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Cruz Foam had a promising idea. Why couldn’t it make its sustainable packaging business work?
Cruz Foam's biodegradable packing material made from shrimp shells and food waste attracted wide attention and big-name investors, but the Santa Cruz-based company has closed up shop after what one former exec says were struggles to solve the full range of problems its customers needed packaging to address.
Nancy Pelosi isn't sitting out the fight to replace her
The San Francisco lawmaker has dived into the intraparty fight to succeed her in Congress. Is it personal, or her prerogative to have a say in her replacement?
Duke Endowment makes big investment in NC Children’s hospital
By Anne Blythe Key Takeaways: On a heavily wooded tract near the intersection of U.S. 1 and N.C. 540 — a 220-acre spot in southern Apex so void of infrastructure it shows up only as GPS coordinates on a map, the Duke Endowment announced a transformative $100 million grant Tuesday morning. The investment will help […]
Australian Politician Who Was Hit by Car Has Lost Both Legs
MELBOURNE, Australia (AP) — Doctors have amputated both of Australian federal lawmaker Helen Haines ' legs as she remains in critical condition after being repeatedly hit by a car in an apparent act of political violence, her husband said Wednesday. The 65-year-old independent politician is ...
Billionaire Mark Cuban’s 5-step plan to make healthcare affordable targets drug middlemen’s ‘contractual terrorism’
The Cost Plus Drugs cofounder told Texas lawmakers that insured patients are often better off paying cash—and laid out five fixes built around price transparency.
Amodei says Anthropic must stay in 'race to the top' to keep AI safe
Amodei said Anthropic would be best placed to make AI safe by staying at the top of the game.
Beyond the ballot, block walking brings politics to the doorstep
“What makes a difference is neighbors showing up at their neighbors' doorstep and telling them why this election is so important,” Democratic Senate candidate James Talarico said.
TWICE’s Jihyo Departs JYP Entertainment After 21 Years + Launches New Agency EMITHAUS
Jihyo is beginning a journey with a new company! On October 21, the TWICE member took to her Instagram to share the following handwritten letter: Hello, this is Jihyo. I’m writing today because there’s something I’d like to share with you. After 21 years, my journey with JYP Entertainment, which began when I was just a child, has come to an end. Trying to put 21 years into just a few words is harder than I thought it would be.From childhood through my teenage years and into adulthood, I’ve spent most of my life at JYP.There were good days and difficult ones, but one thing I know for certain is that every one of those moments has shaped who I am today.I want to express my sincere gratitude to everyone at JYP who has been by my side and helped me grow over the years.I will always cherish the time we shared and the memories we made together. To me, independence is not so much a conclusion about the time that has passed, but a choice about how I want to live going forward.As the first step in this new chapter, I have established my own company, EMITHAUS.Just as “EMIT” means to “express or release,” I hope this will be a place where I can freely explore and bring to life even the possibilities within me that I have yet to discover.As I step away from a familiar environment and begin working in new ways, I will approach every decision and every endeavor with even greater thoughtfulness and responsibility. I also want to make it clear that this decision does not mean saying goodbye to the team I’ve been part of for so long.TWICE is an irreplaceable part of my life.Just as I cherish all the years we’ve shared, I look forward to all the moments still ahead of us.I will continue to stand on stage with my members and keep building more memories together for many years to come. Above all, I want to thank ONCE for believing in me and standing by my side for the past 11 years.I know that watching someone grow and change through so many stages of life and continuing to support them along the way is never something to be taken for granted.Thank you for giving me the courage to keep moving forward through your unwavering trust, love, and support.I will continue to fill the years ahead with choices and efforts that stay true to who I am and keep growing as an artist who lives up to all the love and support you’ve given me. Thank you. https://www.instagram.com/p/DevZGTkmTD2/ Jihyo is the third TWICE member to officially leave JYP Entertainment following Jeongyeon and Chaeyoung. Wishing Jihyo all the best on her new start!
Darryn Peterson Could Unlock Lauri Markkanen’s Most Dangerous Role Yet
By drawing defensive gravity and facilitating as a playmaker, the dynamic rookie guard can transform Utah’s All-Star forward into a lethal, off-ball threat who punishes scrambled defenses.
Eagles' Saquon Barkley Trade Proposal Might Make Too Much Sense
It wouldn't be easy, but it could be smart.
Student-produced film captures Ireland sports experience | UNC Hussman School of Journalism and Media
The documentary created by a UNC Hussman School of Journalism and Media team premieres on campus Oct. 22 and Oct. 23. — This story, written by UNC Hussman alumnus Michael Lananna ’14, was originally published at unc.edu. — Carolina senior Anna Laible came up with the idea about a year ago. At the annual UNC Sports and Entertainment Summit, the journalism student walked up to then-athletic director Bubba Cunningham and took a chance. “Hi, Bubba, I’m not sure if you remember me, but I’m part of the student broadcast team from the Olympics,” Laible told him. “I have this idea to do an Ireland documentary on the football team.” Encouraged by the enthusiastic response to the proposal, Laible and a team of students from the UNC Hussman School of Journalism and Media worked diligently to turn that vision into reality. In August, Laible and seven peers traveled to Dublin, Ireland, with the Carolina football team and women’s soccer team. Equipped with video cameras, the student journalists covered both teams during their international games — both wins — and filmed scenes throughout Dublin, interviewing Irish locals, Tar Heel fans and key Carolina figures who helped make the trip possible. Back home, Laible’s team put the finishing touches on the documentary, with its first screening at 6:30 p.m. Oct. 22-23 in Carroll Hall room 111. The project is the latest in a long line of sports documentaries produced under the guidance of C.A. Tuggle, John H. Stembler Jr. Distinguished Professor. Since the 2008 Beijing Olympics, Tuggle and the Hussman school have sent journalism students to cover each of the Summer Games, and Tuggle’s students have also produced documentaries on Carolina teams that win national championships. But this Ireland excursion presented a new kind of opportunity. “This trip is really unique,” Tuggle said. “Bubba liked the idea, so we started working on it, and it’s all because Anna was forward-thinking and assertive.” Laible’s team worked to create a holistic depiction of the Dublin trip, billed as “Much More Than a Game.” The documentary’s 12 chapters cover Irish culture, music, trips to the Guiness Storehouse and the myriad connections between Tar Heels and Ireland. “Our main focus was to make sure we gave a whole encompassing idea of what this experience was like,” Laible said. “We wanted to show not just the student-athletes, but other students, other Carolina fans, Carolina alumni, the music and really incorporate that all in the documentary.” Joining Laible in Dublin were juniors Emily Brietz, Cooper Hall, Eliza Jennings and Katherine McCullough and seniors Molly Malek, May Proctor and Merrily Tew. Those students also traveled to Milan for the 2026 Olympic Winter Games in February. Those kinds of opportunities wouldn’t be possible without the support of UNC Hussman and, in the case of the Ireland trip, the Carolina athletic department. UNC Hussman students create Ireland trip documentary. (Submitted photo) “Never in a million years did I think I would have the opportunity to go to the Olympics or to the Aer Lingus College Football Classic, and now I’m even being presented with potential opportunities go to the Super Bowl,” said Malek, who served in a leadership role with Laible in Dublin. “I think that Carolina does a terrific job of connecting us to these opportunities that almost no other university does. This is a university where you have the opportunity to have an interdisciplinary education and to learn and experience a lot of things all at once.” With the support of UNC Hussman, Tuggle and fellow students like Malek, Laible turned a spur-of-the-moment idea into a documentary. When the film screens, Laible said she’s not quite sure what emotions to expect. “I’m a little worried that I might cry — not that crying is a bad thing,” Laible said, laughing. “But I’m really grateful for so many people helping, and I’m excited for everyone to see it.”
Justice Kagan warns Supreme Court rulings are fueling polarization and undermining democracy
WASHINGTON (AP) — Justice Elena Kagan on Tuesday said voting and elections decisions from her conservative Supreme Court colleagues have helped make the country more politically polarized and less democratic.
Justice Kagan warns Supreme Court rulings are fueling polarization and undermining democracy
WASHINGTON (AP) — Justice Elena Kagan on Tuesday said voting and elections decisions from her conservative Supreme Court colleagues have helped make the country
Jaguars Urged to Trade for $12M CB at Deadline
One of the biggest takeaways from the Jacksonville Jaguars‘ loss to the Houston Texans in Week 6 is that the team has a serious need at cornerback. As the Jaguars sit at 4-2 during the bye week, they will likely be considering trades to make them buyers. Perhaps the best name the Jaguars could add […] The post Jaguars Urged to Trade for $12M CB at Deadline appeared first on HEAVY.
Moment of Science: New electric current test measures coffee quality without tasting
Getting a clue about the perfect brew! Here's how new research could make sure your morning pick-me-up is "not your average Joe". ☕
Would subsidizing weight-loss drugs make health care fairer?
GLP-1 medicines such as Ozempic, Wegovy and Mounjaro have transformed the treatment of obesity, but access to them in Australia increasingly depends on something much less medical: whether you can afford ...
Powder mailed to Arizona officials reflects surge in political threats
Suspicious letters containing white powder have targeted Arizona lawmakers and the state’s elections chief, as experts warn that threats and intimidation against public officials are rising.
Bengals Set to Face Former Teammate This Week in Baltimore
The Bengals will face a familiar foe in Baltimore as former Cincinnati edge rusher Trey Hendrickson looks to make an impact against his former team after returning from injury.
New Richland Lab Could Transform How Scientists Study Microbes and Boost Regional Jobs
The BriefGroundbreaking held Tuesday: PNNL officially began construction on the M2PC lab, a 30,800-square-foot facility funded by the U.S. Department of Energy's Office of Science that will study soil microbes to improve crop productivity and develop new biotechnology applications. The facility will be open to researchers from around the nation and the world.Research timelines could shrink dramatically: The facility's automation and AI capabilities could reduce experiments that currently take six months to just 72 hours, allowing scientists to explore more possibilities faster than ever before.New jobs coming to the Tri-Cities: The project is expected to create positions for automation engineers, AI experts, roboticists, technicians, and skilled craftspeople, with the facility opening in 2029.RICHLAND, Wash. — Pacific Northwest National Laboratory broke ground Tuesday on a first-of-its-kind facility that could accelerate scientific discoveries about the microscopic organisms living in soil—organisms that may hold the key to growing more food and developing new energy technologies.The Microbial Molecular Phenotyping Capability, or M2PC, represents a significant investment in automation and artificial intelligence to speed up research that traditionally takes years to complete. The 30,800-square-foot facility will house more than 100 connected automated instruments designed to study microbes at a pace and scale never before possible.Reshaping Agriculture's FutureThe M2PC facility will not put a new tool directly into a farmer's hands tomorrow morning, but it is actively reshaping the commercial pipeline to solve agriculture's biggest headache with biologicals: inconsistent field performance. For years, PNNL researchers have explored how microbes work and how they might help produce useful materials, advance energy technologies, and address challenges involving critical materials and minerals. But those experiments have been limited by what researchers could accomplish by hand."They can be used to provide nutrients to a plant so that the plant would grow more. So, like increasing your crop productivity, for example," said Douglas Mans, PNNL's Associate Laboratory Director for Integrated Discovery Sciences.PNNL's own research shows soil microbes can help plants access nutrients and withstand drought—benefits that could prove crucial as farmers face growing environmental pressures. The M2PC facility will allow scientists to identify and optimize useful microbes faster than ever before, accelerating the development of biological solutions that actually work consistently in the field.What Makes M2PC UniqueThe Microbial Molecular Phenotyping Capability differs from traditional research labs because it operates as a first-of-its-kind, AI-enabled autonomous laboratory designed to shrink experimental timelines from years down to months or weeks. The M2PC lab will connect more than 100 automated instruments to grow microbes, prepare samples, measure their behavior, and link observations to the molecular processes behind them. Artificial intelligence will help analyze results and guide the next experiments, allowing scientists to explore more questions faster.Deb Gracio, PNNL Director, emphasized the transformative potential during Tuesday's groundbreaking ceremony: "Research that has taken years will become possible in months and hopefully in weeks."That acceleration is already being demonstrated. PNNL's smaller automated lab, called the Anaerobic Microbial Phenotyping Platform or AMP2, completed three experimental cycles in just 72 hours—a process that normally would have taken about six months."That normally would have taken us about six months … and we were able to do that in 72 hours," Mans said.The AMP2 laboratory is not being closed or replaced. Instead, the current 1,800-square-foot laboratory serves as an active prototype and precursor for the much larger M2PC facility. AMP2 will continue operating as a separate lab designed to run anaerobic experiments—those conducted in the absence of oxygen—while M2PC will focus on aerobic research.Broader Applications Beyond AgricultureWhile improving crop productivity is one important application, the M2PC facility is designed to support research into multiple areas critical to national priorities. The lab will advance research into biofuels, manufacturing materials, and energy technologies. It will also help researchers understand how microbes respond to environmental changes and how to design biological systems for biotechnology applications.As a flagship component of the Department of Energy's Genesis Mission, M2PC represents a significant investment in using artificial intelligence and automation to accelerate U.S. scientific discovery. Dorothy Koch, Associate Director of the DOE Office of Science Biological and Environmental Research program, highlighted the facility's importance during the groundbreaking."M2PC will accelerate biological discovery and design," Koch said, noting that the facility is expected to conduct a minimum of 500 strain experiments per week, 100 microbiome experiments per week, and take a million measurements per month.Economic Opportunity for the RegionBeyond the scientific breakthroughs, the M2PC project represents significant economic opportunity for the Tri-Cities region. The facility will require hiring automation engineers, AI experts, technicians skilled in operating robotics, and specialized craftspeople to build and maintain the sophisticated equipment."We're anticipating that type of hiring," Mans said when asked about job creation.PNNL has already begun recruiting talent nationally and internationally for positions related to the smaller AMP2 lab, bringing automation engineers from cities like Boston and San Francisco to work in the region. The M2PC facility is expected to accelerate that trend."This capability won't really exist anywhere else in the world," Mans said, suggesting the facility could become a draw for scientific talent seeking to work on cutting-edge biotechnology research.Timeline and Next StepsThe M2PC facility is expected to open in 2029. Between now and then, construction crews will level and prepare the ground, while the building takes shape. Simultaneously, Ginkgo Bio Works, the automation contractor, will build the facility's automation components off-site so they can be installed as the building is completed.In the interim, PNNL researchers and the broader scientific community will begin planning the first experiments to be conducted in the facility, ensuring research is lined up and ready to begin as soon as the doors open.The groundbreaking ceremony included representatives from the Department of Energy, PNNL leadership, and elected officials at the federal, state, and local levels, underscoring the project's significance to the region and the nation's biotechnology future. News The U.S. Department of Energy Secretary tours Pacific Northwest National Laboratory Dan Hanson, Apple Valley News Now News Beyond DNA: Scientists Explore New Frontiers in Biology Research Dan Hanson, Apple Valley News Now News TRIDEC optimistic that Hanford, PNNL will see funding in national budget Robert Desaulniers News Big picture science: monitoring the Yakima River Basin News PNNL research could shape the future of fighting fentanyl COPYRIGHT 2026 BY APPLE VALLEY NEWS NOW. ALL RIGHTS RESERVED. THIS MATERIAL MAY NOT BE PUBLISHED, BROADCAST, REWRITTEN OR REDISTRIBUTED.
Could Steelers Snatch Pro Bowl WR From Latest Opponent?
The Pittsburgh Steelers could acquire another playmaker from one of their recent opponents. The Pittsburgh Steelers are once again in […]
Toy Story 5, Backrooms and The Breadwinner Vie to Become the Second Biggest Film This Year...
(Welcome to my weekly streaming ratings report, the single best guide to what’s popular in streaming TV and what isn’t. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. If you were forwarded this email, please subscribe to get these insights each week.) Often, people blame “data” for ruining Hollywood, when I’d argue that hype (which can often be debunked by data) is often worse, as you can see in these two headlines. To use a common meme, here’s how it started: and how it’s going: Earlier this year, I read countless (and I mean countless) articles (in almost every mainstream media outlet) about how Heated Rivalry was a huge hit and that it “heated” interest in hockey. But Heated Rivalry wasn’t a huge viewership hit compared to the hype: [ ](https://entertainment.substack.com/p/you-cant-eat-buzzdid-heated-rivalrys) [ You Can’t Eat Buzz…Did Heated Rivalry’s Buzz Translate into Actual Viewership? ](https://entertainment.substack.com/p/you-cant-eat-buzzdid-heated-rivalrys) Entertainment Strategy Guy · Jan 22 [ Read full story ](https://entertainment.substack.com/p/you-cant-eat-buzzdid-heated-rivalrys) In this case, the hype (Heated Rivalry is really popular) belied the data (It didn’t make the top ten charts, meaning it wasn’t a huge hit.1) Even worse, every time I write about this, I get a lot of negative feedback, hence why I only sparingly mention the show these days or add lots of caveats when I write about it, but this just further cements the hype. But companies, and the executives leading them, have to determine strategy based on reality, not media coverage. The NHL committed real marketing dollars to a campaign that didn’t work. Sure enough, the latest NHL season opened to under a million viewers. At some point, you have to focus on what the data says, because real dollars are at stake. And that’s why we have the Streaming Ratings Report! To provide and analyze cold, hard data. Luckily, this week, I can be positive and take a look at a huge opening on streaming, along with a very buzzy horror film that customers kind of like, but don’t really love. And a comedy that tried to rebound on streaming. Today, I’m covering two weeks—21-Sep and 28-Sep—so we have a lot to discuss (nearly 5,000 words worth), including a series of film misses for Netflix, another argument for weekly-released TV shows on streaming, another sitcom tries to avoid the comedy curse, Netflix has two new game shows (one powered by AI), Reacher falling off the charts after a huge run, Prime Video tries its hands at the romcom game**,** a look at the WNBA’s big season, a big night for the VMAs on CBS and MTV, all the flops, bombs and misses, and a whole lot more. (Reminder: The streaming ratings report focuses on the U.S. market and compiles data from Nielsen’s weekly top ten viewership ranks, Luminate’s Top Ten Data, JustWatch and Reelgood interest data, Samba TV household viewership, company datecdotes, Netflix hours viewed data, Google Trends, and IMDb to determine the most popular content. While most data points are current, Nielsen’s data covers the weeks of September 14th to October 4th, 2026. You can find a link to my terminology here.) Subscribe Film - Two Hits and a Miss Come to Streaming… Three very interesting films came to streaming in one week, and I like comparing them since they show the range of theatrical films. One was a huge blockbuster, one was popular, and one was neither. One is a horror film, a buzzy genre; one is a comedy, a struggling genre; and one is an animated family film, the king of the box office. One went to a tiny streamer (HBO Max), one went to a second-tier streamer (Disney+), and one went to the biggest (Netflix). So… If you just went by box office, you’d expect Backrooms—the $197 million grosser, and partner of Obsession for “YouTube Horror Summer”—to dominate on streaming. If you read this report, though, you know that horror films don’t do great on streaming, and that’s the case again. Backrooms opened at 3.8 million hours according to Nielsen, and had 3.9 million hours in its second week. Here’s how that stacks up to other HBO Max films: We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… ...why I don’t buy Backrooms budget… …two new games shows arrive on streaming… …another sitcom struggles… ...another argument for putting out shows weekly on Netflix... ...and a whole lot more, nearly 5,000 words more... ...please subscribe! We can only keep doing this great work with your support. If you want an idea of just how much content you’d get in a full issue, check out this older issue. Coming Soon! Next week, I’ll be taking a look at the eighth season of Hulu’s The Kardashians, answering the question: will this show ever make the charts? If Mormon wives can make it, surely one of social media’s most popular families can as well. Also, Prime Video has a new horror show based on popular IP, Carrie, Netflix has a horror show starring Josh Hartnett, Below, and Apple TV has a UK import, Small Prophets. Plus a bunch of movies like Disclosure Day heading to Peacock, The Housemaid coming to HBO Max, Ben Affleck’s latest on Apple TV, Animals, and Matchbox the Movie on Apple TV, a John Cena action comedy inspired by Hasbro’s toy cars. The week after is even busier! I’ll look at another IP-based horror show, Crystal Lake, a new MCU show on Disney+, VisionQuest, season two of The Lowdown on FX/Hulu, the fourth seasons of The Diplomat on Netflix and Tulsa King on Paramount+, another season of Love is Blind, and four straight-to-streaming films: Netflix’s Sacrifice (starring Chris Evens, Anya-Taylor-Joy, Vincent Cassel, John Malkovich, Salma Hayek. Charlie XCX), Apple TV’s Tenzing (starring Tom Hiddleston and Willem Defoe), Prime Video’s Love of Your Life (Margaret Qualley) and Masterplan (Stanley Tucci) and a whole lot more, somehow. Long term, here’s some huge IP news: a Game of Thrones movie is coming to theaters, Game of Thrones: Aegon’s Conquest in 2029, while Jon Watts (who helmed three of the most recent Spider-Man movies) is directing the next Star Wars trilogy, to be written by Simon Kinberg. I’m cautiously optimistic for both. It feels obvious to say that making good movies matters, but for bets this big (Star Wars is on a swoon, Game of Thrones hasn’t been to theaters yet), the quality has to be there.
Bengals make roster moves after bye week
The Bengals make some roster moves to get better depth in response to injuries.
Exclusive | Democrats Make a Million-Dollar Bet on Florida Governor’s Race
National Democrats have largely withheld major funding for Democrat David Jolly, but are seeing a late-race opportunity.
76ers vs. Knicks live updates, lineups, where to watch: LeBron James, Jaylen Brown make regular-season debuts with Philadelphia against defending champs
Michigan Senate Candidates Make Dueling Pitches to Business Leaders in Detroit
Mike Rogers and Dr. Abdul El-Sayed, the candidates in the tight race, defended their economic policies at the Detroit Economic Club.
Report: Microsoft's Project Helix planned for 2028 at $1,200 to $1,800 price
Xbox maker is also apparently planning its own gaming handheld for next year.
Packers OC Makes Feelings Clear on Josh Jacobs Return
Green Bay Packers OC Adam Stenavich didn't mince words when asked about RB Josh Jacobs' return. The post Packers OC Makes Feelings Clear on Josh Jacobs Return appeared first on HEAVY.
Democrats fear slippage with Black voters makes Michigan Senate race feel ‘far closer than it should’
Michigan's Senate race could decide control of the chamber — and it may come down to Black voters in Detroit and Flint. Where do you think the race stands?
WA leaders push back as federal health cuts threaten millions
Washington lawmakers warn that federal health cuts could cost hospitals billions and hike premiums, drawing debate ahead of the midterms.
Democrats fear slippage with Black voters makes Michigan Senate race feel ‘far closer than it should’
Abdul El-Sayed often talks about building a new and broad coalition of Michigan voters. A looming question in the state’s pivotal Senate race is whether he can keep the old one intact — particularly with the Black voters who are pivotal to any Democratic victory.
Voters are furious about corruption
Public anger could finally make a difference at the polls.
The U.S. has never elected a Black Republican governor. Can Florida?
By many measures, Florida seems like an ideal place for Rep. Byron Donalds to make history as the first Black Republican ever elected governor.
Everton's Right-Back Conundrum Ahead of Arsenal
Everton are preparing to face Arsenal in the Premier League, and David Moyes could have a decision to make at right-back.
Garmin Edge 1060 Cycling GPS Hands-On: Everything You Need to Know!
Everything you need to know about the Garmin Edge 1060, based on initial real-world ride data and hands-on thoughts!
Tonko, Ambrosio make their cases in 20th Congressional District race
Voters in the 20th Congressional District will choose between a longtime Democratic incumbent and a Republican who has never held elected office.
Tonko, Ambrosio make their cases in 20th Congressional District race
Voters in the 20th Congressional District will choose between a longtime Democratic incumbent and a Republican who has never held elected office.
Is This a Make-or-Break Year for Amy Williams?
Amy Williams has spent a decade at the helm of Nebraska women's basketball. Her teams have made the NCAA Tournament more often over the last five years, but she has only made the second round once.
Bucs K McLaughlin Makes NFL History in Week 6 Loss
The Tampa Bay Buccaneers have enjoyed some consistent placekicking from Chase McLaughlin since signing the journeyman back in 2023. On Sunday, he etched his name further in the all-time NFL record books.
Bucs K McLaughlin Makes NFL History in Week 6 Loss
The Tampa Bay Buccaneers have enjoyed some consistent placekicking from Chase McLaughlin since signing the journeyman back in 2023. On Sunday, he etched his name further in the all-time NFL record books.
Zelda: Ocarina of Time Remake File Size Officially Confirmed
You'll never believe how much bigger the Switch 2 game is than the Nintendo 64 original
Sundar Pichai: Google’s Frontier Imperative, Compute Scarcity Dilemmas, Future AI Products and Businesses
Alphabet CEO Sundar Pichai has little patience for doubts about Google’s willingness or capacity to compete at the frontier of AI. His company’s latest Gemini 4 Argon model — long-promised and recently delivered — beats OpenAI and Anthropic’s latest public models on coding, math, science, and knowledge-work benchmarks and has placed Google’s AI back among the world’s best. Amid chatter that Google was fine with good-enough lightweight ‘Flash’ models, Pichai pushed back hard against any suggestion that company is limiting its research ambitions. “We won’t do it any other way,” he told me in a Big Technology Podcast interview recorded this week at Google’s Mountain View headquarters. Pursuing cutting-edge research is costly for Google, requiring compute and chips that otherwise could be sold at a high markup by its cloud business. But Pichai said allocating resources to frontier AI development is “ground zero” for Google. “Our cloud business is at any given moment in time forgoing short-term revenues because we are making compute trade-offs to support frontier AI development,” Pichai told me. In our conversation, we discussed Argon (which Pichai says processed three times as many tokens as Gemini 3 in the 72 hours after launch), AI’s role in developing better models, the AI interface of the future, competition with OpenAI, Google’s partnerships with Anthropic and Apple, data centers in space, and the nature of his optimism. You can read the full conversation, lightly edited for length and clarity, below, or listen to it on Apple Podcasts, Spotify, YouTube, or your podcast app of choice. Alex Kantrowitz: Google is back at the frontier with Gemini 4 Argon, which beats OpenAI’s and Anthropic’s public models on benchmarks spanning coding, math, science, and knowledge work. The conventional wisdom was that Google had given up on the frontier to focus on fast, good-enough models for its products. That was wrong? Sundar Pichai: Very wrong. Look, we are so committed to being at the frontier. It’s in our DNA. We won’t do it any other way. We’ve been thinking about the AI frontier for well over a decade now. The frontier is very dynamic. It’s very competitive. It’s very exciting. I couldn’t be more pleased with how Argon has come together. We took our time with it. We made sure we tested it safely and deployed it carefully. We took a bit longer than our other models, given its capabilities. Across the board, be it for agentic work, knowledge work, coding, creative tasks, Argon is one of the really good frontier models. The first 72 hours since we launched, it’s almost up to 25 trillion tokens used, which is about three times what Gemini 3.0 had in the first 72 hours. And we are capacity constrained as we are serving it. Excited, but there are always areas….. You know, the frontier is very dynamic, and you have to keep evolving the models. There are areas which we can see we need to improve as well. We’ll be at work on all of that as well. Which areas? On any given model, Argon would be across the board better at everything if you just look even two months back. But the space is so evolving. Even on coding, for example, there are pockets where we know we need to do better, and there’s clear feedback. We’ll make it better. The argument for standard models is that they’re already good enough to build great products, with the frontier valuable only for certain tasks. Meta built Muse with good models rather than the best, and Google could put standard models into Maps, Gmail, and Search. Why isn’t that sufficient? It’s definitely not how I have thought about it at all. We are deeply committed to driving the state of the art and actually pushing where this technology can go, all the way from transformers. That’s a journey we’ve been on. You will see us continue to do that. When you’re at the frontier, you get an earlier look into the emerging capabilities, earlier than others, which helps you better prepare for the future. We are fortunate to have a wide set of opportunities across consumer and enterprise. Some of our cloud customers, for sure, want the model at the frontier. The frontier models will be better at developing the next set of models in an era of recursive self-improvement. I would argue it matters there. Internally, we have definitely seen a steep point of inflection by deploying Argon to our developers. It definitely tackles problems which our previous models could not do. Being at the frontier puts you at the innovation frontier and helps you drive that as well. There is room for models of all sizes and capabilities. That’s why we did Flash, Flash-Lite, etc. I agree with you that you can develop very good product experiences with not necessarily the most frontier model, because they tend to be slower and more expensive too. But we care about the Pareto frontier, and we’re committed to doing all of that. You said developing frontier models gives you a look at what’s coming. What do you see on the horizon? What makes this moment so exciting is you build something which you think is a culmination of months of work, and you put it out. You already see clear headroom ahead. We’ve all been working on these agentic, long-horizon capabilities, but clearly the frontier is going to have multiple of these agents working together to do things. That’s an example of an exciting paradigm underway. It’s also clear to me that users, both in consumer and enterprise, will have access to some multi-agent framework for them, working all the time doing things. It feels like a moment of infinite possibilities. Sergey Brin said one of Argon’s core innovations was relying more on the model to help develop the model. Yet incidents involving OpenAI’s bots breaking containment and Google’s bots accessing a site they shouldn’t have suggest these systems still aren’t perfectly aligned. Isn’t there reasonable cause for concern about accelerating toward recursive self-improvement? There are three parts to your question. Let’s first talk about RSI itself. You’re right, Sergey mentioned RSI being a critical contributor as we are developing Argon. But to be very clear, today, in a continuum, we are pretty far from the end state of RSI or something like that. The right way to describe it is you have RSI loops along with AI researchers in various aspects of model development. You almost have agents helping AI researchers in some automated way work together to build these models. It’s good to at least understand where we are today, and it’s super exciting. I expect that continuum to keep making progress as we go into next year. The second question is around safety. Security comes from defense in depth. You’re talking about alignment, obviously. We all are doing a lot of work to make sure the models are as aligned as possible. But it’s an active area of research, and there are clear gaps. That’s not the only thing we rely on. You have the work you do on alignment, but beyond that, we put a lot of effort into real-time monitoring as these models are working. Making sure you have good telemetry into what’s happening so that you can intervene in real time if you see unexpected behaviors. How you do that, the architecture with which you do that, how you make sure it’s all sandboxed and isolated in a way that it can continue doing its job during real-time monitoring — these are all areas of investment. Obviously, when we deploy these models, giving customers, enterprises, control, both with real-time monitoring, but their ability to decide where they deploy, what type of data which models ever have access to, etc. All that work is very, very important, and we are doing a lot of that. As an industry, we need to constantly up our game and take the time to do all this stuff, including dedicating the compute required to make sure you can safely deploy these models. The third part is: Is it all enough? This is why there are a lot of conversations in the industry, and I think it’s reasonable to be worried. The right way to approach something you worry about is early on thinking about what more we can do. As an industry, you’re definitely seeing increased levels of work on alignment, testing for safety, etc., as we deploy these models. The next step would be developing better standards so there are cross-industry standards of how we do these things, including the ability to evaluate using independent evaluators. If you look at areas like financial controls, we have accounting standards, we have independent auditors. Those are all the next natural steps for us as an industry to work toward, and regulation will end up playing a role as we go through all of that as well. Google pursues both language models and world models, while some other AI companies like OpenAI have focused more heavily on LLMs as the path to AGI. Why is world-model research important to you? As humans, you obviously perceive the world around you, and you’re taking all those inputs. Making sure these models are able to understand the laws of physics, simulate the world in high fidelity. All that, I think, are key enabling blocks for intelligence. We are working across all possible applications of this. Take an area like robotics. It’s not an accident: If you look at embodied reasoning benchmarks, Argon is state of the art. That all comes from our experience building world models. Inherently, I would expect there will be architectures which will converge all of this in the future. But for us, we view this as, today, this jagged frontier that is intelligence. We want to be at the frontier of all the possible approaches, and that will help us both drive better research, better insights, and develop a much better AGI model, is how we think about it. Some people argue Google should focus on selling its computing resources rather than using them for AI research. Cloud wants to sell compute at a high markup, while researchers need a very big computer to build the best models. How do you balance those demands? Ground zero for us is making sure we are investing in the compute that’s needed to be at the AI frontier. In 2015, I set the company to be AI-first. AI is that key horizontal ingredient across everything we do, all the way from Search to Cloud to Waymo. That is ground zero for us, making sure both for research and developing the models that we have enough compute needed. Beyond that, we have these independent businesses which each have their own long-range plans. They’re using those long-range plans to project forward, and we plan for compute for all of them. The cloud team, they have a business and they have a projection and they have demand signals. They have committed contracts. With that help, we can plan on a long-term compute trajectory for them. We’re fortunate to have this wide set of opportunities. There’s no company in the world which isn’t making trade-offs at any given moment in time. But the first principles we operate on is making sure we have enough compute to invest in the frontier, and that’s non-negotiable, and everything else works on top. Remember, we are building our own compute, our own data centers. There are long lead times. The compute we have today is a function of decisions I made in 2024. Even if you think back to a year from today, last year the agentic coding takeoff hadn’t happened. Today, obviously, when you sit and look at anything, everyone is short—not just us, other companies—and everyone wishes you had two times what you had planned for. That comes with the territory. At any given moment in time, we are planning for what we would need two to three years out in the future. You’re going to find some decisions you make may look suboptimal two years out, depending on where the state of the art is. I don’t spend too much time thinking about it. The way I think about compute allocation is making sure Google DeepMind, both for research and frontier model development, is cutting edge in terms of compute access. After that, we plan for all our businesses. It’s great we can provide our compute to other people too, like we have done. It allows us to scale that up, get real tests for it in the widest application set possible, test it in the real world, and make sure we are at the cutting edge of technology at every layer of our AI stack as well. Ben Horowitz relayed on a podcast that Andy Jassy had said compute was sold out until 2028. Are you seeing the same thing? If today a customer is coming out and asking us for compute in ’27, that is incredibly difficult to do. Even last year we went out and leased some short-term compute to accommodate some customers and help them out. But yes, we are all dealing with similar timelines. Every major technology shift seems to involve overbuilding, from railroads to fiber. Do you think that’s happening here? It depends on the time frames you’re looking at. This level of build, if I take a long enough time frame, it makes complete sense to me. We are at early stages of the most consequential technology ever, and this is not like fiber. It’s not dark. We are using it. We are capacity constrained on a daily basis. The applications, the underlying technology is improving rapidly. But running a company, the way I work through the moment is you look at your demand signals. You look at your committed revenue opportunities that you’re getting in the form of contracts. You balance that with the underlying technical capability, or internally you balance how we are using it internally, the model trajectories. Based on all that, you take a disciplined approach—a confident, aggressive, but disciplined approach—to plan out compute. But when you talk about the broader economy as a whole, you’re having people operate with various levels of risk. I focus on what I can control as a company and plan through it. If your question is, can there be an overbuild? Yes, because you can have some constrained components. Remember, what matters is a set of everything you need to build out that compute. Memory, electricity, electricians…. Land. Like 2,000 components or more. You could get constrained at some point. There could be things which cause bottlenecks, and then you could have overbuilds. There could be external shocks to the economy. There are macro risks. All that is possible at any given time. But am I confident that the compute we are planning for, we will have uses for it given enough time? Absolutely, yes. I was in the room when you said AI would be as profound as fire and electricity. If you believe that, shouldn’t you give researchers the biggest possible computer, even at the expense of today’s cloud profits? We’re all doing some form of that. Our cloud business is at any given moment in time forgoing short-term revenues because we are making compute trade-offs to support frontier AI development. What you’re seeing is true already. But you want to be thoughtful. Even our AI researchers have some constraints, which are also good. That’s what inspires creativity. That’s what helps you come up with a more efficient algorithmic breakthrough, maybe to use less memory. What we are committed to is to invest what’s needed to stay at the frontier. OpenAI President Greg Brockman told me a few months ago that the ideal AI product might have no interface at all—just as natural as conversation. What do you think the interface looks like in the age of AI? Computing historically has been humans adapting to computing. With AI, it’ll be the other way around. The technology will adapt seamlessly to how humans live and go about their day-to-day life. You want to be able to speak to that AI when you want to. It has context. It can be persistently running somewhere, give you continuity. You’re not dealing with a lot of complexity. It’s natural. All that makes sense to me. That doesn’t mean it won’t have any interface, however. Nowadays, even on my phone, Gemini voice models are so good. I can just press the microphone button. I can just ramble. That’s why we call it Rambler. I can ramble. It intelligently corrects with my personal context. Even my friends’ names, weird names, it gets it right, even if it first guesses it wrong. It’s amazing. I’m not going in, backspacing, editing once I finish saying it. It’s remarkable how good it’s gotten. But there are going to be moments you will need an interface. You may want to entertain yourself. You may want to watch a video. You may ask your AI to create something, and you want to watch it, consume it. The way I think about it is, you want it to be as seamless and as natural as possible, and that you are not doing the hard work adapting to whatever the interface is. The technology is adapting to how you’re working at any given moment in time. When I asked Sam Altman about competition from Google, he argued that OpenAI was building AI-native products and implied Google was bolting AI onto existing ones. Do you accept that framing, and can a “bolt-on” compete with an AI-native product? First of all, it’s a very dynamic moment. We are all pushing each other. OpenAI has pushed us as a company too. This is not just we are doing something to them. Far from it. Yes, Google went into its own version of a code red too. In the AI moment, all of us have to respond with varying levels of urgency at any given moment in time. We are constantly building new products as well. Gemini was built from the ground up as a product—the Gemini app I’m talking about. Or tomorrow, as all of us are adapting to agents, are you bolting agents onto ChatGPT, or are they building it natively? How would you think about that? You can always put these questions back. I don’t think of it that way. I think of it as you want to build world-class product experiences that are AI-native and they are winning. Some of it is adapting products, some of it is rethinking new experiences. They will all be part of how you approach this moment. How do you expect to make money from these AI interfaces? If an agent recommends a product and I buy it, should it take a cut of the sale, even if that’s disclosed? I’m going to put enterprise aside. Consumers are going to increasingly value this technology. Take software developers today. Developers are willing to pay for these coding models because it really helps make them more productive. Nobody would want to code the way they were coding three years ago, or even the same time last year. When you’re delivering value, there’s value to be had. I’ve never seen examples where consumer products really scale to billions of users, where people are using it intensely, and haven’t had monetization to go along with it. If you’re providing value to people, there is inherent value to be had. The nature of it may change. You’re asking a scenario in which agents are doing stuff for you. At the end of the day, you will have commercial needs. The agents need to fulfill those commercial needs. The providers on the other side are going to see value in that. There’s going to be some mechanism by which it gets fleshed out. That’s what an efficient system does. But what matters is that you’re building those world-class consumer experiences. I promised myself one product feature request: Can you make Gemini-powered search in Gmail as good as searching Gmail through ChatGPT? What’s going on here? One of the exciting things we announced recently is the unified Gemini agent for enterprise, and we’re bringing that to consumers. These are persistent agents which run 24/7 in the cloud. We’re spinning up a micro VM effectively for every query, and from the runtime, the harness, the model—it’s all a headless service. It’ll work everywhere, and it has your context with you. You can address this agent whether you’re in Workspace, in Search, in Gemini. Agents are going to drive this unification from a customer experience, which people are looking for. When you have a broad product portfolio and you’re moving forward fast, there are always areas where you’re moving forward faster than some other areas. That’s valid feedback. But we are putting a lot of time and effort into making sure, as we build out our agentic experience, that unification and that capability works well across all these services. People have asked where Google’s equivalent of Muse or Dots is. Do you anticipate creating a new product to compete with them? Our goal with Gemini is to be a personal, proactive, and powerful assistant. That’s what we are working toward. You saw us describe the early versions of it at Google I/O this year with Spark. Effectively, already, if you open the Gemini app as a Pro or an Ultra user, you see Chat and Task, and they start giving you that agentic experience. With Argon now, that capability is dramatically accelerated. What we announced recently in our enterprise event, we are bringing that to consumers as well. Soon in Gemini, you will be able to ask something, and it’s a continuum. You don’t need to think about whether you’re asking a chat or an agentic task. It’ll just automatically do the right thing, and it can work persistently in the background securely and get things done for you. Already, empirically, when I look at what’s coming into Gemini in our app, last year you would have tagged them and most of them would have been chats. But a steadily growing percentage is already agentic tasks in Gemini. Yes, we are going to bring personal agents to our consumers. It’ll work in the Gemini app. It’ll work in Google Search. It’ll work in Gmail. You can address it, call it, etc. We want to make sure we’re getting it right. It’ll be powered by Argon, and we are very excited to bring it to our users. Google has invested and committed tens of billions of dollars to Anthropic. What do you see in Dario Amodei that makes you want such a deep investment and partnership? Very early on, when we looked at the founding team of Anthropic, it was very clear to us this was a world-class team which was involved in some of the earliest GPT models. We were quickly able to assess that they would be at the frontier. We’ve always tried to identify and partner with companies which would be at the cutting edge of technology. We’ve done that with SpaceX. We’ve done that with Anthropic. That’s what we saw, and we had a chance to partner. Is your partnership with Apple to license Gemini for Siri expanding, contracting, or standing still? For both us and Apple, that partnership was about translating the capabilities of AI into better experiences for users. I thought Apple has done a phenomenal job of incorporating—they customize these models and build it into Siri—and it’s been great to see the reception. We are committed to doing more. You’re going to do more with them? There’s nothing specific to comment, but it’s a partnership. It’s working well. What have you learned so far about the feasibility of data centers in space? It’s a very exciting project. Projects like this remind me—I still recall that moment in the desert for the DARPA Grand Challenge, watching the Stanley car compete in it, which ended up being the basis for Waymo. With all these technologies, you’re at a moment in time where it looks a bit like sci-fi, but 10 to 20 years down the line, it’s actually working in a meaningful way. I feel the same in space. We’ve always believed in betting big on these technologies. Quantum has been a great example of it. We’re probably 10 years into the journey. Waymo, we are almost 20 years into the journey. Space, we are two to three years into the journey. It’s clear to me that it’s an approach which will make a lot of sense in the future. Being in sub-synchronous orbits with 24/7 access to the most abundant form of energy we have access to will make a lot of sense for this exponential increase in compute that we are going to need. Having said that, this is a challenging project. The team has disciplined milestones. It was a super exciting milestone to send the TPUs up to space. Sometime, as we are speaking, we are expecting a “hello world” moment from them. I look forward to seeing that happen, and we’ll continue investing here too. You previously said 25% of the code written within Google was written by AI. What’s the number today? That number in our world today is meaningless in the sense that every part of what we now touch is influenced by AI deeply. What we are tracking with Argon, for example, it’s been a point of inflection. People are using Argon to really go tackle complex projects, including projects which affect millions of lines of code. In the four weeks since we have launched Argon, we have seen a 30% increase in CLs, and more importantly, almost a similar increase—a one-third decrease in rollbacks. People are writing code more productively and better code with it. We are tracking it with newer metrics now. How are you dealing with opposition to data centers? If you can’t build in the U.S. the way you want to, where else do you go? We’re very committed to building our data centers very responsibly. When I look at our largest data centers in some of the communities where we have been the longest, I visit them, I talk to people. There are people who come and tell us their kids have gone to college because of our investments in these communities, and we’ve grown in those communities. To me, this is about doing it right. Engaging with the communities early, doing it transparently. We are committed to making sure we are bringing incremental power, and we cover 100% of the cost of our power needs for these projects. It’s understanding the impact on neighborhoods and making sure you’re working thoroughly to address them. Done rightly, you can continue making progress. But we are constantly taking feedback into account. I do worry not everyone operates the same way. People have been surprised by data centers showing up in their backyard. Those are all important. As an industry, we should continue to do better. But part of the reason, in a 20-year time frame, we are thinking about things like data centers in space is making sure we are able to put these data centers where maybe the trade-offs will be different. What unproven area of AI is Google working hardest to crack? Is it continual learning—getting models to keep updating after release—or something else? There are multiple parallel paths. You saw with Argon we have a million output tokens. With our Gemini models early on, we had a one-million context window on the input side. These are all examples of breakthroughs we are constantly working on. How do you think about synthetic data? How do you think about continual learning? How do you think about more efficient architectures? We do dedicate a meaningful percentage of our compute to these research bets too. It always goes hand in hand, including our world models. Those are all bets we are placing. Sometimes, as part of these bets, there are ideas that emerge which just make their way into the mainline models. Maybe we don’t fully talk about it, but we have multiple steps in these areas. Working in technology requires optimism that building something will improve the world, but those bets can leave real consequences when they fail. I recently returned to a town in El Salvador where enthusiasm for Bitcoin had given way to unfinished construction and something resembling a ghost town. How do you maintain the optimism you spoke about in your Stanford commencement address while accounting for those risks? I genuinely have a deep conviction that improving technology and improving access to technology makes people’s lives better. It’s been my personal experience in my life, out of which comes that deep conviction, optimism. But with that, I’ve always felt humanity’s journey is always about working hard to harness that technology to make it work well for society. The optimism is not an optimism that you just build whatever you want, whenever. You work hard to make sure you’re building technology in the service of humanity, to make the human condition better. That’s got to be the defining goal as we are approaching it. With that framework, I’m very, very optimistic. We are in very early stages of the kind of progress that we are going to see on many areas. We’re all talking about areas like healthcare. A lot of the progress is ahead. The ability to make things in a fundamentally cheaper way on many things where things have been getting expensive for a long, long time, discovering new materials, etc., which really bend the curve—it’s tough to step today and understand the impact of all that, but they’re going to be very profound. I’m very optimistic, but we have to be rightfully concerned about all the ways this technology can go wrong. Sundar, I know you don’t do many of these. Thank you. Thanks, Alex. Appreciate it.
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A note to readers: Science, accountability and elections
Dear readers, As early voting begins, I wanted to share some news — and why it connects to the decisions we make at the ballot box. I’ve been selected for the inaugural cohort of the South Atlantic Climate Journalism Hub mentorship program, hosted by Covering Climate Now. I’m excited to join this group, learn from scientists and fellow journalists, and expand my science reporting. Science directly ties to governance. Local officials make decisions about where development goes, how infrastructure is maintained, what emergency preparations receive funding, and how communities rebuild after disasters. Understanding the evidence behind those decisions helps us evaluate whether our government is serving us well. Here in western North Carolina, those connections are all around us, in Lake Lure and beyond. Flood maps inform decisions about property and development. Engineering assessments help identify risks at dams and bridges. Rainfall forecasts guide emergency preparations. Geological information helps explain landslide hazards. Water testing gives communities information they need to assess conditions. Meteorologists’ knowledge and public perception of weather events shape public safety. Each involves scientific or technical knowledge. Each also raises questions about public responsibility: What did officials know? How did they use that information? What did they tell the public? What did taxpayers receive for their money? A study can identify a problem. Elected officials still have to decide what to do about it, how to pay for it, and how to explain their choices. Reporting should examine both the evidence and the response. That is where I want to strengthen my work. My reporting on Helene recovery, infrastructure, flooding, public safety, and public spending has repeatedly brought me to questions that require scientific expertise alongside public records. This mentorship may help me better understand the research, ask more precise questions, and explain the answers clearly. I also bring the perspective of someone living with these concerns. I live downstream of Lake Lure Dam, and landslides affected my property during Helene. Those experiences bring urgency to my questions. Careful reporting helps establish the answers. Readers deserve to know what the evidence shows, where uncertainty remains, and whether officials accurately describe the information guiding their decisions. You also deserve scrutiny of proposed solutions: what they cost, what they are expected to accomplish, and what risks remain. Access to that information matters. As a mostly deaf journalist who relies on written communication, I will continue pressing for written public warnings, records, and explanations that people can read and use in real time. As you consider the candidates seeking your vote, consider how they approach evidence, preparedness, and transparency. Do they support local journalism, even when it’s not parroting a press release? Do they explain weather events clearly in plain English and explain their decisions after them? Make supporting records available? Acknowledge uncertainty? Follow through when a report identifies a risk? Those are practical questions about governing. Thank you for supporting Cops & Congress and the work that makes these questions part of the public conversation. I’m grateful to David Dickson and the CC Now team for this opportunity, and I look forward to bringing what I learn back to you. Annie DanceEditor & Publisher, Cops & Congress — Learn more about this newsletter, ethics policy, how you can help shape this work, and support it. Follow on X and Facebook. Send constructive criticism, fan mail, and tips with public documents for future stories: CopsandCongress@gmail.com ICYMI: View the Cops & Congress archive — Annie Dance is the publisher of Cops & Congress, a newsletter that analyzes what happens when crime, courts, disaster, democracy, and small-town policies collide. Views expressed here are covered by the First Amendment. Dance has a Bachelor of Arts from Manhattan University in Communication with a focus in Journalism and Government. She has been a journalist for over 20 years. Share Upgrade now or give a gift subscription
Bill Nye "The Science Guy" makes surprise appearance in Rutherford County
Nashville News, Weather, and Sports
Hammer and Rails Readers Reacts Survey: Purdue Men’s Basketball Newcomers
Which newcomer will make the biggest impact on Purdue basketball this season?
So What Is Socialism, Anyway?
In a world dominated by neoliberal market fundamentalism, “socialism” is what will make a more moderate, regulated form of capitalism work for most people.
The art of science: MU students make art inspired by biology, anthropology departments
HUNTINGTON — Some artists would get mad if someone drove over their artwork, but that wasn’t the case in Pullman Square on Friday evening.
Bigfoot to Bojangles: How a Charlotte family built a business on make-believe
Long before the store became a Charlotte fixture, it started with a phone call, a rack of costumes and a couple willing to take a chance.
Threats of political violence soar in Australia’s ‘online echo chamber’
Independent lawmaker Helen Haines was in critical condition after being struck deliberately by a car.
Guided search helps Kentuckians navigate treatment, mental health and recovery resources
A new guided search feature from FindHelpNow.org makes it easier for Kentuckians to find substance use disorder treatment, mental health care and recovery resources that fit their needs.
Pfizer makes ‘business decision’ to end phase 2 trial of autoimmune drug as program’s future uncertain
Pfizer has called time on a phase 2 trial of its CXCR5 antibody in an autoimmune blood disorder, with the company tight-lipped on whether this marks the end of the road for the asset. The Big Pharma had been evaluating the therapy, dubbed PF-06835375, in a phase 2 study of 61 patients with primary immune thrombocytopenia (ITP) that kicked off in 2022, according to the federal trials register. However, Pfizer confirmed to Fierce on Monday that this study had been terminated “due to a business decision.” “The decision to terminate the trial was not based on any safety concerns,” a spokesperson pointed out. At time of publication, PF-06835375 remained listed on Pfizer’s website for both ITP and lupus. A phase 1 study in lupus wrapped up in 2022, according to the trials database. ITP is an autoimmune disorder characterized by a low platelet count. Novartis was at one point evaluating its B-cell-depleting antibody ianalumab—recently approved as Fabhalta to treat immunoglobulin A nephropathy—as a potential treatment ITP. But the therapy struggled to demonstrate a benefit in the clinic for this indication. When contacted by Fierce, Pfizer wouldn’t confirm whether all work on PF-06835375 has been halted, and whether the company has any other plans to explore C-X-C chemokine receptor type 5 (CXCR5) as a mechanism. CXCR5 is found in blood cancers such as diffuse large B-cell lymphoma and mantle cell lymphoma chemokine receptor. However, there is little expression in normal tissue, which has led some drug developers to explore its potential. Vincerx Pharma had at one point been planning to take an anti-CXCR5 ADC into the clinic to treat B-cell malignancies, but that ambition was scrapped due to cash constraints. Where Big Pharma is placing its bets is one of the hot topics being discussed at Fierce Biotech's high-impact event in London next month. Find out more information and register by clicking on the banner below: [ ](https://qtxasset.com/quartz/qcloud5/media/image/where_big_pharma_is_placing_its_bets.png?VersionId=B8JrRbJ.pFUSK1pJgjeWHLGm_18RdLAy)
Penguins Make Brutal Injury Announcement Against Mammoth
The Pittsburgh Penguins were in action on Monday against the Utah Mammoth, making a visit to Salt Lake City to take on their hosts at Delta Center. Unfortunately, they were defeated by a 5-4 final score – but that wasn’t the only loss they suffered.Not only did they lose the game, but the Penguins also […] The post Penguins Make Brutal Injury Announcement Against Mammoth appeared first on HEAVY.
James Maddison marks first Tottenham start in nearly 18 months with stunning goal in first Premier League win of season
Tottenham playmaker struck opener in 3-1 win over Coventry which moved side off foot of Premier League; the 29-year-old was making his first start following torrid long lay-off after suffering an ACL injury
Nvidia CEO urges German manufacturers to adopt AI
FRANKFURT, Germany — Nvidia CEO Jensen Huang urged Germany’s makers of cars and industrial machines to quickly adopt artificial intelligence to “re-engineer” the country’s struggling business model by tapping its
A materials-first approach to entertainment
It's our duty to tell professionals from the creative industry what it really entails to make 3D printing part of its production environment.
Volkswagen bet on Xpeng to save its China business. It’s not going to plan
By Ju-min Park and Christina Amann BEIJING/BERLIN, Oct 20 (Reuters) - When Volkswagen turned to EV maker Xpeng in 2023 to help fix its flailing Chinese business, executives touted the partnership as a shortcut to developing cars tailored for China at t...
COMCARE provides mental health support at Stryker Sports Complex as teams return to field
“It can be really hard to go to the scene of a trauma, and we want to make sure people feel safe," said the director of COMCARE.
Bears Receive New Trade Take on Colts DT DeForest Buckner
Harrison Graham of Chat Sports believe the Bears should look to make a trade for Colts defensive tackle DeForest Buckner. The post Bears Receive New Trade Take on Colts DT DeForest Buckner appeared first on HEAVY.
Lakers Depth Chart For Final Roster After Dalton Knecht Release
T he news of the Los Angeles Lakers releasing Dalton Knecht confirms the final roster entering the NBA regular season. Bronny James and Jaden Hardy survived the cut and will make the roster to keep their jobs. Knecht was not expected to get strong playing time, but he removes a player who could give the […] The post Lakers Depth Chart For Final Roster After Dalton Knecht Release appeared first on HEAVY.
Actor, activist Jane Fonda makes appearances, endorsements in Oregon
Actor and progressive activist Jane Fonda made appearances in Salem and Portland to support Oregon Democratic candidates for the November election.
Spurs Roster: Carter Bryant Makes Strong Case for Bigger Role
Carter Bryant is making a case to be a normal rotational player on the Spurs roster. Against the Suns on October 14th, he had 16 points and hit four threes. With improved shooting and improved defense, his case for a lot more playing time is strong. The question becomes whether or not he can stay […] The post Spurs Roster: Carter Bryant Makes Strong Case for Bigger Role appeared first on HEAVY.
Colts’ GM Firing Could Have Eagles Watching Closely
The Indianapolis Colts made a big move at the top of the week, as they are cutting ties with their GM, Chris Ballard. The 57-year-old executive leaves his position after serving as the front office leader since 2017. The Colts make that move after a 2-4 start to the season. The NFL will watch closely […] The post Colts’ GM Firing Could Have Eagles Watching Closely appeared first on HEAVY.
Toppenish School District receives $7.5 million federal grant to expand mental health services for students
The BriefThe Toppenish School District has been awarded up to $7.5 million through Project AWARE (Advancing Wellness and Resiliency in Education), a federal grant administered by the Substance Abuse and Mental Health Services Administration (SAMHSA).The grant will provide up to $1.5 million annually over five years to expand mental health services, strengthen substance use prevention and intervention, and improve access to support for students.District officials say the funding will help address identified gaps in services, particularly drug and alcohol counseling at the high school level, and will allow the district to build capacity for long-term mental health support.TOPPENISH, WASHINGTON — The Toppenish School District has been awarded up to $7.5 million through Project AWARE (Advancing Wellness and Resiliency in Education), a federal grant administered by the Substance Abuse and Mental Health Services Administration (SAMHSA), to expand mental health services and substance use prevention for students.District officials said access to mental health resources has been limited, making it difficult for some students and families to get the support they need. The federal Project AWARE grant will help address those challenges by bringing schools and local healthcare providers together to better support students.The grant will provide up to $1.5 million annually over five years to expand mental health services, strengthen substance use prevention and intervention, and improve access to support for Toppenish students. Deputy Superintendent Dr. Jeff Camero said the district is focused on coordinating with service providers in the area to work as a unified team."We made the awareness with the grant. But looking at all the service providers in the area and how can we all together work as a team?" Camero said.Camero said the district wants to use those resources to reach students earlier and provide more support for those struggling with their mental health. The district plans to address a range of mental health challenges, from anxiety and depression to youth suicide risk. Camero emphasized the importance of supporting students in grades eight through twelve, where suicide rates are a particular concern."Making sure from anxiety to depression, making sure that we can help support our students at those levels, but also the youth suicide risk, looking at that as a top in this area, in our grades, you know, eight, for example, eight through 12, looking at suicide rate and looking at how whether we look at the ACES or whatever program we're looking at, that's federal, how that connects and how we can better serve our students with this extra funding," Camero said.The funding will allow the district to bring in additional staff, including mental health and substance use specialists, to work directly with students and connect families with community resources. The district is already posting positions, including a director role, with additional positions expected to follow.District officials are also thinking beyond the grant's five-year timeline. Brittany Kaple, Director of Public Relations for the Toppenish School District, said the intent is to build capacity and establish connections that will sustain mental health services even after the grant funding ends."We do have the director position already posted, with some of our other positions following really close behind that. But the intent is to, you know, it's a five-year grant, so those positions would be funded for that five years. But there's also the intent to build capacity and make those connections so that at the end of the grant, when that money, you know, if that money is not renewed," Kaple said.As student mental health needs continue to evolve, access to drug and alcohol counseling has become an important priority for the district. Kaple said teachers and staff have been raising concerns about the need for more support, especially at the high school level."And that was something that was also an identified need by our high school staff when the superintendent met with them last school year. They said that that was a really great need, something that they felt was a gap in services that we were providing for our students. And so this is going to be one way to help support that need," Kaple said.The Toppenish School District says its goal is to ensure students and families have access to the support they need, both now and in the years ahead. Additional positions, including drug and alcohol counselors and family engagement specialists, are expected to be posted in the coming weeks. News Sunnyside City Council navigates 2027 budget planning Monique Garcia News "Dancing with the Stars" champion J.R. Martinez shares message of resilience during Central Washington visit Tyler Wargo News Toppenish, Mattawa educators honored at state Educator of the Year Awards Erin Wencl News Kennewick educator named 2027 Washington Teacher of the Year Erin Wencl News Voters to decide the next Yakima County Sheriff Monique Garcia COPYRIGHT 2026 BY APPLE VALLEY NEWS NOW. ALL RIGHTS RESERVED. THIS MATERIAL MAY NOT BE PUBLISHED, BROADCAST, REWRITTEN OR REDISTRIBUTED.
5 Apple TV Features Every Family Should Be Using
Apple TV has a number of surprising features that you may not be aware of, but you should definitely consider using them to make your life easier.
“Cellar Door” ending explained: What’s really behind the cellar door?
Laurence Fishburne makes a married couple an offer they should’ve refused in the 2024 horror thriller.
Advancing Women's Health to Improve Outcomes in All Phases of Life
The Executive Order (“EO”) makes it federal policy to prioritize turning women’s health research into better clinical care at every life stage, and it directs HHS, through NIH, to set up a new Women’s Health Division within 90 days. In coordination with the NIH Office of Research on Women’s Health, the Division will focus on, among other things, understudied women’s health conditions, greater inclusion of women and girls in clinical trials and grant recipients’ adherence to NIH's policy on sex as a biological variable. The EO also creates a White House Women’s Health Task Force, co-chaired by the Secretary of HHS and the Assistant to the President and Chief of Staff and composed of officials from other departments and agencies.
Iowa 55-hour ‘FilmSprint’ comes to Cedar Rapids this fall
Cedar Rapids Independent Filmmakers launches the Iowa 55-Hour FilmSprint, Nov. 6-8, 2026, challenging teams to write, shoot and edit a short film with Iowa-themed secret elements.
How will the riots in France affect the country’s politics?
For weeks, people in France have been protesting over the cost of living and school conditions. But this weekend, many protests turned violent -- and now French officials have implemented a curfew to quell the violence. The country’s far-right is seizing the moment to make a case for their policies.This episode was produced by Sophia Paliza-Carre and Karen Zamora, with audio engineering by Damian Herring. Our director is Kathryn Fink.It was edited by Mallory Yu and Tinbete Ermyas.Our interim executive producer is Courtney Dorning.Support public media with NPR+ and enjoy perks for over 25 podcasts like this one. This show’s perks include bonus episodes and sponsor-free listening. Learn more at plus.npr.org.
Mines Museum of Earth Science event makes science spooky
Not many Halloween events send trick-or-treaters home with geodes, but the Mines Museum of Earth Science’s annual Spooktacular is one of them.
Mines Museum of Earth Science event makes science spooky
Not many Halloween events send trick-or-treaters home with geodes, but the Mines Museum of Earth Science’s annual Spooktacular is one of them.
Lakers Make Final Roster Cut Before Beginning of Season
The Los Angeles Lakers waived forward Dalton Knecht on Monday, reducing the size of their roster to 15 just before their Monday deadline. The post Lakers Make Final Roster Cut Before Beginning of Season appeared first on LA Sports Report.