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Prop 40 is dividing CA labor unions and experts argue the fight goes well beyond a billionaire tax

SEIU-United Healthcare Workers West is spearheading Proposition 40, arguing the tax is necessary to offset major federal health care cuts. But the opposition includes groups that have often found themselves politically aligned with organized labor, including the California Teachers Association, California Professional Firefighters and the State Building and Construction Trades Council of California.

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Sep 9 • 7:39 PM EDT • Politics • abc7news.com
Is Accenture's Business Falling As Fast As Its Stock?

Accenture (ACN) trades at $179.03, about 53% below its two-year high, the price of a business the market thinks is ending. Over the last twelve months, it generated $12.58 billion of free cash flow, a yield of 11.5% on its market value against a 4.4% median for the S&P 500. Both facts are true. The argument between them is about growth.

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Sep 9 • 7:19 PM EDT • Business • finance.yahoo.com
Is Accenture’s Business Falling As Fast As Its Stock?

Accenture (ACN) trades at $179.03, about 53% below its two-year high, the price of a business the market thinks is ending. Over the last twelve months, it generated $12.58 billion of free cash flow, a yield of 11.5% on its market value against a 4.4% median for the S&P 500. Both facts are true.

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Sep 9 • 7:18 PM EDT • Business • trefis.com
New wave of healthcare fraud enforcement

In past years, federal and state authorities typically initiated healthcare fraud investigations based on whistleblower complaints and audits. While that still occurs, the model is changing. Federal enforcement agencies are increasingly using sophisticated data analytics, artificial intelligence, and coordinated investigative efforts to identify potential fraud. The Department of Justice (DOJ),…

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Sep 9 • 6:48 PM EDT • Health • mcafeetaft.com
Buffalo's Wednesday injury report

Bills RB Ty Johnson and S Jordan Hancock miss practice

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Sep 9 • 6:23 PM EDT • Sports • sports.yahoo.com
Billy Joel addresses his health, tells fans not to worry: 'I'm still here'

Billy Joel shared an update about his health more than a year after being diagnosed with normal pressure hydrocephalus.

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Sep 9 • 5:56 PM EDT • Health • abcnews.com
Patriots Have Former Buffalo Bills Weapon to Protect Drake Maye

The New England Patriots made obvious investments around Drake Maye, but a quieter addition could become especially useful when defenses turn up the pressure. Reggie Gilliam arrived in New England after six seasons with the Buffalo Bills, giving offensive coordinator Josh McDaniels a true fullback with a track record as one of the NFL’s better […] The post Patriots Have Former Buffalo Bills Weapon to Protect Drake Maye appeared first on HEAVY.

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Sep 9 • 5:47 PM EDT • Sports • sports.yahoo.com
Bill Barnwell Picks Lions to Go Worst to First

Bill Barnwell picks the Lions to win the NFC North and the Vikings to miss the playoffs. #Lions

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Sep 9 • 5:30 PM EDT • Sports • sports.yahoo.com
NM US Sen. Heinrich tours Albuquerque Food Farmacy to tout fruits and vegetables as medicine

A bill Heinrich co-sponsored aims to study whether Medicare and Medicaid paying for food aid to patients staves off chronic disease.

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Sep 9 • 5:07 PM EDT • Health • sourcenm.com
Hollywood’s ‘new business model’ comes into view as Gen Z shows a moviegoing taste that combines ‘fast food and fine dining’

Theaters sold nearly 249 million fewer tickets than in 2019 but still set a $4.7 billion summer record. It’s not 2019 anymore.

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Sep 9 • 4:56 PM EDT • Business • fortune.com
Buffalo Bills 2026 Game-by-Game Prediction

Predicting each game on the Buffalo Bills' 2026 NFL schedule.

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Sep 9 • 4:56 PM EDT • Sports • sports.yahoo.com
Enbridge nears $2 billion deal for Blackstone's Pony Express crude pipeline, Bloomberg News reports

Enbridge is in advanced ‌talks to buy the major crude oil ​pipeline Pony Express ​Pipeline in the U.S. from Blackstone-owned ⁠Tallgrass Energy for ​about $2 billion, Bloomberg News ​reported on Wednesday, citing people familiar with the matter.

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Sep 9 • 3:49 PM EDT • Business • reuters.com
ICE’s ‘Midway Blitz’ operation cost Chicago businesses $1.2 billion: Study

Immigration and Customs Enforcement’s (ICE) Chicago-area operation cost local businesses more than $1.2 billion last year, according to a new study. The study, conducted by researchers at the Unive…

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Sep 9 • 3:33 PM EDT • Business • thehill.com
Trump administration fires prosecutor in dropped case against politically-linked Indian billionaire

Gautam Adani had faced a criminal case that Trump administration moved to drop.

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Sep 9 • 3:29 PM EDT • Politics • nbcnews.com
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‘Blessing’ Tennesseans with Better Oral Health

Back in 2012, Union City businessman William “Bill” Latimer had an idea that has helped thousands of Tennesseans smile.

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Sep 9 • 2:37 PM EDT • Health • news.uthsc.edu
University of Iowa Health Care nixes plans for new $2B tower

University of Iowa Health Care has scrapped plans to build a new $2 billion inpatient tower — at least for now — and rather is “modernizing and expanding existing spaces across the health system, specifically on the university and downtown campuses.”

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Sep 9 • 2:32 PM EDT • Health • thegazette.com
Sports betting is everywhere now—here are the rules bettors might not realize they're breaking

Sports podcaster Bill Simmons recently had wagers voided after breaking a sportsbook rule he said he didn't know about.

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Sep 9 • 2:30 PM EDT • Sports • cnbc.com
ERNEST Opens Up About Mental Health After Leaving Ella Langley Tour

ERNEST is opening up about his mental health after leaving Ella Langley's tour.

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Sep 9 • 2:29 PM EDT • Health • billboard.com
Youth sports become big business, putting stress on families

American youth sports have become a 40 billion dollar business. But youth travel sports also come with increasing costs and challenges and parents are bearing the costs..

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Sep 9 • 2:26 PM EDT • Business • news.azpm.org
Youth sports become big business, putting stress on families

American youth sports have become a 40 billion dollar business. But youth travel sports also come with increasing costs and challenges and parents are bearing the costs..

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Sep 9 • 2:26 PM EDT • Sports • news.azpm.org
Republicans gather in Dallas for two-day midterm convention billed as 'Trump-a-Palooza'

The highly unusual midterm convention puts President Donald Trump at the center of this fall’s midterm elections — whether the candidates running like it or not.

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Sep 9 • 2:07 PM EDT • Politics • pbs.org
Two Tiny Lifeforms Built a Bridge Too Small to See—and May Have Made Humanity Possible

Stromatolites, formed by microbial mats, hold evidence of a symbiotic relationship that possibly kickstarted complex life billions of years ago.

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Sep 9 • 2:00 PM EDT • Science • popularmechanics.com
Americans prefer getting bitten by a mosquito or stubbing their toe than today’s politics

Respondents still prefer today’s politics over billionaires, telemarketers, health insurance companies, artificial intelligence, Elon Musk and root canals.

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Sep 9 • 1:29 PM EDT • Politics • 13abc.com
Major investor of Norwalk-based Xerox urges review of financial services business

Xerox shareholder STARTEEPO is urging Norwalk-based Xerox to review a sale of Xerox Financial Services, which it values at up to $1.5 billion.

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Sep 9 • 12:34 PM EDT • Business • hartfordbusiness.com
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ICYMI—Hagerty Joins Varney & Co. on Fox Business to Discuss Tariffs on Israel, Affordability

WASHINGTON—Today, United States Senator Bill Hagerty, (R-TN), a member of the Senate Foreign Relations, Appropriations, and Banking Committees, joined Varney & Co. on Fox Business to discuss the foreign trade restrictions on Israel and affordability ahead of the midterm election. *Click the photo above or here to watch* Partial Transcript Hagerty on foreign trade restrictions on Israel: I’m disappointed, […]

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Sep 9 • 12:16 PM EDT • Business • hagerty.senate.gov
Google DeepMind’s AlphaGenome Takes Aim at One of Genetics’ Biggest Problems

Google DeepMind has released a huge new dataset that could make it easier for scientists to study how changes in our DNA affect the way the body works. Called AlphaGenome Atlas, it contains predictions for more than 9 billion possible single-letter changes in the human genome. The dataset is about one petabyte in size and […]

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Sep 9 • 12:03 PM EDT • Science • hpcwire.com
Buffalo Museum of Science Unveils $3 Million Science Stadium Permanent Exhibit in Partnership with the Bills, Sabres, and Bandits

Transformative, interactive exhibit merges Western New York’s deep passion for sports with STEM learning; Ribbon-cutting ceremony set for September 24 before September 26 public opening.

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Sep 9 • 9:59 AM EDT • Science • buffalobills.com
Buffalo Museum of Science Unveils $3 Million Science Stadium Permanent Exhibit in Partnership with the Bills, Sabres, and Bandits

Transformative, interactive exhibit merges Western New York’s deep passion for sports with STEM learning; Ribbon-cutting ceremony set for September 24 before September 26 public opening.

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Sep 9 • 9:59 AM EDT • Sports • buffalobills.com
Buffalo Museum of Science unveils $3 million Science Stadium permanent exhibit in partnership with the Bills, Sabres, and Bandits

Transformative, interactive exhibit merges Western New York’s deep passion for sports with STEM learning; Ribbon-cutting ceremony set for Sept. 24 before Sept. 26 public opening.

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Sep 9 • 9:59 AM EDT • Science • nhl.com
Buffalo Museum of Science unveils $3 million Science Stadium permanent exhibit in partnership with the Bills, Sabres, and Bandits

Transformative, interactive exhibit merges Western New York’s deep passion for sports with STEM learning; Ribbon-cutting ceremony set for Sept. 24 before Sept. 26 public opening.

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Sep 9 • 9:59 AM EDT • Sports • nhl.com
Luma locks down 15-year, $410M fund for life science investments

Luma Group today announced the final close of its inaugural life sciences venture capital fund, totaling $410 million. The New York-based investment firm has had a grip on life sciences since its founding in 2023. The funds unveiled today, dubbed LumaBio Fund I, include investments that have already been made into more than 10 biotechs. They include the likes of eye disease-focused Character Biosciences, rebranded Belgian biotech Coultreon Biopharma and cellular rejuvenation company Altos Labs. The fund saw early success when one of the companies it co-founded, called Vaccine Company, was picked up by Eli Lilly earlier this year for up to $1.55 billion. The acquisition of the in vivo nanoparticle technology-focused biotech formed part of a trio of vaccine buys for the Big Pharma, which has itself been on a prolonged spending spree in 2026. Luma's fund is structured as a 15-year investment with plans to support groundbreaking science and support companies through key milestones from discovery to commercialization, Luma explained in the release. "We founded Luma Group on the belief that extraordinary science, supported by patient, long-term capital, has the power to improve millions of lives," Joshua Fink, founder and managing member of Luma Group, said in the release. "This fund represents more than capital—it is a commitment to partnering with extraordinary innovators as they translate visionary science into life-changing medicines."

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Sep 9 • 9:43 AM EDT • Science • fiercebiotech.com
Bills Mafia, who are we rooting for in Week 1?

Rooting Interests before we know what our rooting interests are

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Sep 9 • 9:00 AM EDT • Sports • sports.yahoo.com
Andy Burnham: National security can't come at expense of social security

The prime minister says he will fund defence and get the welfare bill down in "the Labour way".

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Sep 9 • 8:30 AM EDT • Politics • bbc.com
Complete Your Evolution With “Perfect Eclosion – Perfectly Ultimate Great Moth”! [YA01]

The Perfectly Ultimate Great Moth takes flight!

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Sep 9 • 8:18 AM EDT • Technology • ygorganization.com
Capitol agenda: Will Schumer go long for college sports? - Live Updates

Schumer must decide if he wants to steer his members toward helping Republicans reach the 60-vote threshold on what could be the sweepiest bill the chamber passes before the midterms.

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Sep 9 • 8:00 AM EDT • Sports • politico.com
Guelph meat science faculty went from five to zero

Federal funding flowed to Protein Industries Canada and plant proteins after 2018 while a $32-billion meat industry went without its share.

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Sep 9 • 6:15 AM EDT • Science • farmtario.com
CNBC's Official NFL Team Valuations 2026: Here's how the 32 franchises stack up

The average National Football League team is now worth $10.36 billion, up 35% from a year ago.

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Sep 9 • 6:00 AM EDT • Sports • cnbc.com
The Market Forces Quietly Adding Thousands To Patient Bills

By Elisabeth Rosenthal and KFF Health News HealthDay ReportersWEDNESDAY, Sept. 9, 2026 (HealthDay News) — After a failed round of in vitro fertilization this year, Anne Hug’s fertility doctor said she had a single polyp in her uterus that should be removed to improve the chance of pregnancy. Hug, a ...

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Sep 9 • 5:45 AM EDT • Health • usnews.com
How A.I. Tokens Work

As large language models become more advanced, they use ever more resources. Who will foot the bill?

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Sep 9 • 5:06 AM EDT • Technology • nytimes.com
Republicans kick off a 'Trumpapalooza' of a midterm convention Wednesday in Texas

Republicans have never held a midterm convention before. But there's also never been a president like Donald Trump. Billed as a "Trumpapalooza," the unprecedented event kicks of in Dallas Wednesday.

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Sep 9 • 5:00 AM EDT • Politics • npr.org
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Entertainment Agency Rep, Journalists in 3 Billion Won Stock Probe

Entertainment Agency Rep, Journalists in 3 Billion Won Stock Probe Authorities probe front-running scheme, 300 stocks, 3 billion won illicit gains

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Sep 9 • 3:20 AM EDT • Entertainment • chosun.com
Prediction: Netflix's Advertising Business Passes $6 Billion in 2027

Netflix collects about a dollar a month in ad revenue per viewer. Is that low enough to power another doubling?

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Sep 9 • 2:01 AM EDT • Business • finance.yahoo.com
How Meta’s Billions for Teen Mental Health Can Make a Real Difference

Instead of repeating the mistakes they made with tobacco money, states should set clear goals — and measure outcomes through dashboards accessible to all — for programs addressing social media’s harms to teenagers.

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Sep 9 • 12:49 AM EDT • Health • governing.com
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August 2026 Michigan legislative roundup: Money out of politics, prison safety and primary care

Each month, The Michigan Daily publishes a compilation of some of the most relevant bills in the Michigan Legislature for students.

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Sep 9 • 12:03 AM EDT • Politics • michigandaily.com
Allegheny County Council proposes bill that could regulate AI use in political campaign materials

Members of Allegheny County Council on Tuesday introduced a bill that would require political candidates to disclose their use of artificial intelligence in campaign materials, an effort aimed at preventing voters from being misled by AI-generative content. If passed, the ordinance would establish disclosure requirements for AI-generated campaign content used

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Sep 8 • 11:07 PM EDT • Politics • triblive.com
Macau wants to be a ‘business city,’ not just a gaming hub—and it’s spending $16 billion to help it get there

IPIM board president Alex Che Weng Keong says the casino hub can use its regulatory autonomy and Portuguese heritage to become a "tech city."

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Sep 8 • 10:49 PM EDT • Business • fortune.com
See rally for CA bills targeting corporate profits for immigrant detention
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Sep 8 • 9:23 PM EDT • Politics • sacbee.com
What Will Life Science Orgs Do When The AI Bill Comes Through?

AI is transforming clinical development, but what happens when usage costs spike? Jon Newton explains how to govern it before the bill lands.

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Sep 8 • 8:00 PM EDT • Science • clinicalleader.com
Cleveland County judge denies preliminary injunction in Norman Entertainment District lawsuit

On Tuesday, a Cleveland County Judge issued a preliminary injunction, pausing construction on Norman’s $1 billion Rock Creek Entertainment District.

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Sep 8 • 7:49 PM EDT • Entertainment • kfor.com
Canada just hit U.S. goods with new tariffs. Here's what it could mean for NY

Canada is hitting about $20 billion in U.S. goods with new tariffs. Here's what an economist says it could mean for New York.

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Sep 8 • 6:49 PM EDT • Politics • spectrumlocalnews.com
Bills Announce Exciting Josh Allen News Before Season Opener

The Buffalo Bills announced that quarterback Josh Allen is among the six players picked as captains for the 2026 season. The post Bills Announce Exciting Josh Allen News Before Season Opener appeared first on HEAVY.

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Sep 8 • 6:38 PM EDT • Sports • sports.yahoo.com
$30 million maintenance bill looms over Roanoke’s aging entertainment venue

A laundry list of decay, broken equipment, and failing infrastructure inside the aging building has left the city facing an estimated maintenance and repair bill of at least $30 million

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Sep 8 • 6:36 PM EDT • Entertainment • wdbj7.com
Billy Joel mourns friend and former drummer Jon Small

NEW YORK — Billy Joel mourned the death of his friend and former bandmate, drummer Jon Small, on Monday. He was in his late 70s. “RIP Jon Small,” Joel posted

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Sep 8 • 5:59 PM EDT • Entertainment • recorderonline.com
Blackstone explores sale of ZO Skin Health, sources say

Investment firm Blackstone is looking to sell ​medical-grade skincare company ZO Skin ‌Health, which could be valued at around $2 billion in any deal, according to ​people familiar with the matter.

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Sep 8 • 5:19 PM EDT • Health • reuters.com
New York Business Thought It Was Paying Its Bills Until $161K Went Somewhere Else

A New York employee thought they were doing exactly what they were supposed to do when an email instructed them to start sending business payments to a new bank account. Three transfers and more than ...

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Sep 8 • 5:17 PM EDT • Business • yahoo.com
The bill for Trump’s Medicaid cuts is coming due

Though much attention has centered on the closure of rural hospitals, quieter transformations could reshape healthcare for all patients.

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Sep 8 • 4:39 PM EDT • Health • ms.now
Sony Music Japan President Atsuhiro Iwakami: Interview

Sony Music Japan President Atsuhiro Iwakami shares his thoughts on what it will take for Japanese content to score hits abroad.

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Sep 8 • 3:58 PM EDT • Entertainment • billboard.com
US House bill requires criminal background checks on Hollywood sets

A House bill would require criminal background checks for Hollywood set workers who supervise or regularly interact with minors.

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Sep 8 • 3:47 PM EDT • Entertainment • thetelegraph.com
Buffalo Bills name 6 captains for 2026 NFL season

Who joins quarterback Josh Allen and linebacker Terrell Bernard as an official captain for the Buffalo Bills in 2026?

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Sep 8 • 3:28 PM EDT • Sports • sports.yahoo.com
Father-Son Duo Launch A Talent Discovery And Entertainment Ecosystem For Independent Performers

Father-son duo launch a talent discovery and entertainment ecosystem for independent artists because likes alone don't pay the bills.

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Sep 8 • 3:09 PM EDT • Entertainment • afrotech.com
Northrop Grumman lands defense contracts worth $1.37B

Falls Church-based defense supplier Northrop Grumman landed two major military contracts collectively worth $1.37 billion.

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Sep 8 • 3:05 PM EDT • Business • virginiabusiness.com
As Latino shoppers hunkered down, Cook County businesses lost $1.26 billion

Federal immigration enforcement cost Cook County businesses an estimated $1.26 billion in lost sales last year as Latino residents sharply curtailed trips outside their neighborhoods to shop and dine.

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Sep 8 • 2:32 PM EDT • Business • chicagobusiness.com
As Latino shoppers hunkered down, Cook County businesses lost $1.26 billion

Federal immigration enforcement cost Cook County businesses an estimated $1.26 billion in lost sales last year as Latino residents sharply curtailed trips outside their neighborhoods to shop and dine.

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Sep 8 • 2:32 PM EDT • Politics • chicagobusiness.com
Bills Mafia’s Houston takeover: Where to party before Bills-Texans

Here’s all the information you need if you’re traveling to Houston for Bills vs. Texans

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Sep 8 • 2:00 PM EDT • Sports • sports.yahoo.com
Pritzker, Eyeing 2028, to Help Midterm Democrats With a $20 Million Group

JB Pritzker, the billionaire governor of Illinois, is continuing to expand his national footprint, this time by using a new group to target Republicans in battleground races.

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Sep 8 • 1:20 PM EDT • Politics • nytimes.com
Apple Falls Before Ternus's First $54 Billion iPhone Test

Tomorrow's launch must turn premium hardware into evidence that Apple can close its AI gap.

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Sep 8 • 12:51 PM EDT • Technology • finance.yahoo.com
Roundtable Rams Episode 34

Roundtable Rams crew James Brizuela and Billie Melissa break down the Los Angeles Rams Week 1 showdown with the San Francisco 49ers.

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Sep 8 • 12:48 PM EDT • Sports • sports.yahoo.com
Your vote. Your child’s classroom. Your electric bill. Your water. Your health.

More than 95% of cases in this country are handled by state courts. And as the U.S. Supreme Court pushes fundamental questions about our freedoms back to the states, state courts and state constitutions are increasingly important protectors of our rights.But those protections only mean something if the judges sitting on our Supreme Court are willing to enforce them.

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Sep 8 • 11:47 AM EDT • Health • ncnewsline.com
Norman Rock Creek Entertainment District faces lawsuit over tax increment financing

Norman's Rock Creek Entertainment District is a $1 billion project set to open in 2028, including a multipurpose performance venue, restaurants, retail space, office development, a hotel, and multiple housing options.

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Sep 8 • 11:25 AM EDT • Entertainment • news9.com
Rock Creek Entertainment District in Norman faces another legal battle

A judge will hear arguments on Tuesday as the legal battle over the $1.1 billion Rock Creek Entertainment District in Norman heads back to court.

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Sep 8 • 10:53 AM EDT • Entertainment • koco.com
Louisiana concrete companies join forces to capitalize on construction boom

Two Louisiana concrete suppliers are joining forces with two out-of-state companies to pursue large-scale construction projects as billions of dollars in new industrial and technology investment move … Already an INSIDER? Sign in. Already an INSIDER? Sign in

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Sep 8 • 10:52 AM EDT • Business • businessreport.com
UnitedHealth’s Democrat investment, and surprise billing bloat debate

UnitedHealth execs shower a top Democrats with cash, and the No Surprises Act debate heats up.

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Sep 8 • 10:51 AM EDT • Health • statnews.com
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD

With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.

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Sep 8 • 10:50 AM EDT • Science • fiercebiotech.com
Corning Stock Climbs On Multibillion-Dollar Verizon Network Deal

Corning stock rose after the provider of optical communications gear for telecom networks announced a multi-billion agreement with Verizon.

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Sep 8 • 10:41 AM EDT • Business • investors.com
Canada’s retaliatory tariffs take effect as US trade talks stall

Canada enforces $20 billion in retaliatory tariffs on U.S. goods after trade talks collapse, escalating tensions in the North American trade dispute.

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Sep 8 • 10:39 AM EDT • Business • virginiabusiness.com
Mistral raises €3B as sovereign AI becomes big business

The French AI lab has raised €3 billion at a €21 billion valuation in a Series D round led by Samsung, Scaleup Europe and PSG Equity.

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Sep 8 • 10:17 AM EDT • Business • techcrunch.com
The Latest: Canada strikes back with tariffs on about $20 billion worth of US goods

Canada struck back at U.S. President Donald Trump on Tuesday with tariffs on about $20 billion worth of U.S. goods, in response to his latest round of tariffs on Canada.

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Sep 8 • 10:13 AM EDT • Politics • ksat.com
He lost $180K in retirement savings, now drives Uber and Lyft at 58

Bill Lewis, a former Wall Street broker, now drives for Uber and Lyft after losing his retirement savings in a failed franchise venture.

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Sep 8 • 9:43 AM EDT • Business • businessinsider.com
More than 1.6 million people die each year from secondhand smoke

The share of the population exposed to tobacco smoke is falling, but more than 2.7 billion people worldwide are still affected

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Sep 8 • 9:11 AM EDT • Health • english.elpais.com
Explainer: Why Air India's funding call has come under political scrutiny in Singapore

Air India's request for about $1.5 billion in funds from its owners — Tata Sons and Singapore Airlines — has sparked a debate in Singapore over state investor Temasek's exposure to the Indian ​carrier.

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Sep 8 • 9:05 AM EDT • Politics • reuters.com
Joel Pollak on LA homelessness, Gavin Newsom's bills

California Post opinion editor Joel Pollak joins Cheryl Casone to discuss Mayor Karen Bass being pressed on Los Angeles homelessness spending, President Donald Trump's tax incentives for Hollywood and Governor Gavin Newsom's progressive bills.

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Sep 8 • 9:02 AM EDT • Business • foxbusiness.com
FOX Sports’ Nick Wright eviscerates Bills’ Josh Allen for lack of signature win

Josh Allen doesn't have a signature win according to Nick Wright.

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Sep 8 • 9:02 AM EDT • Sports • sports.yahoo.com
Endorsement: No on Proposition 44, a cynical attack on community health clinics

Californians must not fall for SEIU-UHW’s thuggish tactics. Vote no on Proposition 44.

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Sep 8 • 9:00 AM EDT • Health • ocregister.com
Science ministry to inject $3.49 bl for AI model

South Korea's science ministry plans to invest 4.7 trillion won ($3.49 billion) for a project to develop a homegrown artificial intelligence (AI) model that wil

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Sep 8 • 8:29 AM EDT • Science • koreaherald.com
What to know about Canada’s trade war with U.S. as tariffs take effect

Canada struck back at U.S. President Donald Trump on Tuesday with tariffs on about $20 billion worth of U.S. goods, in response to the latest round of tariffs on Canada

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Sep 8 • 8:25 AM EDT • Politics • spectrumlocalnews.com
What to know about Canada’s trade war with U.S. as tariffs take effect

Canada struck back at U.S. President Donald Trump on Tuesday with tariffs on about $20 billion worth of U.S. goods, in response to the latest round of tariffs on Canada

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Sep 8 • 8:25 AM EDT • Politics • spectrumlocalnews.com
Science ministry to inject $3.5 bil. to develop frontier AI model

Science ministry plans to invest 4.7 trillion won ($3.49 billion) for a project to develop a homegrown artificial intelligence (AI) model that will...

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Sep 8 • 8:04 AM EDT • Science • koreatimes.co.kr
Tyson Cuts Outlook as U.S. Cattle Shortage Hammers Beef Business

Photo credit piter2121 - stock.adobe.comTyson Foods lowered its fiscal 2026 profit and sales forecasts Thursday as the historically tight U.S. cattle supply continues to pressure meatpackers. The company now expects adjusted operating income of $1.85 billion to

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Sep 8 • 8:00 AM EDT • Business • americanagnetwork.com
Canada's 20% tariffs on US goods like milk, steel and golf clubs take effect

President Donald Trump threatened to ban Bombardier aircraft sales on Truth Social just hours before Canada's retaliatory tariffs hit $20 billion in U.S. goods.

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Sep 8 • 7:44 AM EDT • Politics • foxbusiness.com
Eureka Springs Police Chief creates unique system for enforcing the rules of the permanent entertainment district trial

To make understanding this trial easier, Eureka Springs Police Chief Billy Floyd set up a patrol checklist to track disturbances and how many times they’ve had to remind people of the rules.

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Sep 8 • 6:47 AM EDT • Entertainment • ky3.com
Eureka Springs Police Chief creates unique system for enforcing the rules of the permanent entertainment district trial

KY3's Billie Brightman reports.

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Sep 8 • 6:46 AM EDT • Entertainment • ky3.com
EBUGs, dress code, other changes the NHL, NHLPA are monitoring as new CBA takes effect

Deputy commissioner Bill Daly and union boss Marty Walsh tell The Athletic what they're watching under the new CBA.

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Sep 8 • 6:00 AM EDT • Sports • nytimes.com
The strong summer may be a good sign for theaters this year

Hollywood's biggest summer box office ever, powered by "The Odyssey" and "Spider-Man: Brand New Day," has analysts betting on a $10-billion year.

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Sep 8 • 6:00 AM EDT • Entertainment • latimes.com
Everything to know about Lucas Museum of Narrative Art

The highly anticipated $1-billion building opens Sept. 22. Learn more about its architecture, must-see experiences, rocky start and the questions surrounding "narrative art."

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Sep 8 • 6:00 AM EDT • Entertainment • latimes.com
Roma slash 26/27 wage bill by 14%

Roma, as stated by Tony D’Amico, has lowered its wage bill as requested by UEFA to send a positive message to European football’s governing body. The Roman club is moving toward sustainability, wh...

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Sep 8 • 5:30 AM EDT • Sports • sports.yahoo.com
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Buffalo Bills WR Predicted to Have Career Year in 2026

The Buffalo Bills could see one of their young offensive weapons take a major step forward in 2026, with a bold prediction pointing toward a career year for Keon Coleman. The second-year wide receiver enters the season with an opportunity to establish himself as a more consistent and productive target in Buffalo’s passing attack. Coleman […] The post Buffalo Bills WR Predicted to Have Career Year in 2026 appeared first on Gridiron Heroics.

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Sep 8 • 5:14 AM EDT • Sports • sports.yahoo.com
$68 billion is up for grabs in Medicaid. Who wants it?

What would you do with $68 billion? That is the size of the decision Indiana is about to make.

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Sep 8 • 5:00 AM EDT • Health • indianacapitalchronicle.com
The Market Forces Quietly Adding Thousands to Patient Bills

The true cost of “vertical integration”: patients directed to a higher-priced location for procedures. Or forced to buy from their insurer’s wholly owned pharmacy, which may not stock the drug prescribed or provide it at the lowest price.

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Sep 8 • 5:00 AM EDT • Health • kffhealthnews.org
Now is perfect time for Sebastian Tounekti to step up

Time for Sebastian Tounekti to step up. It’s essentially now or never for Celtic’s inconsistent Tunisian winger…5th September 2026; The Marbill Coaches Stadium, Paisley, Scotland; Scottish Premi...

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Sep 8 • 4:45 AM EDT • Sports • sports.yahoo.com
Health experts, lawmakers push for Pa. kratom regulation; proponents warn they'll fight a ban

In Pennsylvania, kratom and more potent, related products remain legal. There are multiple bills moving through the statehouse that would ban or regulate them. But researchers warn there’s still a lot we don’t know.

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Sep 8 • 4:31 AM EDT • Health • penncapital-star.com