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Apple MacBook Pro 16 vs Microsoft Surface Laptop Ultra: Poll shows clear winner
With the launch of the newest Microsoft Surface Laptop Ultra, many people are comparing the laptop to the Apple MacBook Pro 16 with the M5 Pro. This comparison is quite apt, as both machines target the same audience. A poll run by Hardware Canucks has now revealed which laptop users prefer more.
Why we love to dress for the job we don’t have
Today, most of us probably work from behind a desk. Yet our obsession with clothes from a different kind of working life just won’t quit.
Scientists had coffee drinkers quit for two weeks. One result stood out
Quitting coffee led to an unexpected change in the body that went beyond caffeine.
Unique, quirky bookstores around the world worth a visit
In an increasing digital age, it appears that physical bookstores have become more than just places to buy books. They offer something that online shopping and e-books can’t quite replicate
Around the Big Ten: Grass is not quite green in Eugene
Around the Big Ten is back for another week, recapping all the important moments from the weekend.
The science, instinct and hard work behind Roosters’ success
Enter your email address to get each Tribune edition sent to your inbox Subscribe There’s a fair bit of unseen work that goes into winning an NRL premiership, dating back many months - just ask Simon Jones. The Sydney Roosters Head of Performance, who hails from Southland, has been in the thick of it. He played a lead role in guiding the 2026 champions through a marathon campaign that ended with a grand final win over the Newcastle Knights. The Roosters had to navigate the lengthy round-robin competition, including the pre-season, before playing through all four weeks of the finals series. It was a demanding stretch that tested the players and the staff responsible for keeping them on the field. “It is a hell of a beast, mate, to be honest,” Jones told The Roar Podcast. “There’s such a great group of staff there that know what they’re doing, and the boys are pretty professional.” Jones believed the Roosters managed the physical demands well, pointing to the health of the squad throughout the campaign and the decision to rest a significant portion of the playing group in the final round of the regular season. That call, made by head coach Trent Robinson and his coaching staff, proved valuable as the Roosters entered the finals with some energy in reserve. “We did finish the season physically where we needed to be, and we’d sort of had a pretty healthy squad all year,” Jones said. “To the team that do that, mate, mission accomplished, really.” It is the sort of work that often goes unnoticed when the spotlight falls on the players scoring tries and making match-winning plays, but Jones knows the cumulative effect of those decisions can be significant over a long season. After a win over Penrith had helped establish them as premiership favourites, losses to the Wests Tigers and Dolphins were followed by a defeat to the Panthers in the opening week of the finals. Rather than panic, the club refocused to position itself to challenge for the title. “The Tigers’ performance was probably the only one where you’re really quite disappointed because it’s hard to get to the top of the competition,” Jones told The Roar Podcast. “We had proof that we could; we knew what we needed to do. We just had to get back to that.” For Jones, the answer was not necessarily a radical change to the programme. It was about executing the basics consistently, both on the field and in preparation. “We just do the basics better than anybody else,” he said. “Whether that is actually the way you play the game or how you’re preparing, it’s just be really consistent, do the basics really, really well.” Like many professional sports teams, the Roosters are entrenched in sports science and performance data. The club has access to a range of information, including players’ sleep, GPS metrics and neuromuscular scores, helping staff assess how individuals are coping with training and competition. “We are very science-backed, and some people would say data-driven, but it’s people first,” he said. “The reason you collect all this data is to try and be the best for that person.” Jones said the club was also prepared to reconsider testing methods if they were not generating useful discussions or helping staff make better decisions. In an environment where technology is continually evolving, he believes experience and gut instinct remain important. “The data is no good unless you have conversations,” he said. “When you strip it right back, mate, trust the gut still and obviously, you know, just doing the basics really, really well.” The return of halfback Sam Walker provided a further example of the importance of individual determination and the work of the club’s medical team. Walker underwent ankle surgery late in the regular season, with his premiership campaign appearing in doubt. However, he was determined to return for the preliminary final. Jones said Walker was back at the training ground three days after surgery, walking freely enough to surprise those around him. While the surgeon’s work was crucial, Jones credited the halfback’s mindset as a major factor in the remarkable turnaround. “He was quite clear with Robbo after he got the surgery that he was going to make it back for the prelim finals,” Jones said. The Roosters’ performance programme also sits within a wider club culture that Jones believes is central to their success. Each season, players develop their own team mantra through a lengthy process facilitated by Robinson. It provides principles that the squad can connect to its actions on the field. Rather than simply carrying over the previous year’s wording after a successful campaign, the club repeats the process because the players’ ownership of it is what gives it meaning. “When it’s led, player-owned and player-led, mate, it’s really powerful,” Jones said. Get more from Logan Savory in the Substack app Available for iOS and Android Get the app Jones joined the Roosters in 2024 and said the environment had evolved as experienced players departed and younger members of the squad took on greater responsibility. Maintaining continuity in the club’s culture and preparation had helped the group navigate those changes. The premiership was a significant achievement for Jones, who acknowledged how difficult it was to win the NRL’s ultimate prize. However, he is already looking at how the performance programme can improve. “There’s still things within my role and things that I’d like to help improve at the club,” he said. For Jones and his team, the challenge now is to review the season, refine their systems and prepare for another campaign. The celebrations may have followed a memorable title win, but the work behind the scenes never really stops. The Southland Tribune is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe
Here's How Much A DVD Player Cost In 1997 Vs. 2026
Streaming content may be popular in 2026, but you can still buy a DVD player today, and for quite a bit less than the $749 you could have spent in 1997 dollars.
Two NC adults die after contracting West Nile virus, state health department says
There are currently no human vaccines or specific treatments available for West Nile virus and preventative measures are most effective.
Oregon's College Football Playoff Hopes Slashes After 'Fumbling' UCLA Game
The Oregon Ducks quite literally coughed up the game against UCLA and, along with it, coughed up their chances to make the College Football Playoff.
The Watch: U.S. Pharmacy Closures Are Deepening Inequities
Millions of Americans are left without access to prescription medications … Military and outdoor workers face the highest rates of death from heat … and more.
😱 Blimey! Scandinavian clash goes bonkers and breaks record
What the hell was going on in Sweden on Saturday afternoon? AIK Solna and IF Brommapojkarna served up a pretty wild shootout in the Allsvenskan.It had all started quite calmly, though – typically Sc...
Former Microsoft engineer left $200K job to build AI startup solo
Junead Khan left Microsoft after two years to pursue his AI startup. He explains why he quit his six-figure job without customers or VC funding.
Charleston restaurant outfitter said it was moving. Where’d it go?
North Charleston-based Berlin’s Restaurant Supply outfitted commercial kitchens for 4 decades. It quietly closed up shop in 2026, two years after it was acquired by a private equity buyer.
Global private equity fuels Indian healthcare’s push into smaller cities
Hospitals flush with foreign money are expanding rapidly and filling gaps in public infrastructure
Badgers swept in fifth straight loss to Nebraska
The Badgers fought quite hard, but fell short on Saturday.
Netflix star and musician boyfriend abruptly split after four years of dating
A Hollywood power couple has called it quits
How Kaiser Permanente Scales Up Social Health Initiatives
Q&A with KP’s Anand R. Shah, M.D., winner of the 2026 Alliance of Community Health Plans Bernard J. Tyson Health Equity Award
Mass. health officials confirm 13th human case of West nile virus in woman exposed in Middlesex County
Risk levels for the mosquito-born virus remain high in several communities, including Boston.
Ohio State alumnus David Jacobs’ interest in investing yields high return for students
David C. Jacobs began plotting his career path early in high school. It would begin at The Ohio State University with a bachelor’s degree in finance and marketing before continuing on Wall Street as a stockbroker. “It didn’t quite work out as planned,” he said. “But my time at Ohio State afforded me the opportunity to pivot quickly int...
Mac Mini (M6) Review: Still Great, But A Tougher Sell
Price hikes have come for the Mac mini, and while it's still a great miniature computer for those who want one, the value proposition isn't quite as strong.
Lib Dem MP quits frontbench job over Ed Davey's leadership
Deputy party leader Daisy Cooper says the vast majority of our MPs support Ed... and are furious at this distraction."
Owning Less Can Build More: When Small Businesses Should Raise Equity
When and how to evaluate using equity or debt financing
Design open science to be equitable, policymakers urged
Independent report for European Commission calls for “infradiversity” across infrastructures
First-of-its-kind health equity conference at UB seeks to bridge healthcare gap
The goal is to lay the groundwork that will bridge the gap in healthcare between the two cities.
Franchising Can Accelerate Growth But Is Your Business Ready?
Franchising offers entrepreneurs a way to expand without taking on debt or equity dilution. But that advantage comes with huge change in the founder’s role and control.
Hands-on — Xbox's brand new PC app offers BIG performance improvements
VIDEO: Today, I got a sneak peek at an early version of the Xbox PC app rebuilt experience, and for some it might look quite familiar.
The Wall Street Veteran Trying to Solve the Pentagon’s Missile Problem
In his first interview on the job, Deputy Secretary of Defense Steve Feinberg, a private-equity billionaire, defended his unusual approach.
The Public Health Cost of FDA’s Tobacco Review Delays
When avoidable delays in reviewing cigarette alternatives prolong smoking, they cost lives. Quitting reduces the risk of premature death, while continuing to smoke sustains exposure to the hazards responsible for smoking-related disease. Because cigarette smoking and secondhand smoke cause more than 480,000 deaths annually in the United States, the years-long delay documented in a September...
Big Ten has '18 strong members,' no expansion talks, commish says
Big Ten commissioner Tony Petitti said the conference has had "absolutely no discussions taking place around expansion, and there haven't been for quite some time."
'The Social Reckoning' is all clicks, but no results
It’s been made quite clear that “The Social Reckoning” is not a sequel to “The Social Network” but more of a “companion piece.”
‘Survivor 51’ star Rob Antonson insists ‘I’m not a quitter. I’m just not.’
‘Survivor 51’ player Rob Antonson looks back at his controversial exit and insists ‘I’m not a quitter. I’m just not. I’ve never quit anything in my life.’
Pro-ICE Film 'Pawn Shop' Crew Are Angry About Movie's MAGA Politics
A crew member who quit the pro-ICE film 'Pawn Shop' didn’t know its MAGA politics when hired, raising questions about what productions disclose.
Watchdog seeks tighter oversight of private equity-backed insurers
European insurance regulators have urged EU member states to scrutinize private equity-backed insurers more closely, even before they are authorized to operate, The Royal Gazette reported.
SEVEN FEATHERS HEALTH: St. Pierre aims to help those in need and inspire the next generation
The drive for Dr. Dakota St. Pierre’s career is quite simple, to serve people in need, transform a health care system he views flawed and inspire young people who are
Direct Relief Invests in Community Birth Centers to Improve Maternal and Newborn Health
Direct Relief is expanding its support for maternal and newborn health in the United States through new investments in nonprofit community birth centers providing care in medically underserved comm…
Open science is compatible with research security, says Canada’s chief science advisor
Open science is “not incompatible” with research security and science leaders and policymakers should “demystify” the false dichotomy between the two, according to Mona Nemer, Canada’s chief science advisor. More than a decade ago, EU policymakers were promoting open science, open innovation and open collaboration across the world. It was a political movement that aimed to make scientific research, data, software, publications and methodologies transparent, accessible and reusable for everyone.But that rhetoric has changed over the past few years. After Russia invaded Ukraine in 2022 and Donald Trump came back to power in 2025, international partnerships have become more pragmatic. Countries are trying to implement protectionist policies and governments are increasingly worried about technology espionage. According to Nemer, science can remain open if the sector can come up with improved security protocols that would protect research data from undue manipulation by foreign actors. “If anybody can fiddle with the with the data, then [open science] is actually quite dangerous and quite useless,” she told Science|Business. Universities and research institutions are increasingly vulnerable to attempted espionage and other types of foreign interference. In September, the UK’s domestic counter-intelligence service MI5 issued a security warning against collaborations with the China General Technology Research Institute. And earlier this year, Germany’s Helmholtz Center for Information Security was criticised by federal research minister Dorothee Bär, who told a parliamentary hearing that “existing rules and systems” at the institute “were not suitable” for preventing leaks to China. According to Nemer, universities and research institutions should perhaps follow the example of the private sector, as companies have been able to safeguard their research while still publishing results. “I think that there is a level of research security hygiene that researchers and institutions need to just adopt,” she said. “You don't have to tell Sanofi or IBM how to safeguard their research, which they end up publishing anyway.”While certain areas of research will not be open for collaboration with certain partners, in other areas cooperation is necessary even with researchers based in adversarial countries. “I stress this because politics change,” she said. “Science and politics don't make for good fellows, and whether we like it or not, politics will influence certain things.”Researchers will play an important role in “protecting the integrity of science,” said Nemer. “I think that it's time that there's a commitment to a certain scientific compact, so that citizens don't think that science is actually an open door for espionage and for anti-nationalism.”New partnershipsNemer spoke with Science|Business on the margins of the Hamburg Science Summit on September 17, the day when Canadian Prime Minister Mark Carney called for increased cooperation with the EU, including in science and technology. Canada is looking to strengthen ties with partners in other corners of the world, after the Trump administration threatened to put tariffs on Canadian goods and services and even openly suggested Canada could become the 51st state. In parallel, the US government has indicated it wants to retreat from international science projects, including US collaboration with Europe’s CERN particle accelerator and other big science labs.Related articlesThe stats we need to better understand R&DCanada looks to deepen research and education links with the EUCan researchers trust that AI models won’t leak their ideas?Nemer said the US is still a science “powerhouse,” but Canada and Europe will have to work closely together on global challenges. “It’s important for both [sides], but I think it's also important for the rest of the world, because the cut in funding for development, in health, in regions like Africa and other places, have dramatic effects.” The Trump administration is also planning a review of the Nelson memo, a Biden-era document that mandated that results of federally funded research would be openly available. With that idea being called into question, Nemer said it could be “very disruptive” to scientific collaborations and could jeopardise research on climate change, the Arctic and global health. “When your collaborator suddenly tells you I'm not going to share the data with you as a researcher, if this happens, I think it's very worrisome,” she said. “I'm certainly hoping that a lot of the Canadian institutions, funders, researchers, have started looking at joining forces on databases and using more European research infrastructures,” Nemer added.
Morikawa says LIV players face 'business decision' after Rahm exit
Double major winner Collin Morikawa said Thursday that LIV Golf players have to make "a business decision" about their futures, after Jon Rahm's lawyer said the Spanish star was quitting the breakaway…
Open Science and Equity: Does openness alone lead to fairness?
Open Science improves sharing and reuse of knowledge, increases transparency, and encourages public participation in the research process. While this approach has gained widespread support from researchers and policymakers, the new report, “Equity in Open Science: Case studies of Open Science infrastructures and Open Peer Review”, shows that openness alone does not automatically lead to […]
'Survivor 51' recap. One player quits and another abandons his tribe
Warning: The following contains major spoilers for the Wednesday, Oct. 7, episode of "Survivor 51." "Survivor" blindsides are in full swing during the open era.
‘Survivor 51’ recap: A player quits the game due to a ‘tiny cut’
A ‘Survivor 51’ player quits the game due to a ‘tiny cut’ that is smaller than every cut on every contestant to ever play the game. Read EW’s recap.
Who Won August and September: Original Films or Franchises?
(Welcome to the Entertainment Strategy Guy, a newsletter on the entertainment industry and business strategy. I write a weekly Streaming Ratings Report and a bi-weekly strategy column, along with occasional deep dives into other topics, like today’s article. Please subscribe.) I just heard someone say that if you’re reading a pundit or data analyst, and they don’t tell you that they got anything wrong, they’re not a pundit but an “influencer”. I agree with that. You have to tell your audience when you get things wrong, or they won’t (or shouldn’t) trust you as much. Today, we’ve got another edition of “What I Got Right, What I Got Wrong”. In general, I’m patting myself on the back (and patting very hard) about a few things like IP at the box office, LIV golf, horror films, crowdfunding movies, superheroes, and old people going to the theaters. That said, I also made a couple of data mistakes on the streaming bubble popping and HBO’s datecdotes, so I’m not perfect. But first, I need your feedback... Subscribe Follow-Ups: What Should We Call Mid-Budget Movies Which Aren’t Cinematic Enough for Theaters But Are Too Expensive to Make Money on Streaming? After I asked for feedback on what we should call straight-to-streaming films that are too big to pencil out on streaming but not really big enough to resonate in theaters, I got some great suggestions from you all, including... “Moldilocks” from John Aboud “Little Big Indie” from Travis Frick1 “Midflicks” from Jonathan Funke. “Extra-Medium” from Jona Nwuke. (Read the explanation in the footnote.) Between these and Brandon Katz—who suggested “Bermuda Budget Triangle”, “The Platform Gap” and “The Distribution Deadzone”—we’ve got some excellent suggestions. And they’re better than my suggestion, the “Streaming Budget Dead Zone”, so let’s take a poll! The winning entry becomes the new term. Loading... RIGHT: LIV Golf is Fully Bankrupt…Is Anyone Else Next? A few years ago, I was always a bit perplexed at all the articles I’d read praising LIV Golf and their strategy to disrupt the PGA. LIV Golf, a brand new professional golf league, offered PGA stars ten times what they made on the PGA Tour to join their new league. And folks praised this strategy for its initial “success” in that a lot of big names did indeed leave the PGA. Yeah, of course the players came over. LIV Golf paid them so, so, so much more! But LIV Golf hadn’t discovered a way to increase potential revenue. So think about this in basic business terms… They paid much more in costs… …but had no real way to increase revenue. That’s not a strategy! That’s deficit financing. It won’t work unless you bankrupt the competition (and then turn around and pay those same golfers much, much less). It’s not a sustainable strategy and only lasts as long as the company/person/nation backing it decides they’re cool with losing money. For LIV Golf, that meant Middle East oil wealth, in particular Saudi Arabian money. Clearly, the current Iran War has hurt Middle East finances, so they need to trim their more exorbitant spending. And LIV Golf was part of that trimming. This should be a major warning for others. TGL’s parent company, TMRW Sports, just got a $1 billion valuation, despite TGL’s (the indoor golf league) horrible TV viewership of less than half a million viewers per match. Unrivaled, the women’s basketball league, just secured a $650 valuation, despite its horrible TV viewership and a new rival (Project B) entering the scene next year. To relate this to streaming, Hollywood should ask which streamers may have wealthy patrons funding their losses. (Let’s be clear: Google, Amazon and Apple.) Could those patrons lose their appetite? For Amazon, probably not. But Apple has a new boss, so maybe! WRONG: My Analysis of the Streaming Bubble Was Missing a Week I’m going to be congratulating myself a lot today, but I make mistakes too, like this data goof. When I last compiled the data on the decline in TV shows, I was missing one week at the end of June. If you look at the first image, you can see that one week was mislabelled as “July”. Mainly, this image got updated to show a 27% decline, not 29%: This change doesn’t really impact the overall analysis, but it is two percent better. By the way, through the third quarter, the decline increased and it’s now a 30% decrease since 2022. (I’ll write/visualize this in an upcoming article.) But I want you to trust me and my data. Especially these days, when many people are using LLMs that I know are inserting faulty data into their charts, I want to keep earning my audience’s faith. So that’s the accurate data. RIGHT: IP Remains Very, Very Popular In July, I wrote a giant (and I mean giant) article on Backrooms, Obsession, and the box office, going over what we know, what we don’t know about what works in theaters, looking at YouTubers, IP, the horror genre, comic book movies, and a whole lot more. The month of August really tested a lot of my theses and, being honest, mostly supported my arguments. Let’s start with IP. Looking at 8-Aug (the weekend after Spider-Man: Brand New Day came out) to 18-Sep (the weekend that Resident Evil came out, which I think provides a nice bookend to this time period), there were seven films based on pre-existing IP: Resident Evil (2026) ($126 million) Practical Magic 2 ($65 million) _Insidious: Out of the Furthe_r ($65 million) Coyote Vs. Acme ($59 million) Paw Patrol: The Dino Movie ($53 million) Tony ($15 million) Super Troopers 3 ($7 million) Compare those to the notable original films from the past month—I actually could have included more movies, but here are just thirteen, bringing us to an even twenty films—including.... The End of Oak Street ($54 million) Buddy ($26 million) Mutiny ($15 million) By Any Means ($15 million) The Dog Stars ($14 million) Runner ($14 million) One Night Only ($11 million) Hope ($8 million) Spa Weekend ($7 million) The Uprising ($6 million) Teenage Sex and Death at Camp Miasma ($6 million) Onslaught ($3 million) Eli Roth’s Ice Cream Man ($2.8 million) Here’s that in chart form: Five of the top six films in this time period were all based on IP. I made a big chart of films that grossed over $200 million at the box office before Spider-Man: Brand New Day and The Odyssey hit theaters. Let’s update that chart! By the way, if you want to see how I categorized each film—so another bar chart—here it is: I know that many of my fellow critics/pundits/analysts dislike films based on IP and how Hollywood is making so many of them. And I’m sympathetic to this point of view. As I’ve written many, many times before, you need a balance between existing franchises, new IP, and original films. And Hollywood clearly needs to make more films like Resident Evil (a well-made film from a visionary director) and fewer Practical Magic 2’s (which didn’t get critical or customer buzz). But at some point, critics and pundits need to contend with what audiences are telling them: Movie-goers aren’t showing up to original films. Audiences are speaking with their dollars, telling you they want more IP and franchises. You can try to convince studio heads to make fewer IP-based films and franchises, but the data and numbers aren’t there. Instead, critics need to work harder to convince audiences to show up for original films. Aim your ire/concern at the average person, not studio heads.2 Because they’re just making the films that audiences are telling them to make. WRONG: Original Horror Films Didn’t Break Out I’ll be honest, even though I wrote an article casting some skepticism on the horror genre in July, if you asked me to make a prediction, I would have predicted that, in August, a new, original horror film would have blown up. No, seriously, I just assumed that Obsession and Backrooms presaged a change in audience behavior. But none of the buzzy new original horror films from August—Teenage Sex and Death at Camp Miasma, Onslaught (not an action film in spite of the ads), The End of Oak Street, Eli Roth’s Ice Cream Man, or _Buddy—_broke out. To be clear, exactly one of those films (Buddy) had good “ROI”, but again—I try to be specific in my language—none were “popular” in any broad sense of the word. None of them will be “saving” movies theaters like Backrooms or _Obsession_helped save the summer. The new Insidious film and Resident Evil, both based on IP, were far and away the biggest horror films since July. (We’ll see if this changes in October/Halloween season.) RIGHT: Stay Skeptical about Crowdfunding... I’ve long been skeptical about crowd-investing platforms as one of Hollywood’s saviors, mainly because there’s so much hype/buzz. People need to stay more skeptical about more things, explaining both the potential upside but also the downsides. In particular, the media often hypes crowdfunding at the start and never checks in on the actual results after they’ve come in later. And August gave us our first update! _Ice Cream Man—_directed by Eli Roth—grossed $6 million off of a $5.5 million budget. This is a production of The Horror Section, which was one of the first “crowd investing” studios with 2,400 investors, which means that 2,400 investors probably lost money. They certainly aren’t getting as great of returns as if they had just invested their dollars in the stock market. Hopefully Stiletto (Tagline: “Someone’s Going to Make it Rain Blood!”) does better next month. WRONG: Another Data Goof Here’s another data error. When the first episode of House of the Dragon came out, HBO put out that it had 21.5 million viewers in the first three days, and I read that to mean in the US…but no, it was global. So my US-only datecdotes charts shouldn’t have included it. We never got US-only numbers for the first episode, but for the final episode, HBO put out that it had 11 million US viewers. (And that global dropped to 21 million viewers.) Here’s the updated chart (which I’ve since used in the Streaming Ratings Report): Still, this show is absolutely huge. RIGHT: Superhero Films Remain Very, Very Popular After Supergirl flopped, I read a few takes that “comic book movies are going the way of the Western”. Post-Spider-Man: Brand New Day, that take didn’t age well. To be fair, I have a very nuanced take on the superhero genre right now; it’s down right now, for a lot of reasons. But it’s not “dead”. Maybe _Spider-_Man is just a really popular character? I saw that take, and it’s a fair counter-argument. (But pundits arguing that superhero movies were dead should have mentioned this $1.5 billion counter-argument…) But is it just Spider-Man? The next Avengers film already has $50 million in pre-sales (and I was skeptical that that film would do well) and the Avengers: End Game re-release topped the box office two weekends ago (over three original films). And I wouldn’t bet against Batman or Superman. So maybe it’s just Spider-Man, Batman, Superman and the Avengers. Oh, and Deadpool, of course. And Black Panther. And Wolverine. And probably the X-Men. Plus a well-made Wonder Woman or the Hulk film could break out. But that’s it! It’s just those ten characters/teams. Oh, what’s that? Lanterns is also doing well on HBO? (See previous section…) To be fair, I’m actually pretty sympathetic to the argument that more popular characters—like Spider-Man and Batman—anchor more popular films. In fact, I made that exact argument three years ago when I first wrote about the “Marvel-cession”. In many ways, you can blame The Guardians of the Galaxy for fooling Marvel Studios (and the rest of us) into believing that any character could pop. It turns out, the list of iconic characters is probably smaller than most people think. But it’s probably too early to say that superhero films and comic book movies are dead unless “death” means a slight decline over a longtime. RIGHT: Who Killed Theaters? Old People I get frustrated whenever I see headlines or analysis about how young people are “returning” to theaters. As I’ve detailed(for years), young people have always powered the US box office, despite narratives about “kids these days” and their “phones”. Really, what’s changed post-2020/pandemic is that old people aren’t going to the movies nearly as much. This summer, I saw a movie (from an older director) in a theater near a retirement community, and multiple older people at the theater were talking about how this was their first time seeing a movie in years. I dislike personal anecdotes, so YouGov can fill in the data, best summarized by this headline: “Who killed movie theaters? Not the youths”. According to them, 64% of people aged 18-29 have seen a movie in the last year, but only 30% of 65-and-older. 20% of 18-29 have seen a movie in theaters in the last week and 42% in the last month. Here’s the polling data: Most concerning? Many Americans (17%) think theaters are a worse or much worse experience than watching films at home. Slight WRONG: Hadestown Opens Big A live theater capture of the Broadway musical, Hadestown, made $20 million at the US box office, which begs the question: was I wrong to be skeptical about musicals a few years ago? Yes and no. On the one hand, $20 million is a far cry from being “popular”, so yeah, the genre isn’t that popular overall and Hadestown is one of the more popular musicals from recent years (i.e. the “Taylor Swift Data Fallacy” in action). On the other, I doubt filming this cost all that much, and I don’t think that they spent much on marketing, so this is a good source of ancillary revenue. Smaller Updates WRONG: As I mentioned in a Streaming Ratings Report, I underestimated the budget for Enola Holmes 3. It probably cost more like $50 million, if not more. But... I’m not sure that it really matters? At sub-10 million hours, prices have to come down to make this work. WRONG: Netflix is giving Ink a 27-day in theaters! To quote the kids/YouTubers these days, let’s go! Now I might actually have a chance to see Danny Boyle’s latest in theaters. I’d complained about this in a “Coming Soon” section, but I was heartened to read that Netflix is giving multiple films longer theatrical windows this year. RIGHT: Netflix is sending 4-5 films per year to theaters. Netflix is slowly but surely sending more and more films to theaters, as I cautiously predicted earlier this year. For now, it’s just three big films and a number of awards contenders, but still, this is great news. And they’ll be releasing box office grosses! Just this week, Ted Sarandos confirmed that KPop Demon Hunters 2 will come to theaters (and my guess is it performs in the box office top ten at a minimum). WRONG: Angel has 3 million subscribers! How do I know this? Well, they told Deadline, who reported it. I marked this as “wrong”, since they’ve doubled their subscribers in one year but, you know, they don’t really have a hit film to speak of and they’re still losing money. WRONG: Furious was only renewed for one more season. I accidentally wrote “two more seasons” in my latest “Renewals, Cancellations, Un-Orders and Removals Update”. RIGHT: House of David is ending with its third season. In July, Prime Video renewed House of David for a third season, as I just wrote in my latest “Renewals and Cancellations” report. Well, now it’s ending after that third season. Why? As I’ve been writing, its viewership wasn’t great. I got feedback that this show didn’t cost very much, but it cost enough that its limited viewership didn’t save it. WRONG: Adults was a Hulu original! So I missed Adults when it first came out last year; I saw that it aired on FX and just assumed that it was a linear-first program. Turns out, it aired three episodes on FX, but binge-released the rest of its episodes the next day on Hulu. Huh. So I should have covered it last year! But I just wrote about it. 1 “When I was a kid in the 90s, if you wore a t-shirt to school that wasn’t too big and also wasn’t too small, but somehow didn’t quite fit, we’d say you were wearing an “extra-medium” shirt.” 2 As always, a huge exception is Disney, which barely makes anything original anymore.
Virginia’s two biggest craft beer brewers to merge
Richmond's Hardywood Park Craft Brewery has purchased Starr Hill Brewery, based in Crozet, in an all-equity acquisition. Richmond's Hardywood Park Craft Brewery has purchased Starr Hill Brewery, based in Crozet, in an all-equity acquisition.
CCDPH Launches “Spread Facts, Not Flu & COVID” Campaign Ahead of Respiratory Virus Season - Cook County Department of Public Health
Today, Cook County Department of Public Health launched Building Healthier Communities 2030, suburban Cook County’s Community Health Improvement Plan. The plan was announced together with Cook County Board President Toni Preckwinkle, Cook County Department of Public Health, community organizations, healthcare providers and cross-sector partners. Building Healthier Communities 2030 serves as both a collective vision and a practical roadmap that will guide public health efforts across suburban Cook County through 2030.The plan aligns with President Preckwinkle's Policy Roadmap and reflects a shared commitment to advancing health equity through coordinated, community-informed action.
B.P. Marsh takes 30% of marine underwriting startup
British private equity firm B.P. Marsh and Partners plc has acquired a 30% stake in newly formed London Market underwriting agency Dauntless U/W Ltd., Reinsurance News reported.
Formula 1: Max Verstappen says sport 'less stressful' without Christian Horner, speaks on whether he would drive for Ferrari and his new contract
Max Verstappen on F1 post Christian Horner: It is not as spicy but I quite like how things are going with everyones behaviour, lets put it like that; Verstappen says it is not my concern if Horner returns to sport; watch Singapore Grand Prix weekend live on Sky Sports F1 from Friday
Iowa football plummets in latest USA TODAY Sports 1-138 Re-Rank
Iowa football dropped quite a ways in the newest USA TODAY Sports 1-138 Re-Rank following its loss to Ohio State.
Latinx Voces Expands Grassroots Health Equity Across the Valley
A podcast with Dr. Paulina Sosa Quintanilla, founder and CEO of Latinx Voces.
Why advanced diagnostics are essential for health equity in Asia
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Latham & Watkins Advises Spectrum Equity on Growth Investment in Symmetric Health Solutions
Multidisciplinary team represents the growth equity firm in investment in the healthcare supply chain intelligence provider.
Disney Believe Entertainment Guide: Shows, Characters & More.
What entertainment will be on the Disney Believe? We’re tracking all of the stage shows, character appearances, deck parties, kids clubs, and other entertainment coming to Disney Cruise Line’s newest ship. Disney Cruise Line’s newest ship, the Disney Believe, is preparing to set sail in late 2027. And while there’s still quite a bit Disney ...
Florida Department of Health warns of mosquito-borne illnesses in tested Manatee County chickens
DOH- Manatee and the Manatee County Mosquito Control District are coordinating surveillance and prevention efforts by source reduction.
Shohei Ohtani’s Humble Dodgers Reaction Goes Against Superstar Stereotype
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Deals: here are the best tablet and smartwatch deals from Amazon's Prime Big Deal Days
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Local Farms and Food Businesses Receive Nearly $500,000 in Grants to Help Make Metro Chicago Food System More Equitable - Cook County Department of Public Health
Today, Cook County Department of Public Health launched Building Healthier Communities 2030, suburban Cook County’s Community Health Improvement Plan. The plan was announced together with Cook County Board President Toni Preckwinkle, Cook County Department of Public Health, community organizations, healthcare providers and cross-sector partners. Building Healthier Communities 2030 serves as both a collective vision and a practical roadmap that will guide public health efforts across suburban Cook County through 2030.The plan aligns with President Preckwinkle's Policy Roadmap and reflects a shared commitment to advancing health equity through coordinated, community-informed action.
Local Farms and Food Businesses Receive Nearly $500,000 in Grants to Help Make Metro Chicago Food System More Equitable - Cook County Department of Public Health
Today, Cook County Department of Public Health launched Building Healthier Communities 2030, suburban Cook County’s Community Health Improvement Plan. The plan was announced together with Cook County Board President Toni Preckwinkle, Cook County Department of Public Health, community organizations, healthcare providers and cross-sector partners. Building Healthier Communities 2030 serves as both a collective vision and a practical roadmap that will guide public health efforts across suburban Cook County through 2030.The plan aligns with President Preckwinkle's Policy Roadmap and reflects a shared commitment to advancing health equity through coordinated, community-informed action.
Seiko’s New Affordable Chronograph Takes the “Panda” Moniker to Its Logical Conclusion
You've never seen a "panda" dial watch quite like this before.
Claude launches Google Docs, Sheets, and Slides integration with sidebar and more
If Gemini isn’t quite your cup of tea, Anthropic’s Claude now supports sidebar integration with Google Docs, Sheets, and Slides....
CD&R, McKesson acquiring infusion therapy provider Option Care Health for $5.8B
Option Care Health, a provider of infusion therapy services, is being acquired by private equity firm CD&R and healthcare conglomerate McKesson in a deal valued at $5.8 billion, the companies a | Option Care Health, the country's largest independent provider of at-home and alternate site infusion services, would go private in the deal, which is expected to close in the first half of 2027.
Oak Park approves five-year public health plan focusing on equity
The new Illinois Project for Local Needs Assessment, or IPLAN, from the public health department aims to help fix health inequities in Oak Park.
Special Olympics Switzerland Re-Launches Health Program with First Annual Health Congress
The inaugural conference called for action on health equity for people with intellectual and developmental disabilities.
Block Club Chicago’s Free South Side Health & Wellness Fest Is Coming to Chatham
Join Block Club and community partners on Nov. 7 for activities and resources to help address health equity gaps. Join a fun run with Joabe Barbosa, get a free meal and more.
McKesson, CD&R to take infusion therapy provider Option Care private in $5.8 billion deal
Drug distributor McKesson and private equity firm Clayton Dubilier & Rice on Tuesday agreed to take infusion therapy provider Option Care Health private in a deal worth about $5.8 billion including debt.
Countries race to provide oral health care for all in 100-Day Sprint across Asia
Twenty Asian countries and areas across the WHO Western Pacific and South-East Asia regions vowed to strengthen essential oral health benefits as part of a “100-Day Sprint” initiative, during the 16th Asian Chief Dental Officers Meeting held from 27 to 29 September in Kota Kinabalu, Malaysia. The meeting marked the midpoint of the 100-day sprint bolstering support for countries to develop essential oral health benefit packages that can be integrated into national universal health coverage plans. Convened by the two WHO regional offices and the Malaysian Ministry of Health as the Secretariat, the meeting brought together national oral health leaders from 20 Asian countries, staff from all levels of WHO, WHO collaborating centres and other development partners. Participating countries and areas included: Bangladesh, Bhutan, Brunei Darussalam, Cambodia, China, Hong Kong (SAR) China, India, Indonesia, Japan, Lao People’s Democratic Republic, Malaysia, Maldives, Mongolia, Nepal, the Philippines, Singapore, Sri Lanka, Thailand, Timor-Leste and Viet Nam. Participants reviewed progress and refined proposals using the WHO Service Package Delivery and Implementation (SPDI) Platform. Countries conducted bottleneck analyses across four key areas: service delivery, workforce, access to essential medicines and health products, and health financing. They identified practical actions to address implementation challenges and refined proposed revisions to their national oral health benefit packages. “There is no health without oral health. Through the 100-Day Sprint, countries are advancing the implementation of the Western Pacific regional implementation plan on oral health and strengthening progress towards universal health coverage,” noted WHO Regional Director for the Western Pacific Dr Saia Ma'u Piukala. Participants identified bottlenecks and proposed workable solutions to strengthen access to essential oral health care through primary health care, sharing experiences and discussing how best to translate policy commitments into feasible and sustainable action at the country level. Malaysian Minister of Health Datuk Seri Dr Dzulkefly Ahmad highlighted the importance of prevention and primary health-care approaches to improve oral health: “Oral diseases can have lifelong consequences, yet many are preventable. By integrating essential oral health care into primary health care and promoting prevention in schools and communities, we can improve oral health across the life course.”The WHO team led by Dr Huong Tran, Director of the Division of Health Promotion, Disease Prevention and Control of the WHO Western Pacific Region and national oral health leads from over 20 Asian countries visited the SK Pekan Putatan School, Sabah for school oral health programme including flouride mouth rinsing. © WHO / V. ChaudharyDr Huong Tran, Director of the Division of Health Promotion, Disease Prevention and Control for the WHO Western Pacific Region, emphasized key collaborative roles WHO can play. “Oral diseases are the most common noncommunicable diseases, yet many can be prevented and treated through essential oral health services delivered at the primary health-care level,” she said. “By sharing experiences and using WHO tools such as the SPDI Platform, countries are accelerating progress towards universal health coverage for oral health.” “Integrating oral health into broader health services is essential for reducing inequities, expanding access and recognizing oral health as an integral component of overall health and well-being. The 100-Day Sprint provides an important opportunity to translate this commitment into practical action and ensure that quality oral health services reach all people, especially those most in need,” said Dr Suman Rijal, Director of the WHO South-East Asia regional Department of Healthier Populations and Noncommunicable Diseases. As host of the meeting, Malaysia showcased ongoing efforts to strengthen oral health care through primary health care and prevention-focused approaches, while providing a platform for countries across the two WHO regions to exchange experiences and accelerate progress towards universal health coverage for oral health. “WHO is encouraged by Malaysia's leadership in addressing the burden of oral diseases and advancing universal health coverage for oral health through practical, country-led action,” said Dr Rabi Abeyasinghe, WHO Representative to Malaysia, Brunei Darussalam and Singapore. Countries will continue to refine and figure costs for national oral health benefits during the remaining sessions of the 100 days. These efforts support implementation of the WHO Global strategy and action plan on oral health 2023–2030, while also helping to expand access to essential oral health services through stronger and more equitable health systems across the WHO Western Pacific and South-East Asia regions.______________For more information, or to arrange media interviews, contact: WHO Regional Office for the Western Pacific: wprocom@who.int WHO Regional Office for South-East Asia: SEMediaRelations@who.int
Scamacca ‘very happy’ with first Italy goal in three years
Gianluca Scamacca is ‘very happy’ to have scored his first Italy goal in three years, paving the way for the 3-1 win over Turkiye in the Nations League.The Azzurri had quite a sluggish start again...
University of New Haven Researchers Advance Health Equity and Health-S
Research focused on health equity and health-system transformation has grown from a 2023 faculty-student project into a broad, collaborative body of scholarship involving students, faculty, health sys
The upcoming D&D interpretation of World of Warcraft sounds great, but don't expect it to work like the MMO does
World of Warcraft is being given the Dungeons & Dragons treatment in a massive new book. But D&D: WoW works quite differently to the MMO.
Hamilton County Public Health reports first human West Nile virus case
Officials said the evidence supports that the person, who lives in the Symmes Township area, was likely bitten by a local mosquito
Hamilton County Public Health reports first human West Nile virus case
Officials said the evidence supports that the person, who lives in the Symmes Township area, was likely bitten by a local mosquito
Science in French? Bien sûr!
As English dominates the publication landscape, support for French-language research is a strategic investment in the quality, equity and the future of knowledge.
Fantastical’s long-awaited Android debut begins today on Googlebook
After 15 years, Fantastical's acclaimed calendar app is coming to Android, but it's not quite ready for every device just yet.
Neighborhood Intelligence Provides Business Update and Announces $45.5 Million Equity Financing with Participation from Management and a Single Institutional Investor
NASHVILLE, Tenn., October 05, 2026--Neighborhood Intelligence (NASDAQ: NXH) ("Neighborhood" or the "Company") today announced that it has entered into a definitive agreement for the purchase and sale of an aggregate of 16,485,508 shares of its common stock (or pre-funded warrants in lieu thereof) at a purchase price of $2.76 per share (or pre-funded warrant in lieu thereof) in a registered direct offering. In addition, the Company will issue warrants to purchase up to 16,123,189 shares of common
Yale School of Medicine On the Science of Childhood Anxiety, Say, Anxiety Disorders Are the Most Common Mental Health Challenges In Youth
Credit: Matt Bradbury October 5, 2026 - By Isabella Backman - Anxiety disorders are the most common mental health challenges in youth. Left untreated, they can disrupt the lives of both children and their families. The good news is that with intervention, most children will overcome these conditions. Across Yale School of Medicine, scientists are working to understand anxiety at every level, from common anxious behaviors to molecular biomarkers in the brain. They are using their findings to develop and disseminate new evidence-based treatments for childhood anxiety. Today, the go-to treatment for childhood anxiety disorders is cognitive behavioral therapy (CBT). This is a form of psychotherapy that teaches children skills for confronting anxious thoughts and helps them practice managing situations that cause anxiety. While it is the gold-standard treatment backed by considerable scientific evidence, up to 50% of children will not see sufficient benefit from CBT alone. Wendy Silverman, PhD, Alfred A. Messer Professor in the Child Study Center, co-directs the Anxiety and Mood Disorders Program alongside Eli Lebowitz, PhD, associate professor in the Child Study Center. One of their main interests is learning how to improve outcomes beyond CBT. “We’re developing cutting-edge, research-based knowledge that can reduce the suffering that anxiety causes children and their families,” says Silverman. Changing parent behavior YSM experts are investigating how to improve CBT outcomes for children by involving the parents. Silverman’s research has uncovered two main components of parent intervention that improve childhood anxiety: not enabling children to completely avoid the things that make them anxious and taking steps to enhance their autonomy. Parents may unintentionally reinforce their child’s anxiety by allowing them to avoid what makes them anxious. They also may unintentionally limit the children’s sense of autonomy by being overly intrusive. “One of the things that we take pride in is that we’ve focused on trying to understand what parents need to do, and to test our ideas and see if changing the parents’ behaviors is enhancing the effects of CBT,” Silverman says. “Our findings thus far suggest that they do." As much as CBT can be helpful, it can also be challenging to get one’s child to do the necessary steps for CBT to work. This is one important reason why Lebowitz created a novel intervention program for parents named Supportive Parenting for Anxious Childhood Emotions (SPACE). Existing intervention programs often teach parents to act as therapists for their child, such as training them on how to practice breathing exercises. “It makes sense, but this doesn’t work very well in practice,” says Lebowitz. “And part of the reason, I think, is that it’s not easy to get your kid to do things, especially if they’re not excited about doing it.” SPACE is unique because it focuses entirely on parent involvement and changing parental behavior—children are not involved in the sessions. For example, parents learn how to use supportive messages that convey confidence that their child can tolerate and manage distress. “It might sound like a parent saying to a child, ‘I get that this is really hard for you, but I know that you can handle it,’” Lebowitz says. The program also works with parents to identify the ways in which they are accommodating anxious behaviors. “We’ll pick one thing that parents are doing that is an accommodation and help them make a detailed plan for how they’re going to change that,” Lebowitz explains. Treating Anxiety in Children and Adolescents Much of the existing research on SPACE has focused on parents of children under age 14. Ongoing studies are now exploring its use with parents of older teens. “Both anxiety and accommodation can interfere with normative developmental shifts during the teen years, including increased autonomy and individuation from parents,” says Rebecca Etkin, PhD, associate research scientist in the Child Study Center. “In this sense, SPACE may be particularly well-suited for anxious teens and their parents. We want to see whether it is effective during this distinct developmental window.” Unfortunately, many families in need of CBT face barriers, including limited availability of services and geographic constraints. One way to improve access is digital interventions. Silverman and her team are developing an evidence-based digitized intervention program for parents that they can access directly from their computer or smart phone. “The work we’re doing will be one of the very few parent interventions that is digitized and importantly tested for effectiveness,” she says. Creating interventions for anxiety-related challenges Silverman and Lebowitz recently received a generous gift to develop and test other interventions that help parents reduce other child anxiety-related behavioral and emotional difficulties, such as restrictive eating and unexplained somatic symptoms. One of these projects in particular focuses on understanding the risks of social media and its potential benefits, including offering a sense of connection. “A lot of research has focused on the idea that social media is harmful and the less of it the better,” says Lebowitz. “But we actually see is that this is not quite right—there are negatives, but there are also positives. So, we’re trying to get a little bit more nuanced of a picture.” The team is working with teens with social anxiety and their parents over an extended period to better understand their social media habits and how their anxiety levels affect engagement with different platforms. The teens will answer questions sent to an app on their phones about mood and social media usage in an effort to capture emotional responses as they unfold. “We hope to develop interventions that can help make the best of social media while protecting against the more problematic effects,” Lebowitz says. The brain’s role in anxiety Researchers are also testing therapies to address anxiety at the neurological and molecular levels. In collaboration with Dylan Gee, PhD, professor of psychology in Yale's Faculty of Arts and Sciences, and Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience at Yale School of Medicine, Lebowitz and Silverman are using brain imaging to identify changes in a child’s brain before and after parents enroll in SPACE. In one study, children viewed anxiety-inducing images while undergoing magnetic resonance imaging (MRI); the researchers conducted scans with and without the children’s parents nearby. Before SPACE, children’s brains were better able to activate the regulatory circuitry needed to turn off an anxious response when their parents were nearby. But after SPACE, children could activate this circuitry even without the parent around. “As parents work on gradually reducing some of their accommodations, you can see a child get better at regulating their own fear system in the brain,” Lebowitz says. “It’s remarkable.” Research into the molecular underpinnings of anxiety can also inform new childhood anxiety treatments. In a recent study, Lebowitz, Silverman, and Flora Vaccarino, MD, Harris Professor in the Child Study Center, discovered that a protein known as fibroblast growth factor 2 (FGF2) could be protective from the toxic effects of stress. FGF2 levels in children and their parents were linked to the children’s risk of developing anxiety and depression, the study showed. The findings could help explain why some children who are exposed to early life trauma such as poverty or abuse are more prone to developing mental health disorders. And FGF2 could be a target for treatment. “This is very novel because it starts to give a clue to what is the molecular chain that connects those lived experiences to the actual psychological outcomes,” Lebowitz says. New ways to study and treat childhood anxiety Michael Crowley, PhD, associate professor in the Child Study Center, collaborates with Silverman and Lebowitz to study the role that attention plays in development and maintenance of childhood anxiety. There is a large body of research that shows that anxious children, like anxious adults, are prone to focus on threatening stimuli such as angry faces compared with neutral faces. This has led to innovative interventions that involve attention retraining. The idea is that if experts train children to look away from threatening stimuli, it may reduce their anxiety—especially children with social anxiety who are most prone to attend to threats. The researchers have just completed a clinical trial for attention retraining with 10- to 14-year-olds with social anxiety disorders and are currently analyzing the findings. Besides this innovative attention retraining research, as Crowly notes, “I like to design tasks that are engaging to kids,” Crowley says. “My goal is to assess something without the kids knowing what we are assessing.” With this goal in mind, Crowley has created a virtual game, named Boom, to study threat processing in children with anxiety disorders. The game is similar to that of hot potato—the child and three digital players take turns virtually passing a ball to each other’s gloves. At some point, the ball turns into a bomb, and as the bomb lands in each player’s glove, the outline of the glove turns yellow. The goal is to avoid having the bomb go off in your glove. What isn’t obvious is that the game is designed to measure different types of threatening stimuli, both ambiguous and direct. In the game, the direct threat occurs as the bomb is traveling towards your glove. The ambiguous threat is the yellow outlined glove as it is unknown where the bomb will travel next. While children play the game, Crowley’s team measures their brain activity using electroencephalography (EEG). The researchers have discovered that in kids with anxiety, the brain reacts more strongly to ambiguous threats than it does in their peers, but less strongly to direct threats. They believe that the initial abnormally large brain response to not knowing where the bomb is going impairs the brain's ability to properly respond when the threat is actually traveling the child’s way. “The brains of children with anxiety are unable to differentiate between threats you need to do something about and those that are not your problem.” Michael Crowley, PhD, develops innovative games for studying anxiety in children and adolescents.Credit: Matt Bradbury Based on these insights, Crowley hopes to study whether interventions like attention training could restore appropriate threat processing. Crowley’s team is also working on a test called the Balloon Risk Avoidance Task, which evaluates risk-taking and avoidance behaviors. It features a digital balloon that is full of air and about to burst. Kids have six seconds to let air out of the balloon. The more air they let out, the less risk they face that the balloon will pop. But at the same time, the balloon becomes less valuable as it deflates. “The more air you keep in the balloon, the more points you get,” Crowley explains. So far, the researchers have found that when the balloons pop unexpectedly, teens with social anxiety show distinct brain responses. Studying these responses can help psychologists understand the underlying pathways driving the various manifestations of anxiety. The genetics of anxiety When Thomas Fernandez, MD, associate professor in the Child Study Center and of psychiatry, was still in training, there was a lot of excitement about understanding the genetics associated with autism spectrum disorder. Since then, scientists have identified around 250 genes associated with autism. The genetic contribution to anxiety disorders, on the other hand, has historically received less attention. Anxiety is less heritable than autism, but the genetic contribution for anxiety disorders that emerge in childhood may be higher than for anxiety disorders overall. While scientists estimate the heritability of anxiety disorders in general to be around 30% to 50%, some studies suggest higher heritability for certain childhood-onset anxiety presentations. “I saw firsthand how researchers in the field went about finding vulnerability genes for autism,” Fernandez says. “So, we’re using a very similar playbook for childhood anxiety.” “I saw firsthand how researchers in the field went about finding vulnerability genes for autism. So, we’re using a very similar playbook for childhood anxiety.” Thomas Fernandez, MD Associate Professor In the Child Study Center and in Psychiatry Now, Fernandez and Emily Olfson, MD, PhD, assistant professor in the Child Study Center, are studying children and their parents to identify genetic changes that are present in the child but not the parents, known as “de novo mutations.” “All of us have some de novo mutations—maybe about 50 to 100 sprinkled throughout the genome,” Olfson says. “But when they occur within the coding regions of genes, they can be really disruptive.” Previous research shows that people with autism have higher rates of damaging de novo mutations than the general population. In 2022, Olfson, Lebowitz, Silverman, and Fernandez published a study on 68 children and their families that found that children with anxiety had similarly high levels of these mutations. Studying de novo mutations can help point the researchers to where they should be looking for genes associated with anxiety. “The end game is using the genes to steer us toward the right part of biology that we can then target to come up with better treatments,” Fernandez says. Building on those findings, the team is now studying more families to better understand how these de novo mutations, along with other genetic and environmental factors, shape pediatric anxiety disorders. They recently received a National Institutes of Health grant to enroll 750 new families over the next five years. Olfson is the principal investigator, with co-investigators Lebowitz, Fernandez, Silverman, and Shuangge Steven Ma, PhD, department chair and professor of biostatistics at Yale School of Public Health. Neurodevelopment, Risk Genes, and Mental Health Conditions - The Olfson Lab Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, is interested in how different anxiety disorders differ genomically. “We are studying social phobia, panic disorder, and generalized anxiety disorder, working to understand why people differ in their risk to these specific anxiety disorders and evaluating various risk factors,” he says. Gelernter was recently involved in one of the largest studies to date of the genomics underlying anxiety disorder. The study included around 122,000 people with anxiety disorders and around 730,000 without. It found that some genetic differences associated with anxiety were linked to signaling that helps reduce overactivity in the nervous system. Many anxiety medications available today work by targeting this process. “It’s nice when the biology that you get out of a large genome-wide study ratifies things that we already know because that can help increase confidence in further findings from the study,” Gelernter says. Uncovering the neurobiology of psychiatric disorders John Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and chair of the Department of Psychiatry, is interested in the neurobiology of psychiatric disorders, including post-traumatic stress disorder (PTSD), of which anxiety is a major symptom. In the late 1980s, Krystal’s team discovered that the drug yohimbine activated symptoms in patients with PTSD. “This was the first time we could link a specific biological mechanism to the symptoms of PTSD,” Krystal says. At the time, he adds, this finding was highly controversial. “A lot of people felt that PTSD was a purely psychological syndrome that didn’t have an underlying biology.” Since then, Krystal has dived deep into understanding the neurobiology of PTSD to learn how to better treat it. His team is evaluating the use of ketamine and psychedelics. These would be among the first treatments to be developed specifically for PTSD. They may also be applicable for other disorders including anxiety disorders, Krystal adds. An important gap in PTSD treatment is the absence of biological tests that inform how to best help patients manage their PTSD symptoms. A doctor doesn’t diagnose cancer based on how they feel. Rather, they use tests of the biology of the cancer to determine the best course of treatment. “And we can’t do that in any psychiatric disorder other than Alzheimer’s disease,” Krystal says. “But now we are building a foundation for this approach to the treatment of anxiety disorders for the first time.” Source: Yale School of Medicine
Penn State students win award for connecting health and environment through play
A series of games developed by a team of interdisciplinary Penn State students to help children in Iquitos, Peru, learn about the connections between human, animal and environmental health was recognized with a national American Society of Landscape Architects award.
Josh Allen held in check by New England
Josh Allen amassed 257 total yards and two TDs in Week 4, but it wasn't quite enough in a home loss to the Patriots.
Countries race to provide oral health care for all in 100-Day Sprint across Asia
Twenty Asian countries and areas across the WHO Western Pacific and South-East Asia regions vowed to strengthen essential oral health benefits as part of a “100-Day Sprint” initiative, during the 16th Asian Chief Dental Officers Meeting held from 27 to 29 September in Kota Kinabalu, Malaysia. The meeting marked the midpoint of the 100-day sprint bolstering support for countries to develop essential oral health benefit packages that can be integrated into national universal health coverage plans. Convened by the two WHO regional offices and the Malaysian Ministry of Health as the Secretariat, the meeting brought together national oral health leaders from 20 Asian countries, staff from all levels of WHO, WHO collaborating centres and other development partners. Participating countries and areas included: Bangladesh, Bhutan, Brunei Darussalam, Cambodia, China, Hong Kong (SAR) China, India, Indonesia, Japan, Lao People’s Democratic Republic, Malaysia, Maldives, Mongolia, Nepal, the Philippines, Singapore, Sri Lanka, Thailand, Timor-Leste and Viet Nam. Participants reviewed progress and refined proposals using the WHO Service Package Delivery and Implementation (SPDI) Platform. Countries conducted bottleneck analyses across four key areas: service delivery, workforce, access to essential medicines and health products, and health financing. They identified practical actions to address implementation challenges and refined proposed revisions to their national oral health benefit packages. “There is no health without oral health. Through the 100-Day Sprint, countries are advancing the implementation of the Western Pacific regional implementation plan on oral health and strengthening progress towards universal health coverage,” noted WHO Regional Director for the Western Pacific Dr Saia Ma'u Piukala. Participants identified bottlenecks and proposed workable solutions to strengthen access to essential oral health care through primary health care, sharing experiences and discussing how best to translate policy commitments into feasible and sustainable action at the country level. Malaysian Minister of Health Datuk Seri Dr Dzulkefly Ahmad highlighted the importance of prevention and primary health-care approaches to improve oral health: “Oral diseases can have lifelong consequences, yet many are preventable. By integrating essential oral health care into primary health care and promoting prevention in schools and communities, we can improve oral health across the life course.”The WHO team led by Dr Huong Tran, Director of the Division of Health Promotion, Disease Prevention and Control of the WHO Western Pacific Region and national oral health leads from over 20 Asian countries visited the SK Pekan Putatan School, Sabah for school oral health programme including flouride mouth rinsing. © WHO / V. ChaudharyDr Huong Tran, Director of the Division of Health Promotion, Disease Prevention and Control for the WHO Western Pacific Region, emphasized key collaborative roles WHO can play. “Oral diseases are the most common noncommunicable diseases, yet many can be prevented and treated through essential oral health services delivered at the primary health-care level,” she said. “By sharing experiences and using WHO tools such as the SPDI Platform, countries are accelerating progress towards universal health coverage for oral health.” “Integrating oral health into broader health services is essential for reducing inequities, expanding access and recognizing oral health as an integral component of overall health and well-being. The 100-Day Sprint provides an important opportunity to translate this commitment into practical action and ensure that quality oral health services reach all people, especially those most in need,” said Dr Suman Rijal, Director of the WHO South-East Asia regional Department of Healthier Populations and Noncommunicable Diseases. As host of the meeting, Malaysia showcased ongoing efforts to strengthen oral health care through primary health care and prevention-focused approaches, while providing a platform for countries across the two WHO regions to exchange experiences and accelerate progress towards universal health coverage for oral health. “WHO is encouraged by Malaysia's leadership in addressing the burden of oral diseases and advancing universal health coverage for oral health through practical, country-led action,” said Dr Rabi Abeyasinghe, WHO Representative to Malaysia, Brunei Darussalam and Singapore. Countries will continue to refine and figure costs for national oral health benefits during the remaining sessions of the 100 days. These efforts support implementation of the WHO Global strategy and action plan on oral health 2023–2030, while also helping to expand access to essential oral health services through stronger and more equitable health systems across the WHO Western Pacific and South-East Asia regions.______________For more information, or to arrange media interviews, contact: WHO Regional Office for the Western Pacific: wprocom@who.int WHO Regional Office for South-East Asia: SEMediaRelations@who.int
WHO joins Pre-COP31 to advance climate action that delivers for people’s health
The World Health Organization (WHO) is joining Pacific leaders, governments and partners at Pre-COP31 in Fiji from 5 to 8 October to advance health priorities in climate action and strengthen the Pacific voice ahead of the 31st Conference of the Parties (COP31) to the United Nations Framework Convention on Climate Change (UNFCCC).COP31, to be held next month in Antalya, Türkiye, marks an important step for global climate and health action. Health is one of the 10 priority themes of the COP31 Action Agenda, “Dynamic and Resilient Health Systems”, and a dedicated Health Day will take place on 9 November, the first day of COP31. The inclusion of health reflects growing global recognition that climate action and health are closely connected. The climate crisis is affecting population health globally. Across the WHO Western Pacific Region, which includes Pacific island countries and areas, the consequences of climate change include extreme heat, cyclones, floods, rising sea levels, food and water insecurity, infectious diseases and disruptions to essential health services. The Pacific in particular faces additional challenges. A recent review of 76 hospitals in 14 Pacific island countries found that 62% of health facilities are located within 500 metres of the sea or a river, leaving them particularly exposed to flooding, storm surges and sea-level rise.Bringing Pacific priorities to the global climate agendaThe Pacific Pre-COP31 provides an important opportunity for Pacific countries and partners to consolidate regional priorities and bring the experiences and leadership of Pacific communities into global climate discussions.Pacific countries have been advancing practical approaches to protect health in a changing climate, including strengthening climate-resilient health systems, improving preparedness for extreme weather events, building resilient health infrastructure and mobilizing climate finance for health. “This Pre-COP is an important moment for the Pacific, bringing global climate discussions to a region that has long been at the forefront of the climate crisis. It provides an opportunity for Pacific countries and areas to set their priorities, experiences and leadership on the global stage, and to ensure that the realities of Pacific communities are genuinely reflected in the decisions made on climate action,” said Dr Saia Ma’u Piukala, WHO Regional Director for the Western Pacific.Throughout this week, WHO will co-convene and participate in high-level discussions and events focused on climate and health, climate resilience, adaptation, financing and implementation. “Climate finance is essential for resilient and healthy Pacific communities,” emphasized Dr Mark Jacobs, WHO Representative to the South Pacific and Director of Pacific Technical Support. “We must ensure that financing reaches the people, communities and essential services most exposed to climate risks, supporting locally defined priorities and investments.”WHO will work with partners to strengthen the integration of health considerations across climate policies and investments, including national climate plans and resilience initiatives.Health as a driver of climate actionAmid the risks to health and pressures on health systems, well-strategized and implemented climate action can deliver significant health benefits. Investments in clean energy, sustainable transport, resilient infrastructure, food systems and nature-based solutions have proven to reduce health risks while contributing to climate mitigation and adaptation.“Climate action is truly an investment in health. Cleaner energy, healthier food systems and climate-resilient health services can protect lives while building stronger communities. We now need to turn these opportunities into action and make health a core part of climate investments,” said Dr Sandro Demaio, Director and Head of Office, WHO Asia-Pacific Centre for Environment and Health in the Western Pacific Region. “These benefits demonstrate that climate action is not only about reducing future risks. It is also an opportunity to improve lives today while building healthier, safer and more resilient societies.”At COP31 next month, WHO will also support the Health Pavilion, which will bring together the global health community and partners to advance health and equity within climate negotiations. With COP31 poised to move health higher on the global climate agenda, WHO will continue working with countries and partners across the Western Pacific Region and globally to strengthen climate-resilient and low-carbon health systems, and ensure that climate action protects and improves people’s health.____________________Media contactsElizabeth Bennett, WHO Asia-Pacific Centre for Environment and Health in the Western Pacific Region, elizabeth.bennett@who.intJulia Dongwhan Shin, WHO Asia-Pacific Centre for Environment and Health in the Western Pacific Region, dong.shin@who.intWHO Western Pacific Communications, wprocom@who.int
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Is AMC Entertainment Holdings (AMC) Fairly Valued As It Reshapes Debt And Governance?
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NJ Reminds Residents to Continue to Take Precautions Against Mosquito-Borne Illnesses
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