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Scientists Identify Atomic Trick That Keeps Gold Shiny
Gold’s characteristic glow famously doesn’t fade for thousands of years—and scientists have finally found the molecular trick that makes it so.
Omar Farha Receives Inaugural Reticular Science Prize
The honor is for major advances in the design, discovery, and application of molecularly defined materials.
Barcelona Institute for Global Health: Expanded TB screening does not speed up treatment initiation or improve survival in hospitalised patients with HIV
Adding molecular tests on sputum, urine and stool samples does not appear to outperform the standard WHO-recommended diagnostic approach.
The “impossible” LED that could change everything
Scientists at the University of Cambridge have achieved what was once considered impossible by electrically powering insulating nanoparticles to create a completely new kind of LED. Using tiny organic “molecular antennas,” the team found a way to funnel energy into materials that normally cannot conduct electricity, producing ultra pure near infrared light with remarkable efficiency.
Scientists Discover “Hidden” Materials That Could Transform Clean Energy and Batteries
Researchers have uncovered a hidden side of material formation by tracking what happens as specially designed molecules are heated.
Time matters: circadian genetics and the molecular logic of human health and disease
Nature Reviews Genetics - The circadian clock controls transcriptional and signalling networks across tissues to maintain homeostasis, with pathological consequences to its disruption. Kuo et al....
Protein reveals the oldest episode of sex and procreation among human species
Chinese scientists obtain the first molecular evidence of interbreeding between our ancestor ‘Homo erectus’ and the Denisovans, relatives of the Neanderthals
Scientists discover a weak spot shared by polio and common cold viruses
Scientists at the University of Maryland, Baltimore County, have uncovered a crucial trick used by enteroviruses—the group behind diseases like polio, myocarditis, encephalitis, and even the common cold—to reproduce inside human cells. The team captured, in unprecedented detail, how viral RNA recruits both viral and human proteins to assemble the machinery needed for replication, acting almost like a molecular “on-off switch” that controls whether the virus copies itself or makes proteins.
Scientists discover hidden fat-burning switch that could strengthen bones
Scientists at McGill University have uncovered a hidden molecular “switch” that turns on a powerful calorie-burning system in brown fat — the body’s heat-generating fat linked to metabolism and weight control. The breakthrough centers on glycerol, a molecule released when fat is broken down in the cold, which activates an enzyme called TNAP and triggers an alternative heat-producing pathway that scientists had struggled to explain for years.
Why coffee tastes bitter, according to molecular biology
Researchers imaged taste receptors responding to coffee compounds for the first time.
New method sharpens the search for alien biology
New UCR research shows that the search for life beyond Earth could benefit from a statistical approach that prioritizes patterns rather than searching for individual chemical or molecular traces.
Outstanding Seniors in the College of Science: Natalie Rawlings
The College of Science is proud to recognize 12 outstanding seniors who went above and beyond during their time as Wildcats. Natalie Rawlings is this semester's recipient from Molecular & Cellular Biology!
Scientists successfully transfer longevity gene and extend lifespan
Scientists at the University of Rochester pulled off a remarkable experiment: they transferred a longevity-related gene from the famously long-lived naked mole rat into mice, and the mice ended up healthier and lived longer. The special gene boosts production of a substance called high molecular weight hyaluronic acid, which appears to protect against cancer, reduce inflammation, and support healthier aging. The modified mice showed stronger resistance to tumors, healthier guts, and lower levels of age-related inflammation.
The National Academy of Sciences Elects Two Berkeley Lab Researchers
Two Lawrence Berkeley National Laboratory (Berkeley Lab) scientists have been elected to the National Academy of Sciences (NAS) in recognition of their distinguished and continuing achievements in original research. They are part of a cohort of 120 new members and 25 international members. The National Academy of Sciences is a private, nonprofit institution that was established under a congressional charter signed by President Abraham Lincoln in 1863. It recognizes achievement in science by election to membership, and — alongside the National Academy of Engineering and the National Academy of Medicine — provides science, engineering, and health policy advice to the federal government and other organizations. The 2026 electees bring the total number of active members to 2,705 with 557 international members. Gary Karpen is a biologist senior faculty scientist in Berkeley Lab’s Biological Systems and Engineering Division and a Professor of Cell and Developmental Physiology in the Department of Molecular and Cell Biology at UC Berkeley. Karpen studies how the structure, organization, and maintenance of genetic material impact inheritance and cell function. His lab focuses on chromatin — a packaged form of DNA strands wrapped around proteins that comprises our chromosomes — with a particular emphasis on centromeres, rarely expressed sequences called heterochromatin, DNA repair, and regulatory RNAs. His research reveals insights into fundamental aspects of nuclear organization and genome regulation that are shared across the tree of life, broadening our understanding of cancer and other diseases, birth defects, and aging. Kam-Biu Luk is a Professor Emeritus of physics at UC Berkeley and a retired senior faculty scientist in Berkeley Lab’s Physics Division. He is an experimental particle physicist whose research has focused on neutrinos: nearly massless, electrically neutral elementary particles that can pass through matter virtually undetected. Neutrinos are created during radioactive decay processes, including the fusion process occurring in stars and the fission process that powers nuclear reactors. Luk initiated and co-led the Daya Bay Reactor Neutrino Experiment, a project based in China with more than 200 international collaborators. In 2012, the Daya Bay experiment discovered a new form of a phenomenon called “neutrino oscillation” in which neutrinos change from one type to another. For this discovery, Luk and his collaborator Yifan Wang received the 2014 American Physical Society Division of Particles and Fields W.K.H. Panofsky Prize for outstanding work in experimental particle physics, and he was also the co-recipient of the 2016 Breakthrough Prize. Luk is currently participating in the Deep Underground Neutrino Experiment (DUNE) hosted by Fermi National Accelerator Laboratory, which will investigate any potential difference in behavior between neutrinos and antineutrinos that may shed light on the evolution of the universe, especially why antimatter is absent in the present universe. ### Lawrence Berkeley National Laboratory (Berkeley Lab) is committed to groundbreaking research focused on discovery science and solutions for abundant and reliable energy supplies. The lab’s expertise spans materials, chemistry, physics, biology, earth and environmental science, mathematics, and computing. Researchers from around the world rely on the lab’s world-class scientific facilities for their own pioneering research. Founded in 1931 on the belief that the biggest problems are best addressed by teams, Berkeley Lab and its scientists have been recognized with 17 Nobel Prizes. Berkeley Lab is a multiprogram national laboratory managed by the University of California for the U.S. Department of Energy’s Office of Science. DOE’s Office of Science is the single largest supporter of basic research in the physical sciences in the United States, and is working to address some of the most pressing challenges of our time. For more information, please visit energy.gov/science.
URI Researcher Examines How AI Is Changing the Language of Science
From philosophy conferences to biomedical research, URI Assistant Professor of Cell and Molecular Biology Nic Fisk is examining how computational tools are changing how scientists talk about their research – and what the consequences might be.
4D mammo may be up to four times more accurate than 3D
The 4D system harnesses X-ray diffraction to measure molecular-level signatures of disease; these tissue “fingerprints” could help providers diagnose breast cancer in its earliest stages.
First-ever 3D view shows how killer T cells destroy cancer
The body’s “killer” T cells don’t just attack—they strike with astonishing precision, forming a tiny, highly organized contact zone that lets them destroy dangerous cells without harming their neighbors. Now, scientists have captured this process in unprecedented detail, revealing a hidden world of molecular choreography.
RM Science Bowl triumphs with most successful season in recent history
Someone slams the buzzer, but the molecular biology question has only been half-read. With just enough confidence to risk it all, they answer, knowing that it could make the difference between winning and losing the match. Science Bowl is a fast paced competition for high schoolers sponsored by the Department of Energy that tests students’...
Seven UC Berkeley faculty elected to the American Academy of Arts and
This week, seven UC Berkeley faculty — representing academic fields from philosophy to molecular biology to engineering — were named members of the American Academy of Arts and Sciences. The Academy,
10x Science: $4.8 Million Raised To Build AI Platform For Molecular Protein Characterization
10x Science, an artificial intelligence company focused on molecular-level protein characterization, announced that it has raised $4.8 million in seed funding led by Initialized Capital, with participation from Y Combinator, Civilization Ventures, Founder Factor, and a group of strategic angel investors. The round was oversubscribed and will support the company’s efforts to scale its platform and expand partnerships across the life sciences ecosystem.
Harvard scientists link gut bacteria to depression through hidden inflammation trigger
A gut bacterium may be quietly fueling depression through an unexpected chemical twist. Researchers found that when Morganella morganii interacts with a common pollutant, it produces a molecule that triggers inflammation—something strongly linked to depression. This finding helps explain how gut microbes can influence brain health at a molecular level. It also raises the possibility of new treatments that target the immune system rather than just the brain.
Rediscovered after 100 years: scientists reveal status of the critically endangered Osmanthus pubipedicellatus
Integrative morphological and molecular evidence confirms the rediscovery of a long-lost Osmanthus species, revealing its declining population and urgent conservation needs.
Twisted nanoparticles sorted by light
Chiral objects are important in fields like drug development because their interactions with biological systems depend on handedness. Researchers from Tokyo University of Science, Institute for Molecular Science, and Seoul National University used light to selectively manipulate nanosized chiral objects. By confining circularly polarized light in an ultra-thin optical fiber, they transported metallic chiral nanoparticles based on handedness, thereby enabling chirality control at near-molecular scales, opening possibilities for applications involving chiral systems, including drug development.
Scientists stunned as bacteria rewire DNA machinery to shape cells
Cyanobacteria—ancient microbes that oxygenated Earth and made complex life possible—are still revealing surprises billions of years later. Scientists have now discovered that a molecular system once used to separate DNA has been repurposed into something entirely different: a structure that shapes the cell itself.
Hot ticket: Rodeo kicks off and Fleet Week takes flight
Pretty Fly for a Smart Guy: Dexter Holland, lead singer of The Offspring and a molecular biologist, will headline an upcoming installment of Space Center Houston‘s Thought Leader Series.
Scientists develop 'light switch' for the love hormone
Researchers have developed a molecular "light switch" for the so-called love hormone oxytocin, offering new insights into how social behavior, partnership bonding, emotions, and mental health are wired ...
Simon Cherry Receives ESMI Award for Significant, Long-Term Contributions to Imaging Science
The Distinguished Research Professor of biomedical engineering has received the 2026 ESMI Award from the European Society for Molecular Imaging. Among the most prestigious honors in imaging science, the award celebrates a researcher for their outstanding contributions to the interdisciplinary field.
Scientists Unveil Microscopy Breakthrough That Reveals “Invisible” Molecular States
Scientists have introduced a microscopy technique that reveals a hidden layer of chemistry involving molecules that normally evade detection.
Life on Mars? Tiny cells just survived shock waves and toxic soil
Mars may be hostile, but it might not be entirely unlivable. In lab experiments, yeast cells survived simulated Martian shock waves and toxic perchlorate salts—two major environmental threats on the Red Planet. Their secret weapon was forming protective molecular clusters that shield critical cellular functions under stress. Without these defenses, survival plummeted, pointing to a potential universal strategy life could use beyond Earth.
Kansas City health leaders announce new integrated theranostics research and treatment center
The center will unite diagnostics, molecular imaging, radiopharmaceutical production and targeted therapies under one coordinated platform.
Experts set 2030 nutrition science goals for resilient food systems
As the second quarter of the 21st century unfolds, experts are examining the state of nutrition as the UN Sustainable Development Goals (SDG) deadline looms with five years remaining. To achieve these targets, a new paper outlines key goals for nutrition science from 2025 to 2030. The Frontiers in Nutrition publication discusses the interconnectedness between nutrition, food security, and sustainability in complex food systems affected by shocks, policies, and environmental limits. The researchers reveal how these modern factors impact nutrition science and shape research agendas.
Science history: Doctor hypothesizes that 'transmissible proteins' can cause disease, contradicting a 'central dogma' of molecular biology
Prion diseases, such as "mad cow," are caused by transmissible proteins that were identified in the 1980s.
Scientists just uncovered the secret behind nature’s “proton highway”
Scientists have zoomed in on how phosphoric acid moves electrical charges so efficiently in both biology and technology. By freezing a key molecular pair to extremely low temperatures, they found it forms just one stable structure—contrary to predictions. This structure relies on a specific hydrogen-bond network that may be universal in similar systems. The discovery helps explain how protons travel so quickly and could inspire better energy materials.
4 NYU faculty honored for STEM research by American Association for the Advancement of Science
Four NYU faculty members were recognized for their research in areas of biology, neuroscience and chemical and biomolecular engineering as fellows of the American Association for the Advancement of Science. The AAAS — which aims to shape science policy and build a community for STEM researchers — elected 449 researchers across the United States for...
A Forecast of What’s Next for Chemical Engineering and Materials Science - USC Viterbi
The 20th annual Student Symposium and Showcase at the USC Viterbi Mork Family Department of Chemical Engineering & Materials Science highlights research in AI-driven materials discovery, energy transition and biomolecular engineering.
Scientists Build Five-in-One “Super Molecule” for Next-Gen Electronics
A hybrid synthesis strategy enables complex molecular architectures to function as a single electronic system.
Helen H. Hobbs, M.D., honored for innovation in cardiovascular science
Helen H. Hobbs, M.D., Professor in the Eugene McDermott Center for Human Growth and Development and of Internal Medicine and Molecular Genetics at UT Southwestern Medical Center, has been named the recipient of the 2026 Valentin Fuster Award for Innovation in Science by the American College of Cardiology (ACC).
A newly-discovered molecular process explains how our bodies perceive the cold
Research by Nobel laureate David Julius has captured how the TRPM8 protein changes when exposed to low temperatures, opening a new avenue for treating cold-induced pain
AstroSara – training with Spain’s first female astronaut
In Spain she’s a media star. Known as AstroSara on YouTube, Sara García Alonso is a science communicator, author, molecular biologist – and future ESA reserve astronaut. We accompany her as she prepares for the job.
Two Salk scientists elected as 2025 AAAS Fellows - Salk Institute for Biological Studies
Highlights Salk scientists Gerald Shadel and Tatyana Sharpee elected as American Association for the Advancement of Science (AAAS) 2025 Fellows AAAS Fellows are distinguished scientists, engineers, and innovators who have made significant contributions to their fields LA JOLLA—Salk molecular biologist Gerald Shadel, PhD, and neuroscientist Tatyana Sharpee, PhD, have been elected as American Association for the Advancement of Science (AAAS) 2025 Fellows. The honor recognizes scientists with distinguished scientific and social accomplishments, and AAAS Fellows become national and global science spokespersons for the rest of their lives.
Scientists Call for a Complete Rethink of Alzheimer’s Treatment
New insights suggest that Alzheimer’s cannot be tackled through a single pathway, as its roots extend across molecular, genetic, and systemic processes.
WHO recommends new diagnostic tools to help end TB
On World TB Day, the World Health Organization (WHO) is urging countries to accelerate action to end tuberculosis (TB) and expand access to lifesaving services by using new innovations such as diagnostic tests that can be used near the point-of-care and tongue swabs that can help detect the disease faster reaching more people.
The surprising new ways bacteria spread without propellers
Scientists at Arizona State University have uncovered surprising new ways bacteria move, even without their usual whip-like propellers called flagella. In one study, E. coli and salmonella were found to spread across moist surfaces by fermenting sugars and creating tiny fluid currents that carry them forward — a newly identified behavior researchers call “swashing.” In another study, a different group of bacteria was shown to control its movement using a microscopic molecular “gearbox” that can reverse direction like a biological snowmobile.
Biomolecular profiling for noninvasive health monitoring
Nature Biotechnology - Kim et al. present mass spectrometry and wearable sensor technology as complementary approaches that, when integrated, can co-evolve to open new possibilities for noninvasive...
Scientists discover tiny plant trick that could supercharge crop yields
Researchers have uncovered a molecular trick used by hornwort plants that could help future crops capture carbon dioxide more efficiently. A unique protein feature called RbcS-STAR causes the key photosynthesis enzyme Rubisco to cluster into dense compartments, helping it work more effectively. When scientists added this feature to other plants, Rubisco reorganized in the same way. The finding raises the possibility of engineering more efficient photosynthesis into major crops.
Choreographing molecular design with TANGO
Nature Computational Science - A reward function (TANGO) is developed to enforce building blocks in generative artificial intelligence and leverage the synthesizability of high-value materials.
Stanford Scientists Uncover the Molecular Mistake That May Trigger Brain Aging
Scientists have identified a critical breakdown in the cellular machinery that produces proteins in aging brains.
Scientists discover a brain signal that may trigger autism’s domino effect
Researchers have uncovered a surprising molecular chain reaction in the brain that may play a role in some forms of autism. The study suggests that nitric oxide, a tiny signaling molecule normally involved in fine-tuning communication between brain cells, can sometimes trigger a cascade of changes inside neurons. When nitric oxide activity rises, it can alter a protective protein called TSC2, weakening an important cellular brake and allowing the mTOR pathway, which controls growth and protein production, to become overactive.
Scientists Spin Molecules Inside a Frictionless Superfluid for the First Time
A newly designed optical centrifuge allows scientists to control molecular rotation inside superfluid helium nano-droplets. Physicists have developed a new version of an optical centrifuge that can control how molecules rotate while they are suspended inside liquid helium nano-droplets. The advan
Electrons catapult across solar materials in just 18 femtoseconds
Electrons in solar materials can be launched across molecules almost as fast as nature allows, thanks to tiny atomic vibrations acting like a “molecular catapult.” In experiments lasting just 18 femtoseconds, researchers at the University of Cambridge observed electrons blasting across a boundary in a single burst, far faster than long-standing theories predicted. Instead of slow, random movement, the electron rides the natural vibrations of the molecule itself, challenging decades of design rules for solar materials.
(Half) Twisted Science: Researchers Build a Molecular Möbius Strip With Only Half the Twist
The Quantum Insider (TQI) is the leading online resource dedicated exclusively to Quantum Computing.
'THE STORY OF EVERYTHING' PRESENTS GROUNDBREAKING EVIDENCE THAT HAS REIGNITED THE DEBATE OVER SCIENCE, ORIGINS, AND THE EXISTENCE OF GOD IN THEATRES NATIONWIDE FROM FATHOM ENTERTAINMENT APRIL 30-MAY 6
A new feature documentary is about to challenge everything you thought science had settled about the origin of the universe—and the existence of God. The Story of Everything arrives in theatres nationwide April 30–May 6 from Fathom Entertainment, the leading specialty distributor of content to theatrical partners worldwide. The Story of Everything will bring to the big screen stunning new evidence from cosmology, physics, and molecular biology that its creators say demands a radical rethinking o
Scientists find the genetic switch that makes pancreatic cancer resist chemotherapy
Scientists have identified a crucial molecular switch that decides whether pancreatic cancer cells resist chemotherapy or respond to it. The key player, a gene called GATA6, keeps tumours in a more structured and treatable form—but it gets shut down by an overactive KRAS-driven pathway. When researchers blocked that pathway, GATA6 levels rebounded and cancer cells became more sensitive to chemo. The discovery could help turn some of the toughest pancreatic tumours into ones doctors can better control.
The science behind exercise and why it's good for our bodies
This will come as a surprise to no one, but exercise is really good for us. But why it works and how it works are far less understood. Horizons moderator William Brangham explores that with Stanford University’s Euan Ashley. He's a professor of genomics and cardiovascular medicine and is part of a team trying to understand, at the very molecular level, how exercise changes our bodies, and why.
The science behind exercise and why it's good for our bodies
This will come as a surprise to no one, but exercise is really good for us. But why it works and how it works are far less understood. Horizons moderator William Brangham explores that with Stanford University’s Euan Ashley. He's a professor of genomics and cardiovascular medicine and is part of a team trying to understand, at the very molecular level, how exercise changes our bodies, and why.
Five Berkeley Lab Scientists Receive DOE Early Career Research Awards
Five scientists from Lawrence Berkeley National Laboratory (Berkeley Lab) have received Early Career Research Program (ECRP) awards from the Department of Energy. The ECRP program, now in its 16th year, was established to bolster the nation’s scientific workforce by supporting exceptional researchers at the outset of their careers, when many scientists do their most formative work. Recipients use the funding to pursue projects that have the potential to solve scientific challenges and advance the country’s STEM capabilities. To be eligible for the program, a researcher must be an untenured, tenure-track assistant or associate professor at a U.S. academic institution, or a full-time employee at a DOE national laboratory or Office of Science user facility, who is within 10 years of having earned their doctorate. Awards to an institution of higher education will be approximately $875,000 over five years, and awards to a DOE national laboratory or Office of Science user facility will be approximately $2,750,000 over five years. This year’s Berkeley Lab awardees and their projects are listed below: Timon Heim: Better detectors for more powerful particle colliders Timon Heim is a staff scientist in the Physics Division. His ECRP project will develop a new type of detector that can track the particles generated by collisions in particle colliders with high spatial and temporal resolution. Current detectors in use at high-energy colliders, like the ATLAS detector at the Large Hadron Collider (LHC) at CERN, can track the trajectory and measure momentum of particles, but they can’t track a particle’s time of arrival with sufficient precision to discern from which of the many particle interactions they originate. Heim’s proposed technology — called a 4D tracking detector, because it captures data about particles’ positions in space and time — aims to solve this challenge, allowing researchers to glean more precise data from collision experiments to uncover new insights into fundamental forces and potentially discover new particles. The enhanced capabilities of 4D detectors will be a necessity for experiments at future colliders, such as the Muon Collider or Future Circular Collider. The project will develop custom microelectronics that process the signal of a pixelated silicon sensor that can register charged particles passing through it in an extreme radiation environment that these colliders produce during operation. The goal is to measure individual particles’ position with 50-micro-meter spatial and 50 pico-second (one trillionth of a second) temporal precision, for an incoming flux of around 1 billion particles per second per square centimeter. Harrison Lisabeth: Studying underground processes to unleash abundant energy Harrison Lisabeth is a research scientist in the Energy Geoscience Division focused on combining real-world experiments and AI to guide development of geothermal energy systems. His project will explore how deep underground rock formations – where geothermal wells are dug – are stressed by chemical reactions of the minerals and mechanical strain from movements in the Earth. A better understanding of subsurface stresses is essential to engineer safe and reliable geothermal wells that access the heat of deep rocks to produce electricity. It is estimated that the U.S. could generate ten times the amount of energy needed to power the grid using geothermal sources. Lisabeth plans to simulate how minerals grow, dissolve, and influence the behavior of surrounding rock in geothermal reservoirs by tracking chemical changes in rock samples under pressure in the lab. The project will also develop machine learning models to predict geologic strain based on field measurements and refine existing models that describe how common rock types deform under stress. Combining these approaches, Lisabeth hopes to develop a framework to predict stress to improve stability and longevity of geothermal wells. Daniel Carney: Pushing the quantum boundaries of particle measurement Daniel Carney is a staff scientist in the Physics Division who uses quantum information science to study particle physics and gravity. At very small scales, “quantum noise” — random fluctuations from the act of measurement — can drown out faint signals from rare processes. Carney’s ECRP project, “Fundamental Physics at the Quantum Limits of Measurement,” aims to build a new mechanical quantum sensor that can measure extremely small particle interactions below the limits of that quantum noise. The approach uses lasers to hold a tiny bead containing radioactive atoms; when one decays, the system measures the bead’s motion and the energy of any particles emitted. The experiment’s initial goal is to search for heavy sterile neutrinos, hypothetical particles predicted by some extensions of the Standard Model. The system could also help measure the mass of the neutrino, study the way particles interact through the electromagnetic and weak forces, and hunt for low-mass dark matter — all unsolved mysteries in particle physics. Callum Wilkinson: Using machine learning to demystify neutrinos Callum Wilkinson is a staff scientist in the Physics Division and part of the international Deep Underground Neutrino Experiment (DUNE) hosted by Fermi National Accelerator Laboratory. DUNE will create an intense beam of neutrinos that interact in detectors in Illinois and, after an 800-mile journey through the earth, in massive detectors in South Dakota. By precisely measuring neutrinos and how they change, researchers will get a better understanding of their fundamental properties and whether they are responsible for why there is so much more matter than antimatter in our universe. Wilkinson’s ECRP project will apply two machine learning techniques to improve the analysis of DUNE’s data and enhance the experiment’s precision. One approach will look for hidden patterns in how neutrinos interact and produce low-energy particles, while the other will help correct for distortions in what the detectors record. The methods will be tested on one of DUNE’s prototype detectors and could be used in other neutrino experiments, improving their measurements and helping scientists build better models. Aditi Krishnapriyan: Machine learning methods that scale as datasets grow Aditi Krishnapriyan is a faculty scientist in Berkeley Lab’s Applied Mathematics and Computational Research Division (AMCR) and assistant professor at UC Berkeley. Her project, awarded through UC Berkeley, will develop machine learning methods that scale with dataset size for modeling complex, multi-scale phenomena. The resulting tools can be applied in a wide range of research, including the study of new electrolytes for batteries or the examination of molecular interactions. ### Lawrence Berkeley National Laboratory (Berkeley Lab) is committed to groundbreaking research focused on discovery science and solutions for abundant and reliable energy supplies. The lab’s expertise spans materials, chemistry, physics, biology, earth and environmental science, mathematics, and computing. Researchers from around the world rely on the lab’s world-class scientific facilities for their own pioneering research. Founded in 1931 on the belief that the biggest problems are best addressed by teams, Berkeley Lab and its scientists have been recognized with 17 Nobel Prizes. Berkeley Lab is a multiprogram national laboratory managed by the University of California for the U.S. Department of Energy’s Office of Science. DOE’s Office of Science is the single largest supporter of basic research in the physical sciences in the United States, and is working to address some of the most pressing challenges of our time. For more information, please visit energy.gov/science.
Meet our new faculty: Pini Perera
Pini Perera’s work bridges molecular biology and toxicology to uncover the mechanisms behind environmental impacts on health.
Mysterious RNA led scientists to a hidden layer of cancer
A mysterious RNA found in breast cancer led scientists to uncover an entire hidden class of cancer-specific RNAs across dozens of tumor types. These molecules form unique molecular signatures that identify cancer type and subtype with remarkable accuracy. Some even drive tumor growth and metastasis. Because many are released into the bloodstream, a simple blood test can track how patients respond to treatment and predict survival.
This breakthrough could finally unlock male birth control
Scientists at Michigan State University have uncovered the molecular “switch” that powers sperm for their final, high-speed dash toward an egg. By tracking how sperm use glucose as fuel, the team discovered how dormant cells suddenly flip into overdrive, burning energy in a carefully controlled, multi-step process. A key enzyme, aldolase, helps convert sugar into the burst of power needed for fertilization, while other enzymes act like traffic controllers directing the flow of fuel.
Young scientists from across the UK shortlisted for largest unrestricted science prize
The Blavatnik Awards for Young Scientists today announced the Finalists for the 2026 Blavatnik Awards for Young Scientists in the United Kingdom. The Awards recognise scientific advances by UK researchers across Life Sciences, Chemical Sciences, and Physical Sciences & Engineering. Now in its ninth year, each Blavatnik Awards Laureate will receive an unrestricted £100,000 (US$135,000) prize, while the remaining six Finalists will be awarded £30,000 (US$40,400) each. This year’s Finalists include: Chemical Sciences Finalists Michael J. Booth, PhD – University College London (UCL) Mathew H. Horrocks, PhD – The University of Edinburgh Maxie M. Roessler, DPhil – Imperial College London Life Sciences Finalists Nicholas R. Casewell, PhD – Liverpool School of Tropical Medicine Thi Hoang Duong (Kelly) Nguyen, PhD – MRC Laboratory of Molecular Biology Pontus Skoglund, PhD – The Francis Crick Institute Physical Sciences & Engineering Finalists Radha Boya, PhD – The University of Manchester Paola Pinilla, PhD – University College London (UCL) Iestyn Woolway, PhD – Bangor University
This tiny molecular trick makes spider silk almost unbreakable
Scientists have cracked a key mystery behind spider silk’s legendary strength and flexibility. They discovered that tiny molecular interactions act like natural glue, holding silk proteins together as they transform from liquid into incredibly tough fibers. This same process helps create silk that’s stronger than steel by weight and tougher than Kevlar.
Scientists finally explain statin muscle pain
Statins are a cornerstone of heart health, but muscle pain and weakness cause many patients to quit taking them. Scientists have now identified the precise molecular trigger behind these side effects. They found that statins jam open a critical muscle protein, causing a toxic calcium leak. The discovery could lead to safer statins that keep their life-saving benefits without the muscle damage.
Electric fields flip the rules of water chemistry
nside electrochemical devices, strong electric fields dramatically alter how water molecules behave. New research shows that these fields speed up water dissociation not by lowering energy costs, but by increasing molecular disorder once ions form. The reaction becomes entropy-driven—exactly the opposite of what happens in ordinary water. The findings also reveal that intense fields can push water from neutral to highly acidic, with major implications for hydrogen production.
HIV: A Treatment Triumph Still Searching For Basic Science Answers
Molly Ohainle was growing up in the Bay Area when the AIDS crisis hit. She lost both of her uncles to HIV. Now, she researches HIV as a professor of immunology and molecular medicine at UC
Scientists use AI to crack the code of nature’s most complex patterns 1,000x faster
Order doesn’t always form perfectly—and those imperfections can be surprisingly powerful. In materials like liquid crystals, tiny “defects” emerge when symmetry breaks, shaping everything from cosmic structures to everyday technologies. Now, researchers have developed an AI-powered method that can predict how these defects will form and evolve in milliseconds instead of hours. By learning directly from data, the system accurately maps molecular alignments and complex defect behavior, even in situations where defects merge or split.
This discovery could let bones benefit from exercise without moving
Researchers have discovered a biological switch that explains why movement keeps bones strong. The protein senses physical activity and pushes bone marrow stem cells to build bone instead of storing fat, slowing age-related bone loss. By targeting this “exercise sensor,” scientists believe they could create drugs that mimic exercise at the molecular level. The approach could protect fragile bones in people who are unable to stay active.
Alzheimer’s may trick the brain into erasing its own memories
Alzheimer’s may destroy memory by flipping a single molecular switch that tells neurons to prune their own connections. Researchers found that both amyloid beta and inflammation converge on the same receptor, triggering synapse loss. Surprisingly, neurons aren’t passive victims—they actively respond to these signals. Targeting this receptor could offer a new way to protect memory beyond current amyloid-focused drugs.
Welcome to post-Darwinism: AI fires silver bullet for creating new life
In a breakthrough experiment, molecular biologists and tech entrepreneurs have teamed up to write the genetic code of a virus that destroys killer bacteria
Scientists destroy 99% of cancer cells in the lab using “vibrating molecules” - Futura-Sciences
A groundbreaking advance in the fight against cancer has just been made. Scientists have developed a revolutionary technique that uses vibrating molecules to kill malignant cells. This innovative method showed a remarkable 99 percent success ... Read more
Scientists Discover a Hidden RNA “Aging Clock” in Human Sperm
The molecular contents of sperm go through similar shifts over time in both mice and humans, which may lead to a rapid, dramatic shift at mid-life.
Hubble Observes Stars Flaring to Life in Orion
This Hubble image features just-forming stars, called protostars, dazzle a cloudy landscape in the Orion Molecular Cloud complex.
Tempus and NYU Langone Health Announce Strategic Collaboration to Advance Precision Oncology
CHICAGO, January 12, 2026--Tempus, a leader in artificial intelligence and precision medicine, and NYU Langone Health, one of the nation’s premier academic medical centers, today announced a multi-year strategic collaboration aimed at transforming cancer care through advanced molecular profiling and data-driven insights. The collaboration will support NYU Langone Health’s Center for Molecular Oncology at the Laura and Isaac Perlmutter Cancer Center, a comprehensive, pan-cancer initiative to more
MSU-DOE Plant Research Laboratory celebrates 60 years
The Plant Research Laboratory's mission is to study and understand how photosynthetic organisms work on the molecular level, to ultimately develop technologies that improve human lives.
This CRISPR breakthrough turns genes on without cutting DNA
A new CRISPR breakthrough shows scientists can turn genes back on without cutting DNA, by removing chemical tags that act like molecular anchors. The work confirms these tags actively silence genes, settling a long-running scientific debate. This gentler form of gene editing could offer a safer way to treat Sickle Cell disease by reactivating a fetal blood gene. Researchers say it opens the door to powerful therapies with fewer unintended side effects.
A missing flash of light revealed a molecular secret
Scientists have found a way to see ultrafast molecular interactions inside liquids using an extreme laser technique once thought impossible for fluids. When they mixed nearly identical chemicals, one combination behaved strangely—producing less light and erasing a single harmonic signal altogether. Simulations revealed that a subtle molecular “handshake” was interfering with electron motion. The discovery shows that liquids can briefly organize in ways that dramatically change how electrons behave.
Scientists Discover How the Uterus “Feels” Its Way Through Childbirth
Molecular discoveries may help improve treatments for labor and pain. When labor starts, the uterus must produce steady, precisely timed contractions to allow a safe delivery. Hormones such as progesterone and oxytocin are known to drive this process, but researchers have long believed that physi
Beyond silicon: These shape-shifting molecules could be the future of AI hardware
Scientists have developed molecular devices that can switch roles, behaving as memory, logic, or learning elements within the same structure. The breakthrough comes from precise chemical design that lets electrons and ions reorganize dynamically. Unlike conventional electronics, these devices do not just imitate intelligence but physically encode it. This approach could reshape how future AI hardware is built.
The science of staying strong
Muscles power every movement, but they also tell the story of aging itself. Scientists are uncovering how strength fades, why some species resist it and what lifestyle and molecular clues could help preserve muscle health for life.
Your body feels cold in two different ways
Researchers have uncovered that the body uses different molecular systems to sense cold in the skin versus internal organs. This explains why surface chills feel very different from cold experienced deep inside the body.
UT Southwestern biochemist to receive O’Donnell Award from TAMEST
Yunsun Nam, Ph.D., Professor of Biochemistry and Biophysics at UT Southwestern Medical Center, will receive the 2026 Edith and Peter O’Donnell Award in Biological Sciences from the Texas Academy of Medicine, Engineering, Science & Technology (TAMEST) for her research into how RNAs and proteins interact at the molecular level. Her work has shed light on gene regulation, cancer biology, and RNA-based therapeutics.
Scientists capture most detailed look inside DNA droplets
High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact within these droplet-like structures. The findings connect molecular architecture to the broader behaviors of these droplets in cells.
Earth’s early oceans hid the secret rise of complex life
Scientists have discovered that complex life began evolving much earlier than traditional models suggested. Using an expanded molecular clock approach, the team showed that crucial cellular features emerged in ancient anoxic oceans long before oxygen became a major part of Earth’s atmosphere. Their results indicate that early complexity developed slowly over an unexpectedly long timescale.
Cities put science in the spotlight
When three European cities launch an initiative next year to boost scientific excellence and collaboration, much of the action is likely to take place in public spaces rather than in the laboratory.That is welcome news for Ana Marušić. A medical doctor and professor at the University of Split Medical School in Croatia, Marušić champions close connections between “town and gown” to encourage citizen involvement in research, raise public health awareness and ignite young people’s interest in science. “Responsible research and innovation cannot be done in an ivory tower, answering only the questions that are relevant for scientists,” explains Marušić, who chairs the Department of Research in Biomedicine and Health and leads the Centre for Evidence-based Medicine. “The role of the university is to be a medium for transferring new discoveries in science to society, but also to listen to society about what is important and what is needed.”Three cities united by scienceMarušić’s efforts stand to gain traction through Science Comes to Town (SCTT), a new European project to highlight science’s role in society and strengthen cross-border collaboration in research, innovation and sustainability. With funding from the European Commission, three cities—Split, Brest (in France) and Kiel (in Germany)—plan more than 1,000 public events, workshops and competitions for citizens of all ages, researchers, businesses and policymakers. The year-long project kicks off in Spilt on 20 January with a conference involving partner institutions, community representatives and European policymakers. The three cities may be geographically far apart, but they share much in common. All are located on coasts and are home to top regional research institutions that are part of SCTT. Among the project's partners, the University of Western Brittany in Brest, Kiel University and the University of Split belong to the SEA-EU university alliance, uniting nine European coastal academic institutions to advance research, student exchanges and sustainable development. “These universities have a very strong connection between gown and town,” explains Marušić, who is one of Split’s SCTT ambassadors. “It's very important that these universities are there for the community so that we can learn from each other and grow together.”Tackling Europe’s STEM shortagesSCTT will also reinforce efforts to address Europe’s widening gap in science, technology, engineering and mathematics (STEM) education. Studies show that nearly eight out of ten small- and medium-sized businesses cannot find enough workers with the skills required in advanced computing and artificial intelligence (AI)—hindering initiatives to boost European innovation and competitiveness. In healthcare, the European Commission has estimated a shortfall in medical professionals of 1.2 million, due to fewer young people joining the field and an ageing population that needs more care.Strengthening knowledge and dialogue can also help build trust between scientists and the public at time when disruptive technologies are reshaping research and clinical practice, but are also sparking questions about ethics and accuracy. With experience in the classroom and in clinical epidemiology—a discipline involving monitoring and controlling public health problems—Marušić sees the potential risks of over-reliance on AI and chatbot answers for both research and learning. “AI is a very good tool, but one has to be very critical about it,” she adds. “Delegating brain activities will definitely diminish your neural capacities because you are not developing the circuitry that is important for higher-level cognitive engagement.” She stresses the importance of critical thinking and encourages students to use AI as a researcher’s tool to reinforce rather than supplant human discretion and brainpower.The power of outreachSplit’s experience in bringing scientists and the public together has provided a platform for discussing research ethics and explaining science in simple terms. Local efforts to expand health literacy and awareness have helped reduce cardiovascular disease among women, according to Marušić’s research. The city’s university also hosts events to introduce schoolchildren to science, using hands-on experiments to spark curiosity.Marušić’s own love of science began with an interest in studying molecular biology. “But my parents told me, why don't you study medicine?” she recalls. “I said, OK, why not? And that was the best decision that I made.” Marušić is not a practicing physician, but teaches anatomy and public health. She also co-edits ST-OPEN, an overlay university journal that works on capacity building for research publishing among students and their supervisors. Balancing teaching, research and editorial work, she is a strong advocate for medical studies, urging high school students to consider medicine “because later on it gives you a really wide perspective about human life and about society” as well as many career opportunities.As SCTT prepares to bring science into daily life in 2026, Marušić hopes that it will build permanent bridges between scientists and citizens across Europe. “We can be a showcase for making collaboration with the community stronger to share knowledge, attract young talent and integrate critical and scientific thinking into everyday life,” she explains, adding that "collaborating with businesses to improve cities and communities is also an important aspect of this project."Science|Business, which connects policymakers, academics and industry through its news reporting, analysis and events, is an SCTT partner.
The Sunshine Hormone’s Second Act: Why Science is Rethinking Vitamin D
New research reclassifies Vitamin D from a bone-health nutrient to a systemic steroid hormone, challenging public health guidelines. This deep dive explores the conflict between clinical trials and molecular biology, the potential for cancer and autoimmune prevention, and the future of personalized supplementation based on genetic metabolism.