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For Trump and Xi, a warm farewell and unfinished business
The presidents praised their relationship over tea and viewed America’s founding documents, with few apparent breakthroughs on the issues dividing their countries.
Cash registers, safe taken during at least 4 business burglaries on Chicago's South Side
Multiple businesses were broken into on Friday morning, and burglars left cash registers and a safe.
At least 5 South Side businesses burglarized, including some in Bronzeville, Hyde Park
At least five businesses were burglarized early Friday morning on Chicago's South Side.
Why the 2026 election could be the worst midterm for the GOP this century
The Republican Party’s two worst midterm elections in the 21st Century were in 2006 and 2018. In the former, an unpopular Middle Eastern war cost George W. Bush dearly. In 2018, voters balked at the upending of historic norms and chaotic style of a new president named Donald Trump.
Scheduling your mammogram with CHI Health
With Breast Cancer Awareness Month approaching, CHI Health is focusing on prevention and encouraging women to schedule a mammogram.
The Greatest Article That Has Ever Been Written
The most entertaining story I’ve ever read. All hail Sara Bareilles. The best casting news. Are you a faithful or a traitor? We just live in Veep now. I have never been more entertained than when read...
Report: Cubs, Red Sox Could Finish Series In Tampa
As a looming nor’easter forces scheduling shifts and doubleheaders, the regular-season finale faces a potential relocation to Tropicana Field to bypass Boston’s worsening weekend weather forecast.
Ed Sheeran cancels New England concerts as Nor'easter looms
Ed Sheeran can’t be in love with the shape of this forecast
Ed Sheeran cancels New England concerts as nor’easter looms
Ed Sheeran can’t be in love with the shape of this forecast.
Ed Sheeran cancels New England concerts as Nor'easter looms
Ed Sheeran can’t be in love with the shape of this forecast. A weekend nor’easter bound for New England has prompted the cancellation of the English pop singer’s concerts Friday
Ed Sheeran cancels New England concerts as Nor'easter looms
Ed Sheeran can’t be in love with the shape of this forecast.
Guardant Health co-CEO Helmy Eltoukhy on breast cancer test
Guardant Health co-CEO Helmy Eltoukhy joins CNBC's 'Squawk on the Street' to discuss the breast cancer test, managing cancer with a blood test, and more.
Trump’s newest rebranding project: The technology formerly known as AI
He’s trying to label the technology as “superintelligence” and says he pitched the term to Xi Jinping.
Arkansas Invests 54 Million to Boost Rural Health and Workforce in 54 New Projects
Governor Sarah Huckabee Sanders announced $54.6 million in new rural health funding for 54 projects across Arkansas Thursday, including eight awards totaling more than $5 million for projects serving Southeast Arkansas. Jefferson Hospital Association received two awards totaling $1.03 million. Of that amount, $360,000 will […]
Everett firefighters prevent dumpster fire from spreading to businesses, apartments
Multiple 911 callers said people were trying to put out the flames with fire extinguishers.
Evaluating UW Offense, Matchups Against Minnesota
The UW offense found its stride last week against Eastern Washington. It had three explosive run plays, ten explosive passing plays, and over 500 yards of offense. The run game, and how the offensive line contributes to it, continues to be the weak point for this offense, however. Jedd Fisch’s group is averaging 129 rush …
Mets close out 2026 season against Nationals
The season ends with a whimper as the two bottom teams in the NL East face off looking to escape the cellar.
Three Prop Bets I Love: Nebraska at Michigan State
Capitalize on Cam Edwards’ workload and Jordan Savoury’s consistency as the Spartans return home, looking to dominate the ground game and exploit Nebraska's defense in East Lansing.
New movies to watch this weekend: See 'Primetime' and 'Heart of the Beast' in theaters, rent or buy 'Super Troopers 3,' stream 'Tuner' on Paramount+
In theaters now: Robert Pattinson wows in his turn as "To Catch a Predator" host Chris Hansen — and don't underestimate the power of Brad Pitt and a dog.
New Jersey Hall of Fame Class of 2026: SZA, her parents, charm crowd
R&B superstar SZA professed her love for New Jersey at the Thursday, Sept. 25 New Jersey Hall of Fame Ceremony at American Dream in East Rutherford.
Pioneer of China NewCo model sued in US over trade secret misuse, double-dealing
A legal feud unfolding in New York is putting a spotlight on the work of a business development veteran who is credited for pioneering one of biopharma’s hottest dealmaking mechanism: the China “NewCo” model. In a lawsuit originally filed in New York state court and recently moved to federal court, China’s Lepu Medical Technology has alleged that biopharma business development consultant Su Zhang, who was hired to help shop its GLP-1 weight-loss candidates to Western partners, engaged in corporate double-dealing and trade secret leaks. According to the complaint, while acting as Lepu’s primary dealmaking liaison for a group of obesity and metabolic disease drug candidates, Zhang was secretly double-dipping as the acting chief business officer for a direct competitor, BrightGene Pharmaceutical. “She never adequately disclosed the role, never sought Lepu’s consent, and never proposed any safeguard,” Lepu alleged in its complaint, which was filed in July after Zhang’s consulting firm, CoDevCo, sought certain transaction-based success fees from its angry customer through an arbitration process in Singapore. Lepu, the parent company of Lepu Biopharma, has asked Zhang to pay back its $500,000 retainer and disgorge all benefits she received during the alleged breaches of fiduciary duty, plus other damages and relief. The company has also requested the court grant injunctions to protect Lepu’s trade secrets. The ill-fated partnership officially kicked off in December 2024, when Lepu tapped CoDevCo as its “exclusive business development mechanism” to identify collaborators for the company’s drug candidates. According to Lepu’s complaint, Zhang personally negotiated and signed the agreement as managing director for CoDevCo, which used her home address. Before the Lepu deal, Zhang made a name following a short stint as the global head of business development for Hengrui Pharmaceuticals. It was during her tenure that Hengrui signed a landmark deal granting exclusive rights for a portfolio of GLP-1 assets to Hercules, which was at that time newly established by a group of private equity and venture capital firms. In addition to the regular upfront and milestone payments, Hengrui also gained an equity stake in Hercules, which later became Kailera Therapeutics. The Hengrui-Hercules deal opened a new paradigm, where a Chinese biopharma company spins off certain early-stage assets to investors for further development through the creation of a new company abroad. The “NewCo” model quickly came into vogue as it allows Western investors to access high-potential assets originating from China at an early stage while giving the Chinese licensors an opportunity to reap long-term benefits through equity stakes in the new firms. The NewCo model proved its value when Kailera staged a record-breaking $625 million IPO on Nasdaq this April, merely two years into the Hengrui deal. Related Kailera CEO 'knew we were in a good spot' before obesity biotech's record-breaking $625M IPO On her LinkedIn page, Zhang described her work at Hengrui as “[b]uilding team and capability from the ground up,” forming NewCo and major pharma partnerships worth billions of dollars. Lepu clearly wanted that kind of track record to help boost its own cardiometabolic portfolio, which includes a range of assets for obesity, Type 2 diabetes, fatty liver disease and muscle preservation during weight loss treatment. “Lepu’s pipeline is very valuable, but only if Lepu could secure the right international partner to expand into the overseas market during the available commercial window,” the company argued in its complaint. The Chinese biotech said it had little knowledge of U.S. laws, customs or business practices in the business development field, and therefore “needed to rely entirely” on the expertise of Zhang and her team as the firm’s first engagement of a U.S.-based BD consultant. “Zhang’s dominating influence on the business development strategy is further evidenced by the fact that she personally controlled the business-development communications on behalf of Lepu with potential partners,” Lepu said in its complaint. After entering the deal, Zhang introduced Lepu to her four associates. According to Lepu’s version of events, all of them were allegedly employed at different time points to perform similar jobs at other Chinese companies that Lepu described as its competitors, while having access to Lepu’s confidential information. As such, Lepu described Zhang’s team as “a roster of individuals whose primary professional loyalty, by virtue of their concurrent full-time employment, ran to Lepu’s competitors.” As well as the specific examples set out in the case, a look at Lepu’s deals over the period suggests Zhang may have been involved in at least one transaction. During their partnership, Lepu, through its subsidiary Shanghai Minwei Biotechnology, also out-licensed its GLP-1/GIP/FGF21 agonist MWN105 to a NewCo called Sidera Bio in the fall of 2025. The deal included an upfront and near-term payment of $35 million, up to $1.01 billion in milestones, and a 9.99% stake in the Danish startup. It seems likely that Zhang facilitated the Minwei deal given that Lepu is on record as having used CoDevCo as its “exclusive business development mechanism.” The big shock for Lepu came in the form of a news article on June 25, 2025. The article, reporting on phase 2 data for BrightGene’s GLP-1/GIP receptor agonist BGM0504, identified Zhang as acting chief business officer of the Lepu rival. Blindsided by her association with BrightGene, Lepu confronted Zhang in July 2025. “Lepu was given assurances that there was nothing to be concerned about and told that Zhang would explain the matter to Lepu,” Lepu alleged in its complaint. “Zhang never did.” Lepu claimed that Zhang had the motive and opportunity to steer potential prospective partners toward BrightGene or other competitors. Later, in February 2026, one of Zhang’s associates joined BrightGene as the vice president for global business development, according to the complaint. Around the same time, Lepu sent written demand letters asking Zhang to account for her BrightGene role, identify what confidential data were shared with the rival firm, and provide any conflict-of-interest or firewall policies during the engagement. According to Lepu, neither CoDevCo nor Zhang answered the questions in their responses. Related Novo vs. KBP: How a $1.3B deal turned into a fraud accusation and an international legal fight In a motion to dismiss filed with the U.S. District Court in the Eastern District of New York on Sept. 4, Zhang’s legal team argued that Lepu’s agreement was signed with CoDevCo, and that an employee of the contractor does not owe fiduciary duties to the client. In its complaint, Lepu said: “That CoDevCo was the contracting entity does not insulate Zhang from personal liability for duties she personally undertook and personally breached.” Taking the argument one step further, the defending party argued that the consulting agreement “does not create a fiduciary relationship even between CoDevCo and Lepu; instead, it identifies CoDevCo as an independent contractor retained to market Lepu’s business to potential western partners.” Although CoDevCo was Lepu’s exclusive business-development contractor, there were no terms stipulating that the consulting firm should serve only Lepu, Zhang’s lawyer noted. As to Lepu’s claims that Zhang misappropriated trade secrets, the defendant argued that Lepu authorized the use of the information so Zhang’s team could perform their service per the agreement. In a rebuttal filed on Sept. 11, Lepu’s lawyer set out why they believe the Chinese biotech satisfied New York law’s misappropriation definition by alleging that the defendant used a trade secret “in breach of a duty or through improper means.” As an alternative to dismissing the suit, the defendant suggested the action should be stayed pending outcomes from the arbitration of a separate case in Singapore. While NewCo pioneer Zhang is defending her business arrangements, momentum behind the NewCo trend has continued unabated into 2026. Through August, Chinese biotech assets have spurred 15 NewCo deals this year, according to local trade publication PharmaDJ.
Herd Health Playbook: Vaccines, Timing and the Value of a VCPR
A tailored vaccination schedule and an established relationship with a veterinarian help producers prevent outbreaks and handle emergencies before they start.
Mississippi Department of Health to host maternal and infant health conference
The conference will also break down the newly released dietary guidelines for Americans and what they mean for pregnancy, postpartum and breastfeeding.
Here are the midterm polls that caught our eye this week.
Another round of interesting midterm polls this week find an electorate dissatisfied with President Donald Trump and mostly souring on Republicans in marquee races.
Patrick Mahomes tops Forbes NFL's Highest-Paid Players 2026 list
Kansas City Chiefs quarterback Patrick Mahomes tops Forbes NFL's Highest-Paid Players 2026 list | @EdEastonJr
To improve chronic care, this Durham startup tracks life outside the doctor's office
Through anonymized mobile surveys, rXperius helps health orgs account for non-medical factors affecting patient well-being.
After two-year hiatus from concerts, Arrowhead back in business with big names
The World Cup caused Chiefs’ stadium to be unavailable for concerts, but there will be at least three in 2027.
Why I invite the far left and right to my college debates
My peers deserved to engage with their views. What else is college for?
Some dementia patients grow lucid near the end. Scientists hope it’s a clue.
Accounts raise tantalizing questions about what happens inside a brain afflicted by dementia and whether cognitive abilities could possibly be restored.
New study suggests the aging brain is adapting, not declining
As we get older, the brain prioritizes wisdom over remembering details for good reason, according to researchers.
Leadership Is Measured by the Doors You Open
Leadership isn't measured by the title you hold or the deals you close. It's measured by the doors you open for others - especially for the next generation.
Taylor Swift has a message for the haters on her new song ‘Cleveland!’
Swift, who dropped a deluxe version of her latest album on Friday, included an ode to her husband, Travis Kelce.
Visit Manchester, NH, names Jessica Martin as first executive director
Under Martin’s leadership, Visit Manchester will focus on building awareness of the city, encouraging people to discover what is already here, and creating opportunities for visitors to experience Manchester year-round
$300,000 Catholic Medical Center investment expands dental and health care access for Manchester’s most vulnerable residents
The investment is the second installment of CMC’s $2 million, three-year commitment to the programs, bringing its total support to date to $600,000
STAY INFORMED: School closed due to staff illness
A local school is closed Friday morning because of illness.
Intelligence from Chinese groups aiding in Iran’s increasingly effective targeting of US sites, sources say
Satellite imagery and intelligence support provided by Chinese groups has helped Iran threaten ships in the Strait of Hormuz and launch precision strikes on US military bases in the Middle East, part of a dramatic improvement in Iranian targeting capabilities over the past several months, according to a series of recent American intelligence assessments described to CNN by four sources.
Explosive Intensification for Hurricane Polo
Several ingredients came together off the Pacific coast of Mexico to generate one of the strongest storms the eastern Pacific basin has ever seen.
ROUNDUP: Science Hill, Sullivan East cap undefeated district runs
BLOUNTVILLE — Behind a balanced offensive effort, Science Hill's volleyball team completed a perfect run through District 1-AAA competition this regular season.
Local Omaha business says it's still in style to be a good neighbor
Get N Go Fish has served East Omaha for 30 years. Owner Jerel Ford shares how community keeps the family business going.
ROUNDUP: Science Hill, Sullivan East cap undefeated district runs
BLOUNTVILLE — Behind a balanced offensive effort, Science Hill's volleyball team completed a perfect run through District 1-AAA competition this regular season.
Trump administration appeals to Supreme Court as 3rd-country deportations are thrown into question
A ruling to halt deportations of people to countries other than their own threw a core immigration policy of the Trump administration into question, at least temporarily, and prompted a desperate appeal to the Supreme Court on Thursday.
Congo faces health worker shortage as Ebola remains out of control, WHO says
Congo is running short of health workers to staff treatment centers for history's fastest-growing Ebola outbreak, particularly in the eastern province of North Kivu where cases have surged 73% over three weeks, the World Health Organization said Wednesday.
Berlin Greenhouses to be Sold at Foreclosure Auction in October: Business NH Magazine
It is now clear what the next step for the greenhouses off East Milan Road will be: the auction block on Oct. 28 at 11 a.m.
At least 30 arrested, including actors, politicians during anti-Netanyahu protest outside UN
Police arrested at least 30 people, including actors and politicians, during a protest outside the United Nations headquarters on Thursday against Israeli Prime Minister Benjamin Netanyahu, hours before he addressed the UN General Assembly.
Oregon political leaders demand emergency federal assistance for East Evans Creek Fire
Initial request was denied in late July; fire was sparked by a rollover crash in which a teen driver has been arrested Multiple Oregon federal lawmakers are requesting that the […]
Police arrest actors, politicians protesting against Netanyahu outside UN
By Maria Tsvetkova NEW YORK, Sept 24 (Reuters) - Police arrested at least 30 people including actors and politicians as they protested outside United Nations headquarters on Thursday against Israeli
Police arrest actors, politicians protesting against Netanyahu outside UN
Police arrested at least 30 people including actors and politicians as they protested outside United Nations headquarters on Thursday against Israeli Prime Minister Benjamin Netanyahu ahead of his speech at the General Assembly.
'The Beast in Me' will return for season 2 at Netflix
Claire Danes as Aggie Wiggs and Matthew Rhys as Nile Jarvis in episode 3 of season 1 of 'The Beast in Me.' (Netflix)
Democratic House candidate arrested during Netanyahu protest in NYC
Darializa Avila Chevalier was among several progressive elected officials and nominees who protested Netanyahu's speech at the U.N.
Iranian president claims Mojtaba Khamenei is in good health, able to govern
Iranian President Masoud Pezeshkian discusses Supreme Leader Mojtaba Khamenei’s health and his conversations with him on ‘Special Report.’
HHS Seeks Public Input on Wireless Technology Safety, Scientists Urge Caution
A call for the public to share their experiences on the health impacts of wireless technologies has raised eyebrows among scientists.
Delta Peanut receives $5 million loan to continue operations
Peanut farmers in Northeast Arkansas and in the Missouri Bootheel have potentially staved off a disaster. A $5 million loan has been allocated from the Governor’s Quick Action Closing Fund...
Steph Curry visits East Oakland school, talks vision issue
Steph Curry is battling the progressive eye condition keratoconus, which effects vision.
Senate rejects measure to block Trump from ordering more strikes on Iran
The administration ignored passage of a similar resolution in June, arguing that it lacks the force of law.
How every senator voted on the Iran war powers resolution
The Senate failed to block President Donald Trump from ordering further strikes on Iran in a 49-50 vote.
Mercy Health to host breast cancer awareness Lunch & Learn Oct. 1
Mercy Health — Paducah will host a free community education event focused on breast cancer prevention, early detection and the latest advances in treatment in recognition of Breast Cancer Awareness
Griffin MSI’s new design must go back to the drawing board: ‘Carbuncle in the park’
The two-story, 458-foot long entry pavilion threatens to visually overpower the landmark museum's historic entrance and great lawn.
State police investigating after John Deere tractor stolen from Western Pennsylvania business
Police said an unknown-aged male wearing a mask, a hat, jeans and a hoodie stole the tractor that was parked outside.
Eagles Face Massive Defensive Question Before Bears Week 3 Showdown
The Philadelphia Eagles are looking for some payback as they take on the Chicago Bears in Week 3.Last season, the Bears torched the Eagles on the ground, rushing for 281 yards to win 24-15 on Black Friday. It was a rough loss for a Philly team that was trying to close out the NFC East […] The post Eagles Face Massive Defensive Question Before Bears Week 3 Showdown appeared first on HEAVY.
Mental health concerns grow after 8 suicide attempts during Lincoln deployment
The Navy confirmed eight suicide attempts across the USS Abraham Lincoln strike group during its extended Middle East mission.
Trump officials end review of how arch could harm historic sites
A required consultation process with local preservationists is being terminated, a Trump appointee said Thursday.
Taylor Swift Just Teased the 'Patient Zero' Music Video and I Think It Confirms *This* Theory
Taylor Swift announced that she'd be premiering a new music video, "Patient Zero," a the VMAs this weekend. Here's why I think it points to this long-standing theory.
Trump ad airing with government funding despite law against ‘propaganda’
A TV ad boosting President Trump and saying that it was paid for by the U.S. government is airing in two major markets despite a federal law against using tax funds for "propaganda."
Paid influencers quietly push political messaging on social media
Paid content creators are quietly pushing political messaging on social media platforms like TikTok to shape public opinion. Fox News political analyst Gianno Caldwell reacts to the trend and a new California law requiring political ad disclosure.
Philadelphia Union put scorching form to test vs. Orlando City
By Jaime UribarriTwo resurgent teams meet on Saturday when the Philadelphia Union host Orlando City in a high-stakes Eastern Conference showdown.How to watch & streamApple TVWhenSaturday, Sept. 26 | 7...
Match Preview | St. Louis CITY SC to Face Red Bull New York for the First Time Ever on Saturday at Sports Illustrated Stadium
St. Louis CITY SC heads east to face Red Bull New York for the first time ever on Saturday, September 26, at Sports Illustrated Stadium. Kickoff is set for 6:30 p.m. CT and will be available on Apple TV. How to Watch Stream: Apple TV Apple TV Talent (English): Jonathan
Matchday 28: Eastern Conference playoff races take center stage
By Ari LiljenwallWith the Audi 2026 MLS Cup Playoffs fast approaching, the stakes continue to rise across the league.Matchday 28 brings another packed slate, highlighted by pivotal Eastern Conference ...
Cannabis Business Red Iris LLC Not Coming To East Grand Forks
(KNOX) -A cannabis business that was approved to open up a shop in East Grand Forks will not end up coming to ...
Why Trump’s Fawning China Welcome Might Be His Biggest Gamble
The president’s embrace of the Chinese dictator isn’t just diplomacy. It’s a political high-wire act.
Lee Health Expands Healthcare Access in Eastern Lee County with New Outpatient Center at The Forum
Residents of eastern Lee County will soon have greater access to healthcare services closer to home with Lee Health at The Forum. Scheduled to open next year, the facility will offer primary care, Lee Convenient Care, and on-site laboratory services, creating a convenient healthcare destination for patients in Lehigh Acres, East Fort Myers, and surrounding […]
Individual health insurance market premiums in Colorado expected to increase about 10%
People in the Grand Junction area will experience a 15.5% increase, while those in the Eastern Plains are on the lower end with a 5.9% increase.
Is metascience being co-opted?
In July, the White House released a report that argued academia is deeply dysfunctional and in need of radical reform.Science: A New Golden Age sets out a litany of problems many academics will recognise: interminable waits for grants; short-term funding rather than support for longer, more ambitious projects; ballooning administrative requirements; pressure to publish, and many more. “The scientific machine is getting bogged down,” it says. At least on the face of it, Science: A New Golden Age is a triumph for the metascience movement, a loose-knit, global group of academics, philanthropists and think tankers that want far more testing and experimentation in how we fund public research and innovation. The report tells US research funders to set up internal metascience units to do just this. But it has also set alarm bells ringing that metascience is being conveniently deployed to help justify the defunding of US universities, which US vice president JD Vance has openly labelled “the enemy.” “Just because you have an issue with your plumbing in your house doesn't mean you light the entire house on fire and burn it to the ground,” said Colette Delawalla, chief executive of Stand Up for Science, a group campaigning against what it says are attacks on scientists by the Trump administration. No one is arguing that academia doesn’t need reform, but there’s debate over how far and how fast the system should be shaken up. Does public R&D need slow and steady evidence-based adjustment, or radical new experiments?One of the key arguments in Science: A New Golden Age is that there’s not enough funding for what it calls “mid-level” science: engineering-heavy projects that require tens of millions of dollars, involve ten to a hundred people, and last around five years. Such a project might develop a brain-computer interface for people with Alzheimer's disease, for example. As such, the US National Science Foundation (NSF) has already announced $1.5 billion to set up so-called X-Labs, effectively new research organisations to pursue breakthroughs in areas such as quantum sensing and new scientific instruments. Funding divertedBut there’s a catch: this money has squeezed NSF budgets for more traditional, fundamental research grants, Science reported in June, likely meaning less cash for university-based scientists. Science: A New Golden Age also makes various swipes at universities, accusing them of extracting overheads from scientists to fund administrative bloat. “We have become dependent on a narrow set of legacy institutions,” it says. The report doesn’t mention it, but the US government is simultaneously seeking greater powers over federal funding, which would allow political appointees at funding agencies to screen or cancel research grants mid-project. The White House is also seeking to slash the NSF’s budget by more than half in 2027, although similar cuts proposed for 2026 were blocked by Congress. Convenient hookThis has worried some that the metascience agenda could be misused as a kind of smokescreen to further weaken universities. James Wilsdon, executive director of the Research on Research Institute at University College London, said that the report contains lots of “interesting ideas” and agrees that in places, academia is a “pretty broken system.” But the risk is that metascience is being deployed as a “convenient hook” to support cuts and a “political land grab” to transfer grant power from scientists to political appointees in US funding agencies.So far, the metascience agenda hasn’t been seized on by radical right parties in Europe. But Wilsdon worries it will cross the Atlantic, politicising research reform efforts and making them more difficult to carry out. The report is already making some in Europe sceptical of the entire idea. “The system is not without flaws, but the metascience discussion is not likely to improve the system but rather to generate munition to undermine it,” said Claes de Vreese, a professor of AI and society at the University of Amsterdam. Peter Thiel protégéOfficially, Science: A New Golden Age has just one named author: Michael Kratsios, the director of the Office of Science and Technology Policy and a former chief of staff to Silicon Valley mogul Peter Thiel. He also served as chief financial officer of Thiel’s Clarium Capital Management. Since the 1990s, Thiel has criticised US universities for moving away from teaching what he views as the classic works of western civilisation, and drifting towards “anti-Western zealotry.” And since 2011, he has offered two-year fellowships of $250,000 to young people to skip or drop out of university, and instead start companies or pursue scientific research. “College can be good for learning about what’s been done before, but it can also discourage you from doing something new,” according to the Thiel Fellowships website. In other areas, the Trump administration has promoted academics with a longstanding interest in metascience. For example, the head of the National Institutes of Health, Jay Bhattacharya, in 2020 co-authored a study arguing the funder backs overly conservative proposals, although he achieved wider prominence as a critic of pandemic lockdowns. Careless talk costs fundingEven before the Trump administration embraced the metascience agenda, some metascientists privately wondered whether they should be careful not to overstate dysfunctions in academia, in case this gets used as ammunition against universities. But others think being cautious with criticism is pointless. After all, last year, the Trump administration sought to cut funding from US universities on an entirely different premise: supposed antisemitism on campus. “I don't think these governments need a technical metascientific excuse to attack the universities, they will want to do so anyway,” said Will Stone, a researcher at Science Works, a new think tank advocating for a “metascience revolution” in the UK. “I think researchers should report what they find, even when the findings may be used to advance policies they disagree with,” echoed Russell Funk, a researcher at the University of Minnesota, who in 2023 co-authored a highly influential paper that argued scientific papers were becoming less disruptive over time. No justificationThat said, Funk thinks that metascientific research certainly doesn’t justify a weakening of universities. Instead, scientists need “time, resources and stability to pursue unfamiliar ideas,” he said. “Taking away those conditions works against the very goal the reforms are supposed to achieve.”The Institute for Progress, a Washington DC-based innovation policy think tank that has championed X-Labs and metascience units, also says that reforms should complement, not supplant, universities. “Unpredictable, unreliable, and reduced federal funding to researchers is destabilising to the very foundations of research and development and is bad,” said Jenn Gustetic, the institute’s director of metascience and R&D policy.Evolution or revolution?This points to a much bigger divide in the metascience community: how far and how fast should public R&D be shaken up? Does it need evolution or revolution? For example, Science: A New Golden Age says the science system relies too heavily on traditional “workhorse” project grants, the type that pay out around $250,000 a year to fund “hypothesis-driven science by small teams on tractable questions.” However, in criticising project grants, the report “decisively picks one side of a debate that is far from settled,” David Hilmer Rex, a metascientist based in Denmark, has written. In June, Pierre Azoulay, a metascientist at the Massachusetts Institute of Technology, defended project grants, saying that the alternative of X-Labs “merits scepticism.”A-B testingOne challenge in metascience is that it’s easier to generate evidence for some types of change than others. Most straightforwardly, research funders can run A-B tests on different ways of awarding money. For example, Germany’s Volkswagen Foundation recently trialled distributed peer review, where applicants rate each other’s proposals, and measured its results against traditional review panels. Distributed peer review made quicker decisions, although awarded money to largely different ideas. However, much of the focus of the metascience movement has been on founding fast-moving and free-acting new research organisations and funders, in contrast to the alleged stodginess of mainstream academia or public innovation grants. A culture of speed and freedom are the animating principles behind Germany’s Sprind or the UK’s Advanced Research and Invention Agency (Aria).Related articlesViewpoint: it's time to experiment with how Europe funds science European researchers sound the alarm that Trump rule changes will hit cooperationHowever, while it’s possible to closely study previously successful bodies, such as the US Defense Advanced Research Projects Agency (Darpa), for historical clues to their secret sauce, it’s impossible to guarantee in advance that the likes of Sprind or Aria will actually work as hoped. But advocates of new organisations say this inherent uncertainly shouldn’t stop us trying. “If we wait for definitive proof that something will work before we try it, I don't know where your proof is coming from,” said Stone. Trade-offsUp until now, experiments in metascience haven’t generally come with hard trade-offs over money. In the US, new ideas such as focused research organisations have often been funded by billionaire philanthropists. In Europe, new innovation agencies such as Sprind and Aria, or the Netherland’s new National Agency for Disruptive Innovation, haven’t needed explicit cuts elsewhere in the research system. But with the $1.5 billion establishment of X-Labs by the NSF, the trade-offs are becoming clearer. Some metascientists privately wonder whether a smaller pilot would have been more appropriate, given that the idea is untested. The Institute for Progress counters that the $1.5 billion X-Labs budget is spread out over a decade, so will account for less than 2% of the NSF’s annual budget. “It’s important to remember that [Darpa] was once an institutional experiment as well. Now it’s one of the most cited innovative funding models in the world,” said Gustetic.As for Europe?The US isn’t the only country placing metascience at the heart of its research strategy. Science: A New Golden Age looks admiringly at the UK, which in 2024 set up a Metascience Unit to scrutinise how it funds research. In Brussels, it’s more of a mixed picture. In 2018, the EU set up the European Innovation Council to funnel grants and equity to start-ups, although it’s sometimes criticised for awarding money too slowly. Recently, the council has started experimenting with challenges, where teams of inventors compete to overcome a technological challenge. The European Commission also wants to experiment with partially randomising grant winners, to cut down on bureaucracy. However, the Commission’s own advisers have said the EU’s own research schemes are too conventional. They want the Commission to establish a new dedicated unit to scrutinise and experiment with funding. But there’s no sign of a such unit emerging in Brussels’ plans for the next Horizon Europe programme, which from 2028 is set to distribute more than €160 billion over seven years. Sam Bogerd, director of breakthrough innovation at the Brussels-based Arq Foundation, an AI-focused think tank that also looks at metascience, says that Europe might have the opposite problem to the US: universities and basic research funding are still reasonably well supported, but there’s not enough experimentation. “We're not taking a close enough look at where this money can achieve the most, and I am worried that the good ideas around metascience will be tainted politically by their association with the Trump administration,” he said. He’s still lobbying for the Commission to set up an experimental unit. But in the meantime, the Arq Foundation plans to do its own research, and is currently hiring two metascience researchers to run the rule over how Brussels spends research funding.
EU science policy wonks debate prospect of stronger ties with Canada
Europe’s research and innovation sector has started asking questions on how European Commission President Ursula von der Leyen’s offer to make Canada “the first associate member of the EU” would actually work in practice, and who will get to shape priorities in a transatlantic relationship that is getting stronger. The Commission says it wants “a new model of association” under which the EU and Canada will aim to develop “a shared space” to face ongoing challenges. “Working in close coordination with our member states and the European Parliament, we will aim to create a new form of partnership that has not existed until now, building the closest imaginable form of association with a partner outside Europe,” a spokesperson told Science|Business.Locked in an escalating trade war with US President Donald Trump, who has repeatedly talked of annexing Canada, Prime Minister Mark Carney has been looking east, but full EU membership was never in play. Taking the floor a day after von der Leyen’s proposal, he agreed to strengthen ties under “an alliance of the future” but reined in enthusiasm on the new label. He also suggested expanding Canada’s involvement in the Erasmus+ student mobility scheme, to which it currently has limited access, and the next iteration of Horizon Europe. Canada joined the present Horizon Europe in 2024, but only contributes to collaborative projects.Neither side has detailed the next practical steps in developing this new relationship. “I think nobody at the moment truly knows how this will work,” said Michael Browne, chief executive and founder of Crowdhelix, a global collaborative network that connects players in research and innovation. “It’s more of a statement of intent for closer collaboration, which requires legislative frameworks and approval processes, which have not started.”Kurt Deketelaere, secretary general of the League of European Research Universities, said von der Leyen’s pitch to Canada is “politically significant, but the legal content still has to be negotiated and constructed.”Mattias Björnmalm, secretary general of the Cesaer university group, agreed that she had only opened “a political door” to Canada, as “associate membership does not come with a predefined set of rights in the EU institutions.”Not only does this status not currently exist as a legal category in the two treaties that set up how the EU functions, but the Commission president cannot unilaterally create a new category of EU membership.According to Deketelaere, Article 217 of the Treaty on the Functioning of the EU, which allows the bloc to make association deals with non-EU countries involving reciprocal rights and duties, is “the most obvious existing legal basis for building a much deeper EU-Canada relationship.”Getting universities involvedNo matter how this new cooperation takes shape, Liviu Matei, who heads the School of Education, Communication and Society at King’s College London, hopes to see universities involved in discussions from an early stage.“Its primary motivations, entirely justifiably, are political and geopolitical,” he said. “In the area of higher education, however, restricting the initiative to political and geopolitical considerations would limit the scope of cooperation and lead to distorted frameworks and counterproductive implementation.”It is all the more important since academic interests on the two sides of the Atlantic are “neither identical nor fully aligned,” Matei added. “This is not insurmountable; it simply requires work to articulate the details of this privileged cooperation, including its governance and funding frameworks, as well as its substantive content in education and research.”Related articlesCanada looks to deepen research and education links with the EUZaharieva hopes for a Horizon Europe deal in 2026Canada might participate in European Research Council schemes, for example, which was not on offer in the present Horizon Europe association agreement. But “there would have to be something in it for the EU,” Browne said. “They don’t want to be funding projects outside of the EU where intellectual property is going to sit outside of the EU. There has to be some kind of transfer of knowledge.”But access to funding will not by itself resolve all the practical difficulties of working together, said Björnmalm. “For researchers and students, these include visas and residence arrangements, recognition of qualifications and study periods, and the conditions for pursuing a research career across borders,” he said. “For universities, there is scope for more predictable access to shared laboratories, computing and research data, and stronger support for joint doctoral training and long-term institutional partnerships.”Linda Doyle, provost and president of Trinity College Dublin, said Europe should strive for the “closest possible expression” of this new political alliance. “If Europe is serious about recovering its voice and its place in the world, it needs to be strongly allied with countries who share its values and its vision for a stable, rules-based, peaceful world.”
Review: DRAGON QUEST XI S: Echoes Of An Elusive Age - Definitive Edition (Switch 2) - Square Enix Needs To Get With The Upgrade Path Program
Well, at least it looks a little nicer
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