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Contract extension marks 'fresh start' for Taylor
Midfielder Fraser Taylor is relishing a "fresh start" under new St Mirren boss Craig McLeish after signing a two-year contract extension. The 23-year-old academy graduate, whose deal now runs to summer 2028, made his first-team debut in 2022 and featured 13 times for the Buddies last season before joining Partick Thistle on loan in January. "I'm really pleased, since the new manager has come in, he spoke to me on the off-season, and his ideas really suit the way I like to play," said Taylor.
PlayStation PC Retreat Is A Mistake, As 18+ Months Late Ports Made Money Without Costing a Single Console Sale
Shawn Layden argues PlayStation’s PC port retreat is a mistake, proving late ports made cash without dropping PS5 sales
SCOTUS protects girls in sports, upholds biological reality
A trans athlete keeps winning girls' state titles in California. The Supreme Court just made sure 27 other states don't have to allow it.
Tennessee transfer infielder Manny Marin commits to Arkansas
Tennessee transfer infielder Manny Marin has committed to Arkansas via the NCAA Transfer Portal. The former Volunteers star made the announcement via his Instagram page. — This story is developing and will be updated. Check back momentarily.
Win Fin, Flow Fork, Speed Sniffer: Specialized launches 'fastest road bike ever made' in the S-Works Tarmac SL9
American brand draws on Formula 1 lap times software to quantify performance beyond just aero and weight
What Seattle World Cup matches mean for Chinatown International District
Local organizers ensured they made no promises to business owners, despite some estimates Seattle would see 700,000 visitors.
Georgia lawmakers give businesses a boost in court battles
A year after overhauling court rules to help companies avoid massive jury verdicts, Georgia legislators have made legal battles easier, shorter and cheaper for businesses.
Company that made a Steam Machine wrap based on Valve intellectual property without asking forced to take it down
Dbrand's Portal-themed Companion Cube wrap for the Steam Machine won't be seeing the light of day for a very good reason.
Action! NSF–DOE Vera C. Rubin Observatory Begins Capturing the Greatest Cosmic Movie Ever Made
The wait is over: NSF–DOE Rubin Observatory, funded by the U.S. National Science Foundation and the U.S. Department of Energy’s Office of Science, is now capturing the cosmos in unprecedented detail, transforming the way we study the dynamic Universe.
Colorado’s workers can’t afford a decline in tourism
By Terrance Carroll Work is about more than a paycheck. It is about dignity, stability and the ability to build a life, to provide for family, to contribute to community, and to move forward with purpose. That is why we should take a closer look at how federal policy decisions, even those made with good […]
Andrew Benintendi sends message with Madeira Field of Dreams donation
Chicago White Sox outfielder and former Madeira High School standout Andrew Benintendi donated to the Madeira Field of Dreams project.
Andrew Benintendi sends message with Madeira Field of Dreams donation
Chicago White Sox outfielder and former Madeira High School standout Andrew Benintendi donated to the Madeira Field of Dreams project.
Ravens’ young core is already showing signs of growth
The Ravens have a new head coach, new coordinators, and a new direction, but much of what has made the franchise successful remains firmly in place.
8-year Cowboys team leader retires after 12 NFL seasons
The Cowboys special teams ace has made a name for himself among the club's fans.
Yankees Promote Cody Bellinger’s All-Star Candidacy Before Tigers Game
The New York Yankees made a social media post concerning left fielder Cody Bellinger.
Justice Sotomayor received concert tickets from Bad Bunny’s label
Justice Sonia Sotomayor received more than $4,000 in concert tickets from a Puerto Rican record label that counts Bad Bunny among its clients, according to a financial disclosure report made public Monday.
Manuel Neuer sets new Germany World Cup record
Manuel Neuer made his 23rd start for Germany at a World Cup, setting a new record for the national team after surpassing Lothar Matthäus and Miroslav Klose (both 22 starts).Julian Nagelsmann named Ba...
The Most Important Business Lesson From Cannes Had Nothing to Do With Advertising
The world's biggest advertising festival just made the case that creative thinking belongs in the boardroom, not just the campaign brief.
Will Andy Burnham’s economic vision make us all better off?
Andy Burnham has made his first major speech since returning to Westminster. He set out his vision for a No10 in the North, for more council house building and repeated his claim that Westminster was “broken”.
Opinion | America Is the Land of Endless Choice, Except in Politics
There’s a case to be made for a two-party system, but what do you do when your party loses its mind?
Supreme Court won't revive Alan Dershowitz's $300 million suit against CNN
Dershowitz had urged the court to reconsider New York Times Co. v. Sullivan. The landmark First Amendment case that made it harder for public figures to win libel lawsuits because it requires proof that an outlet knowingly published something false, or showed a reckless disregard for the truth.
Fox News apologizes for Kevin O'Leary's data center opponents claim
Fox News host Johnny Joey Jones read out an apology on the channel's "Big Weekend Show" after O'Leary made the comments on the show in late May.
Harry Kane likely to sign new Bayern Munich contract despite Barcelona enquiry
Barcelona made an enquiry to Kane's representatives and have been informed that the 32-year-old is happy in Munich.
Three Chiefs Land in CBS Sports Top 100 Players
Patrick Mahomes, Creed Humphrey and Chris Jones each made the list
World Cup: our breakout XI from the group stage ⚡️
They made a name for themselves!The World Cup, even more so with 48 teams, is always an opportunity to discover new players, but also to allow others to truly make themselves known to the general publ...
Never forget how Giannis made our city, Milwaukee, come alive
What a perfect marriage we had between our big-little city and Giannis, a wide-eyed underdog who grew up and carried the Bucks to the mountaintop.
New look, same sole: Charm City Run founder keeps Baltimore moving
In Good Company: Josh Levinson made Charm City Run specifically for Baltimore. For nearly 25 years, the region has loved the business back.
Ingredion plans global Benicaros prebiotic expansion across gut and immune health applications
Ingredion highlights that its recent acquisition of the Benicaros prebiotic is a strong strategic addition to its Healthful Solutions portfolio, supporting the company’s formulation versatility alongside expansion of health-forward and clean label ingredients. The company purchased the patented prebiotic fiber, made from upcycled carrot pomace, from NutriLeads earlier this month. With the deal, Ingredion obtained full ownership of all intellectual property, trademarks, human clinical trials, and know-how related to manufacturing Benicaros.
Opinion: Bring back respect in politics
No matter your party or political persuasion, it is undeniable that American politics has taken on a tenor of anger and pessimism. This national mood has made American politics atoxic stew of rage, discontentment and despair. Many Americans don’t feel that the reforms they would like to see in their government are possible. These...
India’s Yash Raj Films Backs Rusk Media in Vertical Entertainment Push (EXCLUSIVE)
Yash Raj Films has made a strategic investment in Rusk Media, the digital-first entertainment company behind the Alright! TV platform that specializes in original content for Gen Z and Gen Alpha audie...
She traveled to China to see family; different parenting styles
A visit home to China made Grace Cong Sui realize that the parenting habits she'd adopted in the US differed from those she grew up with.
She traveled to China to see family; different parenting styles
A visit home to China made Grace Cong Sui realize that the parenting habits she'd adopted in the US differed from those she grew up with.
I grew up in China, but I'm raising my daughter in LA. A trip back to visit family made me rethink my parenting style.
49ers Insider Delivers Commanders Blunt Reality on Brandon Aiyuk
The Washington Commanders are a side character in the rift between Brandon Aiyuk and the San Francisco 49ers. In recent days, Aiyuk has made it clear that he wants to play for the Commanders.Before the remarks from Aiyuk, there was only reporting of Washington’s interest in the 49ers’ wideout. Nonetheless, that’s slightly changed with the […] The post 49ers Insider Delivers Commanders Blunt Reality on Brandon Aiyuk appeared first on HEAVY.
Philippe Stern, Heir to the Patek Philippe Watch Brand, Dies at 88
In an era of electronic timepieces, he marketed $40,000 handmade watches as status symbols, breathing new life into a struggling industry.
Patriots Made Wide Receiver Change for Drake Maye
The New England Patriots have made a big change at wide receiver to help franchise quarterback Drake Maye. The post Patriots Made Wide Receiver Change for Drake Maye appeared first on HEAVY.
Vallejo: Armed Suspect Arrested After Allegedly Making Death Threats At Business
Police have arrested a man after he allegedly brandished a gun and made death threats to customers at a business in Vallejo, police said Sunday.
Orioles drop series with 6-4 loss to Nats
Kyle Bradish walked five batters, and Washington’s Luis García Jr made the Birds pay in a 6-4 result at Camden Yards.
Efzimfotase alfa demonstrated improvements in bone health in treatment-naïve pediatric patients with hypophosphatasia achieving median difference of 1.67 vs placebo in RGI-C Score at week 25 in MULBERRY Phase III trial
Positive results from the MULBERRY Phase III trial showed that efzimfotase alfa (ALXN1850), an investigational enzyme replacement therapy, demonstrated a statistically significant and clinically meaningful improvement in bone health in children (2 to
Suns Face Miles Bridges Decision After Trade With Hornets
The Phoenix Suns made a change on Sunday after getting swept in the first round of the playoffs.
Falcons Underrated Free Agent Signing Made Significant Impact During Minicamp
The Atlanta Falcons had a very impressive showing from one of their underrated free agent signings.
I found a hidden Google Maps feature that made my Pixel's always-on display useful
A hidden Maps trick worth turning on
Google employee who made nearly $1 million explains why he left
A former Google employee says AI equity, job security concerns, and years of side projects convinced him to leave and build his own company.
International Business Machines (IBM) Is A Top Stock In Billionaire Richard Chilton’s Filings
International Business Machines Corporation (NYSE:IBM) is one of the 10 Best Stocks to Buy According to Billionaire Richard Chilton. Technology giant International Business Machines Corporation (NYSE:IBM) made a key announcement recently when it announced its 0.7-nanometer chip manufacturing technology. This technology is the most advanced chip manufacturing technology in the world. International Business Machines Corporation […]
The great FIRE debate: People who made it work say critics miss the point
"I don't live in a van, eat rice and beans, and I've never given up traveling," said one early retiree. "That's not what the movement is about."
A Guy In Sweden Built An Inline-16 Out Of Volvo Engines And It Sounds Awesome
The 8.1-liter inline-16 engine is not connected to a car, but is made from four 2.0-liter Volvo engines joined together in a line.
GM hires talent from rivals to solve self-driving car problem
GM has made several key executive hires since 2025 and brought back Cruise alums to ramp up its self-driving tech development in personal cars.
Elliot Anderson’s Manchester City transfer arrangements see last-minute change
Adaptations have been made to the final medical checks for Manchester City’s record transfer for Elliot Anderson.The 23-year-old put in an 84-minute shift to help guide England through a highly comp...
Yzerman Explains Why Red Wings Left Traverse City
The post Yzerman Explains Why Red Wings Left Traverse City appeared first on Detroit Hockey Now. The Detroit Red Wings brought to a halt a nearly three-decade tradition this week. The club made the announcement that […] The post Yzerman Explains Why Red Wings Left Traverse City appeared first on Detroit Hockey Now.
MS Comic Con 2026: cosplayers, celebrities and fans unite to celebrate beloved characters
Attendees decked out in costumes and homemade props from their favorite TV shows and movies gathered at the Mississippi Trade Mart for Comic Con 2026
Steve Yzerman on Red Wings' Dylan Larkin trade request
GM Steve Yzerman made his first public comments since Dylan Larkin's request to be traded by the Detroit Red Wings to a contender.
An au pair made my family obsessed with Argentina's World Cup run
What started as childcare turned into a friendship, a World Cup obsession, and a connection that spans two continents.
City of Palms new downtown parking program: How local business react to the change
The Fort Myers City Council recently approved a change impacting parking rates at all three of downtown Fort Myers' parking garages. As it stood, visitors would receive one hour of free parking followed by a hourly rate. Now, the change has made it so visitors are entitled to two free hours followed by a hourly rate. Local business owners and managers said it's a good idea giving visitors more time to bask under the royal palms and indulge in some shopping. But one general manager points out a problem that did not start yesterday, but years prior.
Business owners: The future of downtown is a stronger State Street
Businesses for State Street is made up of business owners and members of the Santa Barbara community. We write to respectfully ask that the mayor and City
Mets Make Roster Decision After 7th Straight Loss
The New York Mets have made roster decisions before game two against the Phillies.
Week in Politics: Trump and bipartisan housing bill, John Bolton; Democratic socialists
President Trump canceled a signing for major housing legislation, former National Security Advisor John Bolton pled guilty to mishandling classified documents, and Democratic Socialists made gains.
NHL Rumors: 3 Red Wings Who Could Be Traded Next
The Detroit Red Wings made a notable trade on Friday, as they traded top goalie prospect Sebastian Cossa to the Utah Mammoth in exchange for the 23rd overall pick of the NHL Entry Draft. The Red Wings then used that pick to select forward J.P. Hurlbert.Seeing Cossa get traded by the Red Wings is not […] The post NHL Rumors: 3 Red Wings Who Could Be Traded Next appeared first on HEAVY.
Browns Warned Over Deshaun Watson Decision
The Cleveland Browns can insist that their quarterback competition between Deshaun Watson and Shedeur Sanders will be decided on the field, but the decision will not be made in a vacuum. The post Browns Warned Over Deshaun Watson Decision appeared first on HEAVY.
Who is the 49ers best player in 2026?
The 49ers have several players that made a preseason Top 100 list.
The Year 536 AD Was So Bad It May Have Been the Worst Time in Human History to Be Alive
Volcanoes, famine and plague made 536 a leading candidate for history’s worst year.
Making sense of what Lars Tiffany’s lawsuit says about UVA sports
Analyzing a few points made by Tiffany’s camp and what they indicate about the UVA athletic department’s approach.
Take an 8-Minute Gameplay Tour of the Remade Havana in Assassin's Creed Black Flag Resynced
Join Assassin's Creed Black Flag Resynced lead level designer Jean Strachen as she takes you on an eight-minute gameplay tour of Havana. See what it looks like now in the gorgeous new remake that will be released for PC, PS5, and Xbox Series X|S on July 9.
Is Mega Skarmory good for Pokémon GO Raids?
Super Mega Skarmory Raid Day brings one of the new Legends: Z-A Mega Evolutions to Pokémon GO, and gives the undeniably cool Skarmory a new lease of life in the Raids meta. A popular / type from Gen 2, Skarmory has been a staple in the Little and Great League formats, but has never made […]
'It's business': 2027 5-star CB on choosing Texas over Texas A&M
2027 5-star CB John Meredith "loves A&M to death" but made a reported business decision in choosing the Texas Longhorns.
YouTube Shorts Nixes 'Dislikes' And Lets You Double The Playback Speed
YouTube has made several key changes to Shorts by removing dislikes and offering a clear screen mode.
Three Chicago Bears make CBS Sports’ Top 100 NFL Players of 2026 List
With the NFL on a break, get ready for list season, and CBS Sports just dropped their Top 100 Players, and three Chicago Bears made the cut.
Matt Rhule hosts youth football camp in Omaha through FlexWork Sports
Matt Rhule and four Nebraska football players made the trek to Omaha Thursday.
It's Xbox's turn (again), as console prices keep going up
Microsoft announced a price hike for the Xbox Series consoles today, the third in little over a year. Effective August 1, the Xbox Series S, which launched in 2020 for $300, will cost $500 in the U.S. The Xbox Series X, which launched in 2020 at $500, will go for $800. This follows a round of PlayStation 5 price increases from Sony this spring, and a slow-motion increase for Nintendo’s Switch 2, which will kick in in the U.S. in September. (Mind you, there were also eight video game industry price hikes in six months of 2025). The chart up top shows the sudden ascent of console prices over the past year, a sudden surge in an already unusual hardware generation. Prices had been flat for years, now “up” is the new “flat.” Game console prices used to go down across the length of a console generation, but not this time around. Microsoft’s explanation for the new price hike today: We hoped another price increase would not be necessary, and we have spent the last several months working with suppliers on options. Unfortunately, console storage and memory prices have increased by more than 2.5x and we expect another doubling by the fall of 2027. The entire consumer electronics industry is struggling with the current components crisis, but the effects are particularly hard on consoles. Unlike phones, computers, speakers, and other consumer devices, consoles are typically not sold at a profit, but instead for less than they cost to make. This is an issue well beyond game consoles. Apple announced price hikes on its computers and tablets today as well. Game File is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe Item 2: Brutal Bungie cuts Bungie laid off “most” of its Destiny development team and some developers who worked on Marathon, the newest game from the struggling Sony-owned studio. A WARN notice issued by Sony to Washington State, where Bungie is based, tallied cuts impacting 292 workers, effective next month. That’s strictly for Bungie/Sony jobs in Washington and wouldn’t account for any elsewhere. The video I clipped below shows the redacted list of Bungie cuts filed to Washington State officials. As you’ll see, I had to scroll for a while… In a note emailed to PlayStation workers and published online, PlayStation game studios chief Hermen Hulst offered the following explanation for these latest cuts at Bungie: This is painful news, especially for talented colleagues whose roles have been eliminated. This decision was made only after extensive discussion and careful consideration, and I want to provide some context on how we arrived here. Over the past several months, together with Bungie leadership, we reviewed the studio’s long-term direction, development priorities, resource needs, and role within our broader portfolio strategy. We explored multiple alternatives before concluding that a reduction was necessary to align the studio’s resources with its current priorities and long-term goals. In 2022, Sony bought Bungie for $3.7 billion. The studio’s marquee game, the multiplayer live service shooter Destiny 2 was losing popularity at the time. Its next game Marathon, released earlier this year, has been well-reviewed but had a slow start. Bungie is renowned for making great shooter games, and Destiny fans have mourned the wind-down of Destiny 2. They’ve also expressed bewilderment over reports that Destiny 3 is not, per Bloomberg, immediately in the cards.
Caitlin Clark made the WNBA bigger. It’s still playing small
The league’s paltry one-game suspension of Alyssa Thomas after her fist to Caitlin Clark's throat barely begins to address the problem.
Dolly Parton makes surprise appearance — complete with a joke
Dolly Parton just made a surprise appearance, complete with her trademark humor, amid health issues.
Octavia Spencer's Orit Entertainment Names New Heads Of Film & TV
Octavia Spencer's Orit Entertainment has made two key executive hires, naming Kathryn Tyus-Adair as Head of Film and Adam Wagner as Head of Television
Octavia Spencer’s Orit Entertainment Names Kathryn Tyus-Adair Head Of Film & Adam Wagner Head Of Television
EXCLUSIVE: Octavia Spencer’s Orit Entertainment has made two key executive hires, naming Kathryn Tyus-Adair as Head of Film and Adam Wagner as Head of Television. “Kathryn and Adam are exceptional exe...
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
Romeo Doubs' Exit Could Raise the Stakes for Jordan Love in Green Bay
Jordan Love and the Green Bay Packers are eyeing a bounce-back campaign in 2026. The Packers opened the 2025 season with a strong start, posting a 9-3-1 record through their first 13 games, before a flurry of injuries derailed Green Bay's Super Bowl hopes. Since taking over as Green Bay's starter under center, the Utah State product has shown flashes of a top-five signal-caller, though the team hasn't yet made it past the divisional round under his leadership.
Reflecting Pool liner was cut with knife or razor, National Park Service says
A parks official made the statement in a court document filed late Wednesday
Reflecting Pool liner was cut with knife or razor, National Park Service says
A parks official made the statement in a court document filed late Wednesday
Reflecting Pool liner was cut with knife or razor, National Park Service says
A parks official made the statement in a court document filed late Wednesday
Spent 3 days at Acadia National Park; biggest mistakes we made
We spent a few days exploring Acadia National Park in Maine. Next time we go, we'll make reservations and avoid mistakes like packing the wrong shoes.
Waterloo's Grout Museum District to demolish its Bluedorn Science Imaginarium amid funding changes
This summer, the Grout Museum District is preparing to demolish its former science center, the Bluedorn Science Imaginarium. The decision was made in the face of funding uncertainty stemming from property tax reform in Waterloo.
Fox Sports renews Gold Cup rights, adds Nations League
Fox Sports is going to remain a player in the international soccer game for several more years to come. Although the rights for the 2030 World Cup are up for grabs, Fox made the announcement on Wednesday night that the Gold Cup, the CONCACAF championship tournament, will remain with the company. In addition, Fox is…
An Update from PlayStation Studios
Below is an internal email from Hermen Hulst, CEO, Studio Business Group, Sony Interactive Entertainment distributed today to SIE employees. ********************************************************************************** Dear Team, Today I want to share a difficult update regarding Bungie. We have made the decision to reduce Bungie’s workforce, affecting a significant number of employees, including most of the Destiny team and some Marathon team members. There are also reductions across SIE teams that support […]
Supreme Court strikes down law limiting guns in businesses
The justices nixed a Hawaii law that made gun owners get permission to bring guns into certain establishments.
Scientists Analyzed the Bones of ‘Skeleton Lake.’ What They Found Made No Sense.
Roopkund Lake sits in a frozen pocket of the Himalayas where hundreds of people died across a millennium. So why did researchers find bones from the island of Crete there?
David P. O'Brien
About five years ago, David P. O'Brien had a comfortable position at Marsh & McLennan Cos., where he held the top post at the financial giant's Louisville, Ky., office. Despite the lofty rank, Mr. O'Brien found himself longing to be at a smaller company that had to work a little harder to land business. That desire led him away from Kentucky five years ago and to Cleveland, where he serves as executive vice president at business insurance agency Oswald Cos. "I left Marsh before it was en vogue," he said, referring to layoffs and defections at Marsh over the course of this year that followed accusations of bid rigging at the big firm. Above all, Mr. O'Brien, 38, wanted to work at a company that relied on its inventiveness, rather than its name, for business. He said he has found that at Oswald. "It causes you to be more creative, to be more resourceful," Mr. O'Brien said. For instance, an Oswald client seeking to do business internationally might be directed to the network of offices abroad run by competitors such as Marsh and Aon Risk Services Inc. "We're going to use whatever access into the market that makes the most sense for our clients," he said. Of course, using such a strategy can be dangerous for Oswald if its client decides to further a business relationship with one of the firms Oswald recommended. "That's the obvious question and why it's nontraditional," he said. "I think if we're good, and if we're bringing value to the client, then there's no risk. I'm not threatened by it." Imaginative business solutions of that type made his career move to Oswald from Marsh worthwhile. "It's very much a challenge," he said. "It helps you keep your edge. I'm all for the competition." John Jacunski, currently vice president and corporate controller at York, Pa., paper company PH Gladfelter Co., met Mr. O'Brien four years ago when Mr. Jacunski was at WCI Steel Inc. in Warren. So impressed was he with Mr. O'Brien's work for WCI that Mr. Jacunski has retained the Oswald executive at PH Gladfelter. "He's a young guy for the position he has, but he's done a great job for us," Mr. Jacunski said. Among his roles at Oswald, Mr. O'Brien leads the firm's client retention efforts and also serves as director of its property and casualty group. "You don't have the same human resources," he said of the job jump to Oswald. "You don't have, obviously, the safety net a big company has." But sometimes, it can be difficult to ascertain individual contributions when working at a big company. "I wanted to be able to see the end results of my work and my efforts," Mr. O'Brien said.
Dolly Parton Makes Surprise Appearance Following Health Issues
Dolly Parton made a surprise appearance at the grand opening of her travel stop in Tennessee just one month after she canceled an upcoming Vegas residency due to health concerns.
As Trump kicks off state fair festival, he once again says Iran war is ‘done’
The president made his declaration before a mix of locals and tourists at a scaled-down version of the event after some performers canceled.
Revealed – Warhammer: The Old World Made to Order miniatures
Classic baby Dragons, Ogres, and more return to the World of Legend.
By Refusing to Sign a Bipartisan Housing Bill, Trump Made It Clear That He Doesn’t Care About Everyday Americans
What’s the president’s priority instead? Passing his voter-suppressing SAVE Act to keep his cronies in power.
21 small products that made a huge difference in our lives and are cheaper than ever
Our favorite small, budget-friendly products have made a big difference in our lives, and they’re heavily discounted for Amazon Prime Day.
Reese Witherspoon makes first public appearance with boyfriend Oliver Haarmann
Reese Witherspoon made her first public appearance with financier boyfriend Oliver Haarmann at the 'Elle' premiere in New York City.
Houston Methodist receives $110M donation, largest in health system’s history
The donation, made by The Brockman Medical Research Foundation, is the largest in the hospital system's history.
Oracle's Headcount Fell by 21,000 as AI Reshapes Its Business. Here's What It Means for the Stock.
The job cuts made headlines. But the bigger story is what's funding them.
Sony Pictures Entertainment Invests $100M In Cosm, Operator Of "Shared Reality" Venues
Sony Pictures Entertainment has made a $100 million strategic investment in Cosm, a venture-backed operator of "shared reality" venues.
From The Sports Desk: Cristiano Ronaldo makes history and joins in World Cup scoring barrage
Ronaldo scored twice yesterday against Uzbekistan, which made him the first player to score in six World Cups, from 2006 through this tournament.
From The Sports Desk: Cristiano Ronaldo makes history and joins in World Cup scoring barrage
Ronaldo scored twice yesterday against Uzbekistan, which made him the first player to ever score in six different World Cups, from 2006 through this current tournament.
‘We’re witnessing the end of the America that made our lives possible’: author Eddie Glaude on US’s 250th birthday
Glaude’s new book shows political turmoil historically reaching its boiling point around Fourth of July celebrations
Dozens in Florida among hundreds charged in a DOJ crackdown on healthcare fraud
The two-week operation uncovered more than $6.5 billion in false claims submitted to insurers, according to the Department of Justice. Nearly two dozen arrests were made by state authorities.
Nuggets Trade No. 26 Pick To Spurs on Draft Day
The Nuggets made a last-second trade on draft day.
United Airlines debuted cheaper Polaris business class fares
United Airlines just made some lie-flat business class seats cheaper on long-haul flights, but there's a catch. What to know about the new Polaris base fares before buying.