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Zohran Mamdani to deliver a speech marking America’s 250th birthday

The New York City mayor will speak from George Washington’s desk hours before President Trump delivers a speech from Mount Rushmore.

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Jul 1 • 3:42 PM EDT • Politics • nbcnews.com
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Are your kids already bored this summer? Here’s a new entertainment option.

Sky Zone of Wichita is “an indoor trampoline amusement park,” as one of its owners put it, and is having a soft opening starting July 10.

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Jul 1 • 2:30 PM EDT • Entertainment • kansas.com
Mad Science: Fourth of July Experiments

Mad Science's Radiant Randy joins Shane and Kerrigan to share a few firework-inspired experiments.

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Jul 1 • 2:23 PM EDT • Science • kctv5.com
A Colorado primary defeat highlights a dangerous political environment for Democratic incumbents

Democratic socialist Melat Kiros defeated Rep. Diana DeGette in Denver on Tuesday night, the latest in a string of results heralding big change for the party in Washington.

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Jul 1 • 12:57 PM EDT • Politics • nbcnews.com
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Google Gemini Spark Comes to Mac With Local File Automation

Google today launched Gemini Spark for its macOS desktop app, allowing the AI agent to automate tasks involving local files and desktop workflows. Google announced the update today, adding a dedicated Spark tab to the sidebar of the Gemini app for macOS. The feature allows the AI agent to take action on files stored locally on a user's computer rather than just responding to questions in a chat window.

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Jul 1 • 12:10 PM EDT • Technology • macrumors.com
From The Sports Desk: Mexico’s first knockout win in four decades

Mexico won a knockout game for the first time since 1986 when it beat Ecuador 2-0 yesterday. Elsewhere, Norway beat Ivory Coast 2-1, and France hammered Sweden 3-0.

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Jul 1 • 11:10 AM EDT • Sports • nbcnews.com
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There’s already a history with both Miami and …

There’s already a history with both Miami and …

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Jul 1 • 8:37 AM EDT • Sports • sports.yahoo.com
Sony will cease production of discs for new PlayStation games in 2028

New games sold for PlayStation consoles will only be available digitally and won’t be sold on discs effective January 2028, Sony has announced. The move applies to all PlayStation games released from that point on, including those made by Sony and those released by third parties. The PlayStation group calls the change “a natural direction for Sony Interactive Entertainment to adapt to consumer trends as the general preference for digital media significantly outpaces physical discs,” according to a PlayStation blog post reviewed by Game File in advance of its publication. As movies, TV and music have shifted from physical media to an age of downloads and streaming, Sony’s move could speed the demise of physical media in a gaming. The industry has offered consumers games via cartridges, cassettes, floppy discs, CDs, DVDs and Blu-Rays across a 50-year stretch. Sony has been reporting to investors in recent years that PlayStation games have been increasingly purchased as downloads, not as discs. The most recent figures show nearly four in five purchases of full games for PlayStation 4 and PlayStation 5 were purchased digitally in the past year. Stats like that may cause today’s news to carry an air of the inevitable. But Sony’s declaration for 2028 is still likely to produce a shock, as the biggest gaming platform on the planet that uses game discs leaves them behind. Discs going away, but the fate of game boxes is unknown Sony is committing to still selling games in physical retailers even after they drop discs in 2028. Just how those games will be sold—in boxes with codes inside, as cards marked with digital redemption codes—is unclear. Digital games will also continue to be sold in the online PlayStation Store. New games released for PlayStation consoles prior to January 2028 will be unaffected by the policy change, Sony says. That means the PS5 games of 2027, be they a new Madden, a new God of War, a new Call of Duty, a new Sly Cooper (one can dream?), would still potentially be offered on disc. PlayStation 6 implications Sony’s timeline for a transition to a no-disc era will also spin up more speculation about the timing and configuration of Sony’s next-generation console, the probable PlayStation 6. “This pretty much guarantees that PS6 won’t arrive until 2028 at the earliest,” Piers Harding-Rolls, senior games research analyst at Ampere Analysis tells Game File. Harding-Rolls also concludes from today’s news that “the base version of a PS6 will not include a physical media drive,” as Sony looks to keep costs down on the device. Sony itself is saying nothing about the PS6 today: not its timing, nor how it might or might not support internal or external disc drives in order to run disc-based PS4 and PS5 games, should the console be backwards compatible. The many signs this was coming Industry support for games being released on physical media has been waning. As has consumer interest in them. PC games effectively went all-digital years ago, thanks to the popularity of playing games through Steam and other digital storefronts. The Covid-19 pandemic and the lockdowns that kept much of the global population home helped shift shopping patterns toward downloads. Sony’s own data shows PlayStation game downloads being an uncommon consumer choice a decade ago and now becoming the norm. On consoles, physical media has been in such decline that Sony and Microsoft both launched their current gen Xbox Series and PS5 consoles in 2020 with cheaper versions that lacked disc drives. In early 2024, Phil Spencer, then head of Xbox, told me that ““[w]e ship games physically and digitally, and we’re really just following what the customers are doing.” He added that the game industry had become an outlier in still supporting disc-based entertainment, even as movies and TV have bailed on discs in favor of downloads and steaming: “Gaming consoles themselves have kind of become the last consumer electronic device that has a drive. And this is a real issue, just in terms of the number of manufacturers that are actually building drives and the cost associated with those. And when you think about cogs that we’re going to go put in a console—and as you have fewer suppliers and fewer buyers—the cost of the drive does have an impact.” Last year, the Nintendo’s Switch 2, which uses cartridges rather than discs, introduced the concept of game-key cards, which are physical media that contain no game, just a prompt for a download. Even disc-based games aren’t what they once were, now frequently containing just stubs of games rather than the whole thing. The website Does It Play has tested over 3000 games and found that, for example, that the disc version of this year’s hit 007: First Light, only contained the game’s first mission, with the rest needing to be downloaded. Beyond all that, last week brought the news that Grand Theft Auto VI, likely the biggest game launch this decade, will debut for PS5 and Xbox Series without a disc-based version. Today’s big news comes to you for free. Game File is a reader-supported publication. To receive new posts and ensure more of my work is possible, please consider becoming a free or paid subscriber. Subscribe Discs helped define PlayStation However the trends in entertainment may be going, it is still remarkable to see PlayStation ditch discs given their importance in PlayStation history: In the late 1990s, the first PlayStation’s support for games on relatively cheap CD-ROMs instead of traditional game cartridges allowed the upstart console to outmaneuver cartridge-based systems from Nintendo and Sega, as it drove down game prices down in the process. (The cheaper disc format even prompted Final Fantasy VII maker Square to taunt Nintendo in a magazine ad, saying that if the game was “available on cartridge, it’d retail for around $1200.”) PlayStation devices often doubled as machines for watching movies and TV on the latest disc-based formats. In the late 2000s, for example, Sony’s pricy PS3 gained traction as a go-to device for playing then-novel Blu-Ray discs. In 2013, Sony effectively roasted the digital game-sharing restrictions proposed by rival Microsoft for its upcoming Xbox One console by showing how games could be shared for the then-upcoming PS4. In a 21-second clip that has over 20 million views on YouTube, one PlayStation executive simply handed a game box—presumably with disc inside—to another, who said “thanks.” Sony’s possible motivations The PlayStation announcement today cites “consumer preferences” and a shift away from discs among “the broader entertainment industry,” but does not delve into the decision-making process that brought Sony to this point. Sony is not discussing the economics of this move (I asked!), but there are a number of potential factors: Abandoning discs will spare Sony the cost of manufacturing and shipping them, which analysts and industry veterans I spoke to said could account for $1 or so of a game’s retail price. For first-party games, that’s direct savings for Sony, though the amount is limited by the winnowing percentage of people who were even buying the disc-based versions. For third-party games, Sony could pass the savings on to partners or just retain the better profit margin for themselves. As the 2024 comments from Phil Spencer alluded to, leaving discs behind could mean leaving disc-drives behind, allowing Sony to produce consoles more cheaply. Switching to digital-only for games could diminish the risks of copies of new games leaking. It would also seemingly make second-hand sales of used games impossible, pushing more people to buy their own copies of games. These economic benefits for Sony could be boons for the games industry overall, Ampere analyst Piers Harding-Rolls tells Game File. Among other things, it could free publishers and retailers from having to worry about securing an inventory of game discs when trying to sell games, he noted. “If there is a way to streamline the business of games retail, I generally think it’s a good thing for the industry as it removes unnecessary costs,” Harding-Rolls said. “This will help offset pressure on margins from other directions – development and staffing costs for example.” Should the industry shift from game boxes that contain discs to smaller, cheaper game cards, Harding-Rolls said, that reduces pressure on publishers and retailers. “The advantage of everything going digital for the industry is that sales can be tracked much more easily and there is less commercial risk for publishers wanting to continue selling via retail,” he said. The shift to no discs will also likely impact game development timelines, as developers will no longer face the same urgency to have a build ready to submit to PlayStation for the production of a disc, as industry experts noted around GTA VI’s no-disc news last week. Instead, projects may gain weeks of development time, in the event delivery deadlines for platform approval move closer to release date. Preservationists’ likely worries While millions of gamers have shifted to digital, there are still people who associate game discs—and only game discs—with actual ownership of PlayStation games. That portion of the gaming community spoke up last week about wanting to buy a version of GTA VI that they could hold in their hands, could lend to a friend and could potentially pop into a well-preserved PS5 console three decades from now and still see it run. Such gamers didn’t want to worry that they’d merely purchased a digital copy that could lose access to the game if, say, the company behind the game someday turns of the servers that transmit downloadable copies. Digital copies of games are inherently less long-lasting, because consumers aren’t actually buying a game (on a disc), just buying access to the game. The fine print in online gaming shops notes this, as does a recent law that went on the books in California in 2025. That lasw requires game publishers doing business in the state to refrain from words like “sell” when offering digital copies of games, unless they explicitly tell consumers that what’s being sold isn’t the game itself but a potentially revocable license to access it. A Sony spokesperson noted to Game File that “[w]ith all digital content, including games, movies, and music, players are purchasing a personal license for non-commercial use.” Regarding the fears of PlayStation games being lost to time in an all-digital era, the rep also noted that Sony remains “committed to delivering experiences from past generations to the new platforms our players are using.” They noted that PlayStation has used emulation and remasters to keep offering its classic games to modern gamers. It’s true that many consumers have become accustomed to not having physical copies of new music albums or movies, but the relative precariousness of digital copies of games is in fact being highlighted today by…. Sony’s other big announcement: the upcoming closure of the PS3 and PS Vita online stores Sony said today that it will be closing the online marketplaces for its PlayStation 3 console and PS Vita handheld in most countries in July 2027 (sooner elsewhere: August 2026 for the PS3 store Mexico, Honduras and Nicaragua; late 2026 for PS3 in other Latin American countries and the Middle East). “We know this news may be disappointing to PS3 and PS Vita players who hold a special place in their hearts for this generation of gaming,” Sony said in its announcement, saying the move “was not an easy decision for us to make.” Sony said that PS3 and Vita marketplaces “are no longer able” to support modern commerce systems, prompting a “need” to close the shops and focus on more modern PlayStation platform stores. The news may spark some deja vu. Sony announced back in March 2021 that it planned to take the PS3, Vita and PlayStation Portable marketplaces offline that summer. The move would have caused some 2,000 digital-only games to become unavailable for new purchasers, according to a VGC analysis at the time. Fans complained loudly. By April 2021, Sony walked back the PS3 and Vita shop closures, with then PlayStation boss Jim Ryan saying “it’s clear that we made the wrong decision here.” This time around, Sony is giving a longer notice period in most regions. The closure of those stores is still likely to cut off access to new purchases of digital-only PS3 and Vita games. The current PlayStation 5 marketplace sells PS5 and PS4 games, as well as a selection of PS1 and PS2 games. It does not sell PS3 games, because games for that platform can’t run on the system (some are offered via a PlayStation Plus streaming option). Vita games also aren’t sold via PS5. Sony says digitally purchased PS3 and Vita games will be downloadable after the stores’ shutdowns “for the foreseeable future.” Sony’s move contrasts with Microsoft’s Xbox platform, which continues to sell and support games from all four Xbox console generations. But it puts it in line with Nintendo, which disabled purchases in the marketplace for its Wii console (a contemporary of the PS3) in 2019. Nintendo discontinued purchases in the online shop for its 3DS portable (a contemporary of the Vita) in 2023. The big questions about Sony’s 2028 post-disc era Will Microsoft follow suit, ending support for new disc-based games on Xbox platforms and therefore all game consoles, too? Whether Microsoft does or not, will third-parties that can no longer release games on discs for PlayStation, simply ditch the disc options across the board? Given the GTA VI no-disc experiment launching this November, will more game publishers decide to forgo disc-based offerings even in 2027? How will no-disc PS5/6 games be packaged and sold in brick-and-mortar retail stores? What becomes of game sharing in an all-digital era? Will Sony modify its current set-up, which currently allows some sharing of digital games across a pair of consoles, to allow more casual lending? (See for example, Nintendo’s year-old system of letting players lend a digital game to another player in a “family group” for up to 14 days.) Will there be a version of a PS6 with a disc drive? Or will a drive be offered as an add-on? And how will gamers who want to retain access to PS4/PS5 disc-based games react to whichever configurations Sony chooses to offer? What will the final disc-based PlayStation game be?

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Jul 1 • 8:00 AM EDT • Technology • gamefile.news
Danny Glover Reveals Alzheimer’s Diagnosis on TODAY: EXCLUSIVE

The 79-year-old “Lethal Weapon” star shared with Lester Holt that he was diagnosed with the progressive neurodegenerative disease a few years ago.

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Jul 1 • 7:43 AM EDT • Health • today.com
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Americans step out for their nation's 250th in a proud moment sown with division and doubt

America has come to a landmark moment of pride and patriotism — and a time of division and doubt

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Jul 1 • 6:48 AM EDT • Politics • washingtonpost.com
Steelers film study: Eli Heidenreich's playmaking skills need more seasoning

It wasn’t just a good story that led to Eli Heidenreich being a seventh-round selection in his hometown by his hometown team. The Pittsburgh native...

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Jul 1 • 6:00 AM EDT • Sports • post-gazette.com
Poll: Most Americans think the U.S. has strayed from its founding principles

Most Americans believe the country has moved away from its founding principles as the nation prepares for its big 250th anniversary, a new PBS News/NPR/Marist poll finds. Eighty-three percent of U.S. adults feel America has strayed from the ideals the country was founded on two-and-a-half centuries ago. Among them, close to half of Americans — 47% — say the U.S. has "moved far away" from these principles, joined by 36% who said America has “moved

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Jul 1 • 5:00 AM EDT • Politics • pbs.org
Weiser wins Colorado Democratic governor primary race over Bennet

NBC News projects that Weiser will move on to the general election after defeating Bennet, who has served in the Senate for 17 years.

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Jun 30 • 9:39 PM EDT • Politics • nbcnews.com
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What to watch for in Colorado tonight: From the Politics Desk

Plus, wrapping up a jam-packed final day of the Supreme Court’s term.

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Jun 30 • 5:45 PM EDT • Politics • nbcnews.com
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RFK Jr. wants to make it easier to get peptides. FDA scientists disagree.

The health secretary has advocated for deregulating certain peptides, but FDA scientists point to a lack of data about their safety and effectiveness. Some have not been studied in humans.

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Jun 30 • 3:36 PM EDT • Health • nbcnews.com
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Penguins trade Parker Wotherspoon after a breakout season in return for Vegas defenseman Kaedan Korczak

The Penguins made a surprising trade Tuesday, sending defenseman Parker Wotherspoon to the Vegas Golden Knights in exchange for defenseman Kaedan Korczak. Korczak,...

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Jun 30 • 2:50 PM EDT • Sports • post-gazette.com
GTA VI May Be Limited to 30 FPS on Current-Gen Consoles

With the launch of Grand Theft Auto VI rapidly approaching, rumors surrounding the game's launch have been circulating, with some of those predicting that the game's launch will result in a console hardware shortage, more recently, however, Digital Foundry predicted that the new GTA game may not be ...

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Jun 30 • 12:56 PM EDT • Technology • techpowerup.com
Conduent agrees to sell tolling business to Quarterhill for $70M

Conduent Inc. announced on June 30 that it has agreed to sell its tolling business to Toronto-based Quarterhill Inc.

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Jun 30 • 12:28 PM EDT • Business • roi-nj.com
7 things fantasy football players — and fans, too — should know about the Steelers’ offense

Believe it or not, Steelers training camp is only four weeks away. That means fantasy football season is right around the corner, too. One of the Post-Gazette’s...

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Jun 30 • 12:00 PM EDT • Sports • post-gazette.com
Jazz Under the Stars returns August 6

KCCK's Jazz Under The Stars celebrated the station's 50th anniversary last year by reuniting some of Iowa's best-known jazz, blues and R&B performers. Iowa's Jazz Station kicks off its second

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Jun 30 • 11:43 AM EDT • Entertainment • thegazette.com
World Cup results: Paraguay upsets Germany on penalties; Brazil beats Japan

There are three more knockout matches today.

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Jun 30 • 11:13 AM EDT • Sports • nbcnews.com
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Supreme Court rejects Trump attempt to limit birthright citizenship

The Trump administration sought to upend the historical understanding of the 14th Amendment, which has long been interpreted to extend birthright citizenship broadly.

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Jun 30 • 10:36 AM EDT • Politics • nbcnews.com
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Supreme Court strikes down long-standing campaign finance restrictions

The provision challenged by Vice President JD Vance and others limits how much party committees can spend in coordination with individual candidates.

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Jun 30 • 10:28 AM EDT • Politics • nbcnews.com
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Supreme Court upholds state transgender sports bans

In the latest of a string of losses for LGBTQ rights, the high court allowed states to bar transgender athletes from girls’ and women’s sports.

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Jun 30 • 10:04 AM EDT • Sports • nbcnews.com
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Alan Ritchson's 'Reacher' sets season 4 premiere date a month ahead of 'Neagley' spinoff debut

'Reacher's series is returning for its fourth season this summer, just in time to usher in the premiere of its Maria Sten-led spinoff series.

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Jun 30 • 10:00 AM EDT • Entertainment • ew.com
‘A place where everyone felt welcome,’ New KC business offers sensory-friendly play for kids with autism

Bubbles and Goo opened in Kansas City's River Market to offer sensory-friendly slime play for families affected by autism.

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Jun 30 • 9:59 AM EDT • Business • kshb.com
Crews called to overnight fire to auto repair business in Boonville

We’re told there was damage to the back corner of the business.

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Jun 30 • 8:51 AM EDT • Business • 14news.com
Alleged iPhone 18 Pro Sim Tray Again Shows Dark Cherry Color

Apple's upcoming iPhone 18 Pro models are expected to introduce new color options, including a dark cherry color, and today we may have been given another peek at the rumored finish, courtesy of the Chinese leaker known as Ice Universe. Image shared by leaker Ice Universe In an image posted on Weibo, a SIM tray allegedly from the unreleased iPhone is shown in a dark cherry colour, which could also be described in this grainy example as burgundy, brownish, or purple.

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Jun 30 • 8:23 AM EDT • Technology • macrumors.com
The No. 1 Daily Exercise for a Strong Deep Core, According to a Trainer

In TODAY.com’s Expert Tip of the Day, a personal trainer and TODAY.com editor shares her top workout for strengthening the deepest muscles of the midsection.

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Jun 30 • 8:00 AM EDT • Technology • today.com
New BioShocking Attack Tricks AI Browsers Into Leaking User Credentials

LayerX says BioShocking used indirect prompt injection to trick six AI browsers into copying credentials from signed-in accounts.

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Jun 30 • 4:37 AM EDT • Technology • thehackernews.com
Lisa Cook’s attorney reacts to Supreme Court win
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Jun 29 • 9:27 PM EDT • Politics • cnn.com
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'Yellowstone' creator Taylor Sheridan slams Marvel movies and studio execs: 'It didn't used to be this way'

'Yellowstone' creator Taylor Sheridan had harsh criticism for Marvel movies, saying the superhero films use 'information dumps that you have to follow to get to the action rather than actually moving plot.'

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Jun 29 • 9:05 PM EDT • Entertainment • ew.com
KC council wants to crack down on unlicensed businesses that lead to violence

A city law change is being considered weeks after a shooting at an unregistered nightclub.

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Jun 29 • 7:23 PM EDT • Business • kansascity.com
Supreme Court hands Trump new power to tighten his grip on the federal government

Trump lost a Supreme Court case over his attempted Fed firing. But he won a bigger fight for presidential power.

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Jun 29 • 6:26 PM EDT • Politics • nbcnews.com
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Michigan’s Democratic Senate primary carries 2020 echoes: From the Politics Desk

Plus, Trump’s voting plans run into resistance.

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Jun 29 • 5:45 PM EDT • Politics • nbcnews.com
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Netflix and Superheroes Are Having a Rough Stretch on Streaming....

(Welcome to my weekly streaming ratings report, the single best guide to what’s popular in streaming TV and what isn’t. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. If you were forwarded this email, please subscribe to get these insights each week.) I have a quick prediction before we start today’s article: You might see this data in future news articles. Not my specific charts or analysis, but the core trend I’ve been monitoring—Netflix is having a lackluster Q2—will become inescapable. Often, folks want to know “What does the data say?” Well, that’s what it says. I haven’t seen this analysis hit the trades really yet, but I have a feeling some other outlets are going to start making this case soon. Remember, you read it here first. You probably have read about the problems facing superhero films at the box office this weekend. Well, this week, I explore whether superheroes are dying on TV as well! And the data says: definitely maybe! We have a lot to cover in today’s Streaming Ratings Report, which covers the two weeks of 18-May and 25-May. Today, I’m just looking at TV, like Netflix’s disappointing Q2, superhero shows underwhelming, a few TV shows dropping off the charts, The Pitt finally ending its epic run on the viewership charts (and whether “view counts” change its status as one of the biggest shows of all time), all the flops, bombs and misses, and a whole lot more. Tomorrow, I’ve got a great rundown of the film side of things. Let’s dive right in! (Reminder: The streaming ratings report focuses on the U.S. market and compiles data from Nielsen’s weekly top ten viewership ranks, Luminate’s Top Ten Data, Showlabs, TV Time trend data, Samba TV household viewership, company datecdotes, Netflix hours viewed data, Google Trends, and IMDb to determine the most popular content. While most data points are current, Nielsen’s data covers the weeks of May 18th to May 31st, 2026. You can find a link to my terminology here.) Subscribe Television - Netflix’s Q2 Slump Continues Having analyzed streaming ratings for going on half a decade, I have learned to trust my gut, but I’m always relieved when I can find actual data to back it up. For example, after a string of very popular shows like Stranger Things, Bridgerton, The Lincoln Lawyer and The Night Agent came out, week after week, in January and February, my gut wondered if Netflix had enough new and returning TV shows to sustain them throughout the year. Since then, Netflix’s post-March slate of shows has not impressed me. This week seemed to feature a potential new hit, but then, like a classic Duffer Bros. TV show, there was a twist. I speak of The Boroughs, Netflix’s latest (and last) Duffer Bros. produced show. The pitch is “Stranger Things with older actors”. And it topped the Nielsen charts: With just two weeks of viewership, The Boroughs would have been a top 25 debut show last year: But here’s the twist: Netflix has already cancelled The Boroughs! What happened? Likely a few things. First, the show didn’t do as well globally as it did in the US. As What’s on Netflix showed, it lagged behind several other shows that got cancelled. Second, its completion rate was likely low; after an initial burst of interest, it quickly dropped off on the Samba TV and Luminate charts. Third, the Duffer Bros. left Netflix for Paramount, and that may have factored into Netflix’s decision here. (Though I tend to believe that if a show is doing well, Netflix would have kept greenlighting seasons.) Still, just because I can explain why Netflix may have cancelled this show doesn’t mean I’m justifying it. In particular, as I’ve noted before, Netflix is losing a lot of their bigger shows as they reach their natural ends, and they need to replace those shows. This show had the hallmarks of a big new genre show, and it’s their biggest hit of the last few months (in the US at least), but now it’s done. Netflix’s other show this week—The Four Seasons, the second season of the “hit” show from last year—definitely disappointed. Its sophomore season had about half the viewership of the first, only 12.7 million hours. It also only had a two week run on Samba TV, and its numbers were all down on Luminate too. In other words, even with two successes, the Q2 slump for Netflix looks real: I could add to the list of disappointments: Both Lord of the Files and Man on Fire had short runs on the Nielsen charts. Running Point’s sophomore season also opened to about half its viewership, similar to The Four Seasons. A Good Girl’s Guide to Murder’s second season—see below—didn’t even make any of the three viewership charts I track, unlike the first season. Netflix is absolutely having a dismal second three months of 2026. If this Nielsen data is any indication, and I think it is, I think this will show up in Netflix’s engagement report, and maybe even their financial outcomes. And the rest of June doesn’t look much better. We have two hit shows coming back—Sweet Magnolias, one of their quietest big shows, and Avatar: The Last Airbender, a big hit for them in 2024—but the other big swings are limited series crime thrillers i.e. no future season potential. Like I said above, sometimes when I uncover a juicy nugget like this, other outlets end up writing very similar articles mimicking the data without credit. We’ll see if that happens this time! Share Television - The State of Superhero Shows on Streaming When I first heard the pitch for Spider-Noir—a Sony TV show on Prime Video that binge-released eight episodes first on MGM+ then on Prime Video two days later—I had my doubts. It’s a live-action Spider-Man show set in the 1930s, starring Nicholas Cage, based on a cameo of a character in Spider-Man: Into the Spider-Verse. No, seriously, that’s the pitch. That could either go terrifically well or horribly wrong. Great because, Spider-Man. He’s the biggest superhero we have. I’ve seen tracking numbers that put the new _Spider-Man: Brand New Da_y as the blockbuster of the year and initial pre-sales back that up. And yet this Spider-Noir pitch feels very esoteric. (Also, the eight-episode binge release feels very “Amazon copying Netflix” again.) So what’s the data say? And what does this say about the future of superhero shows?

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Jun 29 • 5:43 PM EDT • Entertainment • entertainment.substack.com
Israeli strikes kill at least 8 in Gaza, including 2 children, health officials say

While the heaviest fighting has subsided since a ceasefire took hold in October, Israeli forces have carried out near-daily strikes, killing 1,045 Palestinians, including more than 360 women and children, according to health officials in Gaza.

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Jun 29 • 5:18 PM EDT • Health • nbcnews.com
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A Diet and Workout Plan to Hit Weight-Loss Goals By the End of 2026

A dietitian and personal trainer share the simple plan they give clients who want to lose weight, build strength and feel more energized by the end of the year.

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Jun 29 • 2:08 PM EDT • Health • today.com
Eskin named general manager of NEXUS sports and entertainment complex

Middlesex County, in partnership with The Sports Facilities Companies, announced Edison native Katie Eskin as General Manager of NEXUS.

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Jun 29 • 1:00 PM EDT • Entertainment • roi-nj.com
Cook County Issues New Funding Opportunities to Improve Mental Health in Suburban Cook County - Cook County Department of Public Health

Cook County Department of Public Health has issued an open call for funding opportunities to help improve mental health in suburban Cook County. The funding opportunities reflect the department’s commitment to building healthier communities in suburban Cook County. The open calls are for restorative practices in schools and power building.

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Jun 29 • 11:43 AM EDT • Health • cookcountypublichealth.org
From The Sports Desk: Canada beats South Africa in World Cup knockout: Brazil vs. Japan preview

The knockout rounds of the World Cup began with a late winner from Canada as three more matches take place today.

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Jun 29 • 11:10 AM EDT • Sports • nbcnews.com
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The Fleet Science Center just got a major upgrade

There are more interactive exhibits, a free entry gallery and a new cafe.

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Jun 29 • 9:15 AM EDT • Science • axios.com
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Dietitians on Healthy Food Pairings To Absorb More Vitamins and Nutrients

In TODAY.com’s Expert Tip of the Day, dietitians share their favorite strategic food pairings to help your body absorb more nutrients.

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Jun 29 • 8:00 AM EDT • Health • today.com
Comcast to split into two companies, spin off NBCUniversal and Sky

The move announced Monday will separate Comcast’s media and entertainment assets from its broadband and wireless business.

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Jun 29 • 6:22 AM EDT • Business • nbcnews.com
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How an under-the-radar GOP official is shaping local voting plans in North Carolina

After Republicans shifted key election authorities to State Auditor Dave Boliek, Democrats and voting rights activists have criticized his involvement in early voting site discussions.

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Jun 29 • 5:00 AM EDT • Politics • nbcnews.com
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The science of a splashdown: Why only 7 home runs have reached the Allegheny River on the fly

They gathered in their brightly colored kayaks and rubber rafts, several dozen of them at least. There along the north shore of the Allegheny River they...

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Jun 29 • 4:00 AM EDT • Science • post-gazette.com
Secret Alchemist, Sarelly and Borntostandout Are Among the Winners of The Business of Beauty Global Awards 2026

From emerging challengers to established disruptors, this year’s Global Awards winners are setting a new benchmark for beauty entrepreneurship.

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Jun 29 • 12:30 AM EDT • Business • businessoffashion.com
RedMagic officially confirms global launch of flagship OLED tablet

RedMagic has confirmed the Astra 2 as its next flagship gaming tablet. The device will arrive as the international version of the China-bound RedMagic Gaming Tablet 5 Pro, which is confirmed to feature a 185Hz OLED display and the Snapdragon 8 Elite Gen 5 chipset.

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Jun 28 • 9:03 PM EDT • Technology • notebookcheck.net
Andy Burnham’s meteoric rise tells us much about how politics and power are changing

The former may of Greater Manchester’s rise raises questions about the changing dynamics of political parties and leadership in an accelerated political climate.

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Jun 28 • 8:29 PM EDT • Politics • theconversation.com
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Cedar Crossing Casino to open in 6 months, BBQ restaurant prepares for business boom

CR Midnight Smoker BBQ sits next to the casino construction site. Owner Greg Stoll said business has not slowed during the build.

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Jun 28 • 7:25 PM EDT • Business • kcrg.com
CD Projekt is rebranding as CD Projekt Red, but confusingly, CD Projekt Red is still CD Projekt Red

CD Projekt has rebranded itself as CD Projekt Red – or CD Projekt Red Spółka Akcyjna, to be precise.

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Jun 28 • 3:55 PM EDT • Technology • eurogamer.net
Galaxy Z's days are apparently numbered: Accessories point to a very unusual name for Samsung's iPhone Ultra competitor

At first, it was called the Galaxy Z Wide Fold or the Galaxy Z Fold 8 Wide, then—according to generally reliable sources—simply the Galaxy Z Fold8. Now a fourth name has surfaced for the compact and wider iPhone Ultra alternative, that Samsung will unveil on July 22 alongside the updated Galaxy Z Fold 8 Ultra. However, as authentic as these images seem to be, there are doubts.

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Jun 28 • 1:33 PM EDT • Technology • notebookcheck.net
Trump’s Great American State Fair attendees say they haven’t noticed politics overshadowing the celebration

President Donald Trump kicked off the event with a headlining speech Wednesday after musical acts dropped out of the lineup citing concerns over partisanship.

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Jun 28 • 12:30 PM EDT • Politics • nbcnews.com
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Ben Stokes announces retirement

Ben Stokes, the England captain, has stunned the cricket world by announcing his retirement in the middle of one final epic spell of bowling.

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Jun 28 • 11:07 AM EDT • Sports • sports.yahoo.com
California Politics 360 full episode | What to expect on California's November ballot

KCRA 3 Political Director Ashley Zavala leads conversations on California's November ballot questions, including the proposed billionaire tax.

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Jun 28 • 10:55 AM EDT • Politics • kcra.com
Chicago Cubs news

Seiya Suzuki was the lone bright spot in the Cubs 6-2 loss Friday, hitting his 11th home run of the season

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Jun 28 • 8:00 AM EDT • Sports • sports.yahoo.com
Shingles is linked to inflammation in the brain. Research shows how to cut dementia risk.

Shingles, a condition triggered by the reactivation of the varicella-zoster virus in the body, can cause a “war zone” of inflammation in the brain.

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Jun 28 • 6:30 AM EDT • Health • nbcnews.com
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Lingering distrust, low vaccine rates threaten containment of Lancaster measles outbreak

LANCASTER, Pa. — A growing distrust of health professionals seems to be undermining their efforts in central and southeastern Pennsylvania to stop...

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Jun 28 • 4:00 AM EDT • Health • post-gazette.com
‘AIDS is not over:’ Behind a local group’s awareness campaign for HIV funding

Walk through East Liberty, Bloomfield or other Pittsburgh neighborhoods and you might see flyers with black-and-pink block print and an urgent message:...

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Jun 28 • 4:00 AM EDT • Health • post-gazette.com
Belkin launches new 14-in-1 Thunderbolt 5 dock with 140W charging and triple 4K display support

Belkin has launched a 14-in-1 Thunderbolt 5 Dock in China priced at 2,299 yuan (approximately $338). The Belkin dock ships with a 180W adapter and 1m cable and delivers 140W USB Power Delivery over a single Thunderbolt 5 connection, with bandwidth scaling from 80Gbps to 120Gbps for high-resolution display use. Belkin briefly listed the dock on its global website at $350 before removing the page, hinting at a global launch.

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Jun 28 • 3:25 AM EDT • Technology • notebookcheck.net
The Arts and Sciences of Judo: The New Edition Expands the Frontiers of Knowledge

The publication of Volume 6, Number 1 of "The Arts and Sciences of Judo" marks another important milestone in the development of judo research worldwide. As the International Judo Federation's interdisciplinary journal, under the supervision of Professor Sanda Čorak, it has become a recognised platform where science, education and the values of judo come together to deepen our understanding of the many dimensions of our sport. It also forms an integral part of the IJF Academy's mission to promote education, lifelong learning and the dissemination of knowledge throughout the global judo community.

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Jun 27 • 10:12 PM EDT • Science • ijf.org
Trump-backed Rep. Julia Letlow wins Louisiana Senate primary runoff

Letlow defeated state Treasurer John Fleming in the GOP runoff, NBC News projects. Incumbent Sen. Bill Cassidy did not make the runoff.

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Jun 27 • 9:44 PM EDT • Politics • nbcnews.com
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Uruguay federation reportedly cancels charter flight after World Cup elimination
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Jun 27 • 4:24 PM EDT • Sports • sports.yahoo.com
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Millions drop Obamacare health coverage after subsidies expire and costs rise

NEW YORK — About 3 million fewer people in the United States had Affordable Care Act health insurance plans in February compared with the same time...

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Jun 27 • 2:39 PM EDT • Health • post-gazette.com
Amazon Prime Day Is Over, but Our Editors Found 131+ Best Deals Still Live

We don’t know how long these discounts will last, so if something catches your eye, add to cart and checkout ASAP.

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Jun 27 • 11:05 AM EDT • Technology • nbcnews.com
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So many colorful Samsung Galaxy Watch 9 and Galaxy Watch Ultra 2 bands leaked ahead of launch

Anyone opting for the new Galaxy Watch9 or the redesigned Galaxy Watch Ultra 2 after July 22 will be spoiled for choice. Lots and lots of watch bands in different styles and colors will be available from Samsung at launch, as roughly 60 images leaked in advance shows.

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Jun 27 • 7:13 AM EDT • Technology • notebookcheck.net
Trump admin rule puts reproductive health care for 160K Pa. patients at risk, lawsuit says

Spotlight PA is an independent, nonpartisan, and nonprofit newsroom producing investigative and public-service journalism that holds power to account and...

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Jun 27 • 6:00 AM EDT • Health • post-gazette.com
Apple A20 Pro motherboard leak hints at notable memory and packaging upgrades

A leaked package layout of Apple's A20 Pro hints at several notable upgrades for the iPhone 18 Pro series. The next-gen SoC is said to feature a wider 96-bit memory interface, a redesigned packaging approach for improved thermals, and a larger Neural Processing Unit (NPU).

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Jun 27 • 4:33 AM EDT • Technology • notebookcheck.net
Hopewell's James Armstrong is the first sophomore to win Post-Gazette Athlete of the Year

James Armstrong is a teenager who doesn’t do well with downtime. Armstrong has a summer job as a maintenance worker at schools in the Ambridge Area...

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Jun 27 • 4:00 AM EDT • Sports • post-gazette.com
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Trossard, De Bruyne score and Belgium defeats New Zealand 5-1 to advance at the World Cup

A flurry of late goals helped secure Belgium’s place in the knockout rounds, while New Zealand are heading home without a win.

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Jun 27 • 2:31 AM EDT • Sports • nbcnews.com
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Egypt vs Iran Extended Highlights

Check out the full game highlights between Egypt vs Iran in the 2026 FIFA World Cup™. Announced by Tyler Terens and Maurice Edu.

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Jun 27 • 1:17 AM EDT • Sports • foxsports.com
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Our Editors Found 401+ Best Amazon Prime Day Deals Worth Shopping Before the Sale Ends

You have less than 24 hours left to shop deals across categories, and some of them are so good that they’re already selling out.

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Jun 27 • 12:00 AM EDT • Technology • nbcnews.com
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Trump refuses to sign housing bill, says GOP remains ‘well-unified’
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Jun 26 • 7:27 PM EDT • Politics • cnn.com
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Senators call for military healthcare program to cover autism therapy as a basic benefit

A letter to Defense Secretary Pete Hegseth follows an NBC News investigation into the military healthcare program’s restrictions on applied behavioral therapy.

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Jun 26 • 5:26 PM EDT • Health • nbcnews.com
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What if the economy gets better and it doesn’t help the GOP?: From the Politics Desk

Plus, Gavin Newsom’s next move in the billionaire tax fight.

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Jun 26 • 5:00 PM EDT • Politics • nbcnews.com
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Mel Brooks Is Turning 100! His 1 Tip for Longevity, a Healthy Life

The comedy legend and father of satire celebrates his big 100th birthday on June 28.

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Jun 26 • 4:09 PM EDT • Health • today.com
Mia Sara reflects on working with ‘weird guy’ Tom Cruise in 'Legend'

Mia Sara recalls working with Tom Cruise in the Ridley Scott film 'Legend,' saying the actor was 'very insecure.'

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Jun 26 • 2:50 PM EDT • Entertainment • ew.com
Factory Entertainment Announces Three More STAR TREK Collectibles, Including Gold-Pressed Latinum Bars

Factory Entertainment today unveiled three more STAR TREK replicas, including bars of gold-pressed latinum and Eline’s necklace from “The Inner Light”

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Jun 26 • 2:04 PM EDT • Entertainment • blog.trekcore.com
As Pa. measles outbreak worsens, state health official issue strong call to action: 'We are not just sitting back and watching this virus spread'

LANCASTER, Pa. — State Health Secretary Debra Bogen on Friday issued a strong call to action in the wake of a measles outbreak not seen in Pennsylvania...

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Jun 26 • 1:01 PM EDT • Health • post-gazette.com
Community Challenge Chaos Spreads

To celebrate the release of the Chaos Cubed game drop, the mayhem continues with our Chaos Spreads Community Challenge! Unite with your friends and play with the free add-on reward, courtesy of completing the Chaos Sparks Community Challenge. Players can collectively win a new Bedrock world for all from Blockception!

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Jun 26 • 1:00 PM EDT • Technology • minecraft.net
From The Sports Desk: The U.S. lost, but also saw return of star Christian Pulisic

The Americans may have lost their final group stage. But Pulisic, who had been nursing a calf injury, returned to action. He’s back just in time for the start of the knockout round.

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Jun 26 • 11:06 AM EDT • Sports • nbcnews.com
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Gambling disorder diagnoses spike after states legalized sports betting

Researchers analyzed millions of electronic health records and found a major difference between states that greenlit sports gambling and those that didn’t.

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Jun 26 • 7:02 AM EDT • Health • nbcnews.com
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Gambling disorder diagnoses spike after states legalized sports betting

Researchers analyzed millions of electronic health records and found a major difference between states that greenlit sports gambling and those that didn’t.

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Jun 26 • 7:02 AM EDT • Sports • nbcnews.com
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'A heavy impact:' Schwebel's closure leaves a sense of community loss

It’s the small things that residents across the region will remember when Schwebel’s closes its doors at summer’s end. Everything from...

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Jun 26 • 4:00 AM EDT • Business • post-gazette.com
It's Xbox's turn (again), as console prices keep going up

Microsoft announced a price hike for the Xbox Series consoles today, the third in little over a year. Effective August 1, the Xbox Series S, which launched in 2020 for $300, will cost $500 in the U.S. The Xbox Series X, which launched in 2020 at $500, will go for $800. This follows a round of PlayStation 5 price increases from Sony this spring, and a slow-motion increase for Nintendo’s Switch 2, which will kick in in the U.S. in September. (Mind you, there were also eight video game industry price hikes in six months of 2025). The chart up top shows the sudden ascent of console prices over the past year, a sudden surge in an already unusual hardware generation. Prices had been flat for years, now “up” is the new “flat.” Game console prices used to go down across the length of a console generation, but not this time around. Microsoft’s explanation for the new price hike today: We hoped another price increase would not be necessary, and we have spent the last several months working with suppliers on options. Unfortunately, console storage and memory prices have increased by more than 2.5x and we expect another doubling by the fall of 2027. The entire consumer electronics industry is struggling with the current components crisis, but the effects are particularly hard on consoles. Unlike phones, computers, speakers, and other consumer devices, consoles are typically not sold at a profit, but instead for less than they cost to make. This is an issue well beyond game consoles. Apple announced price hikes on its computers and tablets today as well. Game File is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe Item 2: Brutal Bungie cuts Bungie laid off “most” of its Destiny development team and some developers who worked on Marathon, the newest game from the struggling Sony-owned studio. A WARN notice issued by Sony to Washington State, where Bungie is based, tallied cuts impacting 292 workers, effective next month. That’s strictly for Bungie/Sony jobs in Washington and wouldn’t account for any elsewhere. The video I clipped below shows the redacted list of Bungie cuts filed to Washington State officials. As you’ll see, I had to scroll for a while… In a note emailed to PlayStation workers and published online, PlayStation game studios chief Hermen Hulst offered the following explanation for these latest cuts at Bungie: This is painful news, especially for talented colleagues whose roles have been eliminated. This decision was made only after extensive discussion and careful consideration, and I want to provide some context on how we arrived here. Over the past several months, together with Bungie leadership, we reviewed the studio’s long-term direction, development priorities, resource needs, and role within our broader portfolio strategy. We explored multiple alternatives before concluding that a reduction was necessary to align the studio’s resources with its current priorities and long-term goals. In 2022, Sony bought Bungie for $3.7 billion. The studio’s marquee game, the multiplayer live service shooter Destiny 2 was losing popularity at the time. Its next game Marathon, released earlier this year, has been well-reviewed but had a slow start. Bungie is renowned for making great shooter games, and Destiny fans have mourned the wind-down of Destiny 2. They’ve also expressed bewilderment over reports that Destiny 3 is not, per Bloomberg, immediately in the cards.

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Jun 25 • 8:21 PM EDT • Technology • gamefile.news
Politics Chat, June 25, 2026

A newsletter about the history behind today's politics.

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Jun 25 • 8:09 PM EDT • Politics • heathercoxrichardson.substack.com
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Serious statin side effects on muscles are extremely rare, new research confirms

Scientists created a new tool to help doctors predict a patient’s risk of severe muscle problems from taking a statin.

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Jun 25 • 6:30 PM EDT • Health • nbcnews.com
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Travelers Championship brings business boost and traffic headaches for Cromwell-area shops

As golfers compete at the Travelers Championship, nearby restaurants and shops in the Cromwell area are seeing the tournament’s impact on business, with some owners welcoming the crowds and others pointing to traffic challenges.

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Jun 25 • 6:16 PM EDT • Business • wfsb.com
This autism therapy is covered by many insurers. Why does the military’s plan restrict it?

Logan Cabiao started applied behavior analysis therapy for autism when he was 2. Several years later, TRICARE, the military’s healthcare program, imposed major coverage restrictions.

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Jun 25 • 6:06 PM EDT • Health • nbcnews.com
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Tennessee court temporarily blocks state health officials from sharing undocumented ill children’s information

The “state cannot go forward with the policy” until the judge makes a final decision, said the head of the Tennessee Justice Center.

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Jun 25 • 5:37 PM EDT • Health • nbcnews.com
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Less Islamism, More Nationalism

In Iran and across the Middle East, the bond between religion and politics is getting weaker.

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Jun 25 • 5:05 PM EDT • Politics • nytimes.com
Democratic socialists’ battleground test: From the Politics Desk

Plus, Pete Buttigieg is back on the campaign trail. And digging into Michael Whatley’s bio in the North Carolina Senate race.

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Jun 25 • 5:00 PM EDT • Politics • nbcnews.com
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Making Our Own Luck

We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.

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Jun 25 • 4:48 PM EDT • Science • goodscience.substack.com
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Catch Up with Highlights

Ecuador vs Germany

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Jun 25 • 4:40 PM EDT • Sports • foxsports.com
2-RBI days from Henry Davis, Brandon Lowe lead the Pirates to a series win against the Mariners

The Pirates continually walked a tightrope. The Seattle Mariners never let them fall. The Pirates beat the Mariners 5-1 on Thursday afternoon at PNC Park...

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Jun 25 • 3:20 PM EDT • Sports • post-gazette.com
Crews on scene of business fire in southwest Cedar Rapids

The fire happened at Tegeler Wrecker & Crane in southwest Cedar Rapids.

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Jun 25 • 1:25 PM EDT • Business • kcrg.com
Major blow for MacBook Ultra: Apple said to cancel M6 Pro and M6 Max

The Apple MacBook Ultra will either be released with the older Apple M5 Max, or its launch will be significantly delayed. This is because Apple is said to have halted development of the Apple M6 Pro and M6 Max in order to focus on the M7 series instead, which is expected to offer significantly stronger AI performance.

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Jun 25 • 1:20 PM EDT • Technology • notebookcheck.net
Is it Healthy to Eat Eggs Every Day? Dietitians Weigh In

Eggs are packed with protein, vitamins and omega-3s. But can you eat them every day?

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Jun 25 • 12:54 PM EDT • Health • today.com
From The Sports Desk: Is the Tartan party over?

Scotland’s hopes of advancing to the knockouts hang by a kilting thread.

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Jun 25 • 11:01 AM EDT • Sports • nbcnews.com
High-Signal Publisher
York, Community Unite for Hands-On Environmental Science Journey

A group of students, faculty, and Southeast Queens residents recently traveled from the York College campus to the waterfront campus of Kingsborough Community College (KCC) in the Manhattan Beach neighborhood of Brooklyn to set sail in the Research Vessel CUNY1 on Jamaica Bay, and to explore a part of the Hudson Raritan Estuary system.

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Jun 25 • 10:25 AM EDT • Science • york.cuny.edu