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‘It’s just important to stay healthy’: Dozens of former NFL players attend health screening
Dozens of former professional football players turned out for a health screening on Saturday, encouraging others to get regular doctor checkups and to stay active. Troy Davis is 35 and spent two years in the National Football League playing for the New York Jets and Dallas Cowboys. “As you age, health things start to pop up.”
Trump accelerates research on psychedelic treatments and asks, ‘Can I have some?’
President Donald Trump on Saturday signed an executive order aimed at encouraging expanded research into ibogaine and other psychedelic drugs, part of a broader push to explore emerging mental health treatments.
The Help That Many Older Americans Need Most
With shortages of medical professionals and an aging population, thousands of community health care workers prevent older adults from falling through the cracks.
It doesn’t matter how much you sit — walking more could lower your risk of death and disease
Sitting all day might not be as damaging as once feared—if you’re willing to move more. A massive study tracking over 72,000 people found that simply increasing daily steps can significantly reduce the risk of death and heart disease, even for those who spend long hours sedentary. Hitting around 9,000–10,000 steps a day delivered the biggest benefits, cutting mortality risk by nearly 40% and cardiovascular disease by over 20%.
Six Everyday Habits That Can Help Prevent — And Sometimes Reverse
Advance Community Health is encouraging a shift in how chronic disease is managed, focusing on prevention through six everyday habits like nutrition, movement, sleep, and stress management. Providers say small, consistent lifestyle changes can help patients take control of their health — and in some cases, even improve or reverse conditions like diabetes and high blood pressure
4 Activities To Boost Brain Health While Sitting Down
In TODAY.com's Expert Tip of the Day, learn how to make your time spent sitting less damaging for your brain.
What is the femosphere?
A growing number of influencers are encouraging women to ditch the egalitarian narrative of liberal feminism and take a more cynical approach to the opposite sex
'Allies, not vassals': How Meloni's break with Trump became a political moment for Italy
Italian Prime Minister Giorgia Meloni is managing the repercussions of a public rebuke from US President Donald Trump this week over the pope, Iran and a defence deal with Israel. It's a rupture that…
Stony Brook Medicine Spotlights Advances in Brain Health and Aging
President Andrea Goldsmith attended a series of presentations led by Stony Brook Medicine researchers, who shared emerging insights into brain health and aging.
Columbus Business Beat: Capitol Square plan on pause, The Little Bar demolition
COLUMBUS, Ohio (WCMH) – This week on Columbus Business Beat, Digital Anchor Rachel Ramsey talks to Mark Somerson, Managing Editor of Columbus Business First, about business news across ce…
Redefining health and value as we age
Explore Mayo Clinic’s Aging Forward podcast with Sir Muir Gray on healthy aging—fitness, prevention, self-care, and community support for longevity and purpose.
Lainey Wilson on Managing Mental Health After a Days-Long Panic Attack and Why She Once Had 3 Therapists (Exclusive)
Lainey Wilson opens up about her mental health journey and the importance of speaking up in this week's PEOPLE cover story. She also shares why she had three therapists at one point and the time she experienced a days-long panic attack.
Ionic Studios Signs Electric Entertainment's ELECTRIC NOW/ ELECTRIC NOW EN ESPANOL FAST/ AVOD APP, Featuring Leverage, The Librarians, and The Ark to Its CTV Portfolio
Ionic Studios, the CTV studio for the open ecosystem, today announced a strategic partnership with Electric Entertainment, the Los Angeles-based production and distribution company, founded by Dean Devlin. Under the agreement, Electric's content will join Ionic serving as brand-level representative across CTV and FAST—merchandising the studio's streaming platforms, ENOW and ENOW EN ESPANOL to advertisers, packaging it into audience-defined offerings, and delivering the buying standards that medi
Scientists remove “zombie” cells and reverse liver damage in mice
A rogue set of “zombie” immune cells may be driving aging and fatty liver disease by flooding tissues with inflammation. Researchers found these cells accumulate with age and high cholesterol—and can make up most of the liver’s immune cells in older mice. When scientists removed them, liver damage was dramatically reversed, even without diet changes.
Ohio readies $5M fine against Kalshi for unlicensed sports betting: Capitol Letter
The prediction market operator is waging a multistate battle over whether its sports offerings should be treated as state-regulated gambling or federally regulated financial swaps.
Chicago IP firm Marshall Gerstein names first new managing partner in 24 years
The election of Randall Rueth comes amid an explosion in the field of patent law and as artificial intelligence transforms the legal industry.
The 5 key biomarkers that can tell you how well you're aging — the most crucial is the most overlooked
The 2026 International Academicians Hong Kong Forum Held in Hong Kong, Focusing on AI-Driven Innovation in Health and Higher Education
The 2026 International Academicians Hong Kong Forum, jointly organised by the International Alliance of Academicians (IAA) and the Hong Kong Association of Overseas-Returned Scholars (HKAORS), was successfully held in Hong Kong on April 14. As one of the major events of the Business of Innovation and Technology Week 2026, the Forum focused on two core themes: "Aging and Chronic Disease Management: Challenges and Innovations" and "AI and Innovation in Higher Education." It brought together more t
You’re Not Unlucky—Your Brain Is Sabotaging You. But There’s a Way to Claw Back Control, Scientists Say.
Multiple studies show it’s possible to “hack” your mind to improve your luck. Here’s how to do it.
Radiology Business Management Association elects new board members
Stacy Sanso—director of patient access for ARA Diagnostic Imaging, the Austin, Texas, affiliate of Radiology Partners—takes over as president of the association.
Beyond the Dialysis Machine: Shaping the Future of Kidney and Cardiovascular Health
At Yale School of Medicine, Christopher El Mouhayyar, MD, works at the forefront of managing dialysis treatment in patients while addressing underlying disease.
Radiology Business Management Association names new board of directors
Stacy Sanso—director of patient access for ARA Diagnostic Imaging, the Austin, Texas, affiliate of Radiology Partners—takes over as president of the association.
SB 1397: Better Science = Better Policy
Managing California’s majestic mountain lion population, particularly in areas of conflict with areas where humans...
Apple Launches New All-in-One Apple Business Platform for Device Management, Email, and Customer...
Apple today launched its new all-in-one Apple Business platform, debuting the refreshed Apple Business web portal and accompanying app. Apple Business aggregates several of Apple's prior business-focused products, like Apple Business Essentials, Apple Business Manager, and Apple Business Connect. The service offers organizations a unified platform for managing devices, employees, communications, and customer engagement across the Apple ecosystem.
Adopting, advancing and adapting to AI
In Penn State's Eberly College of Science, researchers are leveraging AI in a myriad of applications and instructors are finding innovative ways to incorporate AI into their classrooms. But what is artificial intelligence, and are people really talking about the same thing when they say AI?
Simon Cherry Receives ESMI Award for Significant, Long-Term Contributions to Imaging Science
The Distinguished Research Professor of biomedical engineering has received the 2026 ESMI Award from the European Society for Molecular Imaging. Among the most prestigious honors in imaging science, the award celebrates a researcher for their outstanding contributions to the interdisciplinary field.
Candy now tastes different. It’s not just you.
From recipe changes to aging taste buds, here's why those peanut butter cups don't hit like they used to.
Scientists reverse brain aging, with a nasal spray
New therapy is turning back the clock in aging brains, healing inflammation, restoring memory and reshaping the future of brain age-related therapies.
The business of being Rachel Zoe
This week, I checked in on Rachel Zoe’s return to the spotlight and how she's leveraging value of the “Real Housewives” empire.
YouTube viewers can now work together to stop ads from playing
YouTube is letting viewers combat ads by banding together and engaging in chat to keep ads from playing.
Imaging science research gives new clarity on what color helps eyes focus best
Research by RIT assistant professor Benjamin Chin published in Science Advances may help determine which wavelengths helps the eye focus best.
Artificial sweeteners: Why the science war is raging on
Conflicting studies on artificial sweeteners are fuelling fresh debate across food and drink, as health risks, regulation and reformulation collide worldwide.
From dumplings to pickleball, check out these new North Jersey shops
Ugly Dumpling, Open Play Pickleball, a health care imaging clinic and a Khaadi fashion store at American Dream make our latest list of new businesses.
TCU Nutritional Sciences Expert Discusses New US Dietary Guidelines
As updated federal recommendations roll out, Samantha Davis highlights gaps between science and messaging.
FDA accepts previously rejected application for new PET imaging agent
The radiopharma firm hopes to soon begin selling Pixclara (Floretyrosine F 18), an investigational product for glioma, a type of brain cancer.
Curtis Blaydes suffered multiple significant facial injuries at UFC 327
Engaging in a “Fight of the Year” candidate took its toll on Curtis Blaydes.
Barron Trump’s beverage brand unveils first flavors ahead of launch
Barron Trump-linked beverage startup SOLLOS is teasing its first yerba mate flavors and packaging as the company builds momentum ahead of its planned May 2026 launch.
Scientists were wrong about lifespan. Your genes matter way more than we thought
For years, scientists believed our lifespan was mostly shaped by environment and chance, with genetics playing only a minor role. But a new study from the Weizmann Institute flips that idea on its head, revealing that genes may actually account for about half of the differences in how long people live. By analyzing massive twin datasets—including twins raised apart—and using innovative simulations to filter out deaths from accidents and other external causes, researchers uncovered a hidden genetic influence that had been masked for decades.
Scientists Capture Hidden Electron Patterns Inside Quantum Materials
A new imaging technique uncovers how electronic patterns in quantum materials evolve unevenly across space and temperature.
Gary Woodland takes another step at managing mental health at Masters
Gary Woodland believes he took another step toward managing his mental health issues. "Today was peaceful," he said after a 66 in final round of the Masters.
As WhatsApp faces lawsuit, Elon Musk launches 'no tracking' messaging app XChat
App will offer encrypted chats, voice and video calls, large group messaging and disappearing messages, initially for iPhone and iPad users only, with no ads or phone number required to sign up
Deion Sanders gives encouraging health update at Colorado spring game
Deion Sanders returned to the field for the Buffaloes' spring game after dealing with blood clots, and he provided a positive update on his health.
Go ahead and grab that glass of wine — it can slow biological aging, but there’s a catch
Bird brain: New study finds birdwatching may boost brain health, slow cognitive aging
A simple look out the window at your favorite bird could do more than brighten the day. In fact, according to a recent study, it may help keep the brain sharp.
As Swalwell’s campaign unravels, his rivals in California governor’s race scramble for an opening
The sexual misconduct allegations against Rep. Eric Swalwell are damaging his hopes of winning the governor’s race, with former allies revoking their endorsements and a growing list of prominent Democrats telling him to withdraw.
I grew up in a family of entrepreneurs. Here’s what I had to unlearn to build a $1 billion business
I grew up in Switzerland surrounded by entrepreneurs: my grandfather in construction, my father in surveying, my uncles in packaging and construction.
The most important Democratic health care debate is raging again
Single payer is getting a second wind.
Bridging Oral Health and Integrated Care: A Scientometric Study of Integrated Care for Older People (ICOPE) and Removable Prosthodontics in Older Adults
Population aging has shifted healthcare priorities from disease-centered models towards functional ability and quality of life. The WHO Integrated Care for Older People (ICOPE) framework operati...
ON THE JOB: “What is the Best Business Advice You’ve Ever Received?
Interviews by Deborah Jeanne Sergeant Sound advice can contribute to your success. We recently asked area business leaders, what was their best advice they’d ever received. Here’s what they said: “The best advice I ever received was from my then –boss, Gerry Church, Fulton plant manager at Miller Brewing Co. He told me that whenever I wanted to discuss a business problem or issue with him, I should also be prepared to offer possible solutions. It’s the difference between being proactive or reactive. It’s also the difference between being a leader or follower. That has served me well in any business relationship I have had since then.” — Stephen Chirello, Owner, Steve Chirello Advertising, Fulton “Someone will always do it for less; they will also take the most effort to service or satisfy and leave you for the next lower price.” — John M. Henry, Owner, Speedway Press, Mitchell Printing, Phoenix Press, Oswego “I’m going to answer this question by turning it around and giving my own advice that is, ‘Always treat every customer as if they were your only customer!’ We are celebrating our 50th anniversary in business this year. We started our business on March 25, 1976. My advice works.”” — Nick Chervinsky, President, Brewerton Pharmacy, Brewerton “’You need to toot your own horn, my grandfather, Howard D. Dice, told me.” — Beth Ann Dice, Women’s active aging and cancer recovery coach, Mission Movement Wellness Studio & Breast Cancer Recovery Studio, Fulton “In the micro enterprise class, they taught, ‘Get a good lawyer, accountant and bank.’ That was over 30 years ago and I still have those three today. I chose good people I could grow with.” — Tony Pauldine, Owner, Anthony M. Pauldine General Contractors Inc., Oswego “From my grandfather; ‘Listen to everyone! You never know where you will get the solution you need.’” — Kevin Dean, Executive director, Oswego County Opportunities, Fulton “‘Preparation is the mother of success.’ My dad always drilled that into my head growing up, and it has helped me avoid a lot of snags in both my personal and professional life. Thanks, Dad!” — Bekkah Frisch, Owner and president, iHeart Holdings, Inc., Fulton “If you don’t take a risk and try, you will never know.” — Justin Taber, Owner, Torbitt’s Service Center, Oswego “Be ready to take a loss.” — Cody Seymour, Manager, Damiano’s Eatery, Mexico “I’ve received so much good business advice over the years. When people are giving you advice, always be curious rather than judgmental. Follow your gut. Doing the right thing is never the wrong thing.” — Dana Decker, Principal owner/broker, Berkshire Hathaway Home Services, Oswego ’Do it and figure it out later.’ It hasn’t failed me yet. Too many people take time to think about doing this and this and this and then the opportunity is over with. If it’s somewhat reasonable — if it’s not something outrageous — do it and figure it out later.” — Jeremy Allen, Licensed real estate salesperson, Acropolis Realty Group, Syracuse “’Try to meet the needs of the customer. Treat them like you’d like to be treated.’ It’s like the Golden Rule says.” — Douglas Dickson, Physician and associate at CNY Foot Surgery and Podiatry Care, East Syracuse “The best piece of business advice I’ve ever received applies to life in general: always be honest. Never overstate your capabilities and always be willing to ask questions. The more specific you can be in any given topic will always lead to a better outcome.” — Tom Fernandez, President, Woodbine Hospitality, Syracuse “As a business owner, the advice would be ‘Don’t overextend yourself. Especially in agriculture, expect issues to come up.’ If something is going right, it’s not true agriculture. This last season, we scaled very hard to field another crew. We got more drones, crew and generators based on projections. This last season hit the ag community hard with a very wet spring. We did 15,000 to 20,000 acres for fungicide and the same for cover crop seeding in 2024. We scaled to 25,000 to 30,000 for 2025. We ended up doing 2,000 for fungicide and 3,000 for cover crop seeding. That’s why that advice was good.” — Rick Jordan, Operations manager, CNY Drove Services, Clinton “’Keep your head down, mind your own business and do the best for your clients that you can do.’ It has a lot to do with my success in working for Galloway Century 21.” — Ed Fayette, New York state licensed real estate agent, Century 21 Galloway, Oswego “’Expand in all ways, always.’ It just keeps you going and keeps you growing.” — Stephen Baier, Licensed real estate person, The Real Estate Agency & Bouck Commercial, Auburn “The best advice is, ‘Your biggest asset you won’t see on the books because it comes from your employees.’” — David Flickinger, Owner, Edible Arrangements, Syracuse “Don’t take things personally when you’re working with the public.” — Leeann Desimone, Manager, Annie’s Hallmark Shop, Auburn “‘Follow up.’ The customer knows that you care about what you are doing and that their opinion counts. Sometimes they might be on the fence about whether they want to use your company. If they’re asking your opinion on things, they feel you are concerned about what you’re doing. They like to be kept in the loop if they’re spending money with you.” — Dorothy Casper, Saslesperson, SweetWoods Memorials, Phoenix “The best business advice I received is ‘Never be the smartest person in the room. Surround yourself with people who are smarter than you.’ That’s how you learn.” — Debbie Bilello, Owner, Virtual Office Solutions, Central Square “’You need to grow your business but you can’t grow too big too fast.’ That’s what we’ve done at Pinnacle Maintenance. We’ve tried to grow but not too fast. Along those same lines, there’s another good piece of advice, ‘Don’t take on more than you can handle because it only leads to a bad name for your business and a bad experience for your customers.’ It goes along the same lines as growing your business slowly and carefully.” — David Wines, Owner, Pinnacle Maintenance, Central Square “Always be on time and do what you say you are going to do.’ I’ve done very well following that advice. Most of my work is referral and I don’t really do any advertising so I have a pretty good customer base. It’s mostly word-of-mouth from satisfied customers.” — Robert J. Fleming, Owner, Bob Fleming Windows & Doors, Brewerton “’Concentrate on your finances, always pay your taxes, and form a team you can depend on. Try to help the community you’re in as much as you can.’ We do all of these all the time here. We give and give and give to the community and the community gives back to us always.” — Susan Bonnet, Co-owner, Bonnet Sales and Service, Central Square “Keep smiling. It brings a positive attitude to the workplace.” — Karin Lindsley, Vice president, DTS Truck Service, Syracuse “‘Customer service above all.’ Following this advice has served us very well.’ — Guy Fox, Owner, Fox’s Discount Parts, West Monroe “The best thing to do is to make sure you’re taking in more money than you’re spending. I wish I could say I’m a good businessman but I have been in business since 1981. I’m not a bean counter but work well with my hands and its’s served me well all these years and I am still in business.” — Matt McGill, Owner, Matt McGill Collision, Brewerton
“AI polls” are fake polls
A few weeks after Donald Trump’s second presidential win, I took the train up from London (where I was living at the time) to Oxford to attend a conference on polls and forecasts of the 2024 election. Most of the attendees were pollsters or academics, but I also watched presentations from Aaru and Electric Twin, two companies that do what is interchangeably called synthetic sampling, silicon sampling, or synthetic audiences. Stripped of startup jargon, that means they use large language models (LLMs) to simulate responses to public opinion polls by having AI agents take on the role of survey respondents. I had already heard of Aaru thanks to some articles with eye-catching headlines like “No people, no problem: AI chatbots predict elections better than humans” in the months leading up to Election Day. The founders were making some big, some might even say far-fetched claims, such as: “within two years, we will simulate the entire globe — from the way crops are grown in Ukraine to how that impacts production of oil in Iraq, trade through the strait of Malacca, and elections for the mayor of Baltimore.” When Semafor asked Aaru’s cofounders — Cameron Fink and Ned Koh — about my boss, they said “we respect all those who came before us.” Nate (as he so often does) shared his thoughts on Twitter: Fink and Koh were relatively good-natured about this back-and-forth when we spoke at Oxford. They even offered to mail me one of the t-shirts featuring Nate’s quote they apparently had made. I never took them up on the offer, which I now somewhat regret. These synthetic sampling companies fell off my radar for a while, but they do still exist. In fact, Aaru recently received a $1 billion valuation. Is what they’re doing anywhere close to the most important frontier in AI development? Not by a longshot, especially when Anthropic just developed a model so adept at exploiting software vulnerabilities that it’s only being released to 40 companies. Still, silicon sampling is increasingly finding its way into public polling. Axios reported in March that “a majority of people trust their own doctors and nurses” based on findings from Aaru — without mentioning that the “people” in that sentence were actually LLMs. Around the same time, the Public Sentiment Institute “boosted” their online sample of 373 real survey respondents with 114 AI agents.1 (Spoiler alert: even the co-founder of Electric Twin doesn’t think that’s a particularly defensible approach.) Polling companies like Qualtrics and Ipsos are also developing synthetic data panels. So, what should we make of these … “polls”? Let’s get one thing out of the way: whatever they are, they’re not polls in the way that term is usually defined. Subscribe You can’t replace polls with AI On one hand, using LLMs to essentially make up fake survey respondents sort of sounds like the dumbest idea ever, one that will at best imperfectly replicate real polls while introducing all sorts of biases. On the other hand, with LLMs improving at a remarkable, perhaps even alarming rate, maybe that means I’m a dinosaur at the ripe old age of 24 because I still want to rely on polls that talk to actual people. I’m not going to argue that synthetic samples are completely useless. In fact, as I’ll return to later, there is evidence that some techniques can replicate topline survey results quickly and cheaply. But the marketing from certain companies can be slightly optimistic. “No traditional poll will exist by the time the next general election occurs,” said Fink in 2024. We’re just 206 days away from the midterms, and based on the fact that I still have to collect a bunch of polls every day, I’d say he should have run that prediction by a sample of AI agents before the interview.2 To see why synthetic samples can’t replace polls, here’s a quick primer on how they work. The simplest version of these models involves taking a LLM (like ChatGPT or Claude), giving it a demographic profile (e.g., a white, college-educated woman who lives in Utah and makes $70k a year), and then asking it to respond to a survey question. You repeat that process a few thousand times using different demographic profiles and end up with a sample of synthetic survey responses. The actual models used by private companies are more sophisticated than this, usually because they incorporate more hypothesized demographic characteristics for each agent and provide them with extra information. Aaru, for example, feeds agents a diet of news and information they’d be likely to consume, while Electric Twin incorporates their customers’ proprietary data about the audience they’re trying to replicate. The way Ben Warner, the co-founder of Electric Twin, explained it to me was “we have a large amount of data on […] for instance, 5,000 people. Can we make an accurate prediction of how they would respond to another question?” Still, it should be obvious why synthetic samples can’t replace polls. Polling is fundamentally a data collection process. We might use surveys to make predictions by feeding them into election forecasts, but the main purpose of a poll isn’t prediction, it’s gathering new data about what people think and how they feel. Silicon sampling, on the other hand, produces no new data. It’s simply a model: you input LLM training data, demographic prompts, and a bunch of other information, and it spits out a prediction for what a poll would say. We love models here, but models aren’t polls. That difference is an important philosophical sticking point for most pollsters I talk to. “I think politics should stay away from [synthetic sampling], because we’re trying to […] represent the voice of the people,” said Natalie Jackson, a vice president at GQR Insights. Democratic pollster John Hagner told me: “I think I’m just incredibly skeptical of this idea. I don’t think it’s research. At that point, you’re asking the machine to tell you what you already believe.” Hagner has seen some presentations of early synthetic sampling experiments, but so far, “if it’s being used in a campaign, people are keeping it incredibly quiet.”3 But Eli, I hear you saying, aren’t polls themselves increasingly governed by modeling decisions? Indeed they are: pollsters’ choices on which sampling method to use, how to define their likely voter models, and how to weight their samples can and do lead to dramatic differences in the results they publish. Aaru even referenced these limitations in the methodology statement included with that maternal mortality “poll” — although I’m using the term “methodology statement” loosely here, because it doesn’t really explain how the model works at all. We can ignore the (frankly preposterous) implication that synthetic sampling isn’t subject to a separate set of biases. The important point is that there’s still a meaningful difference between using weighting and other statistical techniques on actual polling data and using a model to predict what a poll would say. The latter is far closer to election forecasts or techniques like MRP — potentially useful models, but not a replacement for polls.4 To be fair, other synthetic sampling companies are perfectly happy with the distinction between polls and models. Warner compared polling and synthetic sampling to different tools in a toolbox. “The mistake I think we make is we think that these new tools should either work in exactly the same way or somehow replace these old tools,” he said. “Rather than thinking of it as, okay, so we’ve always had the hammer, we’ve always had the screwdriver, now we’ve got a saw. But don’t use a saw to try [to] do the job of a hammer.” A quick comment from Nate Eli didn’t ask me for a comment — rather rude of him, don’t you think? But since I’m editing this story, I figured I’d add a few quick thoughts rather than putting words in his mouth. Beyond the frequently misleading marketing, what bothers me about the AI “poll” hype is that as AI tools make statistical inference cheaper and/or better (note that these are not synonyms) that actually increases the comparative value of collecting original data. You might be able to train a model to make a reasonable estimate of what some hard-to-reach poll respondent would say — say, a young Black man who voted for Trump. (Such a person checks a number of boxes for a voter who is usually hard to reach in surveys.) Indeed, this is closely related to what models like the Silver Bulletin forecast already do. They essentially smooth out the kinks in noisy survey data by making inferences based on past voting patterns or national polls or surveys of other states. But you don’t actually know what these voters think unless you’re reaching them directly. If there’s a shift in opinion among this subgroup, you’re not going to detect it. So if I were running a campaign, I’d invest more in going the extra mile to find a representative sample of those voters. And then I’d hire some smart quants — or Claude? — to figure out the implications for campaign strategy based on proprietary data that my competitors didn’t have access to. -Nate Silver Are these models any good? If synthetic surveys are just a new type of model, the next obvious question is whether the models are at least accurate. The answer very much depends on who you ask. On one end of the spectrum, you have the maximalist argument that synthetic sampling is more accurate than actual polls. “It’s an incredibly challenging problem to go to someone and say ‘hey, we’re going to be more accurate at predicting human behavior than you, even when you talk to your customers directly’,” Koh recently told CNBC. In his view, synthetic sampling isn’t a saw to polling’s hammer, it’s “magic.” There’s certainly evidence that synthetic samples can replicate certain survey toplines. But if Aaru does have any examples of their approach outperforming the polls, they’re keeping those to themselves.5 Aaru’s 2024 election model, for example, had Kamala Harris leading in Michigan, Nevada, Pennsylvania, and Wisconsin on November 4th. And although they’ve since taken down their forecast page, they gave Harris a 50.5 percent chance of winning the race on November 2nd.6 After the election, Fink told Semafor he was happy enough with those results because they were “within margin of error,” a term that is completely meaningless when applied to a “sample” of AI agents. And of course, Aaru says their models have improved since 2024, so supposedly now they’d be more accurate than the polls? Still, their stronger argument is on cost: “We are significantly faster and cheaper than traditional polling, and still more accurate,” said Fink. The first two claims are undeniably true, but the third brings us to the opposite end of the spectrum. Both Jackson and Hagner are skeptical that these models are reliable for anything beyond replicating common survey toplines. “I just […] don’t think the machines are what we want when we’re looking for nuanced views. My example on this is people in Arizona and Nevada in 2024 who voted for Trump and voted for expanding abortion in their states on ballot initiatives,” said Jackson. Hagner identified another issue. Maybe the synthetic respondents, like sycophantic LLMs, are inhuman in one important way: they’re too nice. “The reports that have come through at the meetings that I’ve been at are that the early experiments on this, they cannot get respondents to be as racist or sexist or, frankly, as negative as human respondents,” he said. Academic research mostly agrees on this point. While there are some papers that show promising results when using LLMs to replicate polling data, most show that LLMs suffer from various quirks like producing too few “don’t know” responses and can seriously overpredict the favorability of politicians like Donald Trump and Kamala Harris. They also seem to struggle with too little variation between demographic subgroups, so the difference in predicted opinion between Democrats and Republicans, for example, is too small. When I asked Warner about these studies, his response to these papers was that just because academics can’t get synthetic sampling to work doesn’t mean that the technique doesn’t work in general. “Actually, the argument is, okay, yours does not [work]. That does not mean […] for this complex set of machinery, which uses a lot of investment, a lot of time, a lot of money, you can’t get it to work.” Cards on the table, I’m somewhat sympathetic to this argument because academics aren’t exactly great at making election forecasts. Usually, the people with skin in the game are the most accurate. Warner’s argument is that the approach Electric Twin takes — which includes, for example, making multiple predictions for each synthetic respondent using different models and prompts and subsequently averaging those to get a final prediction in a sort of ensemble forecast — produces better results than the simpler academic models. Warner shared a comparison between his method and the method from a recent academic paper with me, and Electric Twin was indeed able to get more accurate replication. But even still, he acknowledged that synthetic sampling “is not a crystal ball.” “If you asked me, do I think using other data sources will be more accurate than asking somebody who they will vote for, I would probably say no. But if you asked me ‘would your system be useful for our turnout modeling today?’ I would say yes.” For better or worse, it looks like the method is already getting more popular in the market research world. Most of the clients Aaru touts these days are businesses like EY and McDonald’s. And AI will probably begin to pop up in other parts of the political polling process. Pollsters are already using it to code open-ended survey responses, and some firms, like YouGov, are testing using LLMs to ask survey respondents questions. More worryingly, one danger to actual polls is that AI agents can be used to infiltrate online surveys. Most online polls use various checks to prevent that from happening, but there’s conflicting evidence on how effective those filters are and how prevalent AI agents currently are in online panels. If those agents ever become impossible to detect, it might spell the end of online polling, but the solution isn’t to replace all of your respondents with ChatGPT. Silver Bulletin is a reader-supported publication. To receive new posts and support our work, consider becoming a subscriber. Subscribe 1 That particular poll obviously doesn’t meet Silver Bulletin standards for aggregation. But we exclude all Public Sentiment Institute polls from our averages because we classify them as an amateur polling firm. 2 You could argue that Fink meant the next presidential election, but (a) I’m also confident we’ll still have real polls in 2028 and (b) in that case he should have asked an LLM to define “general election.” 3 Quick caveat: that’s reporting from a Democratic pollster. It’s possible that Republicans are more willing to use AI in political campaigns. 4 Indeed, Silver Bulletin does not include “polls” produced by MRP in our forecasts or averages, and we think it’s extremely misleading when their practitioners describe them in a way that suggests original data had been collected among a large number of states or Congressional districts. 5 A recent report from Aaru and EY did show two examples of a synthetic estimate being closer than a survey to a real-world benchmark — but I’d take those findings with a grain of salt because the report reads more like an ad and didn’t involve any sort of prediction being made ahead of time. 6 For comparison, our odds for Harris on the same day were 48.2 percent.
For aging Supreme Court justices, the politics of retirement looms large
Discussion among experts about a possible Supreme Court vacancy has increased as two men draw closer to the average age of retirement for Supreme Court justices since 2000 and with the November congressional elections looming.
For aging US Supreme Court justices, the politics of retirement looms large
When Donald Trump was asked about the prospect of conservative Justices Samuel Alito or Clarence Thomas retiring, the Republican president voiced his support for the U.S. Supreme Court's two oldest members to remain on the bench.
Best of Bay Community’s Choice Awards business spotlight: Bay Radiology/Women’s Imaging Center
The Best of Bay Community's Choice Awards nominations are open now! It's time to recognize your favorite local businesses.
In praise of popular science
As a kid, I was enthusiastically and unreservedly in favor of a manned space program. Our destiny lay in the stars, I figured. Get people out there. We need Star Trek here and now. As I got older, I became rather disenchanted with the idea. Humans are expensive, fragile, and inefficient as space cargo. We could flood the solar system with 100 robotic probes for the price of any single manned mission and get back just as useful data. Besides, it turns out space travel is dangerous. Tusk is a reader-supported publication. To support this work, please become a paid subscriber. Subscribe When it came to the recent Artemis II mission, my cynical side didn’t really see the point. Flying around the Moon and back is literally something we did before I was born, and I once owned a Members Only jacket. Apollo 8 circled the Moon ten times and returned to Earth safely the same month that “Chitty Chitty Bang Bang” was released. What was the point of repeating a feat that far braver people once did with tin foil and slide rules? Yet I’ve surprised myself with how moving I’ve found the Artemis II mission to be. The photos have been stunning. The crew has been professional and engaging. There have been modest but important milestones — the farthest humans have travelled from Earth; the first woman, person of color, and non-American to leave low-Earth orbit; innovations in communication, and more. One thing that really stood out is that this is really NASA at its finest. Not that this is the most important mission they ever pulled off, but they did this in a competent way that celebrated the achievements and kept the crew and the science at the forefront of the project. This wasn’t some billionaire throwing celebrities or cars into orbit as a vanity project — this was a collective effort to send experts in to do a job and come home safely. We don’t see that sort of thing much these days. I’m guessing few people would describe many government agencies as inspiring, but this one counts for me. We’re living through a profoundly anti-science era, in which pathbreaking, lifesaving discoveries like mRNA vaccines are routinely downplayed or even vilified. As I’ve noted previously, this era is something like that of the Red Scare in the 1940s and 50s, in which “egghead” professors were portrayed as out of touch or even hostile to regular Americans. One of the things that helped break that spell was Sputnik — the Soviet communications satellite that demonstrated that the United States was falling behind in crucial scientific research and applications. Its launch triggered a new appreciation for American science and goaded the federal government into supporting research universities and labs. I’m not saying that Artemis is the equivalent of Sputnik, but it potentially reminds people that there’s some value to scientific endeavors and the human faces attached to them. Despite my love for the show “For All Mankind,” I’m far from convinced that there’s any real value to putting colonies on the Moon or Mars that would justify the capital investment and the massive health risks to the astronauts. But sending scientific good will ambassadors on a trip into space once in a while? Bring it. Share
Melania Trump’s Epstein statement stunned White House aides but was in keeping with a first lady who does her own thing
With war raging and midterms on the horizon, the White House seemed to have finally shaken the Jeffrey Epstein saga that plagued the first year of Donald Trump’s second term. But for first lady Melania Trump, the Epstein story was still all consuming.
XChat, X's standalone messaging app, launching on iPhone and iPad next week
XChat, the standalone messaging app from X, now has a release date. XChat will arrive on iPhone and iPad in...
Scientists say we’ve been treating Alzheimer’s all wrong
Alzheimer’s isn’t just one problem—it’s a tangled mix of biology, aging, and overall health. That’s why drugs targeting a single factor have fallen short, even as new treatments show modest benefits. Scientists are now pushing toward multi-pronged strategies, from gene editing to brain-cell rejuvenation and gut health interventions. The goal: stop treating Alzheimer’s as one disease and start tackling it as a complex system.
Sue Serino Invites Seniors to Learn Laughter’s Health Benefits
Dutchess County Executive Sue Serino and the County’s Office for the Aging (OFA) invite older adults to enjoy an uplifting and engaging afternoon focused on the health benefits of humor at “Spring Into Happiness: Laughter Edition."
Menopause products are having a hot minute. But doctors urge women to be wary of the marketing surge
Women suffering through the hot flashes, night sweats, mood changes and sleep problems that can come with menopause — all while looking in the mirror and noticing signs of aging — are being bombarded with products.
In private meeting, Trump soothes disenchanted MAHA leaders
White House officials solicited messaging ideas from leaders of the Make America Healthy Again movement, which has soured on some recent administration actions.
Central IL author making science more accessible, engaging for kids
CENTRAL ILLINOIS (WCIA) — A Central Illinois author is working to make science more accessible and easier to understand for kids. Seekers of Science, or SOS, is a STEM-based comic created by …
Kansas City health leaders announce new integrated theranostics research and treatment center
The center will unite diagnostics, molecular imaging, radiopharmaceutical production and targeted therapies under one coordinated platform.
‘Malcolm in the Middle: Life’s Still Unfair’ review: A lifeless revival
Save for Bryan Cranston, the "Malcolm in the Middle" revival is less an engaging revival than it is a tiresome dragging out of a television corpse.
Brand new musical 'Last Night on Rue Bayou' opens soon in New Orleans
Discover the vibrant music and captivating stories of "Last Night on Rue Bayou" and "Jagged Little Pill" in the upcoming productions in the area. Engaging performances and immersive experiences await!
Exclusive | Justice Department Opens Investigation Into NFL
Government officials have raised questions about whether the league is engaging in anticompetitive tactics that harm consumers.
Scientists just found a hidden “drain” inside the human brain
A hidden waste-removal pathway in the brain has finally been caught in action. Using cutting-edge MRI scans, researchers discovered that fluid flows along the middle meningeal artery in a slow, lymphatic-like pattern—very different from blood. This confirms the presence of a previously unknown drainage hub in humans. The finding could transform how scientists approach brain aging, injury, and diseases like Alzheimer’s.
Age-Friendly Kansas: Three-Year Action Plan
Age-Friendly Kansas Three-Year Action Plan: Promoting connection, reducing isolation and integrating healthy aging across sectors through practical strategies developed with state and national partners.
Your neighborhood could be aging you faster — and creating more 'zombie cells'
Secretary of State warns Montana businesses of deceptive mailing
Secretary of State Christi Jacobsen warned business owners Wednesday of a company engaging in “a new deceptive mailing."
Texas hemp industry leaders ask for temporary injunction against state
Restrictions set forth by DSHS include increased licensing fees, testing requirements and child-resistant packaging for hemp-derived THC products.
Access, AI and an aging population: ‘Business Report’ examines the state of Capital Region health care
Louisiana’s health care industry is contending with a convergence of pressures—an aging population, workforce shortages, access gaps and rapid technological change—and Business Report’s annual Trends in Health Care edition examines how Capital Region providers are responding. Here’s what you’ll find: AI is reshaping how care is delivered across the Capital Region. Area health care organizations […]
Fiesta Sports Foundation Names Nick Smith Board Chair, David Dorward Chair-Elect and Adds Two New Board Members
As Fiesta Sports Foundation continues to build on its legacy as one of Arizona's premier nonprofit organizations and a cornerstone of the college football community, it has named Nick Smith as Board Chair for the 2026-27 and 2027-28 seasons. In addition, the Foundation welcomed two accomplished executives to its Board of Directors, with the addition of LUV Car Wash Chief Financial Officer Jim Kebert and Levine Investments attorney Lisa Bullington. Starting a two-year term as Chair-Elect is Merrill Lynch Managing Director David Dorward, while Judy Bernas will serve as Chair Emeritus after completing her two-year term as Board Chair.
What Is Tmrw Longevity Powder? Here's what to know about the blue scoop
Tmrw Longevity Powder combines blue spirulina with a focused blend designed to support energy, clarity, digestion and healthy aging pathways.
Strengthening One Health through coordinated action on implementation, science, policy and financing - WOAH - World Organisation for Animal Health
Today, the Fourth Quadripartite Executive Annual Meeting will convene in Lyon, France, from 8-9 April 2026. The meeting will focus on preventing future health crises through more integrated systems for managing the health of animals, humans, plants and ecosystems. Preventing future health crises requires urgent, coordinated action that recognizes the deep interconnections between the health of […]
Strengthening One Health through coordinated action on implementation, science, policy and financing - WOAH - World Organisation for Animal Health
Today, the Fourth Quadripartite Executive Annual Meeting will convene in Lyon, France, from 8-9 April 2026. The meeting will focus on preventing future health crises through more integrated systems for managing the health of animals, humans, plants and ecosystems. Preventing future health crises requires urgent, coordinated action that recognizes the deep interconnections between the health of […]
Hologic hires former Baxter International chief as next CEO
José E. Almeida is taking over the top role at the Massachusetts-based breast imaging vendor, replacing retiring longtime leader Steve MacMillan.
South Carolina governor candidates tout infrastructure, growth at business forum
South Carolina’s crumbling roads, aging bridges and gaps in broadband access.
WhatsApp Gets New CarPlay App
Facebook-owned messaging app WhatsApp was today updated with expanded support for CarPlay. CarPlay users are able to more easily call and message their friends and family members in WhatsApp directly from the car interface. WhatsApp had CarPlay integration before, but with limited Siri-based functionality. The new app has a full native CarPlay interface with a list of recent chats and call history, along with a tab for favorite contacts.
Kansas governor warns of Legislature’s ‘political games,’ ‘micro-managing’ in eight-bill veto spree
Kansas Gov. Laura Kelly shot down legislation riddled with “bureaucratic red tape,” “political games” and “micro-managing” as part of her Monday veto spree.
As Job Stability Shifts, AI Platforms Aim to Remove the Barriers to Business Ownership
Skills that have made someone successful in a corporate career can certainly translate to work as an entrepreneur, but owning a business is a separate challenge entirely. Costly start-up fees, overhead, marketing, managing multiple software systems and expensive staff are some of the many reasons st
State Health Department workers face gas scares at aging office
State health workers in Albany say repeated gas scares at 875 Central Ave. have fueled calls for remote work.
Is your morning routine ruining your health?
Managing stress the moment your alarm goes off can make a massive difference in preventing long-term harm to your body.
The world’s “oldest octopus” was never an octopus
A famous “oldest octopus” fossil has been exposed as a case of mistaken identity. Advanced imaging revealed hidden teeth showing it was actually related to a nautilus, not an octopus. The confusion came from decay that altered its shape before fossilization. This discovery rewrites part of evolutionary history, pushing the true origin of octopuses much later in time.
Richard Lamondin pivots from congressional run to SD 38 challenge, drawing early party support
After months engaging voters in CD 27, Richard Lamondin is redirecting his campaign to a closely watched Miami-Dade Senate seat.
Vance makes time to visit Hungary to support Orbán amid Iran negotiations
The war with Iran is raging, gas prices continue to rise and spending battles persist on Capitol Hill. So why is the number two man in the White House flying to Budapest?
FTI Consulting Adds Three Leading Mining and Resources Business Improvement Experts
SYDNEY, April 06, 2026 (GLOBE NEWSWIRE) -- FTI Consulting, Inc. (NYSE: FCN) today announced the appointments of James Chapman, Steve Dyson and Franz Wentzel as Senior Managing Directors in its Australian Transformation practice, bringing their experience as former global heads of Big Four accounting firm mining practices to help clients realise their full value potential. The appointments of Mr. Chapman, Mr. Dyson and Mr. Wentzel continue the firm’s growth of its Transformation – Mining team, fo
New Research Brings Joint Repair Closer for Millions With Osteoarthritis
DURHAM, N.C. — Osteoarthritis affects more than 32 million Americans, making it one of the leading causes of chronic pain, disability, and loss of mobility in the United States.For many people, treatment options are limited to managing pain with medications or repeated injections, and in severe cases, replacing the joint entirely through surgery.
How Philips Personal Health is driving a circular economy through sustainable design
Discover how Philips Personal Health drives sustainable design and circular innovation using eco-friendly materials, refurbishment, packaging, and renewable energy.
Scientists may have found a way to keep your bones strong for life
Scientists have identified a little-known receptor, GPR133, as a powerful regulator of bone strength. By activating it with a newly discovered compound called AP503, they were able to boost bone density in mice and counteract osteoporosis-like damage. The finding opens the door to a new kind of treatment that could not only prevent bone loss but also rebuild weakened bones, offering fresh hope for millions affected by osteoporosis, especially aging populations.
Saturday Morning Science continues with 2 lectures in April
The science behind night vision imaging and green drug synthesis are the topics of the next two Saturday Morning Science lectures at the University of ...
Study Reveals the Single Cause of Cognitive Decline—and a Cure
Researchers pinpoint a lone protein that speeds up the dysfunction of an aging brain. Eliminating it, they claim, can reverse the damage.
How to ‘detox’ your body for free without juice, teas or flushes
Feel like your body needs a reset? What if we told you that you can ‘detox’ for free by leveraging your body’s natural waste removal systems. PolitiFact shares how to do some spring cleaning without paying for a “juice cleanse” or “detox diet.”
What is a biological age test? Experts talk benefits, risks of at-home testing
It’s important to understand what over-the-counter biological age test kits can — and can’t — do before buying them.
What Sea Creatures Reveal About How Fast People Age
By Carole Tanzer Miller HealthDay ReporterSUNDAY, April 5, 2026 (HealthDay News) — This is no ordinary fish story. Researchers who videotaped every moment in the lives of 81 African turquoise killfish gleaned intriguing insights into the aging process that may also apply to humans. Though killfish ...
Scientists found a protein that drives brain aging — and how to stop it
Scientists have uncovered a powerful new clue in the mystery of brain aging: a single protein called FTL1. In aging mice, higher levels of this protein weakened connections between brain cells and led to memory decline. But when researchers reduced FTL1, something remarkable happened — the brain began to recover, rebuilding lost connections and restoring memory performance.
Microsoft spent years pushing Copilot, but now it says don’t rely on it
Microsoft says Copilot is for “entertainment purposes only,” despite deep integration into Office and Windows, sparking criticism over mixed messaging.
Siemens Healthineers Diagnostics Review Puts Valuation And Business Mix In Focus
Siemens Healthineers (XTRA:SHL) is reviewing options for its Diagnostics business, including a possible sale. The review follows moves by Siemens AG to reduce its majority stake in Siemens Healthineers. Any decision could reshape the company’s business mix within the global healthcare diagnostics market. Siemens Healthineers operates across imaging, diagnostics and related healthcare technologies, giving it a broad role in hospital and lab workflows. A potential change in the Diagnostics...
Samsung Messages Is Officially Dead, Here's How to Switch
Samsung is officially handing messaging over to Google, and this is one of the clearest signs that One UI is more integrated with Google apps.
The FT’s AI optimism rests on shaky science
Last weekend, the Financial Times published an article about the broader social impacts of AI. Studying, managing, and mitigating the negative impacts of the technological transition is supremely important, and doing so requires both the electorate and policymakers to be informed by good, impartial science. Unfortunately, for anyone with even basic training in social science [...]Read More...
Bucks under investigation as Giannis speaks out, but the messaging doesn't add up
Giannis Antetokounmpo says he wants to play, but the situation and messaging around Milwaukee suggest a more complicated reality.