SCROLL NEWS / DISCOVERY
Search headlines
Find the stories shaping the conversation.
Results for " poll " 2,429 found 🔀 AI-powered Shuffle
New KFF Tracking Poll on Health Information and Trust Finds One in Three Adults Have Used AI Chatbots for Health Advice — The Monitor
KFF's latest Tracking Poll finds that one-third of the public report using AI chatbots for health information and advice in the past year. And a federal judge suspended, for now, the appointments of thirteen members of ACIP, halting a scheduled meeting and staying recent, widely debated, changes to the childhood vaccine schedule.
Rock Island Entertainment Venue Nominated In USA Today 10 Best Poll
WOC Newstalk 1420 is the Quad Cities place to talk! WOC is also the Quad Cities home for Iowa sports with a full slate of Iowa football and basketball games.
WHO is now a Green Climate Fund accredited entity
The Santiago de Chile Declaration calls for urgent, coordinated action to reduce air pollution and advance environmental justice across Latin America and the Caribbean.
Poll: Vote for the Blue FCU Top Fort Collins-area Girls Winter Athlete
Vote for the top girls winter athlete. Nominees are from Liberty Common wrestling, Fossil/Wellington swim and Fort Collins/Windsor/Timnath basketball.
Poll: Most Americans say U.S. military action against Iran has gone too far
About 59% of Americans say U.S. military action in Iran has been excessive.
Fox News Poll: Voters oppose action in Iran but give US military positive marks
A new poll finds 58% of voters oppose U.S. military action in Iran, while Trump's disapproval rating hits a second-term high of 59%, the survey shows.
Global Chemicals Science Panel Fails to Launch After Chaotic First Meeting - Center for International Environmental Law
Global chemicals science panel stalls after chaotic first meeting in Geneva, exposing political obstruction and delays in tackling toxic pollution.
Monumental Sports & Entertainment Unveils The Blueprint Studios At Capital One Arena
As part of the ongoing Capital One Arena transformation, Monumental Sports & Entertainment (MSE) unveiled renderings for The Blueprint Studios, a new
Glyphosate: A story of science, risk, and nuance
In the summer of 2014, a California groundskeeper named Dewayne Johnson started noticing patches of raw, weeping skin spreading across his body. He had spent years applying Roundup, Monsanto’s glyphosate-based herbicide, for a school district, sometimes drenched in it when equipment malfunctioned. By 2014, he had a diagnosis: non-Hodgkin’s lymphoma. In 2018, a jury awarded him $289 million in damages, later reduced on appeal. Tens of thousands of lawsuits followed. The story hasn’t quieted down. It’s all over the internet, swinging between “this will kill you, buy organic” and “relax, you’re fear-mongering.” Some of that recent chatter stems from an Executive Order protecting glyphosate and its production, which set off intense infighting within the MAHA movement. Some of it reflects a deeper truth: Americans genuinely care about harmful chemicals in their environment (see poll below). And the conversation isn’t going anywhere, with a Supreme Court case involving Monsanto set for this April. Glyphosate (the active ingredient in Roundup) is one of the most widely used herbicides in the world. But does glyphosate cause cancer? And how much exposure is actually risky? With so much mistrust in institutions and corporations (and some genuine conflicts of interest), making sense of the actual scientific evidence is genuinely hard. Here is a translation of what the scientific evidence actually says. Does glyphosate cause harm? Glyphosate is an herbicide that kills most plants it contacts rather than targeting specific species. It works by blocking an enzyme pathway (EPSPS) that plants and many microorganisms need to produce essential amino acids. Without those amino acids, the plant can’t grow and dies. Glyphosate was first developed by Monsanto in the 1970s and became ubiquitous after the company introduced “Roundup Ready” crops in the 1990s. In 2024, Bayer removed glyphosate from residential Roundup-branded products due to litigation pressure. But today it is still the most widely used herbicide in the world. Farmers also discovered they could spray it directly on crops like oats, lentils, beans, and peas just before harvest to dry them out faster and make harvesting easier. Because of its widespread use, it’s obviously really important to understand if it’s harmful to humans. The key principle: The dose makes the poison The most important concept in toxicology is that “the dose makes the poison.” Sixteenth-century physician Paracelsus articulated what remains the foundational principle of toxicology: sola dosis facit venenum. Water will kill you if you drink enough of it. Aspirin saves lives at 81 milligrams and causes internal bleeding at higher chronic doses. So, at what dose is glyphosate poisonous? The LD50 in rats (the dose that kills half the test animals) is around 5,600 mg/kg body weight. Table salt is roughly 3,000 mg/kg. By that classic measure, glyphosate is less acutely toxic than salt. But some people are exposed to a lot of glyphosate through their work. And among the general public, there are many questions about low-dose, cumulative exposure from multiple sources over long periods. Does glyphosate cause health problems? Cancer Correlation maps are striking, with one analysis finding that 60% of counties that spray the most glyphosate have non-Hodgkin’s lymphoma rates above the national average. But correlation alone doesn’t establish cause, which is why animal and human studies matter. In animals: Rat studies are typically what most fear is rooted in, but most people don’t know the study details on the dosage given to rats. A pooled analysis of the 13 most rigorous rat studies found evidence that very high doses, around 55,000 times greater than typical food residue exposure, can cause certain cancers. In humans: One of the strongest studies followed 55,000 herbicide users over 20 years and found no overall increased cancer risk. There was one signal: among those with the highest use, rates of acute myeloid leukemia (AML) appeared elevated. A broader meta-analysis of 18 human studies also found no overall cancer risk, though a separate meta-analysis focused specifically on non-Hodgkin lymphoma found that people with high cumulative glyphosate exposure faced a 41% higher relative risk compared to those with low or no exposure. These human studies are observational studies (randomized controlled trials would be unethical), and meta-analyses are only as reliable as the studies they pool. But the story seems consistent: at very high exposure levels, there may be some cancer risk. But that’s about as far as the science currently takes us. Emerging research: gut and reproductive health Gut: Because glyphosate targets a pathway that exists in some gut bacteria, scientists have questioned whether it could affect the microbiome. In mice, a 2023 University of Iowa study found that glyphosate altered gut bacterial composition and raised markers of intestinal inflammation. A 2024 systematic review found similar patterns: disrupted gut bacteria and problems with the mucus layer that protects the intestinal wall in mice. Whether this translates to humans is an open question. The human gut is highly variable and resistant, and we don't yet have strong studies confirming the same effects in people. Reproductive health: Animal studies have found that glyphosate-based herbicides can interfere with reproductive hormones, including disrupting egg cell development in mice and reducing the number of eggs available in sheep’s ovaries. However, the doses used in these experiments were high, so it’s not yet clear whether the same effects would occur in humans. On the human side, a 2021 pilot study led by Mount Sinai researchers tested urine samples from pregnant women across the U.S. and found glyphosate in 95% of them. The study also found a possible connection between higher glyphosate exposure during pregnancy and a subtle physical difference measured in female newborns. That said, some connections weren’t statistically reliable and this was a small study. The researchers themselves said more and larger studies are needed before drawing firm conclusions. What do regulators say about glyphosate safety? In 2015, the International Agency for Research on Cancer (IARC), part of the World Health Organization, classified glyphosate as "probably carcinogenic to humans" (Group 2A). The classification is worth taking seriously. But, there’s an important distinction: IARC classifies hazard, meaning the potential to cause harm under some conditions. It does not assess risk, which accounts for actual exposure levels and the real-world probability of harm. The U.S. EPA, the European Food Safety Authority, Health Canada, and regulatory agencies in Australia and Japan have all concluded that glyphosate is “unlikely to be carcinogenic to humans” at realistic exposure levels. They’re asking a different question: given how much of this people actually encounter, what is the probability of harm? Your actual exposure is what determines your actual risk. What does glyphosate mean for your daily life? At the grocery store: Food residues are small. The EPA’s acceptable daily intake is 1.75 mg/kg of body weight per day. To hit that threshold from oatmeal alone, a 150-pound adult would need to eat roughly 50 pounds of oats every day. But this calculation addresses only one pathway (food), and we don’t yet have robust tools to measure people’s actual total exposure. If reducing exposure matters to you, organic certification prohibits synthetic herbicides, and organic oat products generally test at lower or undetectable levels. Either way, a diet rich in whole grains, conventional or organic, is far better for your health than one that omits them out of fear of residues. On the farm: Occupational exposure is orders of magnitude higher than consumer exposure. Farmers and farm workers who mix, load, and apply glyphosate-based herbicides, especially without protective equipment, face meaningfully different risk profiles. Proper PPE isn’t optional. Integrated weed management strategies that rotate chemical modes of action are also worth taking seriously, both for health and for long-term effectiveness. If you live near a farm: Spray drift is real. Concentrations near field edges can spike during and after application, particularly on windy days. This is an area where I think public health could really step up and empower rural communities with buffer zones, rather than placing the onus on individuals. But for now, knowing your local agricultural calendar and keeping windows closed during application are the first steps. Bottom line Dewayne Johnson was exposed to glyphosate at levels most people will never encounter, and a jury decided he deserved compensation. That outcome is not evidence that the oatmeal in your pantry is dangerous. But it is a reminder that the dose, the context, and the person doing the exposing all matter enormously. Glyphosate is a chemical tool with benefits, trade-offs, and genuine open scientific questions. Learning to hold that complexity without collapsing into panic or dismissal is, honestly, one of the most useful and hardest things to do in navigating modern health science. Love, YLE Your Local Epidemiologist (YLE) is founded and operated by Dr. Katelyn Jetelina, MPH PhD—an epidemiologist, wife, and mom of two little girls. Hannah Totte, MPH, is an epidemiologist and YLE Community Manager. YLE reaches more than 425,000 people in over 132 countries with one goal: “Translate” the ever-evolving public health science so that people will be well-equipped to make evidence-based decisions. This newsletter is free to everyone, thanks to the generous support of fellow YLE community members. To support the effort, subscribe or upgrade below: Subscribe
This Week in Politics: Developments in the U.S. and Iran War
The U.S. war with Iran rages on and continues to draw mounting public opposition and to induce harsh economic impacts. The conflict has prompted substantial blowback for the Trump administration. A recent poll from Quinnipiac University found that a majority (53%) of U.S. voters disapproved of U.S. military action against Iran, with a larger percentage...
U.S. Medicine, Science Facing An Online Misinformation Siege, Poll Concludes
By Dennis Thompson HealthDay ReporterWEDNESDAY, March 25, 2026 (HealthDay News) — Americans are trapped in a ruthless social media spin cycle of viral misinformation regarding science and medicine, with many actively contributing to the problem, a new Harris Poll has found. People have come to ...
ICE agents have been deployed to airports. Are the polls next?
The high-profile deployment of Immigration and Customs Enforcement agents to airports has renewed support on the right and fear on the left about the possibility of ICE going to the polls in November.
Poll: 1 in 3 Adults Are Turning to AI Chatbots for Health Information, Equaling the Share Who Use Social Media for Health
About a third (32%) of adults nationally say they have turned to artificial intelligence (AI) chatbots in the past year for health information, a new KFF Tracking Poll on Health Information and Trust finds. Most who turned to AI for health information say they were in search of quick and immediate advice, though challenges affording and accessing health care also play a role, particularly for younger adults.
KFF Tracking Poll on Health Information and Trust: Use of AI For Health Information and Advice
This poll finds that about as many adults are turning to AI for health information as social media, with health care costs and access driving many users, particularly younger users.
Flavio Bolsonaro Inches Ahead of Lula in Brazil Election Poll
Flavio Bolsonaro edged ahead of President Luiz Inacio Lula da Silva in the run-up to October’s election, with a new poll showing for the first time that the right-wing senator is leading the race.
How magnetic is the moon? A new study cracks the long-standing mystery
Researchers believe rock samples taken from the Apollo missions gave scientists a misleading impression
Entertainment Poll: Who is the highest paid (annually), active athlete on the planet?
Test your knowledge!
Scientists just discovered bees and hummingbirds are drinking alcohol
Flower nectar often contains small amounts of alcohol, meaning pollinators like hummingbirds are drinking it all day long. Despite consuming human-equivalent amounts, they show no signs of intoxication—suggesting a surprising evolutionary tolerance.
GOP candidates lead in CADEM-commissioned gubernatorial poll
This extraordinary pressure campaign is only just beginning
Trump sinks to record low approval rating due to Iran war in new poll
President Donald Trump's approval rating dropped to 36%, its lowest level since his return to the White House, according to a new Reuters/Ipsos poll.
Steve Kornacki's guide to the next big elections on the calendar: From the Politics Desk
Plus, where talks to end the DHS shutdown stand.
Defiant Democratic candidates in California governors race dig in
State Democratic Party leaders, including Gov. Gavin Newsom, appear unwilling to force lower-polling Democrats out of the race.
How easing regulations on heavy metals air pollution could impact health | Harvard T.H. Chan School of Public Health
A recent repeal of federal environmental regulations aimed at limiting the emission of mercury and other heavy metals from power plants could have serious health impacts, according to Harvard Chan School experts.
Danish Social Democrat Premier Takes Lead in Parliamentary Vote
Danish Prime Minister Mette Frederiksen’s party is on track to win the most seats in an election shaped by Donald Trump’s threats over Greenland, according to exit polls.
New poll finds Trump's net favorability at record low in Wisconsin
The first Marquette University Law School poll conducted after the U.S. attacks on Iran found 61% oppose the war, with divides among Republicans.
Scientists Must Speak Clearly, Especially in Court: Five Tips for Clear Communication
As climate impacts intensify, so does the legal push to hold polluters accountable, protect vulnerable communities, and enforce environmental laws. And in these legal cases, science is key. Because science can’t present itself on the stand, scientists are essential to give scientific results a voice
Got a burning sports question? Ask The Athletic’s daily newsletter
Send The Pulse your most pressing sports questions, and we'll regularly share answers from our experts.
Cypress business owner charged with felony water pollution, authorities say
Detectives said the Cypress company, which power washes dump-truck engines, was dumping contaminated wastewater into a drainage ditch that eventually leads all the way to the Gulf.
Ron DeSantis, Nikki Haley tie for 3rd in New Hampshire GOP 2028 poll, far behind Marco Rubio, JD Vance
New polling shows another run for the Governor may be challenging.
The Core Entertainment Hires Sarah Pfeiffer As Head Of Marketing & Gabriella Pulley As Chief Of Staff
The Core Entertainment is continuing to scale its company, with the recent news of two new hires added to the leadership team. Sarah Pfeiffer has been named
Exit polls suggest Italy's Meloni has narrowly lost justice referendum vote
Exit polls on Monday suggested Italian Prime Minister Giorgia Meloni had narrowly lost a referendum on her flagship reform of the judicial system, dealing a potential blow to the ruling coalition ahead of next year's general election.
WSU launches bilingual video series to help beekeepers improve colony health
Researchers with WSU's Honey Bee and Pollinators Program have produced a new video series giving novice keepers a strong introduction to best practices and the science of apiculture, in both Spanish and English.
As President Trump’s Attacks on Science Escalate, Big Oil Moves to Avoid Legal Accountability
This piece was originally published in Climate Home News. The Supreme Court of the United States (SCOTUS) recently agreed to hear arguments in Boulder v. Exxon and Suncor a case that could decide whether communities harmed by climate change can hold polluters accountable in state court. Origin
Small swings, high drama: why UK polls are less volatile than they seem
In what is beginning to look like a fragmented five-party system, small swings carry outsized political consequences
These Michigan U.S. Senate candidates took money from ICE contractors
Anti-ICE messaging is expected to be featured prominently in Michigan's hotly contested U.S. Senate Democratic primary.
Scientists Open Moon Rocks Locked Away Since 1972 – and Find Something Totally Unexpected
Decades after being sealed away, Apollo-era lunar samples are revealing unexpected chemical signatures that challenge long-standing assumptions about the Moon’s composition.
Exit polls suggest lead for Merz's SPD in key west German state
Far-right Alternative for Germany party (AfD) looks set for a record score in western Germany
Slovenia liberals take narrow election lead over conservatives: exit poll
Exits polls suggest Prime Minister Robert Golob has blocked a fourth term for right-winger Janez Janša
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Slovenians head to polls in tight race marked by spy scandal
Allegations of espionage and foreign interference have cast a shadow over the parliamentary election
MAGA says the SAVE America Act is crucial. A new poll shows Americans don’t agree
To hear some prominent MAGA voices tell it, the marathon Senate debate over the “SAVE America Act” is an existential one for the Republican Party. But the urgency to pass the legislation is not felt by Americans more widely.
'Not a done deal': Democrats start to sweat over Virginia's redistricting referendum
The unique nature of the April special election and the state's recent redistricting history have presented challenges for Democrats, even as they hold a financial edge in the race.
Another Planet Entertainment Producing Free Show Celebrating 30 Years of OM Records
Longtime dance label OM Records is celebrating its 30th anniversary with a free concert produced by Another Planet Entertainment.
Many Americans plan to cut food to afford ACA health insurance, new poll shows
About 8 in 10 Americans who re-enrolled in Affordable Care Act marketplace coverage say their health care costs are higher this year, according to a new survey from the health care research nonprofit KFF.
Most ACA enrollees cutting back on food, household needs to pay for health care: Poll
A little more than half of Affordable Care Act (ACA) Marketplace enrollees reported cutting back on spending for food, clothing and other basic household items to afford health care that’s be…
What Americans are giving up to afford ACA health insurance, according to a new poll
A new KFF survey shows many Americans who had Affordable Care Act marketplace health insurance last year are struggling with high health costs. The findings come three months after the expiration of enhanced tax credits that had offset most enrollees' monthly premiums.
9% of ACA enrollees go uninsured after enhanced subsidies expire, poll finds
Many Americans face financial pressures after Affordable Care Act enhanced premium subsidies expired at the end of 2025.
Poll shows Americans are cutting back on basics to afford health care
A new KFF survey shows many Americans who had Affordable Care Act marketplace health insurance last year are struggling with high health costs.
California’s proposed billionaire tax gains majority support in new poll, with a partisan split on voter ID
A new poll shows California voters are sharply divided over two brewing ballot measures: a one-time tax on billionaires and new rules and procedures to verify voter citizenship.
Chris Weidner: Climbing past the politics: the Iran I remember
Our first impression of Tehran was overwhelming. From the hillside beneath the Alborz Mountains we looked upon a sea of mostly white buildings — a metropolis home to more than 8 million people. Down there, thick pollution stung my eyes and …
GOP candidate cites ‘failure’ of Newsom, Dems as new poll shows Republicans leading crowded California field
Steve Hilton, a Republican running for governor, said that the “absolute failure" by California Gov. Gavin Newsom and Democrats means that the GOP has a real shot at victory this year.
Texas primary results showed limitations of polling
Many factors explain why pollsters face challenges in getting good sample sizes that truly reflect who is going to cast a ballot.
As polls head toward closing time, precincts report low turnout
A roundup of the results in key Chicago-area congressional primaries.
Kiki Shepard dead: Longtime 'Showtime at the Apollo' co-host was 74
Kiki Shepard, best known for co-hosting the variety show 'Showtime at the Apollo,' has died, her representative confirmed. The Harlem theater remembered Shepard as a 'true Apollo legend.'
Poll: Mass. Legislature underwater in court of public opinion
Massachusetts residents highly prize transparency and want to see an audit of the Legislature, the poll found.
Syracuse.com’s 2026 media day baseball coach poll: Most likely to have breakout season? (photos)
Some key players could be on the verge of making a name for themselves this season.
US troops in Iran? What Americans think, and what it would mean
Polling suggests the idea of US troops on the ground in Iran is a complete nonstarter for Americans overall — and even a tough sell for the GOP base.
2026 NAMI-Ipsos Workplace Mental Health Poll
A NAMI-Ipsos poll conducted in January – February 2026 highlights what mental health support American employees are looking for from their companies. This data reflects employee sentiment across industries at companies with at least 100 employees.
Partisanship and science
I recently participated in a symposium of the Denver-based Institute for Science & Policy, during which I had a “fireside chat” with Tony Mills of the American Enterprise Institute. Mills has written extensively on the politicization of science, and the two of us had a very enjoyable hour-long conversation on the topic. You can watch it below. The main questions we dealt with are why there is such a vast partisan gap in trust of science, and to what extent this is a unique moment. Mills helpfully brings a good deal of data to the discussion, as he did in this useful piece at Issues in Science & Technology. Tusk depends on reader support. To support this work, please become a paid subscriber. Subscribe Note this graph, drawing on a range of survey data to demonstrate partisan attitudes toward science since 1970s. As it demonstrates, there’s been a very sharp partisan divergence in confidence in science during the Trump Era, starting prior to the Covid pandemic. At least in part, we can attribute this to a rise in populist anti-science rhetoric embraced by Trump, his appointees, and those in his media orbit. But as the graph also shows, the partisan divide has existed in the past, and it’s not always in the same direction. The largest divergence in party views toward science prior to 2016 was in the 1970s, when liberals equated scientific achievement with the military-industrial complex and thus trusted it less. That era of scientific mistrust is often overlooked. Indeed, as Mills notes, the Moon landings (1969-72), which today are considered one of the last great moments of national unity, were experienced nothing like that at the time. There was sharp debate back then over whether the Apollo missions were worth the vast expenditures when the country had so much else to deal with. It’s outside the dataset, and we don’t have the partisanship lens for it, but the 1950s was another deeply anti-science decade, with critics of intellectuals and college professors alleging their ties to communism and their lack of commitment to basic American moral beliefs. This was the subject of Richard Hofstadter’s 1962 book Anti-Intellectualism in American Life, in which he quotes religious leaders like Franklin Graham: [In place of the Bible] we substituted reason, rationalism, mind culture, science worship, the working power of government, Freudianism, naturalism, humanism, behaviorism, positivism, materialism, and idealism. [This is the work of] so-called intellectuals. Thousands of these “intellectuals” have publicly stated that morality is relative—that there is no norm or absolute standard.… This fervor was heavily whipped up by Sen. Joe McCarthy (R-Wisconsin), although it’s clear that not all his fellow Republicans were on board with his red-baiting. What ended that era? The simple answer is the 1957 launch of Sputnik. Americans became afraid that they were losing to Soviet scientists, and suddenly university researchers and government projects were awash with funding. In our conversation, I asked Mills about the possibility of us having a Sputnik moment again that would rally the American public in favor of science today. Mills argued that the COVID-19 pandemic was essentially a Sputnik moment — a terrifying threat to all Americans that required scientific advances to address. But thanks in part to political polarization and the populist and conspiratorial leanings of Donald Trump, we got the opposite of a unifying moment. Many Americans turned against science, despite science actually stepping up in that moment. As we discussed in the chat, it’s not clear what scientists could or should be doing in this moment to increase faith in their work. As Mills notes, one of the chief complaints against scientists and professors is that they’ve become too political; scholars becoming even more political might not help them achieve their goals. This (mainly Republican-driven) anti-science era will end, of course, but it’s not clear what event will bring that about. Share
As Florida leads on free-market policies, new poll shows voters want federal regulators to follow suit
A bipartisan majority supports President Donald Trump's push to end politically driven banking.
Villaraigosa's dreams for a political comeback meet reality
Villaraigosa hasn't held office since 2013. That's a problem for the former mayor, who is at the bottom of the polls.
Poll: Israel's standing plummets among Democrats, fueling primaries on the left
More registered voters view Israel negatively than positively in the latest NBC News poll, driven by change among independents and especially Democrats.
Driving habits of teens and young adults
Nearly all parents think their teen or young adult child’s driving ability is as good or better than other teens and young adults. 1 in 3 parents worry their teen or young adult driver will cause an accident. 1 in 4 parents have taken steps to address their teen or young adult child’s driving behavior. Witnessing risky driving behavior does not affect parents’ rating of their teen or young adult child’s driving ability.
People turn to private health care to beat long NHS waits, says watchdog
The patient watchdog warns of two-tier service as polling shows numbers paying for care is on the rise.
See Kansas basketball’s ranking in USA TODAY Sports Coaches Poll
Kansas basketball is about to set out on a NCAA tournament run. Here’s where the Jayhawks rank in the top 25 of the USA TODAY Sports Coaches Poll.
DeGette challenger Melat Kiros trounces 15-term Democratic incumbent in Denver delegate vote
The 28-year-old, first-time candidate challenging Democratic U.S. Rep. Diana DeGette in this year’s primary soundly defeated the 15-term incumbent in a delegate preference poll conducted Saturday at a county party assembly in Denver. Melat Kiros, the daughter of Ethiopian immigrants and a former corporate attorney, received nearly twice as many votes as DeGette in a […]
France: Far-right strength put to test in local elections
Voters in France are heading to the polls in local elections seen as a litmus test for next year's presidential vote. A main focus will be the mayoral contest in Paris.
Opinion | The Political Cost of Trump’s War
The Republican pollster Kristen Soltis Anderson joins E.J. Dionne Jr. and Robert Siegel to discuss Trump’s falling approval rating and what it portends for November.
Polly Baca elected to DNC
Forty-Five Years Ago This Week: After her loss to Republican U.S. Rep. Hank Brown the previous year in the race for the 4th Congressional District, state. Sen Polly Baca-Barragan, D-Thortnon, was elected as one of the three vice-chairs of the Democratic National Committee. “It was exciting but a lot of hard work,” Baca-Barragan said. “I […]
Video: Opinion | The Political Cost of Trump’s War
The Republican pollster Kristen Soltis Anderson joins E.J. Dionne Jr. and Robert Siegel to discuss Trump’s falling approval rating and what it portends for November.
Contributor: Federal power grabs on elections are not about fraud
Trump has called the SAVE Act his top priority. But why? His commission found no widespread problem that needed solving.
3 Democrats compete for most favorable governor's candidate in poll
The governor's race remains crowded, and polling has been anything but consistent.
Oscars walks political tightrope as poll shows Californians wary of Hollywood’s influence
Even in California, just 29 percent of voters say Hollywood has a positive impact on American culture, according to a new poll by POLITICO and its partners.
Trump administration live updates: Poll finds widespread distrust of economic and political systems
Get live updates and the latest news as an NBC News poll finds widespread political and economic distrust, the U.S. launches tariff probes, and Trump seeks passage of the SAVE America Act.
One-third of Americans skip meals or other needs to afford health care
About half of middle-income households said they have delayed a major life event because of medical costs, new Gallup polls found.
Poll: Voters who say economic and political systems are stacked against them tie a record high
Democratic pollster Jeff Horwitt said the numbers indicate “historic levels of anger and disgust with our political and economic systems.”
Bookman: Has the Kemp model fallen out of fashion in Georgia politics?
Brian Kemp, in his eighth and final year as governor, still enjoys significant popularity. In an Emerson poll conducted last weekend, only 24.5% of Georgians said they disapprove of his job performance, which in this divisive era is remarkable. You might think that kind of long-running success would make Kemp a model to be emulated […]
One-Third of Americans Cut Back to Cover Healthcare Expenses
According to new West Health-Gallup research, millions of Americans report cutting back on expenses and delaying plans because of healthcare costs.
Americans are increasingly worried about voting, new poll shows
Americans’ confidence that their elections will be run fairly has dropped to its lowest point in years, according to a new PBS News/NPR/Marist poll.
Pleasant Valley 6th Graders Lead the Way in Supporting Science Camp
EL DORADO COUNTY, Calif. – Pleasant Valley Middle School (PVM) students Emmy Emmons and Hazel Gillihan recently became the first students to present at the Gold Oak Union School District (GOUSD) February Board Meeting, sharing their experiences at Science Camp at Sly Park Environmental Education Center in Pollock Pines this past September. Working as a […]
California Democrats hope new polling will nudge candidates to exit
The California Democratic Party chair said Tuesday that the party is spending “multiple six figures” to conduct and post six surveys of the race.
What to watch for in the Georgia special election: From the Politics Desk
Plus, new polling shows voters are wary of AI.
How pollutants interact inside the body to impact health | Harvard T.H. Chan School of Public Health
Peng Gao studies the “exposome”—the measure of an individual’s total environmental exposures over the course of their life and how those exposures impact biology and health.
Polls show what Americans think about the war in Iran
Americans are divided along party lines on U.S. military action against Iran, according to polls conducted since the war began.
UConn no longer unanimous No. 1 in women’s basketball coaches poll
In the latest USA TODAY Sports’ women’s basketball coaches poll, one coach on the panel believes that UCLA is the best team in the country.
‘Black rain’ in Iran prompts WHO health warning
The World Health Organization (WHO) on Tuesday warned that strikes on Iranian oil depots causing “black rain” could lead to respiratory problems as toxic pollutants disperse through the…
Where American support for Trump’s Iran strike stands as new polls roll in
Most but not all of the latest national polls indicate majority opposition to the U.S. military strikes President Donald Trump ordered against Iran in Operation Epic Fury.
CMOC Congo Mine Pollution Damaged Local Health, Report Says
Air pollution by the world’s biggest cobalt producer appears to have damaged the health of local communities in the Democratic Republic of Congo, according to an investigation by environmental groups.
Unlike in Past Conflicts, Most Americans Oppose Iran Attacks
While the public has historically backed military intervention initially in international conflicts, deep polarization has left the latest strikes against Iran with record-low support.
Poll: Majority of voters say risks of AI outweigh the benefits
In new NBC News polling, the only topics that were less popular than AI were the Democratic Party and Iran.
Jean-Michel Aulas ruffles feathers in Lyon after swapping football for politics
Club’s former owner leads the polls in spiky mayoral race but is accused of putting forward ‘nothing of substance’
Georgia voters choosing a successor to Marjorie Taylor Greene in US House
Georgia voters are heading to the polls to choose a successor in Congress to Marjorie Taylor Greene
Poll: Most Americans oppose war in Iran, but most Republicans support it
A majority of Americans oppose the United States' military action in Iran, according to a new NPR/PBS News/Marist poll. However, that opposition breaks down along party lines, with a majority of Republicans saying they support the war. We discuss whether the lack of public support could alter President Trump's next steps and how the war could affect this year's midterm elections.This episode: voting correspondent Miles Parks, senior White House correspondent Tamara Keith, and senior political editor and correspondent Domenico Montanaro.This podcast was produced by Casey Morell and Bria Suggs, and edited by Rachel Baye. Our executive producer is Muthoni Muturi.Listen to every episode of the NPR Politics Podcast sponsor-free, unlock access to bonus episodes with more from the NPR Politics team, and support public media when you sign up for The NPR Politics Podcast+ at plus.npr.org/politics.
Where Kansas basketball ranks in USA TODAY Sports Coaches Poll update
Kansas basketball is preparing for the Big 12 Conference tournament this week. Where does it rank in the latest USA TODAY Sports Coaches Poll update?
College basketball rankings: Duke leads USA TODAY Sports Top 25 poll entering March Madness
With the power conferences headed toward their respective tournaments, Duke remains No. 1 in a shuffled USA TODAY Sports men's basketball poll.
Pre-midterms, GOP confronts cooling support from young men over Trump
Polling suggests a softening of support among young men over Trump's policies, threatening Republicans' hopes of retaining majorities in Congress.
Democrats sink to new voter low, Republicans also underwater: poll
NBC News poll shows Democratic Party approval at just 30%, with only 62% of Democrats viewing their own party positively—signaling major challenges.
'It's a very unique biological specimen': The scientists using menstrual blood to diagnose diseases
From diagnosing endometriosis and cervical cancer to diabetes, vitamin D deficiency, and pollution exposure, here's what menstrual blood can reveal about your health.
After UnitedHealth moved in, Oregon sought to rein in corporate health care. Now, it’s facing an early test
PeaceHealth's move to replace ER doctors with ApolloMD clinicians is testing a new state law limiting corporate medicine.