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CVS Health Corporation (CVS) is Attracting Investor Attention: Here is What You Should Know

Recently, Zacks.com users have been paying close attention to CVS Health (CVS). This makes it worthwhile to examine what the stock has in store.

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Sep 9 • 9:00 AM EDT • Health • finance.yahoo.com
GameSquare to acquire sports, music, and entertainment IP assets from FanEngine

Content provided by Seeking Alpha is intended for information purposes only, and that Seeking Alpha does not offer any personalist investment advice and is not a licensed securities dealer, broker, US investment adviser or investment bank.

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Sep 9 • 8:40 AM EDT • Entertainment • tradingview.com
Donald Trump Jr.'s venture capital firm rejects House Democrat's accusations of "insider political influence"

Rep. Jamie Raskin launched an investigation last month into the president's son's investment firm and its "almost clairvoyant" business moves.

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Sep 9 • 6:05 AM EDT • Politics • cbsnews.com
High-Signal Publisher
BridgePort Financial Solutions Appoints Osaic M&A Leader to Senior VP of Business Development

BridgePort Financial Solutions ("BridgePort"), a registered investment adviser (RIA) dedicated to helping fee-only advisors achieve their growth and succession goals, announced the appointment of RIA industry veteran Tina Decker to the role of Senior Vice President of Business Development. In this role, she will lead M&A strategy and execution to accelerate the firm's growth.

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Sep 9 • 6:00 AM EDT • Business • finance.yahoo.com
India's Serious Fraud Office recommends 'detailed' probe into Xiaomi's business in country

India's Serious Fraud Office has recommended Xiaomi be investigated for alleged irregularities in its business model and compliance with foreign investment law, potentially intensifying scrutiny of the ​smartphone maker, a government document shows.

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Sep 9 • 5:59 AM EDT • Business • reuters.com
Maven Securities LTD Purchases New Position in Caesars Entertainment, Inc. $CZR

Maven Securities LTD acquired a new stake in Caesars Entertainment, Inc. (NASDAQ:CZR - Free Report) in the 2nd quarter, according to the company in its most recent 13F filing with the Securities and Exchange Commission (SEC). The institutional investor acquired 283,136 shares of the company's stoc

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Sep 9 • 5:53 AM EDT • Entertainment • marketbeat.com
Maven Securities LTD Makes New $2.28 Million Investment in Live Nation Entertainment, Inc. $LYV

Maven Securities LTD acquired a new stake in Live Nation Entertainment, Inc. (NYSE:LYV - Free Report) during the second quarter, according to its most recent disclosure with the SEC. The institutional investor acquired 12,470 shares of the company's stock, valued at approximately $2,283,000. Other

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Sep 9 • 5:52 AM EDT • Entertainment • marketbeat.com
NEA partner Aaron Jacobson weighs in on open versus closed

Big Tech may be grabbing attention for its powerful new models, but investors like NEA's Aaron Jacobson want companies to explore their options.

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Sep 9 • 5:51 AM EDT • Business • businessinsider.com
Report that Netanyahu was warned before October 7 triggers political earthquake in Israel

An investigation published by 'Haaretz' claims the Israeli prime minister was informed by UAE President Mohamed bin Zayed, 10 days before the attack, that Hamas was planning a major operation against Israel.

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Sep 9 • 5:48 AM EDT • Politics • lemonde.fr
Gilead opens new research centre bringing together oncology, inflammation and research data science teams

The centre in California supports the company’s $32bn US investment

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Sep 9 • 5:30 AM EDT • Science • pmlive.com
Company that pledged 200 jobs in Charlotte leaves town for SC, loses NC incentives

The company, known for brands like Dirt Devil, announced a $5 million investment in 2015.

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Sep 9 • 5:27 AM EDT • Business • charlotteobserver.com
Wellington Management Group LLP Acquires Shares of 406,352 PENN Entertainment, Inc. $PENN

Wellington Management Group LLP bought a new position in shares of PENN Entertainment, Inc. (NASDAQ:PENN - Free Report) in the 2nd quarter, according to its most recent 13F filing with the Securities & Exchange Commission. The institutional investor bought 406,352 shares of the company's stock

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Sep 9 • 4:41 AM EDT • Entertainment • marketbeat.com
Did New Film Unit Just Shift AMC Stock’s Investment Narrative?

AMC Entertainment Holdings recently launched Leawood Films, a film distribution unit based in Los Angeles and Leawood, Kansas, aiming to bring more small and mid-sized movies into theatres worldwide while relying on fully financed projects to limit production risk. The new distributor uses AMC’s excess screen capacity and past concert-film marketing experience to secure theatrical placement for filmmakers who might otherwise struggle to find backing, while leaving most downstream revenue and...

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Sep 9 • 4:31 AM EDT • Entertainment • simplywall.st
96,800 Shares in Caesars Entertainment, Inc. $CZR Acquired by Governors Lane LP

Governors Lane LP acquired a new position in Caesars Entertainment, Inc. (NASDAQ:CZR - Free Report) during the second quarter, according to the company in its most recent filing with the Securities & Exchange Commission. The institutional investor acquired 96,800 shares of the company's stock,

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Sep 9 • 4:17 AM EDT • Entertainment • marketbeat.com
Worried about rising beef prices? WA farmers say, share a cow

CARNATION, Washington — Far from the refrigerated meat sections of Seattle's grocery stores, two dozen beef cattle relaxed in the afternoon drizzle falling on Carnation Farms' grassy fields. Livestock manager

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Sep 9 • 4:15 AM EDT • Entertainment • thederrick.com
Report: Messi plans to buy Spanish second-tier side Eldense

Argentina football great Lionel Messi is set to become majority owner of Spanish second-division club CD Eldense, Spanish sports daily AS reported late on Tuesday. AS said that the 2022 World Cup winner had reached a basic agreement with Colombian investment group TH to take over 100% of the shares.

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Sep 9 • 3:33 AM EDT • Sports • sports.yahoo.com
Sphere Entertainment (SPHR) Expands 4D Wizard Of Oz As Valuation Hinges On Growth Story

New 4D effects spotlight Sphere Entertainment’s product ambitions Sphere Entertainment (SPHR) just rolled out an expanded 4D package for The Wizard of Oz at Sphere, adding animatronic Winged Monkeys, themed scents, Glinda Glitter, pyrotechnic fireworks, and scented apples from September 25, 2026. For investors watching Sphere Entertainment, the latest 4D upgrade lands after a choppy few months, with the share price down about 11% over 30 days but still showing strong momentum through a 51%...

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Sep 9 • 3:21 AM EDT • Entertainment • simplywall.st
Amazon Cargo Jet Pilots Appeared to Try Aborting Landing, N.T.S.B. Investigation Indicates

The sequence of events detailed by National Transportation Safety Board investigators showed that the pilots lost crucial seconds before the plane ran off the runway in Miami.

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Sep 9 • 12:44 AM EDT • Politics • nytimes.com
How the surging yen could hit your portfolio

The yen carry trade lets investors borrow cheaply in Japan and put the money into higher-yielding currencies and riskier assets around the world.

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Sep 9 • 12:25 AM EDT • Business • businessinsider.com
HHS announces $383 million investment in mental health, crisis services

The U.S. Department of Health and Human Services announced over $383 million in SAMHSA grants to expand the 988 Lifeline, crisis teams, and rural healthcare.

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Sep 8 • 11:30 PM EDT • Health • kotatv.com
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Man accused of assault, inducing panic at Dr. Amy Acton event pleads not guilty

The armed Ohio man investigators said set off a security scare involving Democratic gubernatorial candidate Dr. Amy Acton pleaded not guilty in court Tuesday.

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Sep 8 • 9:13 PM EDT • Politics • news5cleveland.com
LIV Golf files bankruptcy with post-Saudi Future uncertain

LIV Golf filed for bankruptcy protection Tuesday, a dramatic fall for the Saudi-backed league that had big ambitions to challenge the supremacy of the PGA Tour. Saudi Arabia’s Public Investment

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Sep 8 • 8:36 PM EDT • Entertainment • thederrick.com
Carmignac Gestion Buys Shares of 100,508 Caesars Entertainment, Inc. $CZR

Carmignac Gestion bought a new position in shares of Caesars Entertainment, Inc. (NASDAQ:CZR - Free Report) during the 2nd quarter, according to the company in its most recent 13F filing with the Securities & Exchange Commission. The institutional investor bought 100,508 shares of the company'

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Sep 8 • 7:28 PM EDT • Entertainment • marketbeat.com
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Small business owners feel good now, wary about what's ahead: NFIB optimism index

Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.

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Sep 8 • 6:58 PM EDT • Business • nebraska.tv
Small business owners feel good now, wary about what's ahead: NFIB optimism index

Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.

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Sep 8 • 6:58 PM EDT • Business • kmph.com
Small business owners feel good now, wary about what's ahead: NFIB optimism index

Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.

kpic.com logo
Sep 8 • 6:58 PM EDT • Business • kpic.com
Small business owners feel good now, wary about what's ahead: NFIB optimism index

Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.

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Sep 8 • 6:58 PM EDT • Business • cbsaustin.com
Small business owners feel good now, wary about what's ahead: NFIB optimism index

Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.

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Sep 8 • 6:58 PM EDT • Business • foxbaltimore.com
Small business owners feel good now, wary about what's ahead: NFIB optimism index

Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.

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Sep 8 • 6:58 PM EDT • Business • 13wham.com
House rebukes Navy for refusing to investigate pilot brain injury

Several career pilots have raised concerns that repeated exposures may cause brain injuries that slowly accrue and lead to debilitating mental health problems.

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Sep 8 • 6:56 PM EDT • Politics • seattletimes.com
Ohio cannabis store voluntarily closes as state investigates ‘serious health events’

Arizona-based Vext Science said late last week it had voluntarily shuttered a cannabis store in Jackson, Ohio amid a health investigation.

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Sep 8 • 6:21 PM EDT • Health • mjbizdaily.com
Cardinal Health (CAH) Declines More Than Market: Some Information for Investors

In the latest trading session, Cardinal Health (CAH) closed at $240.49, marking a -2.71% move from the previous day.

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Sep 8 • 6:00 PM EDT • Health • finance.yahoo.com
Blackstone explores sale of ZO Skin Health, sources say

Investment firm Blackstone is looking to sell ​medical-grade skincare company ZO Skin ‌Health, which could be valued at around $2 billion in any deal, according to ​people familiar with the matter.

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Sep 8 • 5:19 PM EDT • Health • reuters.com
UNC Charlotte's Truman Lab awarded new $2.1 million grant from the National Institutes of Health

UNC Charlotte’s Truman Lab has secured a new $2.1 million grant from the National Institutes of Health to advance fundamental research on how cells maintain protein health, a process central to diseases ranging from cancer to neurodegenerative disorders. The five-year Maximizing Investigators’ Research Award from the National Institute of General Medical Sciences will support the […]

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Sep 8 • 5:09 PM EDT • Science • inside.charlotte.edu
UNC Charlotte's Truman Lab awarded new $2.1 million grant from the National Institutes of Health

UNC Charlotte’s Truman Lab has secured a new $2.1 million grant from the National Institutes of Health to advance fundamental research on how cells maintain protein health, a process central to diseases ranging from cancer to neurodegenerative disorders. The five-year Maximizing Investigators’ Research Award from the National Institute of General Medical Sciences will support the […]

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Sep 8 • 5:09 PM EDT • Health • inside.charlotte.edu
William O'Dowd IV Discloses Investment at Dolphin Entertainment with 19.0% Stake

William O'Dowd IV, the CEO of Dolphin Entertainment, Inc., reported beneficial ownership of 19.0% of the company's common stock. He filed a Schedule 13D on Sep. 08, 2026, after an earlier note exchange and a pre-set buying plan in 2025. The position includes common shares and the right to convert c…

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Sep 8 • 4:56 PM EDT • Entertainment • tradingview.com
Joint Observations with Swift removed from IXPE GO Cycle 4

The IXPE Guest Observer (GO) Program solicits proposals for investigations in any area of astrophysics (not constrained to IXPE’s prime science areas).

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Sep 8 • 4:45 PM EDT • Science • science.nasa.gov
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Colisée’s new owners pledge to ‘bring life back’ to Lewiston’s top entertainment, sports venue

The New York-based owners say the sale signifies a serious future investment in professional hockey in the city, as well as youth hockey, community events and more.

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Sep 8 • 4:44 PM EDT • Entertainment • sunjournal.com
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S&P 500 falls as AI worries hit software makers

The S&P 500 declined as AI competition fears hit software stocks and Middle East tensions lifted oil prices, with investors eyeing upcoming inflation data.

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Sep 8 • 4:43 PM EDT • Business • virginiabusiness.com
North Carolina MCO Alliance Health Taps Cortica to Rein in Autism Spending, Improve Outcomes

Ready to dive into what's shaping autism therapy-payer relations? Be a part of the Autism Investor Summit East this November 9–10. Get your tickets here.

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Sep 8 • 4:03 PM EDT • Health • bhbusiness.com
Rogers mixed-income community opens after $13 million investment

Three-story, 60-unit Olive Street Apartments recently opened at 700 N. 24th St. in Rogers. Roughly $13 million was invested in the attainable housing project, supported by the Walton Family Foundation....

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Sep 8 • 3:32 PM EDT • Business • talkbusiness.net
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Exclusive: Two of gaming’s biggest names are making a big investment in gaming’s future

The first thing to know about the Nova Games Foundation is that it isn’t about The Game Awards. And it’s not about PlayStation. The ambitious new grant program is the brainchild of Geoff Keighley and Mark Cerny. Keighley is the host of The Game Awards, Summer Game Fest and Opening Night Live. Cerny is a game designer of some 45 years and the lead architect for the PlayStation 4 and 5. But this new thing, which they’re revealing through Game File, isn’t about their day jobs. It’s an unaffiliated, standalone philanthropic project. It’s a bet on the artistic future of video games and a way, they tell me, to give back. “I’m nearing the end of my career,” Cerny recently told me over email. “I’m not done yet, but paying it forward—in the best way possible—is very much on my mind these days,” The Nova Games Foundation is a university-affiliated fellowship program, intended to offer six-figure grants to 20 young game designers each year, potentially for decades to come. It will offer no-strings-attached funding along with mentorship from games industry leaders, a combination intended to aid the development of groundbreaking new games, Cerny and Keighley told me. Nova will begin accepting applications in December, from class of 2026 and 2027 students from 13 affiliated gaming programs at universities in eight countries. The schools working with Nova include the New York University and the University of Southern California in the U.S., along with Abertay University in Scotland, Cnam-Enjmin in France, TH Köln in Germany, and the Royal Melbourne Institute of Technology in Australia, Cerny and Keighley said. The plan: $100,000 per recipient, with about a quarter of Nova fellows eligible for up to $500,000 more for projects that are shaping up particularly well. Payments will be delivered based on development milestones, and recipients will own their games. Nova will help promote the work, and developers will be free to pursue the publishers and platforms of their choice. Nova can help introduce fellows to publishers, but won’t take a cut. “I’ve always wanted to give back, but given my role in the industry, I’ve never felt it appropriate to commercially invest in games,” Keighley told Game File. “I’ve never owned stock in a game company or taken a financial stake in a game. Nova is philanthropy: we aren’t taking equity or looking to recoup the grants. The return we’re hoping for is creative—helping new voices make games and find their footing. “Mark and I have each made multi-million-dollar donations to establish the foundation, and we intend to keep contributing. We hope others will join us.” Cerny and Keighley have already hired an executive director, John Maconga, and a head of grants, recent Game Developers Conference director Ashley Corrigan, to help launch the effort. They’re working to recruit game industry leaders to join the effort. Keighley says “dozens of leading game directors have already expressed interest in contributing their time.” To name one, they’ve already gotten Josef Fares, lead designer from It Takes Two and Spit Fiction studio Hazelight on board with a donation and pledge to help out. “I’m proud to support Nova because it gives the next generation of creators the freedom to explore their creativity and hopefully bring their unique visions to life,” Fares told Game File. A plan forged from a friendship Keighley and Cerny have known each other a long time. It’s been so long, Cerny isn’t even sure exactly when they met. “We travel in much the same circles and I’m sure first intersected in the 90s or early 2000s,“ Cerny said. Keighley thinks it might have been during his stint writing a column about the mid-’90s console 3DO for a gaming magazine while Cerny was working on games with Crystal Dynamics or on Way of the Warrior with Naughty Dog. They became genuine friends about a 10 years ago, Keighley said, as they bonded over a shared love of games and a hope to improve the industry. “About a decade ago, we started having dinner a few times a year in LA,” Keighley said. “Just to catch up on life and the industry. Those conversations continued over Zoom during COVID. Nova grew out of that friendship and a question we kept coming back to: ‘What could we do to help the next generation of game directors get started?’” Keighley credits Cerny with the idea to figure out a way to put their money and time back into the industry. At one of those dinners, Keighley proposed the idea of a fellowship program. He’d recalled applying for a Rhodes Scholarship when he was younger. “Spoiler: I didn’t get it,” he said. He’d admired the MacArthur Foundation’s so-called “genius grants.” He liked these kinds of programs that recognized people’s talents and gave them the financial boost and the freedom to realize their potential. With Cerny, he had pondered what a game industry version of that could be. Keighley liked the idea of centering the fellowship on students, drawing inspiration from the accomplishments of Jenova Chen, the USC game design graduate who went on to lead the creation of gently moving, ambitious games such as Flower and Journey. Keighley also thought it could be useful to help promising graduates bridge the transition from student to professional. “Joining an established studio isn’t always possible—especially in today’s market—and even then, it isn’t the right path for everyone,” Keighley said. A fellowship, he realized, could give “graduates the time, resources and guidance to pursue a game of their own and not worry about the commercial viability.” As the idea took shape, Cerny also saw an opportunity to enable more games of a certain type: “The target with the grants is games as an artistic medium,” Cerny told me. “We like to say games with ‘artistic, literary and societal value.’” He added: “I’m a pretty big gamer myself, though I tend to gravitate towards the smaller and more unique or artistic titles, games like Neva, Abzu, Gorogoa, Stray or Outer Wilds. I was just playing and Roger on a flight to Japan, and was getting misty eyed to a degree that I was concerned that a flight attendant would ask me if I was OK. “So one fun benefit here is the games that will come out of the Nova Games Foundation – I can’t wait to play them myself.” Cerny believes it will also be useful for Nova fellows to hone their craft and team leadership skills. “We are looking for the next generation of visionaries,” he said. “The trick is that they will also need to have the executive function necessary to drive a small project to completion.” Game File is a reader-supported publication. To receive new posts and support my reporting, please consider becoming a free or paid subscriber. Subscribe Going big with this Keighley and Cerny may have started Nova and may be the ones primarily backing it right now, but they’re dreaming of something that goes beyond them. “Mark and I may have helped get it started, but one of our measures of success is that Nova grows into something the entire games industry feels a sense of ownership in,” Keighley said. “Our ambition is to build a lasting endowment supported by people and companies across the industry, and an equally broad community of creators willing to give their time and experience to the next generation.” The industry has a lot of knowledge that it can pass to the next generation, Keighley said: “Nova can hopefully become a way to connect that generosity with talented young creators at the moment when it can make the biggest difference.” Cerny, who told me he believes Nova can mature “over the next 10 or 20 years,” sees an opportunity to give generations of game makers momentum. “The industry has changed immeasurably since I started in games in 1982,” he said. “These graduates have talent, training and tools that outclass what we had back in the day by an astonishing amount. But they face a tough road ahead getting traction in the industry, and many could benefit from our support. We want to be there to give it to them.” “There’s a personal side to this, too,” Keighley said. “I don’t have children, and I’ve spent a lot of time thinking about what I can do for future generations. Games have been my entire career. I’ve been incredibly fortunate, and helping someone else build a life in this industry feels like a meaningful way to give back.” Cerny’s oeuvre dates back to Marble Madness and Sonic the Hedgehog 2. He has stood on stage multiple times to reveal the future of PlayStation hardware. He’s been an executive producer for a string of modern PlayStation classics such as The Last Guardian and Marvel’s Spider-Man. Nevertheless, of Nova, he said, “It’s certainly not like anything I’ve done before.” Nova Foundation applications will be due in December and the first wave of fellows will be announced in March 2027. A full list of participating universities and steps students and recent graduates can take to apply to become a Nova Fellow is forthcoming.

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Sep 8 • 3:12 PM EDT • Technology • gamefile.news
Google Cloud Boss Makes Bold Claim About AI Chip Business

In a boost for Google stock, cloud computing chief Thomas Kurian says AI chip business is more than twice the size of its closest rival.

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Sep 8 • 3:07 PM EDT • Business • investors.com
Bruins Announce Roster, Details for Rookie Camp and Prospects Showcase

The Boston Bruins prospect pool is heading to Buffalo. On Tuesday afternoon, the Bruins announced the roster, schedule, and livestream […]

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Sep 8 • 2:42 PM EDT • Sports • sports.yahoo.com
Missy Woods sentenced Tuesday

The former high-profile CBI analyst got a decade in prison on four counts A Jefferson County district court judge on Tuesday sentenced a disgraced former Colorado Bureau of Investigation DNA analyst to a decade in prison. Jefferson County District Judge Andrew Poland sentenced Yvonne “Missy” Woods to 10 years on the most serious felony charge, […]

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Sep 8 • 2:32 PM EDT • Politics • coloradopolitics.com
Ariel Investments names new leadership for private equity unit

The firm named Rodney Cohen co-CEO of Ariel Alternatives alongside Mellody Hobson.

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Sep 8 • 1:32 PM EDT • Business • chicagobusiness.com
Harvard, MIT scholars head north as Carney offers millions

Canada is investing $362 million to lure 64 top global scholars, including dozens from Harvard, MIT and other elite U.S. universities, to advance research in health and artificial intelligence.

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Sep 8 • 1:10 PM EDT • Science • latimes.com
Mississippi teen overcomes health challenges to harvest 12-foot alligator

Teen credits hunting for keeping her active through rare illnesses

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Sep 8 • 1:04 PM EDT • Health • wtok.com
Dallas police investigate small business break-ins in Bishop Arts District

Dallas police are investigating break-ins at multiple small businesses in the Bishop Arts District after suspects smashed doors and stole cash and items.

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Sep 8 • 12:43 PM EDT • Business • fox4news.com
New Cancer Care Technology at Intermountain Health St. Mary’s Improves Precision and Comfort for Western Colorado Patients

Intermountain Health St. Mary’s Regional Hospital has invested more than $2 million for new equipment and technology to improve quality of care and comfort of their patients receiving cancer care in the Grand Junction area.St. Mary’s Cancer Centers of Colorado purchased a new a new computed tomography (CT) scanner that offers several enhance...

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Sep 8 • 12:11 PM EDT • Health • news.intermountainhealth.org
German Politics Are Rocked After Election. What the Markets Are Keeping an Eye On.

German markets will focus on whether the nationalist’s party win forces the chancellor to alter structural reforms that appeal to investors.

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Sep 8 • 12:07 PM EDT • Politics • barrons.com
Campbell’s investing to turn around Snacks business

National media campaigns to feature Goldfish and Pepperidge Farm.

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Sep 8 • 11:28 AM EDT • Business • bakingbusiness.com
Robinhood Lands Crypto.com Deal, Underwriting Job For Oura. Goldman Hikes Target.

Robinhood takes minority stake in Crypto.com with prediction market deal, to underwrite Oura IPO, reports say. Goldman lifts price target.

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Sep 8 • 11:27 AM EDT • Business • investors.com
If You Invested $1000 In Sphere Entertainment Stock 5 Years Ago, You Would Have This Much Today

Sphere Entertainment (NYSE:SPHR) has outperformed the market over the past 5 years by 18.95% on an annualized basis producing an average annual return of 30.39%. Currently, Sphere Entertainment has a market

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Sep 8 • 11:15 AM EDT • Entertainment • benzinga.com
Louisiana concrete companies join forces to capitalize on construction boom

Two Louisiana concrete suppliers are joining forces with two out-of-state companies to pursue large-scale construction projects as billions of dollars in new industrial and technology investment move … Already an INSIDER? Sign in. Already an INSIDER? Sign in

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Sep 8 • 10:52 AM EDT • Business • businessreport.com
UnitedHealth’s Democrat investment, and surprise billing bloat debate

UnitedHealth execs shower a top Democrats with cash, and the No Surprises Act debate heats up.

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Sep 8 • 10:51 AM EDT • Health • statnews.com
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD

With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.

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Sep 8 • 10:50 AM EDT • Science • fiercebiotech.com
Corning Stock Climbs On Multibillion-Dollar Verizon Network Deal

Corning stock rose after the provider of optical communications gear for telecom networks announced a multi-billion agreement with Verizon.

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Sep 8 • 10:41 AM EDT • Business • investors.com
The New York Times

Seven of Ukraine’s top 10 military contractors won new business despite open criminal investigations for fraud, failures to deliver on earlier deals or the arrest of chief executives for corruption,...

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Sep 8 • 10:10 AM EDT • Business • facebook.com
What Makes Guardant Health (GH) a Compelling Bet?

Artisan Partners, an investment management company, released its second-quarter 2026 investor letter for the “Artisan Mid Cap Fund”. The letter can be downloaded here. Global equities rebounded sharply in Q2 2026, recovering from March lows as resilient economic data, strong corporate earnings, and continued AI investment improved investor sentiment despite inflation concerns, delayed rate cuts, and […]

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Sep 8 • 9:22 AM EDT • Health • finance.yahoo.com
Explainer: Why Air India's funding call has come under political scrutiny in Singapore

Air India's request for about $1.5 billion in funds from its owners — Tata Sons and Singapore Airlines — has sparked a debate in Singapore over state investor Temasek's exposure to the Indian ​carrier.

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Sep 8 • 9:05 AM EDT • Politics • reuters.com
Academy Sports + Outdoors Announces Participation in Upcoming Investor Conference

Academy Sports + Outdoors (the "Company") (Nasdaq: ASO), a leading full-line sporting goods and outdoor recreation retailer, today announced its participation in the upcoming Goldman Sachs 33rd Annual Global Retailing Conference to be held Monday, September 14 to Tuesday, September 15, 2026. Chief Executive Officer, Steve Lawrence, and Chief Financial Officer, Carl Ford, will participate in a fireside chat that will be webcast live on September 15th, at 11:30 a.m. Eastern Time. The live webcast

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Sep 8 • 9:05 AM EDT • Sports • finance.yahoo.com
Hims & Hers Health, Inc. (HIMS) is Attracting Investor Attention: Here is What You Should Know

Recently, Zacks.com users have been paying close attention to Hims & Hers Health (HIMS). This makes it worthwhile to examine what the stock has in store.

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Sep 8 • 9:00 AM EDT • Health • finance.yahoo.com
Memorial Hermann Health System Deepens Partnership with Strategic Investment in PartsSource

Check out today's featured companies who have recently raised a round of funding, and be sure to check out the full list of past healthcare IT fundings.

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Sep 8 • 9:00 AM EDT • Health • healthcareittoday.com
The British author who harvested mutant, jumbo peanuts from her atomic garden

Muriel Howorth founded the Atomic Gardening Association in 1959, recruiting hundreds of members.

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Sep 8 • 8:53 AM EDT • Science • popsci.com
Assessing Kelp Bed Expansion Around Kodiak Island in Alaska - NCCOS - National Centers for Coastal Ocean Science

Scientists from NOAA’s National Centers for Coastal Ocean Science Kasitsna Bay Laboratory joined a week-long mission to investigate the recent expansion of giant kelp forests in waters surrounding Kodiak Island, Alaska. Bull kelp, the predominant canopy kelp in the region, has been largely replaced by giant kelp in the last couple of decades. While both ... Read more

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Sep 8 • 8:39 AM EDT • Science • coastalscience.noaa.gov
Optimi Health to Participate in the H.C. Wainwright 28th Annual Global Investment Conference

VANCOUVER, British Columbia, Sept. 08, 2026 (GLOBE NEWSWIRE) -- Optimi Health Corp. (Nasdaq: OPTH) (CSE: OPTI) (“Optimi” or the “Company”), a commercial-stage pharmaceutical manufacturer of regulated psychedelic drug products, today announced that it will participate in the H.C. Wainwright 28th Annual Global Investment Conference. The conference will be held September 14-16, 2026, at the Lotte New York Palace Hotel. A Company presentation will be available on demand here beginning Friday, Septem

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Sep 8 • 8:30 AM EDT • Health • finance.yahoo.com
Science ministry to inject $3.49 bl for AI model

South Korea's science ministry plans to invest 4.7 trillion won ($3.49 billion) for a project to develop a homegrown artificial intelligence (AI) model that wil

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Sep 8 • 8:29 AM EDT • Science • koreaherald.com
Tesla Sales In China Continue Negative Streak; Exports Reach Key Level

Tesla China is offering new cash incentives through Sept. 30.

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Sep 8 • 8:09 AM EDT • Business • investors.com
Science ministry to inject $3.5 bil. to develop frontier AI model

Science ministry plans to invest 4.7 trillion won ($3.49 billion) for a project to develop a homegrown artificial intelligence (AI) model that will...

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Sep 8 • 8:04 AM EDT • Science • koreatimes.co.kr
Science ministry to inject 4.7 tln won to develop frontier AI model

SEOUL, Sept. 8 (Yonhap) -- South Korea's science ministry plans to invest 4.7 trillio...

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Sep 8 • 7:45 AM EDT • Science • en.yna.co.kr
Arm Extends AI Reach From Data Centers To Edge Devices

Chip designer Arm previewed new innovations in its AI compute portfolio spanning data centers to edge devices. Arm stock rose Tuesday.

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Sep 8 • 7:24 AM EDT • Business • investors.com
Political strategists outline their plan for Senate control and the algorithm cutting vital Medicaid funding

Plus, the NTSB investigators receive flight recorder data from the aircraft that crashed in Miami.

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Sep 8 • 7:19 AM EDT • Politics • nbcnews.com
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Cricket Australia opens Big Bash to privatisation

Cricket Australia opens the Big Bash to private investment - with some owners of franchises in The Hundred showing interest.

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Sep 8 • 6:56 AM EDT • Sports • sports.yahoo.com
Qualitas Energy buys Cero Generation’s 5.8GW European renewables business

Renewables investment platform Qualitas Energy has bought Cero Generation’s 5.8GW European solar PV and energy storage project portfolio.

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Sep 8 • 6:53 AM EDT • Business • pv-tech.org
Colombia business association labels hydrogen a $20bn ‘investment opportunity’

The National Business Association of Colombia (ANDI) believes the country’s hydrogen sector is an “investment opportunity worth over $20bn,” saying a pipeline of announced projects could attract enormous capital.

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Sep 8 • 6:20 AM EDT • Business • gasworld.com
Datameds, AI., and Tollo Health Partner with the NFL Alumni Association for Health Lives Here National Campaign Rollout

Stock Titan provides an ultra-fast stock market news feed and multiple tools for traders and investors.

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Sep 8 • 6:00 AM EDT • Health • stocktitan.net
Why VCs are questioning AI companies' big revenue claims

Investor skepticism is growing around the revenue claims powering the AI boom.

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Sep 8 • 5:00 AM EDT • Business • businessinsider.com
Gayle Benson buys another well-known New Orleans skyscraper, adding to growing property holdings

“There is tremendous opportunity in New Orleans, and investment creates confidence, confidence creates opportunity, and opportunity creates jobs and economic growth," Benson said. "We want to be part of that process and continue doing our part."

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Sep 8 • 5:00 AM EDT • Business • nola.com
Nykredit A S Invests $1.96 Million in Tencent Music Entertainment Group Sponsored ADR $TME

Nykredit A S bought a new stake in Tencent Music Entertainment Group Sponsored ADR (NYSE:TME - Free Report) in the 2nd quarter, according to its most recent disclosure with the Securities and Exchange Commission (SEC). The institutional investor bought 235,170 shares of the company's stock, valued

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Sep 8 • 4:08 AM EDT • Entertainment • marketbeat.com
Teladoc Health (TDOC) Could Be 58% Undervalued As A New CFO Takes Over

Why Teladoc Health Brought In A New CFO Teladoc Health (TDOC) has appointed Michael Grasher as Chief Financial Officer, effective 31 August 2026, giving investors a fresh focal point for assessing the company’s financial leadership and capital allocation plans. The Teladoc Health share price has eased in the past day and is down about 11% over the past month, while the 1 year total shareholder return has fallen roughly 19% and the 5 year total shareholder return has declined about 95%, so...

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Sep 8 • 3:26 AM EDT • Health • simplywall.st
UT Health San Antonio invests $1 billion to meet the growing demand for healthcare in South Texas

The multiyear investment strengthens patient care, research and healthcare infrastructure.

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Sep 8 • 3:00 AM EDT • Health • news.utsa.edu
Bill Belichick says UNC program is compliant with investigation

UNC football head coach Bill Belichick says his program has been compliant with an investigation.

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Sep 7 • 8:20 PM EDT • Sports • sports.yahoo.com
Is investing in mental health an overlooked opportunity?

EXPERT INSIGHT: If you’re an impact investor, what’s your first reaction to mental health? Do you immediately think of founders’ wellbeing, of highly scalable, AI-enabled therapy apps, or do you believe it’s a personal topic that isn’t investable at all?

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Sep 7 • 8:00 PM EDT • Health • pioneerspost.com
Police investigating possible animal abuse at Long Island boarding business
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Sep 7 • 6:35 PM EDT • Business • cbsnews.com
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Bill Belichick Finally Opens Up About Ongoing UNC Investigation

North Carolina head coach Bill Belichick broke his silence about the program's ongoing investigation.

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Sep 7 • 6:29 PM EDT • Sports • sports.yahoo.com
Elizabeth Holmes documentary upends Telluride Film Festival

A month before Holmes, the founder of Theranos, reported to prison to begin her 11-year sentence for defrauding investors, she welcomed a camera crew.

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Sep 7 • 6:12 PM EDT • Entertainment • seattletimes.com
EU seeks to reassure a Trump-rattled Greenland with promise of a new partnership and investment

The European Union is promising Greenland a stronger partnership and hundreds of millions of euros in investment, wanting to reassure Greenland after U.S. President Donald Trump's threats to take control of the island.

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Sep 7 • 5:29 PM EDT • Politics • pbs.org
Small bowel microbiome offers clues to women's health

A new study by investigators at Cedars-Sinai Health Sciences University has identified differences in the makeup and organization of the small bowel microbiome between women and men. The findings, published ...

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Sep 7 • 3:20 PM EDT • Health • medicalxpress.com
Did WEBTOON Entertainment Inc. Insiders Breach their Fiduciary Duties to Shareholders?

/PRNewswire/ -- Halper Sadeh LLC, an investor rights law firm, is investigating whether certain officers and directors of WEBTOON Entertainment Inc. (NASDAQ:...

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Sep 7 • 3:19 PM EDT • Entertainment • prnewswire.com
Driver arrested following hit-and-run investigation outside Bryan sports bar

A verbal altercation turned physical before a pedestrian was run over twice in the parking lot.

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Sep 7 • 3:12 PM EDT • Sports • kbtx.com
Over 20 dogs neglected at a LI boarding business: police

MANORHAVEN, N.Y. (PIX11) — An alleged case of animal neglect is being investigated after police went to the business on Saturday night, according to officials. At 10:44 p.m. on Saturday, police fou…

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Sep 7 • 3:03 PM EDT • Business • pix11.com
Federal Rural Health Transformation Program invests $120 million in Indiana

The Trump Administration is investing $120 million to expand healthcare services across rural Indiana.

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Sep 7 • 1:29 PM EDT • Health • starcitytv.com
Harvest Festival 2026: Applin Picking

Pokémon GO’s Harvest Festival runs September 29 to October 5, 2026. Find out about Shiny Applin, Mossy Lures, event bonuses, research, and GO Pass rewards.

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Sep 7 • 12:55 PM EDT • Technology • pokemongohub.net
Belichick, UNC Avoid Investigation Questions With Program In Flux

The Tar Heels had a bye week after upsetting TCU in Week 0.

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Sep 7 • 12:36 PM EDT • Sports • sports.yahoo.com
WHO Health Emergencies EPI-WIN webinar: Strengthening pandemic preparedness: from investment to implementation and impact

Pandemic prevention, preparedness and response (PPR) requires sustained investment to build and maintain the capacities needed to detect, prevent and respond to health emergencies. This webinar will explore practical experiences from country and regional initiatives, highlighting lessons learned on translating investments into stronger preparedness systems and more resilient health security capacities.

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Sep 7 • 11:42 AM EDT • Health • who.int
Luminis Health Working to Restore Systems After Cyberattack

Luminis Health in Maryland is investigating a cyberattack that has taken certain systems offline. Data breaches have been announced by Texas Orthopedic Luminis Health in Maryland is investigating a cyberattack that has taken certain systems offline. Data breaches have been announced by Texas Orthopedic surgeon Jeffrey David Reuben, M.D, Well Child in Tennessee, and Horizon Eye Care Laser & Eye Surgery Center in New Jersey.

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Sep 7 • 11:23 AM EDT • Health • hipaajournal.com
Should Value Investors Buy Option Care Health (OPCH) Stock?

Here at Zacks, our focus is on the proven Zacks Rank system, which emphasizes earnings estimates and estimate revisions to find great stocks. Nevertheless, we are always paying attention to the latest value, growth, and momentum trends to underscore strong picks.

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Sep 7 • 9:40 AM EDT • Health • finance.yahoo.com
EU chief unveils $232 million Greenland package

The European Union seeks to boost its relations with the vast island

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Sep 7 • 9:32 AM EDT • Politics • spectrumlocalnews.com
Global Growth Fund is Re-Evaluating Flutter Entertainment’s (FLUT) Strategic Fit

Sands Capital, an investment management company, released its second-quarter 2026 investor letter for “Sands Capital Global Growth Fund”. The letter can be downloaded here. Global Growth seeks the best growth businesses worldwide, leveraging a research team that explores both developed and emerging markets for sustainable competitive advantages. In the quarter, global equities rebounded strongly, driven […]

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Sep 7 • 9:13 AM EDT • Entertainment • finance.yahoo.com