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El Paso, Texas high school sports scoreboard: Sept. 8-12, 2026
El Paso, Texas high school sports results for volleyball, football and cross country.
Why a shorter eating window may not mean better metabolic health
In a nationally representative cross-sectional study of 16,973 Korean adults, researchers identified three distinct eating patterns based on the timing and distribution of daily energy intake. Eating later within a shorter daily window was associated with higher odds of metabolic syndrome, elevated blood pressure, triglycerides, and fasting glucose, while frequent grazing showed a mixed metabolic profile.
More Than 5,000 Leaders Across Entertainment, Academia and Public Life Unite to Reject “Genocide” Accusation Against Israel
Boris Johnson, Deborah Lipstadt, Sir Niall Ferguson, Shari Redstone, Steven Pinker, Sherry Lansing, Simon Sebag Montefiore, Chief Rabbi Warren Goldstein, Irwin Cotler, Debra Messing and thousands of others reject the genocide accusation against Israel and warn that it fuels antisemitism
Hawaiian Telcom Unveils Future-Ready Business Fiber Platform Engineered for 10 Gig Connectivity
Hawaiian Telcom announced enhancements to its business fiber internet portfolio, including expanded symmetrical upload and download speeds across Fioptics Business Internet plans and the introduction of Fioptics Advanced WiFi for business customers. Together, these enhancements provide Hawaiʻi businesses with faster, more scalable connectivity backed by a fiber network engineered to support connectivity solutions up to 10 Gig.
Should the Chicago Bears extend D’Andre Swift?
Welcome to SB Nation Reacts, a survey of fans across the NFL. Throughout the year, we ask questions of the most plugged-in Bears fans and fans across the country. D’Andre Swift is in the final year of the three-year, $24 million contract he signed with the Chicago Bears in 2024, and before last season, no […]
COVID-19 cases on the rise across all age groups, local healthcare expert says
Dr. Jason Bowling, the chief epidemiologist at University Health, said there is an increase in COVID-19 cases across all age groups.
Hurricane Lowell forces bank closures across Kauai, parts of Oahu and Maui
All major Hawaii banks closed Kauai branches Tuesday as Hurricane Lowell brought high winds, heavy rain and widespread power outages to the islands.
Oil jumps $1 in early trade after Iran launches missiles at Jordan
Oil prices jumped for the fourth straight session, gaining more than $1 in early trade on Wednesday after Iran launched fresh attacks on U.S. military assets in the Gulf as the war between Washington and Tehran continued to spill out across the region.
COVID-19 infections rise across California as health officials urge vaccinations
California health officials are encouraging residents to stay up to date on COVID-19 vaccinations as infections increase statewide.
Yolo County reports its first West Nile virus death of 2026
Yolo County has reported its first death from West Nile virus this year as health officials say mosquito activity increases across the county and throughout California.
MUSC Health to open new dental clinic in Florence, expand oral care in Pee Dee
MUSC Health is opening a new dental and oral care clinic in Florence that officials say will expand access to dental services across the Pee Dee and help train
Youth sports become big business, putting stress on families and leaving some behind
Roughly 5 million kids are competing for travel or club sports teams that have cropped up across the country. Many benefit from that participation, including some who get college scholarships, but youth travel sports also come with increasing costs and challenges. As Stephanie Sy reports, those trade-offs and concerns are a part of the story that's getting more and more attention.
The 98 Biggest TV Show Flops, Bombs and Misses in the First Half of 2026
(Welcome to the Entertainment Strategy Guy, a newsletter on the entertainment industry and business strategy. I write a weekly Streaming Ratings Report and a bi-weekly strategy column, along with occasional deep dives into other topics, like today’s article. Please subscribe.) In July, I updated my look at how the “streaming bubble” popped since 2023, showing the decline in streaming TV shows over time. But after compiling and analyzing and writing about over one hundred TV show flops in the first half of 2026—I counted 99 “nominees” and there are even more honorable mentions—I couldn’t have told you that the number of shows is going down. When it comes to scripted, English-language TV shows, it feels like we have as many bombs as ever. I don’t keep a specific count, but some streamers probably had as many flops as they’ve ever had.1 That’s right, it’s time for part two of my analysis of the biggest flops, bombs and misses on streaming in the first half of 2026. Two weeks ago, I took a look at films. Today, TV shows. If you want to read the full methodology for how I assemble this list, you can find it at the bottom of this article. In short, this list is… ...scripted and unscripted TV shows,...from the nine major streamers,...in the US (using US-only ratings),...excluding true crime, kids and foreign-language shows,...that got no/poor ratings,...from Jan-2026 to the end of June-2026. Reminder: this article does not represent my personal opinion—many of these shows are great!—but I follow the data, and a miss is a miss and a bomb is a bomb. Also, price matters. If a TV show costs north of $100 million, it needs to get lots and lots of streaming viewership to justify that budget. As with past editions, I ordered this list by streamer, going from best (fewest flops) to worst (the most misses)—taking the size of the flops into consideration—and like the last edition, three or four streamers vied to take the win/loss of having the most flops. (But the actual winner is no surprise.) I try to avoid tooting my own horn too much, but seriously, in just under 5,000 words (including the methodology section) I provide a mostly comprehensive overview of the eight major streamers (Netflix, Disney+, Prime Video, Hulu, HBO Max, Peacock, Paramount+, and Apple TV) for the first half of the year, mentioning most of their hits and all their misses. It summarizes the entire first half of 2026! If you want to support this work, please subscribe. Subscribe Tubi Big Mood Boarders The Freak Brothers Twenty Twenty Six Honorable Mentions: Busted on Bodycam, Deestroying the Pitch, Destination World Cup 2026 I don’t think that Tubi spends all that much making or (mostly) licensing these original TV shows—Big Mood, Boarders and Twenty Twenty Six all come from the UK—but they’re not free and they didn’t chart anywhere. Winner: The Freak Brothers Have you even heard of this show? It’s an animated comedy...that’s on its third season! And Pete Davidson, Woody Harrelson, John Goodman and Tiffany Haddish all provide voice talent for it. Yes, animated shows don’t cost as much as live action shows, but cheap isn’t free! So a show with this level of talent needs to perform better. Disney+ Daredevil: Born Again Star Wars: Maul – Shadow Lord Honorable Mentions: Behind the Attraction, Donna Hay Coastal Celebrations, We Call It Imagineering Disney+ doesn’t make all that many original shows anymore. They had two flops, and one was animated. Their one not-a-miss show, Wonder Man, got just good enough viewership to not be considered a “miss”...but it’s since been cancelled. At this point, Disney has pivoted entirely away from making big budget TV shows for Disney+ to making...almost nothing for Disney+? Sure, Disney’s spending circa 2019-2022 was unsustainable, but now they’re pivoting too far in the other direction. At some point, Disney needs to stop shifting strategies so wildly. Really, Disney should have made fewer shows for Disney+ at launch and the shows they did make at that time needed to be made at more reasonable budgets. And they should adopt that strategy now. Winner: Daredevil: Born Again Daredevil, the Marvel Comics character, is on my personal Mount Rushmore of favorite superheroes, so it pains me to give him the win/loss today, but this show deserves it. I’ll repeat my hot take from last spring: “Based on his popularity, Daredevil should be in movies, and probably ones that cost a lot less than the MCU’s usual price tag. Disney/Bob Iger/Ike Perlmutter (who, based on reporting, made the decision) made a huge mistake selling TV shows to Netflix in the 2010s, thus limiting this character to the small screen. Daredevil could have anchored Marvel’s post-Infinity War plans, and if he did, the MCU would probably be in a better place than it is now.” HBO Max We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… What four streamers had the most misses... HBO’s strong start to 2026… The caveat to Peacock’s turnaround this year... Paramount+’s key man problem… What country isn’t delivering hits for Netflix or Hulu... The cavalcade of stars on a streamer where no one is watching their shows... Across nearly 5,000 words of analysis… And a lot more... ...please subscribe! We can only keep doing this great work with your support. If you’d like to read more about why you should subscribe, please read this article about the Streaming Ratings Report, why it matters, why you need it, and why we cover streaming ratings best.
3 Takeaways From the Latest PISA Test of Reading, Math, and Science
The results show reading performance dropping across the world—and one uniquely troubling U.S. trend.
Haaland double powers Man City to victory over Porto
Erling Haaland scored twice as Manchester City began their Champions League campaign with a 2-0 victory at Porto.This time, though, they got the second goal to kill Porto off as Haaland slotted in Rayan Ait-Nouri's cross for his 59th Champions League goal in 59 games in the competition. kca/iwd/nf
Crossland Construction Lab opens at Bentonville High School
Area schools are working with construction companies to introduce students to industry jobs through construction programs as demand for workers rises. A construction company executive hopes the programs will lead...
Wisconsin Department of Health Services reports increase of measles cases in southwestern Wisconsin
The Wisconsin Department of Health Services announced an increase in measles cases across southwestern Wisconsin on Tuesday.
From farm to table: Edgecombe County effort expands access to fresh, healthy food
An Edgecombe County farm is expanding its efforts to tackle food insecurity and improve access to healthy food across eastern North Carolina.
Mapping the Global Health Landscape: Analysis of Fourteen International Organizations
The global health architecture includes a number of diverse international organizations with different mandates, governance models, financing structures, and operational approaches. This KFF resource looks across a range of variables to provide a descriptive mapping of 14 key global health and related international institutions. It is intended to inform discussions about synergies and coordination, duplication, comparative advantage, shared challenges, and architectural reform.
Pamplin+ transforms undergraduate business curriculum into four-year experiential internship
Launching in fall 2026, Pamplin+ transforms the Pamplin College of Business undergraduate experience through hands-on learning, required internships, mandatory agentic AI coursework, and cross-disciplinary corporate projects.
Supporting small business across North Dakota
ND SBDC State Director Tiffany Ford joins ‘North Dakota Today’ to discuss the organization’s statewide impact
Exclusive: Two of gaming’s biggest names are making a big investment in gaming’s future
The first thing to know about the Nova Games Foundation is that it isn’t about The Game Awards. And it’s not about PlayStation. The ambitious new grant program is the brainchild of Geoff Keighley and Mark Cerny. Keighley is the host of The Game Awards, Summer Game Fest and Opening Night Live. Cerny is a game designer of some 45 years and the lead architect for the PlayStation 4 and 5. But this new thing, which they’re revealing through Game File, isn’t about their day jobs. It’s an unaffiliated, standalone philanthropic project. It’s a bet on the artistic future of video games and a way, they tell me, to give back. “I’m nearing the end of my career,” Cerny recently told me over email. “I’m not done yet, but paying it forward—in the best way possible—is very much on my mind these days,” The Nova Games Foundation is a university-affiliated fellowship program, intended to offer six-figure grants to 20 young game designers each year, potentially for decades to come. It will offer no-strings-attached funding along with mentorship from games industry leaders, a combination intended to aid the development of groundbreaking new games, Cerny and Keighley told me. Nova will begin accepting applications in December, from class of 2026 and 2027 students from 13 affiliated gaming programs at universities in eight countries. The schools working with Nova include the New York University and the University of Southern California in the U.S., along with Abertay University in Scotland, Cnam-Enjmin in France, TH Köln in Germany, and the Royal Melbourne Institute of Technology in Australia, Cerny and Keighley said. The plan: $100,000 per recipient, with about a quarter of Nova fellows eligible for up to $500,000 more for projects that are shaping up particularly well. Payments will be delivered based on development milestones, and recipients will own their games. Nova will help promote the work, and developers will be free to pursue the publishers and platforms of their choice. Nova can help introduce fellows to publishers, but won’t take a cut. “I’ve always wanted to give back, but given my role in the industry, I’ve never felt it appropriate to commercially invest in games,” Keighley told Game File. “I’ve never owned stock in a game company or taken a financial stake in a game. Nova is philanthropy: we aren’t taking equity or looking to recoup the grants. The return we’re hoping for is creative—helping new voices make games and find their footing. “Mark and I have each made multi-million-dollar donations to establish the foundation, and we intend to keep contributing. We hope others will join us.” Cerny and Keighley have already hired an executive director, John Maconga, and a head of grants, recent Game Developers Conference director Ashley Corrigan, to help launch the effort. They’re working to recruit game industry leaders to join the effort. Keighley says “dozens of leading game directors have already expressed interest in contributing their time.” To name one, they’ve already gotten Josef Fares, lead designer from It Takes Two and Spit Fiction studio Hazelight on board with a donation and pledge to help out. “I’m proud to support Nova because it gives the next generation of creators the freedom to explore their creativity and hopefully bring their unique visions to life,” Fares told Game File. A plan forged from a friendship Keighley and Cerny have known each other a long time. It’s been so long, Cerny isn’t even sure exactly when they met. “We travel in much the same circles and I’m sure first intersected in the 90s or early 2000s,“ Cerny said. Keighley thinks it might have been during his stint writing a column about the mid-’90s console 3DO for a gaming magazine while Cerny was working on games with Crystal Dynamics or on Way of the Warrior with Naughty Dog. They became genuine friends about a 10 years ago, Keighley said, as they bonded over a shared love of games and a hope to improve the industry. “About a decade ago, we started having dinner a few times a year in LA,” Keighley said. “Just to catch up on life and the industry. Those conversations continued over Zoom during COVID. Nova grew out of that friendship and a question we kept coming back to: ‘What could we do to help the next generation of game directors get started?’” Keighley credits Cerny with the idea to figure out a way to put their money and time back into the industry. At one of those dinners, Keighley proposed the idea of a fellowship program. He’d recalled applying for a Rhodes Scholarship when he was younger. “Spoiler: I didn’t get it,” he said. He’d admired the MacArthur Foundation’s so-called “genius grants.” He liked these kinds of programs that recognized people’s talents and gave them the financial boost and the freedom to realize their potential. With Cerny, he had pondered what a game industry version of that could be. Keighley liked the idea of centering the fellowship on students, drawing inspiration from the accomplishments of Jenova Chen, the USC game design graduate who went on to lead the creation of gently moving, ambitious games such as Flower and Journey. Keighley also thought it could be useful to help promising graduates bridge the transition from student to professional. “Joining an established studio isn’t always possible—especially in today’s market—and even then, it isn’t the right path for everyone,” Keighley said. A fellowship, he realized, could give “graduates the time, resources and guidance to pursue a game of their own and not worry about the commercial viability.” As the idea took shape, Cerny also saw an opportunity to enable more games of a certain type: “The target with the grants is games as an artistic medium,” Cerny told me. “We like to say games with ‘artistic, literary and societal value.’” He added: “I’m a pretty big gamer myself, though I tend to gravitate towards the smaller and more unique or artistic titles, games like Neva, Abzu, Gorogoa, Stray or Outer Wilds. I was just playing and Roger on a flight to Japan, and was getting misty eyed to a degree that I was concerned that a flight attendant would ask me if I was OK. “So one fun benefit here is the games that will come out of the Nova Games Foundation – I can’t wait to play them myself.” Cerny believes it will also be useful for Nova fellows to hone their craft and team leadership skills. “We are looking for the next generation of visionaries,” he said. “The trick is that they will also need to have the executive function necessary to drive a small project to completion.” Game File is a reader-supported publication. To receive new posts and support my reporting, please consider becoming a free or paid subscriber. Subscribe Going big with this Keighley and Cerny may have started Nova and may be the ones primarily backing it right now, but they’re dreaming of something that goes beyond them. “Mark and I may have helped get it started, but one of our measures of success is that Nova grows into something the entire games industry feels a sense of ownership in,” Keighley said. “Our ambition is to build a lasting endowment supported by people and companies across the industry, and an equally broad community of creators willing to give their time and experience to the next generation.” The industry has a lot of knowledge that it can pass to the next generation, Keighley said: “Nova can hopefully become a way to connect that generosity with talented young creators at the moment when it can make the biggest difference.” Cerny, who told me he believes Nova can mature “over the next 10 or 20 years,” sees an opportunity to give generations of game makers momentum. “The industry has changed immeasurably since I started in games in 1982,” he said. “These graduates have talent, training and tools that outclass what we had back in the day by an astonishing amount. But they face a tough road ahead getting traction in the industry, and many could benefit from our support. We want to be there to give it to them.” “There’s a personal side to this, too,” Keighley said. “I don’t have children, and I’ve spent a lot of time thinking about what I can do for future generations. Games have been my entire career. I’ve been incredibly fortunate, and helping someone else build a life in this industry feels like a meaningful way to give back.” Cerny’s oeuvre dates back to Marble Madness and Sonic the Hedgehog 2. He has stood on stage multiple times to reveal the future of PlayStation hardware. He’s been an executive producer for a string of modern PlayStation classics such as The Last Guardian and Marvel’s Spider-Man. Nevertheless, of Nova, he said, “It’s certainly not like anything I’ve done before.” Nova Foundation applications will be due in December and the first wave of fellows will be announced in March 2027. A full list of participating universities and steps students and recent graduates can take to apply to become a Nova Fellow is forthcoming.
Scripps Sports Expands Nashville Predators Television Coverage to Seven Additional Markets Across Tennessee, Kentucky and Alabama
Multi-Year Media Rights Agreement Brings Predators Hockey to Broader Regional Audience With Comprehensive Broadcast Package
Mysterious elk deaths in Nevada could offer clues about health of herds across the West
An unusual pattern of springtime elk deaths for more than a decade in northern Nevada has scientists searching for answers. What they find could shed light on broader questions about wildlife health across the West.
Mysterious elk deaths in Nevada could offer clues about health of herds across the West
An unusual pattern of springtime elk deaths for more than a decade in northern Nevada has scientists searching for answers. What they find could shed light on broader questions about wildlife health across the West.
Scientists Keep Finding the Same Mysterious Beat Across the Animal Kingdom, From Fireflies to Sea Lions
From fireflies to mammals, evolution may have tuned communication to the rhythm of neurons.
Health: The Fight For The Health Of 9/11 First Responders
A quarter century after 9/11, the health of those who responded to the attacks continues to be affected.Some 3,000 people died across three locations that day. An estimated 400,000 people were exposed to toxic contaminants and risked physical injury in the hours and days that followed. That’s according to data from the Centers for Disease Control and Prevention.Since the dust and debris have settled, more than 96,000 have been diagnosed with physical and mental health conditions related to 9/11.In 2010, President Barack Obama signed the James Zadroga 9/11 Health and Compensation Act, establishing the World Trade Center Health Program and reopening the 9/11 Victims Compensation Fund. Today, more than 150,000 people are enrolled in the program.But that program wouldn’t exist without the advocacy of survivors and first responders who put their bodies and lives on the line following the attacks. How did that fight for care unfold?For more information about the Rutgers WTC Health Program, click here. And to learn more about applying, click here.Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a.
As WTC steel beam makes stop in D.C., Trump pledges to never forget 9/11 victims
Trump spoke as part of a Steel Across America tour that has been traveling the country with a salvaged beam from the World Trade Center
As WTC steel beam makes stop in D.C., Trump pledges to never forget 9/11 victims
Trump spoke as part of a Steel Across America tour that has been traveling the country with a salvaged beam from the World Trade Center
As WTC steel beam makes stop in D.C., Trump pledges to never forget 9/11 victims
Trump spoke as part of a Steel Across America tour that has been traveling the country with a salvaged beam from the World Trade Center
Senior Health Fair set for Sept. 11 in Flower Mound - Cross Timbers Gazette | Southern Denton County | Flower Mound
Southern Denton County residents age 50 and older can connect with dozens of health and wellness resources during the 2026 Senior Health Fair this Friday, Sept. 11, in Flower Mound. The Flower Mound Seniors in Motion Auxiliary will host the annual event from 9 a.m. to noon at the Flower Mound Senior Center. Admission is […]
Fernandes receives second Ballon d'Or nomination
Manchester United and Portugal attacking midfielder Bruno Fernandes has been named in the 30-player shortlist for the 2026 Ballon d'Or. The 32-year-old made 37 appearances across all competitions last season, scoring nine goals and contributing 22 assists, as Manchester United secured Champions League football for 2026-27.
Live Results: New Hampshire midterm primaries
The race to replace retiring three-term Democratic Sen. Jeanne Shaheen is one of a handful across the country that could determine control of the U.S. Senate for the second half of President Donald Trump’s final term.
Current events: Scientists keep close eye on Atlantic Ocean changes
The year is 2060. London shudders through months of Nordic winter freezes. Across northern Europe, oak and beech forests wither under severe frost and drought, while cereal yields collapse from temperatures ...
Haaland receives sixth Ballon d'Or nomination
Manchester City and Norway striker Erling Haaland has been named in the 30-player shortlist for the 2026 Ballon d'Or. The 26-year-old made 52 appearances across all competitions last season, scoring 38 goals and contributing nine assists, as Manchester City lifted the FA Cup and Carabao Cup. Haaland's new team-mate Ayyoub Bouaddi has also been nominated for the Men's Young Talent of the Year award.
Holman Assumes Full Ownership of ARIZA, Unifying 30-Year Mexico Business Under the Holman Brand
MOUNT LAUREL, N.J., September 08, 2026--Holman Assumes Full Ownership of ARIZA; the acquisition delivers a seamless fleet leasing and management solution for customers across North America.
New report finds little short-term health risk from air pollutants in South Portland, Portland
Six years of air sampling found benzene levels above state guidelines at one location and elevated acrolein levels across the study area.
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
Kamin Science Center using multi-day closure to refresh exhibits on all floors
Officials say the museum is using the mid-week closure to refresh and maintain exhibits and visitor experience across all five floors.
Seiche Launches Marine Science And Technology Department With Three New Leaders
Seiche has established a Marine Science & Technology Department uniting marine mammal specialists, acousticians, and engineers under three new department heads. The move expands the company's scientific and technical capabilities across offshore wind, renewable energy, and broader marine environmental monitoring.
Florida IAM Members Focus on Political Mobilization at Fall Conference
The IAM's Florida State Council recently held its fall conference, bringing together union leaders and delegates to focus on political education, voter mobilization, and strengthening the voice of working families across the state. Led by President Mike Phillips, the conference emphasized the importance of supporting pro-labor candidates and increasing member participation in the political process.
A word with a woman who’s trying to pull off a crossbody phone strap
The elder millennial experience.
LMH Health announces participation in Astra Health to expand access, improve care and reduce healthcare costs
We are pleased to announce that LMH Health is one of five independent Kansas health systems joining together to form Astra Health, a new regional healthcare collaboration designed to improve patient care, strengthen access to specialty services, and deliver more affordable healthcare options for employers and communities across Kansas. By working together, participating health systems […]
DeWitt’s Crossroads Business Park gets ready for growth
DEWITT, Iowa – Community leaders and development partners recently celebrated the groundbreaking of five regional water detention ponds in an expansion of the Crossroads Business Park, marking a major milestone in preparing the site for future industrial growth. The project is the first phase of infrastructure improvements that will make approximately 125 acres of development […]
Moreno calls to end data center subsidies
Pushback against data centers has grown across the country, including in Ohio.
‘Plastic pollution hotspots’ spawn a public health crisis across Latin America
Since China banned the import of plastic waste in 2018, plastic pollution has been having a growing impact on the people and ecosystems of Latin America. As the region imports an increasing amount of the world’s used and discarded plastic, new research shows that waste infrastructure in many countries is already buckling under the strain […]
Sinclair's Criminally Obsessed to Present "Maternal Mental Health: How the Lindsay Clancy Trial Could Change Treatment" National Town Hall to Air on September 9
BALTIMORE – September 8, 2026 – Sinclair today announced a national town hall examining maternal mental health and the questions surrounding diagnosis, treatment and intervention that have been brought into focus by the Lindsay Clancy trial. Maternal Mental Health: How the Lindsay Clancy Trial Could Change Treatment will stream September 9 across Sinclair’s television station...
Scientists confirm Newton’s gravity law
Gravity has survived its largest-scale test yet, holding up across distances of up to 230 megaparsecs, or about 750 million light-years. University of Pennsylvania physicists found that the force weakens with distance almost exactly as Newton’s equations predict, a relationship later incorporated into Einstein’s theory of general relativity. Galaxies and galaxy clusters move faster than...
Qualderm and Parakeet Health Partner to Expand Patient Access Across National Dermatology Network
/PRNewswire/ -- Parakeet Health, a healthcare AI company that is transforming patient engagement at enterprise scale, and Qualderm, a management services...
Qualderm and Parakeet Health Partner to Expand Patient Access Across National Dermatology Network
Parakeet Health, a healthcare AI company that is transforming patient engagement at enterprise scale, and Qualderm, a management services organization for a national physician-led skin care network, today announced a collaboration to expand patient access, strengthen care continuity and reconnect patients following cancellations, missed visits, and overdue follow-ups.
Midterm elections shaping up as big business for gamblers in the rough and rowdy world of prediction markets
“This is a troubling trend that election administrators across the nation must deal with,” said Jared DeMarinis of the Maryland State Board of Elections.
Former Iowa Football Stars Gear Up For 2026 NFL Season
The NFL is back tomorrow, and there's going to be plenty of Hawkeyes to follow across the Week 1 slate.
Tour industry protests over Taiwan’s new mainland China travel registration rules
KMT politicians accuse ruling DPP of turning cross-strait exchanges into an election issue ahead of year-end local polls.
Bausch Health and YUN Announce Expansion to Mexico and Across Additional EMEA Markets
/PRNewswire/ -- Bausch Health Companies Inc. (NYSE: BHC)(TSX: BHC), a global, diversified pharmaceutical company, and YUN, a Belgian innovator in pioneering...
Blackbird Health Expands into Maryland, Bringing Pediatric Mental Health Care to Frederick and Gaithersburg
Blackbird Health, a leading provider of pediatric mental health care, today announced its expansion into Maryland with new locations in Frederick and Gaithersburg, bringing families across the region greater access to comprehensive mental health services for children, teens, and young adults.
Trump's plan to pay stay-at-home parents is a political play: Paula Scanlan
The Trump administration is drafting a plan to pay married stay-at-home parents up to $9,000 per child annually. Paula Scanlan reacts to the proposal as child care costs continue to rise across the United States.
In Her Own Words: Jen Oon, digital audio pioneer and early podcast adapter
Jen Oon, SVP of Sales at DAX US, shares how curiosity and relationships shaped her career across Spotify, Pandora, and digital audio.
On 988 Day, Vibrant Emotional Health Reminds Everyone: With 988 Reasons to Reach Out, Your Reason is Reason Enough
Today, September 8 (9/8), Vibrant Emotional Health (Vibrant), the nonprofit administrator of the 988 Suicide & Crisis Lifeline, joins the Substance Abuse and Mental Health Services Administration (SAMHSA) and communities across the country in recognizing 988 Day, a national day of awareness led by SAMHSA to highlight the 988 Suicide & Crisis Lifeline and the importance of making mental health support accessible to everyone.
Milwaukee Wheelchair lacrosse team looks ahead to nationals
The Milwaukee Eagles partner with Marquette University's men's lacrosse team.
Bob Brooks releases first TV ad of the general campaign
Brooks, a Democrat, has garnered support across the party's ideological spectrum, including Gov. Josh Shapiro and U.S. Sen. Bernie Sanders.
Redside Foundation provides mental health assistance to the West's outdoor guides
The Idaho-based nonprofit provides mental health and other services to river, hunting and wilderness guides in states like Wyoming, Montana and Colorado, writes guest columnist Chuck Malloy.
‘You are not a bad mother’: transforming women’s mental health care during pregnancy and after childbirth in Armenia
The arrival of a baby is often seen as one of life’s most joyful moments. Yet behind the expectation of happy motherhood, some women experience anxiety, depression, fear or emotional distress – feelings that can remain hidden behind the pressure to be “a good mother”. In Armenia, a woman’s mental health during the perinatal period is still too often overshadowed by the focus on physical health. This gap was spotted by the Kanani Social-Prsychological Centre NGO, which used EU support to make mental wellbeing part of maternity care across Armenia. During the final months of her second pregnancy Lilit (28) was full of fears. Her
Emily Austin Keeps Finding Ways to Become One of Sports’ Most Talked-About Personalities
Emily Austin has figured out something most people in sports media spend years trying to learn. People remember her. The sports broadcaster and personality continues to build an audience across sports, entertainment and social media. Most recently, Austin made headlines after discussing a potential FIFA World Cup event appearance in New York. She has also…
Israel records one of OECD’s steepest declines in reading, math and science scores
Israeli 15-year-olds lost 38 points in reading, 25 in math and 23 in science since 2022, leaving the country below the OECD average in every field; nearly 3 in 10 now lack basic proficiency across all three
Israeli students plunge to historic lows in reading, math and science
International PISA results reveal the steepest decline in Israel's history across literacy fields, erasing 15 years of improvement. The troubling implication:
Sudan health system faces collapse, Doctors Without Borders says
Sudan's healthcare system is on the brink of collapse as cuts to aid funding force clinics and outpatient facilities to close across the war-torn country, Doctors Without Borders (MSF) said. The organ...
25 years ago, a NASA astronaut captured this haunting photo of the 9/11 attacks
During the Sept. 11 attacks, NASA astronaut Frank Culbertson — the only American not on Earth at the time — snapped a "sobering" shot of smoke pouring across New York City as the second tower fell.
Parties across continents launch dialogue in Seoul as politics fractures, challenges converge
Political parties divided by geography and ideology came together in Seoul on Monday around a shared premise: Even as politics grows more fragmented and polariz
What Farage’s oyster etiquette says about his politics
When it comes to fish, Reform is across the mores
AXA scales governed AI infrastructure across global operations
The insurer's vendor-agnostic hub is already live in five entities, with AXA XL among those building claims and email applications
Perilla frutescens Benefits: Effects on Allergy, Inflammation, Immunity, and Gut Health
Perilla frutescens contains phenolic acids, flavonoids, and other bioactive compounds that show anti-allergic, immunomodulatory, anti-inflammatory, and gut-protective effects across laboratory and animal studies. Limited human evidence, including a small randomized trial of rosmarinic-acid-enriched Perilla extract for seasonal allergic rhinoconjunctivitis, is promising, but larger standardized clinical trials are needed.
Military and intelligence officials discuss smaller presence in the Middle East as US looks for another post-9/11 strategy
In offices across the military and in the intelligence community, there have been recent quiet discussions about cutting the number of people and facilities typically stationed in the Middle East if the Trump administration succeeds in ending the Iran conflict, six sources say.
Adventist Health Launches Epic System with Expanded AI Integration
ROSEVILLE, CA — Adventist Health has announced that they have completed the largest technology implementation in its history, connecting all 27 hospitals and more than 440 clinics across California, Oregon, and Hawaii through a single electronic health record system. The health system went live with Epic on August 30, marking what Adventist Health describes as […]
Where Is the UEFA Champions League 2026?
The 2026 UEFA Champions League final was held at the Puskás Aréna in Budapest, Hungary, on May 30, 2026. Paris Saint-Germain faced Arsenal in the final, with PSG winning the trophy.The new 2026–27 UEFA Champions League season is different because its matches are being played across Europe. The 36 teams in the league phase play […] The post Where Is the UEFA Champions League 2026? appeared first on HEAVY.
‘We will stand together’: Power of unions grows in Central Valley’s political world
While laborers across the U.S. are enjoying the three-day weekend, the work isn’t done yet.
Arkansas regulators approve Blue Cross, Cambia Health affiliation
The Arkansas Insurance Department has approved a strategic affiliation between Arkansas Blue Cross and Blue Shield and Cambia Health Solutions. The affiliation will unify operations and enable the organizations to...
Why Scientists Asked More Than 1,000 People to Bury Their Underwear to Study Soil Biodiversity Across Switzerland
More than 1,000 volunteers buried cotton underwear across Switzerland to help scientists study soil biodiversity and biological activity.
WHO South-East Asia Region recognizes major public health achievements across Member States
The World Health Organization (WHO) South-East Asia Region today celebrated major public health achievements by Member States, highlighting important milestones in disease elimination, maternal, newborn and child health, immunization, and the prevention and management of noncommunicable diseases. The awards were presented by the WHO Director-General, Dr Tedros Adhanom Ghebreyesus, to Ministers of Health or Heads of Delegation during the Seventy-ninth Session of the WHO Regional Committee for South-East Asia. Three major disease elimination milestones were celebrated. Timor-Leste was felicitated for achieving WHO validation for the elimination of trachoma as a public health problem. With Timor-Leste’s achievement, the South-East Asia Region has achieved the global target of eliminating trachoma as a public health problem.
Tate & Lyle strengthens climate ambition with updated science-based targets to reduce greenhouse gas emissions
Tate & Lyle PLC (Tate & Lyle), a global leader in ingredient solutions for healthier food and beverages, announced updated science-based targets to reduce greenhouse gas emissions (GHG) across its operations and supply chain. The new targets, which have been validated by the Science Based Targets initiative (SBTi) as consistent with reductions required to limit global warming to 1.5°C above pre-industrial levels, apply to Tate & Lyle’s expanded global footprint and supply chain following i...
Health Ministers of WHO South-East Asia Region adopt Dili Declaration to advance equity in specialized care
Health Ministers of the WHO South-East Asia Region today adopted the Dili Declaration on Human Resources for Health: Equity in Specialized Care, committing to strengthen the health workforce and ensure that all people, including those living in rural, remote and underserved areas, have access to quality specialized health care. The Declaration, adopted at the Seventy-ninth Session of the WHO Regional Committee for South-East Asia, recognizes that while access to quality specialized care is critical to achieving universal health coverage, it is far too often limited for those most in need. While the Region has made major gains in expanding its health workforce, significant challenges remain in ensuring equitable access to specialists. Shortages persist across many specialties. Moreover, specialists are often concentrated in urban centers, tertiary and private-sector facilities, leaving rural, remote, poor and underserved populations with limited access to essential specialized services.
Man arrested after alleged attack on Amy Acton; candidates across Ohio denounce political violence
Patrick Havas, 38, faces charges after Canfield Fair incident as candidates across Ohio denounce political violence
Political candidates across country attend Labor Day events
PORTLAND, Maine — Troy Jackson was a longtime labor activist and logger before he unexpectedly became the Democratic nominee for U.S. Senate in Maine. On Monday, he returned to a
Small businesses across Pittsburgh area still feeling effects of recent severe weather
Many small businesses are still feeling the impact of last week's severe weather.
Pfaff tells ‘UpFront’ Dems must focus on ‘bread and butter’ issues to win in November
State Sen. Brad Pfaff says Democrats must focus on "bread and butter affordability issues" in order to unite and win in November as he hosted numerous candidates at his annual corn roast at the La Crosse County Fairgrounds.
Stillwater middle schooler places in national Top 300 for young scientists
A middle schooler from Stillwater beat out nearly 2,000 middle school students across the country to win a national STEM award.
🌟 Champions League: 5 talking points from matchday 1
It’s finally back!The Champions League returns this week for the 2026-2027 season!Tuesday, Wednesday and Thursday: the first 18 fixtures of this new edition will be played across three days, with fi...
National high school football rankings: Upsets reshape USA TODAY Sports Super 50
Check the current 2026 season records for top high school football programs across every state in the country.
Federal Rural Health Transformation Program invests $120 million in Indiana
The Trump Administration is investing $120 million to expand healthcare services across rural Indiana.
A Solar Storm Knocked GPS Off by 33 Feet Across the US and Scientists Had Never Seen This Kind of Disruption
The event exposed a hidden weakness in systems that depend on precise positioning.
High Impact Awards Announces 2026 Winners Across Four Categories in Partnership With USA TODAY
Los Angeles, CA, Sept. 07, 2026 (GLOBE NEWSWIRE) -- USA TODAY has started revealing its High Impact Awards , recognizing leaders whose work is m...
African Bizav Strives for Greater Market Opportunity
Industry group presses for regulatory progress and continuity across the continent
Sports Illustrated lists Seahawks as "winners" going into 2026
The Seahawks made the necessary moves in the offseason to come away as winners prior to Week 1, despite much competition existing across the NFL.
Business Monday: Kaʻū farmers grapple with losses of trees, crops and infrastructure from Hurricane Lala
According to the Hawaiʻi Farmers Union, Hurricane Lala has caused more than $3 million in reported losses across 79 types of farms.
Political leaders speak out after man charged with assault at Amy Acton campaign event
Political leaders from across the country spoke out to condemn political violence after a man was charged with assault at an Amy Acton campaign event near Youngstown on Sunday.
Why is far-right AfD’s state victory significant and what might happen next in German politics?
Aftershocks of party’s win in Saxony-Anhalt will ripple across Germany, with two more state elections this month
Russia and North Korea open the first road link across shared border
A bridge will allow up to 300 vehicles a day to pass through a newly built border crossing point
Russia and North Korea open the first road link across shared border
A bridge will allow up to 300 vehicles a day to pass through a newly built border crossing point
How our global UBS AI Expert Symposium moves the business forward
The UBS AI Expert Symposium 2026 brought together AI practitioners across nine global locations to share expertise, explore real-world use cases and accelerate AI adoption across the firm.
Why the iPhone is about to get more expensive
Soaring RAM costs are driving up prices across the tech industry. It may take years to settle down.