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Bausch Health’s $2B pursuit of Xifaxan successor hits wall with phase 3 failure
A potential inflection point that Bausch Health hoped could diversify its portfolio has vanished with a pair of phase 3 failures for a new formulation of the company’s bread-and-butter Xifaxan—a se | A potential inflection point that Bausch Health hoped could diversify its portfolio has vanished with a pair of phase 3 failures for a new formulation of the company’s bread-and-butter Xifaxan—a setback that leaves a $2 billion hole in its growth plan.
Viral moments: What James Talarico and Jasmine Crockett both get about politics in 2026
The two hopefuls for the Democratic nomination for U.S. Senate have bolstered their careers and raised their profiles across YouTube, Instagram and other social media platforms.
5 New Orleans East candidates hope to replace Hughes in District 100
See who is in the running to represent New Orleans East in the Legislature.
'All a bit meh' - Hibs season threatening to fizzle out
Sitting fifth in the league with little prospect of catching the top three and out of the Scottish Cup after a dismal display in Dunfermline, this season is threatening to fizzle out for Hibernian. Roll back to the start of term and hopes were high as David Gray's side followed up a third-place finish with three thrilling European tussles, going toe-to-toe with Midtjylland, Partizan Belgrade and Legia Warsaw. Summer recruits Jamie McGrath and Josh Mulligan have brought energy to the midfield, Dan Barlaser offers composure and Miguel Chaiwa has shown glimpses of bustling promise.
iPhone 18 Rumored to Feature Much Brighter Display
Apple's iPhone 18 will feature a significantly brighter display, according to a Chinese leaker. In a new post on Weibo, the user known as "Instant Digital" said that Chinese supplier BOE has little hope of making panels for the iPhone 18 because Apple's brightness requirements for the next-generation device are unprecedentedly high. This suggests that the iPhone 18's display will see a considerable leap forward in terms of brightness.
Rehabilitation and Sports Therapy Services Expand With New Erie Site
The facility is designed to help patients recover from orthopedic injuries, joint replacements and sports-related conditions.
How Indy Ignite became 'part of the fabric' of pro sports in Indiana
Indy Ignite general manager and president, Mary Kay Huse, hopes to use the momentum from the Ignite’s first season to build the team’s brand in 2026.
House panel approves bill to expand James Uthmeier's power to target physicians
Democrats fear giving the Attorney General more power after the Hope Florida scandal.
Fight to protect transgender health care to be among new governor's first tests
Supporters of proposed state protections for transgender health care are hopeful the bill will become law under Gov.-elect Mikie Sherrill.
Polis’ removal of sex ed funding endangers LGBTQ+ youth
By Shara Smith At a time when the LGBTQ+ community is attacked by public policy driven by religious extremists, I am deeply concerned by the removal of funding in the governor’s budget for Colorado’s Comprehensive Human Sexuality Education (CCHSE) grant program. I hope Gov. Jared Polis and the Joint Budget Committee will recognize the program […]
A phone on SF's Valencia Street aims to address the political divide through conversation
A social experiment is underway on the streets of San Francisco, aimed at connecting a country that at times seems so far apart. It all starts with picking up the phone.
‘An antidote to hopelessness’: At MLK Jr. Day events across Boston, people call for action amid political turmoil
The work Martin Luther King Jr. fought for is being dismantled by the Trump administration, journalist Nikole Hannah-Jones said.
In absence of Special Election, HD 113 hopeful calls for candidate meetings on future policy
‘Our district will be grateful and the winner of the November election will be in a better position.’
Diving Deep: Keeping up with the mental health journey with OHA
We're two weeks into 2026 and hopefully you're still keeping up with your New Years resolutions.
Seattle Mariners have high hopes for reliever Jose Ferrer
General manager Justin Hollander detailed why the Seattle Mariners think their new bullpen piece can be "an elite reliever in the American League."
Leading at the Frontlines of Rural Healthcare
Subscribe on LinkedIn This story first appeared in Amy Weaver’s LinkedIn newsletter, Direct Relief: Hope Ahead. A new year invites reflection. What should we carry forward? What needs to chan…
'Cyberpunk 2077' VR Mod Taken Down Following Legal Complaint, But There May Still Be Hope
Luke Ross, the prolific VR modder, has been forced to remove his popular Cyberpunk 2077 VR mod, citing legal concerns from CD PROJEKT. The News Ross released word via his Patreon on Saturday that Cyberpunk 2077 developer CD Projekt had issued a DMCA takedown notice for the removal of the game’s unofficial VR mod—just one […]
Atlanta Hopes Injury-Riddled Pitching Staff Returns To Health
A healthy pitching staff should boost the Atlanta Braves back into contention.
After years of criticising Davos, Nigel Farage heads to Davos
Reform UK leader has decried ‘globalist’ event but this year hopes to meet Donald Trump for Greenland talks
Huskies Fail to Build on Momentum in Loss to Spartans
The Washington Huskies gave their fans a glimmer of hope with a moral victory against Michigan earlier in the week. They did not make good on that hope in the follow-up game against the Wolverines’ in-state rivals. The Dawgs played Sparty even for the first five minutes of the contest, but a 10-0 run gave […]
Golden Knights looking for encore performance against Predators
Hopefully, the Vegas Golden Knights do not need a repeat of last game’s dramatics.
Burnley analysis: Jubilant Clarets earn hard-fought point
As Anfield emptied out, the Burnley players and their travelling supporters celebrated jubilantly. West Ham's win at Spurs was bad news for the Clarets' slim survival hopes, but this result was a rare moment of joy in an otherwise tough season for Scott Parker's side. On another day, Burnley could have been three or four goals down by the time they scored, but they showed courage and took advantage of Liverpool's sloppiness.
Bears' surge has White Sox hopeful of their own 'good, better, best' era
CHICAGO -- Chicago Bears fandom might not reside at the top of Chris Getz’s sports list as both a Michigan native and a member of the Grosse Pointe South High School Hall of Fame. But in his role as White Sox general manager, Getz appreciates the fervor, frenzy and unabashed
SLO County charcuterie business to open first storefront location. Where?
The mother-and-daughter owners told The Tribune they hope to be able to collaborate with other local businesses and provide a gathering place for local community members.
New incubator intended to foster emerging businesses in Frederick
Frederick city and business officials hope a small space can help create big opportunities for emerging local businesses.
Djokovic targets elusive 25th Slam at age of 38
Novak Djokovic says the upcoming Australian Open is not "now or never" for his hopes of winning a standalone all-time record 25th Grand Slam title.
Pressure all on Aberdeen in cup, says Imrie
Dougie Imrie hopes his Raith Rovers side can benefit from the pressure on Aberdeen in Sunday's Scottish Cup tie, which is live on BBC One Scotland and iPlayer. "The pressure is all on Aberdeen," said Imrie. Imrie is also hopeful striker Lewis Vaughan could be fit in time for the trip to Pittodrie.
Michigan businesses emerge from a turbulent year with cautious hope
John Long, COO of the Southeast Michigan Chamber of Commerce, described the outlook for 2026 as one of "economic confusion."
Denver7 takes business owner's concerns on power outages to Xcel Energy leader
Xcel Energy hopes to have power restored by Friday night for most customers impacted by power shutoffs as business owners in Larimer County reported lost revenue.
Baptist Health unveils new training facility; hopes to prepare nurses, doctors for state’s growing healthcare demands
Baptist Health has unveiled its newest state of the art medical training facility, built to not only train new healthcare professionals, but also give veteran healthcare professionals hands-on training with newer medical technology and procedures.
Judge orders Anna’s Archive to delete scraped data; no one thinks it will comply
WorldCat operator hopes default judgment will convince web hosts to take action.
High schoolers compete at regional Business Professionals of America conference
The hope is to develop skills in potential future career fields, and to advance to the State Conference in Grand Rapids
Illinois Republican governor hopefuls target JB Pritzker as Rick Heidner apologizes for past Democratic donations
At a forum of Illinois Republicans running for governor, Rick Heidner tries to explain contributions to former Cook County State’s Attorney Kim Foxx and Chicago Mayor Brandon Johnson.
Lynchburg official on hopes for incoming Spanberger Administration for business policy
As the preparations continue, excitement is also rising for people in our area attending the festivities.
Why Jenrick’s Reform Defection Fractures UK Political Right
The dramatic sacking of a senior Conservative and his defection hours later to Nigel Farage's Reform UK all-but ended the chances of any deal to unite the British right, confirming the next general election as the most widely contested in decades. Some Tories had held out hopes they could forge a pact with the insurgent Reform party that has rapidly eclipsed them in voter affections. The fallout from leader Kemi Badenoch's shock decision to fire her rival Robert Jenrick on Thursday put that further from reach. Our UK Politics Reporter James Woolcock joined Caroline Hepker and Lizzy Burden on Bloomberg Radio to discuss. (Source: Bloomberg)
'There cannot be any consideration' Carrick stays on
Manchester United should not extend caretaker manager Michael Carrick beyond this season, says former United team-mate Gary Neville. "I hope he does really well," Neville told The Overlap. "There cannot be any consideration that Michael takes the job beyond this season, for Michael and for the club.
Patrick Mahomes hopes to be ready for Week 1 after torn ACL, wants Chiefs to get back to 'winning culture'
Football gossip: Abraham, Baleba, Mateta, Maguire, Senesi, Mainoo, Ceballos
Tammy Abraham could reunite with Aston Villa, Manchester United hope to sign Carlos Baleba in the summer, and Jean-Philippe Mateta is a target for Juventus.
FanDuel Sports Network offers new deals to nine MLB teams as Nationals ditch MASN
FanDuel Sports Network operator Main Street Sports hopes to tempt MLB franchises who ended contracts last week.
LBCC will soon offer its first bachelor’s degree, starting with library sciences
California cleared the way for community colleges to award four-year degrees, but the programs are still scarce. LBCC hopes to eventually offer more.
A mother and daughter received the same cancer diagnosis. Here's what happened.
Matching multiple myeloma diagnosis shocked a mother and daughter. But they refuse to give up hope.
The U-turns keep coming – but Starmer’s allies insist they’re his best hope of revival
Prime minister wants cabinet ministers to move on from policies that have tanked with voters
Unhoused women on Skid Row face dire health outcomes. This doctor wants to change that
Homeless women face unique health challenges with few dedicated resources. And as the number of women experiencing homelessness in Los Angeles continues to grow, Dr. Mary Marfisee hopes to bring them lifesaving resources.
No. 4 Michigan hopes for bounce-back effort at Washington
Michigan's dominating season includes 10 wins by 25 or more points, but now there is a blemish on the ledger.
ESPN 1000's Marc Silverman eviscerates Bulls voice Chuck Swirsky for criticizing Bears coach Ben Johnson
When asked Tuesday if he had heard what Silverman said, Swirsky replied, “I respect your question. I hope you respect my answer. No comment.” Silverman said he doesn't regret the rant.
Senators punt release of health package to end of January
A bipartisan group of senators had originally hoped to release a framework this week.
Rybak: Minnesota’s Business Community Targeted by ICE
A new year of hope turned dark in a matter of days.
Japan’s new PM Takaichi eyes parliament dissolution for snap polls: Report
Country's first female prime minister hopes a bigger majority will help her implement her political and fiscal agenda.
n Venezuela, Amnesty for Political Prisoners Stokes Hope and Frustration
Venezuela’s new leaders and President Trump have alluded to a major release of political prisoners, but the liberations have been slow to come.
Mary Peltola enters Alaska U.S. Senate race
The former congresswoman is challenging incumbent Republican Dan Sullivan. Nationally, Democrats have high hopes that she can flip the seat.
Mary Peltola Runs for Senate in Alaska, Lifting Democrats’ Hopes
The former congresswoman is the latest top-tier recruit for Democrats, who face a difficult Senate map this year as they try to retake control of the chamber.
Willgress hopes accident will not hamper title bid
Wayne Willgress fractured his shoulder and right hand in a work accident last year but hopes it will not stop him making an impact at the World Indoor Bowls event in his home county of Norfolk.
‘We have a mission in the US’: France star Ousmane Dembélé tells CNN Sports he’s targeting World Cup glory after huge 2025
Winners in 2018, runners-up in 2022 – will 2026 be France’s year to once again rule the roost on soccer’s biggest stage? Les Bleus star Ousmane Dembélé hopes so.
Fulham 3-1 Middlesbrough
A great first round win against a strong Championship side. We're still on this stunning run of form that we can hopefully bring into the Premier League and the next round of the FA Cup. Alan: Could have started with Tom Cairney because he ran the show when he came on.
BoA Parts Ways With SM Entertainment After 25 Years
Singer BoA is concluding her 25-year journey with her agency SM Entertainment. On January 12, SM Entertainment issued an official statement announcing, “After extensive and in-depth discussions with BoA, we have agreed to conclude our 25-year partnership as of December 31, 2025.” Read the full statement below: Hello, this is SM Entertainment. First, we would like to express our sincere gratitude to Jumping BoA (BoA's official fan club) and everyone who has always loved and supported artist BoA. After extensive and in-depth discussions with BoA, we have agreed to conclude our 25-year journey together as of December 31, 2025. Debuting in 2000 at the age of 13, BoA has, now past the 25th anniversary of her debut, been beloved by global music fans as an “icon of global expansion” who pioneered the Korean Wave across Asia and as the “Star of Asia,” and she has become a role model for countless junior artists driving the K-pop boom. As a trailblazer and pioneer, BoA’s journey has shone thanks to her relentless effort and passion, leaving brilliant achievements and unparalleled records. From her extraordinary debut that wrote a new chapter in Korean popular music history to her present growth as a No.1 artist and producer, we remember every moment, and it has been a true honor for our company to walk alongside her every step of the way. For 25 years, BoA has been, without question, the pride, joy, and symbol of SM. Although our exclusive contract is coming to an end, we will continue to support BoA as she fully demonstrates her capabilities in the new activities and challenges ahead, and we hope she will shine even brighter as the “Star of Asia.” We ask for your continued love and support for BoA as she embarks on this new chapter. We also support the future of Kwon BoA the person, beyond the artist, and sincerely wish her happiness. Thank you. The agency also released a tribute video commemorating BoA's 25-year long journey with SM. Watch the full video below: https://www.youtube.com/watch?v=wjLQFtT3dCk Following the announcement, BoA took to her Instagram to share her feelings as below: Having given and received without holding back, I leave without regrets.I’m grateful for the time we shared and will continue to support the ever-shining SM Entertainment. Thank you. https://www.instagram.com/p/DTZxmAeEk6f/?img_index=1 Wishing BoA all the best on her new journey! Source (1)
How Stranger Things could inspire a new generation of physicists
Scientists hope the Netflix hit will encourage more teenagers to study physics because it explores wormholes, string theory and parallel worlds
PS5's First Exclusive Of 2026 Flops With Critics
It looks like PlayStation 5’s first exclusive game of the year is not performing to the expectations its developer had hoped.
Leeds University moonsighting project unites science and religion
The project hopes to end 'moon wars' between Mosques across the UK.
Owners of Laurel business damaged in tornado hope to reopen soon
Owners of a Laurel business heavily damaged in Friday's tornado were assessing that damage and counting their lucky stars Saturday.
TCU hopes to spoil No. 1 Arizona's unbeaten streak
No. 1 Arizona will look to continue its best start in more than a decade as it faces TCU on Saturday afternoon in Fort Worth, Texas.
Exclusive | Carol Burnett hopes this classic project defines her 70-year legacy:...
Comment | In worrying times for politics and the environment, art can still provide hope
And the audience matters just as much as the artwork
Amazon Has Big Hopes for Wearable AI — Starting With This $50 Gadget
Several months after Amazon.com Inc. bought artificial intelligence hardware startup Bee, the company said it’s working to make its $50 always-listening wearable more proactive, and indicated a larger revamp is in store.
DR MARC SIEGEL: Medical miracle or modern science? Both can be signs of God at work
Modern medical breakthroughs save lives in ways that feel miraculous, showing how faith and science can work together as instruments of healing and hope.
Black Sports Moms is equipping, empowering parents and athletes
Andrea Odom doesn’t hesitate when asked what sparked the idea she now hopes becomes a movement. The moment arrived just before the 2023 Major League Baseball draft, as agents began recruiting her son, Dylan Campbell of the University of Texas, and it came with a hard lesson her family didn’t expect to learn. “We had […]
Hope For Health Care Bills to Continue on 'Bipartisan Path,' Says DelBene
Democrat Representative from Washington Suzan DelBene, who also serves as the chair of the DCCC, says that the vote on an extension of ACA subsidies in the house is an 'important step forward' to push the Senate to make a deal on health care, even if this bill never becomes law. (Source: Bloomberg)
After shaky years, Mass. life science companies find glimmers of hope
After holding its breath for several rough years, Greater Boston’s life sciences sector is cautiously coming up for air.
Intel hopes its new chip can be the future of AI. An executive explains how
Once the dominant player in chips, Intel has struggled to keep pace with rivals over the past decade. An executive discussed the company’s AI strategy and future direction, driven by the launch of its new Core Ultra 3 chips.
Manchester United: Who are Darren Fletcher's son's Tyler and Jack?
BBC Sport profiles twin brothers Tyler and Jack Fletcher, who will hope to get minutes at Manchester United under interim head coach and father Darren
Personnel note: EDGE Communications promotes David Cruz Ramos to Chief of Staff
'David is the kind of leader every candidate hopes for: steady, strategic, and relentless in his pursuit of excellence.'
‘A unique moment for Minnesota’: Dems await Klobuchar’s future move
Sen. Amy Klobuchar has been the one constant in Minnesota politics for two decades. Democrats hope she can help save them.
Jefferson Health Among the Nation’s Top 100 Orthopedic Programs for 2025
Becker’s Hospital Review recognizes Jefferson Health as one of the best hospitals and health systems for orthopedic care
The Science of Hope: The Miami Project to Cure Paralysis Open House
The 10th annual open house invited people living with paralysis to learn about the Miami Project's spinal cord injury research.
Joe Starkey: Suddenly, there is joy and hope in the Pittsburgh sports world
Savor the moment. Things change fast in pro sports. But right now? On Monday, Jan. 5, 2026? This feels about as giddy and hopeful as it’s been around...
From tourism to wine, Syrian businesses flounder in post-Assad cultural flux
Shop owners report fewer travellers while bars and wineries hope for legal clarity on alcohol sale
In effort to remain open, downtown business transitioning to nonprofit
A small business in downtown Springfield is struggling to remain open but hopes by changing its structure it can do just that.
Jersey Bulls keep play-off hopes alive after Merstham win
Jersey Bulls boss Elliot Powell says they kept alive Isthmian League South East play-off hopes by beating Merstham 2-0.
West Hartford Business Buzz: January 5, 2026 - We-Ha
A round-up of openings, closings, and other news about West Hartford businesses. Business Buzz is sponsored by NBT Bank, and we are very thankful for their support! By Ronni Newton Happy New Year to all! I hope everyone had a wonderful holiday season and is (maybe) ready to get back to a
Yomiuri: Fujitsu CEO Hopes to See Defense Business Playing Role in Intl Security
Fujitsu Ltd. CEO Takahito Tokita expressed enthusiasm for expanding the company's defense-related business, saying, "We are very pleased to have the opportunity to contribute to the security of Japan and the world," during an interview with The Yomiuri Shimbun.
Businesses helping businesses: Local BBQ business steps in after smoker breaks down
Both owners hope the experience serves as a reminder that lending a helping hand, especially during tough moments, can make a difference.
Some thoughts on hope as a new year arrives
Discover pearls of wisdom from award-winning author Essie Chambers on the power of hope and perseverance.
Economic, business and technological predictions for 2026: Michael Weidokal
2026 will be another crucial year for our Northeast Ohio region, our country and the world. While there is a great deal of trepidation entering 2026 (with good reason), there are also many reasons to hope that this can be a year in which we reduce the level of political and economic risk in the world. Hopefully, our political and business leaders will work together to tackle the challenges we will inevitably face in 2026, and to take advantage of the opportunities that the new year will bring, writes guest columnist Michael Weidokal.
KMT chair hopes to take peace message to Beijing while on political tightrope
Bucs beat Panthers to keep NFL playoff hopes alive
Baker Mayfield and the Tampa Bay Buccaneers held off Carolina 16-14 on Saturday to keep their playoff hopes alive to the bitter end of the NFL season.But the Buccaneers held on.
Saturday Night Open Thread & NFL games: Hope for tomorrow
Come and join this merry band of Steelers’ faithful for some lively debate about our Steelers, good food, music, and the merits of the odd cold beverage.
Tim Walz was a Democratic hopeful. Now, he’s a Republican punching bag.
The Minnesota governor is seeking a third term amid a welfare probe in his state that has sparked unwanted national attention.
Knicks, smarting from ugly loss, pursue improvement vs. Sixers
Fresh off perhaps their most lethargic performance of the season, the New York Knicks hope to author a crisper effort Saturday when they host the Philadelphia 76ers.
At Zohran Mamdani’s block party, I observed a simple truth: people want more politics, not less
Years of scandal and disappointment have left a void in our politics. But New York’s new mayor offers an alternative to more apathy: hope, says author Samuel Earle
Steelers MVP ‘would love to come back’ in 2026
Kenneth Gainwell has enjoyed a breakout debut season with the Steelers and the fifth-year RB hopes to be back in Pittsburgh next year.
Good Sports: Fresno State swim ranked in top 25 for first time ever
This week, Fresno State swim is ranked in the top 25 for the first time ever. Looking ahead to the conference tournament and hopefully the big stage, the 'Dogs aren't slowing down.
Saints-Falcons Preview
ATLANTA (AP) The Atlanta Falcons and New Orleans Saints have similar goals of trying to complete lost seasons on high notes that offer hope that the momentum can carry over into next season.
Zohran Mamdani Supporters Celebrate “Politics of Optimism” at His Inauguration
Tens of thousands of New Yorkers braved freezing temperatures and police barricades to be part of Zohran Mamdani’s inauguration as mayor on New Year’s Day. Democracy Now! spoke with many Mamdani supporters, including a high school student and Palestinian activist Mahmoud Khalil, about what the day represented to them, their hopes for the new administration and how it could set a model for progressives across the country. “Organized people will always be more powerful than organized money,” said Diana Moreno, a fellow democratic socialist who is running for Mamdani’s vacant seat in the New York State Assembly.
Brain organoids are helping researchers, but their use also creates unease
Pea-size clusters of human cells called brain organoids inspire both hope and fear. Experts are debating how scientists can responsibly use these bits of gray matter.
Heave and hope: How Ole Miss pulled off one of the wildest College Football Playoff wins ever
Mayor Zohran Mamdani doubles down in an unapologetically progressive inauguration
If there was any hope New York City Mayor Zohran Mamdani would inch towards the middle or appeal to moderate Democrats as he launched his administration, it vanished in the bitter January air that ushered in the start of his term.
Encouraging signs of political civility bring hope for 2026
Americans have reason to hope that our political culture can change.
Japan business chiefs hope for stronger yen as import costs rise
Keidanren leader, others anticipate wage hikes, moderate economic growth in 2026
Apple reportedly cuts production of Vision Pro headset after poor sales
Company had hoped the virtual reality device would herald a new era in ‘spatial computing’