park Golf Course, citing health concerns, while the administration says the site poses no public health risk.

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Jun 26 • 5:09 PM EDT • Health • wtop.com
Tired of long waits? Mochi Health offers virtual care starting at $39

Mochi Health now offers full-service virtual care with unlimited visits, flexible pharmacy options and plans starting as low as $39.

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Jun 26 • 5:06 PM EDT • Health • usatoday.com
Apple Loop: iPhone 18 Pro Release Date, Hidden iOS 27 Features, iPhone Air 2 Details

This week’s Apple headlines: iPhone 18 Pro price and release date, hidden iOS 27 features, iPhone Air 2 specs, unexpected Mac and iPad price rises, how Apple wins AI and more...

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Jun 26 • 5:03 PM EDT • Technology • forbes.com
iPhone 18 Pro and Pro Max May See $200 Price Increase

Apple's iPhone 18 Pro models could be up to $200 more expensive, according to a prediction from analytics firm IDC. IDC expected Apple to raise iPhone 18 prices, but prior to yesterday's Mac and iPad price hike, the prediction was a $100 increase for the 18 Pro and Pro Max, and a $50 increase for the base models. IDC Senior Director of Data & Analytics Nabila Popal says the magnitude of the Mac and iPad price increase points to even higher iPhone 18 prices.

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Jun 26 • 3:17 PM EDT • Technology • macrumors.com
MacBook Ultra and new MacBook Pro both launching this fall, per rumors

Apple’s high-end MacBook plans are coming into focus after recent Bloomberg reports, including MacBook Ultra and a new M6 MacBook Pro.

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Jun 26 • 3:03 PM EDT • Technology • 9to5mac.com
“The Cheaper the Better,” Says Valve About its Steam Machine Pricing, but Don’t Expect a Price Decrease “Any Time Soon”

"The cheaper the better" is Valve's official line for how it would like to price the Steam Machine, but don't expect it to happen soon.

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Jun 26 • 1:44 PM EDT • Technology • wccftech.com
Some In Silicon Valley Want To Build A Machine God: Here's What Business Leaders Should Build Instead.

What young people need to become capable, grounded adults is not a faster model release.

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Jun 26 • 1:06 PM EDT • Business • forbes.com
2027 iPhone 18 and iPhone 18e to Get 9GB RAM and A20 Chip

The lower-end iPhone 18 models set to launch in spring 2027 will feature 9GB DRAM, up from 8GB, according to Apple analyst Ming-Chi Kuo. Kuo says the A20 chip Apple plans to use for the devices will have 1.5GB x 6 dies for a total of 9GB RAM, instead of 2GB x 4 dies as the current lower-end iPhone 17 models use. By lower-end iPhones, Kuo is likely referencing the iPhone 18 and the iPhone 18e, both of which are rumored to be coming around March or April of 2027.

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Jun 26 • 12:57 PM EDT • Technology • macrumors.com
New iPhone 18 specs report raises big question of iOS 27 limitations

Apple’s base model iPhone 18 might not get as much RAM as expected—raising questions about support for iOS 27’s most demanding features.

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Jun 26 • 12:57 PM EDT • Technology • 9to5mac.com
Science Can Fully Explain Consciousness? By 326 Theories…

It’s supposed to be a given that machines or brain organoids might be conscious despite not knowing what that is or how it works — but preborn children can’t be…

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Jun 26 • 12:33 PM EDT • Science • mindmatters.ai
Apple's OLED 'MacBook Ultra' Will Stick With M5 Pro and M5 Max Chips

Apple's upcoming high-end MacBook model featuring an OLED touchscreen display will use the company's current M5 Pro and M5 Max chips, according to Bloomberg's Mark Gurman. The new, top-of-the-line device will launch "between late this year and early next year," Gurman said, adopting the existing high-end Apple silicon chips rather than next-generation M6 versions.

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Jun 26 • 11:35 AM EDT • Technology • macrumors.com
New iPhone Ultra report has new pricing and release timing info

Apple’s highly anticipated foldable iPhone is launching this fall, but a new report today claims you might have to wait...

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Jun 26 • 11:11 AM EDT • Technology • 9to5mac.com
Apple’s Touch MacBook to Use M5 Pro and Max Chips, With M7 Models to Follow

Apple Inc.’s first-ever touch-screen laptop will rely on the company’s current high-end M5 chips, rather than next-generation silicon, though the company is working on a follow-up model with future M7 processors.

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Jun 26 • 11:08 AM EDT • Technology • bloomberg.com
iPhone 18 Pro and Foldable iPhone Tipped to Get Price Hikes Too

Apple's iPhone 18 Pro lineup and its first foldable iPhone will launch at higher prices than originally predicted this September, according to several known Chinese leakers.

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Jun 26 • 10:14 AM EDT • Technology • macrumors.com
Framework lowers Laptop 13 Pro prices in response to Apple’s Mac price hikes

Framework has lowered some Laptop 13 Pro prices after switching to ADATA Gen 5 SSDs. Existing pre-orders with older Gen 5 SSD options will also be updated.

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Jun 26 • 8:09 AM EDT • Technology • videocardz.com
Taylor Launches New Bachelor's Degree in AI and Machine Learning

Taylor University is launching a Bachelor of Science in Artificial Intelligence and Machine Learning, building on four decades of AI expertise.

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Jun 26 • 8:00 AM EDT • Science • taylor.edu
Here's How The New Xbox Prices Compare To PS5, Switch 2 & Steam Machine

Going live as of August 2026

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Jun 26 • 6:00 AM EDT • Technology • purexbox.com
Valve Would "Love to Make the Steam Machine More Affordable" - Just Don't Expect It "Any Time Soon"

If memory prices go down - and that's a big if.

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Jun 26 • 5:56 AM EDT • Technology • digitalfoundry.net
Best Prime Day laptop deals: Save up to $970 on MacBooks, Windows PCs

Laptops are very expensive these days. These discounts help.

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Jun 26 • 2:24 AM EDT • Technology • mashable.com
How an Iowa junior college became a sports giant

DMACC athletic programs are quietly dominating through coaching and player performance

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Jun 26 • 12:14 AM EDT • Sports • kcci.com
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It's Xbox's turn (again), as console prices keep going up

Microsoft announced a price hike for the Xbox Series consoles today, the third in little over a year. Effective August 1, the Xbox Series S, which launched in 2020 for $300, will cost $500 in the U.S. The Xbox Series X, which launched in 2020 at $500, will go for $800. This follows a round of PlayStation 5 price increases from Sony this spring, and a slow-motion increase for Nintendo’s Switch 2, which will kick in in the U.S. in September. (Mind you, there were also eight video game industry price hikes in six months of 2025). The chart up top shows the sudden ascent of console prices over the past year, a sudden surge in an already unusual hardware generation. Prices had been flat for years, now “up” is the new “flat.” Game console prices used to go down across the length of a console generation, but not this time around. Microsoft’s explanation for the new price hike today: We hoped another price increase would not be necessary, and we have spent the last several months working with suppliers on options. Unfortunately, console storage and memory prices have increased by more than 2.5x and we expect another doubling by the fall of 2027. The entire consumer electronics industry is struggling with the current components crisis, but the effects are particularly hard on consoles. Unlike phones, computers, speakers, and other consumer devices, consoles are typically not sold at a profit, but instead for less than they cost to make. This is an issue well beyond game consoles. Apple announced price hikes on its computers and tablets today as well. Game File is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe Item 2: Brutal Bungie cuts Bungie laid off “most” of its Destiny development team and some developers who worked on Marathon, the newest game from the struggling Sony-owned studio. A WARN notice issued by Sony to Washington State, where Bungie is based, tallied cuts impacting 292 workers, effective next month. That’s strictly for Bungie/Sony jobs in Washington and wouldn’t account for any elsewhere. The video I clipped below shows the redacted list of Bungie cuts filed to Washington State officials. As you’ll see, I had to scroll for a while… In a note emailed to PlayStation workers and published online, PlayStation game studios chief Hermen Hulst offered the following explanation for these latest cuts at Bungie: This is painful news, especially for talented colleagues whose roles have been eliminated. This decision was made only after extensive discussion and careful consideration, and I want to provide some context on how we arrived here. Over the past several months, together with Bungie leadership, we reviewed the studio’s long-term direction, development priorities, resource needs, and role within our broader portfolio strategy. We explored multiple alternatives before concluding that a reduction was necessary to align the studio’s resources with its current priorities and long-term goals. In 2022, Sony bought Bungie for $3.7 billion. The studio’s marquee game, the multiplayer live service shooter Destiny 2 was losing popularity at the time. Its next game Marathon, released earlier this year, has been well-reviewed but had a slow start. Bungie is renowned for making great shooter games, and Destiny fans have mourned the wind-down of Destiny 2. They’ve also expressed bewilderment over reports that Destiny 3 is not, per Bloomberg, immediately in the cards.

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Jun 25 • 8:21 PM EDT • Technology • gamefile.news
This Is Probably Your Last Chance to Buy a Cheap MacBook for a While

Apple has dramatically jacked up the price of MacBooks, making the current Prime Day pricing that much more enticing.

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Jun 25 • 8:07 PM EDT • Technology • wired.com
M6 MacBook Pro Expected This Year With Apple's First 2nm Chip

Apple could launch an updated base model 14-inch MacBook Pro with an M6 chip as soon as this year, reports Bloomberg. There could also be M6 chip updates for the Mac mini, iMac, and MacBook Air, but Apple is testing an M6 MacBook Pro. Apple plans to introduce the M6 in late 2026, and for the first time, it will be a standalone chip. Apple is not working on M6 Pro or M6 Max chips, and will hold off on higher-end chip options until the M7 series launches in 2027.

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Jun 25 • 7:21 PM EDT • Technology • macrumors.com
Valve Deletes 4K 60FPS Claim From Steam Page After Reviews

Some have struggled to hit consistently high framerates on the new hardware

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Jun 25 • 7:00 PM EDT • Technology • kotaku.com
Monkey Business: Wild rhesus macaque spotted at Mount Dora hotel

A wild rhesus macaque was spotted at the historic Lakeside Inn in Mount Dora, Florida, spending about 45 minutes roaming the property and attracting attention from guests and staff. The hotel and local businesses responded with humorous, monkey-themed social media content, engaging the community. Wildlife officials cautioned the public not to approach or feed wild monkeys due to potential health risks and encouraged reporting sightings to authorities. The monkey has not returned to the hotel but has been seen elsewhere in downtown Mount Dora.

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Jun 25 • 6:12 PM EDT • Business • clickorlando.com
Yearslong Resident Evil mystery solved: Kyle MacLachlan revealed to be Jill Valentine's 'boyfriend'

Twin Peaks star has ties to STARS

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Jun 25 • 5:50 PM EDT • Technology • polygon.com
M5 Ultra Mac Studio Could Launch in 2026 With Up to 768GB of RAM

Despite price increases across the Mac line, Apple is still planning to release a new Mac Studio as soon as this year, reports Bloomberg. Apple plans to introduce a new M5 Ultra chip as the final option in the M5 family before it transitions to the M6, M7, M7 Pro, and M7 Max. The M5 Ultra will come in a new version of the Mac Studio, which hasn't been updated since March 2025.

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Jun 25 • 5:30 PM EDT • Technology • macrumors.com
Valve Quietly Walks Back Steam Machine 4K 60 FPS Performance Claims

Valve's Steam Machine has earned more than its fair share of skeptics, thanks to performance claims and more recently its unfortunate pricing. More recently, though, Valve has seemingly taken some of this criticism to heart and silently changed some of those performance claims on the Steam Machine p...

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Jun 25 • 5:25 PM EDT • Technology • techpowerup.com
Making Our Own Luck

We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.

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Jun 25 • 4:48 PM EDT • Science • goodscience.substack.com
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Scientists measure hidden quantum forces that could power a new generation of pharmaceutical drugs

It's one thing to design a pharmaceutical drug. It's another to know if and why it actually works; not on paper or in a computer model, but inside the chaotic world of living systems, where proteins twist ...

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Jun 25 • 4:20 PM EDT • Science • phys.org
Following IAM Union Advocacy, Kansas PERB Orders Count of Timely Cast Ballots in KU Health System Pharmacy Technician Union Election

KANSAS CITY, Kan. — Following weeks of advocacy from the IAM Union, Pharmacy Technicians, elected officials and community supporters, the Kansas Public Employee Relations Board (PERB) has ruled that 37 previously uncounted ballots will be included in the final tally of the recent union representation election involving Pharmacy Technicians at the University of Kansas (KU)

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Jun 25 • 4:19 PM EDT • Health • goiam.org
Valve quietly changes Steam Machine 4K claim: 4K 60 FPS becomes “up to 4K”

Valve has changed the Steam Machine 4K claim. The page now says “up to 4K” with FSR 4.1 instead of 4K 60 FPS with FSR.

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Jun 25 • 3:46 PM EDT • Technology • videocardz.com
Microsoft lifts price of Xbox consoles due to soaring component costs

Microsoft said it's increasing the price of Xbox game consoles after Apple announced price hikes for MacBooks and iPads.

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Jun 25 • 1:34 PM EDT • Technology • cnbc.com
Major blow for MacBook Ultra: Apple said to cancel M6 Pro and M6 Max

The Apple MacBook Ultra will either be released with the older Apple M5 Max, or its launch will be significantly delayed. This is because Apple is said to have halted development of the Apple M6 Pro and M6 Max in order to focus on the M7 series instead, which is expected to offer significantly stronger AI performance.

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Jun 25 • 1:20 PM EDT • Technology • notebookcheck.net
Q&A: What does science say about plants as medicine?

Plants have always played an integral role in traditional medicine and healing practices, according to Kent Vrana, Elliot S. Vesell Professor of Pharmacology at Penn State College of Medicine…

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Jun 25 • 1:12 PM EDT • Science • pennstatehealthnews.org
Apple to Skip High-End M6 Mac Chips in Favor of AI-Focused M7 Line

Apple Inc. is making one of the biggest-ever changes to its Mac silicon strategy, preparing to jump ahead to a new artificial intelligence-focused chip generation for its next top-end processors.

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Jun 25 • 12:35 PM EDT • Technology • bloomberg.com
Notion shutting down its AI-powered email client, including Mac and iOS apps

Last year, Notion expanded its productivity suite to include Notion Mail, an AI-powered email client. Today, the company announced that...

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Jun 25 • 12:25 PM EDT • Technology • 9to5mac.com
Apple has new ‘iRing’ wearable product in the works, says leaker

Leaker Kosutami says an Apple ‘iRing’ is now in development to compete with other health trackers like Oura’s smart ring.

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Jun 25 • 10:44 AM EDT • Technology • 9to5mac.com
Scientists measure hidden quantum forces that could power a new generation of pharmaceutical drugs

Researchers invent a laser technique that reveals the hidden forces shaping proteins, advancing a future of precision medicine engineered with quantum precision.

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Jun 25 • 10:24 AM EDT • Science • stories.tamu.edu
Apple raises Mac and iPad prices by as much as 25%

Apple CEO Tim Cook had earlier warned of price increases due to the memory chip shortage.

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Jun 25 • 9:15 AM EDT • Business • businessinsider.com
NJ Legislators Push for End to Corporate Money in Politics

NJ Legislators Push for End to Corporate Money in Politics New Legislation Would Redefine “Corporation” Under State Law to Disallow Political Spending SUMMIT, N.J.—Assemblymembers Andrew Macurdy, Chigozie Onyema, and Maureen Rowan today announced a bill that would bring an end to corporate spending on politics in New Jersey. The bill alters the definition of “corporation”[...]

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Jun 25 • 8:35 AM EDT • Politics • insidernj.com
Apple Store is down: 'We’re making updates,' Apple says

Apple’s Online Store is down this morning, with the company saying it’s “making updates to the Apple Store.” The Apple...

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Jun 25 • 7:56 AM EDT • Technology • 9to5mac.com
iPhone Ultra 2 already given go-ahead, iPhone Air 3 not, says leaker

We may still be waiting for the launch of the iPhone Ultra, but a leaker with a decent track record...

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Jun 25 • 7:14 AM EDT • Technology • 9to5mac.com
NASA rover finds record-breaking trove of complex organic molecules on Mars

Data from NASA’s Perseverance rover confirms the presence of macromolecular carbon on Mars – another potential piece of the puzzle in the search for life.

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Jun 25 • 5:30 AM EDT • Science • livescience.com
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iPhone Ultra 2 Gets Green Light for Development, Says Leaker

Apple's second-generation foldable iPhone has officially been given the go-ahead for development, a prominent Chinese leaker claimed today. In a post on Weibo, the account known as Digital Chat Station said that the "iPhone Ultra 2 project" has been formally approved, and that the second book-style device will likely use the same display as the first-generation model expected later this year.

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Jun 25 • 5:27 AM EDT • Technology • macrumors.com
America’s Friendship Recession Has Become a Startup Opportunity

A new “connection economy” is selling courses, clubs and confidence bootcamps to socially isolated adults, but scaling intimacy remains a challenge.

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Jun 25 • 5:15 AM EDT • Business • bloomberg.com
Mackenzie eyes UFC dream after Cage Warriors deal

Welsh bantamweight Ieuan Mackenzie is aiming to reach the UFC after signing a five-fight deal with Cage Warriors.

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Jun 25 • 4:42 AM EDT • Sports • sports.yahoo.com
Best Prime Day laptop deals: Save up to $970 on MacBooks, Windows PCs

Laptops are very expensive these days. These discounts help.

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Jun 25 • 4:31 AM EDT • Technology • mashable.com
Scientists have just unlocked the secrets of an ancient scroll torched by Mount Vesuvius

After a centuries-long struggle, scholars managed to read five feet of text, using machine-learning methods they hope can unlock further discoveries.

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Jun 25 • 4:30 AM EDT • Science • washingtonpost.com
How is Derry City's new pitch 'World Cup standard'?

Ahead of Friday's first game back at the Brandywell, BBC Sport learns how a giant sewing machine has helped put Derry City's new hybrid pitch together.

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Jun 25 • 3:58 AM EDT • Sports • sports.yahoo.com
'Need each other': Macron hosts Meloni after Trump rift

One of Europe's most prominent right-wing leaders will arrive on the French Riviera for her first bilateral summit with Macron, fresh from her fallout with Donald Trump

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Jun 24 • 10:25 PM EDT • Politics • euractiv.com
Latest COVID booster may offer bonus health benefit, study suggests

The latest COVID-19 vaccine (2024-2025) has been linked to fewer serious heart-related events among U.S. veterans. New research confirmed a small reduction in COVID-related cardiovascular events, or COVID-19-associated MACE, due to the vaccine.

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Jun 24 • 9:53 PM EDT • Health • foxnews.com
iOS 27 Home App: 10+ New HomeKit Features

Apple updated the Home app with some useful new features that rely on Apple Intelligence. The updates improve the way HomeKit Secure Video cameras work on Apple's HomeKit platform. Apple Intelligence Summaries The Home app generates written summaries for motion alerts and what's detected, using AI to determine what's been recorded.

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Jun 24 • 7:15 PM EDT • Technology • macrumors.com
Valve clarifies: all Steam Machines, for now, will ship with one 16GB stick of RAM.

In an interview with Gamers Nexus, Valve had said that the PCs would ship with either one 16GB stick of RAM or two 8GB sticks of RAM. “We misspoke here - all units will actually have one 16GB stick of RAM,” the company says in a follow-up statement to the channel. “It’s possible that this might change in future builds, but the units that customers are currently signing up for will all come with one 16GB stick of RAM.” [Media: https://youtu.be/glXA3ObwSwQ?si=QGmDWmVfbMiONxLd&t=109]

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Jun 24 • 6:13 PM EDT • Technology • theverge.com
Apple tells Siri AI to clearly refuse requests to summarize URLs

A new rule added to Siri AI’s system prompt in iOS 27 beta 2 changes how it should handle requests involving extracting or summarizing content behind a URL.

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Jun 24 • 5:17 PM EDT • Technology • 9to5mac.com
My Music Row Story: Big Machine Records/Nashville Harbor Records & Entertainment’s Allison Jones

With over 35 years of experience in the music industry, Allison Jones serves as EVP of A&R at [...]

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Jun 24 • 4:36 PM EDT • Entertainment • musicrow.com
Steam Machine Sells Out in Japan Despite Woeful Pricing

As was the case with the Steam Deck, Valve is selling the Steam Machine via Komodo Station, an Asian reseller that serves much of South-East Asia, and as a result, it skips the reservation and lottery system that is currently in place on Valve's own Steam Store. While this doesn't combat issues like...

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Jun 24 • 4:01 PM EDT • Technology • techpowerup.com
Fox News Poll: Looking ahead to America's 250th anniversary

A Fox News survey finds 53% of voters are proud of America and 54% believe the best days are ahead as the nation nears its 250th anniversary.

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Jun 24 • 3:28 PM EDT • Politics • foxnews.com
Pat Ryan’s insurance firm shuffles leadership at RT Specialty unit

CEO Ed McCormack will remain with company as vice chair of RT Specialty through 2027.

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Jun 24 • 2:04 PM EDT • Business • chicagobusiness.com
This health data provider could benefit as AI reshapes drug research

Harvey Stober, senior equity analyst and correspondent at CNBC, explains why this healthcare company could benefit from artificial intelligence reshaping the drug industry thanks to its treasure trove of data.

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Jun 24 • 1:38 PM EDT • Health • cnbc.com
Top supplements Americans use are shifting from multivitamins to targeted health fixes

Dietary supplements are an excellent way to fill gaps in our nutritional requirements. From vitamins and macronutrients to gut-health probiotics, dietary supplements have helped people address deficiencies. ...

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Jun 24 • 12:40 PM EDT • Health • medicalxpress.com
New MacBook Air M3 Is Now Cheaper Than Basic Windows Laptops, Amazon Goes 40% Off and Apple Keeps Its Full Warranty

At this price, the MacBook Air M3 now costs less than Windows laptops that lose to it on battery, display, and build quality.

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Jun 24 • 10:35 AM EDT • Technology • gizmodo.com
Foldable iPhone 'Ultra' Set for Production in July Despite Hinge Issues

Apple's rumored foldable iPhone "Ultra" is expected to begin mass production at the end of July, according to a new report by The Elec. Although some recent reports suggested the book-style device could be delayed due to hinge-related issues, the Korean outlet's sources indicate that Apple is still targeting a September launch as planned.

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Jun 24 • 9:56 AM EDT • Technology • macrumors.com
iPhone Ultra 3D-printed hinge problems reportedly solved

Talk of a delayed launch for the upcoming iPhone Ultra now seems to have faded away, with all recent reports...

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Jun 24 • 9:05 AM EDT • Technology • 9to5mac.com
Prime Day 2026: Top Savings on Anker, Beats, TVs, and More Accessories

Earlier this week we highlighted some of the best Apple-related product discounts that you can find on Amazon during Prime Day, and now we're focusing on third-party accessory markdowns during the event. In this article you'll find all the best accessories for charging, smart homes, smartphones, and more. Note: MacRumors is an affiliate partner with some of these vendors. When you click a link and make a purchase, we may receive a small payment, which helps us keep the site running.

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Jun 24 • 8:21 AM EDT • Technology • macrumors.com
Valve Confirms You Can Build Your Own Steam Machine

Support for NVIDIA hardware is also on the way.

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Jun 24 • 7:18 AM EDT • Technology • 80.lv
Valve admits Steam Machine is "more expensive" than it hoped

The PC giant is non-commital on whether the console's price will come down in the future if hardware costs reduce

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Jun 24 • 5:48 AM EDT • Technology • gamesindustry.biz
Braves blow another one in 7-6 loss to Padres

A wild night at Petco Park was capped off by a walk-off single by way of Manny Machado as the Braves fell to the Padres, 7-6, in 10 innings. This is a bad baseball team at the moment. The second inning was a doozy for both sides. The Braves loaded the bases and cashed in […]

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Jun 24 • 12:56 AM EDT • Sports • sports.yahoo.com
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President Trump tells politician to 'run up here' during speech

President Donald Trump introduces Pennsylvania Congressman Ryan Mackenzie at a rally.

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Jun 23 • 6:28 PM EDT • Politics • foxnews.com
Florida Attorney General Issues Subpoena to CVS Health in Pharmacy Probe

Florida’s attorney general says he is examining whether CVS’s pharmacy benefit manager steers patients to its own pharmacies.

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Jun 23 • 5:33 PM EDT • Health • barrons.com
Apple releases new AirPods beta firmware, including first build for AirPods Max 2

Following the release of iOS 27 beta 2, Apple is rolling out the first firmware beta for AirPods Max 2, alongside second beta builds for other supported AirPods models.

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Jun 23 • 5:32 PM EDT • Technology • 9to5mac.com
Trump touts falling oil prices, economy at Pennsylvania rally

The president spoke at a Mack Trucks factory in Macungie on Tuesday

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Jun 23 • 5:18 PM EDT • Politics • spectrumlocalnews.com
Trump touts falling oil prices, economy at Pennsylvania rally

The president spoke at a Mack Trucks factory in Macungie on Tuesday

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Jun 23 • 5:18 PM EDT • Politics • spectrumlocalnews.com
Trump touts falling oil prices, economy at Pennsylvania rally

The president spoke at a Mack Trucks factory in Macungie on Tuesday

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Jun 23 • 5:18 PM EDT • Politics • spectrumlocalnews.com
Apple’s 2026 OLED lineup will reportedly rely entirely on Samsung and LG

Samsung and LG have reportedly begun mass production of OLED panels for Apple’s 2026 product lineup. Here are the details.

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Jun 23 • 4:56 PM EDT • Technology • 9to5mac.com
The Steam Machine's Companion Cube case is big, expensive, and based on a 19-year-old joke, so I hate how well-made it is

The Steam Machine provides a chance to get reacquainted with the Companion Cube, courtesy of Dbrand's pricey (though admittedly finely designed) case.

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Jun 23 • 3:44 PM EDT • Technology • rockpapershotgun.com
iOS 27 Wallet App Gets 7 New Features

Apple is making more of an effort to turn the iPhone into a physical wallet replacement in iOS 27, and there are several upgrades to the Wallet app. Pass Upgrades Apple upgraded airline boarding passes in the Wallet app with iOS 26, and in iOS 27, upgrades are coming to additional types of passes.

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Jun 23 • 3:32 PM EDT • Technology • macrumors.com
Florida AG launches investigation into CVS Health over pharmacy competition concerns

Florida Attorney General James Uthmeier issued a Civil Investigative Demand to CVS Health Corporation, the owner of the Caremark pharmacy benefit manager and hundreds of CVS retail pharmacies across the state.

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Jun 23 • 3:20 PM EDT • Health • news4jax.com
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iPhone 18 Pro: Three new features that already have me excited

iPhone 18 Pro is still a few months away, but out of the rumored new features so far, there are three upgrades I’m especially excited about.

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Jun 23 • 2:45 PM EDT • Technology • 9to5mac.com
Steam Machine is 'more expensive' than even Valve wanted it to be

The PC gaming giant knows some fans won't be able to afford its new system, but Valve didn't want things to work out this way

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Jun 23 • 2:33 PM EDT • Technology • polygon.com