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USA TODAY Sports announces National High School Esports Championship
USA TODAY Sports, in collaboration with PlayVS, announced the USA TODAY Sports National High School Esports Championship.
Iowa Business Council survey shows postive outlook on state's economy
The Iowa Business Council (IBC) has released its third quarter Economic Outlook Survey that gauges the outlook for the next six months. IBC President Joe Murphy says it’s based on a 100 point scale. “Our overall survey score was 64.91 index points, so just under 65 points, relatively flat, virtually no movement on the overall […]
Proposal would add properties to downtown Business Improvement District
More properties would pay into the downtown Business Improvement District, or BID, in a proposal being considered by the City Council.
The evolution of sports analytics: A Q&A with UNC Charlotte expert Michael Schuckers
The field of sports analytics continues to become increasingly important across all sports. From the court to the turf, UNC Charlotte students are getting hands-on experience and helping teams make winning decisions. Michael Schuckers, a professor in the School of Data Science, has extensive experience in sports analytics, consulting for teams in the National Hockey […]
Zeldin announces EPA proposal to support cleaner air and business growth in Arizona
EPA Administrator Lee Zeldin visited Arizona Tuesday to announce proposed approval of Maricopa County Rule 204, an emissions-reduction program intended to help businesses invest and expand while improving air quality. The announcement followed a roundtable with business leaders and elected officials. Rule 204 would allow qualifying voluntary emissions reductions from nonroad engines and equipment to […]
HHHunt names next CEO
HHHunt announced that current CEO Buck Hunt will step down from the position on July 1, 2027, and that Ann Kelly will succeed him.
Stephen A. Smith issues apology over controversial Lane Johnson mental health take
Following Eagles right tackle Lane Johnson's retirement announcement, figures across the NFL called out Smith for how he discussed the news.
Sonic Racing: CrossWorlds DLC ‘Avatar Legends Pack’ launches October 14
Sonic Racing: CrossWorlds downloadable content “Avatar Legends Pack” will launch on October 14, SEGA announced. It is also available as part of the $29.99 Season Pass.
Discover Long Island revamps website for visitors, locals
Discover Long Island has launched a redesigned website aimed at providing an immersive and user-friendly experience for both visitors and locals. The site incorporates AI-driven features, improved navigation and local storytelling to showcase Suffolk County and regional attractions, with plans to add international translations and itinerary-building tools in the future.
South Carolina State Fair announces new attractions, food and entertainment
The South Carolina State Fair will return Oct. 15-25 with more than 60 rides, new food and entertainment options, and a new performance area at the fairgrounds.
South Carolina State Fair announces new attractions, food and entertainment
The South Carolina State Fair will return Oct. 15-25 with more than 60 rides, new food and entertainment options, and a new performance area at the fairgrounds.
Nobel Prize winner was a Carolina postdoc - College of Arts and Sciences
Kenso Soai, who received the Nobel Prize in chemistry for solving a century-old chemical mystery, conducted research in the chemistry department in the College of Arts and Sciences.
Exclusive: Inside Trump's AI science summit
The White House is announcing more than $1 billion in industry commitments.
New AI trade group launches with focus on health sector
A new trade group launched this week to give artificial intelligence companies in the health, human services and life sciences worlds a collective voice in anticipation of state government writing …
Everything announced at Microsoft’s Surface Laptop Ultra event
Check out our coverage of the show.
Novant Health reduces retirement match amid cost pressures
Novant Health announced changes to its retirement benefits Tuesday that will take effect starting next year.
The Moth Project using music, myth, science and art to share story of migration
Renowned show comes to Henderson Fine Arts Center on Oct. 23
Report: Iowa economy seeing ‘positive change’ this year
The Iowa Business Council (IBC) has released its third quarter Economic Outlook Survey (EOS) for 2026. That survey is showing encouraging signs for Iowa businesses, according to IBC officials. The Iowa Business Council (IBC) is a nonpartisan, nonprofit organization whose 22 members are the chief decision makers of the state’s largest employers. Since its establishment […]
Scientists uncover how the world's smallest flowering plant became so tiny
A new study has revealed how some plants pack the same structures as larger species into a tiny space, making them promising candidates for future crops.
ChatGPT for Teens keeps teens talking, even during mental health crises
ChatGPT’s teen safeguards are meant to protect vulnerable users, but new testing found the chatbot continues encouraging engagement during crises and potentially encourages unhealthy relationships with the AI itself.
CCDPH Launches “Spread Facts, Not Flu & COVID” Campaign Ahead of Respiratory Virus Season - Cook County Department of Public Health
Today, Cook County Department of Public Health launched Building Healthier Communities 2030, suburban Cook County’s Community Health Improvement Plan. The plan was announced together with Cook County Board President Toni Preckwinkle, Cook County Department of Public Health, community organizations, healthcare providers and cross-sector partners. Building Healthier Communities 2030 serves as both a collective vision and a practical roadmap that will guide public health efforts across suburban Cook County through 2030.The plan aligns with President Preckwinkle's Policy Roadmap and reflects a shared commitment to advancing health equity through coordinated, community-informed action.
People on weight-loss drugs report fingernails falling off as researchers uncover surprising link
Nail discoloration was reported by 46% of GLP-1 users versus 17% of non-users, while scalp inflammation accompanied hair loss in most medication users studied.
Biohub launches $1.8 billion AI biology initiative in major science push
Biohub, Google, Meta and the U.S. government are investing $1.8 billion to build AI-ready biological data for disease research.
ESPN's 2027 Super Bowl telecast will stream on Disney+
The Super Bowl is coming to Disney+. The Walt Disney Co. announced Wednesday that ESPN's telecast of the NFL's marquee event on Feb. 14 at SoFi Stadium in Inglewood, California,
‘Positive thoughts’: Legendary WWE announcer reveals new health setback
Jim Ross, a longtime professional wrestling announcer, has revealed a new health setback months after brain surgery.
‘Positive thoughts’: Legendary WWE announcer reveals new health setback
Jim Ross, a longtime professional wrestling announcer, has revealed a new health setback months after brain surgery.
Sony Pictures Entertainment Launches Crunchyroll Storyworks, Aiming To Boost Japanese Anime
Sony Pictures Entertainment has unveiled a new division of its Crunchryroll subsidiary, Crunchyroll Storyworks, which will look to boost Japanese anime.
A$AP Rocky Launches 4-Year Scholarship For First-Time Freshmen At Roc Nation School of Music, Sports & Entertainment At Long Island University
Rapper and entrepreneur A$AP Rocky is paying it forward.
Four NYC Health + Hospitals Skilled Nursing Facilities Named Among Newsweek's Best Nursing Homes in America
NYC Health + Hospitals announced that four of its skilled nursing facilities ranked in the Top 10 in New York State in the Newsweek Best Nursing Homes
Elanco, Purdue announce westside research institute
The One Health Research Institute will help speed up the path from discovery to products.
CDC sees low plague risk, monitors Siberia arrivals after worker death, director says
Centers for Disease Control and Prevention Director Erica Schwartz said on Wednesday the risk to the US from an unconfirmed pneumonic plague case in Siberia was extremely low, but the agency was prepared to monitor and screen travelers.
New nonprofit launches campaign to preserve local newspapers
The Mount Desert Islander, Ellsworth American and Bangor Historian have formed a nonprofit, Acadia Newspaper Trust, to transition the newspapers from private, for-profit ownership to nonprofit ownership.
Chase Adds Payroll to Larger Business Banking Offering
Chase is expanding its payroll service to help business clients dealing with cash flow pressures. The new offering, announced Wednesday (Oct. 7), brings
Spartz Named Health Care Legislator of the Year
MUNCIE, IN — Congresswoman Victoria Spartz (IN-05) was named Legislator of the Year by the Indiana Primary Health Care Association (IPHCA) at its annual conference in Muncie.
Developer leaves family RE firm to launch AI venture
Michael T. Puntillo leaves PX4 Development to start DPI Enterprise, an AI company focused on real estate operational systems.
Why the best HR chiefs understand the business
HR pros should know the business’s priorities beyond the people function’s scope.
Oct. 7 reshaped Israel. Three years on, its political map remains largely unchanged.
As Israelis head to the polls, analysts say Oct. 7 and the war that followed have hardened existing political divisions rather than fundamentally changing them.
Some furloughed Star Wars Zero Company developers are returning to work, studio says
Bit Reactor, the Maryland based company, behind this summer’s well-received tactical combat game Star Wars Zero Company says that “more” of its team is returning to work after being furloughed ahead of the game’s release. This is the studio’s first statement on the matter since Game File’s August report that “most” of the development team had been furloughed—technically kept as employees, but without pay or benefits—a few weeks prior to launch. Some of those furloughs ended this week. “This week, we started the process of returning more of our team back to work at Bit Reactor, an important step forward in our continued support for Zero Company, “ Bit Reactor CEO Greg Foertsch said in a statement. He continued: “Having to ask team members to step away after we navigated unexpected business developments outside of our control and so close to launch was an incredibly difficult decision, but one that was necessary to help us eventually bring as many people back as possible. “This team means a tremendous amount to me, and I am incredibly proud of what we have accomplished together. Thank you to our fans for the incredible response to the game and for supporting us along this journey. We look forward to sharing more updates regarding Bit Reactor and Zero Company soon.” Game File reported in August that Bit Reactor had retained a small team to work on updates for Zero Company. One person familiar with the situation told Game File that the returns announced today bring the studio’s pay-rolled headcount to more than half of what it had been ahead of the furloughs. That means a considerable number of people have been brought back, but that a fair number also remain without pay. While companies in the U.S. are often legally required to publicly disclose how many people they’ve laid off, furloughs can often be kept private, for a time. The United States Department of Labor requires companies to publicly report mass furloughs if they meet specific criteria, including any expectation that they will last more than six months. For those game makers who remain furloughed by Bit Reactor, it’s now been about two months. For more about Bit Reactor, the furloughs, the studio’s back-story and the ongoing lawsuit that brought this to light, read my August report. [ ‘Most’ of Star Wars Zero Company studio Bit Reactor was furloughed ahead of launch ](https://www.gamefile.news/p/star-wars-zero-company-bit-reactor-furloughs-lawsuit) Stephen Totilo · Sep 1 Last week was meant to be a moment of triumph for Bit Reactor, the Maryland-based game studio founded in 2021 with ambitions to create a great new tactical combat game. [ Read full story ](https://www.gamefile.news/p/star-wars-zero-company-bit-reactor-furloughs-lawsuit)
UT Launches Institute for the Future of Business to Address AI, Tech Changes in Business and Education
The Institute will convene leaders, researchers, educators and students to explore the immediate and long-term implications of groundbreaking technologies.
deGrom’s Late Collapse Clouds His Future With Rangers
Jacob deGrom faces an uncertain Texas Rangers future after a costly late-season slide, forcing his payroll-strapped team to weigh his veteran leadership against a massive contract.
Folsom Lake Symphony opens season with Berlioz
FOLSOM — The Folsom Lake Symphony launches its 2026-27 season with a passionate and dramatic opening night program, 7:30 p.m. Saturday, Oct. 10, at Harris Center for the Arts.
Orange County to Take Over Mental Health Campuses, Ends Nonprofit Partnership
It’s unclear what the next steps are for one of the county’s biggest mental health nonprofits after they ceded control of their facilities to the county government.
Sharing moments of exceptional care from nurse turned patient at Intermountain Health St. Vincent Regional Hospital
“Can I be your nurse today?” Those words came as a comforting surprise to Jen Paulson as she awaited one of the most uncertain days of her life. As a nurse for 22 years at Intermountain Health St. Vincent Regional Hospital, she knows the role well. That morning she was preparing for a double mastectomy surgery after an unexpected breast c...
Albany council, mayor start public engagement on 2027 budget
The council has set dates for public hearings and a possible vote, while the mayor will hold public meetings.
‘He Has a Bigger Problem,’ ‘Embarrassed The Business’ — NFL Legend Terrell Owens Has No Sympathy For Tony Romo After Controversial CBS Exit
Terrell Owens has little sympathy for Tony Romo following the former Dallas Cowboys quarterback’s sudden departure from CBS Sports. The network announced on Friday that it had mutually agreed to part ways with Romo after nine years in the broadcast booth, bringing an unexpected end to one of the biggest analyst careers in recent NFL history.
Ex-Cagliari and Tottenham defender Vega running for FIFA President
Former Cagliari and Tottenham Hotspur defender Ramon Vega announced he intends to run as a candidate for FIFA President against Gianni Infantino.The 55-year-old played his international football for S...
Flutter Entertainment (FLUT), Why Is It Back In The Spotlight?
Executive Change Puts Flutter’s Governance In Focus Flutter Entertainment (NYSE:FLUT) has announced a senior legal transition, with Chief Legal Officer Don Liu resigning on September 30, 2026, and Group Company Secretary Edward Traynor stepping in as interim CLO from October 1. Flutter Entertainment’s share price has shown only a modest 0.7% move over the past day and a 2.4% gain over the week, yet the 30 day share price return is down 23.8% and the year to date share price return has fallen...
State investing over $17M in mental health service grants
Governor Josh Stein and the state Department of Health and Human Services made the announcement today.
CurTec Expands Operations in Oconee County
CurTec USA (CurTec), a high-performance packaging manufacturer, today announced it is expanding its operations in Oconee County. The company’s $10 million investment will create 10 jobs. Founded in 1991, CurTec produces plastic drums, pails and...
ESPN's Super Bowl 61 broadcast to also stream on Disney+
ESPN announced on Tuesday that its broadcast of Super Bowl 61 will also be streamed on Disney+. Disney+ will stream the ESPN/ABC broadcast as well as the Spanish-language telecast on
ESPN's Super Bowl 61 broadcast to also stream on Disney+
ESPN announced on Tuesday that its broadcast of Super Bowl 61 will also be streamed on Disney+. Disney+ will stream the ESPN/ABC broadcast as well as the Spanish-language telecast on
ESPN's Super Bowl 61 broadcast to also stream on Disney+
(AP) — ESPN announced on Tuesday that its broadcast of Super Bowl 61 will also be streamed on Disney+.Disney+ will stream the ESPN/ABC broadcast as well as the Spanish-language telecast on ESPN Deportes in the United States.
Encinitas is paradise. Why can its politics get so hostile?
In 2024 Encinitas elections, the mayor and two City Council members won by promising to fight development. What will voters do in 2026?
Search committee named for next dean of the Klingler College of Arts and Sciences
The national search follows the July 2025 announcement that Dr. Heather Hathaway, professor of English, had been named acting dean.
Amazon US Prime Deals: the Samsung Galaxy S26 Ultra is 30% off
Despite the recent price hike that put the base model at $1,400 MSRP, you can still get an S26 Ultra under $1,000. The Samsung Galaxy S26 Ultra launched at...
Wells Fargo faces regulator probe over efforts to boost black homeownership, WSJ reports
The Donald Trump administration's housing officials are launching a probe into Wells Fargo over programs and commitments the bank made nearly a decade ago to increase homeownership among Black Americans, the Wall Street Journal reported on Wednesday.
Three Bucksport residents vie for two town council seats
Bucksport voters will have a choice of three candidates for two open town council seats on Nov. 3: Incumbent Mark Eastman and newcomers Jon Goss and Ralph Chapman.
Newsom announces latest films awarded California tax credits
Thirty-five films were awarded credits
Your 2026 NFL Week 5 announcing schedule
The 2026 NFL London Games continue in Week 5, when the Philadelphia Eagles and Jacksonville Jaguars meet on Sunday. Dave Pasch, Kurt Warner, and Jason Kelce will be in the Tottenham Hotspur Stadium booth for the second straight week on NFL Network (9:30 a.m. ET). Kevin Burkhardt and Tom Brady will have the Fox call…
Redesigned MacBook Pro will reportedly include these three changes
Apple has a fully redesigned MacBook Pro launching soon, its first new design since 2021. Here are three design changes reportedly coming.
Adelphi awarded $982K for no-cost entrepreneurship program
Adelphi University secured a $982,000 grant to launch the Adelphi Entrepreneur Experience, a no-cost program designed to equip students and local entrepreneurs with skills to develop startups in high-growth and public service sectors across in the New York region.
Disney+ enters NFL streaming with Super Bowl, two more games
Add another streaming platform to the NFL slate. ESPN and Disney+ announced plans to stream the Super Bowl and other NFL games.
Indie Selects for October 2026: Discover and Progress Through Unforgettable Worlds
For October, the ID@XBOX team invite you to discover mysterious realms, conquer new challenges, and uncover stories waiting to be told.
NYC Health + Hospitals Leaders Named to Becker's 2026 "Rising Stars: 188 Healthcare Leaders to Know Under 40" List
NYC Health + Hospitals announced that Komal Lodaria, Senior Director of System Care Experience, and Christopher G. Wilson, MSN, RN. Chief Nursing Officer,
Tony Fadell on why the first wave of AI gadgets failed — and what comes next
The “father of the iPod” says the first generation of AI gadgets failed to solve real problems — and the next wave will need to earn consumers’ trust.
Getinge Life Science president is leaving
Swedish medtech company Getinge announced today that the president of its Life Science business is resigning to pursue an external opportunity.
Nvidia Takes Aim at Intel’s $32 Billion PC Business With Microsoft’s Surface Laptop Ultra
Microsoft (MSFT:NASDAQ) and Nvidia (NVDA:NASDAQ) are set to unveil the Surface Laptop Ultra in San Francisco on Wednesday, October 7, with Satya Nadella and Jensen Huang taking the stage together. The laptop runs on Nvidia’s RTX Spark chips, announced in June, and it’s built to run AI agents on the PC itself instead of in the cloud.
Google experiments with an AI-powered gaming platform
Google Labs is working on a new AI-powered game-creation platform called Playground for users to build browser-based games using simple text prompts.
Rose Brand Acquires IWEISS, Bringing Together Complementary Expertise For The Future Of Live Entertainment
Two major companies have joined forces: Rose Brand and IWEISS have spent more than a centu | Rose Brand has announced that it has entered into an agreement to acquire IWEISS, bringing together two highly respected companies with decades of experience serving the entertainment, performing arts, event, and architectural markets.
Microsoft Surface and Windows Event 2026: All the Announcements and Analysis Live From San Francisco
Today's the day! We hope to learn fresh details about the Surface Laptop Ultra, the next chapter for Windows, and the future of Copilot at Microsoft's fall event. Follow along with all of our expert commentary and on-the-ground updates, and tune in to the livestream later this afternoon.
Aviva launches US specialty business
Aviva on Wednesday launched Aviva Specialty, its U.S. specialty insurance platform, based in New York.
Spotify Camp Nou to host Pedro’s farewell following retirement announcement
FC Barcelona icon Pedro Rodriguez has announced his retirement from professional football at the age of 39, bringing an end to a 20-year career. The former Barcelona forward, who enjoyed the most succ...
Accel Entertainment Announces Third Quarter 2026 Earnings Conference Call and Webcast
Accel Entertainment will announce third-quarter financial results on November 3, 2026, followed by a conference call and webcast.Quiver AI SummaryAccel Entertainment, Inc. announced that it will release its financial and operating results for the third quarter ending September 30, 2026, on November 3, 2026, after market close. The Company will hold a conference call and webcast at 4:30 PM ET to discuss the results, featuring CEO Mark Phelan and o
Food Entrepreneurs Get A Free Crash Course In Growing A Business
At the inaugural CT Food Business Lab, hosted at SCSU and organized by CitySeed, the Hispanic Federation, the Urban League, and CT Food Launchpad.
Ring's first smart lock can be hand-cranked when its battery dies
Amazon-owned Ring is entering the smart lock market with a device designed to tackle a common concern: getting locked out when the battery dies
Ring announces its first smart lock, solving a major pain point for smart home users
Today, Amazon’s Ring subsidiary is announcing its first ever smart lock. It solves a key problem that looms over many...
Google's new SynthID website can identify AI-generated media
Google on Tuesday launched a new site that lets anyone verify whether a piece of media, be it an image, a video or an audio clip, is generated using AI.
Vector Science and Therapeutics Corp. Announces Collaboration with SAFE Investment in Gary Payton's Scoreboard
/PRNewswire/ -- Vector Science and Therapeutics Corp. (TSXV: PAIN) ("Vector" or the "Company") today announced that it has entered into a strategic...
Report: Iowa economy seeing ‘positive change’ this year
The Iowa Business Council (IBC) has released its third quarter Economic Outlook Survey (EOS) for 2026. That survey is showing encouraging signs for Iowa businesses, according to IBC officials. The Iowa Business Council (IBC) is a nonpartisan, nonprofit organization whose 22 members are the chief decision makers of the state’s largest employers. Since its establishment […]
Another personal AI assistant has launched — Meet Tab, which emerged from stealth with a $300M valuation
A new personal AI assistant has arrived. Meet Tab, which announced Tuesday that it had officially emerged from stealth.
Dealroom.co | IIPR launches Series B preferred stock sale to fund life science loan
What's the deal? Innovative Industrial Properties (NYSE: IIPR),…
Leaked images reveal Apple’s new Home smart lock, thermostat, more for LG
Apple has reportedly co-developed new Home accessories to launch under LG branding, and leaked images reveal our first look at the products.
LIBN announces 2026 Hall of Fame inductees for Long Island business leaders
Long Island Business News reveals the 2026 Hall of Fame inductees honoring top business leaders shaping the region's future.
At Black business expo, officials urge owners to 'speak up'
Black small business owners are facing economic conditions similar to those they dealt with as a result of COVID-19, Black Economic Council of Massachusetts CEO and President Nicole Obi said
metaphactory by Digital Science now available on SAP® Store
Digital Science today announced that its metaphactory is now available on SAP® Store, the online marketplace for SAP and partner offerings.
University of Lynchburg to launch online Master of Science in Counseling programs
In January of 2027, the University will launch the online Master of Science in Clinical Mental Health Counseling and Master of Science in School Counseling programs.
Naples Comprehensive Health Names Danny Hogan Chief Financial Officer
Naples, Fla., Oct. 07, 2026 (GLOBE NEWSWIRE) -- Naples Comprehensive Health (NCH) announced today that Danny Hogan has been named its next Chief Financial Officer. Hogan joined the organization on Oct. 5. Hogan brings extensive health care finance and operational leadership experience to NCH. He previously served as Chief Financial Officer, Shared Services and Integrated Operations, at Bon Secours Mercy Health, a $14 billion nonprofit health system with 47 hospitals across the United States and
Business Council tours Southern Tier manufacturer during National Manufacturing Week
Universal Instruments in Conklin was the fourth stop on an 11-site statewide tour
The 2026 Nobel Prize in Physiology Went to a Technique That Lets Scientists Control the Brain With Light
Neuroscientific advances follow a pattern of visualizing the brain, measuring its function and then controlling it. Optogenetics may lead to a new era of medical treatment.
Tecsys Pledges $5 Million to Prisma Health's New Behavioral Health Hospital
Tecsys Inc. (TSX: TCS), a leading provider of supply chain management solutions for health care and distribution, announced a $5 million pledge to support the new Prisma Health Behavioral Health Hospital in Upstate South Carolina. The gift,...
Davis Polk Welcomes Prominent Media & Entertainment Partner Glen Mastroberte in Los Angeles
NEW YORK, October 07, 2026--Davis Polk announced that prominent entertainment lawyer Glen Mastroberte joined the firm as a partner in the Mergers & Acquisitions practice in LA.
Health Council recommends high-dose flu vaccines for over-65s for first time
Belgium's flu vaccination campaign begins next week, on 15 October. This year, for the first time, the Superior Health Council (SHC) recommends a high-dose flu vaccine for people over 65.
C21 launches D2C Entertainment Summit with Audience First focus as entertainment business transforms
C21Media has launched the D2C Entertainment Summit, which will run as a track within Content London, Content Americas and Content Europe and as a standalone one-day event in London during June 2027.
C21 launches D2C Entertainment Summit with Audience First focus as entertainment business transforms
C21Media has launched the D2C Entertainment Summit, which will run as a track within Content London, Content Americas and Content Europe and as a standalone one-day event in London during June 2027.
Unity unveils a web-based AI game creation platform
Unity Spark will launch later this year on Google Playground
Tecsys Pledges $5 Million to Prisma Health's New Behavioral Health Hospital
/PRNewswire/ -- Tecsys Inc. (TSX: TCS), a leading provider of supply chain management solutions for healthcare and distribution, announced today a $5 million...
Gastro Health and House Rx Announce Launch of Medically Integrated Dispensing
/PRNewswire/ -- House Rx, the leader in medically integrated dispensing solutions for specialty care clinics, and Gastro Health, one of the nation's largest...
AMO Pharma in Collaboration with Population Health Research Institute (PHRI) and Venca Research Inc. Announces FDA Advice on Potential Phase 3 Development Path for AMO-02 in Treatment of Arrhythmogenic Cardiomyopathy (ACM)
/PRNewswire/ -- AMO Pharma Limited ("AMO Pharma"), a privately held clinical-stage specialty biopharmaceutical company focusing on rare genetic disorders with...