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49ers News: And then there were 53
Your daily San Francisco 49ers news for Sunday, August 30th, 2026
A fifth-grader in Kansas City clicked ball-and-stick atoms together in science class and asked her teacher if she'd made a real molecule — he photographed it, sent it to a chemistry professor, and at ten years old she became co-author of a published paper on a structure nobody had ever described
A ten-year-old's casual question about her chemistry model kit led to a published paper describing a molecular structure that had eluded professional scientists for decades.
“Zombie” Cells Reveal a Surprising New Driver of Chronic Inflammation
Dysfunctional mitochondria may drive age-related inflammation by helping switch on inflammatory genes, and blocking SLC25A1 reduced that activity. As people age, senescent cells accumulate in the body. These so-called “zombie” cells have stopped dividing but remain metabolically active, releasing inflammatory molecules that can contribute to persistent inflammation associated with frailty, cardiovascular disease, cancer, neurodegeneration, and
Seven new frog species were hiding beneath Madagascar’s forest floor
Scientists have discovered seven new species of Madagascar’s elusive diamond frogs, using DNA from modern and century-old museum specimens to solve a long-running biological puzzle. The findings reveal surprising hidden diversity and could help protect these little-known amphibians as their forest habitats disappear.
The next Cascadia megaquake could hit Oregon harder than expected
The Juan de Fuca plate beneath northern Oregon appears to be shallower than previously estimated, potentially making shaking from a future Cascadia megathrust earthquake significantly stronger. Scientists also found a deep basin beneath Tillamook that could trap seismic waves and intensify the shaking even further.
A new recipe unlocks “impossible” nanocrystals for LEDs, implants, and superconductors
Scientists have cracked a long-standing chemistry problem, creating nanocrystals from tough metal nitrides that were previously extremely difficult to produce at this scale. The breakthrough could turn familiar materials used in LEDs, implants, and superconductors into building blocks for flexible electronics, printable devices, and other technologies.
Putin Sparks Health Concerns With Deranged Tale of Polar Bear Slaughter
The Russian leader’s disconnect from reality was on stark display.
Body found behind Brookhaven business
A body was found behind Harbor Freight in Brookhaven Saturday afternoon. The Brookhaven Police Department and Lincoln County Coroner’s Office were actively working the scene at approximately 2 p.m. The […]
Fernbank Museum to explore the ‘Secret World of Elephants’ this fall
Visitors to Fernbank Museum of Natural History will have the opportunity to explore the intelligence, biology, cultural significance and conservation of elephants when a new exhibition opens this fall.
Johnson County business news: Aug. 29
Our Hospice earns five star patient care quality rating
Keto diet cut liver fat by 67% in a clinical trial
A ketogenic diet outperformed Mediterranean and low-fat diets in several measures of metabolic health during a clinical trial involving people with obesity, prediabetes, and fatty liver disease. All three groups lost about 10% of their body weight, but keto reduced liver fat by 67%, compared with 45% for the other diets. About half of the keto group also no longer qualified as having prediabetes after four to five months.
Scientists turn one of the hardest plastics to recycle into high-performance engine lubricant
Researchers have discovered a way to turn notoriously difficult-to-recycle PVC plastic into a key ingredient used in high-performance lubricants such as engine oil. The technique could give mountains of plastic waste a valuable second life while making lubricant production more sustainable.
Dogs may hold surprising clues to human longevity
Dogs and humans may have more in common when it comes to aging than scientists realized. Researchers with the Dog Aging Project found that patterns of small molecules in dogs’ blood were linked to longer or shorter lifespans in remarkably similar ways to those seen in people. These metabolic “fingerprints” could offer clues about the biological processes that drive aging, including metabolism, inflammation, and cellular stress.
Dry no more: Wave of new businesses, community events reinvigorate Bellevue
Lisa Saylor fondly remembers growing up in Bellevue. Born in the borough in 1968, Saylor recalls walking to and from school daily, along with the bustling commercial district that was Lincoln Avenue, Bellevue’s main thoroughfare. “Multiple drug stores, multiple eateries, shoe stores, Isaly’s was here,” she recalled. “It was very
Williamson College of Business Administration to Honor 4 Alumni
YSU's Williamson College of Business Administration will celebrate its 30th annual Outstanding Alumni Awards on Oct. 16.
49ers News: Roster cuts begin
Your daily San Francisco 49ers news for Saturday, August 29th, 2026
Judge rules Trump unlawfully targeted foreign students who criticized Israel
The ruling was a win for Stanford’s student newspaper, The Stanford Daily, and it followed another court victory for students targeted by the Trump administration last year.
Lil Nas X announces his mom has died in heartbreaking tribute
Lil Nas X has revealed that his mother has died.
The universe is still speeding up, but nobody knows why
A major new analysis challenges recent claims that the universe's expansion is slowing, finding that the evidence for cosmic acceleration remains strong. The findings preserve the leading role of dark energy, while leaving scientists with the enduring mystery of what this strange cosmic force actually is.
Australia’s red soil may be hiding a massive clean energy source
Researchers have discovered that Western Australia’s iron-rich rocks can naturally generate hydrogen and that the process may be boosted to produce much larger amounts. If it can be scaled up, the vast formations beneath the Pilbara could become a major new source of low-emission energy for Australia and potentially the world.
Will Meta settlement reduce physical, mental health risks for young users?
Experts say many of its terms may help limit use, negative social comparisons, but regulation may still be necessary
Inside Alabama Politics
Welcome to a new edition of Inside Alabama Politics! And a special welcome to new subscribers who have found your way here. For those who are new here, longtime Alabama politico David Azbell authored a great post on his Art of Alabama Politics about the history of IAP going back to its founder, Bessie Ford. […]
All hail Week 0, plus an apology for the poll
The Pulse Newsletter 📣 | This is The Athletic’s daily sports newsletter. Sign up here to receive The Pulse directly in your inbox. Good morning! Make amends with Cleveland today. Coming up: 👋 Hey, actual college football 👨⚖️ The judges are back 🏈 A new NFL mock draft Tomorrow at noon ET, across the planet, an American tradition officially begins. The college football season will be underway, with North Carolina coach Bill Belichick — still a strange concept to me — welcoming us with what will surely be a big smile. Welcome to Week 0, the part of the...
Music Legend, 82, Makes Bombshell Career Announcement Amid Health Fears
Fans had been concerned about the seven-time Grammy winner.
Texas Tech University Health Sciences Center Awarded Grant to Improve Diabetes Testing Access in Rural West Texas
The American Medical Association (AMA) awarded $50,000 to Adrian Billings, M.D., Ph.D., as part of a new grant to improve access to A1C testing in West Texas.
49ers' most agonizing roster decision looming on 2026 cutdown day
The San Francisco 49ers are approaching the final stages of the 2026 preseason with a roster that looks increasingly defined at the top but painfully unsettled underneath. With assistant head coach Chris Foerster helping steer daily operations during Kyle Shanahan’s recovery from an offseason vehicle accident, the exhibition slate provided really […] The post 49ers' most agonizing roster decision looming on 2026 cutdown day appeared first on ClutchPoints.
ILA's Blog
Literacy Daily is a space to connect educators, students, and leaders with the latest news, ideas, tools, strategies, and research in literacy instruction.
Scientists tested 212 plant-based meat alternatives. Every one contained fungal toxins
Every one of 212 plant-based meat alternatives and drinks tested in the UK contained at least one naturally occurring fungal toxin, though concentrations remained below recommended EU guideline levels. Researchers say the bigger question is whether regularly eating large amounts of these foods could lead to potentially concerning cumulative exposure over time.
Here Comes the Not-So-Very-Small Business Administration
I don’t make jokes—I just watch the government and report the facts. - Will Rogers The Small Business Administration (SBA) would like to change the definition of a small business. The summary of its proposal in the Federal Register is matter-of-fact in tone: The U.S. Small Business Administration (SBA or the Agency) is proposing new size standards for […]
Why scientists asked 1,000 people to bury their underwear
More than 1,000 volunteers buried cotton underwear across Switzerland to help scientists measure how active different soils are. The faster the fabric disappeared, the more biological activity was taking place underground. Gardens showed the fastest decomposition, while lawns had the least, revealing how strongly land management can shape soil life.
Scientists tracked 4,500 animals and found a surprising human effect
Scientists tracking thousands of animals found that our physical presence can reshape where wildlife moves and lives, sometimes as strongly as roads, cities, and other human development. Because different species reacted in very different ways, conservation efforts may need to become much more targeted.
Who's wild for Wile E.? 'Coyote vs. Acme' is finally here
Love movies? Live for TV? USA TODAY's Watch Party newsletter has all the best recommendations, delivered right to your inbox. Sign up now and be one of the cool kids.
Mitch McConnell’s Team Fuels Health Mystery With Cryptic Update
An update from Mitch McConnell’s staff has raised fresh questions about how he is faring in his reported recovery.
Weekend Entertainment | A Place to Roost at the Canfield Fair
The Canfield Fair will open Wednesday, and for the first time, visitors will have a place to roost with a beer, a cider or a glass of wine.
Patriots News: Pats-Browns ‘Bubble Bowl’ final audition before cuts
Daily news and links for Thursday, 8/27/26
Your dislike of eating bugs may be 9,000 years old
Ancient teeth and human DNA are revealing a surprising history of insect eating. Modern humans in northern Eurasia appear to have eaten insects only occasionally, while Neanderthals may have consumed them much more regularly. Populations near the tropics also retained genes that make insect exoskeletons easier to digest.
AI searched 100 million possibilities and found a cheaper way to 3D-print a NASA rocket alloy
Researchers used AI to search through more than 100 million possible settings for 3D-printing a high-performance NASA alloy. After only 40 experiments, the system identified six successful configurations, including one that worked at a record-low 500 watts. That could allow GRCop-42, currently difficult and expensive to print, to be made with much more widely available equipment.
“I jumped from my chair” – Astronomers spot Betelgeuse’s hidden companion
Astronomers have captured their clearest image yet of Betelgeuse’s long-suspected companion, potentially ending a search that lasted about 100 years. The surprisingly massive hidden star could help explain Betelgeuse’s changing brightness and may influence its future supernova.
Forbes Daily: Nvidia Beats Expectations As Data Center Business Grows
Today’s Forbes Daily covers an AI personal assistant, Meta's $18 billion settlement, FDA approves pancreatic cancer drug, Abercrombie and Fitch's market surge and more.
‘It feels amazing.’ Port Matilda area now has its own coffee shop after community support
“This shop wouldn’t be here without the support that everyone in and around Port Matilda has given us,” owner Salina Swancer said.
Oura Health's Tom Hale discusses his daily work routine
The CEO of Oura Health, Tom Hale, shares his wellness-focused routine, integrating health data and time management for productivity and balance.
Five fan-favorite Huskers that students should know this year
Saturdays in Memorial stadium and the Bob Devaney Sports Center will have many Husker athletes that incoming freshman should watch for.
Sports/Rec calendar: Aug. 28–Sept. 6, 2026
Upcoming recreation opportunities and college and prep sports
Smart nanoparticles light up brain cancer and destroy what surgery misses
Scientists created smart nanoparticles that can both illuminate hidden glioblastoma cells during surgery and destroy microscopic cancer left behind afterward. In mice, the treatment prevented recurrence and led to 100% survival at 60 days, though it has not yet been tested in humans.
Vitamin C won’t prevent most colds, but it may do one small thing
The belief that huge doses of vitamin C can ward off colds was popularized more than 50 years ago by Nobel Prize winner Linus Pauling. Since then, larger studies have found that vitamin C does not prevent most people from catching a cold, although regularly taking it may make severe symptoms slightly shorter or milder.
Eating more ultra-processed foods may raise prostate cancer risk by 30%
Ultra-processed foods make up a huge share of the American diet, and new research suggests they may carry another serious health risk for men. In a nationally representative study of more than 17,000 U.S. men, those who ate more ultra-processed foods, including soft drinks, packaged snacks, cereals, and processed meats, had roughly 24% to 31% higher risks of prostate cancer after accounting for factors such as age, smoking, race and ethnicity, and poverty status.
Scientists switch on a strange new form of magnetism in an ultrathin material
Scientists have found a surprising way to potentially switch on an unusual form of magnetism in ruthenium dioxide, a material that normally appears nonmagnetic. When the material was made into an ultrathin film only a few atomic layers thick and placed under strain, its electrons developed patterns consistent with altermagnetism, a recently proposed magnetic state with promising uses in advanced electronics.
Oneida Nation preparing to swear in new business committee
The committee is the overseer of daily operations and governance, and they’re elected every three years.
N.J. leaders closely watching N.Y. Climate law court battles
Leaders on both sides of the legal fight concerning New York’s Climate Change Superfund Act are speaking out.
Steelers Afternoon Drive: JPJ Negotiations Showing Steelers Stuck in Past?
Welcome to the Steelers Afternoon Drive, our new daily podcast featuring all the latest Steelers news and analysis. Alan Saunders […] The post Steelers Afternoon Drive: JPJ Negotiations Showing Steelers Stuck in Past? appeared first on Steelers Now.
FDA approves once-daily pill for deadly cancer after patients' survival rates nearly double
Revolution Medicines' Rasonque targets the RAS protein driving 95% of pancreatic adenocarcinoma cases, offering a critical option after chemotherapy fails.
I launched a Buy Canadian marketplace amid US tariffs; traffic surged
Toronto entrepreneur Valerie Crisp built a Buy Canadian marketplace amid US trade tensions. When things heated up, daily traffic nearly tripled.
Thousands of Alaskans to see health insurance costs rise sharply, after years of increases
Premera Blue Cross Blue Shield of Alaska's rates on the marketplace have already nearly doubled over the past five years, according to recent reporting by the Anchorage Daily News.
Dolly Parton showed us a different kind of Southern politics
Contributing columnist Paul Hyde reflects on Dolly Parton and why she was beloved across generations, faiths, and cultural boundaries.
Scientists may have found a shortcut to calorie restriction’s anti-aging benefits
Moderate calorie restriction lowered an immune protein called C3 that appears to help drive chronic inflammation as the body ages. Blocking the same protein reduced age related inflammation in mice, raising the possibility that future treatments could mimic some benefits of calorie restriction without severe dieting.
Manhattan-sized ice island breaks off Greenland’s Petermann Glacier
A Manhattan-sized ice island has broken away from Greenland’s Petermann Glacier after years of growing fractures weakened its floating ice tongue. Scientists expect two more huge sections could soon detach, potentially removing about 22 percent of the remaining ice tongue.
190-year-old DNA reveals a hidden pangolin species
DNA from a nearly 190-year-old museum specimen has helped scientists confirm a distinct Himalayan pangolin species hiding in plain sight in Nepal and northern India. The discovery could give conservationists a powerful new way to trace illegally traded pangolin scales back to the species and regions being targeted by poachers.
Potential Effects of Washington Politics in Illinois Elections
Candidates this fall for statewide office in Illinois are running with national politics in the periphery. Despite not winning the state, President Donald Trump gained ground in Illinois in 2024 compared to 2020. The effect of the first half of his second term on that […]
How OU's Elijah Thomas has 'elevated' to the next level
Sophomore Elijah Thomas looks to be a breakout candidate in 2026 after a season as a reserve wide receiver.
Metro 2039 Doesn’t Mess Around, and it Might Already Be My Favorite FPS in Years
In an age where single-player first-person shooters are slowly going extinct because they only make money for their publisher once while multiplayer live-service shooters vie for our time and attention on a daily basis (and often contain lots of bullsh*t, like microtransactions and/or drawn-out gameplay loops), Metro 2039’s single-player-only craftsmanship and attention to detail after my first few hours with it have me already prepared to call it my favorite first-person shooter in a long time.
'Hang our own banner': Kicker Tate Sandell on championship dreams
#Sooners' senior kicker Tate Sandell shared his championship aspirations in his return to OU for the 2026 season.
Free Entertainment, Cold Drinks, and Friendly Competition: The Empire Room is The Place to be at The Great New York State Fair
Featuring Daily Entertainment and Pour-Your-Own-Beer Wall by Harvey’s Garden Country line dancing, a Buffalo Bills pep rally, and a Silent Disco walk into a bar…or the Empire Room at The Great…
NASA’s Roman Space Telescope is ready to hunt thousands of alien worlds
NASA’s Roman Space Telescope is now enclosed inside its Falcon Heavy fairing and nearly ready for launch. Its mission could uncover thousands of exoplanets while helping scientists investigate dark matter, dark energy, and the accelerating expansion of the universe.
Turmeric compound may protect blood vessels from diabetes damage
A compound found in turmeric may help protect blood vessels from some of the damage caused by Type 1 diabetes. In rats, curcumin reduced inflammation, improved cellular signaling, and restored vascular health to levels resembling those of nondiabetic animals. The results hint at a possible new way to reduce the long-term cardiovascular risks of diabetes, but human trials are still needed.
Roger Denny deems Protect College Sports Act 'best hope we've got'
OU athletic director Roger Denny and President Joseph Harroz Jr. see the Protect College Sports Act as the most reasonable fix to college sports’ issues.
What we know about Dolly Parton's health struggles in her final days
Music and pop culture legend Dolly Parton has died at the age of 80, her family announced. NBC News’ Chloe Melas reports on what we know about the star’s health struggles in her final days.
Historic Kenyan drought reshaped livelihoods, health and daily life
The historic drought in northern Kenya affected nearly every part of life for a pastoralist community, from health and food security to where people lived and how they made a living, including a shift toward fishing as an important source of food and income.
Supercharged “natural killer” cells could be a powerful new cancer weapon
Researchers have found a way to supercharge natural killer cells, powerful immune cells that can attack cancer, so they can penetrate solid tumors and keep fighting once inside. In mice, these specially prepared tissue-resident cells slowed the growth of several tumors, including melanoma and head and neck cancers, and worked even better when paired with the antibody drug cetuximab.
Forces deep inside Earth helped Antarctica freeze before the Arctic
Scientists may have solved the mystery of why Antarctica froze millions of years before the Arctic. Slow-moving waves deep inside Earth gradually lifted East Antarctica, building mountains and a high plateau where snow and ice could survive even in a much warmer world. Once glaciers took hold, their bright surfaces reflected sunlight and helped cool the region further.
Shingles vaccine linked to 24% lower dementia risk
Older adults who received the Shingrix shingles vaccine were 24% less likely to be diagnosed with dementia over four years in a study of more than 500,000 people. Researchers estimate the difference could amount to roughly one dementia case prevented for every 17 people vaccinated.
New golf-themed entertainment spot coming to Springboro
Two Springboro entrepreneurs are putting their business experience and 5 irons to use filling a gap they see in the city’s entertainment options.
A look inside Iran: Professor outlines sentiment, cost pressures & politics
Seyed Emamian from Tehran Polytechnic University and co-founder of Iran's Governance & Policy Think Tank discusses daily life in Tehran amid the war, and why he thinks Iranians now see no chance of a peaceful deal with President Trump.
Falk College adds applied nutrition track to Bachelor of Science major
SU's Falk College launched a new applied nutrition track to the bachelor of science and newly students to the major can enroll this fall.
Falk College adds nutrition track to Bachelor of Science major
SU's Falk College launched a new applied nutrition track to the bachelor of science and newly students to the major can enroll this fall.
Atomic catalyst unlocks the hidden value of plant waste
Scientists have created a highly efficient catalyst that breaks down stubborn lignin from plant waste into useful chemicals under relatively mild conditions. By revealing exactly how the catalyst works at the atomic level, the discovery could help turn forestry and agricultural waste into renewable building blocks for fuels, plastics, and other materials.
Scientists find hidden “highways” guiding animal evolution
A sweeping analysis of thousands of animal genomes suggests that chromosomes do not evolve randomly but instead follow a limited number of irreversible “evolutionary highways.” These one-way genetic changes preserve clues to more than 600 million years of animal history and could even help researchers explore where evolution may head next.
‘We can’t accept falling behind’: Roger Denny addresses OU’s ‘Palace Project,’ stadium seat reduction
After OU announced plans last November to reduce Gaylord Family Oklahoma Memorial Stadium’s capacity by roughly 7,000 seats, athletic director Roger Denny provided new details on Aug. 20 on the
Russellville native finds niche in typewriter repair business
For Sam Freeman, older things are better. As an example, Freeman has started Barren River Typewriter, a new business in Bowling Green housed on Lovers Lane that services and sells […]
Leslie Parrish, 'Star Trek' and 'Batman' actress, dies at 90
Leslie Parrish, an actress and activist who starred in the 1962 movie "The Manchurian Candidate" and appeared in episodes of 1960s "Batman" and an episode of "Star Trek," has died.
Stephen Colbert makes rare appearance after end of 'The Late Show'
Stephen Colbert is in his post-"Late Show" era.
Stony Brook Southampton Hosts Falls Prevention Program to Support Healthy Aging
Stony Brook University will offer its S.A.F.E. (Strength, Awareness, Function, Education) Falls Prevention Program, a free eight-week workshop designed to help older adults improve balance and strength, reduce their risk of falls and maintain independence in their daily activities. Held at Stony Brook Southampton, the program provides older adults on the East End with practical
HOMETOWN HEALTH: U.S. sees sharp rise in type 2 diabetes among children and teens
The study’s authors said the findings should be a wakeup call for parents to support healthy eating and daily physical activity for kids.
Bird flu is spreading. Your backyard feeder could make it worse
Backyard bird feeders could become unexpected hotspots for H5N1 as Australia’s bird flu outbreak spreads, bringing species together in ways that rarely occur naturally. Experts say stopping feeding is safest, while smaller amounts of food, no hand-feeding, and careful cleaning can reduce the danger.
Common medications may change your gut for years
Common medications may reshape the gut microbiome long after the last dose is taken. In a study of more than 2,500 people, researchers found lasting microbial changes linked not only to antibiotics, but also to antidepressants, beta-blockers, acid-reducing drugs, and benzodiazepines. Some effects were still detectable years later, suggesting past medication use may strongly influence the gut bacteria people carry today.
A tiny “rainbow on a chip” could help supercharge 6G networks
Researchers have created a tiny chip that produces a stable “rainbow” of light capable of generating multiple high-frequency signals at once, potentially boosting the speed and capacity of future 6G networks. Its extreme precision could also make it valuable for quantum timing, navigation, radar, and even space-based technologies.
Nebraska flag football to play in 2027
Nebraska’s new women’s flag football team will open play in the spring of 2027, a year ahead of schedule, the school announced early Monday morning.
The first NFL player to return to college, plus a controversial WNBA ejection
The Pulse Newsletter 📣 | This is The Athletic’s daily sports newsletter. Sign up here to receive The Pulse directly in your inbox. Good morning! Congrats, you’re the Browns’ starting quarterback. Coming up: 📝 NFL –> CFB pipeline? ⏏️ Freedom’s ejection 🔥 Pristine vibes in Philly Last week, we discussed the concept — and your malaise — of the select group of NFL rookies eligible to return to college football via a judge’s order. In the time since, the situation has developed. Last night, former Ole Miss and Browns tight end Dae’Quan Wright,...
Cleveland Browns news: The waiting is the hardest part …
The latest Cleveland Browns news and notes from around the NFL in the August 24 edition of the Daily Dawg Chow.
49ers News: Life’s better with George Kittle and Christian McCaffrey
Your daily San Francisco 49ers news for Monday, August 24th, 2026
Dear Abby: Dad asks a lot of low-income live-at-home son
Daily advice column.
Husker Athletics offers giveaways at sporting events
The experience of Husker sporting events are more than just the game. All Husker sports offer fan promotions and giveaways to increase attendance and make the environment more fun.
Too much or too little sleep may make your body age faster
Both too little and too much sleep may be linked to faster aging throughout the body. Researchers analyzing 23 biological aging clocks found the lowest aging levels among people sleeping about 6.4 to 7.8 hours per day. Short or long sleep was also associated with numerous conditions affecting the brain, heart, lungs, metabolism, and digestive system.
NASA is about to launch a powerful new eye on the universe
NASA’s Roman Space Telescope has been cleared for final launch preparations ahead of a targeted August 30 liftoff aboard SpaceX’s Falcon Heavy. The powerful new observatory will probe cosmic expansion, the history of the universe, and distant exoplanets.
Executive Summary: Russell prefers a collaborative, progressive approach
Editor’s note: The Fort Smith Metro Daily News Executive Summary series is focused on looking under the title, so to speak, of a business, government, and non-profit executive in the...
Executive Summary: Russell prefers a collaborative, progressive approach
Editor’s note: The Fort Smith Metro Daily News Executive Summary series is focused on looking under the title, so to speak, of a business, government, and non-profit executive in the...
Scientists discover a real-life “dragon” and name it after Syrax
Scientists discovered a small, yellowish mountain horned dragon in Thailand and named it Acanthosaura syrax after a dragon from House of the Dragon. Found only in a narrow band of high-elevation forest, the distinctive new species could become a flagship for protecting its rare mountain habitat.
A hidden “on switch” in human DNA has finally been decoded
Researchers have used AI to uncover the DNA signature of a key genetic “switch” involved in turning genes on. After analyzing about 500,000 DNA sequences, the model identified the initiator in roughly 60% of human genes. The breakthrough could help predict the effects of harmful mutations and eventually contribute to decoding the broader genetic instructions that control gene activity throughout the body.