SCROLL NEWS / DISCOVERY
Search headlines
Find the stories shaping the conversation.
Results for " pic " 10,393 found 🔀 AI-powered Shuffle
Anthropic adds former Harvard science dean to oversight body
Anthropic said on Wednesday that Christopher Stubbs, former dean of science at Harvard University, had joined its oversight body, which holds the power to appoint a majority of the AI startup's board.Here are some details:
Researchers call for coordinated action to protect European sleep health
A new paper from the Equality, Diversity and Inclusion Committee and the Early Career Network of the European Sleep Research Society warns that sleep health is becoming a growing public health challenge across Europe and is calling for coordinated action to protect it.
A timeline of Mike Causey’s sometimes-turbulent tenure as NC insurance chief
A look at Insurance Commissioner Mike Causey’s career as a second complaint about his behavior with women surfaces.
Goodbye obesity, hello Ozempic: GLP-1 politics
The rise of Ozempic and GLP-1 drugs reveals how body politics, beauty standards, class and desirability shape ideas of the American body.
“It: Welcome to Derry” season 2 will be ‘a Warner Bros. gangster picture through the lens of Pennywise’ (exclusive)
Brad Caleb Kane teased what new horrors are coming for the 1930s Bradley Gang plot.
2026 Bowl Projections After Week Seven
Hello everyone, and welcome back to our weekly picks of who's in the playoffs and all the bowl games. This past week was circled on calendars since the schedules were revealed, with several top-25 matchups. However, it's doubtful anyone could have predicted what we saw, where five of the top seven teams in the AP …
Healthy rapport with doctor builds healthy habits for life
Rigley Bowar has been participating in Special Olympics since he was a youngster. Through it all, he has had the same primary care doctor.
Three Six Zero Launches Entertainment & New Media Division Led by Rebecca Dowell
Three Six Zero announced a new Entertainment & New Media division led by Rebecca Dowell, who will represent digital creators and emerging talent including…
Google CEO Admits Cloud Business Is Sacrificing Revenue to Win AI Race
Alphabet Inc. (NASDAQ:GOOGL) CEO Sundar Pichai says Google is giving up potential Cloud revenue to prioritize AI research, even as customers struggle to secure computing capacity. Google Cloud revenue surged 82% to $24.8 billion in the second quarter, while its...
Hurricanes pose long-term health risks for vulnerable older adults
New research in the Journal of the American Geriatrics Society indicates that older adults who rely on electricity-dependent medical devices-such as ventilators, respirators, and dialysis machines-may face substantial health risks during and after hurricanes, especially in communities experiencing severe flooding.
Special Olympics Chief Health Officer Dr. Dimitri Christakis Elected into the National Academy of Medicine
The National Academy of Medicine (NAM) announced the election of 90 regular members and 10 international members during its annual meeting on 19 October 2026. Among them was Special Olympics Chief Health Officer, Dr. Dimitri Christakis. One of the highest honors in the field, Dr. Christakis's election reflects both his work advancing health for people with intellectual and developmental disabilities at Special Olympics and his expertise in child development, particularly related to digital media and its effects on children’s social, emotional, and cognitive health.
These Americans make a living scooping poop for other people's pets: 'I truly love it'
Poop scooping is still a lesser-known service compared to the likes of lawn care and housekeeping. But these entrepreneurs are raking it in while picking it up.
After a few hours with Yakuza studio's soulful Stranger Than Heaven, I'm smitten, but I suspect this ambitious role-playing epic will be a divisive game
I played RGG Studio's Stranger Than Heaven, and came away impressed by the bold new direction its younger team is taking.
65 Switch 1 & 2 Games You Should Check Out In Nintendo's 'Screaming Deals' Sale (North America)
Every game we scored 9/10 or higher, plus a personal pick
<b>Doctors, engineers and computer scientists leave Israel.</b> Researchers sound alarm
The number of Israelis leaving the country has jumped by dozens of percent over the last three years, while the number of those returning has fallen. Researchers warn of a collapse of the Israeli economy if the trend continues
Boo at the Zoo, 'Clue Live on Stage!' and Bourbon Fest: 3 things to do this weekend
Our top 3 picks for your weekend
This concert was going to be the last at Red Hat as we know it. Now it’s canceled
It’s the end of an era. Here’s what to know about the final show and ticket refunds.
Who went home on 'DWTS' Week 6 from Dedication Night
Tuesday night was an emotional one on Dancing with the Stars as the reality show hosted Dedication Night. The 10 remaining couples all honored special people -- or places -- in their lives, often bringing the crowd, viewers and judges to tears. Former DWTS pro and two-time Mirrorball champ, Kym Johnson, joined the panel as a fourth judge this week.
Prominent Chester County business owner facing more child porn charges, police say
According to new court documents, the former owner of Harry's Hot Dogs, and several other businesses in Sadsbury Township, had pictures of teenage girls he knew that had been manipulated with AI to appear naked.
Laika's 'Wildwood' is rated PG-13. Here's how animation is changing
The PG-13 stop-motion epic opens Oct. 23. Can it draw teens and adults when even well-reviewed originals like “Forgotten Island” have struggled?
John Turturro on Hollywood, Oscars and getting better with age
Stealing the spotlight in his latest movie, ‘The Only Living Pickpocket in New York.’ the quintessential indie actor reflects on a career spent following his instincts.
Cowboys waive underperforming CB, promote Juanyeh Thomas, add Heisman-finalist QB
In his return stint, Juanyeh Thomas replaces former 5th-round pick Caelen Carson on the active roster. QB Kyle Trask joins the practice squad.
These Democrats could win competitive races. None are politicians
James Talarico and Abdul El-Sayed are far from the only atypical Democratic candidates running for Congress in the midterm elections.
“We were told…”: Why Dortmund stars fled before showering
After their narrow 2–1 win over Azerbaijani champions FK Sabah, Borussia Dortmund’s players left the Olympic Stadium in Baku without showering. The immediate departure on the BVB team bus was appa...
What Anthropic wants from a corporate writer worth $345K
Anthropic is hiring an executive writer for up to $345,000 a year. Here's what communication professionals say it means for young writers.
Amodei says Anthropic must stay in 'race to the top' to keep AI safe
Amodei said Anthropic would be best placed to make AI safe by staying at the top of the game.
Paul
Picture a press room full of journalists, a new signing at the desk, and an executive stepping up to announce: 'I can confirm that this is not an Inter player yet. He will be in a few weeks, once we o...
Extratropical Cyclone Whips Past Iceland
The powerful low-pressure system formed over the North Atlantic out of the remnants of Hurricane Isaias.
Talks on Montgomery health care authority care authority continue
A recently proposed health care authority was the topic of discussion at Tuesday night's city council meeting.
UC Davis Health introduces five-day accelerated treatment for severe depression
UC Davis Health has added an accelerated treatment approach for depression at its Advanced Psychiatric Therapeutics (APT) clinic in East Sacramento.
Student-produced film captures Ireland sports experience | UNC Hussman School of Journalism and Media
The documentary created by a UNC Hussman School of Journalism and Media team premieres on campus Oct. 22 and Oct. 23. — This story, written by UNC Hussman alumnus Michael Lananna ’14, was originally published at unc.edu. — Carolina senior Anna Laible came up with the idea about a year ago. At the annual UNC Sports and Entertainment Summit, the journalism student walked up to then-athletic director Bubba Cunningham and took a chance. “Hi, Bubba, I’m not sure if you remember me, but I’m part of the student broadcast team from the Olympics,” Laible told him. “I have this idea to do an Ireland documentary on the football team.” Encouraged by the enthusiastic response to the proposal, Laible and a team of students from the UNC Hussman School of Journalism and Media worked diligently to turn that vision into reality. In August, Laible and seven peers traveled to Dublin, Ireland, with the Carolina football team and women’s soccer team. Equipped with video cameras, the student journalists covered both teams during their international games — both wins — and filmed scenes throughout Dublin, interviewing Irish locals, Tar Heel fans and key Carolina figures who helped make the trip possible. Back home, Laible’s team put the finishing touches on the documentary, with its first screening at 6:30 p.m. Oct. 22-23 in Carroll Hall room 111. The project is the latest in a long line of sports documentaries produced under the guidance of C.A. Tuggle, John H. Stembler Jr. Distinguished Professor. Since the 2008 Beijing Olympics, Tuggle and the Hussman school have sent journalism students to cover each of the Summer Games, and Tuggle’s students have also produced documentaries on Carolina teams that win national championships. But this Ireland excursion presented a new kind of opportunity. “This trip is really unique,” Tuggle said. “Bubba liked the idea, so we started working on it, and it’s all because Anna was forward-thinking and assertive.” Laible’s team worked to create a holistic depiction of the Dublin trip, billed as “Much More Than a Game.” The documentary’s 12 chapters cover Irish culture, music, trips to the Guiness Storehouse and the myriad connections between Tar Heels and Ireland. “Our main focus was to make sure we gave a whole encompassing idea of what this experience was like,” Laible said. “We wanted to show not just the student-athletes, but other students, other Carolina fans, Carolina alumni, the music and really incorporate that all in the documentary.” Joining Laible in Dublin were juniors Emily Brietz, Cooper Hall, Eliza Jennings and Katherine McCullough and seniors Molly Malek, May Proctor and Merrily Tew. Those students also traveled to Milan for the 2026 Olympic Winter Games in February. Those kinds of opportunities wouldn’t be possible without the support of UNC Hussman and, in the case of the Ireland trip, the Carolina athletic department. UNC Hussman students create Ireland trip documentary. (Submitted photo) “Never in a million years did I think I would have the opportunity to go to the Olympics or to the Aer Lingus College Football Classic, and now I’m even being presented with potential opportunities go to the Super Bowl,” said Malek, who served in a leadership role with Laible in Dublin. “I think that Carolina does a terrific job of connecting us to these opportunities that almost no other university does. This is a university where you have the opportunity to have an interdisciplinary education and to learn and experience a lot of things all at once.” With the support of UNC Hussman, Tuggle and fellow students like Malek, Laible turned a spur-of-the-moment idea into a documentary. When the film screens, Laible said she’s not quite sure what emotions to expect. “I’m a little worried that I might cry — not that crying is a bad thing,” Laible said, laughing. “But I’m really grateful for so many people helping, and I’m excited for everyone to see it.”
Anthony Black Gets Brutally Honest About Contract With Orlando Magic
The former first-round pick reveals his mindset after missing the rookie extension deadline, addressing a mysterious injury and his commitment to winning despite looming free agency questions.
Rare solar radiation storm gives scientists clearest picture yet of flight risks
The most comprehensive data set ever collected from Earth's atmosphere during a solar radiation event has highlighted the importance of better-coordinated radiation monitoring for aviation safety, according ...
Moment of Science: New electric current test measures coffee quality without tasting
Getting a clue about the perfect brew! Here's how new research could make sure your morning pick-me-up is "not your average Joe". ☕
Glendale store owner sues federal government over cash, computers seized in raid 20 months ago
A Glendale convenience store owner filed a federal lawsuit Tuesday demanding the return of cash, computers and phones agents seized from his money services business in February 2025.
Would subsidizing weight-loss drugs make health care fairer?
GLP-1 medicines such as Ozempic, Wegovy and Mounjaro have transformed the treatment of obesity, but access to them in Australia increasingly depends on something much less medical: whether you can afford ...
Powder mailed to Arizona officials reflects surge in political threats
Suspicious letters containing white powder have targeted Arizona lawmakers and the state’s elections chief, as experts warn that threats and intimidation against public officials are rising.
Hospitals: Federal changes will worsen Minnesota healthcare crisis
Minnesota hospitals had a record high of over 2 million emergency department visits in 2024. That year, more than a quarter of hospitals lost money on operations. The Minnesota Hospital Association painted a bleak picture of Minnesota healthcare Tuesday in a new report titled “A Statewide Crisis of Care.” The hospitals are gearing up for […]
How to teach graph skills in science lessons
Translate graph skills into a science context with these teacher-tested tips
‘Immature’ Ex-Dallas Cowboys RB Released by Eagles
Former Dallas Cowboys RB & 2025 NFL Draft pick released by Philadelphia Eagles. The post ‘Immature’ Ex-Dallas Cowboys RB Released by Eagles appeared first on HEAVY.
New Richland Lab Could Transform How Scientists Study Microbes and Boost Regional Jobs
The BriefGroundbreaking held Tuesday: PNNL officially began construction on the M2PC lab, a 30,800-square-foot facility funded by the U.S. Department of Energy's Office of Science that will study soil microbes to improve crop productivity and develop new biotechnology applications. The facility will be open to researchers from around the nation and the world.Research timelines could shrink dramatically: The facility's automation and AI capabilities could reduce experiments that currently take six months to just 72 hours, allowing scientists to explore more possibilities faster than ever before.New jobs coming to the Tri-Cities: The project is expected to create positions for automation engineers, AI experts, roboticists, technicians, and skilled craftspeople, with the facility opening in 2029.RICHLAND, Wash. — Pacific Northwest National Laboratory broke ground Tuesday on a first-of-its-kind facility that could accelerate scientific discoveries about the microscopic organisms living in soil—organisms that may hold the key to growing more food and developing new energy technologies.The Microbial Molecular Phenotyping Capability, or M2PC, represents a significant investment in automation and artificial intelligence to speed up research that traditionally takes years to complete. The 30,800-square-foot facility will house more than 100 connected automated instruments designed to study microbes at a pace and scale never before possible.Reshaping Agriculture's FutureThe M2PC facility will not put a new tool directly into a farmer's hands tomorrow morning, but it is actively reshaping the commercial pipeline to solve agriculture's biggest headache with biologicals: inconsistent field performance. For years, PNNL researchers have explored how microbes work and how they might help produce useful materials, advance energy technologies, and address challenges involving critical materials and minerals. But those experiments have been limited by what researchers could accomplish by hand."They can be used to provide nutrients to a plant so that the plant would grow more. So, like increasing your crop productivity, for example," said Douglas Mans, PNNL's Associate Laboratory Director for Integrated Discovery Sciences.PNNL's own research shows soil microbes can help plants access nutrients and withstand drought—benefits that could prove crucial as farmers face growing environmental pressures. The M2PC facility will allow scientists to identify and optimize useful microbes faster than ever before, accelerating the development of biological solutions that actually work consistently in the field.What Makes M2PC UniqueThe Microbial Molecular Phenotyping Capability differs from traditional research labs because it operates as a first-of-its-kind, AI-enabled autonomous laboratory designed to shrink experimental timelines from years down to months or weeks. The M2PC lab will connect more than 100 automated instruments to grow microbes, prepare samples, measure their behavior, and link observations to the molecular processes behind them. Artificial intelligence will help analyze results and guide the next experiments, allowing scientists to explore more questions faster.Deb Gracio, PNNL Director, emphasized the transformative potential during Tuesday's groundbreaking ceremony: "Research that has taken years will become possible in months and hopefully in weeks."That acceleration is already being demonstrated. PNNL's smaller automated lab, called the Anaerobic Microbial Phenotyping Platform or AMP2, completed three experimental cycles in just 72 hours—a process that normally would have taken about six months."That normally would have taken us about six months … and we were able to do that in 72 hours," Mans said.The AMP2 laboratory is not being closed or replaced. Instead, the current 1,800-square-foot laboratory serves as an active prototype and precursor for the much larger M2PC facility. AMP2 will continue operating as a separate lab designed to run anaerobic experiments—those conducted in the absence of oxygen—while M2PC will focus on aerobic research.Broader Applications Beyond AgricultureWhile improving crop productivity is one important application, the M2PC facility is designed to support research into multiple areas critical to national priorities. The lab will advance research into biofuels, manufacturing materials, and energy technologies. It will also help researchers understand how microbes respond to environmental changes and how to design biological systems for biotechnology applications.As a flagship component of the Department of Energy's Genesis Mission, M2PC represents a significant investment in using artificial intelligence and automation to accelerate U.S. scientific discovery. Dorothy Koch, Associate Director of the DOE Office of Science Biological and Environmental Research program, highlighted the facility's importance during the groundbreaking."M2PC will accelerate biological discovery and design," Koch said, noting that the facility is expected to conduct a minimum of 500 strain experiments per week, 100 microbiome experiments per week, and take a million measurements per month.Economic Opportunity for the RegionBeyond the scientific breakthroughs, the M2PC project represents significant economic opportunity for the Tri-Cities region. The facility will require hiring automation engineers, AI experts, technicians skilled in operating robotics, and specialized craftspeople to build and maintain the sophisticated equipment."We're anticipating that type of hiring," Mans said when asked about job creation.PNNL has already begun recruiting talent nationally and internationally for positions related to the smaller AMP2 lab, bringing automation engineers from cities like Boston and San Francisco to work in the region. The M2PC facility is expected to accelerate that trend."This capability won't really exist anywhere else in the world," Mans said, suggesting the facility could become a draw for scientific talent seeking to work on cutting-edge biotechnology research.Timeline and Next StepsThe M2PC facility is expected to open in 2029. Between now and then, construction crews will level and prepare the ground, while the building takes shape. Simultaneously, Ginkgo Bio Works, the automation contractor, will build the facility's automation components off-site so they can be installed as the building is completed.In the interim, PNNL researchers and the broader scientific community will begin planning the first experiments to be conducted in the facility, ensuring research is lined up and ready to begin as soon as the doors open.The groundbreaking ceremony included representatives from the Department of Energy, PNNL leadership, and elected officials at the federal, state, and local levels, underscoring the project's significance to the region and the nation's biotechnology future. News The U.S. Department of Energy Secretary tours Pacific Northwest National Laboratory Dan Hanson, Apple Valley News Now News Beyond DNA: Scientists Explore New Frontiers in Biology Research Dan Hanson, Apple Valley News Now News TRIDEC optimistic that Hanford, PNNL will see funding in national budget Robert Desaulniers News Big picture science: monitoring the Yakima River Basin News PNNL research could shape the future of fighting fentanyl COPYRIGHT 2026 BY APPLE VALLEY NEWS NOW. ALL RIGHTS RESERVED. THIS MATERIAL MAY NOT BE PUBLISHED, BROADCAST, REWRITTEN OR REDISTRIBUTED.
NBA: Detroit Pistons stage epic 22-point comeback to defeat Boston Celtics as season tips off in style
Detroit Pistons rally from 22-points down to beat Boston Celtics 121-113 with Javonte Green and Cade Cunningham’s 22 points and 8 assists winning the day at Little Caesars Arena
Sacramento news roundup: ICE incident, seized business and energy rank
From a congressman's call for ICE accountability to a State Bar raid that hauled off 14 boxes of files, here's what's driving Sacramento conversation.
Commentary: The slime machine in Ohio politics has reached a despicable new low in the 2026 election
I knew 11 years ago that our public discourse would be degraded down into unfathomable levels. The 2026 campaign in Ohio has now confirmed it beyond anything I could've imagined.
Penn State expected to miss Bowl Games by multiple outlets
Penn State was nearly a consensus College Football Playoff pick earlier this year, and now they are expected to miss out on Bowl Games.
Is Mold in Coffee a Real Problem? Here Is What the Science Says Before You Panic
Is mold in your morning coffee actually a problem? Food scientists say probably not and here is why.
UC Davis may develop new Lake Tahoe science and community hub. Here’s where
The university has entered into a partnership with Placer County to explore a new project at three underutilized county properties.
Detroit Pistons Stun Celtics With Epic Fourth Quarter Comeback
Detroit Pistons overcome a 22-point deficit with a stunning 23-0 fourth-quarter run to beat the Boston Celtics 121-113 in their 2026-27 season opener.
‘Wildwood’ review: Laika’s stunningly animated epic is a visual wonder
"Wildwood," the latest release from stop-motion studio Laika, shines bright visually. Its story, though, is quite a bit darker, writes our reviewer.
PHP warns admins of two critical flaws, emergency patches coming tomorrow
The PHP security team is warning administrators to prepare for emergency security updates tomorrow to address two critical vulnerabilities, as information about the flaws has reportedly leaked ahead of their scheduled disclosure.
Feds hold back an additional $1.2 billion in California Medicaid reimbursements
In May, the administration held back $1.3 billion in Medicaid reimbursements to California over concerns about "fraudsters" in the state's hospice and in-home care programs.
Hackensack Meridian Health signs definitive agreement to acquire Hunterdon Health, commits $230M
Hackensack Meridian Health has signed a definitive agreement to pick up Central New Jersey’s Hunterdon Health, a $230 million deal that would grow the state’s largest health system to 19 total hosp | The announcement did not outline a potential timeline for the merger, which would add a nineteenth hospital to New Jersey's largest health system.
The truth of 'Dancing with the Stars' – What training with a pro is really like
Editor's note: Anna Kaufman is a former reporter at USA TODAY, who trained with a pro dancer from "Dancing with the Stars" to see what the process is really like. This story originally ran in November 2025.
How ‘You Can See Everything’ can get an Oscar acting nomination for [SPOILER]
‘You Can See Everything’ is aiming for historic Oscar nominations, including in Best Picture and acting.
Sen. Banks among politicians receiving ‘potentially hazardous’ letters under investigation by FBI
Indiana Senator Jim Banks (R) reportedly received suspicious mail as federal authorities investigate a string of such instances involving politicians nationwide.
Weekday Drop-In Recreation at Sports Factory
Stay active throughout the year with healthy exercise by walking laps or playing basketball, pickleball, or volleyball at Sports Factory.
Meeting Big Challenges with Big Ideas, Health Centers Pitch ‘Y Combinator-Style’ Solutions for Local Healthcare
With challenges looming like Medicaid cuts, workforce shortages, and resource gaps, health centers across the United States are being asked to do more with less, and it would be easy to picture a g…
Going with the Flow - College of Arts and Sciences
Scott Gifford studies the microscopic organisms that shape water quality, ecosystems, and Earth’s climate.
Sundar Pichai: Google’s Frontier Imperative, Compute Scarcity Dilemmas, Future AI Products and Businesses
Alphabet CEO Sundar Pichai has little patience for doubts about Google’s willingness or capacity to compete at the frontier of AI. His company’s latest Gemini 4 Argon model — long-promised and recently delivered — beats OpenAI and Anthropic’s latest public models on coding, math, science, and knowledge-work benchmarks and has placed Google’s AI back among the world’s best. Amid chatter that Google was fine with good-enough lightweight ‘Flash’ models, Pichai pushed back hard against any suggestion that company is limiting its research ambitions. “We won’t do it any other way,” he told me in a Big Technology Podcast interview recorded this week at Google’s Mountain View headquarters. Pursuing cutting-edge research is costly for Google, requiring compute and chips that otherwise could be sold at a high markup by its cloud business. But Pichai said allocating resources to frontier AI development is “ground zero” for Google. “Our cloud business is at any given moment in time forgoing short-term revenues because we are making compute trade-offs to support frontier AI development,” Pichai told me. In our conversation, we discussed Argon (which Pichai says processed three times as many tokens as Gemini 3 in the 72 hours after launch), AI’s role in developing better models, the AI interface of the future, competition with OpenAI, Google’s partnerships with Anthropic and Apple, data centers in space, and the nature of his optimism. You can read the full conversation, lightly edited for length and clarity, below, or listen to it on Apple Podcasts, Spotify, YouTube, or your podcast app of choice. Alex Kantrowitz: Google is back at the frontier with Gemini 4 Argon, which beats OpenAI’s and Anthropic’s public models on benchmarks spanning coding, math, science, and knowledge work. The conventional wisdom was that Google had given up on the frontier to focus on fast, good-enough models for its products. That was wrong? Sundar Pichai: Very wrong. Look, we are so committed to being at the frontier. It’s in our DNA. We won’t do it any other way. We’ve been thinking about the AI frontier for well over a decade now. The frontier is very dynamic. It’s very competitive. It’s very exciting. I couldn’t be more pleased with how Argon has come together. We took our time with it. We made sure we tested it safely and deployed it carefully. We took a bit longer than our other models, given its capabilities. Across the board, be it for agentic work, knowledge work, coding, creative tasks, Argon is one of the really good frontier models. The first 72 hours since we launched, it’s almost up to 25 trillion tokens used, which is about three times what Gemini 3.0 had in the first 72 hours. And we are capacity constrained as we are serving it. Excited, but there are always areas….. You know, the frontier is very dynamic, and you have to keep evolving the models. There are areas which we can see we need to improve as well. We’ll be at work on all of that as well. Which areas? On any given model, Argon would be across the board better at everything if you just look even two months back. But the space is so evolving. Even on coding, for example, there are pockets where we know we need to do better, and there’s clear feedback. We’ll make it better. The argument for standard models is that they’re already good enough to build great products, with the frontier valuable only for certain tasks. Meta built Muse with good models rather than the best, and Google could put standard models into Maps, Gmail, and Search. Why isn’t that sufficient? It’s definitely not how I have thought about it at all. We are deeply committed to driving the state of the art and actually pushing where this technology can go, all the way from transformers. That’s a journey we’ve been on. You will see us continue to do that. When you’re at the frontier, you get an earlier look into the emerging capabilities, earlier than others, which helps you better prepare for the future. We are fortunate to have a wide set of opportunities across consumer and enterprise. Some of our cloud customers, for sure, want the model at the frontier. The frontier models will be better at developing the next set of models in an era of recursive self-improvement. I would argue it matters there. Internally, we have definitely seen a steep point of inflection by deploying Argon to our developers. It definitely tackles problems which our previous models could not do. Being at the frontier puts you at the innovation frontier and helps you drive that as well. There is room for models of all sizes and capabilities. That’s why we did Flash, Flash-Lite, etc. I agree with you that you can develop very good product experiences with not necessarily the most frontier model, because they tend to be slower and more expensive too. But we care about the Pareto frontier, and we’re committed to doing all of that. You said developing frontier models gives you a look at what’s coming. What do you see on the horizon? What makes this moment so exciting is you build something which you think is a culmination of months of work, and you put it out. You already see clear headroom ahead. We’ve all been working on these agentic, long-horizon capabilities, but clearly the frontier is going to have multiple of these agents working together to do things. That’s an example of an exciting paradigm underway. It’s also clear to me that users, both in consumer and enterprise, will have access to some multi-agent framework for them, working all the time doing things. It feels like a moment of infinite possibilities. Sergey Brin said one of Argon’s core innovations was relying more on the model to help develop the model. Yet incidents involving OpenAI’s bots breaking containment and Google’s bots accessing a site they shouldn’t have suggest these systems still aren’t perfectly aligned. Isn’t there reasonable cause for concern about accelerating toward recursive self-improvement? There are three parts to your question. Let’s first talk about RSI itself. You’re right, Sergey mentioned RSI being a critical contributor as we are developing Argon. But to be very clear, today, in a continuum, we are pretty far from the end state of RSI or something like that. The right way to describe it is you have RSI loops along with AI researchers in various aspects of model development. You almost have agents helping AI researchers in some automated way work together to build these models. It’s good to at least understand where we are today, and it’s super exciting. I expect that continuum to keep making progress as we go into next year. The second question is around safety. Security comes from defense in depth. You’re talking about alignment, obviously. We all are doing a lot of work to make sure the models are as aligned as possible. But it’s an active area of research, and there are clear gaps. That’s not the only thing we rely on. You have the work you do on alignment, but beyond that, we put a lot of effort into real-time monitoring as these models are working. Making sure you have good telemetry into what’s happening so that you can intervene in real time if you see unexpected behaviors. How you do that, the architecture with which you do that, how you make sure it’s all sandboxed and isolated in a way that it can continue doing its job during real-time monitoring — these are all areas of investment. Obviously, when we deploy these models, giving customers, enterprises, control, both with real-time monitoring, but their ability to decide where they deploy, what type of data which models ever have access to, etc. All that work is very, very important, and we are doing a lot of that. As an industry, we need to constantly up our game and take the time to do all this stuff, including dedicating the compute required to make sure you can safely deploy these models. The third part is: Is it all enough? This is why there are a lot of conversations in the industry, and I think it’s reasonable to be worried. The right way to approach something you worry about is early on thinking about what more we can do. As an industry, you’re definitely seeing increased levels of work on alignment, testing for safety, etc., as we deploy these models. The next step would be developing better standards so there are cross-industry standards of how we do these things, including the ability to evaluate using independent evaluators. If you look at areas like financial controls, we have accounting standards, we have independent auditors. Those are all the next natural steps for us as an industry to work toward, and regulation will end up playing a role as we go through all of that as well. Google pursues both language models and world models, while some other AI companies like OpenAI have focused more heavily on LLMs as the path to AGI. Why is world-model research important to you? As humans, you obviously perceive the world around you, and you’re taking all those inputs. Making sure these models are able to understand the laws of physics, simulate the world in high fidelity. All that, I think, are key enabling blocks for intelligence. We are working across all possible applications of this. Take an area like robotics. It’s not an accident: If you look at embodied reasoning benchmarks, Argon is state of the art. That all comes from our experience building world models. Inherently, I would expect there will be architectures which will converge all of this in the future. But for us, we view this as, today, this jagged frontier that is intelligence. We want to be at the frontier of all the possible approaches, and that will help us both drive better research, better insights, and develop a much better AGI model, is how we think about it. Some people argue Google should focus on selling its computing resources rather than using them for AI research. Cloud wants to sell compute at a high markup, while researchers need a very big computer to build the best models. How do you balance those demands? Ground zero for us is making sure we are investing in the compute that’s needed to be at the AI frontier. In 2015, I set the company to be AI-first. AI is that key horizontal ingredient across everything we do, all the way from Search to Cloud to Waymo. That is ground zero for us, making sure both for research and developing the models that we have enough compute needed. Beyond that, we have these independent businesses which each have their own long-range plans. They’re using those long-range plans to project forward, and we plan for compute for all of them. The cloud team, they have a business and they have a projection and they have demand signals. They have committed contracts. With that help, we can plan on a long-term compute trajectory for them. We’re fortunate to have this wide set of opportunities. There’s no company in the world which isn’t making trade-offs at any given moment in time. But the first principles we operate on is making sure we have enough compute to invest in the frontier, and that’s non-negotiable, and everything else works on top. Remember, we are building our own compute, our own data centers. There are long lead times. The compute we have today is a function of decisions I made in 2024. Even if you think back to a year from today, last year the agentic coding takeoff hadn’t happened. Today, obviously, when you sit and look at anything, everyone is short—not just us, other companies—and everyone wishes you had two times what you had planned for. That comes with the territory. At any given moment in time, we are planning for what we would need two to three years out in the future. You’re going to find some decisions you make may look suboptimal two years out, depending on where the state of the art is. I don’t spend too much time thinking about it. The way I think about compute allocation is making sure Google DeepMind, both for research and frontier model development, is cutting edge in terms of compute access. After that, we plan for all our businesses. It’s great we can provide our compute to other people too, like we have done. It allows us to scale that up, get real tests for it in the widest application set possible, test it in the real world, and make sure we are at the cutting edge of technology at every layer of our AI stack as well. Ben Horowitz relayed on a podcast that Andy Jassy had said compute was sold out until 2028. Are you seeing the same thing? If today a customer is coming out and asking us for compute in ’27, that is incredibly difficult to do. Even last year we went out and leased some short-term compute to accommodate some customers and help them out. But yes, we are all dealing with similar timelines. Every major technology shift seems to involve overbuilding, from railroads to fiber. Do you think that’s happening here? It depends on the time frames you’re looking at. This level of build, if I take a long enough time frame, it makes complete sense to me. We are at early stages of the most consequential technology ever, and this is not like fiber. It’s not dark. We are using it. We are capacity constrained on a daily basis. The applications, the underlying technology is improving rapidly. But running a company, the way I work through the moment is you look at your demand signals. You look at your committed revenue opportunities that you’re getting in the form of contracts. You balance that with the underlying technical capability, or internally you balance how we are using it internally, the model trajectories. Based on all that, you take a disciplined approach—a confident, aggressive, but disciplined approach—to plan out compute. But when you talk about the broader economy as a whole, you’re having people operate with various levels of risk. I focus on what I can control as a company and plan through it. If your question is, can there be an overbuild? Yes, because you can have some constrained components. Remember, what matters is a set of everything you need to build out that compute. Memory, electricity, electricians…. Land. Like 2,000 components or more. You could get constrained at some point. There could be things which cause bottlenecks, and then you could have overbuilds. There could be external shocks to the economy. There are macro risks. All that is possible at any given time. But am I confident that the compute we are planning for, we will have uses for it given enough time? Absolutely, yes. I was in the room when you said AI would be as profound as fire and electricity. If you believe that, shouldn’t you give researchers the biggest possible computer, even at the expense of today’s cloud profits? We’re all doing some form of that. Our cloud business is at any given moment in time forgoing short-term revenues because we are making compute trade-offs to support frontier AI development. What you’re seeing is true already. But you want to be thoughtful. Even our AI researchers have some constraints, which are also good. That’s what inspires creativity. That’s what helps you come up with a more efficient algorithmic breakthrough, maybe to use less memory. What we are committed to is to invest what’s needed to stay at the frontier. OpenAI President Greg Brockman told me a few months ago that the ideal AI product might have no interface at all—just as natural as conversation. What do you think the interface looks like in the age of AI? Computing historically has been humans adapting to computing. With AI, it’ll be the other way around. The technology will adapt seamlessly to how humans live and go about their day-to-day life. You want to be able to speak to that AI when you want to. It has context. It can be persistently running somewhere, give you continuity. You’re not dealing with a lot of complexity. It’s natural. All that makes sense to me. That doesn’t mean it won’t have any interface, however. Nowadays, even on my phone, Gemini voice models are so good. I can just press the microphone button. I can just ramble. That’s why we call it Rambler. I can ramble. It intelligently corrects with my personal context. Even my friends’ names, weird names, it gets it right, even if it first guesses it wrong. It’s amazing. I’m not going in, backspacing, editing once I finish saying it. It’s remarkable how good it’s gotten. But there are going to be moments you will need an interface. You may want to entertain yourself. You may want to watch a video. You may ask your AI to create something, and you want to watch it, consume it. The way I think about it is, you want it to be as seamless and as natural as possible, and that you are not doing the hard work adapting to whatever the interface is. The technology is adapting to how you’re working at any given moment in time. When I asked Sam Altman about competition from Google, he argued that OpenAI was building AI-native products and implied Google was bolting AI onto existing ones. Do you accept that framing, and can a “bolt-on” compete with an AI-native product? First of all, it’s a very dynamic moment. We are all pushing each other. OpenAI has pushed us as a company too. This is not just we are doing something to them. Far from it. Yes, Google went into its own version of a code red too. In the AI moment, all of us have to respond with varying levels of urgency at any given moment in time. We are constantly building new products as well. Gemini was built from the ground up as a product—the Gemini app I’m talking about. Or tomorrow, as all of us are adapting to agents, are you bolting agents onto ChatGPT, or are they building it natively? How would you think about that? You can always put these questions back. I don’t think of it that way. I think of it as you want to build world-class product experiences that are AI-native and they are winning. Some of it is adapting products, some of it is rethinking new experiences. They will all be part of how you approach this moment. How do you expect to make money from these AI interfaces? If an agent recommends a product and I buy it, should it take a cut of the sale, even if that’s disclosed? I’m going to put enterprise aside. Consumers are going to increasingly value this technology. Take software developers today. Developers are willing to pay for these coding models because it really helps make them more productive. Nobody would want to code the way they were coding three years ago, or even the same time last year. When you’re delivering value, there’s value to be had. I’ve never seen examples where consumer products really scale to billions of users, where people are using it intensely, and haven’t had monetization to go along with it. If you’re providing value to people, there is inherent value to be had. The nature of it may change. You’re asking a scenario in which agents are doing stuff for you. At the end of the day, you will have commercial needs. The agents need to fulfill those commercial needs. The providers on the other side are going to see value in that. There’s going to be some mechanism by which it gets fleshed out. That’s what an efficient system does. But what matters is that you’re building those world-class consumer experiences. I promised myself one product feature request: Can you make Gemini-powered search in Gmail as good as searching Gmail through ChatGPT? What’s going on here? One of the exciting things we announced recently is the unified Gemini agent for enterprise, and we’re bringing that to consumers. These are persistent agents which run 24/7 in the cloud. We’re spinning up a micro VM effectively for every query, and from the runtime, the harness, the model—it’s all a headless service. It’ll work everywhere, and it has your context with you. You can address this agent whether you’re in Workspace, in Search, in Gemini. Agents are going to drive this unification from a customer experience, which people are looking for. When you have a broad product portfolio and you’re moving forward fast, there are always areas where you’re moving forward faster than some other areas. That’s valid feedback. But we are putting a lot of time and effort into making sure, as we build out our agentic experience, that unification and that capability works well across all these services. People have asked where Google’s equivalent of Muse or Dots is. Do you anticipate creating a new product to compete with them? Our goal with Gemini is to be a personal, proactive, and powerful assistant. That’s what we are working toward. You saw us describe the early versions of it at Google I/O this year with Spark. Effectively, already, if you open the Gemini app as a Pro or an Ultra user, you see Chat and Task, and they start giving you that agentic experience. With Argon now, that capability is dramatically accelerated. What we announced recently in our enterprise event, we are bringing that to consumers as well. Soon in Gemini, you will be able to ask something, and it’s a continuum. You don’t need to think about whether you’re asking a chat or an agentic task. It’ll just automatically do the right thing, and it can work persistently in the background securely and get things done for you. Already, empirically, when I look at what’s coming into Gemini in our app, last year you would have tagged them and most of them would have been chats. But a steadily growing percentage is already agentic tasks in Gemini. Yes, we are going to bring personal agents to our consumers. It’ll work in the Gemini app. It’ll work in Google Search. It’ll work in Gmail. You can address it, call it, etc. We want to make sure we’re getting it right. It’ll be powered by Argon, and we are very excited to bring it to our users. Google has invested and committed tens of billions of dollars to Anthropic. What do you see in Dario Amodei that makes you want such a deep investment and partnership? Very early on, when we looked at the founding team of Anthropic, it was very clear to us this was a world-class team which was involved in some of the earliest GPT models. We were quickly able to assess that they would be at the frontier. We’ve always tried to identify and partner with companies which would be at the cutting edge of technology. We’ve done that with SpaceX. We’ve done that with Anthropic. That’s what we saw, and we had a chance to partner. Is your partnership with Apple to license Gemini for Siri expanding, contracting, or standing still? For both us and Apple, that partnership was about translating the capabilities of AI into better experiences for users. I thought Apple has done a phenomenal job of incorporating—they customize these models and build it into Siri—and it’s been great to see the reception. We are committed to doing more. You’re going to do more with them? There’s nothing specific to comment, but it’s a partnership. It’s working well. What have you learned so far about the feasibility of data centers in space? It’s a very exciting project. Projects like this remind me—I still recall that moment in the desert for the DARPA Grand Challenge, watching the Stanley car compete in it, which ended up being the basis for Waymo. With all these technologies, you’re at a moment in time where it looks a bit like sci-fi, but 10 to 20 years down the line, it’s actually working in a meaningful way. I feel the same in space. We’ve always believed in betting big on these technologies. Quantum has been a great example of it. We’re probably 10 years into the journey. Waymo, we are almost 20 years into the journey. Space, we are two to three years into the journey. It’s clear to me that it’s an approach which will make a lot of sense in the future. Being in sub-synchronous orbits with 24/7 access to the most abundant form of energy we have access to will make a lot of sense for this exponential increase in compute that we are going to need. Having said that, this is a challenging project. The team has disciplined milestones. It was a super exciting milestone to send the TPUs up to space. Sometime, as we are speaking, we are expecting a “hello world” moment from them. I look forward to seeing that happen, and we’ll continue investing here too. You previously said 25% of the code written within Google was written by AI. What’s the number today? That number in our world today is meaningless in the sense that every part of what we now touch is influenced by AI deeply. What we are tracking with Argon, for example, it’s been a point of inflection. People are using Argon to really go tackle complex projects, including projects which affect millions of lines of code. In the four weeks since we have launched Argon, we have seen a 30% increase in CLs, and more importantly, almost a similar increase—a one-third decrease in rollbacks. People are writing code more productively and better code with it. We are tracking it with newer metrics now. How are you dealing with opposition to data centers? If you can’t build in the U.S. the way you want to, where else do you go? We’re very committed to building our data centers very responsibly. When I look at our largest data centers in some of the communities where we have been the longest, I visit them, I talk to people. There are people who come and tell us their kids have gone to college because of our investments in these communities, and we’ve grown in those communities. To me, this is about doing it right. Engaging with the communities early, doing it transparently. We are committed to making sure we are bringing incremental power, and we cover 100% of the cost of our power needs for these projects. It’s understanding the impact on neighborhoods and making sure you’re working thoroughly to address them. Done rightly, you can continue making progress. But we are constantly taking feedback into account. I do worry not everyone operates the same way. People have been surprised by data centers showing up in their backyard. Those are all important. As an industry, we should continue to do better. But part of the reason, in a 20-year time frame, we are thinking about things like data centers in space is making sure we are able to put these data centers where maybe the trade-offs will be different. What unproven area of AI is Google working hardest to crack? Is it continual learning—getting models to keep updating after release—or something else? There are multiple parallel paths. You saw with Argon we have a million output tokens. With our Gemini models early on, we had a one-million context window on the input side. These are all examples of breakthroughs we are constantly working on. How do you think about synthetic data? How do you think about continual learning? How do you think about more efficient architectures? We do dedicate a meaningful percentage of our compute to these research bets too. It always goes hand in hand, including our world models. Those are all bets we are placing. Sometimes, as part of these bets, there are ideas that emerge which just make their way into the mainline models. Maybe we don’t fully talk about it, but we have multiple steps in these areas. Working in technology requires optimism that building something will improve the world, but those bets can leave real consequences when they fail. I recently returned to a town in El Salvador where enthusiasm for Bitcoin had given way to unfinished construction and something resembling a ghost town. How do you maintain the optimism you spoke about in your Stanford commencement address while accounting for those risks? I genuinely have a deep conviction that improving technology and improving access to technology makes people’s lives better. It’s been my personal experience in my life, out of which comes that deep conviction, optimism. But with that, I’ve always felt humanity’s journey is always about working hard to harness that technology to make it work well for society. The optimism is not an optimism that you just build whatever you want, whenever. You work hard to make sure you’re building technology in the service of humanity, to make the human condition better. That’s got to be the defining goal as we are approaching it. With that framework, I’m very, very optimistic. We are in very early stages of the kind of progress that we are going to see on many areas. We’re all talking about areas like healthcare. A lot of the progress is ahead. The ability to make things in a fundamentally cheaper way on many things where things have been getting expensive for a long, long time, discovering new materials, etc., which really bend the curve—it’s tough to step today and understand the impact of all that, but they’re going to be very profound. I’m very optimistic, but we have to be rightfully concerned about all the ways this technology can go wrong. Sundar, I know you don’t do many of these. Thank you. Thanks, Alex. Appreciate it.
Minnesota Vikings Trade Steam Picking Up Early
The Minnesota Vikings are 5-0 with three weeks until the trade deadline, and the trade chatter continues to grow louder.
DreamWorks Shrek 2 Remastered announced for PS5, Xbox Series, Switch 2, Switch, and PC
Aspyr has announced DreamWorks Shrek 2 Remastered for PlayStation 5, Xbox Series, Switch 2, Switch, and PC (Steam, Epic Games Store). It will launch on November 10 for $29.99.
Google says Chrome’s Safe Browsing Enhanced Protection mode makes users 10x safer
Chrome today announced the latest features for Safe Browsing Enhanced Protection. Google says this mode makes users ten times safe...
Harms of Public Health Measures Overlooked in COVID-19 Policy Reviews
Investigators link oversight with eroding trust in health authorities and call on future pandemic inquiries to weigh trade-offs.
Ana Navarro shuts down ‘View’ cohosts for joking during tense Donald Trump discussion topic
Ana Navarro shut down ‘The View’ cohosts Sara Haines and Alyssa Farah Griffin for making light of a serious, tense topic related to Donald Trump: ‘Stop, this is not funny.’
There's A Suspicious-Looking Hole On The Moon, And NASA's Going To Investigate It With A Surface Mission
The Moon is covered in pits and craters to choose from, but the Marius Lunar Pit has NASA's attention.
Inside the Conversation Between Magic's Sean Sweeney and Jon Gruden
Orlando Magic head coach Sean Sweeney and Super Bowl-winning coach Jon Gruden recently discussed numerous topics concerning the Magic.
Who are you rooting for in the World Series?
Four days after the Milwaukee Brewers finished off their sweep of the Dodgers in the National League Championship Series, the Tampa Bay Rays on Monday night won their American League Championship Series by dispatching the Cleveland Guardians in Game 6 at Tropicana Field. The Brewers last played in the Fall Classic in 1982, when they […]
Hemp business hoped to sell from home. What Lexington had to say
A resident applied to start a home business selling hemp products. Here’s what the Midlands town decided.
No science background? AI does the lab work
Financial analysts used Anthropic’s Claude to design protein minibinders that bound scorpion toxins in lab tests—showing AI can compress drug discovery...
Giants Cut Ties with Former Steelers RB Najee Harris
The New York Giants are releasing former Pittsburgh Steelers running back and first-round pick Najee Harris, per Ian Rapoport of […]
Moment of Science: New electric current test measures coffee quality without tasting
Getting a clue about the perfect brew! Here's how new research could make sure your morning pick-me-up is "not your average Joe". ☕
Jauan Jennings Trade: Raiders, Vikings Connected In Rumor
Jauan Jennings has not lived up to expectations with the Minnesota Vikings, and the team could part ways with the veteran receiver before the trade deadline. A seventh-round pick in the 2020 NFL Draft, the Tennessee product spent his early years in a supporting role before earning more snaps later in his career. He first …
WKTV Boo-ti-ful Costume Contest 2026
WKTV's Boo-ti-ful Costume Contest 2026 is inviting the community to submit their best kids and pets pictures for a chance to win prizes.
York County Mexican restaurant fails state health inspection
The state Department of Agriculture conducts annual inspections of food-serving businesses to ensure public safety and safe food-handling practices. Schools are inspected twice per year, according to the Bureau of Food Safety and Laboratories.
Yahoo Sports midseason awards: Biggest surprises, disappointments, Heisman picks, title predictions and more
Rush Oak Park parent looks for Endeavor Health merger
Rush University System for Health announced last week that it is planning to merge with Endeavor Health.
Voices: Jamey Taylor, Chief Information Officer, Dragonfly Health
This article is sponsored by Dragonfly Health. As hospice and post-acute care organizations look to reduce complexity across care delivery, technology is
John Turturro, thief of New York characters, adds a capstone in 'The Last Pickpocket in New York'
John Turturro grew up in Hollis, Queens, and has lived in Park Slope, Brooklyn, since 1988
Perceptions of science and scientists shape partisan views on common vaccines
How Americans view science and scientists is strongly associated with whether they think vaccines are safe and effective - and helps explain partisan differences in perceptions of some vaccines, according to a new study led by a team from the Annenberg Public Policy Center (APPC) of the University of Pennsylvania.
Looted French goods are popping up on resale site Vinted
The second-hand online marketplace Vinted has removed listings of looted French goods and stepped up checks on “suspicious” adverts, as the country’s authorities seek to prevent goods stolen during riots from being sold online.
Hampton Beach businesses want free trash pickup; residents say it’s time to pay
Should businesses pay for trash collection at Hampton Beach? A packed hearing showed a division between residents and business owners.
340 Home Care, Home Health, and Hospice Providers Earn Inaugural Trusted & Transparent™ Recognition from Accushield
/PRNewswire/ -- Accushield today announced the inaugural class of Trusted & Transparent™ home-based care companies, with 340 organizations and 883 location...
Bulls' Caleb Wilson Embracing Patience, Despite Glimpses of Stardom
Chicago's No. 4 overall pick is looking forward to his NBA regular season debut on Wednesday night.
Tacoma Dome eatery gets 60 red points. Here are Oct. 12 Pierce Co. food scores
Seven food establishments received 35 or more red points last week, which means they must be reinspected by the Health Department.
CA immigration business seized over allegations of practicing law without a license
The State Bar of California raided the North American Immigration Center in Chino, calling it an unauthorized law firm
How much longer will Sacramento’s progressive politics let Califia suffer?
“Cali is dying on the streets because there is no way...to help her.”
'DWTS' Dedication Night: What each couple will dance to Tuesday night
Dancing with the Stars returns Tuesday night, with the 10 remaining couples participating in the always emotional Dedication Night. The evening allows the celebrity dancers to perform for someone or something important to them, often featuring guest appearances.
Post-Shanghai ATP Power Rankings: Alexander Zverev Takes Charge
As you already know, this is not the ATP rankings list; rather, these are ATP power rankings that combine 2026 results, recent form, performance against elite opposition, current fitness, and the level each player is realistically capable of producing during the final stretch of the season. The picture has changed considerably since our pre-Wimbledon rankings. …
GM's core profit rises 22% on strength of pickup-truck business
GM shares fell about 6% in premarket trading.
'We used to go to the climate conferences together. We are not anymore': ESA official Simonetta Cheli tells us how the political landscape for Earth observation is changing
Live Science sat down with the European Space Agency's Simonetta Cheli to discuss the importance of Earth observation, how NASA budget cuts have changed the picture, and how the proliferation of private satellites could hinder our ability to view the planet.
GM’s core profit rises 22% on strength of pickup-truck business
By Kalea Hall Oct 20 (Reuters) - General Motors’ third-quarter results easily beat analyst expectations on the back of resolute shoppers who continue to spring for pricey pickups and SUVs. The company on Tuesday said quarterly earnings before interes...
GM's core profit rises 22% on strength of pickup-truck business
General Motors' third-quarter results easily beat analyst expectations on the back of resolute shoppers who continue to spring for pricey pickups and SUVs.
Green Bay Packers add former first-round pick amid defensive line injury concerns
The Green Bay Packers are searching for defensive line help after injuries weakened their options up front. With starting nose tackle Javon Hargrave out, veteran Chris McClellan is expected to fill the role, but Green Bay has limited depth behind him. To strengthen the rotation, the Packers have signed a former first round pick to [...]
Envelope Insiders Live: See stars of 'Furious,' 'Love Story' and more
The creatives behind 'Furious,' 'Love Story,' 'The Only Living Pickpocket in New York' and 'Tenzing' joined us for a day of food, wine and great conversations. Take a look inside.
Former campaign worker says she fended off advance by future NC insurance chief
The woman told FBI agents she quit Mike Causey’s campaign after he kissed her without provocation.
Bigfoot to Bojangles: How a Charlotte family built a business on make-believe
Long before the store became a Charlotte fixture, it started with a phone call, a rack of costumes and a couple willing to take a chance.
Pfizer makes ‘business decision’ to end phase 2 trial of autoimmune drug as program’s future uncertain
Pfizer has called time on a phase 2 trial of its CXCR5 antibody in an autoimmune blood disorder, with the company tight-lipped on whether this marks the end of the road for the asset. The Big Pharma had been evaluating the therapy, dubbed PF-06835375, in a phase 2 study of 61 patients with primary immune thrombocytopenia (ITP) that kicked off in 2022, according to the federal trials register. However, Pfizer confirmed to Fierce on Monday that this study had been terminated “due to a business decision.” “The decision to terminate the trial was not based on any safety concerns,” a spokesperson pointed out. At time of publication, PF-06835375 remained listed on Pfizer’s website for both ITP and lupus. A phase 1 study in lupus wrapped up in 2022, according to the trials database. ITP is an autoimmune disorder characterized by a low platelet count. Novartis was at one point evaluating its B-cell-depleting antibody ianalumab—recently approved as Fabhalta to treat immunoglobulin A nephropathy—as a potential treatment ITP. But the therapy struggled to demonstrate a benefit in the clinic for this indication. When contacted by Fierce, Pfizer wouldn’t confirm whether all work on PF-06835375 has been halted, and whether the company has any other plans to explore C-X-C chemokine receptor type 5 (CXCR5) as a mechanism. CXCR5 is found in blood cancers such as diffuse large B-cell lymphoma and mantle cell lymphoma chemokine receptor. However, there is little expression in normal tissue, which has led some drug developers to explore its potential. Vincerx Pharma had at one point been planning to take an anti-CXCR5 ADC into the clinic to treat B-cell malignancies, but that ambition was scrapped due to cash constraints. Where Big Pharma is placing its bets is one of the hot topics being discussed at Fierce Biotech's high-impact event in London next month. Find out more information and register by clicking on the banner below: [ ](https://qtxasset.com/quartz/qcloud5/media/image/where_big_pharma_is_placing_its_bets.png?VersionId=B8JrRbJ.pFUSK1pJgjeWHLGm_18RdLAy)
Franciscan Health Dyer adds OrderAhead food locker in partnership with Food Bank of NWI
Technology enhances partnership aimed at fighting Region food insecurity DYER, Ind. – Franciscan Health Dyer now has an OrderAhead food locker thanks to a partnership with the Food Bank of Northwest Indiana and generous donations to the Franciscan Health Foundation. The OrderAhead food locker program was designed by the Food Bank of Northwest Indiana for neighbors with chronic concerns about adequate food access. The lockers allow food-insecure individuals to place an order online for pickup at a scheduled time. “We are thankful to be able to further enhance our impactful partnership with the Food Bank with the addition of the
San Marcos High School breaks ground on a new era of health care education - Santa Barbara News-Press
The project has received significant philanthropic contributions, including $1.5 million from Cottage Health and $1 million from Betty Elings Wells