SCROLL NEWS / DISCOVERY
Search headlines
Find the stories shaping the conversation.
Results for " barcelona " 471 found 🔀 AI-powered Shuffle
Barcelona vs Feyenoord – Match preview and team news
Barcelona will aim to register their fifth straight victory this season when they kick off their UEFA Champions League campaign on Wednesday against Feyenoord at the Camp Nou.Barcelona vs Feyenoord �...
Barcelona vs Feyenoord – Predicted lineup and team news
Barcelona will be chasing a fifth consecutive win of the season as they begin their UEFA Champions League journey on Wednesday, hosting Feyenoord at the Camp Nou.FC Barcelona arrive in the competition...
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
Message for Mbappé? Lamine Yamal: title winners all press
Lamine Yamal has spoken at a press conference ahead of Barcelona-Feyenoord. The Champions League as a challenge"There is no greater motivation for me than winning the Champions League, it’s the most...
Barcelona forward’s adaptation progressing slower than his fellow summer arrival
FC Barcelona summer signing Anthony Gordon has made an excellent start to life at the club.Signed for €70 million plus add-ons from Newcastle United, the England forward has hit the ground running i...
How will Barcelona line up against Feyenoord?
Hansi Flick’s possible XI for Wednesday’s clash
Hansi Flick sent strong Jose Mourinho message by Barcelona
Don’t get drawn into the circus.
How Gabriel Jesus turned rejection to acceptance from Barcelona
Gabriel Jesus completed his move to Barcelona in the final days of the last transfer window, but it was a move that had been in the making for a long time.The Brazilian was one of the players struggli...
DeAPlaneta on its New and Fast-Growing IPs
Based in Barcelona, Spain, DeAPlaneta Entertainment hints at what is to come from their current and new IPs.
Barcelona youngster could be handed minutes vs Feyenoord
An up-and-coming member of the attacking ranks at La Liga giants Barcelona could yet be afforded minutes off the bench in the club’s European season opener.This comes amid confirmation that Jesse Bi...
Barcelona forecast €1.195 billion in revenue for 2026/27
FC Barcelona have now announced their financial figures ahead of the upcoming General Assembly, providing full access to the club members now about the economic situation.The accounts for the 2025/26 ...
Record revenue! Barça tops €1 billion 💰
FC Barcelona has already made public the figures for the 2025-26 season and the forecasts for 2026-27. Members will vote to approve this balance sheet at the Ordinary General Assembly next Saturday, S...
🥐 Barça romp, Diomande case... 5️⃣ stories to start Monday
FC Barcelona strengthened their grip on top spot after thrashing Valencia at Mestalla, while tension has taken over the Valencian club’s surroundings and Madrid are gearing up for their European deb...
🗞️ Monday’s front pages, Barça masterclass, crisis at Valencia...
This Monday’s sports press places FC Barcelona’s emphatic thrashing at Mestalla (0-5) at the center of attention, a commanding win that cements the Blaugrana as the sole leaders of LaLiga. In cont...
Bacteria found in classroom dust may affect children’s respiratory health
Common bacteria found in classroom dust are associated with reduced lung function in children according to research presented at the European Respiratory Society (ERS) Congress in Barcelona, Spain.
Yamal hits double as perfect Barca thrash Valencia
Lamine Yamal struck twice for Barcelona as they demolished Valencia 5-0 on Sunday to maintain their 100 percent start in La Liga.The reigning champions moved three points clear at the top of La Liga, after Jose Mourinho's Real Madrid lost 1-0 at Real Betis on Friday.
Barcelona star forced off during Valencia clash
La Liga giants Barcelona have on Sunday been dealt a potential blow on the personnel front. This comes owing to developments in the Blaugrana’s latest outing on the domestic front.Hansi Flick’s tr...
Confirmed: Barcelona starting line up to face Valencia
Barcelona are looking for their fourth consecutive victory this season as they take on Valencia at the Mestalla this afternoon.Ahead of this clash, Barcelona have unveiled their starting eleven that w...
Away games offer Julian Alvarez a route back at Atletico
Julian Alvarez is going nowhere, at least until January. But the Argentina forward’s public preference for a move to Barcelona over the summer has left Diego Simeone with a delicate problem that no ...
Valencia vs Barcelona, La Liga: TV & Streaming, Live Thread
Join us for another Barcelona La Liga adventure!
Barcelona XI vs Valencia – Predicted lineup and team news
Barcelona are set to face Valencia in their upcoming La Liga fixture on Sunday, aiming to extend their impressive winning streak at the start of the new campaign.Hansi Flick’s Barcelona have made a ...
Barcelona squad named for Valencia
Hansi Flick has called up 24 players for Sunday’s clash
Valencia vs Barcelona, La Liga: Preview
A chance for an early statement in the title race
Barcelona star to be left out of squad vs Valencia
One member of the squad called upon by La Liga giants Barcelona for their upcoming meeting with Valencia will be omitted from the club’s official matchday list. This comes owing to an overbooking in...
Athletic Bilbao crush Simeone's flat Atletico
Athletic Bilbao thumped Atletico Madrid 3-0 in La Liga on a miserable Saturday afternoon for Diego Simeone's side.On Sunday, La Liga leaders Barcelona visit Valencia looking to move clear of Real Madrid, who lost 1-0 at Real Betis on Friday, among other fixtures. rbs/pb/dmc
Barcelona must decide what to do with additional €60m
Funds are available ahead of the January transfer window.
Athletic Bilbao crush Simeone's flat Atletico
Athletic Bilbao thumped Atletico Madrid 3-0 in La Liga on a miserable Saturday afternoon for Diego Simeone's side.On Sunday La Liga leaders Barcelona visit Valencia looking to move clear of Real Madrid, who lost 1-0 at Real Betis on Friday, among other fixtures. rbs/pb
FC Twente chief responds to Barcelona interest in Ruud Nijstad
The teenager has plenty of admirers.
Flick hoping Barca's Yamal can face Valencia after knock
Barcelona coach Hansi Flick is hoping teenage star Lamine Yamal is fit to face Valencia in La Liga on Sunday after taking a knock."Lamine is a player who likes to play football."
Barcelona midfielder eyeing special milestone against Valencia
Rodri’s inclusion into Hansi Flick’s plans has been measured and cautious, for the manager is aware of the player’s fitness struggles and recent injury history.When fit, there is no doubt that t...
Barcelona train without Lamine Yamal ahead of Valencia clash
The forward has emerged as a doubt for the match.
Barcelona’s new captain hierarchy confirmed with one surprise addition
Barcelona have finalised their captaincy structure for the 2026/27 season, with Lamine Yamal making a major leap into the leadership group despite being only 19.According to Mundo Deportivo, Hansi Fli...
How will Barcelona line up against Valencia?
Hansi Flick’s possible XI for Sunday’s clash
Kerolin Nicoli move signals Barcelona’s new transfer ambition
Barcelona have signed Brazilian forward Kerolin Nicoli, 26, from Manchester City for a reported £1.25m, according to Sky Sports. The fee is the highest ever received for a Women’s Super League play...
Arsenal to face Barca & Lyon in Women's Champions League
Arsenal will face holders Barcelona and record winners Lyon in the Women's Champions League, while Chelsea will travel to Lyon and Man City will take on Bayern Munich.
Opponent watch: Valencia’s injury crisis deepens ahead of Barcelona visit
FC Barcelona will lock horns with Valencia this Sunday in a Matchday 4 fixture of the 2026/27 La Liga season.The Blaugrana will visit Mestalla having already won each of their three games this season ...
Why Julián Álvarez’s Barcelona Dream Still Faces Atlético’s Veto
Julián Álvarez ended the summer window still on Atlético Madrid’s books, but that outcome has settled almost nothing. Barcelona spent the entire market chasing the Argentine, Atlético publicly r...
🗞️ Champions buzz in Seville, Barça shielded... Friday's front pages
This Friday, September 4, the sports press comes packed with major football headlines: Carlo Ancelotti’s star visit to Real Madrid’s training camp before facing Betis, Barcelona’s moves to secur...
Barcelona’s financial fair play situation explained after huge summer spending
Barcelona have emerged from one of their busiest transfer windows with almost the same Financial Fair Play margin they had when the summer began.According to SPORT, despite spending €182.5 million o...
Inter Milan star responds to Barcelona transfer links
Inter Milan striker and captain Lautaro Martínez has this week spoken publicly for the first time on the recent transfer speculation linking him with a move to La Liga champions Barcelona.Frontman La...
Deco Leaves Barcelona Without Late Centre-Back or Striker Deal
Barcelona sporting director Deco has confirmed the club will make no further signings before the summer window shuts, ending speculation over a late defensive addition or another forward following the...
Gabriel Jesus: Arsenal forward completes Barcelona transfer in £8.6m deal on Deadline Day
Gabriel Jesus leaves Arsenal having scored 32 goals in 123 appearances for Arsenal since his £45m move from Manchester City in 2022; Jesus move is not expected to impact Barcelonas desire to sign Julian Alvarez
Analysis: Encouraging signs for new boss Jaissle
Newcastle fans may well have found themselves in the opposite position to Spurs supporters before the campaign had started - fearful of what was coming. Tonali was one of three key departures from St James' Park, along with captain Bruno Guimaraes, who went to Arsenal for £85m this month, and England winger Anthony Gordon after his £69m move to Barcelona. Manager Eddie Howe left on 31 July after nearly five successful years, which included guiding the Magpies to their first domestic trophy in 70 years with victory in the 2025 Carabao Cup.
The key points from Joan Laporta’s crucial meeting with Barcelona’s sports committee
Barcelona are heading into the final week of the transfer window with a clear message emerging from the club’s sporting leadership: Julian Alvarez remains the target, and there is little interest in...
Julian Alvarez transfer latest: Atletico standing firm on Barcelona as Arsenal become only get out for Argentine striker
Julian Alvarez is holding out for a move to Barcelona, but Atletico Madrid are standing firm on the refusal to sell to their LaLiga rivals; Atletico football expert Ruben Uría believes the only way out for Alvarez is to join Premier League champions Arsenal
🥐 An unstoppable Barça, Julián, Vinicius... 5️⃣ stories shaping Monday
Tension at the Metropolitano after the boos aimed at Julián Álvarez headline a matchday in which FC Barcelona showed overwhelming dominance against Elche, Mourinho stepped in amid the 'Vinicius case...
Deco Travels to Madrid as Barcelona Keep Álvarez Pursuit Alive
Barcelona have not walked away from Julián Álvarez, but Atlético Madrid remain adamant that they will not sell. That impasse was at the centre of Deco’s discreet trip to Madrid, where the Barcelo...
Barcelona Set €20m Hurdle as Balde Transfer Interest Grows
Benfica and Aston Villa have both made initial enquiries to sign Barcelona left-back Alejandro Balde, according to Diario SPORT. The 22-year-old has reportedly instructed his agent, Jorge Mendes, to f...
Barcelona face striker dilemma - could they cope without one?
Barcelona are heading into the new La Liga season without an established striker, with Hansi Flick yet to replace Robert Lewandowski and Ferran Torres.
Man Utd transfer news: Barcelona midfielder Gavi rejects chance to join Old Trafford
Latest transfer news and headlines as Crystal Palace star Adam Wharton emerges as a Man City midfield target; Saudi side Al Hilal have submitted a £38.5m bid for Aston Villa striker Ollie Watkins; Harry Kane is ready to snub Saudi millions and commit his future to Bayern Munich
Barcelona want Julián Álvarez to make his Atlético stance public
Barcelona are expecting Julián Álvarez to publicly declare his desire to leave Atlético Madrid now that the World Cup has concluded, according to SPORT. The report claims the Blaugrana have set Jul...
Barcelona’s friendly against FC Basel is nearly impossible to watch
This is disappointing
Barcelona Add Sporting CP Striker to Álvarez Shortlist
Barcelona are exploring Sporting CP forward Luis Suárez as a potential alternative to Julián Álvarez, with Atlético Madrid continuing to resist a move for the Argentine international. Fabrizio Rom...
Hansi Flick identifies five alternatives to solve Barcelona’s striker absence
Barcelona find themselves in an unusual position heading into the new season.Following the departures of Robert Lewandowski and Ferran Torres, Hansi Flick currently has no natural senior centre-forwar...
FC Barcelona Has Another Rodri Offer Rejected By Manchester City
FC Barcelona has had another bid rejected by Manchester City for its World Cup winner and star midfielder Rodri.
Rodri Chooses Barcelona as €60m City Deal Edges Closer
Barcelona are expected to pay around €60 million to Manchester City to sign Rodri, according to Diario AS, as reported by Barca Universal. The report also states that the Spain international is set ...
Barcelona defender’s agent visits club facilities amid growing Arsenal interest
With the transfer window entering its final stages Jules Kounde’s future at FC Barcelona is starting to become uncertain. Now, According to Jijantes (h/t SPORT), Jonathan Kebe, the French defender��...
Barcelona-linked Premier League defender chooses to join Atletico Madrid
Cristian Romero has made a decision on his future The Argentine centre-back had interest from several clubs, most notably Atletico Madrid, Barcelona, Inter Milan and Arsenal, but according to reports ...
FC Barcelona Coach Flick Makes Season Promise And Confirms Exits
Barcelona head coach Hansi Flick made a promise to the team's fans and also confirmed the exits of a couple of players.
Barcelona vs Nottingham Forest, Preseason: Live Thread
Join us for Barça’s next preseason adventure!
Liverpool Signs FC Barcelona Defender Ronald Araujo In Shock Transfer
Liverpool has signed FC Barcelona defender Ronald Araujo according to a number of leading transfer market experts.
🥐 Transfer market erupts, 5️⃣ stories shaping Friday
The transfer market explodes this August 7 with historic moves in the capital and Barcelona. Amid record-breaking figures in Chamartín, unexpected twists in negotiations involving the biggest stars, ...
I flew business class on a budget airline—and it wasn't what I expected
A firsthand look at JetBlue's new Boston-to-Barcelona flight, from lie-flat seats to food, service, and what's actually worth it.
Barcelona’s Joao Pedro Transfer Pursuit Sees Key Development
FC Barcelona's pursuit of Joao Pedro has seen a key development in the past few days, as per reports in the UK and Catalonia.
FC Barcelona Star Torres Receives PSG Warning, Reports SPORT
FC Barcelona star and World Cup winner Ferran Torres has been sent a warning by a club that wants him in Champions League holder Paris Saint-Germain.
Barcelona renew interest in Hoffenheim attacker Fisnik Asllani
Kicker confirms a report originating in Catalan sports newspaper Sport regarding FC Barcelona’s interest in Hoffenheim attacker Fisnik Asllani. Apparently, the Blaugrana are once again considering T...
Deadline approaches for Barcelona’s offer for Julian Alvarez
FC Barcelona’s pursuit of Julian Alvarez has reached a crucial stage after club president Joan Laporta confirmed that the offer made for the Atletico Madrid striker would not remain valid indefinite...
Barcelona Signs Forward Karim Adeyemi From Borussia Dortmund Until 2031
Spanish champion Barcelona has signed forward Karim Adeyemi from Borussia Dortmund on a five-year contract.
Barcelona postpone official announcement of Karim Adeyemi transfer to Thursday
According to SPORT, Barcelona have postponed the official announcement of their second signing of the summer, with Karim Adeyemi set to be confirmed and unveiled on Thursday, July 23, after several da...
Joan Laporta uses US World Cup trip to strengthen Barcelona’s business and football ties
Joan Laporta’s trip to the United States was about much more than watching FC Barcelona’s players compete at the World Cup.The Barça president used five busy days in Dallas and New York to combin...
Potential announcement date revealed for new Barcelona signing
Barcelona had wrapped up the deal to sign Karim Adeyemi earlier in the month, with the Catalan swooping out of nowhere to acquire the services of the explosive winger.Borussia Dortmund have already co...
Arsenal planning short-term move for free agent John Stones following William Saliba's World Cup injury
Plus: Tottenhams Djed Spence is keen on a move to Inter Milan; Chelseas stance on Joao Pedro has been revealed amid interest from Barcelona; Fulham boss Alvaro Arbeloa plans a raid on former club Real Madrid
Barcelona facing transfer dilemma with Ferran Torres
The club have a big decision to make.
47 revelatory hours with Assassin’s Creed Black Flag Resynced
To review this month’s supposed remake of 2013’s Assassin’s Creed IV: Black Flag, I must first correct the record. Assassin’s Creed Black Flag Resynced isn’t a game about pirates (and assassins) in the 18th century Caribbean. Sure, sure, that’s what the trailers would have you believe. They’ve go their clips of Edward Kenway swinging his swords and steering his pirate ship into cannon-blasting combat against British frigates. Is Resynced truly a pirate game? Of the 47 hours I spent playing Resynced over the past few weeks, I will admit I spent maybe 44 (?) of them collecting plunder with Blackbeard, drinking rum with Anne Bonny and debating the pros and cons of the lawless pirate-run settlement Nassau with Benjamin Hornigold. I may in fact have spent dozens of hours sailing to remote islands, reading treasure maps, opening messages left in bottles, sinking the odd Man o’ War with a well-timed broadside, collecting sea shanties for my crew, befriending a pet monkey, and hunting whales. I am nevertheless neither so Gullible nor so Narrow-Minded as to call the magnificent Resynced a “pirate remake.” Oh no. Forget any reviews of Assassin’s Creed Black Flag Resynced you may have read. Forget what you yourself may have played, if you’ve spent any time with the game since its launch. What Assassin’s Creed Black Flag Resynced is really about I’m here to give you the scoop (spoilers for Resynced’s Animus menu lore, which many players are probably not going to see): Assassin’s Creed Black Flag Resynced, the new game whose development was led by Ubisoft Singapore, is set in the year 2096. It’s about a societal split, about revolution, about an old Assassin’s Creed adventure repurposed in the series’ distant future as propaganda or samizdat. It’s about the overheated future of 2096, essentially conquered by the series’ well-established nefarious Templar-run company Abstergo. (In this future, Abstergo is, among other things, remaking a 2013 pirate movie called Devils of the Caribbean, but this time in VR. The VR version will be backed by a marketing plan that involves AI influencers, a 10,000-avatar “metaverse premiere event” and that manufacturing of memes aimed at “50 million VR nodes.” See what I mean about Abstergo being evil?) Resynced is about a late 21st-century population mollified by the widespread use of Abstergo’s Animus devices which let people experience the lives of historical figures culled from “genetic memories.” It’s about an insurgent faction of Assassins. And it’s about a plan to wake the population into revolutionary fervor by showing them the memories of 18th century pirate Edward Kenway, who—as depicted in the original Black Flag and again in Resynced—gradually comes to an understanding about the Assassins of his day and their centuries old fight for freedom. Resynced is also about an AI developed within the late 21st-century Animus, called Ego. It has found a way to alter genetic memories, to create and show Animus users false ones. The game is about Ego’s efforts to tell the people experiencing Edward Kenway’s memories that Kenway was wrong, that fighting against order is folly, that we should crave a world where “compliance is rewarded with power.” Who are we in this game? We’re an unnamed Animus user in 2096 who experiences Kenway’s journey virtually. At four moments during Kenway’s exploits in the Caribbean our virtual jaunt can be interrupted for 10-15 minutes, as we explore Animus “rifts” where Ego explicitly tries to tell us how wrong Kenway was. None of this is what 2013’s Assassin’s Creed IV: Black Flag was about, of course. That was a different game, even if you also spent dozens of hours pirating as Kenway in that game, across missions and a map that’s been faithfully reintroduced and rebuilt for Resynced. The 2013 Black Flag was about you playing as an unnamed researcher newly hired in 2013 by Abstergo Entertainment, the video game development wing of the Templars’ evil-corp. In that game, you were assigned to use the Animus to dive into the genetic memories of Desmond Miles, a man who died in Assassin’s Creed III and who was descended from a long line of Assassins (and at least one Templar) whose adventures were featured across the prior AC games. In 2013’s Black Flag, your mission was to plumb the Edward Kenway experience for material that Abstergo could use in productions such as the motion picture Devils of the Caribbean, though the Templars had some ulterior motives for the assignment. Resynced is therefore not a remake of 2013’s Black Flag. It’s a sequel. It is a new game about a new exploration of Edward Kenway’s pirate/assassin journey, set 83 years after the framing sequences of the original game. Resynced provides a new narrative framework that, thanks to the concept of an AI that wants to alter historical memories, arrives with creative justification to tweak a now-classic 13-year old game. That makes Resynced, already a hot seller, a tantalizing hint of where Ubisoft could go with a line of Assassin’s Creed remakes. They could remake the first game, the Ezio games, even the recent ones set in ancient Egypt and Greece. And for each, they could not just modernize the graphics and controls but expand and alter their sequences of events to use them as reference points for a conflict set in the late 21st century, as rival factions try to weaponize historical memories. Game File is a reader-supported publication. To receive new posts and support my work, even when that work consists of ravings about Assassin’s Creed’s modern day plot, please consider becoming a free or paid subscriber. Subscribe A story most players will probably miss If you didn’t know any of this, I’m not surprised. If you played the game and still didn’t catch it, I’m not a bit shocked. If Ubisoft has no plans to do more of this, I won’t fall down. Almost all of what I’ve described is optional and missable in Black Flag Resynced. I nearly missed it myself, as I planned for a breezy playthrough of an old Assassin’s Creed favorite. Instead, I found myself in a 40+ hour hunt for the “real” story, buried deeper in Resynced than any gold-filled chest. The story of 2096 is Resynced’s meta-story, told in two remote pockets of the game: 1) four optional playable “rifts” that players may find as they proceed through Resynced’s pirate fantasy , 2) in dozens of text files tucked three menus deep in the game’s barely-interactive Animus hub. Assassin’s Creed games have almost always had a meta-story about people in the 21st century (usually matching the game’s release year) and their connections to the main history portions you play. Those meta-stories have always been squeezed into the margins, though seldom as severely and as, uh, graphiaclly simple, as in recent games. Back in 2013, the modern-day exploits of you as an Abstergo Entertainment employee were prominent. They were portrayed via first-person portions that occasionally interrupted the third-person Kenway experience and could be explored for hours, complete with their own missions, side quests and puzzles. Resynced’s 2096 story—of Assassin “Watchers” vs. Abstergo/Tempar goons, of rogue AIs, of panicking scientists, of a woman wondering why her Animus-addicted husband is muttering about Mary Read (“What does he mean by Assassins?”), of a fight for the population’s hearts and minds via varying interpretations of Edward Kenway’s life choices—is mostly told through unlockable text files. The files are interesting. Offered via diary entries, intercepted chats and news reports, they present varied perspectives of a world in crisis. One set works as a narrative puzzle as it reveals the Rashomonic interpretations of a massacre, or was that a successful Assassin hit? Another favorite reveals the rising bitterness of a person who, through Edward Kenway’s journey, now shakes at the ignored evil around him. One surmises that Ubisoft is averse to putting the Assassin’s Creed’s meta-story in the way of more marketable pirate playgrounds and ninja/samurai epics. Instead, we get a better-than-nothing text-in-menus approach introduced in 2025’s Assassin’s Creed Shadows. In Shadows, players unlocked the meta-story text files largely via time-gated missions that called on the user to kill X number of enemy type Y, clear three enemy castles, re-win a three-phase fighting tournament, and other grinds. Time restrictions on accessing these missions and unlocking the files meant it could take players months to access the full story in-game. But even in the most hardcore Assassin’s Creed hangouts, the fanbase instead seemed to throw up their hands rather than grind to keep up. In Resynced, Ubisoft has shown some mercy, diminishing the amount of new text files that are tied to timed grinds. Now, most of the text-based 2096 lore are associated with “data file” collectibles that players can find in the world. That includes a batch of written entries that explain a historical link between the feudal Japan era in Shadows and the piracy adventures in Black Flag. Players who explore a lot will find dozens of data files, though the game does not appear to offer any in-game tracker for finding each one. You just need to keep looking for them. As of this writing, I have most of them, but not all. I can’t find any full guide for them online. And even Ubisoft’s optional $5 microtransaction that reveals lots of items in-game does not appear to reveal the locations of the text files (at least the official description omits them from its collectibles list). That’s not a huge bother, because tracking the data files down compelled me to re-explore the waves and islands of Black Flag. That was a thoroughly pleasant task to do for the first time in a dozen years. I expect many players, though, will be content to wait for the files to be reproduced in an online AC wiki somewhere, the easier to read on a web page. It may not seem enticing to play a video game in order to gradually unlock pages of text to read. Why not, you may ask, just read a book, where they put the pages in order? For one, they’ve not tucked this latest installment of Assassin’s Creed’s meta saga in a book. I also enjoy the unordered delivery, the dawning comprehension of a story about 2096’s desperate people and questionable tech, which I glimpsed first at its middle, then the end, then the front, then other moments in between1. I am also enamored with the idea of the Assassin’s Creed games I’ve previously played, including Black Flag, being repurposed for an information war. The ideas in Resynced’s meta-story, which builds off characters and ideas in Shadows’ chunks of text, are strong. The potential of where they could go with it is exciting. As for the pirate stuff? Looks great, controls pretty well, is fun to play and oh so speedy in terms of how much of a good time you can have with each sit-down. It never gets old to chase a new shanty page across a rooftop, bombard a fort with upgraded mortars or use a diving bell to explore sunken wrecks (hats off to the team at Ubisoft Barcelona that worked on the underwater portions in Resynced; that team is now facing layoffs, such is the misery of modern gaming and oft-troubled Ubisoft). New pirate missions in Resynced involving new ally characters are brief, dramatic and add more to Edward’s story, even if the gameplay perks they provide barely enhance the gameplay. A new denouement for high-class pirate Stede Bonnet is affecting; a new hunt for Blackbeard’s treasure is a welcome extra moment. A new epilogue to hunt down a pirate killer, on the other hand, over-complicates Kenway’s character. The ending credits remain my favorite of any game I’ve ever played. Black Flag provides great source material. The revisit is well-made and a great sign of what could be. It is offered in a different wrapper that hints at an opportunity for more interesting remakes to come, should Ubisoft choose to pursue such treasures—and as we brace to resist or comply with an Abstergo future. 1 The messages that Edward Kenway finds in bottles tell another out-of-order story, one about a man reckoning with the strange memories and voices he’s heard in his head since he was a boy. That tale was also in the 2013 game and develops into one of Black Flag’s most compelling character arcs. In Resynced, it has lost its climax, because the bottle story previously paid off in the halls of the first-person Abstergo Entertainment, which is exclusive to the older game. An altered resolution, written by the 2013 game’s lead writer is fine, doesn’t invalidate the 2013 version, but makes for an inferior final note.
From S&T to Spain: Business student gains global internship experience
Giorgio Panci, a senior in business management systems from Rome, is gaining international experience in Barcelona, Spain, this summer as a digital demand associate intern with SAP, a global software company.
The Quintessential Trump-era Politician
In 2020, I wrote an article about collaboration and collaborators. The title was History Will Judge the Complicit, and it started with the story of two famous East Germans, Markus Wolf and Wolfgang Leonhard, who both landed in East Berlin just after the end of the war. Although they came from very similar backgrounds, the former stuck with the regime, eventually becoming its spy boss; the latter, horrified by the brutal reality of Soviet-style communism, escaped. By way of juxtaposition, I also wrote about Lyndsey Graham and Mitt Romney. These two men also made very different decisions when confronted by Donald Trump’s assault on the ideals that they had both grown up believing: A glance at their biographies would not have led many to predict what happened next. On paper, Graham would have seemed, in 2016, like the man with deeper ties to the military, to the rule of law, and to an old-fashioned idea of American patriotism and American responsibility in the world. Romney, by contrast, with his shifts between the center and the right, with his multiple careers in business and politics, would have seemed less deeply attached to those same old-fashioned patriotic ideals. Most of us register soldiers as loyal patriots, and management consultants as self-interested. We assume people from small towns in South Carolina are more likely to resist political pressure than people who have lived in many places. Intuitively, we think that loyalty to a particular place implies loyalty to a set of values. But in this case the clichés were wrong. It was Graham who made excuses for Trump’s abuse of power. It was Graham—a JAG Corps lawyer—who downplayed the evidence that the president had attempted to manipulate foreign courts and blackmail a foreign leader into launching a phony investigation into a political rival. It was Graham who abandoned his own stated support for bipartisanship and instead pushed for a hyperpartisan Senate Judiciary Committee investigation into former Vice President Joe Biden’s son. It was Graham who played golf with Trump, who made excuses for him on television, who supported the president even as he slowly destroyed the American alliances—with Europeans, with the Kurds—that Graham had defended all his life. By contrast, it was Romney who, in February, became the only Republican senator to break ranks with his colleagues, voting to impeach the president. “Corrupting an election to keep oneself in office,” he said, is “perhaps the most abusive and destructive violation of one’s oath of office that I can imagine.” In the wake of Graham’s unexpected death on Saturday, I wrote about him again. He was, in many ways, the quintessential politician of Trump’s Washington, a man who shifted 180 degrees. Graham had been a fervent American patriot, proud reserve officer and military lawyer; he became one of the most important defenders of a president who believes soldiers are “suckers and losers” and shows no respect for law of any kind. As his politics changed, his language grew coarser and his behavior grew worse: He urged Israel to “level the place” in Gaza, and insulted the Danish prime minister in Munich, prompting a colleague, Senator Elissa Slotkin, to issue an apology. Here’s an excerpt from the article, which you can read in The Atlantic (gift link here) Like his close friend John McCain, Graham believed that America should stand at the center of a broad democratic alliance. The few times I met him were in that context, at the Munich Security Conference or at other European-American gatherings, which he once attended with great regularity. He also took seriously the practice of American democracy at home. In a 2014 conversation with The Atlantic, he described himself as a pragmatic politician who eschewed populist slogans. “I know Washington is broken, but what’s broken about it is everybody yelling and nobody trying to fix it,” he said. “I’m trying.” When Donald Trump first appeared in U.S. politics, Graham recognized him immediately for what he was: the spokesman for an alien ideology, one radically different from the idealistic patriotism that Graham had practiced and preached since childhood. Trump privately mocked the military that Graham loved as nothing but “suckers and losers.” He put falsehoods, cynicism, and personal greed at the center of his politics, while expressing disdain for transparency, accountability, and democracy itself. In 2015, Graham described Trump as a “race-baiting, xenophobic, religious bigot” who should “go to hell.” Also as a “nutjob.” When Trump won, Graham understood, as did so many others, that he would have to make some important choices. For a while, he went silent. In the spring of 2016, I saw him at one of those conferences in Europe. He seemed too depressed to speak. But then, like many other Republicans—and, more important, like many other people who have lived under political occupation or experienced radical regime change—he made the decision to abandon his previous ideals, to bury the patriotism that was once so important to him, and to become, instead, a loud, opportunistic collaborator. As I wrote in 2020, it’s very hard to look in to anyone’s heart and to understand their motivations from the outside. But it does seem that Graham had a deep need to be relevant, to be in the game, to be a player, at any cost. And that, rather than any particular achievement, is what he will be remembered for. Continuing to monitor conflicts of interest, ostentatious emoluments, outright corruption and policy changes that will facilitate outright corruption. (Read my original article, Kleptocracy Inc and check out the SNF Agora Institute chart) June 27 Trump diverted funds from more than 900 projects nationwide—including safety upgrades at national parks—to finance beautification projects around Washington, including $700,000 used to fix a White House walkway. June 28 After a years-long Department of Justice investigation into Abbott Laboratories over its management of a baby formula facility where potentially deadly bacteria turned up enough evidence to criminally charge the firm, top department officials instead opted for a financial penalty—illustrating the department’s move away from strict corporate enforcement under the Trump administration. June 29 Defense Secretary Pete Hegseth stacked the Defense Policy Board—which is charged with providing independent national security recommendations to the Office of the Secretary of Defense—with Trump allies, including tech billionaire Marc Andreessen, who has invested in defense contractors like OpenAI and SpaceX, after purging the panel last year. Trump purchased between $1 million and $5 million worth of stock in Axon—which makes about 90% of US tasers—two weeks before ICE solicited bids for a $220 million taser contract. The White House unveiled limited-edition US passports for America’s 250th birthday, featuring a portrait of Trump overlaid on the Declaration of Independence. June 30 Trump made around $1.2 billion from his various crypto companies last year, including more than $500 million from World Liberty Financial and $600 million from sales of his meme coin. Trump is considering issuing 250 pardons to commemorate America’s 250th birthday. These are expected to be largely doled out through the Office of the Pardon Attorney’s informal network of intermediaries. White-collar defense attorneys say they can typically win pardons for clients for $2 million. Last year, Trump administration officials awarded a no-bid contract worth up to $500 million to Clark Construction for the White House ballroom—negotiations in which the president was directly involved. July 1 The Amazon MGM Studios documentary about Melania Trump earned the First Lady more than $10 million. Trump made hundreds of individual stock purchases worth as much as $12.8 million the day before his announcement pausing “Liberation Day” tariffs for 90 days sent the S&P 500 soaring nearly 10%—one of the largest single-day gains ever. Mar-a-Lago and Trump National Doral saw record surges in revenue during Trump’s first year in office, earning $77.5 million and $121.9 million respectively, compared to average annual revenues of $25 million and $75 million during Trump’s first term. Entities across the Persian Gulf paid more than $300 million to Trump’s businesses last year, including $263 million from the sale of half his stake in World Liberty Financial to a firm backed by Sheikh Tahnoon bin Zayed Al Nahyan, a top UAE royal and brother of the country’s president. Kash Patel failed to properly disclose his stock purchase of a Department of Justice contractor, MicroStrategy, worth up to $250,000 last year, despite laws requiring disclosure within 45 days of the trade. July 2 Trump has been directing administration officials to steer more government contracts—so far worth more than $2.4 billion—to Jeff Bezos’s Blue Origin aerospace firm, after Amazon gave $1 million to Trump’s inaugural fund, donated to the White House ballroom project, and reached a $40 million deal to license a Melania Trump documentary. Alongside the billions he made from cryptocurrency last year, Trump earned millions of dollars from real estate licensing fees, including $21 million from organizations in the UAE and $9.2 million in Saudi Arabia, along with smaller sums from merchandise sales, including $4.7 million from Trump Watches and $35,920 from 45 Guitar, a guitar brand endorsed by the president. House Democrats accused consultants tied to the Trump administration of financial fraud, alleging they gave prospective donors to America250—the bipartisan committee created by Congress to celebrate the nation’s semiquincentennial—the banking and routing numbers for Freedom 250, the White House’s fund for events like the UFC cage fight. Democrats also allege that Freedom 250’s CEO traveled to the World Economic Forum in Davos to solicit donations from foreign government officials and business leaders. The Trump administration’s proposed rollback of gun regulations would lift the prohibition on mailing handguns to individuals, a significant win for GrabAGun—the direct-to-consumer firearm retailer on whose board Donald Trump Jr. sits and in which he holds a 1.1% ownership stake. GrabAGun currently must rely on a middleman to transfer firearms to customers. Trump’s financial disclosure revealed that he made more than 21,000 securities trades during his first year back in office, growing his investment account to at least $858 million across stakes in around 1,600 companies, compared to the 13 total trades Joe Biden made during his entire presidency. July 4 Nearly 1 million people who bought the president’s meme coin—Trump Coin—collectively lost $3.8 billion on the token, while he walked away with $636 million. July 6 Shares of Dell closed up 4.4% after Trump recommended people buy the firm’s computers during a speech announcing the launch of Trump investment accounts for children, boosting the more than $1 million worth of shares the president owns in the company. July 9 Federal Reserve Chair Kevin Warsh named crypto investor and Trump ally Marc Andreessen to a task force aimed at modernizing the Federal Reserve, including rethinking its approach to inflation—a key factor keeping interest rates elevated. Palm Beach International Airport has officially changed its name to Trump International Airport—a move that will require Florida to pay royalties to the president’s family for licensing his name. I was there a few months ago, during a trip to Barcelona. The sculptures were a revelation, I’d never seen so many together before. Each one has its own personality. Enjoy the good weather, if you are lucky enough to have it. History Will Judge the Complicit The Quintessential Politician Autocracy Inc Open Letters, from Anne Applebaum is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe
Spain defender Leon joins London City Lionesses
Spain defender Mapi Leon joins London City Lionesses on a three-year deal following her exit from Barcelona.
Barcelona remain on the lookout for reinforcements in defence
FC Barcelona have turned their attention toward bolstering their defensive line, after having heavily bolstered their attack.This report comes from journalist Achraf Ben Ayad, who claims that the La L...
Layoffs begin at Ubisoft Barcelona following Assassin's Creed Black Flag Resynced launch
"There will not be further mandates for Ubisoft Barcelona, despite the team focusing proposing new AC projects," says affected employee
World Cup 2026: EU lawmakers call for formal investigation into Folarin Balogun 'scandal'
Plus: Englands Anthony Gordon says he took Mexico boss Javier Aguirres foul-mouthed rant as a compliment; Arsenal expected to test Newcastles resolve with a first official bid for Bruno Guimaraes; Lamine Yamal says he hopes to see Julian Alvarez complete a transfer to Barcelona
AC: Black Flag Resynced Devs Celebrating Launch With Layoffs
Ubisoft Barcelona faces cuts at the end of July
Ubisoft Barcelona Celebrates Successful Assassin's Creed Black Flag Resynced Launch With Layoffs
51 Employee's, many of whom worked on Assassin's Creed Black Flag Resynced will celebrate its launch with being laid off.
Barcelona registers highest temperature in 112 years as UK health service urges children and elderly to ‘take weather seriously’
Some stations in Spain recorded temperatures of up to 44C after western Europe experienced the warmest June on record
Barcelona joins Arsenal in the race for Ligue 1 star
Barcelona are the latest club to show interest in Bradley Barcola as the French winger’s future at Paris Saint-Germain remains uncertain during the current transfer window.Arsenal are actively searc...
Simeone Breaks Silence On Talks With Barcelona Target Julian Alvarez
Atletico Madrid manager Diego Simeone has revealed talks he recently held with FC Barcelona target Julian Alvarez in the United States.
Barcelona and Atletico Madrid meet over Julian Alvarez transfer
Barcelona’s pursuit of Julian Alvarez appears to be moving into a decisive phase, with fresh reports claiming that direct contact has already taken place between the Catalan club and Atletico Madrid...
A Defining Moment in Chicago Sports: Chicago Fire FC Acquires Global Football Icon Robert Lewandowski
Poland’s all-time leading goal scorer joins the Fire from FC Barcelona with more than 700 goals for club and country
Harry Kane likely to sign new Bayern Munich contract despite Barcelona enquiry
Barcelona made an enquiry to Kane's representatives and have been informed that the 32-year-old is happy in Munich.
Lewandowski close to Chicago Fire switch
Poland's record scorer is set for a big-money move to the MLS after his departure from Barcelona.
Reece James: England defender confident of playing again at World Cup
Plus: England face prospect of 24 hours worth of flights if they make it all the way to World Cup final; South Korea manager Myung-Bo Hong reportedly quits after disappointing tournament; Robert Lewandowski to join Chicago Fire after leaving Barcelona