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Sandy shores and serious business: Palomar takes on InsuranceFest 2026

The industry’s best minds are gathering in one location

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May 12 • 9:17 AM EDT • Business • insurancebusinessmag.com
Scientists reversed biological age in older adults with a 4-week diet change

A four-week diet change was enough to make some older adults appear biologically younger in a new University of Sydney study. Participants who reduced fat intake or shifted toward more plant-based protein showed improvements in key health biomarkers tied to aging. The strongest results came from a lower-fat, higher-carb diet, while people eating closer to their usual diets saw almost no change.

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May 12 • 8:00 AM EDT • Science • sciencedaily.com
Henrico power washing business opening its first out-of-state office

“It’s gotten to a point where it doesn’t make sense for us to drive 14 hours for these projects,” said owner Omar Elshami, who also owns an ice cream shop in Carytown.

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May 12 • 2:01 AM EDT • Business • richmondbizsense.com
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New York Jets Flight Connections 05/10/26

Happy Sunday, Jets fans, and Happy Mother’s Day! Below are your weekend Jets links. Jack Bell – Rookie Minicamp Notebook | Kenyon Sadiq on Jets’ Tight Ends: ‘Possibilities Are Endless’ Eric Allen – The ‘Insane’ NFL Reunion of Indiana’s Omar Cooper Jr. and D’Angelo Ponds Rich Cimini – Jets QB Klubnik unshaken by fall in […]

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May 10 • 7:00 AM EDT • Sports • sports.yahoo.com
LIVE: ALLEGRI'S PRESS CONFERENCE

Back at San Siro to get back to winning ways and kick-start our run again. AC Milan v Atalanta is our fixture for Matchday 36 of Serie A, and on the eve of the game, Coach Allegri’s customary press ...

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May 9 • 5:47 AM EDT • Sports • sports.yahoo.com
Man who sprayed vinegar at Rep. Omar during town hall pleads guilty to assault

Anthony Kazmierczak, 55, is awaiting sentencing

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May 8 • 10:01 AM EDT • Politics • spectrumlocalnews.com
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‘Dream becomes real’: FAMU business school gets $300K for scholarships

FAMU's\u00a0spring commencement\u00a0speakers\u00a0did\u00a0more than address graduating students – they also\u00a0made six-figure donations\u00a0to one of its flagship schools.

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May 7 • 11:00 AM EDT • Business • tallahassee.com
How business leaders see AI transforming work

From boosting productivity to reshaping entire business models, artificial intelligence is becoming a defining force across industries. Here’s how business leaders assess its impact at the Milken Institute Global Conference 2026 in Beverly Hills, Los Angeles.

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May 4 • 5:12 PM EDT • Business • cnbc.com
Mending Hearts: Danny Romary Turns Struggle Into Service

Discover the inspiring story of Danny, a cardiac survivor who returned to CaroMont Health as a Mended Hearts® volunteer. This story explores the powerful role of peer-to-peer support in heart surgery recovery, highlighting how hope and human connection lead to better clinical outcomes, shorter recovery times, and reduced anxiety. Learn how the Mended Hearts® national nonprofit partners with CaroMont Health to provide emotional support that goes beyond the stethoscope.

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May 3 • 8:00 PM EDT • Health • caromonthealth.org
Update on Keyport Sanitary Landfill at Aeromarine Industrial Park

Update on Keyport Sanitary Landfill at Aeromarine Industrial Park

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Apr 30 • 8:47 PM EDT • Health • nj.gov
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New study suggests coffee supports gut health and mood

Key Takeaways:Coffee might support both gut health and mood, with recent study participants showing lower stress, depression, and more beneficial gut bacteria.OSF gastroenterologist Omar Khokhar says effects vary by individual and coffee type, and the study only shows a correlation, not proof of cause.Moderation and personal tolerance matter mos...

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Apr 30 • 9:00 AM EDT • Health • newsroom.osfhealthcare.org
Jets take edge rusher David Bailey over Ohio State's Arvell Reese with No. 2 pick, then take Oregon TE Kenyon Sadiq, Indiana WR Omar Cooper Jr. in 1st round
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Apr 23 • 8:39 PM EDT • Sports • sports.yahoo.com
MN lawmaker takes action to get answers on Omar's alleged fraud ties after she skips key hearing: 'Ghosted us'

Rep. Ilhan Omar faces scrutiny after skipping a Minnesota hearing on her potential links to the massive Feeding Our Future pandemic fraud probe.

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Apr 23 • 9:04 AM EDT • Politics • foxnews.com
Cedarville Sports Practicum A Video Learning Lab
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Apr 20 • 2:39 PM EDT • Sports • cedars.cedarville.edu
Moss for ProMarket: How the Professionalization of College Sports Changed Who Wins

The new model in the United States of paying college student athletes emerged from a complex settlement in the 2025 House v. NCAA private antitrust class action. The settlement supercharged Division I schools’ incentives to fund high-revenue sports programs because they need to pay for millions of dollars in required revenue-sharing with their student athletes. The prospect […]

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Apr 20 • 10:57 AM EDT • Sports • progressivepolicy.org
How the Professionalization of College Sports Changed Who Wins

The House v. NCAA private antitrust settlement professionalized collegiate sports by requiring colleges and universities to compensate student athletes. The case has changed the economics of college sports, pushing schools to spend big to pay for top athletes to field teams that compete for championships. New research from the Progressive Policy Institute finds that although the new model has narrowed success to the top programs, the ability for schools to pay for success has now been mostly priced in, writes Diana L. Moss.

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Apr 20 • 6:00 AM EDT • Sports • promarket.org
Exclusive | Ilhan Omar Says She Isn’t a Multimillionaire, Blames Accounting Error

The Minnesota Democratic congresswoman, facing potential investigations pushed by President Trump and House Republicans, said she isn’t as wealthy as documents she previously submitted to Congress suggest.

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Apr 17 • 6:19 PM EDT • Politics • wsj.com
NASA Begins Implementation for ESA’s Rosalind Franklin Mission to Mars

NASA has given approval for the agency’s Rosalind Franklin Support and Augmentation (ROSA) project to begin implementation, underscoring the agency’s

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Apr 16 • 12:18 PM EDT • Science • science.nasa.gov
The 5 key biomarkers that can tell you how well you're aging — the most crucial is the most overlooked
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Apr 16 • 6:00 AM EDT • Health • nypost.com
Re:Cognition Health Delivers Landmark International Clinical Trial to Explore Whether a Simple Finger-prick Blood-based Biomarker Test Can Provide Earlier Alzheimer's Diagnosis

Re:Cognition Health, a global leader in new treatments for Alzheimer's Disease, is delivering an international clinical trial to evaluate whether a simple finger-prick blood test can revolutionize how Alzheimer's disease is diagnosed. Compared with the current invasive and expensive diagnostic methods, this approach could provide a scalable solution for an earlier, easier, more accurate, affordable, and accessible diagnostic method. Re:Cognition Health will help enroll approximately 1,000 partic

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Apr 15 • 11:15 AM EDT • Health • finance.yahoo.com
How aggressive breast cancer turns off the immune system

Researchers are launching a new project to crack the mystery of aggressive breast cancer, where predicting disease progression remains a major hurdle. By studying how tumors interact with and suppress the immune system, scientists aim to identify new biomarkers that reveal how the cancer evolves. Using real patient samples, the team hopes to turn earlier discoveries into practical clinical tools. The goal: more precise, personalized treatments that can outsmart even the most dangerous tumors.

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Apr 11 • 8:00 PM EDT • Science • sciencedaily.com
Omar Cooper Jr. NFL Draft Profile

Doug watches the college film to assess Omar Cooper Jr.'s strengths and weaknesses as well as what it likely means for his NFL future.

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Apr 11 • 4:01 AM EDT • Sports • sports.yahoo.com
Red Sea Military Hub Djibouti’s President Extends 27-Year Rule

Djiboutian President Ismaïl Omar Guelleh won elections by a landslide, extending his 27-year rule of the strategically located nation that’s an international military and maritime hub.

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Apr 11 • 2:50 AM EDT • Politics • bloomberg.com
The Boundless Deep: Young Tennyson, Science, and the Crisis of Belief by Richard Holmes

Pantheon Review by Walter Cummins The image of Alfred Tennyson I’ve carried for decades goes back to the childhood card game of Authors that depicts him with a stately continence sharpened by a jutting black beard. He’s formidable, his aura superior. Holmes opens his biography of the youthful Tennyson by describing the similar formality of the imposing Tennyson statue at Trinty College Cambridge, sharing the honor with other Trinity greats, including Isaac Newton, Francis Bacon, and Thomas Babington Macaulay. Holmes doesn’t want to chip away at that statue but rather reveal its inner youthful core of the man—tall, handsome, and talented but unformed, emerging from a disturbed family of addicted or insane male siblings and four unusual sisters struggling under a violent alcoholic clergyman father. Alfred was certainly statuesque, but would he end up a block of unformed stone like his equally promising brothers? He was youngest of three equally regarded Tennyson brothers at Cambridge, all bright, handsome, and talented, in fact Alfred regarded by some as less promising than his elders who also wrote poetry. Yet Alfred wrote one of his major poems, “The Kraken,” at twenty, revealing both his talent, his interest in geological forces, and the haunting creature that embodied his anxieties. While Holmes focuses on Tennyson of the 1830s and 1840s, he can’t tell his story without exploring his involvement with the Victorian intellectual upheaval. Tennyson was fascinated by new scientific perspectives, following the latest findings as soon as books and articles were published. He was especially taken with Charles Lyell’s deep studies of geology and the discovery of fossils and a timeline of the planet’s development that did much to question fundamental religious assumptions. The impact of these discoveries is reflected in Tennyson’s poetry and led to the crisis in belief he shared with so many contemporaries. He was especially taken by the cycles of destruction and renewal that informed the struggles he confronted in In Memoriam, Maud, and Idylls of the King. Tennyson was only one of the eventual major figures at Cambridge at the same time, young men just beginning to realize their potential. Charles Darwin was at Christ College, although there is no evidence that he and Tennyson even met as students or later in life. Yet evolution became significant in Tennyson’s thinking and the issues of his poetry. One of Tennyson’s best and most important Cambridge friends was Edward FitzGerald, who became the translator of The Rubáiyát of Omar Khayyám and in their on and off relationship served as Tennyson’s harshest critic. FitzGerald was also a friend of the novelist William Makepeace Thackeray, the two of them partying in Paris as undergraduates. That connection led to a friendship between Thackeray and Tennyson. Others who came to play significant roles in Tennyson’s life were Thomas Carlyle, the Brownings, and the Pre-Raphaelites. Tennyson’s deepest friend at college was Arthur Hallam, who at twenty wrote a glowing review of Tennyson’s first poetry collection, travelled on European adventures with him, and fell in love with his sister Emily. Hallam was also regarded as one more very promising Cambridge student. His sudden death at twenty-two in Vienna from a stroke while travelling with his father devastated many friends, but perhaps Tennyson most of all. He did not write immediate poems of grief but took years to compile those collected in In Memoriam A.H.H., published in 1850, almost twenty years after Hallam’s death For all of Tennyson’s early poetic successes and successes, Holmes reveals him as an often troubled young man suffering periods of depression, fearing planetary upheaval, concerned about supporting himself, disappointed in romances, and worried that he would inherit the family’s mental illness tendencies. Yet despite his seeming withdrawals, he was always writing poetry that he kept private and would not let go, constantly revising. 1850 became a transformative year for Tennyson. He finally consented to publishing In Memoriam with a last-minute prologue that acknowledged God and perhaps convinced the religious Emily Sellwood to marry him after years of pursuit.. He opened up to Emily, revealing his struggles with fears of depression and “weird seizures.” The devastating event of that time was the stillborn death of his unnamed first son. It shook him, but Emily’s faith brought them closer and convinced him to believe in an afterlife. Two later sons survived. With the death of William Wordworth in April of 1950, Tennyson was named poet laureate at age forty-one, reluctantly accepting. It’s as if Tennyson’s life split in half in that year. He lived another forty years, now a recognized success, with the prestige of being an official poet writing patriotic verse, wealthy and revered, no longer the insecure young man seeking an outlet for his immense talent. He earned a place in the Authors deck, now dignified and in 1884 elevated to the peerage as Arthur, Lord Tennyson. Richard Holmes is the author of twenty previous books on the Romantics and Victorians, several of which received awards. The Boundless Deep was shortlisted for the 2025 Baillie Gifford Prize for Non-Fiction. He captures the complex vicissitudes of Tennyson’s youth, illustrated by frequent excerpts from the poetry, placing that life in the full context of the shattering discoveries that led to an upheaval of thought in the Victorian age.

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Apr 7 • 12:35 PM EDT • Science • calirb.com
A potential middleground in biomarker testing budget fight

A group of cancer survivors from around the state is set to gather outside Gov. Kathy Hochul’s Manhattan office on Tuesday.

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Apr 6 • 6:00 AM EDT • Health • politico.com
Why are people turning to at-home blood testing? Meet SiPhox Health

SiPhox Health makes at‑home blood testing easy with up to 60 biomarkers starting at $99 — no needles, no lab visits, just clear health insights.

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Apr 5 • 10:50 AM EDT • Health • usatoday.com
Scientists discover hidden gut signals that could detect cancer early

A new study reveals that gut bacteria and metabolites may hold the key to detecting serious digestive diseases earlier and more easily. Using AI, scientists found that biomarkers linked to one condition can often predict others, showing these diseases are more interconnected than previously thought. This cross-disease insight could lead to faster diagnoses without invasive procedures.

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Apr 4 • 8:00 AM EDT • Science • sciencedaily.com
Hims & Hers Health, Regeneron, Biogen, BioMarin Pharmaceutical, and Moderna Shares Are Falling, What You Need To Know

A number of stocks fell in the afternoon session after reports revealed that the US may impose up to 100% tariffs on imports of branded and patented drugs.

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Apr 2 • 8:08 PM EDT • Health • finance.yahoo.com
NIH awards $15.8 million to University of California for study of Latino brain health

A multisite study led by UC San Diego and UC Davis will examine changes in brain imaging, blood biomarkers and cognition over time in Latino and Hispanic people.

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Apr 2 • 6:19 PM EDT • Health • universityofcalifornia.edu
High school sports round up

Standout Claremont High School baseball team pitcher Brady Houlton delivers during the team’s 6-5 loss at Diamond Bar on Tuesday. With the loss the Wolfpack is now 2-1 in Palomares League play, 13-4 overall. Courier photo/Andrew Alonzo

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Apr 2 • 4:25 PM EDT • Sports • claremont-courier.com
Detroit Pistons final record prediction over last six games

Free Press sports writer Omari Sankofa II breaks down whether the Detroit Pistons can reach 60 wins in the 2025-26 season.

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Apr 2 • 5:08 AM EDT • Sports • sports.yahoo.com
Health Rounds: Researchers find biomarker that could lead to improved schizophrenia treatments

Researchers have identified a biomarker linked to ​schizophrenia that could lead to new treatments to tackle symptoms of the debilitating mental disorder not addressed ‌by current medicines.

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Mar 27 • 7:17 AM EDT • Health • reuters.com
Roseman University launches life science incubator to promote discoveries

Roseman University is launching a new life science incubator to support the growth of the biotechnology sector in Southern Nevada.

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Mar 26 • 2:21 PM EDT • Science • news3lv.com
Scientists Reflect on Experiences Meeting Patients

On the very best days, our researchers get to connect face to face with patients and families. Learn more about the meaning behind these moments.

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Mar 24 • 5:14 PM EDT • Science • biomarin.com
GrayMatters Health Announces Appointment of Five Expert Advisors

/PRNewswire/ -- GrayMatters Health (GMH), the pioneers of digital brain biomarkers for mental healthcare, today announced the addition of five expert advisors....

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Mar 24 • 9:00 AM EDT • Health • prnewswire.com
How Bans on Corporate Political Donations Influence Campaign Platforms

Julia Cagé, Caroline Le Pennec, and Elisa Mougin discuss their recent research on France’s 1995 ban on corporate contributions to political campaigns. The ban pushed candidates to de-emphasize local politics in favor of national issues and, in many cases, adopt more extreme rhetoric.

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Mar 24 • 6:00 AM EDT • Politics • promarket.org
Your Thymus and Your Healthspan

Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.

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Mar 22 • 2:18 PM EDT • Health • erictopol.substack.com
Pittsburgh Steelers salary cap update after free agency

The Pittsburgh Steelers were active in the early portion of free agency, with general manager Omar Khan making waves with a big-time trade for wide receiver Michael Pittman Jr. and several free agency additions.

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Mar 20 • 7:46 AM EDT • Sports • sports.yahoo.com
Illinois: Penn Entertainment's Hollywood Casino Aurora scheduled to open June 24

Penn Entertainment announced on Thursday that Hollywood Casino Aurora will open to the public on June 24, pending customary regulatory approvals. This will be the second new Penn property to... Read more »

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Mar 19 • 12:34 PM EDT • Entertainment • cdcgaming.com
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PENN Entertainment Sets June 24 as Grand Opening Date for New Hollywood Casino Aurora in Illinois

WYOMISSING, Penn. & AURORA, Ill., March 19, 2026--PENN Entertainment, Inc. ("PENN" or the "Company") (Nasdaq: PENN) announced today that it expects to open the new land-based Hollywood Casino Aurora to the public on Wednesday, June 24, pending customary regulatory approvals. This will be the second all-new PENN property to open in the Chicagoland region following the grand opening of the land-based Hollywood Casino Joliet in August 2025.

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Mar 19 • 10:00 AM EDT • Entertainment • finance.yahoo.com
Psychiatrists’ Use of Biomarkers Could Open a New Window Into Mental Health Diagnoses

The world’s largest professional psychiatry organization is preparing for the day when biological indicators can help diagnose and treat mental illness.

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Mar 17 • 5:00 AM EDT • Health • kffhealthnews.org
New cholesterol guidelines released by the American Heart Association

Also, for the first time, doctors are advised to test for two biomarkers in the blood that have been linked to increased risks of heart disease.

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Mar 13 • 3:11 PM EDT • Health • nbcnews.com
High-Signal Publisher
Ohio: Penn Entertainment to open hotel tower at Hollywood Casino Columbus June 12

Penn Entertainment announced on Thursday that it expects to open its new state-of-the-art hotel tower at Hollywood Casino Columbus on June 12, pending customary regulatory approvals. The 203-room hotel represents... Read more »

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Mar 12 • 10:58 AM EDT • Entertainment • cdcgaming.com
Samsung Galaxy S26 Ultra shows camera improvements compared to S25 Ultra, can't catch up to Apple iPhone 17 Pro

On paper, the Samsung Galaxy S26 Ultra has only received a few camera upgrades. An initial comparison by DxOMark now shows that Samsung was able to drastically improve the image quality in certain scenarios, but the camera system of the Galaxy S26 Ultra is not completely free of problems.

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Mar 8 • 2:32 PM EDT • Technology • notebookcheck.net
49ers go wide receiver in latest CBS Sports mock Draft

The 49ers will be busy with the wide receiver room in free agency, might they address it with Indiana’s Omar Cooper Jr?

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Mar 8 • 9:13 AM EDT • Sports • sports.yahoo.com
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Difficult people in your life might make you age faster, study suggests

New research suggests that difficult people, aka hasslers, contribute to chronic stress and elevate epigenetic biomarkers associated with aging.

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Mar 8 • 6:00 AM EDT • Health • washingtonpost.com
WATCH: Walz, Ellison, Omar refuse to answer when pressed on fraud after contentious fraud hearing

Minnesota Gov. Tim Walz and AG Keith Ellison stay silent after heated House hearing on alleged $10 billion fraud scandal that rocked the state government.

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Mar 6 • 10:49 AM EST • Politics • foxnews.com
TITAN Group Completes the Acquisition of Traçim Cement in the Greater Istanbul Market

Regulatory News: Titan SA (Euronext Brussels, ATHEX and Euronext Paris, TITC) announces that, following all customary approvals, it has completed the acquisi...

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Mar 5 • 4:33 AM EST • Business • businesswire.com
Neogen Announces Sale of Genomics Business to Zoetis

LANSING, Mich., March 02, 2026--Neogen Corporation (NASDAQ: NEOG), an innovative leader in food safety solutions, announced today it has entered into a definitive agreement to sell its global genomics business to Zoetis Inc. ("Zoetis"), the world’s leading animal health company, for $160 million, subject to customary closing adjustments. The planned divestiture, which had been previously announced, was part of the company’s portfolio review strategy to simplify the business and focus on core str

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Mar 2 • 7:00 AM EST • Business • finance.yahoo.com
Omar, Squad lash out at Trump in response to Iran strike: 'Illegal regime change war'

President Trump's decision to attack Iran was quickly slammed by progressive members of the House including Reps. Ilhan Omar, Rashida Tlaib, and Greg Casar.

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Feb 28 • 11:09 AM EST • Politics • foxnews.com
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Javier Palomarez, USHBC President, Warns State of the Union Is Disconnected from Small Business Reality

WASHINGTON, Feb. 25, 2026 (GLOBE NEWSWIRE) -- Last night’s State of the Union address focused heavily on economic momentum, stock market performance, energy policy, immigration enforcement, and tariffs. While President Trump emphasized record market highs and economic resilience, recent polling among Hispanic business owners suggests a widening gap between macroeconomic indicators and kitchen-table reality. According to the United States Hispanic Business Council (USHBC)’s most recent survey of

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Feb 25 • 12:52 PM EST • Business • finance.yahoo.com
Rep. Omar: I had to remind him that his administration was responsible for killing two of my constituents
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Feb 25 • 11:34 AM EST • Politics • cnn.com
😐 Neutral (0%)
‘You have killed Americans’: Ilhan Omar tries to shout down Trump’s immigration attacks

For the first hour of President Donald Trump’s State of the Union address Tuesday, Democrats in the House chamber largely stuck to their plan: Sit in stony, defiant silence.

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Feb 25 • 12:12 AM EST • Politics • cnn.com
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Downtown Santa Cruz partially closed off due to mental health incident

Police blocked off a section of downtown Santa Cruz, Saturday afternoon, after witnesses reported seeing objects being thrown from a window at the Palomar Inn.

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Feb 22 • 12:41 AM EST • Health • ksbw.com
Omar calls GOP probe into husband’s $30M business surge a ‘political stunt’ as records deadline passes

Rep. Ilhan Omar called GOP investigation into her finances a "political stunt" as the deadline to provide business records about husband's companies blew by on Thursday.

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Feb 20 • 2:08 PM EST • Business • foxnews.com
Omar calls GOP probe into husband’s $30M business surge a ‘political stunt’ as records deadline passes

Rep. Ilhan Omar called GOP investigation into her finances a "political stunt" as the deadline to provide business records about husband's companies blew by on Thursday.

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Feb 20 • 2:08 PM EST • Politics • foxnews.com
Oral bacteria may signal metabolic health and even contribute to obesity

It turns out your mouth may know more about your metabolism than your bathroom scale. New research shows that people with obesity host a distinct oral microbiome compared to individuals at a healthy weight. Rather than zeroing in on the gut microbiome, the study turns our attention to the mouth as a potential biological signal of metabolic health. It’s a shift that could challenge long-held assumptions about where obesity-related biomarkers can be measured.

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Feb 14 • 7:03 PM EST • Health • newatlas.com
Mattel to Acquire Full Ownership of Mattel163 Mobile Games Studio, Strengthening its Digital Games Business

EL SEGUNDO, Calif., February 10, 2026--Mattel, Inc. (Nasdaq: MAT), a leading global play and family entertainment company and owner of one of the most iconic brand portfolios in the world, today announced an agreement with its joint venture partner, NetEase, a leading internet and game services provider, to acquire full ownership of the Mattel163 mobile games studio. The transaction is expected to be completed by the end of Q1, subject to customary closing conditions.

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Feb 10 • 4:10 PM EST • Business • finance.yahoo.com
Are Steelers Done with Trenches Rebuild?

The Pittsburgh Steelers spent the first three draft classes under general manager Omar Khan and assistant general manager Andy Weidl […] This article originally appeared on Steelers Now: Are Steelers Done with Trenches Rebuild? | Locked On Steelers

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Feb 10 • 10:00 AM EST • Sports • sports.yahoo.com
Dem lawmaker slams Ilhan Omar probe as 'playing politics'

Fox News chief congressional correspondent Chad Pergram has the latest on the probe into Democratic Rep. Ilhan Omar's personal wealth on 'The Faulkner Focus.'

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Feb 9 • 2:22 PM EST • Politics • foxnews.com
😐 Neutral (14%)
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House Oversight launches probe into Rep. Ilhan Omar’s finances, husband’s business dealings

Fox News chief congressional correspondent Chad Pergram reports as House Oversight launches an investigation into Rep. Ilhan Omar over questions about her finances and her husband’s income.

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Feb 9 • 12:06 PM EST • Business • foxbusiness.com
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Linus Torvalds Confirms The Next Kernel Is Linux 7.0

Following Linus Torvalds releasing Linux 6.19 stable, Linus Torvalds is now out with his customary release announcement

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Feb 8 • 4:36 PM EST • Technology • phoronix.com
Oversight chair Comer requests wide range of business documents from Ilhan Omar’s husband

The sharp valuation of two companies owned in part by the lawmaker’s husband, Tim Mynett, has led Trump to suggest Omar has committed fraud.

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Feb 6 • 3:15 PM EST • Business • minnpost.com
James Comer demands business records from Rep. Ilhan Omar's husband
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Feb 6 • 10:56 AM EST • Business • nypost.com
Trump claims Minnesota fraud exceeds $19B, faults Biden administration

President Donald Trump renews attacks on Rep. Ilhan Omar and Gov. Tim Walz over the Minnesota fraud scandal linked to the Somali community.

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Jan 31 • 9:46 AM EST • Politics • foxnews.com
Inner plexiform layer substrata: Possible biomarker of retinal health | Ophthalmology Times - Clinical Insights for Eye Specialists

Ophthalmology Times connects eye care professionals with surgery, imaging, gene therapy, & diagnostic advances to enhance clinical and patient care.

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Jan 31 • 6:12 AM EST • Health • ophthalmologytimes.com
School of Business dean to step down, return to faculty in May - News

Dr. Kevin O’Mara announced this week he will step down as dean of the Lundy-Fetterman School of Business at Campbell… More on this post

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Jan 30 • 11:44 AM EST • Business • news.campbell.edu
The attack on Ilhan Omar and Trump’s destructive politics of violence

The president's rhetoric portends worse to come.

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Jan 29 • 3:58 PM EST • Politics • motherjones.com
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After assault on Ilhan Omar, Trump responds with another blame-the-victim conspiracy theory

President Donald Trump did it after the 2021 attack on the US Capitol. He did it after the 2022 attack on the husband of then-House Speaker Nancy Pelosi. He did it after the murder last month of filmmaker and Democratic activist Rob Reiner. And he did it again on Tuesday after an attack on another Democrat, Rep. Ilhan Omar of Minnesota.

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Jan 29 • 8:42 AM EST • Politics • cnn.com
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Rep. Ilhan Omar points finger at Trump's 'hateful rhetoric' after town hall attack

The man accused of carrying out the assault has social media accounts that include multiple photos in support of Trump and criticizing Democrats. The FBI is investigating.

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Jan 28 • 11:36 PM EST • Politics • nbcnews.com
High-Signal Publisher
Trump has 'dementia', is 'obsessed,' Ilhan Omar says following attack

The Minnesota Democrat’s comments come in the wake of an attack on her Jan. 27 where a man sprayed her with an unknown substance.

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Jan 28 • 8:49 PM EST • Politics • usatoday.com
America at a Boiling Point: From ICE Protests to an Attack on Rep. Omar

An attack at a town hall in Minneapolis, amid a surge in threats against lawmakers, was the latest sign of the fraying of the nation’s political fabric.

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Jan 28 • 7:47 PM EST • Politics • nytimes.com
Attack on Ilhan Omar Follows Years of Trump’s Targeting Her

President Trump has spent years demonizing and dehumanizing the Somali-born Democrat from Minnesota, fueling escalating threats against her.

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Jan 28 • 5:33 PM EST • Politics • nytimes.com
What we're learning about the man arrested in the attack on Rep. Ilhan Omar

Anthony Kazmierczak hadn't been formally charged or scheduled for an initial court appearance as of Wednesday morning.

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Jan 28 • 3:32 PM EST • Politics • pbs.org
Social Sciences in the News: Political Science Professor Omar Wasow

Political Science Professor Omar Wasow authored an op-ed in The New York Times titled "We’re Seeing the Weakness of a Strong State." I study the political consequences of protest and state violence.

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Jan 28 • 12:38 PM EST • Science • ls.berkeley.edu
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‘I don’t let bullies win’ Ilhan Omar says after attack, as Trump says he will ‘de-escalate’ in Minneapolis

President had mocked congresswoman hours before she was sprayed with unknown substance during a town hall event

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Jan 28 • 7:07 AM EST • Politics • theguardian.com
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After town hall attack, Ilhan Omar condemns ‘terrorizing’ immigration push and criticism from GOP

Minnesota Rep. Ilhan Omar ignored staffers’ pleas to end a town hall early and get a medical check Tuesday after a man rushed the podium and sprayed a substance at the Democratic congresswoman.

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Jan 27 • 9:55 PM EST • Politics • cnn.com
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Minnesota Representative Ilhan Omar attacked during town hall meeting

Ilhan Omar was sprayed with an unknown substance during the attack by man who was tackled to the ground.

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Jan 27 • 8:29 PM EST • Politics • aljazeera.com
Man douses Ilhan Omar with unknown substance at town hall in Minneapolis

The congresswoman pledged to keep speaking. People close to her said the substance smelled "terrible" and called on her to "go get checked."

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Jan 27 • 8:27 PM EST • Politics • usatoday.com
☹️ Negative (-34%)
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100%
Under Biden Administration, Justice Dept. Began Examining Ilhan Omar’s Finances

The inquiry, initiated by the U.S. attorney’s office in Washington, appears to have stalled for lack of evidence.

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Jan 26 • 4:15 PM EST • Politics • nytimes.com
Barzan exec talks new business plan, unveils agreements and new platforms

“We're focused much more on what is made in Qatar, things that we've developed and produced here locally," Barzan Chief Commercial Officer Omar Al Qadi told Breaking Defense.

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Jan 22 • 2:36 PM EST • Business • breakingdefense.com
The New Gold Rush in Brain Science

Fueled by advances in biomarkers, brain mapping, and AI, investment in neuro and CNS innovation shows no signs of slowing, even amid costly setbacks. BioSpace spoke to investors at JPM26 to get their take on recent bets in new therapies and neurotech.

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Jan 22 • 3:00 AM EST • Science • biospace.com
EXCLUSIVE: Justice Department leadership presses FBI to investigate campaign contributions to Minnesota officials

Top Justice Department officials pushed the FBI to investigate political campaigns in Minnesota over whether they illegally benefited from fraud in public service organizations, according to two people familiar with the internal discussions.

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Jan 20 • 3:50 PM EST • Politics • cnn.com
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Global Citizen Appoints Industry Leaders in Entertainment, Business, Technology and Sports to Board of Directors

NEW YORK, January 19, 2026--Global Board Welcomes John Legend, Avie Glazer, Mariam Almheiri, Omar Al-joulani, and Ankur Jain to Board of Directors

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Jan 19 • 8:00 AM EST • Entertainment • finance.yahoo.com
Trump asserts Ilhan Omar should be jailed or booted to Somalia

President Donald Trump declared in a Truth Social post that Democratic Rep. Ilhan Omar of Minnesota should be placed in jail or sent to Somalia.

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Jan 19 • 7:19 AM EST • Politics • foxnews.com
Start the New Year Strong: UCTV’s “Best of” Health and Science Programs for 2026

Looking for inspiration to start the year feeling energized and informed? UCTV’s free, on-demand programs have reached millions of people worldwide, offering real science and practical takeaways. Learn about the “best of” viewer favorites for 2026—and transform your year.

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Jan 14 • 7:00 PM EST • Science • today.ucsd.edu
AppleInsider.com

Withings is doing more than ever with its latest smart scale, the Body Scan 2. AT CES, the brand is calling it a "longevity station" with more than 60 biomarkers and Apple Health integration.

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Jan 4 • 8:00 PM EST • Health • appleinsider.com
Withings' updated Body Scan scale tracks 60 different biomarkers

Body Scan 2 will keep a better eye on your heart health.

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Jan 4 • 8:00 PM EST • Technology • engadget.com
Ilhan Omar disclosures show husband’s companies surged in value as Minnesota reels from $9B fraud

Disclosures show that companies owned by the husband of Rep. Ilhan Omar surged in value, from under $1,000 to up to $25 million, as investigations into Minnesota fraud continue.

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Dec 29, 2025 • 10:54 AM EST • Politics • foxnews.com
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Impact of Microplastic Exposure on Human Health: A Systematic Review of Mechanisms, Biomarkers, and Clinical Outcomes

Microplastics (≤5 mm) are increasingly recognized as pervasive environmental pollutants with potential implications for human health. Human exposure occurs primarily through ingestion and inhala...

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Dec 27, 2025 • 7:00 PM EST • Health • cureus.com
Mexico's movers and shakers: 7 political figures you need to know

Mexico's top political figures include Security Minister Omar García Harfuch, business leaders like Altagracia Gómez, ambassador Ronald Johnson and more.

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Dec 26, 2025 • 7:13 PM EST • Politics • mexiconewsdaily.com
Democratic Rep. Crockett says Vance used ‘racist tropes’ in comments about her

Two Black Democrats, Rep. Jasmine Crockett and Minnesota state Sen. Omar Fateh, criticized comments the vice president made about them during his weekend speech at a Turning Point gathering.

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Dec 22, 2025 • 3:13 PM EST • Politics • washingtonpost.com
Trump alleges Ilhan Omar ‘hates Jewish people’ at Hanukkah event

Trump has repeatedly targeted Rep. Ilhan Omar, who is Muslim, since his first term as president.

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Dec 17, 2025 • 12:14 PM EST • Politics • usatoday.com
Congresswoman Ilhan Omar says ICE agents pulled over her son

Somali-born Minnesota representative says her son was let go once he produced his ID

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Dec 15, 2025 • 7:50 AM EST • Politics • theguardian.com
😐 Neutral (14%)
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60%
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Southwick business reaches agreement over loan fraud

As part of the settlement, Comark admitted to receiving a PPP loan in January 2021, meant to be used as financial assistance during the covid pandemic.

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Dec 12, 2025 • 9:53 PM EST • Business • westernmassnews.com
Fox News Politics Newsletter: Omar accused of opening door to massive Minneapolis fraud

Welcome to the Fox News Politics newsletter, with the latest updates on the Trump administration, Capitol Hill and more Fox News politics content.

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Dec 12, 2025 • 3:16 PM EST • Politics • foxnews.com
How Political Alignment Between Cities and Governors Shapes Municipal Borrowing Costs

In new research, Ramona Dagostino and Anya Nakhmurina discuss how political misalignment between state governors and city leadership can affect how cities access financing, particularly in municipal bond pricing and crisis prevention investment.

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Dec 12, 2025 • 6:00 AM EST • Politics • promarket.org
Week 15 Fantasy Football RB preview: Starts/sits, DFS, more

Heath Cummings gets you set with RBs to start, sit, stream and play in DFS lineups in Week 15

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Dec 9, 2025 • 3:35 PM EST • Sports • cbssports.com
Chargers vs. Eagles prediction, odds: 'Monday Night Football' picks today from 10,000 simulations

SportsLine's model simulated Philadelphia vs. Los Angeles 10,000 times and revealed its 'MNF' best bets

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Dec 8, 2025 • 6:43 PM EST • Sports • cbssports.com
Trump rails against Somali migrants: ‘I don’t want them in our country’

The president blasted Minnesota’s Somali community as “garbage” in a rant also attacking Gov. Tim Walz and Rep. Ilhan Omar.

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Dec 2, 2025 • 5:10 PM EST • Politics • washingtonpost.com