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Markwayne Mullin confirmed to lead Department of Homeland Security
The Oklahoma Republican faced a glide path to confirmation with the help of two Democratic senators.
Markwayne Mullin confirmed to lead a DHS in turmoil
Markwayne Mullin will serve as Donald Trump’s next Department of Homeland Security secretary, elevating the US senator to helm the agency at the center of the president’s controversial immigration enforcement effort and an ongoing shutdown.
‘Don’t Make Any Deal’: Trump Tells Republicans to Hold Firm on Shutdown Talks
The president is using the standoff over funding the Department of Homeland Security as leverage to pass a strict voter ID bill. Critics say the bill would place an undue burden on eligible voters.
Scientists Say Surprising Smells Are Unlocking the Secrets of Ancient Mummies
Analyzing samples of mummies from different dynastic periods showed how the mixtures of substances used in mummification became more complex with time.
Airport chaos is adding urgency to the DHS shutdown debate. But who has the leverage?
DHS has been shut down for more than a month. But extremely long and growing TSA wait times have created newfound political urgency to reach a deal.
Uplifting and Not Ceding Ground on Health Equity Practice Is Critical to Strengthening Public Health and the Health of the Nation
Public health science gains in the last quarter century in the United States have been formidable due to a focus on structural and social determinants of health, thereby enhancing understanding of the role of inequitable policies in shaping health inequities and inequitable access to ameliorative resources.
Thousands in taxpayer funds spent on horse, hair and makeup expenses for Kristi Noem’s Mount Rushmore ad
Tens of thousands of taxpayer dollars were spent on expenses for hair and makeup artists and a horse for the advertisement showcasing outgoing Department of Homeland Security Secretary Kristi Noem in front of Mount Rushmore, according to invoices seen by CNN.
Trump was offered an off-ramp to the DHS shutdown but he didn’t take it
President Donald Trump was presented Sunday with a potential off-ramp to the more than month-long Department of Homeland Security shutdown: fund every part of the department except enforcement operations by Immigration and Customs Enforcement, two sources familiar with the conversations told CNN.
Revolutionary Submarine Mysteriously Disappears Without a Trace – Scientists Are Now Preparing for a Bold Return
A pioneering robotic submarine that explored beneath Antarctica’s glaciers has been lost, but its discoveries are reshaping our understanding of ice melt as a more advanced successor is prepared to continue the mission.
Exit polls suggest Italy's Meloni has narrowly lost justice referendum vote
Exit polls on Monday suggested Italian Prime Minister Giorgia Meloni had narrowly lost a referendum on her flagship reform of the judicial system, dealing a potential blow to the ruling coalition ahead of next year's general election.
Melton Little lands Jack May's endorsement in open HD 71 race
'I know he will fight for conservative principles.'
Toto Wolff: Mercedes team principal wary of 'politics' as Charles Leclerc makes 'extremely strong' Silver Arrows claim
Scientists Trap Light in a Layer 1,000x Thinner Than a Hair
Scientists have found a way to trap light in an extremely thin layer, potentially reshaping how future photonic devices are built.
Arizona Diamondbacks Spring Training Gameday Thread, #30 @ Padres
Roster moves The Arizona Diamondbacks made the following roster moves and have 33 players in camp. Optioned to Triple-A Reno: Reassigned to Minor League camp: The first of these is a bit of a surprise. Only yesterday, I was noting how Abner seemed to have the inside track for left-handers job, after the recent meltdowns […]
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Politics chat: Trump's mixed messages on the Iran war, the latest on DHS funding
We look at President Trump's mixed messages on the war with Iran, plus the latest on Department of Homeland Security funding, which Congress has frozen over his immigration enforcement policies.
Trump threatens to deploy ICE agents to airports Monday if funding deal isn’t reached
President Donald Trump said Saturday he will deploy Immigration and Customs Enforcement agents to US airports on Monday if an agreement isn’t reached to fund the Department of Homeland Security amid a partial government shutdown.
Ole Miss eyes May decision on VaughtHemingway entertainment district partner
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One arrested, another cited in shoplifting incident at business on East Avenue in Chico
CHICO, Calif. - A Paradise man was arrested and a Forbestown woman was cited by Chico Police in connection to a shoplifting incident at a business in Chico.The Chico Police Department says that at around 12:30 p.m. on Wednesday, March 18, a loss prevention employee observed two suspects stealing several items from a retail business on the 700 block of East Avenue in Chico.Upon exiting the building, the two suspects, a man and a woman, were contacted by the loss prevention employee regarding the stolen items. The employee was able to persuade both suspects to return to the store and hand over the items they had stolen.Authorities say the business expressed their desire to press charges against the suspects and contacted Chico Police to report the crime.Officers reviewed video surveillance that confirmed the employee's account of what happened. Officers then made arraignment for both suspects to turn themselves in the following day.When the suspects, identified as 51-year-old Jamie Leal of Forbestown and 62-year-old Melvin Royal of Paradise, arrived the next day to turn themselves in, authorities say both admitted to their involvement in the incident and elected to write handwritten apology letters to the business.Leal was cited by Chico Police on a misdemeanor charge of shoplifting.Royal was taken into custody and transported to the Butte County Jail, where he was booked on the following charges:Shoplifting with 2+ priors (felony)Shoplifting (misdemeanor) googletag.cmd.push(function() { googletag.display('ad-1514992'); });
Excess Heat Raises Tijuana River Valley Hydrogen Sulfide Emissions, Health Precautions Recommended
People in the South Bay, especially those living near the Tijuana River Valley (TJRV), are experiencing elevated hydrogen sulfide (H2S) emissions, often recognized by a strong rotten egg smell.
These are the women exec moves you need to know across sports, finance, and media
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US intel finds no China plan to invade Taiwan by 2027, despite military buildup
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Splenda manufacturer eyes $91M in upgrades to Indianapolis operations
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Political tug of war over Iranian women's soccer team prompts criticism in Australia
MELBOURNE, Australia (AP) — The United States and Australia’s political tug of war against Iran over the fates of seven members of the Iranian women’s soccer squad appears to have ended with the depleted team returning home minus the two players who defected last week.
Pittsburgh Pirates vs. Athletics - Live Score
View the Pittsburgh Pirates vs. Athletics game played on June 17, 2026. Box score, stats, play-by-play timeline, highlights, odds & more
New dispute emerges around Subnautica 2’s early access release
Lawyers for the ousted—and now partially reinstated—leadership team of Unknown Worlds, the studio behind Subnautica 2, are crying foul over news that the game will be released into early access in May. The release announcement earlier this week was made improperly, potentially “damaging the game and sowing additional confusion among the Subnautica community,” the lawyers said in a letter sent on Tuesday to Vice Chancellor Lori Will of Delaware’s Court of Chancery. In their letter, the lawyers also floated the idea of asking Will to find Krafton in contempt of the court’s ruling. The letter was sent just one day after Will’s bombshell ruling that publisher Krafton had breached its contract with Unknown Worlds’ executive team, when it fired them last June. The new issue isn’t necessarily the May early access timeframe, but how the news was announced. The letter and Krafton’s response have not been previously reported. A quick recap of prior events: Subnautica 2 is an unreleased, underwater survival adventure and the most-wishlisted game on Steam. Last year, longtime Unknown Worlds CEO Ted Gill, along with studio co-founders Charlie Cleveland and Max McGuire, were fired by Krafton. They swiftly sued, saying the publisher had terminated them to avoid paying out up to $250 million in potential performance-based bonuses. The studio leaders had hoped to earn that with an early access release of the game, which Krafton had blocked. The publisher argued in court that Subnautica 2 wasn’t ready, which the ousted execs disputed. On Monday, Will ruled that Krafton had violated its contract, firing the execs to avoid the performance payouts, and that it had to reinstate Gill and give him full authority over any early access release for Subnautica 2. On Tuesday, IGN reported on a new memo issued that day to Unknown Worlds staff by Steve Papoutsis, the executive Krafton had put in charge of Unknown Worlds after the 2025 firings. In the note, Papoutsis said that Subnautica 2 had passed a key development milestone “last week” and that he and Krafton had determined the game “is ready for Early Access release in May.” This news appeared to catch the lawyers for Gill, Cleveland and McGuire by surprise. On Tuesday night, they sent a letter to Will expressing “serious concerns” about whether it would be possible to forge an agreement with Krafton consistent with the judge’s order. Papoutsis’ memo was a problem, they wrote. He didn’t have the authority to declare anything about Subnautica 2’s release. As of 9am ET on Monday, March 16, the effective date of Will’s order, Papoutsis wasn’t CEO of Unknown Worlds. Gill was. And, per Will’s order, only Gill could make Subnautica 2 release decisions. They continued: Krafton self-servingly announced the launch without any regard to its impact on the game, the team, or the community—let alone this Court’s Opinion. Announcing the release of a game is momentous, and it is typically accompanied by significant marketing activity, fanfare, and community coordination. And most importantly, the announcement is carefully designed to maximize excitement for the game. That entire process was supposed to be driven by Mr. Gill. However, in defiance of the Court’s Opinion, Krafton has now taken that away, further damaging the game and sowing additional confusion among the Subnautica community. The lawyers speculated that Krafton had “intentionally leaked” Papoutsis’ memo and then issued an official statement to confirm the leak. Game File is a reader-supported publication. My reporting is only possible through support from readers like you. To support my work, consider becoming a free or paid subscriber. Subscribe On Wednesday, lawyers for Krafton defended their client in their own letter to vice chancellor Will, saying nothing they did violated her order nor showed contempt: Papoutsis’s message was simply celebrating the UW employees’ efforts toward a past event: Krafton’s pre-Opinion determination that Subnautica 2 was ready for Early Access release. There was nothing improper about conveying the results of the milestone review or thanking the development team for their dedication and talent. They added that Gill could still make his own call about Subnautica 2’s release: In his role as CEO, Gill will be able to assess independently his views on the state of Subnautica 2 and the appropriate release schedule; nothing in Papoutsis’s message alters Gill’s authority or discretion. Vice chancellor Will has not responded to the letters and doesn’t necessarily have to. Both parties were previously ordered by Will to confer this week and submit a proposed judgment consistent with her ruling. The letter from Gill’s attorney’s this week doesn’t indicate whether he would or would not support a May release for Subnautica 2. But it could limit his options. And, if Gill’s lawyers are right, the lack of marketing fanfare around the leak of the May date could dull the launch of the game. Any harm to Subnautica 2’s launch is an extra sensitive issue given the context of the legal dispute: millions of dollars of payouts are on the line, tethered to the scale of the game’s initial performance. In her ruling on Monday, Will noted that there was obvious “bad blood” between Gill’s side and Krafton but that the two would need to work together: “They can—and must—act in good faith to navigate their remaining contractual relationship.” Item 2: A new kind of couch co-op game A highlight of GDC each year is the Alt.Ctrl showcase that features games played with extremely experimental controllers. Perusing this year’s offerings last Friday, I found a game controlled with giant scissors, another with big toothbrushes and one that amounted to dumpster diving. My favorite was Pivot, a co-op game about collectively maneuvering a couch. It was developed by students at the University of Utah’s masters of arts and engineering games program. Players lift and tilt the physical couch in order to control the position of a virtual one. That virtual one is moving through an obstacle course on-screen, while being pursued by a giant skull. Developer Nishant Verma told me at GDC that the couch is made of styrofoam (this became more evident as I watched!) and that the name was a riff on an episode of the sitcom Friends. Item 3: In brief… 🚫 Ubisoft is laying off more than 100 workers at its Red Storm studio, as the North Carolina location known for decades for its Tom Clancy games, ceases in-house game development, VGC reports. 👀 On Monday, Nvidia’s revealed its DLSS 5 AI-driven graphics technology that purports to improve game graphics… and it has been roasted about it by the media and the online gaming public for the remainder of the week. The tech changed the faces of characters in footage from Resident Evil Requiem, Hogwarts Legacy and EA Sports FC, drawing accusations of giving carefully art-directed games the generic look of AI “slop.” Nvidia CEO Jensen Huang had said on Monday that “DLSS 5 is the GPT moment for graphics—blending handcrafted rendering with generative AI to deliver a dramatic leap in visual realism while preserving the control artists need for creative expression.” By mid-week, Huang was telling Tom’s Hardware that the new tech’s critics were “completely wrong” because game-makers could still “fine-tune the generative AI” to suit their game’s aesthetics.
What a day at a gas station in Pennsylvania reveals about the midterms: From the Politics Desk
Plus, an update on the talks to end the Department of Homeland Security shutdown.
Humans and animals have the same preference in mating calls, citizen science experiment finds
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Trump launches investigation of states that mandate health insurance covers abortion
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De'Anthony Melton shares honest reply about uncertainty of his Warriors future
De'Anthony Melton discussed the uncertainty of his future with the Golden State Warriors as he is expected to enter unrestricted NBA free agency.
DAVID MARCUS: Liberal wives, not conservative husbands, rule the political roost
Conservative radio host alleges liberal wives control their husbands' politics, citing examples from Joe Kent to Jimmy Kimmel in controversial social media post.
Something extremely weird is happening to our galactic neighbor. Scientists think they know why
The stars in the Small Magellanic Cloud aren’t behaving the way they should. A cataclysmic collision with another nearby galaxy may be the culprit
Political operatives with Trump ties raked in millions of dollars in commissions from DHS ad campaign
The ads became a sore spot within the White House over Kristi Noem.
Pittsburgh Pirates vs. Athletics - Live Score
View the Pittsburgh Pirates vs. Athletics game played on June 16, 2026. Box score, stats, play-by-play timeline, highlights, odds & more
One 'freaking snake' and no apologies: How the Mullin hearing went off the rails
Senator Rand Paul has made it clear he has little regard for President Donald Trump’s nominee to lead the Department of Homeland Security, fellow Republican Senator Markwayne Mullin. So the...
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Mullin under microscope by Senate colleagues over temperament, stolen valor and ICE in tense DHS confirmation hearing
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Delta CEO slams Washington over unpaid TSA agents, says front-line workers are being used as ‘political chips’
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Apple CEO Tim Cook doubles down on policy over politics while aligning with Trump’s manufacturing push
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'The Pitt' and a science show from Jimmy Kimmel get film tax credits
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Rand Paul confronts Markwayne Mullin over past rhetoric at Senate hearing
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Grassroots Climate Justice in Lebanon: Money, Power, and the Politics of Survival
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Tiger Woods provides health update as he eyes return at The Masters
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Pittsburgh Pirates vs. Athletics - Live Score
View the Pittsburgh Pirates vs. Athletics game played on June 15, 2026. Box score, stats, play-by-play timeline, highlights, odds & more
NJGOP Calls on Congressional Democrats to End DHS Shutdown, Stop Playing Politics with National Security
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Hail Yeah! NASA Researchers Use Volunteer Observations for Hail Estimates
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The scientist who warned that profit, not science, decides which drugs reach patients
In a Genomic Press Interview published in Brain Medicine, Dr. Gabriella Gobbi, Professor of Psychiatry at McGill University, Canada Research Chair (Tier 1) in Therapeutics for Mental Health, and President-Elect of the Collegium Internationale of Neuropsychopharmacology (CINP), delivers a pointed warning: the greatest threat to drug discovery is not scientific failure but a financing system that abandons effective, affordable treatments whenever they cannot promise sufficient returns to investors. Across a career that began in central Italy and moved through Sardinia and Montreal, Dr. Gobbi has generated landmark research linking adolescent cannabis exposure to depression, identified novel melatonin receptor mechanisms in sleep and pain, and launched psychedelic neuroscience before it became fashionable. The interview reveals a scientist whose best questions have always begun at the bedside, and whose most urgent fears concern the structures that stand between discovery and patients.
'Empty refrigerators and eviction notices': TSA union leaders demand end to DHS shutdown
TSA workers in Atlanta face a mounting financial crisis as the Department of Homeland Security shutdown continues, with agents dealing with evictions and hardships.
Fired DHS chief Kristi Noem faces criminal referral from congressional Democrats
Democrats accuse Kristi Noem of making "demonstrably false" statements to Congress regarding DHS contracts and Corey Lewandowski, weeks after her ousting by President Trump.
Dem senators call to fund DHS after voting to block it 4 times amid shutdown fight
Government shutdown continues over Department of Homeland Security funding as Democrats seek immigration enforcement reforms amid terror attacks.
Lee Health: Colorectal cancer awareness: Why screening matters
March is Colorectal Cancer Awareness Month — a timely opportunity to learn about colorectal cancer, understand your risk.
Still crazy: chaotic Six Nations showed the timeless appeal of great sporting drama
France’s dramatic triumph in the most extraordinary tournament was proof Test rugby played at full throttle ranks among the most compelling spectacles
Javier Bardem Condemns ‘Trump and Netanyahu’ for ‘Another Illegal War’ at a Very Political Oscars
Host Conan O'Brien was subtle with his comments, Jimmy Kimmel less so, and the nominated films themselves carried a political charge.
Oscars 2026 Politics: Winners, Presenters Slam Gun Violence, Trump, Wars
Javier Bardem, Jimmy Kimmel, Conan O’Brien and the winners in the documentary categories all used their time on stage Sunday to share some political commentary.
Jimmy Kimmel calls out CBS over free speech; swipe at Trump at Oscars
"Oh, man, is he going to be mad his wife wasn't nominated for this?" Jimmy Kimmel joked while presenting the award for best documentary feature.
'Heated Rivalry' actor says the show isn't political
"Heated Rivalry" actor Robbie G.K. spoke to NBC News’ Chloe Melas at Elton John’s Oscar party about how he disagrees with the show becoming political, adding that the show "explores human nature."
Dartmouth Health to open new addiction treatment center in Claremont
Dartmouth Health opens an outpatient addiction treatment center at Valley Regional Hospital in Claremont, providing convenient and timely care.
Scientists just discovered a tiny signal that volcanoes send before they erupt
A new detection method called “Jerk” could dramatically improve how scientists forecast volcanic eruptions. By using a single broadband seismometer, the system can detect extremely subtle ground movements caused by magma pushing underground—often hours before an eruption begins. Tested for more than a decade at the Piton de la Fournaise volcano on La Réunion, the tool successfully predicted 92% of eruptions between 2014 and 2023, sometimes giving up to eight hours of warning.
DeGette challenger Melat Kiros trounces 15-term Democratic incumbent in Denver delegate vote
The 28-year-old, first-time candidate challenging Democratic U.S. Rep. Diana DeGette in this year’s primary soundly defeated the 15-term incumbent in a delegate preference poll conducted Saturday at a county party assembly in Denver. Melat Kiros, the daughter of Ethiopian immigrants and a former corporate attorney, received nearly twice as many votes as DeGette in a […]
Markwayne Mullin, Trump’s Homeland Security Pick, Got Wealthier Stock Trading in Congress
Markwayne Mullin’s financial dealings take on new importance as the Senate considers his nomination to lead an agency whose budget has vastly expanded.
Colorado Rockies vs. Athletics - Live Score
View the Colorado Rockies vs. Athletics game played on June 12, 2026. Box score, stats, play-by-play timeline, highlights, odds & more
New Data Centers Will Be Powered by Human Brain Cells
Cortical Labs announced that it's working on "biological data centers" in Melbourne, Australia, and Singapore.
The day before the Oscars, the ‘Bridesmaids’ rehearsed
The “Bridesmaids” cast has reunited at the Dolby Theatre as Oscar presenters. On Saturday Kristen Wiig, Maya Rudolph, Ellie Kemper, Rose Byrne and Melissa McCarthy ran through their lines and
River Ryan impressing in spring after missing 2025 season
River Ryan is scheduled to pitch one of the Dodgers’ split squad games on Sunday, getting the home game at Camelback Ranch against the Texas Rangers. The right-hander who had Tommy John surgery in August 2024 and missed all of 2025, is now vying for a spot in the Dodgers’ rotation, or at least a […]
Linux Finally Catches Up to Windows with a Game-Changing Performance Feature
For years, the Linux kernel’s scheduler has been world‑class at balancing loads, yet it missed a crucial, cache‑aware instinct. In modern multi‑core systems, that gap can turn into measurable latency, especially when threads bounce between cores that don’t share the same cache. A new upstream feature, often called Cache Aware Scheduling, is now set to change that equation. A cache‑savvy scheduler arrives At the heart of any OS, the scheduler decides which thread runs where and for how long. In modern CPUs, small private caches (L1 and L2) sit beside each core, while a larger Last Level Cache (LLC, typically L3) is shared among groups of cores. When a task migrates across LLC boundaries, its warm data may vanish from the cache, forcing slower trips to main memory. Cache Aware Scheduling keeps related tasks close to their shared LLC, reducing destructive migrations. By respecting cache topology, the kernel minimizes cold‑start penalties and preserves locality that many workloads desperately need. The result is less thrashing, fewer memory stalls, and more consistent throughput. "Keep tasks close to their data, and the system will keep performance close to its peak." Why this narrows the Windows gap Windows has long leaned on topology‑aware, cache‑sensitive heuristics, especially since the Windows 10 era. That advantage helped Microsoft handle hybrid designs with P‑cores and E‑cores, plus complex cluster and NUMA layouts. With cache awareness integrated upstream, Linux brings parity to this vital dimension, without sacrificing its trademark flexibility. The Linux approach remains deeply configurable, reflecting the ecosystem’s breadth across servers, desktops, and embedded devices. It layers atop existing NUMA‑balancing and energy‑aware logic, refining placement rather than reinventing the wheel. Crucially, it aligns scheduling with the hardware’s real shape, not just with abstract CPU counts. Real‑world gains and who benefits Early tests on Intel Sapphire Rapids platforms point to gains in the 30–45% range for select workloads. Those wins appear in cache‑sensitive tasks like in‑memory analytics, high‑thread compilation, and microservices with tight working‑sets. Games and latency‑bound engines can also feel steadier frame‑times, especially when threads share hot assets. The benefits extend to AMD’s 3D V‑Cache parts, where keeping threads near enlarged cache slices prevents needless misses. Hybrid x86 designs with performance and efficiency cores further profit when cache and core roles are scheduled in concert. Even handhelds running SteamOS can squeeze more out of limited power, translating cache locality into smoother play. Key advantages include: Lower end‑to‑end latency Fewer expensive misses to RAM Better multi‑socket and NUMA behavior Improved energy efficiency More predictable QoS under mixed loads Stronger scaling on dense servers Caveats, tuning, and rollout No scheduler change is purely free, and trade‑offs still exist. Favoring locality can reduce cross‑cluster balance if limits are set too tight. Likewise, fairness and utilization must remain healthy, especially under heterogeneous, bursty workloads. Linux’s implementation is designed to be measured and tunable, not a blunt instrument. It cooperates with energy‑aware scheduling for mobile efficiency, and with NUMA‑balancers on big iron. Expect architecture‑specific refinements as vendors surface richer topology hints and cache‑sharing maps. Upstream integration has begun, with broad distribution adoption likely over the next cycles. Many users will encounter the change through standard kernel updates in 2025–2026, depending on distro cadence. Server‑class kernels may enable or tune it sooner for targeted fleets where cache locality is money in the bank. How to think about performance impact Cache Aware Scheduling amplifies gains when your workload is both CPU‑bound and cache‑sensitive. Think tight inner loops, hot code paths, and datasets that fit snugly in shared LLC. It’s less dramatic for I/O‑bound services or memory‑hungry tasks that blow past cache capacity. Still, even modest locality improvements often translate into smoother tail‑latency, which is where user experience and SLAs typically break. Developers can further help by pinning related threads, batching work, and aligning data to reduce cross‑cluster chatter. The scheduler’s new awareness works best when applications expose good hints. The bottom line By understanding and honoring cache topology, Linux removes a subtle yet costly bottleneck. The kernel’s smarter placement keeps hot data hot and work near where it belongs. That narrows a long‑standing gap with Windows, while preserving the openness and tunability Linux champions. For gamers, creators, and operators, the payoff is practical: more consistent frames, faster builds, and snappier services. For the ecosystem, it’s another step toward hardware‑savvy scheduling that turns transistor complexity into real‑world speed. And for Linux itself, it’s a timely upgrade that matches today’s silicon with tomorrow’s expectations.
Scientists discover giant swirling plumes hidden deep inside Greenland’s ice sheet
Scientists may have finally solved the mystery of strange plume-like structures hidden deep inside the Greenland ice sheet. New research suggests they form through thermal convection—slow, swirling motions driven by temperature differences inside the ice. This means the deep ice could be far softer than scientists once believed. Understanding this hidden movement could improve predictions about how Greenland’s ice sheet behaves in a warming world.
'Sinners,' 'Hamnet' And The Power Of Witchy Women In A Failing World
Wunmi Mosaku and Jessie Buckley's performances carry a deep and timely message.
Schefter: The Bears are broke (and what does that mean)
Adam Schefter says the Bears are broke. What does that mean? And will it limit what Ryan Poles and Ben Johnson can do to the roster?
Should the Pittsburgh Steelers close the door on Aaron Rodgers?
The NFL has had a busy week of transactions. Teams haven’t just signed free agents — they’ve also pulled off several trades. The Pittsburgh Steelers have stayed active on both fronts. They signed players such as Jamel Dean and Rico…
Researchers develop AI tool to predict patients at risk of intimate partner violence
NIH-funded, automated clinical decision support could facilitate timely interventions for at-risk patients years before they might otherwise seek help.
Ward Melville, Great Neck teams win LI Science Bowl
The contest tested teams' knowledge on science disciplines including biology, chemistry and physics.
The Rummel-John Curtis winner scored 13 runs and was sparked by a senior's 3-run homer
A senior third baseman's 3-run home run in the top of the first inning set the tone.
Senate Again Deadlocks on Homeland Security Funding as Shutdown Persists
The fight over restrictions on immigration agents has prolonged the funding lapse for T.S.A., Coast Guard and more into a second month, as airports experience screening delays.
Windows 11 gets extreme display refresh rate support and new features in KB5079387
A preview of this month's non-security update for Windows 11 is here, and it brings support for extremely high display refresh rates, improved File Explorer, and more.
Milwaukee Brewers vs. Athletics - Live Score
View the Milwaukee Brewers vs. Athletics game played on June 09, 2026. Box score, stats, play-by-play timeline, highlights, odds & more
Astronomers witness magnetar birth for first time
Scientists observed for more than 200 days the death of star that resulted in a dense, spinning remnant threaded with an extremely strong magnetic field
Are we still in a shutdown? Here's how DHS disruptions impact Americans
Here's why the U.S. Department of Homeland Security is shut down and what the partial closure means for Americans.
Tracie Thoms Joins Pamela Anderson, Billy Bob Thornton & Ariana Greenblatt In Brian Klugman Drama ‘Somedays’
EXCLUSIVE: Tracie Thoms (upcoming The Devil Wears Prada 2) has landed a role alongside Pamela Anderson, Billy Bob Thornton, and Ariana Greenblatt in Somedays, the new indie drama from writer-director ...
Maui’s Mental Health Crisis Goes Far Beyond the Wildfire Burn Zone
On the day of one of the deadliest natural disasters in Hawaii’s history, Blake Kekoa Ramelb watched his hometown go up in flames. It was Aug. 8, 2023, and Maui was burning. Ramelb, born and raised in Lahaina, lived outside the burn zone, so his home was intact. But he couldn’t get into town to […]
Hornets rally for 103-101 victory over the Trail Blazers
Brandon Miller had 21 points and eight rebounds, LaMelo Ball had 12 of his 14 points in the fourth quarter and the Charlotte Hornets overcame a 19-point deficit to beat the Portland Trail Blazers 103-101 on Tuesday night. Kon Knueppel added 15 points and five rebounds for the Hornets, who got back to . at 33-33.
Bondi reportedly moved to military housing because of threats
Other officials who have relocated include Secretary of State Marco Rubio; Kristi Noem, the exiting homeland security secretary; and Defense Secretary Pete Hegseth.
LA County sees drop in homeless deaths, the first in 10 years
While the news was welcomed by Los Angeles County supervisors and public health officials, they agreed that the mortality rate was still too high.
Arizona Is Now At the Center Of Election Investigations
Both the Department of Homeland Security and the FBI are probing the results of the 2020 election in Arizona.
Trump’s Shifting Timeline for How Long the Iran War Will Last
Now 11 days into an expanding military campaign, President Trump and his officials have given conflicting indications on when the United States intends to end the war.
Mental health solutions for the digital age
Ask the digital natives of Gen Z about the source of their biggest mental health challenges, and most will say social media and AI.Several of the nearly 400 guests at the third annual Gen Z Wellness Summit, presented by the Friends of Semel Teen Advisory Council at UCLA on March 8, explicitly named the endless stream of content on their phones as serious stressors. “Everybody is addicted to (Tik Tok) as if they were addicted to substances,” said Jantin Asmar, 17, a senior at Virtual Academy in Antelope Valley. “We’re always chasing that dopamine. We’re expecting that dopamine rush and it’s really decaying our interactions with others.” High school student Jantin Asmar was among nearly 400 people who attended the third annual Gen Z Wellness Summit. (Photo by Sandy Cohen) Even young teens feel pressure to be on social media constantly, both to consume content and collect “likes,” said 13-year-olds Chloe and Sophia, both students at Brentwood School. “Everyone’s always on, and you miss stuff if you’re not on it,” Chloe said, adding that social media’s emphasis on appearances is leading to eating disorders: “That’s a big thing for our generation.”The incessant influx of images and updates creates expectations that “weigh teenagers down,” said Linda Kou, 16, a junior at San Gabriel High School.Even though digital spaces allow people to connect with others beyond their immediate surroundings, it doesn’t always translate to real-life community, said Kelah Morgan, 17, a senior at Animo South Los Angeles Charter High School. High school students Kelah Morgan, left, and Linda Kou, shared about the challenges presented by social media. (Photo by Sandy Cohen) “Even if you see people saying that they relate to you online, it might be hard to find people in your personal life who you see every day who you feel comfortable enough to say, ‘You see me online, but this is me in real life and what I’m actually going through,’” she said.Solutions for our digital timesThe Gen Z Wellness Summit was intentionally designed as a free, in-person gathering where young people interested in mental health from across the southland could meet in person. “Peer support is the most important element of maintaining our mental health in community,” said Helena Hansen, MD, PhD, director of UCLA’s Semel Institute for Neuroscience and Human Behavior.Keynote speakers at the summit addressed AI, social connection and self-empowerment, while breakout sessions included discussions about eating disorders, dating, substance use, phone detox and breathwork. Here are some of the day’s top takeaways:Beware of FOPO: Scott Barry Kaufman, PhD, a psychology professor at Columbia University, said that rather than FOMO, or fear of missing out, we ought to be more aware of FOPO: fear of people’s opinions. “Just think about how much your FOPO might be holding you back in your life,” Dr. Kaufman said. “And just that inner contemplation should be enough for you to change your life, because there’s so many things we don’t go after because we have debilitating FOPO.”We don’t need to feel like we’re the best – or what he called “narcissistic self-esteem” – but it’s helpful to acknowledge our own worth, recognize our good qualities and develop self-belief in the skills and talents we’ve cultivated. When we have that – dignity and self-respect, without needing everyone to like us – FOPO is less of a concern.Self-reflection is most effective in community: “When we try to self-reflect alone, we sometimes ruminate,” said Ira Bedzow, PhD, executive director of the Emory University Purpose Project. “But when we self-reflect with people that we trust … (it) allows us to hold ourselves accountable to different ways of seeing and different ways of hearing and different ways of being.”Opening up about our experiences and listening to others are skills we can develop, Dr. Bedzow said.He invited students to participate in what he called a “fishbowl exercise,” where four students sat in a small circle, surrounded by a dozen or so students forming a larger circle. Those in the inner circle answered such questions as: “What stops you from being you today?” and “What helps you feel most like you?”Within minutes, the group in the small circle (the fishbowl), were sharing intimately about their life challenges as those in the outer circle nodded in understanding.After the exercise, one participant said, “I felt like I wasn’t alone, that it wasn’t just me who feels that way.”Another remarked on how “personal” it felt to share face-to-face with others, even strangers.Don’t let AI crush your creativity: Theoretical neuroscientist Vivienne Ming, PhD, has been studying artificial intelligence for more than 20 years. And while she said “it’s reasonable to be concerned” about the fast-growing technology, it can also help humans become better problem-solvers when used strategically.“The smartest thing on the planet today are humans and machines working together creatively,” Dr. Ming said. “What gets more valuable in humans as machines get smarter? Our ability to explore the unknown.“Your unique voice is literally your value to the world … but most of us for most of our lives have been taught to not be unique,” she continued. “Be your own person. Celebrate being different. It is genuinely, measurably, truly valuable.”In a breakout session called “Phone Detox? IYKYK: Living Your Story IRL” led by Don Grant, PhD, students shared their frustrations with AI compromising academic work, art and creativity.“Art is a translation of human experience,” one participant said. “When people use AI, they diminish their own human experience.”Dr. Grant urged them, as “the last generation to remember a world before AI,” to remember the power of imagination and creativity – and to act on it.Remember that social media distorts perceptions: Stuart B. Murray, PhD, PsyD, who directs the Eating Disorders Program and Translational Research in Eating Disorders Program at UCLA, asked the students in his breakout session to take a spontaneous selfie and edit it to conform with society’s beauty standards. All 20 girls in the room immediately got to work, thickening their hair, slimming their faces, plumping their lips.“The pressure to look like what we present on social media can be crippling,” Dr. Murray said. “We now know that social media use is part of a causal pathway into an eating disorder.”Adolescents and young adults are most at risk of developing an eating disorder, he said, with one in three students on college campuses exhibiting clinically meaningful eating-disorder symptoms. More than 4 million people in California will have an eating disorder in their lifetime.Even for those who don’t develop anorexia or bulimia, the ubiquity of modified images online distorts what we consider normal, making us feel worse about ourselves. Remembering that, he and other speakers said, might inspire us to log off occasionally and spend time in the real world with people who love us as we are.
Poe Hall employees had higher rates of cancer, federal health report says
On Monday, the National Institute for Occupational Safety and Health (NIOSH), a division of the CDC, found that employees inside NC State's Poe Hall had heightened rates of melanoma and possibly breast cancer.
Trump Advisers Urge Him to Find Iran Exit Ramp, Fearing Political Backlash
The president characterized the military mission as mostly having achieved its goals, but he didn’t provide a clear timeline for ending the Iran operation.
Human Brain Cells Run New Data Centers in Singapore, Melbourne
Biotech startup Cortical Labs is working on two small data centers run by human brain cells, putting lab-grown neurons onto silicon in an experiment that could one day challenge chips from the likes of Nvidia Corp.
Homeless man allegedly threatened Watertown business owner with knife
A homeless man is accused of threatening a Watertown business owner with a knife.
Reubin O’D. Askew Lecture Series returns with discussion on East Asia, the United States, and the Future of Democracy - University of West Florida Newsroom
The University of West Florida Askew Lecture Series returns to the Museum of Commerce in downtown Pensacola on Thursday, April 9, with a timely discussion on “East Asia, the United States, and the Future of Democracy.” This year’s event features Dr. Erik Mobrand, professor at the Graduate School of International Studies at Seoul National University […]
Report outlines premature deaths, chronic health problems among homeless Illinoisans
A volunteer with Street Samaritans hands out a care package to a person camping underneath a bridge in November in the Chicago area. (Medill Illinois News Bureau by Jacques Abou-Rizk)
How Markwayne Mullin Became Trump’s Homeland Security Pick
The Oklahoma senator whom President Trump chose to run the Department of Homeland Security has risen in Washington by styling himself as a MAGA warrior and Trump loyalist.
Trump’s Iran war drags the world into his tear-it-down politics
America’s attitude toward allies leading up to the Iran war was the geopolitical equivalent of a slogan on a jacket once notoriously sported by first lady Melania Trump: “I Really Don’t Care. Do U?”
Democrats make political bet on DHS demands, despite GOP’s Iran warnings
A week after President Trump launched strikes against Iran, Democrats are digging in against reopening the Department of Homeland Security (DHS) without significant reforms to the agency. Party le…