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Health Experts Slam Possible FDA ‘Black Box’ Warning for COVID Vaccines

The FDA is reportedly considering the addition of high-level warning labels to COVID vaccines, a move that some experts say may cause unfounded concerns over safety

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Dec 12, 2025 • 12:45 PM EST • Health • scientificamerican.com
Historic preservation group sues over Trump’s White House ballroom plans

The nation’s top historic preservation group said Friday it was suing the Trump administration to block construction of President Trump’s planned 90,000 square-foot ballroom until review boards weigh in on the massive project.

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Dec 12, 2025 • 12:28 PM EST • Politics • cnn.com
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Google Translate now lets you hear real-time translations in your headphones

The real-time headphone translations experience keeps each speaker’s tone, emphasis, and cadence intact, so it’s easier to follow the conversation and tell who’s saying what.

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Dec 12, 2025 • 12:00 PM EST • Technology • techcrunch.com
House GOP leaders race to release health care package Friday

It remains unclear whether members will get to vote on extending the expiring Obamacare subsidies.

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Dec 12, 2025 • 11:34 AM EST • Health • politico.com
Small Business Administration offices in Palisades, Eaton fire zones to close next week

The Small Business Administration is preparing to close its two Los Angeles area offices, but those impacted by the January wildfires can still get help.

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Dec 12, 2025 • 11:20 AM EST • Business • abc7.com
😐 Neutral (14%)
Why affordability is the 'beating heart' of the ACA enhanced subsidy debate, health policy experts say

Health plans proposed by Senate Democrats and Republicans failed on Thursday, making it more likely enhanced ACA subsidies would expire at year end.

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Dec 12, 2025 • 10:17 AM EST • Health • cnbc.com
Who Really Won 2025? The Top-Earning Black Women In Entertainment This Year

From billion-dollar empires to history-making tours, these are the Black women who generated the biggest earnings in entertainment this year.

essence.com logo
Dec 12, 2025 • 10:00 AM EST • Entertainment • essence.com
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50 Cent to get $50 million from the state for Shreveport projects. There are clawbacks.

Curtis "50 Cent" Jackson gets big state support for Shreveport plans.

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Dec 12, 2025 • 9:45 AM EST • Business • shreveportbossieradvocate.com
Netflix, Warner, Paramount and antitrust: Entertainment megadeal’s outcome must follow the evidence, not politics or fear of integration

Even President Trump is concerned about this situation. But the answers aren’t obvious.

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Dec 12, 2025 • 8:05 AM EST • Entertainment • fortune.com
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Netflix, Warner, Paramount and antitrust: Entertainment megadeal’s outcome must follow the evidence, not politics or fear of integration

Even President Trump is concerned about this situation. But the answers aren’t obvious.

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Dec 12, 2025 • 8:05 AM EST • Politics • fortune.com
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The Pluribus apocalypse gets a little quieter

Spoilers ahead.

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Dec 12, 2025 • 8:00 AM EST • Entertainment • theverge.com
‘Pig butchering’ cryptocurrency scam cheats Minnesota business owner out of $500K

The scam’s target went to law enforcement after being asked for another $240,000, according to a court filing.

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Dec 12, 2025 • 8:00 AM EST • Business • startribune.com
Kirby Air Riders team is disbanding soon, but game could get another balance patch

According to director Masahiro Sakurai, the team behind Kirby Air Riders will be disbanding soon. At this point there largely isn’t a reason to keep everyone together. Development is finished, and as previously announced, the game isn’t getting DLC. However, we’re likely to get one more balance patch. Sakurai shared the following on social media: “As discussed in Air Riders...

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Dec 12, 2025 • 7:49 AM EST • Technology • nintendoeverything.com
Broadcom's AI Business Is Growing Fast. Here's Why the Stock Is Tanking Anyway.

Broadcom on Thursday said its AI revenue will double in the current quarter, but shares slumped as investors focused on narrowing margins after a major run-up in the stock price.

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Dec 12, 2025 • 7:00 AM EST • Business • investopedia.com
Why did it take Eagles so long to get Britain Covey involved in return game?

Watching Britain Covey return punts and kicks Monday night against the Chargers it was easy to wonder why he hasn’t been doing it all year.

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Dec 12, 2025 • 7:00 AM EST • Sports • nbcsportsphiladelphia.com
3 theories that explain Trump’s collapsing support

How Trump’s winning coalition is unraveling in real time.

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Dec 12, 2025 • 6:45 AM EST • Politics • vox.com
The OnePlus 15R is about to get a version we didn’t expect

The Electric Purple 15R Ace Edition, previously China-only, could reach global buyers.

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Dec 12, 2025 • 6:13 AM EST • Technology • phonearena.com
Wisconsin candidates decry money in politics, promise to raise a ton of it

Wisconsin is among the worst states in the union for high-dollar elections and loose regulations of campaign cash

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Dec 12, 2025 • 6:00 AM EST • Politics • wisconsinexaminer.com
The top 10 gadgets of 2025

A tiny sunlight emulator, a video player for your dreams and a vest for listening to trees feature in this roundup of our favourite gadgets.

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Dec 12, 2025 • 6:00 AM EST • Technology • dezeen.com
Republicans and Democrats can work together on healthcare, says Trump, as rise in premiums looms

President spoke at Congressional ball after Senate rejected two competing proposals to address imminent expiration of Obamacare subsidies

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Dec 12, 2025 • 5:39 AM EST • Politics • theguardian.com
Which blockbuster movies defined 2025's year in film?

A year of daring originals and audience-favorite franchises top the list of 2025's most memorable films of the year.

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Dec 12, 2025 • 5:10 AM EST • Entertainment • usatoday.com
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FDA intends to put its most serious warning on Covid vaccines, sources say

The US Food and Drug Administration intends to put a “black box” warning on Covid-19 vaccines, according to two people familiar with the agency’s plans.

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Dec 12, 2025 • 5:00 AM EST • Health • cnn.com
Sticker Shock: Obamacare Customers Confront Premium Spikes as Congress Dithers

With subsidies that give consumers extra help paying their health insurance premiums set to expire, lawmakers are again debating the Affordable Care Act. The difference this time: It’s happening in the middle of ACA open enrollment.

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Dec 12, 2025 • 5:00 AM EST • Health • kffhealthnews.org
Laughing about science more important than ever: Ig Nobel founder

With science increasingly coming under attack, using humor as a way to get people interested in scientific research is more important than ever, the founder of the satirical Ig Nobel prizes said.

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Dec 12, 2025 • 4:30 AM EST • Science • phys.org
Rachel Reeves to blame for economy shrinking before budget, Tories claim

Shadow chancellor says unexpected contraction is ‘direct result of Labour’s economic mismanagement’

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Dec 12, 2025 • 4:08 AM EST • Politics • theguardian.com
Past Ulster disappointments driving Kilcoo

With 13 Down titles over the past 14 years, one may get the impression that success can be taken for granted in Kilcoo, but current manager Martin Corey insists there is a sense they "have left a lot behind them" beyond their county boundary.

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Dec 12, 2025 • 3:10 AM EST • Sports • bbc.com
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Thailand dissolves parliament, heightening political turmoil as Trump seeks to salvage ceasefire with Cambodia

The escalation broke the ceasefire brokered in July by Trump who threatened to halt trade talks with the two countries unless they ended the fight.

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Dec 12, 2025 • 1:11 AM EST • Politics • cnbc.com
UK GDP report to show if economy struggled in October before the budget

Rolling coverage of the latest economic and financial news

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Dec 12, 2025 • 1:07 AM EST • Business • theguardian.com
😐 Neutral (15%)
Theater Review: "Stereophonic" Tour Offers Sharp Music, Uneven Storytelling

Kevin Taft reviews the theatrical production of the Tony-nominated Stereophonic, which he nevertheless feels never comes together in a dramatically satisfying way.

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Dec 12, 2025 • 12:33 AM EST • Entertainment • weliveentertainment.com
‘You won’t understand unless you chew on it’: Hideo Kojima wants you to remember his games for decades

With narrative storytelling, multimillion-dollar budgets and A-list casts, Hideo Kojima’s arthouse games — including the critically acclaimed “Metal Gear Solid” and “Death Stranding” franchises — are as cinematic as, well, cinema.

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Dec 12, 2025 • 12:02 AM EST • Technology • cnn.com
Falcons vs. Buccaneers: Tampa loses playoff footing after getting stunned by monster games from Kirk Cousins and Kyle Pitts in 29-28 defeat

If the Buccaneers miss the playoffs, they’ll wonder how Cousins knocked them out of a division title.

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Dec 11, 2025 • 11:43 PM EST • Sports • sports.yahoo.com
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Trump targets Indiana GOP Senate leader after defeat of redistricting plan

President Trump said he hopes the top Republican in the Indiana state Senate loses his next primary after Indiana rejected a redistricting plan.

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Dec 11, 2025 • 9:56 PM EST • Politics • usatoday.com
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Get Ready to Ride the Light: Diablo 4's Next Expansion Adds Paladin Class, Revamps the Endgame

A second new class will also be included in the expansion, which focuses on the fight against Mephisto.

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Dec 11, 2025 • 9:50 PM EST • Technology • cnet.com
NFL Week 15 predictions: Our experts pick Packers vs. Broncos and more top games

Here are our best bets for Packers vs. Broncos, Chargers vs. Chiefs and more NFL Week 15 games.

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Dec 11, 2025 • 8:30 PM EST • Sports • cbssports.com
Michael Jordan was already a basketball legend. Now, he’s one in NASCAR too

Thursday's settlement was that significant for NASCAR's teams that Jordan just made himself a transformative figure in yet another sport.

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Dec 11, 2025 • 7:37 PM EST • Sports • nytimes.com
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Google asks UK experts to find uses for its powerful quantum tech

UK researchers will get a chance to develop applications for the tech giant's quantum processor.

bbc.com logo
Dec 11, 2025 • 7:34 PM EST • Technology • bbc.com
Google launched its deepest AI research agent yet — on the same day OpenAI dropped GPT-5.2

For the first time, developers can embed Google's Deep Research tool, based on Gemini 3 Pro, into their own apps.

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Dec 11, 2025 • 7:18 PM EST • Technology • techcrunch.com
Science Shouldn’t Rely on Corporate Software (opinion)

We need to treat the software undergirding scientific research as a public good—and make investments accordingly.

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Dec 11, 2025 • 7:00 PM EST • Science • insidehighered.com
Analysis: How the White House is using misleading comparisons to make inflation sound better

The year-over-year inflation rate in January, the month President Donald Trump returned to the White House, was 3.0%.

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Dec 11, 2025 • 6:13 PM EST • Politics • cnn.com
Long: As NASCAR antitrust lawsuit reaches settlement, a win for fans who get their sport back

23XI Racing co-owner Michael Jordan credited "level heads" in reaching an agreement.

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Dec 11, 2025 • 5:48 PM EST • Sports • nbcsports.com
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Michigan AD became aware of Sherrone Moore's recent mental health issues before firing, source says
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Dec 11, 2025 • 5:44 PM EST • Health • cbsnews.com
High-Signal Publisher
'We're not just going to want to be fed AI slop for 16 hours a day': Analyst sees Disney/OpenAI deal as a dividing line in entertainment history

"​I think the reason this bidding is approaching $100 billion-plus is the content library and the potential to do a Disney-OpenAI type of deal."

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Dec 11, 2025 • 5:36 PM EST • Entertainment • fortune.com
Indiana Republicans block new congressional map in rare break with Trump

Indiana's Republican-led senate voted against a redrawn congressional map Thursday that would have favored their party in the 2026 elections, despite months of pressure by President Donald Trump for a rare mid-cycle redistricting.

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Dec 11, 2025 • 5:34 PM EST • Politics • pbs.org
🙂 Positive (35%)
Hochul signs several bills into law on artificial intelligence regulations

One piece of legislation aims to stop artificial intelligence from being used to essentially recreate people who have died.

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Dec 11, 2025 • 5:26 PM EST • Politics • spectrumlocalnews.com
RFK Jr.’s Health Department Is Pondering a National Men’s Health Initiative

At an FDA discussion of testosterone replacement therapy, a top official called for special health centers to address a “men’s health crisis.” Others called to ease men’s access to hormones.

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Dec 11, 2025 • 5:11 PM EST • Health • wired.com
In a setback for Trump, Indiana lawmakers defeat redistricting plan

Republicans resisted the call by President Trump for redistricting. He and the state's Republican governor threatened to back primary challenges against Senators who wouldn't get on board.

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Dec 11, 2025 • 4:48 PM EST • Politics • npr.org
High-Signal Publisher
Indiana Senate Republicans reject Trump’s redistricting push

The Indiana Senate on Thursday voted down a plan to redraw the state’s congressional districts to hand Republicans two more seats, dealing President Donald Trump a rare rebuke from his own party in the face of the president’s months-long campaign to pressure the GOP supermajority in the deep-red state to bend to his will.

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Dec 11, 2025 • 4:37 PM EST • Politics • cnn.com
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Evommune Reports Third Quarter 2025 Financial Results and Provides Business Update

PALO ALTO, Calif., December 11, 2025--Evommune, Inc. (NYSE: EVMN) (the "Company"), a clinical-stage biotechnology company developing innovative therapies that target key drivers of chronic inflammatory diseases, today announced financial results for the third quarter ended September 30, 2025, and provided a business update.

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Dec 11, 2025 • 4:05 PM EST • Business • finance.yahoo.com
How Investors May Respond To Elevance Health (ELV) Expanding AI Assistant Access And Adding Schulman To Board

Elevance Health recently expanded access to its AI-powered Virtual Assistant for about 22 million commercial members and announced that Amy Schulman, a senior healthcare executive and governance expert, will join its board and sit on the Audit and Finance Committees in January 2026. Together, these moves highlight Elevance Health’s push to blend digital-first member support with strengthened board oversight in healthcare innovation and regulatory strategy. We’ll now examine how the broader...

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Dec 11, 2025 • 3:08 PM EST • Health • finance.yahoo.com
Justice Department fails to reindict Letitia James for a second time

A grand jury, for a second time, declined to bring a new indictment against Letitia James, the New York attorney general who defeated President Donald Trump and his company in court, according to multiple sources.

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Dec 11, 2025 • 3:08 PM EST • Politics • cnn.com
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Menopause treatment is getting personal

Menopause care innovations include at-home hormone testing, virtual appointments, and new non-hormonal therapies for symptom relief.

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Dec 11, 2025 • 2:51 PM EST • Business • businessinsider.com
🙂 Positive (50%)
After a year of Trump-inspired inaction, some Republicans in Congress are growing restless

A year after President Donald Trump’s election and with next year’s midterms looming, congressional deference to the White House is showing signs of wearing on some Republicans.

cnn.com logo
Dec 11, 2025 • 1:38 PM EST • Politics • cnn.com
Ars Live: 3 former CDC leaders detail impacts of RFK Jr.’s anti-science agenda

Join us Tuesday, December 16, at 2 pm ET to hear from leaders who resigned in protest.

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Dec 11, 2025 • 1:33 PM EST • Science • arstechnica.com
Blame Republicans for our health insurance mess

Conservatives haven’t taken health policy seriously for decades.

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Dec 11, 2025 • 1:30 PM EST • Health • vox.com
Navy delivers report to Hegseth on potential punishment for Sen. Mark Kelly over ‘illegal orders’ video

The US Navy has submitted its recommendations on potential punishments for Democratic Sen. Mark Kelly over his participation in a video that reminded US troops they have a duty to refuse illegal orders, a Pentagon official told CNN on Thursday.

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Dec 11, 2025 • 1:20 PM EST • Politics • cnn.com
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Some lawmakers see path for health care compromise after failed Senate votes
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Dec 11, 2025 • 1:17 PM EST • Health • cbsnews.com
High-Signal Publisher
MLB rumors: Tarik Skubal trade talks continue, Braves sign reliever Robert Suarez

Here are your hot stove rumors for Thursday, Dec. 11

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Dec 11, 2025 • 1:08 PM EST • Sports • cbssports.com
Disney CEO Bob Iger Says OpenAI Deal Gives Entertainment Giant 'A Way In' to AI

The Walt Disney Company and OpenAI announced a deal Thursday that will make Disney characters available through the ChatGPT maker's image and video generation tools, and see Disney invest $1 billion in OpenAI.

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Dec 11, 2025 • 1:03 PM EST • Entertainment • investopedia.com
Google debuts 'Disco,' a Gemini-powered tool for making web apps from browser tabs

Google Labs is testing a product that will work with your browser tabs to make web apps for you.

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Dec 11, 2025 • 1:00 PM EST • Technology • techcrunch.com
Trump takes steps toward demolishing four federal buildings, preservationist alleges

After demolishing the White House’s East Wing, President Donald Trump is now eying four federal buildings for the same treatment and is circumventing a key government agency with his plans, according to a historic preservationist raising the alarm.

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Dec 11, 2025 • 12:21 PM EST • Politics • cnn.com
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Elon Musk calls DOGE ‘only somewhat successful,’ rules out return
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Dec 11, 2025 • 12:01 PM EST • Politics • cnn.com
Southwest Airlines eyes airport lounges business

For Southwest, having lounges would attract business and frequent flyer customers, who have grown accustomed to the perk at other carriers

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Dec 11, 2025 • 11:54 AM EST • Business • qz.com
FMOL Health has purchased this property near Our Lady of the Lake

FMOL Health has acquired a kidney care facility property on Flanders Drive near Essen Lane. The system purchased the site through Our Lady of the Lake Hospital Inc. from Flanders Building LLC f… Already an INSIDER? Sign in. We are glad you enjoy reading Business Report. Continue reading this story and get ACCESS to all […]

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Dec 11, 2025 • 11:00 AM EST • Health • businessreport.com
'Heated Rivalry' stars talk overnight success, butt tweets, and viral moments

'Heated Rivalry's Connor Storrie and Hudson Williams are still processing those fans tweeting about their butts. The actors get into the spicy drama's runaway success and go behind the scenes of viral moments.

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Dec 11, 2025 • 11:00 AM EST • Entertainment • ew.com
CNBC Sport: Utah breaks the private equity seal with historic $500 million investment

Utah may have designed a template for other schools to bring in private capital to help fund their athletic programs.

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Dec 11, 2025 • 10:15 AM EST • Sports • cnbc.com
Walton family fortune: How American's richest family manages their wealth

America's richest family uses a model pioneered by the Rockefellers to manage their wealth.

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Dec 11, 2025 • 9:30 AM EST • Business • cnbc.com
I'm a millennial tech nerd. Here are 15 geeky gifts and gadgets I'd buy for myself!

'Tis the season to get the perfect gift. It could be for your nerdy self or even your geeky friends. I have ideas.

pcworld.com logo
Dec 11, 2025 • 9:13 AM EST • Technology • pcworld.com
Senate live updates as health care bills come up for votes with price hikes on the horizon
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Dec 11, 2025 • 9:11 AM EST • Health • cbsnews.com
High-Signal Publisher
HR's big challenge with AI will force HR people to reinvent themselves

Workers fear AI, so one of HR's biggest challenges is getting workers to trust and adopt it by building credibility and addressing employee concerns.

businessinsider.com logo
Dec 11, 2025 • 9:08 AM EST • Business • businessinsider.com
Live updates: Trump administration, health care vote and latest Venezuela news
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Dec 11, 2025 • 8:19 AM EST • Health • cnn.com
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Live updates: Trump administration, health care vote and latest Venezuela news
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Dec 11, 2025 • 8:19 AM EST • Politics • cnn.com
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Trump’s affordability argument just got the unlikeliest champion

The main reason Americans are upset about the economy: They are still adjusting to high prices that surged during years of runaway inflation that took place during former President Joe Biden’s term.

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Dec 11, 2025 • 8:00 AM EST • Business • cnn.com
Capitol agenda: GOP’s health revolt heads to the Senate

John Thune and Mike Johnson can’t get Republicans on the same page on health care.

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Dec 11, 2025 • 8:00 AM EST • Health • politico.com
IRS releases health savings account expansion details under Trump's 'big beautiful bill'

IRS releases health savings account expansion details under President Donald Trump's "big beautiful bill." What it means for ACA health plan enrollees.

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Dec 11, 2025 • 7:35 AM EST • Health • cnbc.com
Senate to vote on 2 health care proposals. And, the latest U.S. move against Venezuela

The Senate is expected to vote on two opposing health care proposals today. And, the Trump administration says it has seized an oil tanker off the coast of Venezuela in its latest move in the region.

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Dec 11, 2025 • 7:14 AM EST • Health • npr.org
Deep dive High-Signal Publisher
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Analysis: The Civil Rights law that Stephen Miller says ruined America

Trump’s key aide thinks the country was better off with strict quotas that sought to preserve the racial makeup of the country in the 1920s and so favored immigrants from Western and Northern Europe over what he called “third world countries.”

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Dec 11, 2025 • 6:01 AM EST • Politics • cnn.com
Commentary: The U.S. Senate is a mess. He wants to fix it, from the inside

Oregon Sen. Jeff Merkeley is waging a largely one-man crusade to reform the Senate filibuster. He sees it as a way to help end obstructionism and address the Senate's increasing dysfunction.

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Dec 11, 2025 • 6:00 AM EST • Politics • latimes.com
Business leaders make their 2026 predictions for the Magnificent 7

'I’d rather be in Jensen’s seat than anywhere else'

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Dec 11, 2025 • 5:58 AM EST • Business • fortune.com
Braid and The Witness Creator Jonathan Blow Teases The Game Awards Announcement

Jonathan Blow has just "announced an announcement," teasing he just may be getting on a plane today to join a "gaming industry event coming up." All roads lead to The Game Awards!

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Dec 11, 2025 • 5:46 AM EST • Technology • ign.com
Monster Hunter Wilds finally gets PC optimisation roadmap to coincide with Title Update 4, but players still aren't really happy

"They’re even drip feeding optimization lmao," says one player.

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Dec 11, 2025 • 5:37 AM EST • Technology • eurogamer.net
Republicans worry Trump is missing the mark on affordability

President Donald Trump’s high-profile economic speech on Tuesday night was meant to alleviate Americans’ concerns about the cost of living. Instead, it mainly appeared to deepen fears within the GOP that he’s not quite getting it.

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Dec 11, 2025 • 5:00 AM EST • Politics • cnn.com
Senate to vote on dueling health care proposals as ACA premium hikes loom

The Senate is set to vote on dueling health care proposals. Both plans are likely to fail, even as Affordable Care Act premiums are set to skyrocket at the end of the year.

npr.org logo
Dec 11, 2025 • 5:00 AM EST • Health • npr.org
High-Signal Publisher
Health insurers ask GOP to fix their fraud problem — and extend Obamacare subsidies

In a last-minute plea, insurers are urging Republicans to crack down on fraud in their industry.

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Dec 11, 2025 • 4:45 AM EST • Health • politico.com
Tiny tracker following monarch butterflies during California migration

When this monarch butterfly hits the sky it won't be traveling alone. In fact, an energetic team of researchers will be following along with a revolutionary technology that's already unlocking secrets that could help the entire species survive.

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Dec 11, 2025 • 1:16 AM EST • Science • abc7news.com
😐 Neutral (14%)
A divided GOP forges ahead on health care message — without plan to address spiking premiums

Congressional Republicans are taking a major political gamble this week, laying out a GOP health care agenda that ignores the soon-to-expire enhanced subsidies that help tens of millions of Americans afford Obamacare — despite pleas from some in their own party.

cnn.com logo
Dec 11, 2025 • 12:02 AM EST • Health • cnn.com
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A divided GOP forges ahead on health care message — without plan to address spiking premiums

Congressional Republicans are taking a major political gamble this week, laying out a GOP health care agenda that ignores the soon-to-expire enhanced subsidies that help tens of millions of Americans afford Obamacare — despite pleas from some in their own party.

cnn.com logo
Dec 11, 2025 • 12:02 AM EST • Politics • cnn.com
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The New WHO Pandemic Treaty and Global Health Governance: Incorporating Common but Differentiated Responsibilities into PABS  - Georgetown Journal of International Affairs

On May 20, 2025, the World Health Assembly unanimously adopted the World Health Organization (WHO) Pandemic Agreement, an international treaty designed to strengthen pandemic prevention, preparedness, and response. The product of three years of arduous negotiations, the treaty marks a new era of global cooperation in public health. However, core aspects of the agreement remain unresolved—notably the Pathogen Access and Benefit-Sharing (PABS) System, which is intended to ensure equitable access to pandemic-related materials and benefits. To support the successful implementation of the WHO Pandemic Agreement, the principle of “common but differentiated responsibilities” should be formally incorporated into the negotiating agenda of the PABS annex. Introduction For the first time, an international treaty has enshrined the principle of “One Health,” the compelling idea that the health of animals, humans, and the environment all contribute to pandemic risks. SARS (2003), H1N1 (2009–10), Ebola (2014–16), and COVID-19 all emerged through zoonotic spillover from animal hosts—respectively, civets, hogs, and bats. Together, they underscore the need for a coordinated, cross-sectoral approach. The Pandemic Agreement responds to this call, requiring state parties to acknowledge the ecological interplay and commit to a comprehensive “One Health” strategy. Specifically, Article 5 charges governments to address “the drivers of pandemics and the emergence and re-emergence of infectious disease at the human-animal-environment interface,” including wild animal markets, deforestation, and antibiotic overuse. Yet the effectiveness of this “One Health” vision depends equally on the free flow of scientific information and data among countries and institutions. Just as environmental and animal health factors have been neglected in past global frameworks, so too has data sharing been marginalized, despite its centrality to timely detection and response. The Pandemic Agreement takes an important step by requiring governments to enhance data collection and cooperate with the World Health Organization (WHO). However, these provisions will remain aspirational without a robust Pathogen Access and Benefit-Sharing (PABS) annex. The PABS system will determine whether countries and researchers can rapidly exchange pathogen samples and genetic data while ensuring equitable access to resulting research and development, including diagnostics, therapeutics, and vaccines. Without such mechanisms, the treaty’s promise to operationalize “One Health” and strengthen global preparedness will risk becoming largely symbolic, echoing earlier failures to translate shared principles into coordinated action. Equity Concerns When the 2025 Health Assembly adopted the Pandemic Agreement, it left the difficult question of access to pathogens and the sharing of resulting benefits to be addressed in a separate agreement. Negotiations on this separate agreement, PABS, are now underway in Geneva. Yet governments remain divided over fundamental questions of equity between the countries that primarily contribute to the system and those that primarily draw from it—and consequently benefit. For example, wildlife in countries bordering the equator is likely to produce PABS materials, but companies in Europe are likely to use them to develop lucrative products. The most likely contributor countries are likely to be those biodiverse countries around the equator, such as Brazil, the Democratic Republic of the Congo, and Indonesia, where the number of human-mammalian viral host interactions is large. Conversely, countries most likely to benefit from this material are those with the technology, investors, and infrastructure to capitalize on genomic data, such as the United States, EU member states, and Japan. This imbalance reflects a broader pattern seen in prior international frameworks. Now, as in the past, the wealthiest countries in the world (a useful heuristic is membership of the Organisation for Economic Co-operation and Development (OECD)) disproportionately benefit from systems in which pathogens and genomic sequencing data are contributed to a common source. Under the International Agreement on Plant Genetic Resources for Food and Agriculture (the “Plant Treaty” or “Seed Treaty”) and the Pandemic Influenza Preparedness (PIP) Framework, companies from Europe and North America disproportionately withdraw biological samples and data for development into lucrative medical products. Their governments and companies have both statutory and contractual claims to the products that those companies correspondingly produce. PABS appears poised to follow the same pattern. The text calls for strong language on access to pathogens and associated data, but the corresponding benefits that should flow to poorer countries are couched in equivocal or non-binding language. Common but Differentiated Responsibilities To address these inequities, the principle of “common but differentiated responsibilities” should be formally incorporated into the negotiating agenda of the PABS annex. Common but differentiated responsibilities are often a feature of climate change negotiations. The basic principle is that, even though all countries should reduce carbon emissions, governments that became rich and powerful through massive carbon emissions (e.g., France, the United Kingdom, the United States) should have a greater obligation to address the resulting crises. Applied to PABS, it would require that governments hosting and supporting companies developing lucrative products carry greater obligations toward the cost of running the PABS system; share benefits or final medical products; and transfer technology to help countries worldwide develop their own capacities to innovate and manufacture vaccines during an emergency. For example, an annex could mandate that any company based in an OECD country that withdraws PABS material would be obligated to donate the resulting diagnostics, therapeutics, or vaccines to the WHO during a public health emergency or pandemic. Questions remain about how robust those donations would be, but the principle is that they should deliver highly significant lifesaving benefits to be equitably shared. Theoretically, this approach mirrors the PIP Framework, in which companies withdrawing influenza samples are required to pay half of the operating costs. In practice, however, the framework has fallen short. The PIP Framework Secretariat has struggled to secure payments from companies, with companies often disagreeing over how much is owed. Additionally, without another pandemic influenza to test the strength of the agreement during a public health emergency, corporate compliance with sharing mechanisms remains unknown. Even if these limitations did not characterize the PIP Framework, partially paying for operating expenses does not address the inequity in access to genetic data and pathogen samples that left less developed countries last in line for COVID-19 vaccines (and, before them, H1N1). Common but differentiated responsibilities would go further, addressing governments’ legitimate grievances regarding information sharing. It would make withdrawals of PABS material and resulting products more transparent, building trust across the board. Enforcement and Enduring Success A key implication of this approach is that the governing mechanism of the PABS must have real enforcement authority. The WHO Pandemic Agreement delegates its core governance responsibilities to a Conference of the Parties (COP)—a governing body composed of one representative from each participating government, similar to those established under the UN Framework Convention on Climate Change and the WHO Framework Convention on Tobacco Control. The proposed WHO Pandemic Agreement COP is charged with oversight functions but ultimately possesses no real authority to compel a government to take any action it does not wish to take. The text does not give the COP the ability to, for example, sanction a party that does not comply with either textual obligations or PABS provisions. In other words, there are no effective mechanisms in place to ensure compliance. Perhaps just as significant, establishing a meaningful enforcement mechanism within the PABS system would strengthen the WHO’s credibility and its ability to ensure compliance across global health governance. By setting a precedent for accountability, such a mechanism could enhance the organization’s authority not only within the Pandemic Agreement but also in enforcing the revised International Health Regulations and other frameworks for public health emergencies. Conclusion The PABS annex can—and should—be different. It should establish clear responsibilities for funding as well as for sharing the diagnostics, therapeutics, and vaccines that result from contributions to the system. The system, in turn, must include a dedicated body empowered to hold governments and the corporations they sponsor accountable for their responsibilities before, during, and after pandemics. Doing so would restore trust in the broader agreement, which was eroded as commitments were repeatedly diluted while parties scrambled to meet their own self-imposed deadlines during the Pandemic Agreement negotiations. A robust PABS Annex would cement a grand social bargain. Wealthier countries and their corporations would gain unimpeded access to scientific information essential for developing and manufacturing lifesaving medical products. As such, they would stand to gain considerable economic benefit. Yet that privilege must be matched with responsibility. The grand bargain must include not only the right to innovate, but also the duty to ensure that innovation serves all. As medical products are developed and produced through collective contributions, every person must have equal access. All human beings deserve an equitable chance to survive—to save their own life, the lives of their families, and the well-being of their communities. … Sam Halabi, JD, MPhil, is the Bette Jacobs Endowed Professor at Georgetown University’s School of Health and the Director of the Center for Transformational Health Law at Georgetown Law. He serves as the co-lead for the WHO’s Working Group on Regulatory Consideration on AI and Health’s training workstream. He earned his JD from Harvard, his MPhil from Oxford, and undergraduate degrees from Kansas State University. Lawrence Gostin, LLD (Hon.), JD, BA, is University Distinguished Professor and Founding Director and Timothy and Linda O’Neill Professor of the O’Neill Institute for National and Global Health Law. He is the author of Global Health Security: A Blueprint for the Future (Harvard University Press, 2021); Global Health Law (Harvard University Press, 2014); Public Health Law: Power, Duty, Restraint (University of California Press, 3rd ed., 2016); Public Health Law and Ethics: A Reader (University of California Press, 3rd ed., 2018); Law and the Health System (Foundation Press, 2014); Principles of Mental Health Law & Practice (Oxford University Press, 2010). He also directs the WHO Collaborating Center at Georgetown University. Image Credit: United States Mission Geneva, CC BY 2.0, via Wikimedia Commons

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Dec 11, 2025 • 12:00 AM EST • Health • gjia.georgetown.edu
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