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Two's company: ISTA scientists identify new class of star remnants
In the vastness of the Universe, any new object with interesting properties can spur the search for similar objects, potentially establishing a new class of stars. In a paper published in Astronomy & Astrophysics and an arXiv preprint, researchers from the Institute of Science and Technology Austria (ISTA) describe two stellar remnants that share five properties, including X-ray emission, despite being isolated objects. According to the team, these two remnants are sufficient to define a new class of stars.
Alaska Airlines unveils its first-ever International Business Class Suites experience, setting a new standard for long-haul travel
Debuting this spring, the airline’s new long-haul Business Class marks a major step in Alaska’s transformation into the West Coast’s global carrier.
Delaware YouTube star talks buying a 'house' and being 'class clown'
New Castle County native Chris Klemens didn’t invent the man on the street style of interviewing, but he's been doing it for well over a decade.
Donation-based Pound Fitness class in Moundsville raises awareness of women’s heart health
The beat of drumsticks and music filled Miller Chiropractic and Wellness Center in Moundsville on Monday evening as women took part in a donation-based “Pound F
Sherman Oaks Notre Dame baseball wins National Classic opener
Benett Pace homers for Sherman Oaks Notre Dame in a 7-4 win over Corona Santiago during the first day of the National Classic.
Stage, Screen, and Sound: April Arts and Entertainment Picks
April is really turning out to be a musical month in Buffalo! From K-Pop, Jazz, looping Scottish Folk Music, and classic rock, there is something for everyone. Check out the events below to hear all the great sounds Buffalo has to offer. And if you need a laugh, John Mulaney is coming to Shea’s on April 3 (after selling out April 2). Get a ticket before it’s too late. We will see you out and about this city this month.
NFL partners with TMRW Sports and world-class investors and athletes to launch new professional flag football league
The NFL announced today that it is partnering with TMRW Sports to develop and operate a professional flag football league for women and men. The new professional league will launch with support from a broad and influential investor pool, including NFL clubs, established institutional and strategic investors, and current and former NFL players.
Are insurance premiums tax-deductible? How to write off business insurance
ERGO NEXT reports that business insurance premiums can be tax-deductible, depending on their classification by the IRS.
Zack Polanski meets unions in attempt to get them to switch party funding to Greens
Leader understood to have spoken to 10 trade unions after party claimed working class voters are turning to them
Schreyer Scholar explores entrepreneurship through computer science
Schreyer Scholar Aryan Sabnekar first learned coding from an online course during the COVID-19 pandemic. Since then, he has continued to explore all of his interests in coding and entrepreneurship both inside and outside the classroom at Penn State, most recently placing at HackPSU.
Clemson scientist wins Governor’s Award for expanding science access
BeakerBox provides middle school classrooms with ready-to-use, inquiry=based science lessons that meet state education standards.
The 'Ballet Reign' YouTube channel brings Gen Z vibes to the art form
The whimsical YouTube channel Ballet Reign posts explainer videos about classic ballets and dancers, bringing edgy, fun Gen Z vibes to an art form known for attracting an older crowd. The online response is effusive and growing.
‘The Count of Monte Cristo’: Will Jeremy Irons Be Back as Abbé Faria?
The Oscar winner made his debut in Episode 2 of the 'Masterpiece' adaptation of the literary classic.
Support beyond the classroom: Little Rock’s community schools offer health care, therapy, a student bank and more
At first glance, Chicot Elementary is just like any other school. But walk past the bright hallways plastered with crayon drawings and "I can count to 100" worksheets and through a gym lined with balance bikes, and you'll find clinics that provide vaccines, lab work, eye tests, counseling and language interpretation for Little Rock School District students and their siblings.
High school sports results for Sunday, March 29, 2026
SUNDAY’S RESULTS Softball WPIAL CLASS 5A Section 4 Baldwin 3, Connellsville 2 RIPKEN EXPERIENCE At Pigeon Forge, Tenn. Yough 10, Martin County, Ky....
Mid-Ohio Valley Spring Sports: Ripley baseball goes from hunter to hunted
RIPLEY — Ripley has gone from the hunter to the hunted. That’s what happens when you win a state championship return and eight starters. The Vikings finished 27-5 last season, blanking Frankfort 5-0 in the Class AAA state final. “It’s a completely different mindset this year,” said Ripley head coach Shane Casto. “We’ve got the […]
Kevin Harvick Surprised with News That He's a NASCAR Hall of Fame Nominee
Kevin Harvick's next stop might be in Charlotte. He was one of 15 people named as a nominee for the NASCAR Hall of Fame as part of the Class of 2027.
Bronstein, Gewirtz & Grossman LLC Urges AMC Entertainment Holdings, Inc. Investors to Act: Class Action Filed Alleging Investor Harm
Nationally Recognized Firm Urges AMC Investors to Explore Class Action Representation
📚 The Inoculation Project 3/29/2026: Kindergarten Books, Art Meets Science
This week, we’re helping a kindergarten teacher�in San Bernardino add�some books to her classroom, and a rural Michigan science teacher slide a little art into her science lessons. �We hope that ...
MT AG: Ronan High School teacher brings traditional practices to science classes
A science teacher at Ronan High School is introducing traditional ecological knowledge to teach students about sustainable agriculture and land stewardship.
Why Most Quantum Computers Need to Be Colder Than Space
Quantum computers promise to revolutionize whole industries by outperforming classical computers on complex calculations. They just need to be colder than the coldest natural place in the universe.
11 Cool New Gadgets to Keep on Your Radar
Catching you up on the past week’s most notable product releases.
Retro Recap: All The Classic Gaming News From The Past Week (March 29th 2026)
Wind Waker! Sonic X-treme! Evercade!
Hingham Schools Eye Business Curriculum Expansion as Class Size Concerns Mount
HINGHAM - March 23, 2026 - The Hingham School Committee moved to modernize its high school offerings Monday night, reviewing a comprehensive plan to expand the “small but mighty” Business Department while simultaneously grappling with data that places Hingham as an outlier in elementary class sizes. Director of Social Studies Andy Hoey presented a two-year program review that highlighted the department’s success in community partnerships but warned that high student demand is testing current staffing limits. Meanwhile, committee Chair Jen Benham presented independent research showing Hingham is the only benchmark district with second-grade classes hitting a 25-student cap, sparking a directive for the Policy Subcommittee to review class-size standards. Editors note: South Shore News is going paid in April, subscribe now to make sure you don’t miss a story. Reach out for group or organizational pricing. Subscribe The Full Story The meeting opened with a look into the future of Hingham High School’s (HHS) curriculum. Andy Hoey, who oversees the Business Department, presented the first formal program review for the department since 2009. [15:09] Hoey characterized the department as a vital elective hub that currently serves between 14% and 27% of the HHS student body in any given year. [31:31] “We are very proud of our business department here at Hingham High School... while we’re very proud of it, we are always striving to make improvements and enhancements.” [15:55] — Andy Hoey, Director of Social Studies A key highlight of the presentation was the announcement of a new AP Business with Personal Finance course launching next year, pending enrollment. [20:08] The review team found that while the program is “well-aligned” to national standards, it remains a high-school-only offering. Hoey outlined an action plan to explore “vertical articulation,” potentially introducing business or financial literacy units at the middle school level to fill a “gap” identified between fifth and eighth grade. [41:48] However, the department faces “smoke and mirrors” regarding student GPA, according to Hoey. Currently, most business courses are “unleveled” and do not count toward a student’s GPA, which survey data suggests may deter some students from enrolling. [28:15] The committee discussed the possibility of offering Honors or College Prep (CP) credit for advanced courses, such as investing or marketing, to better reflect their academic rigor. [38:27] The discussion took a sharp turn toward elementary education during an enrollment update. Superintendent Dr. Katie Roberts noted a net gain of four students mid-year, but it was Jen Benham’s “rabbit hole” data analysis that caught the committee’s attention. [50:35] Benham researched 13 benchmark towns—representing 34 elementary schools—and found that Hingham was the only district with a second-grade section reaching 25 students this year. [51:36] Benham’s findings suggested that while many districts lack formal class-size policies, Hingham’s current cap of 25 for second grade may be too high. “I think if we could at least have 23 at a cap for grade two,” Benham suggested, noting the importance of that grade level for literacy development. [53:09], [54:55] Dr. Roberts cautioned that smaller classes require more staff, which is a significant hurdle following a budget season where nine general education positions were cut across the district. [55:56] The committee also finalized the 2025 Town Report, which was updated to be more “student-centered” and highlight staff early in the document. [11:12] Additionally, a series of food service policies were approved to align with Massachusetts’ universal free school meal mandate, including new protocols for meal modifications due to allergies or religious needs. [59:23] Share Why It Matters The meeting underscored a tension between Hingham’s desire to offer elite, specialized programming and the foundational pressure of class sizes. The expansion of the Business Department—including potential Microsoft certifications and AP courses—aims to prepare students for a “real world” where credit scores and financial literacy are paramount. [46:20] However, the revelation that Hingham’s second-grade classes are larger than those in all neighboring benchmark towns suggests a potential strain on early education that could impact long-term student performance if not addressed by the Policy Subcommittee. Official Minutes & Data Key Motions & Votes Motion: To approve the Hingham Public Schools 2025 Town Report. [13:16] Vote: Unanimous (7-0) ([01:13:28]) Motion: To approve the Memorandum of Agreement (MOA) for summer counselor work regarding course placement. [57:33] Vote: Unanimous (7-0) ([57:50]) Motion: To approve Policy EFBA (School Food and Nutrition/Meal Modifications). [01:00:32] Vote: Unanimous (7-0) ([01:00:44]) Motion: To approve Policy EFC (Universal Free School Meals). [01:00:54] Vote: Unanimous (7-0) ([01:01:07]) Public Comment No members of the public spoke during the meeting or via the remote link. [01:02:30] What’s Next The Policy Subcommittee will take up the review of elementary class-size caps over the next year to determine if the Grade 2 limit should be lowered from 25 to 23. [52:18] The Business Department will monitor enrollment for the new AP Business course and continue exploring dual-enrollment partnerships with Quincy College. [38:13] Source Video: Harbor Media South Shore News is a reader-supported publication. 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Disney opens World of Frozen at renamed Paris park in 2 billion euro expansion
f i e business amusement-parks entertainment world-news general-news | WBEN
Prep Sports Report: Beechwood teams sweep 9th Region All "A" Classic baseball, softball titles
By Terry Boehmker NKyTribune sports reporter Beechwood won 9th Region All “A” Classic championship games in baseball and softball this week to earn state tournament berths in both small school playoffs. On Thursday, the Beechwood softball team defeated St. Henry, 17-0, in the region final to take the title for the second time in four...
Detroit 'Dreamgirls' event to feature Jennifer Holliday, Raven-Symoné
Orsa Music Hall event will serve as launch of ODX, a new event that seeks to create immersive movie experiences for classic films.
Demetrious Johnson joins 2026 UFC Hall of Fame
Demetrious Johnson will be immortalized in the UFC Hall of Fame as part of the 2026 class.
Florida high School football recruiting rankings: Top 2027 prospects
As the spring sessions kick off, here is a look at the top class of 2027 recruits ahead of the Florida high school football season.
John Jacobs: Put students, not politics, first in Alabama classrooms…
We can, and should, get back to the basics of ensuring Alabama’s classrooms remain places where students come first. Our children deserve nothing less. |…
Hills-Beaver Creek doubles up titles with Class A basketball championship to go with nine-man football
The Patriots, who were led by Jamin Metzger with 22 points and 13 rebounds, dominated Janesville-Waldorf-Pemberton to win the Class A basketball title.
Internationals: Florian Wirtz shows his class with Germany performance
Internationals Showcase Liverpool Influence as Wirtz and Van Dijk ShineLiverpool’s presence on the international stage continues to underline the club’s global reach, with Internationals providing...
Chattanooga Times Free Press
Chattanooga's only daily newspaper. Complete coverage of breaking news in Chattanooga, Other local, regional and national news. Classifieds and online marketplace.
Cruel Science Teacher Tried To Sabotage A Student’s College Prospects, So Student Fought Back And Embarrassed Her In Front Of The Whole Class
Looks like this cruel teacher had finally met her match.
Big League Chew Builds 2026 Ambassador Roster Around Baseball, Softball, and Entertainment Culture
Key Takeaways Big League Chew names five brand ambassadors for 2026, spanning youth baseball, professional softball, women's baseball, and entertainment Mo'ne Davis, the first girl to win and pitch a shutout in the Little League World Series, headlines the class Jocelyn Alo, the NCAA Divis
Florida football hosting key recruits this weekend for spring visits
Florida football hosts top recruits for a key March visit weekend that could have major effects on the Gators' first class under Jon Sumrall.
Jarrod Bowen replacing Mo Salah is classic Liverpool
Jarrod Bowen to replace Mo Salah at Liverpool? It's a classic move from the Reds - and FSG.Mo Salah will leave Liverpool at the end of the season, bringing an end to nine wonderful years at Anfield. H...
From The Magic Faraway Tree to 5 Seconds of Summer: your complete entertainment guide to the week ahead
Enid Blyton’s classic kids’ fantasy novel gets the big-screen treatment, while the Aussie boyband hit the UK’s arenas
Classic clash
Blair County’s Makenna Weimert makes a pass over Central Pa.’s Zayona Thomas during the girls game of the 19th annual Altoona Mirror Basketball Classic. Mirror photo by Patrick Waksmunski
New material science facility
The 150,000-square-foot building sits in the center of campus and provides classrooms and labs for materials science
Three Berkeley Lab Researchers Named AAAS Fellows
Three scientists, Blake Simmons, Abby Dernburg, and Felix Fischer, have been elected into the 2025 class of AAAS.
Understanding protein motion could greatly aid new drug design
For many of us, “protein” is the key element of a food order. However, beyond your preferred choice of meats or plant-based alternatives, proteins encompass a large class of complex biomolecules whose chemical structure is encoded in our genes. Proteins have critical functions in living cells: They help repair and build body tissues, drive metabolic reactions, maintain pH and fluid balance, and keep our immune systems strong.
Rumor: Zelda: Ocarina of Time remake and new Star Fox game coming this year, no 3D Mario until 2027
Insider NateTheHate has provided an update on a variety of Nintendo projects, including rumors about Zelda remake, a new Star Fox game, and the lack of a 3D Mario in 2026. This comes from a new podcast published today. It’s claimed that Star Fox will be making a return on Nintendo Switch 2 this summer. Apparently it’ll be a classic...
The Patriots are banking on a youth movement in Foxboro
The Patriots going to the next level in 2026 will depend on Mike Vrabel’s first draft class getting its opportunity.
Does Saka Deserve More Empathy?
First of all, I should clarify that I have always viewed Bukayo Saka as overrated. A good player, but not world-class, as some Gooners would have you believe. Certainly, he is young enough to develop ...
Walking a tightrope between a global brand and traditional football: Why Como 1907’s entertainment machine is sustainable, unlike RB Leipzig’s
Como 1907 is causing a stir in Serie A. The Lombardy-based club, which just a few years ago was languishing in the lower reaches of Italian football, is on the verge of qualifying for the Champions League. At first glance, this rapid rise may seem like a classic ‘football fairy tale’, but behind it lies a calculated strategy, a pile of money – and a surprising amount of sustainability.
See United's new Polaris business class with doors and a 'Studio'
United's new Polaris business class got a long-awaited facelift with sliding doors. Though the doors will remain open for now, pending certification.
See Louisiana’s ‘Vote for the Crook’ election through the eyes of 8 new Hall of Fame inductees
The eight inductees to the 2026 class of the Louisiana Political Hall of Fame played a role in the epic 1991 governor’s race between Edwin Edwards and David Duke.
High school sports results for Thursday, March 26, 2026
THURSDAY’S RESULTS Baseball CITY LEAGUE Carrick 13, Brashear 6 Obama Academy 27, Perry 0 (3) WPIAL CLASS 5A Section 1 Franklin Regional 13, Penn...
KDE, Kentucky Science Center to host Day of Science for Community-Based Educators in May
The Kentucky Department of Education is hosting a Day of Science Learning for Community Based Educators on May 7 from 9 a.m. to 4 p.m. ET at the Kentucky Science Center in Louisville. The event is mainly for organizations who provide science learning experiences for students outside the classroom. Attendees will learn about high-quality instructional resources
Vermont Sports Hall of Fame adds two members to 2026 induction class
South Burlington tennis legend Jake Agna and 1909 University of Vermont grad Fenwick Watkins join 2026 Vermont Sports Hall of Fame induction class.
Danish twins, Nicolai and Rasmus Højgaard, commit to the 2026 Zurich Classic
Nicolai and Rasmus Højgaard have committed to play in the upcoming Zurich Classic, tournament officials announced Thursday.
Four Ohio State scientists elected to 2025 class of AAAS Fellows
Four scientists at The Ohio State University have been elected to the 2025 class of American Association for the Advancement of Science (AAAS) Fellows.The AAAS Fellowship, recognizing scientifically or socially distinguished efforts to advance science or its applications, is one of the most prestigious honors a U.S. scientist can receive. Fellow...
Ten Johns Hopkins researchers named American Association for the Advancement of Science Fellows
The 2025 class of American Association for the Advancement of Science fellows includes 449 scientists, engineers, and innovators spanning 24 scientific disciplines who are being recognized for their scientifically and socially distinguished achievements
Four-star cornerback Danny Lang commits to USC
After a somewhat slow start, the Trojans’ 2027 recruiting class is quickly heating up
Fourteen Emory faculty named Fellows of the American Association for the Advancement of Science | Emory University
A record number of Emory faculty have been elected to the newest Class of AAAS Fellows in recognition of outstanding efforts to advance science.
Good Morning, Nashville! Talking Immigration Data Politics at Vanderbilt University
After a busy day on Capitol Hill yesterday, I landed in Nashville, Tennessee, last night for an exciting two days on campus at Vanderbilt University. Carwil Bjork-James, an anthropologist whose creative use of database construction to support critical scholarship resonates strongly with my own work, generously invited me to give a talk today about the politics of immigration data and to join a Wikipedia edit-a-thon tomorrow on the topic of immigrant detention. I encourage you to check out Carwil’s database project “Ultimate Consequences” about political deaths in Bolivia after 1982, and his book The Sovereign Street: Making Revolution in Urban Bolivia. My talk today is titled “Untangling the Messy Politics of Immigrant Detention Data.” I’ll focus on how immigrant detention data (not just detention centers themselves) become sites of controversy—from the collection and classification choices that shape what we can know, to the strategic withholding and distortion of data for political ends. Drawing on research spanning multiple administrations, I’ll trace how current data controversies in the second Trump administration connect to long-standing tensions in how we measure, interpret, and communicate about immigration. My goal is to move beyond simple partisan narratives and offer a practical guide for anyone working with immigration data to explore both the pitfalls to avoid and the creative opportunities for more transparent, rigorous public communication about immigration realities. If you are on campus, please stop by. Tomorrow I will join Carwil and Vanderbilt students for a Wikipedia Edit-a-Thon to edit and update Wikipedia entries related to immigrant detention with the latest robust information and data. This event is designed to orient participants into how to edit on Wikipedia, provide them with data-driven starter templates on detention facilities, and allow each person to produce an initial article on one element of the network of ICE facilities or one death in custody this year. The workshop is also a demonstration of how to use open data sources to build public knowledge—something I am deeply passionate about. Thank you to Vanderbilt University, the Spatial Histories series, and Carwil for hosting me. I would love to be a part of conversations and workshops related to immigration data on your campus. Students are really eager these days to have informed, critical, and data-driven explorations of our current immigration system. Reach out anytime if you want to discuss the possibility of bringing me to your campus. Subscribe
Brevard on a budget: Free, fun things to do this weekend, March 27-April 2
On a budget? Free, fun things to do in Brevard this weekend include classic cars, concerts and a pirate festival.
High school sports results for Wednesday, March 25, 2026
WEDNESDAY’S RESULTS Baseball WPIAL CLASS 5A Section 2 Bethel Park 8, Upper St. Clair 6 Franklin Regional 12, Penn Hills 2 (5) South Fayette 9, Moon...
Notre Dame lands commitment from 4-star RB Lathan Whisenton
The Notre Dame Fighting Irish have landed a commitment from 4-star RB Lathan Whisenton, a prominent RB in the 2027 class.
FOX Sports Assembles Top-Tier Roster for 2026 MLB Regular Season Coverage
After an enthralling World Baseball Classic, FOX Sports returns to the 2026 Major League Baseball season with a dynamic roster of broadcasters.
Young scientists, engineers grow with UH support | University of Hawaiʻi System News
Science fair projects provide an opportunity to extend classroom learning.
Trump showed off a classified map during a 2022 plane trip, Raskin alleges in letter
President Donald Trump showed off a classified map on a 2022 flight to his New Jersey golf club and held onto a record from his first term that was so sensitive only six people would have had access to it, according to a letter released Wednesday by a top House Democrat.
"The Hall of Fame Knocks: Class of 2026" nominated for Sports Emmy | Pro Football Hall of Fame
“The Hall of Fame Knocks: Class of 2026” has been nominated in the Outstanding Edited Sports Special category as part of the 2026 Sports Emmy Awards.
Democrats revive allegations around Trump classified document case in latest political battle with Justice Department
Democratic Rep. Jamie Raskin asserted in a new letter that recently released Justice Department files show that prosecutors once considered whether President Donald Trump had improperly retained classified material relevant to his business interests after his first term.
18 Fort Collins-area athletes earn all-state honors for winter sports
18 Fort Collins-area high school athletes earned winter all-state honors, including three who were named Player of the Year in their sport and class.
Jaguars open 75K-square-foot business office at One Tower Court in downtown Jacksonville
The Jacksonville Jaguars on Wednesday opened a 75,287-square-foot business operations office at One Tower Court, downtown Jacksonville’s first multi-tenant Class A office building built since 2007. The team occupies the building’s second through fourth floors.
NASA Awards Astrophysics Postdoctoral Fellowships for 2026
The highly competitive NASA Hubble Fellowship Program (NHFP) recently named 24 new fellows to its 2026 class.
New records in Trump documents case raise concerns over business conflict, US lawmaker says
Newly released records in the now-dismissed classified documents case against U.S. President Donald Trump raise fresh concerns over national security risks and potential private business motivations, the top Democrat on the House Judiciary Committee said.
Jaguars Cut Ribbon on New Business Headquarters at One Tower Court
Downtown’s Newest Class-A Office Building Also Celebrates Opening for Downtown YMCA Branch, Announces Timucuan Asset Management and Foley & Lardner LLP as Tenants
Glyphosate: A story of science, risk, and nuance
In the summer of 2014, a California groundskeeper named Dewayne Johnson started noticing patches of raw, weeping skin spreading across his body. He had spent years applying Roundup, Monsanto’s glyphosate-based herbicide, for a school district, sometimes drenched in it when equipment malfunctioned. By 2014, he had a diagnosis: non-Hodgkin’s lymphoma. In 2018, a jury awarded him $289 million in damages, later reduced on appeal. Tens of thousands of lawsuits followed. The story hasn’t quieted down. It’s all over the internet, swinging between “this will kill you, buy organic” and “relax, you’re fear-mongering.” Some of that recent chatter stems from an Executive Order protecting glyphosate and its production, which set off intense infighting within the MAHA movement. Some of it reflects a deeper truth: Americans genuinely care about harmful chemicals in their environment (see poll below). And the conversation isn’t going anywhere, with a Supreme Court case involving Monsanto set for this April. Glyphosate (the active ingredient in Roundup) is one of the most widely used herbicides in the world. But does glyphosate cause cancer? And how much exposure is actually risky? With so much mistrust in institutions and corporations (and some genuine conflicts of interest), making sense of the actual scientific evidence is genuinely hard. Here is a translation of what the scientific evidence actually says. Does glyphosate cause harm? Glyphosate is an herbicide that kills most plants it contacts rather than targeting specific species. It works by blocking an enzyme pathway (EPSPS) that plants and many microorganisms need to produce essential amino acids. Without those amino acids, the plant can’t grow and dies. Glyphosate was first developed by Monsanto in the 1970s and became ubiquitous after the company introduced “Roundup Ready” crops in the 1990s. In 2024, Bayer removed glyphosate from residential Roundup-branded products due to litigation pressure. But today it is still the most widely used herbicide in the world. Farmers also discovered they could spray it directly on crops like oats, lentils, beans, and peas just before harvest to dry them out faster and make harvesting easier. Because of its widespread use, it’s obviously really important to understand if it’s harmful to humans. The key principle: The dose makes the poison The most important concept in toxicology is that “the dose makes the poison.” Sixteenth-century physician Paracelsus articulated what remains the foundational principle of toxicology: sola dosis facit venenum. Water will kill you if you drink enough of it. Aspirin saves lives at 81 milligrams and causes internal bleeding at higher chronic doses. So, at what dose is glyphosate poisonous? The LD50 in rats (the dose that kills half the test animals) is around 5,600 mg/kg body weight. Table salt is roughly 3,000 mg/kg. By that classic measure, glyphosate is less acutely toxic than salt. But some people are exposed to a lot of glyphosate through their work. And among the general public, there are many questions about low-dose, cumulative exposure from multiple sources over long periods. Does glyphosate cause health problems? Cancer Correlation maps are striking, with one analysis finding that 60% of counties that spray the most glyphosate have non-Hodgkin’s lymphoma rates above the national average. But correlation alone doesn’t establish cause, which is why animal and human studies matter. In animals: Rat studies are typically what most fear is rooted in, but most people don’t know the study details on the dosage given to rats. A pooled analysis of the 13 most rigorous rat studies found evidence that very high doses, around 55,000 times greater than typical food residue exposure, can cause certain cancers. In humans: One of the strongest studies followed 55,000 herbicide users over 20 years and found no overall increased cancer risk. There was one signal: among those with the highest use, rates of acute myeloid leukemia (AML) appeared elevated. A broader meta-analysis of 18 human studies also found no overall cancer risk, though a separate meta-analysis focused specifically on non-Hodgkin lymphoma found that people with high cumulative glyphosate exposure faced a 41% higher relative risk compared to those with low or no exposure. These human studies are observational studies (randomized controlled trials would be unethical), and meta-analyses are only as reliable as the studies they pool. But the story seems consistent: at very high exposure levels, there may be some cancer risk. But that’s about as far as the science currently takes us. Emerging research: gut and reproductive health Gut: Because glyphosate targets a pathway that exists in some gut bacteria, scientists have questioned whether it could affect the microbiome. In mice, a 2023 University of Iowa study found that glyphosate altered gut bacterial composition and raised markers of intestinal inflammation. A 2024 systematic review found similar patterns: disrupted gut bacteria and problems with the mucus layer that protects the intestinal wall in mice. Whether this translates to humans is an open question. The human gut is highly variable and resistant, and we don't yet have strong studies confirming the same effects in people. Reproductive health: Animal studies have found that glyphosate-based herbicides can interfere with reproductive hormones, including disrupting egg cell development in mice and reducing the number of eggs available in sheep’s ovaries. However, the doses used in these experiments were high, so it’s not yet clear whether the same effects would occur in humans. On the human side, a 2021 pilot study led by Mount Sinai researchers tested urine samples from pregnant women across the U.S. and found glyphosate in 95% of them. The study also found a possible connection between higher glyphosate exposure during pregnancy and a subtle physical difference measured in female newborns. That said, some connections weren’t statistically reliable and this was a small study. The researchers themselves said more and larger studies are needed before drawing firm conclusions. What do regulators say about glyphosate safety? In 2015, the International Agency for Research on Cancer (IARC), part of the World Health Organization, classified glyphosate as "probably carcinogenic to humans" (Group 2A). The classification is worth taking seriously. But, there’s an important distinction: IARC classifies hazard, meaning the potential to cause harm under some conditions. It does not assess risk, which accounts for actual exposure levels and the real-world probability of harm. The U.S. EPA, the European Food Safety Authority, Health Canada, and regulatory agencies in Australia and Japan have all concluded that glyphosate is “unlikely to be carcinogenic to humans” at realistic exposure levels. They’re asking a different question: given how much of this people actually encounter, what is the probability of harm? Your actual exposure is what determines your actual risk. What does glyphosate mean for your daily life? At the grocery store: Food residues are small. The EPA’s acceptable daily intake is 1.75 mg/kg of body weight per day. To hit that threshold from oatmeal alone, a 150-pound adult would need to eat roughly 50 pounds of oats every day. But this calculation addresses only one pathway (food), and we don’t yet have robust tools to measure people’s actual total exposure. If reducing exposure matters to you, organic certification prohibits synthetic herbicides, and organic oat products generally test at lower or undetectable levels. Either way, a diet rich in whole grains, conventional or organic, is far better for your health than one that omits them out of fear of residues. On the farm: Occupational exposure is orders of magnitude higher than consumer exposure. Farmers and farm workers who mix, load, and apply glyphosate-based herbicides, especially without protective equipment, face meaningfully different risk profiles. Proper PPE isn’t optional. Integrated weed management strategies that rotate chemical modes of action are also worth taking seriously, both for health and for long-term effectiveness. If you live near a farm: Spray drift is real. Concentrations near field edges can spike during and after application, particularly on windy days. This is an area where I think public health could really step up and empower rural communities with buffer zones, rather than placing the onus on individuals. But for now, knowing your local agricultural calendar and keeping windows closed during application are the first steps. Bottom line Dewayne Johnson was exposed to glyphosate at levels most people will never encounter, and a jury decided he deserved compensation. That outcome is not evidence that the oatmeal in your pantry is dangerous. But it is a reminder that the dose, the context, and the person doing the exposing all matter enormously. Glyphosate is a chemical tool with benefits, trade-offs, and genuine open scientific questions. Learning to hold that complexity without collapsing into panic or dismissal is, honestly, one of the most useful and hardest things to do in navigating modern health science. Love, YLE Your Local Epidemiologist (YLE) is founded and operated by Dr. Katelyn Jetelina, MPH PhD—an epidemiologist, wife, and mom of two little girls. Hannah Totte, MPH, is an epidemiologist and YLE Community Manager. YLE reaches more than 425,000 people in over 132 countries with one goal: “Translate” the ever-evolving public health science so that people will be well-equipped to make evidence-based decisions. This newsletter is free to everyone, thanks to the generous support of fellow YLE community members. To support the effort, subscribe or upgrade below: Subscribe
Intel Arc Pro B70 Outclasses NVIDIA’s RTX Pro 4000 In AI At Half The Cost, 50% More Memory
Intel's Arc Pro B70 is designed to offer accessible local inference for AI, delivering more memory at half the price of the competition.
Trump Retained Classified Documents Because Of His ‘Business Interests,’ Jack Smith Alleged
Trump allegedly showed a classified map to people aboard his private plane, Smith found during his investigation.
White House says Donald Trump ‘did nothing wrong’ amid reports he showed classified map on plane in 2022
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We disagreed on politics. We agreed on wine. That was enough.
At the Virginia Governor’s Cup Gala in Richmond earlier this month, a very dapper gentleman approached me and introduced himself. In his light-colored suit and bowtie, he looked very Southern in a classical sense, the sort of Virginia Gentleman you used to see south of the Rappahannock as recently as my college days. “I’m a longtime reader and fan of your writing, if not your politics,” he said. His comment was the proverbial iron fist in a velvet glove, simultaneously conveying praise and disapproval while establishing boundaries. Man, I wish we still discoursed like this instead of shouting bromides and insults to try and “own” our opponents with a funny meme and a furrowed brow. Subscribe “Well, we’ll always have wine to share together,” I said, and thanked him for his kind words. We clinked glasses, exchanged pleasantries about the delicious gold medal-winning wines being poured that evening, and went our separate ways. Our exchange reminded me that more unites us than divides us. Wine brings people together to share a meal and a few hours of joy despite our differences.1 That’s why I refer to the wine community — including readers and consumers — rather than the wine industry. Together, we are so much more than production, distribution and sales statistics. A few minutes later the evening’s awards ceremony began. Applause grew as the 12 winemakers who made the top-scoring wines for the Governor’s Case took the stage, including a loud cheer for Jonathan Wheeler of Trump Winery and his 2018 Blanc de Noir sparkling wine. All the winemakers on stage had reason to be proud, Wheeler perhaps more so. Trump Winery was the only winery to win six gold medals in the competition this year. (Wineries are limited to six entries.) Two of Wheeler’s ciders also won gold medals in a separate competition. When you cover the labels and take the sour taste of politics off your palate, the wines are pretty darn good.2 Then Gov. Abigail Spanberger, newly elected Democrat and Virginia’s first female governor, was introduced to great applause to announce which of the 12 wines had won the Governor’s Cup. She spoke for a few minutes about the importance of wine to Virginia’s economy and tourism and the international acclaim Virginia wine has received. Just two weeks earlier, she gave the Democrats’ response to Trump’s State of the Union speech, but this night wasn’t about politics. That didn’t stop several people in the crowd from speculating on the irony should she have to present the trophy to Trump Winery. In the end, Valley Road Vineyards was displayed on the screen behind Spanberger as the winning winery. Blue Bee Cidery in Richmond took top honors for that category. The crowd cheered a female governor presenting the state’s highest trophy to a female winemaker and then resumed the evening’s festivities, united by their mutual love of wine. A whiff of politics couldn’t dim the cheer of celebration and a community united by its love of wine. In Memoriam: Michel Rolland The global wine community lost a giant March 20, with the passing of Michel Rolland. He was 78. Rolland was the original “flying winemaker,” a globe-trotting consultant who helped Bordeaux regain its mojo in the 1970s and then shaped the rise of Napa Valley cult Cabernet as consultant to Simi, Harlan, Newton, Screaming Eagle, Araujo, Dalle Valle and other wineries. He was instrumental in Argentina’s rise to prominence and even had his own winery, Clos de los Siete, in a partnership with other wine families. Rolland’s career arc paralleled that of Robert Parker, the world’s most influential critic. Parker championed many of the wines Rolland consulted on, helping build his reputation and demand for his services. It also made him a target for Parker’s critics. As W. Blake Gray wrote on Wine-Searcher in his excellent tribute to Rolland: Rolland created the type of wines Parker loved: rich body, plenty of fruit, soft tannins. He sometimes faced the accusation of creating a generic international style of red wine, where the great wines he made in Argentina were indistinguishable from the great wines he made in France. Rolland chafed at that critique, as did many of his fans. He was credited with championing green harvesting and leaf pulling, as well as careful selection of grapes in the winery, practices we nearly universally think of today for high-quality winemaking. “Michel was an incredible innovator who changed how wine was made and how grapes were grown,” Napa Valley winemaker Aaron Pott wrote on Facebook. “His work has transformed the wine trade. He created new ways of looking at wine, tasting wine, evaluating ripeness and quality. … This was not just a man with a ‘style’ that he imposed on vineyards but a man that understood how to make great wine from great sites.” Rolland started his consulting company in 1973 in Libourne, in Bordeaux, with his wife, Dany. Both had graduated the year before from Bordeaux’s Institute d’Oenologie. The couple sold their majority share in the business in 2020, according to Wine Spectator. Over his career, Rolland reportedly worked with more than 100 wineries in 20 countries. He even made it to Virginia, where he consulted for Kluge Estate in the mid-2000s. (Kluge Estate is now Trump Winery.) Reader feedback, please! Last week, I did my first WineLine Live! with Dr. Laura Catena of Catena Zapata winery in Argentina. We enjoyed a fascinating discussion about her efforts to preserve the genetic heritage of old vineyards in Mendoza. I conceived of WineLine Live! for paid subscribers, as a thank you for your financial support. And while only a few people joined live, the video now has more views than I have paid subscribers, so I guess that’s pretty good. Even so, I’m considering opening future installments to anyone on Substack to reach a broader audience. So my questions to you: Should these be public? And what format do you prefer? Live gives a chat feature with the potential for viewers to interact with me and the guest, while a video post would just be that. Another alternative is a podcast, which would just be audio, without video of my chins. Please let me know in the comments. Leave a comment In the Glass A few wines I’ve enjoyed recently: Bonny Doon Vineyard Take Me to Your Liter, Le Cigare Volant, Red Wine of the Earth. 2023, Central Coast, CA. Blend of Grenache, Syrah Cinsaut and Petite Sirah. Delightful wine with expressive red fruit flavors, casual drinking. Doon lovers of a certain age will remember Randall Grahm’s Big House Red; this is more in that style than his original Le Cigare Volant, modeled after Chateauneuf du Pape. The liter bottle makes it an even better value. I see this online at about $15. Great value. Albert Bichot Bourgogne Pinot Noir Origines 2023. 13% - Textbook pinot noir and an excellent, affordable entry (regional) Burgundy. Wine Enthusiast Top 100 Wines of 2025. $24 at Total Wine & More. Loma Larga Pinot Noir 2021 “Coastal Cool Climate Wine”, Valle de Casablanca, Chile. An older sample, showing beautifully. Spicy and fruit forward. I’m seeing widely varied pricing online, from $18-$32. At the lower end, it’s a terrific value. 13.5% Dr. Loosen Riesling Dry 2016, Mosel, Germany. Found this “in the stack.” And it stacked up well, shedding some of its youthful acidity for opulent Riesling character, including a hint of the mineral oil older Riesling often features. A great value, as I’m seeing it as low as $14 online. 12% abv. Red Tail Ridge Blau Franc Blend 2024, Sans Oak, Finger Lakes. 13.4% abv. The name is a neat portmanteau of Blaufrankisch and Cabernet Franc, thus Blau Franc. The blend is 50-50, no oak involved. The Blau dominates on the palate, with the spicy caraway seed (think New York deli rye bread). The Franc adds body. The result is juicy, energetic and joyful. Sokol Blosser Estate Rosé of Pinot Noir 2025, Dundee Hills, Willamette Valley, Oregon. This first rosé of 2025 was a welcome respite to our cold, snowy winter here in the Mid-Atlantic. Oh man, I needed this! Bright and energetic, exuberant even, it perks up the mood and goes down fast. 13%. Certified B Corp. Ingredient and nutrition labeling, and in a modest way that doesn’t occupy a lot of label space. (Since it’s not required, presumably there are no minimum font size requirements.) More wineries should follow this example. Dave McIntyre's WineLine is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe Thanks for reading Dave McIntyre's WineLine! This post is public so feel free to share it. Share 1 Some restraint may be required. 2 Especially the bubblies.
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Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
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