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NMU Sports Hall of Fame Tickets on sale
MARQUETTE, Mich. – Tickets for the 2026 Northern Michigan University Sports Hall of Fame Banquet are now on sale and will remain available through Friday, Sept. 11.
What do fans think of potential minority share sale?
Liverpool fans consider the club to have a specific set of values, centred around its working-class roots. When FSG attempted to raise season ticket prices last season, fans' group Spirit of Shankly (SOS) launched a campaign called 'Not a Pound in the Ground'. It urged fans to buy food and drink from local businesses in the Anfield area rather than inside the stadium.
Who are TNT Sports' presenters, commentators and pundits for the UEFA Super Cup?
TNT Sports will bring coverage live from Salzburg as Aston Villa go head-to-head with Paris Saint-Germain
ARMK Q2 Deep Dive: Nexus Expansion and Core Business Growth Drive Momentum
Food and facilities services provider Aramark (NYSE:ARMK) reported revenue ahead of Wall Street’s expectations in Q2 CY2026, with sales up 9.3% year on year ...
Jacobs Entertainment now wants two skyways (commentary)
A proposal for new skyways from J Resort faces review by the Reno Planning Commission and City Council following its debut at the Ward 1 NAB meeting.
Desmond Bane Wants College Basketball to Add a Salary Cap
Bane is TCU’s chief basketball officer.
Kidpreneurs mean business
UND-hosted Kidpreneur Program gives Grand Forks students hands-on experience with branding, pricing, sales and entrepreneurship
Rare Mario Brothers cartridges being auctioned off for sale after unique find in Wisconsin
A set of unique, extremely rare Super Mario cartridges was found in a gaming store in Waukesha, Wisconsin, and will be auctioned off starting Friday.
AI Could Help Researchers Get Funding—But at What Cost?
Scientists who use AI to draft research proposals are earning more money, but their ideas may be less likely to move the field forward.
Alkami Puts Digital Banking Business up for Sale
Digital banking software firm Alkami Technology has reportedly put itself up for sale. The move came after the company saw interest from potential buyers
Bitget Expands CFD Business with Institutional-Grade Liquidity Solutions
VICTORIA, Seychelles, Aug. 11, 2026 (GLOBE NEWSWIRE) -- Bitget, the world's largest Universal Exchange (UEX), has expanded its CFD business with...
Dem governor booed at Virginia Old Fiddlers' Convention
Video shows Virginia Democratic Gov. Abigail Spanberger greeted by loud boos at the Old Fiddlers' Convention in Galax amid sagging poll numbers.
US existing home sales post second straight monthly decline in July
U.S. existing home sales fell for a second straight month in July, and a rebound is likely to be limited by higher mortgage rates and tight supply.
LG Launches Back to School Sale With Major Discounts on OLED TVs and Monitors
LG is hosting a big Back to School sale on its website this week, with deals on monitors, TVs, home appliances, and more. LG's discounts have been automatically applied and do not require any discount codes or special memberships. Note: MacRumors is an affiliate partner with LG. When you click a link and make a purchase, we may receive a small payment, which helps us keep the site running.
A RAPID proposal for breakthrough coverage, and nurses push back on AI
In this edition of STAT Health Tech: Details from CMS and FDA on the RAPID pathway for breakthrough devices, and nurses push back on AI.
America Already Built the World's Largest Science-Vetting Machine | The Foundation for American Innovation
Every year, federal agencies assess over a hundred thousand proposals that they never fund. Treating those peer review as public infrastructure could help unlock much more philanthropic capital for American research.
GTA 6 might not cost $100, but most of the people pre-ordering it are buying it at that price, Take-Two reveals
Rockstar put a lot of effort into enticing people into pre-ordering the more expensive Ultimate edition.
The U.S. Healthcare System is Already Mostly Socialized
Now that Abdul El-Sayed is the Democratic nominee for Michigan’s open Senate seat, the outcome of this crucial race will depend mainly on two things: Whether Republicans succeed in demonizing El-Sayed because he’s brown and a Muslim, and whether they succeed in demonizing him as a left-wing radical. I will defer for the now the question of whether bigotry will be effective this year, although I will address it another day. What I want to address instead is El-Sayed’s signature issue — healthcare. Yes, El-Sayed advocates Medicare for All, a position the usual suspects denounce as “socialism.” I will get to the politics of his stance soon. Today, however, I want to talk about the substance. We should be clear that El-Sayed doesn’t even call himself a socialist. On the contrary, he explicitly disavows the label, saying “I’m a capitalist who just knows about capitalism”. In fact, as I explained in a previous post, the policies that El-Sayed advocates qualify him as a social democrat, not a socialist. Still, El-Sayed advocates a system under which the government would pay almost all medical expenses. Isn’t that socialism? Well, if that is the criterion then much of U.S. healthcare is already socialist. In fact, the government’s role is so large that U.S. healthcare is better described as partially privatized socialism than as anything resembling a free market. Let’s start with the raw numbers on health insurance, which pays the bulk of Americans’ medical expenses. Americans receive health insurance either from private companies or from public programs, overwhelmingly Medicare and Medicaid. Here’s what the breakdown of coverage and spending between private and public looked like in 2024: While a majority of Americans with health insurance get it from private companies, well over 100 million of us are covered by government programs instead. And these government programs pay more total dollars for medical bills than the private insurers do. Why do government programs that cover a minority of the population account for a majority of health insurers’ outlays? Mainly because Medicare covers seniors, and we’re expensive. Also, while Medicaid covers many younger Americans, disabled and elderly beneficiaries account for most of its spending. Even by the raw numbers, then, U.S. health insurance looks as much public as private. But that understates the government’s role: Private health insurance in the U.S. is both highly regulated and heavily subsidized. This is obviously true for the insurance coverage purchased by tens of millions of Americans through the exchanges established by the Affordable Care Act. But employment-based health insurance, which covers 161 million Americans, is far more of a government creation than most people realize. For employment-based insurance exists largely because of huge implicit government subsidies that come with major strings attached. Here’s how that works. If your employer pays you $10,000, that’s taxable income. But if your employer pays $10,000 toward a company health insurance plan that meets certain criteria, it isn’t taxable. That’s a huge effective subsidy, running at more than $300 billion a year. Take that subsidy into account, along with the more than $100 billion per year spent subsidizing policies purchased under the ACA, as well as the outlays on Medicare and Medicaid, and net effect is that the government pays for more than two-thirds of Americans’ health insurance. Granted, there are strings attached. Roughly speaking, employment-based health plans can’t discriminate based on medical history — that is, they can’t deny coverage to employees with pre-existing conditions — and they also can’t offer the plans only to highly compensated employees — a health plan that is only for the C-suite is considered taxable income. So given the restrictions of the federal tax code, employer-based health insurance is a lot like Obamacare, which also prohibits discrimination based on medical history and provides subsidies to make insurance affordable to lower-paid workers. The fact is that virtually all of private healthcare insurance is already well under some form of government control through regulation and tax subsidies. How should we think about this system? First of all, is Medicare socialist? Don’t tell anyone, but the way Medicare operates — it covers every senior’s medical expenses, whatever they turn out to be, while being funded by taxes that depend on one’s income — could be summarized by the old Marxist slogan “From each according to his ability, to each according to his need.” And back in 1961, when Ronald Reagan was the face of a last-ditch effort by the American Medical Association to block the creation of Medicare, he denounced Medicare as “socialized medicine” and warned that it would destroy our freedom. In reality, American freedom survived until Jan. 20, 2025, while Medicare is immensely popular, with an 82 percent favorable rating in the most recent KFF survey. Medicaid, government health insurance for lower-income Americans, comes in at 73 percent. This is in sharp contrast to public views about private insurers, who are widely disliked if not hated and accused of denying essential care. Furthermore, if Medicare is socialism, then the whole U.S. health insurance system, with the government paying most of the bills and placing conditions on private insurers, is almost equally socialist. If you insist on calling any program the government pays for and regulates socialist, then U.S. healthcare would best be described as a partially privatized form of socialism. And one must ask, what is the point of the part that is privatized? Do private insurers add anything positive? Or are they simply parasites, skimming off money that could have been paying for care? The case for viewing insurers as parasites is strong. Many Medicare benefits are now delivered via Medicare Advantage, that is, plans paid for by the government but run through insurance companies. MedPAC, an independent advisory commission, estimates that last year Medicare Advantage plans were overpaid by $84 billion, thanks to practices such as “upcoding,” in which patients’ health problems are overstated to get larger sums from Medicare. Assessing the waste from employer-based insurance is harder, but most evidence suggests that private insurers have substantially higher administrative costs than Medicare does. Furthermore, the complexity of private insurance, with multiple payers all trying to deny care when they can, is a huge burden both on providers — doctors, nurses, and hospitals — and on patients. What do private insurers offer to compensate for these costs? One must go through intellectual contortions to avoid the conclusion that they are, in fact, parasites. Which brings me back to El-Sayed. In supporting Medicare for All, he’s basically calling for an end to the partial, parasitic privatization of a healthcare system that is already hugely dependent on public funding. When one looks at it that way, it’s not at all a radical proposal. Admittedly, the political lift requires overcoming the opposition to higher taxes to pay for Medicare for All. Political realism rather than economics was the reason I and many other progressives supported Obamacare, with all its complexities, rather than demanding an immediate move to Medicare for All. But the political calculus may very well have shifted since the 2000s, as Americans are fed up with a system of unaffordable premiums, rampant claim denials, and byzantine claim administration. Moreover, funding healthcare insurance through taxation would allow for a much more progressive distribution of the cost. That is, compared to the present system, middle-income households would pay less as high-income households would pay more. And the U.S. would stop wasting large sums on pointless administrative costs. So let’s be clear: El-Sayed’s healthcare platform is perfectly reasonable on the merits of cost, fairness and health efficacy. And with private insurers never more hated, while millions of Americans are losing their health insurance, 2026 may be its time. MUSICAL CODA
Insight: US fuel sales to Cuban business bring a glimpse of capitalism to Havana
Gasoline at $38 a gallon sold from cramped apartments. Diesel hawked on Instagram by a celebrity model to a reggaeton soundtrack. Six decades after Fidel Castro’s revolution, all of a sudden, capitalist cracks are appearing in Cuba’s communist energy sector.
Universities of Wisconsin wants to train 35K new health care professionals in next decade
The $90 million proposal will be included in the 2027-29 budget that is presented to the Wisconsin state Legislature and governor in the fall.
PUMA pop-up store and autograph sessions in Europark
On Theaterplatz until WednesdayFrom now until Wednesday, PUMA will have its own pop-up store on Theaterplatz in Europark station. In addition to selected PUMA products, you'll also find our latest jer...
NCSOFT profit beats forecasts as Lineage W drives sales to record
Webtoon Entertainment Inc., South Korean online giant Naver Corp.'s online comics platform, is betting on gaming with its first developer acquisition to t
Juventus rejects Arsenal’s advances for their key man
Juventus have insisted that Kenan Yildiz is not for sale this summer after Arsenal approached them about signing the talented attacker during this transfer window.The Gunners are searching for a marqu...
Barcelona-linked Premier League defender chooses to join Atletico Madrid
Cristian Romero has made a decision on his future The Argentine centre-back had interest from several clubs, most notably Atletico Madrid, Barcelona, Inter Milan and Arsenal, but according to reports ...
A right to buy a product?
A recent story in Colorado Politics caught my eye, as I learned of a “citizen initiative” that has qualified for the November ballot. It seems supporters of Initiative 177 have collected enough signatures, 146,165 legitimate ones out of a total of 189,508 collected, to clear the hurdle needed for a proposal to appear on the […]
Steve Hilton talks cutting costs, achieving balance in California politics
Republican gubernatorial candidate Steve Hilton joined KTVU to talk about his proposals for cutting costs in the state and achieving balance in California politics.
AGO Q2 Deep Dive: New Business Growth and Investment Volatility Shape Results
Financial guaranty insurer Assured Guaranty (NYSE:AGO) fell short of the market’s revenue expectations in Q2 CY2026, with sales falling 30.6% year on year to $195 million. Its non-GAAP profit of $1.23 per share was 23.2% below analysts’ consensus estimates.
'A little grace': Kate Beckinsale pushes back on comments about her weight loss
Kate Beckinsale pushed back on comments about her weight, opening up about grief, loss and a health condition.
Manhattan home health aide stabbed by client with dementia after serving her pancakes
Barbara Salberg, 66, was hit with a slew of charges including attempted murder following the stabbing in her luxury Upper East Side apartment.
Amazon asking town of Niagara for more in sales tax exemptions
Amazon is basing their request off the rising construction costs.
Saber's newest game trailer takes a shot at Gearbox's CEO, if you look closely
The first hint that something might be up with the recent debut trailer for Saber Interactive’s Rideshare Stimulator is an unusual choice of words—aside from that second one in the game’s title. “Don’t take your passengers too seriously,” the trailer’s narrator says, as he describes this upcoming game. It a car game about the gig work of driving eccentric people to their destinations, a riff on Crazy Taxi. And then, he says: “When I think I’ve met the randiest of passengers, someone even stranger gets in.” “Randiest”? That suggests “randy,” which usually means having strong sexual desire. Yet none of the oddball backseat occupants featured in the trailer seem particularly lustful. One is an old man who considers his grandson a failure, another shares the theory that birds might control traffic lights, another says he’s banned from an aquarium. A little later, there’s a license plate, shown 63 seconds into the trailer, on the front of an SUV: USB DRV It’s a Texas plate. The symbol between those letters is a cog wheel. If you know, you know. That’s a reference to Texas-based Borderlands game development studio Gearbox Software (their logo features a cog wheel). More specifically, it’s a reference to Gearbox’s CEO Randy Pitchford, who in 2018 found himself explaining the nature of video he’d saved on a USB drive that was found at a Medieval Times restaurant before being returned to the studio: “It was ‘barely legal’ porn. This girl’s handle was ‘Only 18.’” The “girl” in the video had committed a solo sex act that Pitchford, an avid practitioner of magic, found remarkable. “I realized, this is not a sex worker…This is a fucking magician.” Back then, the USB drive was central to competing lawsuits against Gearbox by the studio’s former lawyer and by Gearbox against him. A settlement in late 2019 “exonerated” Pitchford, per the Hollywood Reporter. The USB story has resurfaced at times, now in a trailer from a company that not long ago was corporate brethren with Gearbox. Saber vs. Gearbox The head of Saber told Game File that the reference is payback. “The dig is because Randy took shots at Embracer in Borderlands 4,” Saber CEO Matt Karch told me when I asked him about the license plate. “Without Embracer, Randy is performing magic tricks at birthday parties for a living.” Having interviewed Karch during a cross-country flight in late 2024, I can confirm that Karch was unimpressed with Pitchford during their time both working in the Embracer group. I’d approached him not out of surprise that there was animosity but that it was manifesting publicly now. Gearbox was founded in 1999, worked on a port of Halo early on, and developed hit series such as the loot-based sci-fi shooter Borderlands before it was purchased by The Embracer Group in early 2021 for $363 million (with a possible earn-out of over $1 billion, if certain targets were hit by 2027). Saber was founded in 2001, worked on a remaster of Halo early on, had a big hit with zombie shooter World War Z and was purchased by Embracer in early 2020 for $150 million, with a potential earn-out of up to $375 million. For a few years, the Embracer group was a voracious acquirer of game studios. Then, as investment dried up, it choked. In March 2024, Embracer sold Saber to an investment company controlled by Saber CEO Matt Karch, and it sold Gearbox in an all-stock deal to long-time Borderlands publisher Take Two Interactive. Other studios were shut down. Hundreds of developers were laid off. Gearbox didn’t say much about their Embracer experience, nothing too direct, at least. In the summer 2024, Pitchford told reporter and occasional Game File contributor Nicole Carpenter that Borderlands 4’s story was in some way thematically connected to Gearbox’s experience at Embracer: “There’s this cultural and emotional shift in me, personally, and at the studio. What does it mean to trade some autonomy for organization?” When Borderlands 4 came out, there was something stranger: the matter of “Embracer’s Bluff,” a location in the game featuring an AI-powered toilet and a large trash dump, according to a detailed Kotaku account of the place. Gearbox never commented on it; Take Two never got back to me about it when I asked them last year. By contrast, since Saber exited Embracer, Karch has been one of Embracer’s biggest defenders, casting their management as well-meaning and supportive despite the layoffs and studio closures that resulted from their excessive expansion. Like others, Saber’s Karch saw Embracer’s as a shot. With Rideshare Stimulator’s trailer, he’s returned fire. “It’s amazing to me how fast people forget those who went above and beyond for them,” Karch told Game File. A rep for Gearbox did not comment by press time. Game File is a reader-supported publication. Your backing makes my reporting—including any coverage of trailer-based beefs—possible. Good news! I’m currently running Game File’s first big sale of 2026. You can get a one-year subscription for 23% off. Click here to take advantage of the limited-time offer. And thank you for your support! Item 2: In brief… 🚫 Wal-Mart has laid off the staff of Restart, a games media outlet launched in 2024, Aftermath reports. 🟥 A GTA VI preview is on the way, at last, via an “extended look” that will premiere, unusually, on Netflix at 3pm ET on August 27, then officially go live elsewhere six hours later. Last week, Game File noted that Take Two label Rockstar Games is overdue for showing off GTA VI, based on the timing of the initial hands-off previews of GTA V and Red Dead Redemption 2. During a call with investors, Take Two CEO Strauss Zelnick said pre-orders for GTA VI were “unprecedented and astonishing,” but added the company can’t predict how many of those pre-orders represent bonus sales vs. sales that otherwise would have been made at launch. During the same call, Zelnick was noticeably bullish on the future of playing games over streaming cloud connections (predicting wider adoption in three or so years). He sounded unbothered by Sony’s plans to stop making discs for new games (he said the business is 90% digital already and predicted that there could still be limited edition physical editions of games “in the same way there’s still vinyl in the recorded music business.”) 👀 Take Two wrote off $43 million in their spring quarter after deciding “not to proceed with further development of an unannounced title in its pipeline from a third-party developer.” 🤔 Some rare age-demographics from a big publisher: Capcom recently told investors that “users in their 20s account for approximately half of the users of both Pragamata and Resident Evil Requiem.” Item 3: The week ahead Tuesday, August 11 Game releases: The Elder Scrolls IV: Oblivion Remastered (Switch 2; already out for PC, PS5, Xbox) continues the Bethesda strategy of putting Elder Scrolls games on everything; Royalty Free-For-All is a Smash Bros.-style fighting game featuring public domain characters such as Mother Goose brawling with Oliver Twist in a stage based on the original Little Shop of Horrors movie. Wednesday, August 12 Game release: Pro Jank Footy (PC, console) is an arcade-style Australian Rules Football game with increasingly ridiculous rules, the more you play (I enjoyed the Steam demo) Thursday, August 13 Game release: Super Mario Sunshine (Switch 2, originally released in 2002 on the GameCube) is released for Switch 2’s Nintendo Switch Online service. This game is the black sheep of 3D Mario games. It’s the successor to the breakthrough Super Mario 64 and the rare Mario game built around a single (vacation resort) theme. Mario’s got a water-spraying backpack, a Yoshi pal and a lot of blue coins to collect.
Hims & Hers Health (NYSE:HIMS) Exceeds Q2 CY2026 Expectations But Stock Drops
Telehealth company Hims & Hers Health (NYSE:HIMS) reported revenue ahead of Wall Street’s expectations in Q2 CY2026, with sales up 38.2% year on year to $753.2 million. On top of that, next quarter’s revenue guidance ($890 million at the midpoint) was surprisingly good and 12.4% above what analysts were expecting. Its GAAP loss of $0.37 per share was significantly below analysts’ consensus estimates.
Someone Made a Terrific Deal in the Peacock/YouTube Premium Partnership…But Who?
(Welcome to the “Most Important Story of the Week”, my bi-weekly strategy column analyzing the most important (but often not buzziest) news story of the last two weeks. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. Please subscribe.) I hope everyone around the world suffering from record heat waves is doing okay. The temperature is already up in Southern California, but obviously not nearly as bad as parts of Europe. With a super El Nińo coming this year, I worry it will get even worse. Yes, we know what’s causing this heat—it’s the carbon, duh—but we really aren’t making enough progress. I’m not “environmental strategy guy”, but if I were, I’d have some ideas of what I’d try. Honestly, for years I’ve been intrigued by the work of the folks at MEER—whose plan, super simply, is to put up mirrors to reflect heat (while continuing the important work of decarbonization)—but I’m frustrated this idea hasn’t made more progress. (Other geo-engineering groups seem to get better press.) With heat like this—cancelling events, hurting economies and, most importantly, killing people—it seems like the time to push solutions! The “mirrors on the ground” solution has barely been tried.1 While entertainment companies may not “feel the heat”, lots of outdoors/experiential industries—concerts, theme parks and so on—will. Even movie theaters could benefit, since mirrors could help lower AC costs, which I imagine is not an insignificant expense, especially in the hotter areas of the country. So I do think the entertainment industry should prioritize this issue. Anyways, let’s get back into the entertainment strategy. I was about to write, “Hey, this week we don’t have any mergers and entertainment news to dive into,” but that’s not really true, since we had more updates on Paramount-Skydance and Warner Bros. Discovery. But the big story of the week involves a streamer and a Big Tech platform bundling their respective streamers. So I’ll write about the updates on Paramount buying Warner Bros., Versant making some moves, and a whole lot more. But we start with a surprising deal: Peacock licensing their content to YouTube Premium. Let’s dive in! Subscribe Most Important Story of the Week - Peacock’s Pricey Premium Partnership The story of the week is Comcast’s2 NBC-Universal’s Peacock making a deal with Google’s YouTube’s YouTube Premium subscription product to embed their content. And I’ll say this up front: Someone made a terrific deal. The question is who. And I’ll be honest: I don’t know. Let me explain why, including why this deal exists, the pros and cons for each side, the biggest unknown, and what that says about the streaming wars. Customers Love Bundles (But YouTube Has Its Own Issues) We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… Why customers love bundles… But why I’m worried about YouTube’s integration... How Peacock is trading scale for control… And the reason they likely made this deal... The odd budget math for this deal... Whether or not I think the Paramount-Skydance/WBD deal is more likely after the latest settlement... Versant making moves and why that’s good for Hollywood… Another distributor going out of business… ...and a whole lot more! ...please subscribe! We can only keep doing this great work with your support.
Trump officials propose new requirements for food additives and ingredients
U.S. health officials want food manufacturers to provide more information about new additives and ingredients. Under a proposal announced Monday, food companies would have to notify the Food and Drug
Oregon lawmakers condemn reported attack against Sen. Janeen Sollman
Sen. Janeen Sollman was reportedly verbally and physically accosted by a man on Aug. 8, prompting bipartisan condemnation of political violence.
NIL bill advocates see goal line in sight after recess
After 16 wild hours that ended with a bipartisan college sports bill being punted in the middle of the night, President Donald Trump’s involvement was not enough to trigger votes on legislation he would like to add to his midterms and legacy sales pitches. As senators and senior aides bickered and postured all day and […]
RFK Jr. proposes rule to increase food ingredient oversight
The health secretary's proposal would overhaul a 1958 law that allows companies to self-affirm ingredients are safe
Nearly 20 products issued health alert: ‘Should be thrown away’
These products contain the jalapeños at the center of the current salmonella outbreak.
HeyDay Entertainment to close Norman location after sale to OTA
HeyDay Entertainment announced Monday that it will close its Norman location to the public Aug. 28 after reaching an agreement to sell the property to the Oklahoma Turnpike Authority for
Business Monday: Multigenerational farm Lions Gate Coffee looking for new owners
The Lions Gate turnkey sale offers established distribution across the mainland and internationally, along with name-brand recognition.
Dodgers’ Late-Season Slide Complicates MLB’s Salary Cap Push
The two-time defending champions haven’t been a juggernaut lately.
NFIB backs small-business 'champion’ María Elvira Salazar for re-election in CD 27
‘South Florida runs on small business.’
Commentary: Forfeited properties can and should be redeveloped
Properties lost through tax sales have potential to be put back on the tax rolls and become an opportunity for community revitalization and more affordable housing.
Farmer trusted AI after it gave good advice, then it helped wipe out 25 acres of his crops
The 67-year-old farmer was recommended by the AI to use high-efficiency flupyrimethalin and flusulfasulfaether to kill weeds and mix it with thiamethoxazine and methyl salt. As reported...
AbCellera women’s health data top ‘most aggressive upside scenario,’ putting Astellas and Bayer on notice
AbCellera has reported phase 2 results “beyond even the most aggressive upside scenario” that its CEO dared to consider, boosting the biotech’s chances of challenging Astellas and Bayer for a women’s health market. The phase 2 clinical trial compared ABCL635, an antibody targeting NK3R, to placebo in patients with hot flashes caused by menopause. Investigators enrolled 92 postmenopausal women experiencing a mean of about 10 moderate or severe hot flashes per day. By Week 4, the number of moderate or severe hot flashes had fallen by a mean of 8.8 on ABCL635 and by 3.5 on placebo. That statistically significant, placebo-adjusted reduction of 5.3 hit the trial’s primary endpoint. The level of efficacy also cleared the bar set by existing drugs. While cross-trial comparisons can be misleading, AbCellera CEO Carl Hansen, Ph.D., had seen enough to start hyping the program. “We now view ABCL635 as a potential best-in-class non-hormonal therapy with strong differentiation against approved NK3R competitors across all important dimensions, including efficacy, safety, dosing and convenience,” Hansen said on a Monday morning conference call with investors to discuss the data. “We believe ABCL635 is now a highly de-risked program.” Last week, Hansen used AbCellera’s earnings call to set expectations for readout, with the CEO defining success as a clean safety profile and efficacy comparable to the two approved small molecules. The data vaulted over that bar. Astellas linked (PDF) one of the small molecules, Veozah, to placebo-adjusted reductions in hot flash frequency of 2.1 and 2.6 at Week 4 of its two phase 3 trials. Bayer reported (PDF) placebo-adjusted reductions of 3.04 and 3.29 at Week 4 of pivotal studies for its small molecule, Lynkuet. At 5.3, the placebo-adjusted reduction in AbCellera’s trial comfortably cleared the standard set by the incumbents. Veozah and Lynkuet came to market based on evidence of their ability to reduce the frequency and severity of hot flashes. AbCellera’s phase 2 study covered both endpoints, with the Canadian biotech reporting a mean reduction in severity of 1.4 points at Week 4 on ABCL635, compared to 0.3 points for placebo. Again, the placebo-adjusted result compares favorably to data on Veozah and Lynkuet. Analysts shared Hansen’s enthusiasm for the data. The phase 2 results “firmly validate ABCL635 as a potentially best-in-class treatment,” BMO Capital Markets analysts said in a note to investors Monday. ABCL635’s apparent efficacy edge “is likely attributable to the higher dosing/target engagement the asset is able to reach vs. the oral agents due to its wider therapeutic index,” the analysts added. The analysts, who model $2.3 billion in unadjusted peak sales for ABCL635, flagged the safety profile as another positive of the phase 2 readout. While Veozah carries a boxed warning for liver damage, nobody on ABCL635 in the phase 2 trial had elevated liver enzymes or bilirubin values. If replicated in phase 3, the lack of a liver signal could allow approval without the monitoring requirements imposed on Veozah. Investors appeared equally enthused, sending AbCellera's stock up 32% to $9.21 in premarket trading Monday from a Friday closing price of $6.93. Next, AbCellera will collect the Week 12 data and talk to its advisors about further development. The results open up “a wide variety of possibilities of how we might take this forward into phase 3 studies to truly maximize the value of the asset and make sure that ABCL635 is able to demonstrate its differentiation potential,” Sarah Noonberg, M.D., Ph.D., AbCellera’s chief medical officer, told investors.
Boeing to Sell 3 Autonomous Flight Subsidiaries
In exchange for the sale to Archer Aviation, which is developing a piloted electric aircraft, Boeing will receive a 16.5 percent stake in Archer.
Louisiana health officials warn of vibrio case rise
🚨 A jump in Vibrio vulnificus cases is prompting Louisiana health officials to urge caution around certain exposures to salt water and raw seafood. The bacteria is known for causing a "flesh-eating" infection. Nine people have been hospitalized, and five have died this year, officials said Thursday. (Press release)
India's Zee Entertainment posts quarterly profit drop on weak ad sales, rising costs
India's Zee Entertainment Enterprises reported a 46.9% fall in quarterly profit on Monday, hurt by weak advertising revenue and higher costs related to its return to sports broadcasting.
Top salaries at Erie Family Health 2024
The Federal Qualified Health Center serves about 94,000 mostly low-income patients at 13 locations.
Forget about being cool, Whitmer Thomas just wants to make his friends laugh
Comedian Whitmer Thomas’ new special, “The Terminal Crew of Dudes,” trades cool-guy posturing for a heartfelt salute to loyalty, lifelong friendships and the stories that bind them.
Off-campus student housing is big business, especially in the shadows of LSU
Some of the highest rents, occupancy rates and sales prices in the state are for high-end apartment complexes catering to students in the shadows of LSU.
Taylor Farms issues recall for over 12 items over Salmonella risk
Taylor Farms is pulling prepared food items containing jalapeños because of concerns of Salmonella, a bacteria that can cause painful food poisoning.
COLL Q2 Deep Dive: ADHD Expansion and Pain Business Headwinds Shape Guidance
Pharmaceutical company Collegium Pharmaceutical (NASDAQ:COLL) fell short of the market’s revenue expectations in Q2 CY2026, but sales rose 6.3% year on year to $199.9 million. The company’s full-year revenue guidance of $840 million at the midpoint came in 3.4% below analysts’ estimates. Its non-GAAP profit of $1.92 per share was 8.8% above analysts’ consensus estimates.
Best Trade Partners Named for Kings Veteran Lavine
Trapped by a massive $49 million salary, Sacramento searches for a viable exit. Discover which rebuilding franchises could finally absorb the veteran guard to spark a youth movement.
Salem Health Cleared to Take Over Smaller Santiam System
Research shows prices often go up when health systems consolidate. But the parties say the deal with bolster their operations for the long haul.
PHOTOS: Metro Health offers back-to-school vaccines for Immunization Awareness Month
WOAI NBC News Channel 4 San Antonio provides local news, weather forecasts, traffic updates, investigations, and items of interest in the community, sports and entertainment programming for San Antonio and nearby towns and communities in South Central Texas, including Windcrest, Uvalde, Universal City, Somerset, Seguin, Schertz, San Marcos, Sabinal, Poth, Poteet, Pleasanton, Pearsall, New Braunfels, Live Oak, Kerrville, Hondo, Helotes, Goliad, Fredericksburg, Floresville, Eagle Pass, Devine, Del Rio, Cuero, Crystal City, Converse, Cibolo, Castroville, Carrizo Springs, Boerne, Bandera.
Minnesota woman sues Chipotle after burrito bowl allegedly caused Salmonella infection, sepsis
A Minnesota woman is suing Chipotle after allegedly contracting Salmonella from a burrito bowl, as health officials investigate a multistate outbreak tied to recalled jalapeños.
California nearly achieved universal healthcare. Now, millions are losing coverage
Facing budget shortfalls and new federal restrictions, state leaders have begun rolling back the coverage system they built.
A Man Sold His Business For $1.4 Million. Then His Brother-In-Law Wanted To Invest It 'For Free'
A man in Arizona sold the auto repair shop he spent 27 years building for $1.4 million after receiving an offer from a larger regional chain. Within a week of the sale closing, his wife’s brother, who actively trades individual...
Health expert sounds alarm over rising outbreaks
NYU Langone gastroenterologist Dr. David Bernstein analyzes the Cyclospora and Salmonella outbreaks linked to contaminated produce. He details key symptoms, infection sources and essential food safety tips.
Man, 41, Inherits $2 Million From Parents — His Wife Wants To Put Half Into Her Sister's Struggling Business
A 41-year-old man in Georgia inherited $2 million after both of his parents passed away within a year of each other. The inheritance came from a combination of investment accounts, life insurance proceeds and the sale of the family home....
Public health alert issued related to potential salmonella contamination recall
The U.S. Department of Agriculture’s Food Safety and Inspection Service (FSIS) has issued a public health alert, specifically targeting meat and poultry products that contain FDA-regulated jalapeños that could be
Is Accel Entertainment (ACEL) A Bargain As Earnings Growth Lifts Valuation Hopes?
Accel Entertainment (ACEL) is attracting fresh attention after its 4 August 2026 earnings update, which showed higher sales, revenue and net income for both the quarter and first half compared with the prior year. See our latest analysis for Accel Entertainment. At a share price of $12.16, Accel Entertainment has posted a 6.95% year to date share price return and a 10.34% 1 year total shareholder return, which suggests moderate positive momentum heading into the latest earnings and capital...
A new ceramic Apple Watch could go on sale soon
Bloomberg’s Mark Gurman wrote today that Apple is planning a return of the much-beloved ceramic Apple Watch. In fact, Gurman...
Saline County business gives back with free school supplies, meals for families
A local business is helping families prepare for the new school year while continuing its effort to fight food insecurity across Saline County.
Simmons Foods promotes 2 executives, creates chief commercial officer position
Siloam Springs-based Simmons Foods has promoted Scott Salmon, president of Simmons Pet Food, to the newly created role of chief commercial officer and that Jacob Rogers will succeed him. Salmon...
Four 49ers Position Battles Still Ongoing at Training Camp
The San Francisco 49ers have one of the most talented rosters in the league. There are a few interesting position battles going on, though, such as at left guard and free safety. A month ago, it was assumed that Mike Evans and Ricky Pearsall would be the top two options and it would be a solid room.
Planning & Zoning Commission To Review CHRISTUS Health Site Plan For Adoption Aug. 12 For Two-Story Medical Facility At 401 Trinity Drive In Los Alamos
The public notice for the new Christus facility at 401 Trinity Drive in Los Alamos. Photo Courtesy LAC How the proposed CHRISTUS Health facility is expected to look when it is finished in late 2027…
Public health alert for various meat and poultry products containing recalled jalapeños
Products distributed across a number of states, including one product in Florida, could be contaminated with salmonella.
Video Health alert for meat and poultry potentially linked to a salmonella outbreak
Federal officials have issued new public health warnings on meat products with recently recalled jalapenos, potentially linked to salmonella in more than two dozen states.
Small Business Technology News This Week: AI Shopping Searches Surges, Thryv And Wix Partner, Gemini Notebook Gets An Upgrade
AI adoption is accelerating across commerce and industry, as new partnerships and tools help businesses improve sales, cash flow, productivity and efficiency.
A restaurant made for and by its customers
The menu also offers hot dogs, an assortment of French fries including sweet potato along with classic wraps featuring. You’ll also find offerings of salads, sandwiches and soups on the menu and plenty of beer choices. Indoor and outdoor s…
Lubbock business news includes restaurant closure, hotel sale
Business Reporter Alana Edgin reviews recent Lubbock area businesses news and hints at upcoming articles in the Around the Hub column.
Here’s When Apple Will Reveal Its iPhone 18 Pro Special Event
Apple’s next iPhones will go on sale in just over a month. But when should you start looking out for the confirmation of the special event? Here’s all you need to know.
Deals: Galaxy Z Flip8 gets a discount out of the gate, Z Fold8 and Z Fold8 Ultra also on sale
The Z Fold8 duo briefly had a massive discount at checkout, but Amazon reconsidered. We also have a look at Motorola's Razr foldables.
UFC Vegas 120 Bonuses Are Revealed
Following the UFC Vegas 120 card on Saturday night at Meta Apex in Las Vegas, we learned which fighters took home the post-fight bonuses. Check out all of the bonus winners for the evening below. Performance of the Night ($100,000 to the fighter): Quillan Salkilld In the main event of UFC Vegas 120, Quillan Salkilld […] The post UFC Vegas 120 Bonuses Are Revealed appeared first on HEAVY.
Ashford embracing return to central Cardiff role
Cardiff City forward Cian Ashford is enjoying playing in a more central role following his eye-catching performance in the Bluebirds' Carabao Cup win over Swindon. The 21-year-old assisted Yousef Salech for the second goal in the 3-2 win and was also denied by the crossbar. Ashford spent many years playing in a central role with Cardiff's academy but his minutes for the first team have almost exclusively come on the wing.
Public health alert issued for meat and poultry products containing recalled jalapeños
The U.S. Department of Agriculture’s Food Safety and Inspection Service is issuing a public health alert for meat and poultry products containing Food and Drug Administration-regulated jalapeños that may be contaminated with Salmonella.
Public health alert issued for meat and poultry products containing recalled jalapeños
The U.S. Department of Agriculture’s Food Safety and Inspection Service is issuing a public health alert for meat and poultry products containing Food and Drug Administration-regulated jalapeños that may be contaminated with Salmonella.
Public health alert issued for meat and poultry products containing recalled jalapeños
The U.S. Department of Agriculture’s Food Safety and Inspection Service is issuing a public health alert for meat and poultry products containing Food and Drug Administration-regulated jalapeños that may be contaminated with Salmonella.
Public health alert issued for meat and poultry products containing recalled jalapeños
The U.S. Department of Agriculture’s Food Safety and Inspection Service is issuing a public health alert for meat and poultry products containing Food and Drug Administration-regulated jalapeños that may be contaminated with Salmonella.
Public health alert issued for meat and poultry products containing recalled jalapeños
The U.S. Department of Agriculture’s Food Safety and Inspection Service is issuing a public health alert for meat and poultry products containing Food and Drug Administration-regulated jalapeños that may be contaminated with Salmonella.
Public health alert issued for meat and poultry products containing recalled jalapeños
The U.S. Department of Agriculture’s Food Safety and Inspection Service is issuing a public health alert for meat and poultry products containing Food and Drug Administration-regulated jalapeños that may be contaminated with Salmonella.
Public health alert issued for meat and poultry products containing recalled jalapeños
The U.S. Department of Agriculture’s Food Safety and Inspection Service is issuing a public health alert for meat and poultry products containing Food and Drug Administration-regulated jalapeños that may be contaminated with Salmonella.
Could Orlando Magic Have a Huge Roster Shakeup?
Pressure mounts as postseason failures linger. While the star duo remains secure, underwhelming results could force the front office to sacrifice key starters to salvage Orlando’s timeline.
Frankie Grande praises sister Ariana Grande following hiatus announcement: ‘I will have your back until the end of time’
Frankie Grande shared a message of support for his sister Ariana Grande after she announced she would ‘step back from visibility.’
Auto loan refinancing: How it works and when it could save you money
Explore how auto loan refinancing works, when it makes financial sense, and how preapproval options can help lower your monthly car payments.
Salkilld Vs. Gamrot Odds, Full Fight Preview & Prediction
Ultimate Fighting Championship (UFC) Lightweight standouts Quillan Salkilld vs. Mateusz Gamrot will clash TONIGHT (Sat., Aug. 8, 2026) inside Meta Apex in Las Vegas, Nevada, for UFC Vegas 120. Salkilld is the brightest Australian prospect in quite some time. In less than two years on UFC’s roster, Salkilld has racked up five wins and four […]
Fauci contempt vote reflects the enduring politics of COVID
Republican lawmakers and Secretary of Health RFK Jr. continue to scrutinize the legacy of COVID-19, recently voting to hold retired immunologist Anthony Fauci in contempt after his refusal to testify before a Senate committee.
Protect Your Business With This 2-Part AdGuard Bundle, on Sale for $40
Two days left: Get five years of VPN protect and a lifetime without ads.
Meteorite that smashed through a New Jersey roof reveals clues to life’s origins
A rare meteorite that crashed through a New Jersey roof contains evidence of ancient salty fluids, organic compounds, and amino acids from a primitive asteroid. Its pristine chemistry could offer new clues about how space rocks helped supply early Earth with some of the ingredients needed for life.
12 Gadgets To Steer Clear Of At Garage Sales
Garage sales are a great way to pick up a significant value, but make sure to steer clear of these 12 gadgets when bargain hunting.
Scientists Watched Carbon Dioxide Being Pulled Out of The Air to Form Graphite
This is some seriously high-tech upcycling.
Rhea Lana's consignment event, Latino music comes to Victorville fairgrounds
August brings the Marinelli Bros. Circus, a consignment sale, and a Latino concert to the Victorville fairgrounds.
Here’s When Apple Will Reveal Its iPhone 18 Pro Special Event
Apple’s next iPhones will go on sale in just over a month. But when should you start looking out for the confirmation of the special event? Here’s all you need to know.
UFC Vegas 120 Results: Gamrot vs. Salkilld
Mateusz Gamrot, Quillan Salkilld clash in UFC Vegas 120 main event
East Austin business owner impacted by construction
One East Austin business owner says construction near her restaurant is making it harder for customers to get to her business and its hurting sales.
Taiwan’s push to dissolve pro-Beijing party triggers political censorship debate
Politicians divided over proposal to ban Chinese Unification Promotion Party after ministry says it jeopardises free and democratic constitutional order.
Oregon DOJ approves Salem Health, Santiam Hospital merger
The Oregon Department of Justice on Aug. 7 approved the merger between Salem Health and Santiam Hospital, paving the way for the systems to combine.